Assay ID | Title | Year | Journal | Article |
AID1443027 | Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate preincubated for 10 mins followed by NADPH addition measured after 15 mins | 2017 | Bioorganic & medicinal chemistry letters, 04-15, Volume: 27, Issue:8
| Effects of 6-paradol, an unsaturated ketone from gingers, on cytochrome P450-mediated drug metabolism. |
AID1646334 | Aggregation-based inhibition of human recombinant AKR1B1 assessed as D,L-glyceraldehyde reduction at 300 uM incubated in sodium phosphate buffer at pH 6.2 in presence of NADPH and 0.05% Triton X-100 by detergent-addition assay | 2020 | Bioorganic & medicinal chemistry letters, 01-15, Volume: 30, Issue:2
| Early identification of promiscuous attributes of aldose reductase inhibitors using a DMSO-perturbation assay. |
AID480936 | Cytotoxicity against human Caco-2 cells at 50 ug/ml | 2010 | Bioorganic & medicinal chemistry, May-01, Volume: 18, Issue:9
| Identification of serotonin 5-HT1A receptor partial agonists in ginger. |
AID480941 | Antagonist activity at 5HT1A receptor expressed in HEK293 cells assessed as inhibition of 8-OH-DPAT-induced [S35]GTPgammaS binding by scintillation counting | 2010 | Bioorganic & medicinal chemistry, May-01, Volume: 18, Issue:9
| Identification of serotonin 5-HT1A receptor partial agonists in ginger. |
AID421740 | Antiallergic activity in mIgE-DNP and DNP-BSA-stimulated rat RBL2H3 cells assessed as inhibition of beta-hexosaminidase release at 1 uM pretreated before mIgE-DNP challenge measured after 12 hrs relative to control | 2009 | Journal of natural products, May-22, Volume: 72, Issue:5
| Antiallergic potential on RBL-2H3 cells of some phenolic constituents of Zingiber officinale (ginger). |
AID421742 | Antiallergic activity in mIgE-DNP and DNP-BSA-stimulated rat RBL2H3 cells assessed as inhibition of beta-hexosaminidase release at 200 uM pretreated before mIgE-DNP challenge measured after 12 hrs | 2009 | Journal of natural products, May-22, Volume: 72, Issue:5
| Antiallergic potential on RBL-2H3 cells of some phenolic constituents of Zingiber officinale (ginger). |
AID421739 | Cytotoxicity against rat RBL2H3 cells at 120 uM after 12 hrs by MTT assay | 2009 | Journal of natural products, May-22, Volume: 72, Issue:5
| Antiallergic potential on RBL-2H3 cells of some phenolic constituents of Zingiber officinale (ginger). |
AID1443024 | Inhibition of CYP2C19 in human liver microsomes using (S)-mephenytoin as substrate preincubated for 10 mins followed by NADPH addition measured after 40 mins | 2017 | Bioorganic & medicinal chemistry letters, 04-15, Volume: 27, Issue:8
| Effects of 6-paradol, an unsaturated ketone from gingers, on cytochrome P450-mediated drug metabolism. |
AID421747 | Antiallergic activity in mIgE-DNP and DNP-BSA-stimulated rat RBL2H3 cells assessed as inhibition of beta-hexosaminidase release at 100 uM pretreated before mIgE-DNP challenge measured after 24 hrs relative to control | 2009 | Journal of natural products, May-22, Volume: 72, Issue:5
| Antiallergic potential on RBL-2H3 cells of some phenolic constituents of Zingiber officinale (ginger). |
AID1646331 | Inhibition of human recombinant AKR1B1 assessed as D,L-glyceraldehyde reduction at 100 uM incubated in sodium phosphate buffer at pH 6.2 in presence of NADPH relative to control | 2020 | Bioorganic & medicinal chemistry letters, 01-15, Volume: 30, Issue:2
| Early identification of promiscuous attributes of aldose reductase inhibitors using a DMSO-perturbation assay. |
AID1439509 | Antihelmintic activity against Hymenolepis nana | 2017 | European journal of medicinal chemistry, Mar-31, Volume: 129 | Medicinal plants used as anthelmintics: Ethnomedical, pharmacological, and phytochemical studies. |
AID1443033 | Inhibition of recombinant human CYP3A4 expressed in baculosomes using Vivid BOMR substrate red measured every 30 sec for 30 mins by fluorescence assay | 2017 | Bioorganic & medicinal chemistry letters, 04-15, Volume: 27, Issue:8
| Effects of 6-paradol, an unsaturated ketone from gingers, on cytochrome P450-mediated drug metabolism. |
AID1443034 | Inhibition of recombinant human CYP3A4 expressed in baculosomes using Vivid BOMCC substrate blue measured every 30 sec for 30 mins by fluorescence assay | 2017 | Bioorganic & medicinal chemistry letters, 04-15, Volume: 27, Issue:8
| Effects of 6-paradol, an unsaturated ketone from gingers, on cytochrome P450-mediated drug metabolism. |
AID1443026 | Inhibition of CYP2A6 in human liver microsomes using Coumarin as substrate preincubated for 10 mins followed by NADPH addition measured after 15 mins | 2017 | Bioorganic & medicinal chemistry letters, 04-15, Volume: 27, Issue:8
| Effects of 6-paradol, an unsaturated ketone from gingers, on cytochrome P450-mediated drug metabolism. |
AID1219968 | Antioxidant activity assessed as DPPH radical scavenging activity | 2012 | Drug metabolism and disposition: the biological fate of chemicals, Apr, Volume: 40, Issue:4
| Metabolism of [6]-shogaol in mice and in cancer cells. |
AID1443030 | Inhibition of recombinant human CYP2C9 expressed in baculosomes using Vivid OOMR substrate red measured every 30 sec for 30 mins by fluorescence assay | 2017 | Bioorganic & medicinal chemistry letters, 04-15, Volume: 27, Issue:8
| Effects of 6-paradol, an unsaturated ketone from gingers, on cytochrome P450-mediated drug metabolism. |
AID421737 | Cytotoxicity against rat RBL2H3 cells after 12 hrs by MTT assay | 2009 | Journal of natural products, May-22, Volume: 72, Issue:5
| Antiallergic potential on RBL-2H3 cells of some phenolic constituents of Zingiber officinale (ginger). |
AID421749 | Antiallergic activity in mIgE-DNP and DNP-BSA-stimulated rat RBL2H3 cells assessed as inhibition of beta-hexosaminidase release at 200 uM pretreated before mIgE-DNP challenge measured after 24 hrs relative to control | 2009 | Journal of natural products, May-22, Volume: 72, Issue:5
| Antiallergic potential on RBL-2H3 cells of some phenolic constituents of Zingiber officinale (ginger). |
AID1443021 | Inhibition of CYP2B6 in human liver microsomes using bupropion as substrate preincubated for 10 mins followed by NADPH addition measured after 20 mins | 2017 | Bioorganic & medicinal chemistry letters, 04-15, Volume: 27, Issue:8
| Effects of 6-paradol, an unsaturated ketone from gingers, on cytochrome P450-mediated drug metabolism. |
AID1443022 | Inhibition of CYP2C8 in human liver microsomes using amodiaquin as substrate preincubated for 10 mins followed by NADPH addition measured after 10 mins | 2017 | Bioorganic & medicinal chemistry letters, 04-15, Volume: 27, Issue:8
| Effects of 6-paradol, an unsaturated ketone from gingers, on cytochrome P450-mediated drug metabolism. |
AID480938 | Displacement of [3H]8-OH-DPAT from 5HT1A receptor expressed in HEK293 cells at 25 ug/ml after 2 hrs by liquid scintillation counting | 2010 | Bioorganic & medicinal chemistry, May-01, Volume: 18, Issue:9
| Identification of serotonin 5-HT1A receptor partial agonists in ginger. |
AID1646332 | Inhibition of human recombinant AKR1B1 assessed as D,L-glyceraldehyde reduction incubated in sodium phosphate buffer at pH 6.2 in presence of NADPH | 2020 | Bioorganic & medicinal chemistry letters, 01-15, Volume: 30, Issue:2
| Early identification of promiscuous attributes of aldose reductase inhibitors using a DMSO-perturbation assay. |
AID421748 | Antiallergic activity in mIgE-DNP and DNP-BSA-stimulated rat RBL2H3 cells assessed as inhibition of beta-hexosaminidase release at 100 uM pretreated before mIgE-DNP challenge measured after 48 hrs relative to control | 2009 | Journal of natural products, May-22, Volume: 72, Issue:5
| Antiallergic potential on RBL-2H3 cells of some phenolic constituents of Zingiber officinale (ginger). |
AID1443025 | Inhibition of CYP3A4 in human liver microsomes using testosterone as substrate preincubated for 10 mins followed by NADPH addition measured after 10 mins | 2017 | Bioorganic & medicinal chemistry letters, 04-15, Volume: 27, Issue:8
| Effects of 6-paradol, an unsaturated ketone from gingers, on cytochrome P450-mediated drug metabolism. |
AID480937 | Displacement of [3H]8-OH-DPAT from 5HT1A receptor expressed in HEK293 cells after 2 hrs by liquid scintillation counting | 2010 | Bioorganic & medicinal chemistry, May-01, Volume: 18, Issue:9
| Identification of serotonin 5-HT1A receptor partial agonists in ginger. |
AID421745 | Antiallergic activity in mIgE-DNP and DNP-BSA-stimulated rat RBL2H3 cells assessed as inhibition of beta-hexosaminidase release at 1 uM pretreated before mIgE-DNP challenge measured after 24 hrs relative to control | 2009 | Journal of natural products, May-22, Volume: 72, Issue:5
| Antiallergic potential on RBL-2H3 cells of some phenolic constituents of Zingiber officinale (ginger). |
AID421746 | Antiallergic activity in mIgE-DNP and DNP-BSA-stimulated rat RBL2H3 cells assessed as inhibition of beta-hexosaminidase release at 1 uM pretreated before mIgE-DNP challenge measured after 48 hrs relative to control | 2009 | Journal of natural products, May-22, Volume: 72, Issue:5
| Antiallergic potential on RBL-2H3 cells of some phenolic constituents of Zingiber officinale (ginger). |
AID480939 | Agonist activity at 5HT1A receptor expressed in HEK293 cells by [S35]GTPgammaS binding assay relative to 8-OH-DPAT | 2010 | Bioorganic & medicinal chemistry, May-01, Volume: 18, Issue:9
| Identification of serotonin 5-HT1A receptor partial agonists in ginger. |
AID421741 | Antiallergic activity in mIgE-DNP and DNP-BSA-stimulated rat RBL2H3 cells assessed as inhibition of beta-hexosaminidase release at 100 uM pretreated before mIgE-DNP challenge measured after 12 hrs | 2009 | Journal of natural products, May-22, Volume: 72, Issue:5
| Antiallergic potential on RBL-2H3 cells of some phenolic constituents of Zingiber officinale (ginger). |
AID480943 | Permeability in human Caco-2 cells assessed as passive diffusion after 3 hrs by HPLC | 2010 | Bioorganic & medicinal chemistry, May-01, Volume: 18, Issue:9
| Identification of serotonin 5-HT1A receptor partial agonists in ginger. |
AID480944 | Inhibition of human MDR1 expressed in MDCK cells assessed as fluorescence activity at 30 uM after 1.5 hrs by rhodamine 123 efflux test | 2010 | Bioorganic & medicinal chemistry, May-01, Volume: 18, Issue:9
| Identification of serotonin 5-HT1A receptor partial agonists in ginger. |
AID1443032 | Inhibition of recombinant human CYP3A4 expressed in baculosomes using Vivid DBOMF substrate green measured every 30 sec for 30 mins by fluorescence assay | 2017 | Bioorganic & medicinal chemistry letters, 04-15, Volume: 27, Issue:8
| Effects of 6-paradol, an unsaturated ketone from gingers, on cytochrome P450-mediated drug metabolism. |
AID421750 | Antiallergic activity in mIgE-DNP and DNP-BSA-stimulated rat RBL2H3 cells assessed as inhibition of beta-hexosaminidase release at 200 uM pretreated before mIgE-DNP challenge measured after 48 hrs relative to control | 2009 | Journal of natural products, May-22, Volume: 72, Issue:5
| Antiallergic potential on RBL-2H3 cells of some phenolic constituents of Zingiber officinale (ginger). |
AID480942 | Antagonist activity at 5HT1A receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced [S35]GTPgammaS binding by scintillation counting | 2010 | Bioorganic & medicinal chemistry, May-01, Volume: 18, Issue:9
| Identification of serotonin 5-HT1A receptor partial agonists in ginger. |
AID1443031 | Inhibition of recombinant human CYP2C19 expressed in baculosomes using Vivid EOMCC substrate blue measured every 30 sec for 30 mins by fluorescence assay | 2017 | Bioorganic & medicinal chemistry letters, 04-15, Volume: 27, Issue:8
| Effects of 6-paradol, an unsaturated ketone from gingers, on cytochrome P450-mediated drug metabolism. |
AID1443023 | Inhibition of CYP2C9 in human liver microsomes using diclofenac as substrate preincubated for 10 mins followed by NADPH addition measured after 7 mins | 2017 | Bioorganic & medicinal chemistry letters, 04-15, Volume: 27, Issue:8
| Effects of 6-paradol, an unsaturated ketone from gingers, on cytochrome P450-mediated drug metabolism. |
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |