| Assay ID | Title | Year | Journal | Article |
|---|
| AID1345299 | Human Fatty acid amide hydrolase (Hydrolases) | 2007 | Biochemistry, Nov-13, Volume: 46, Issue:45
| Novel mechanistic class of fatty acid amide hydrolase inhibitors with remarkable selectivity. |
| AID1346987 | P-glycoprotein substrates identified in KB-8-5-11 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5
| A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
| AID1296008 | Cytotoxic Profiling of Annotated Libraries Using Quantitative High-Throughput Screening | 2020 | SLAS discovery : advancing life sciences R & D, 01, Volume: 25, Issue:1
| Cytotoxic Profiling of Annotated and Diverse Chemical Libraries Using Quantitative High-Throughput Screening. |
| AID1346986 | P-glycoprotein substrates identified in KB-3-1 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5
| A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
| AID1347160 | Primary screen NINDS Rhodamine qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1347159 | Primary screen GU Rhodamine qHTS for Zika virus inhibitors: Unlinked NS2B-NS3 protease assay | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID690261 | Reversible inhibition of human recombinant FAAH assessed as hydrolysis of [3H]-AEA after 10 mins by liquid scintillation counting | 2011 | Journal of medicinal chemistry, Oct-13, Volume: 54, Issue:19
| SAR and LC/MS studies of β-lactamic inhibitors of human fatty acid amide hydrolase (hFAAH): evidence of a nonhydrolytic process. |
| AID1363886 | Ratio of kinact to Ki for FAAH (unknown origin) | 2017 | Journal of medicinal chemistry, 01-12, Volume: 60, Issue:1
| Therapeutic Potential of Fatty Acid Amide Hydrolase, Monoacylglycerol Lipase, and N-Acylethanolamine Acid Amidase Inhibitors. |
| AID765035 | Inhibition of human recombinant FAAH using N-arachidonyl-7-amino-4-methylcoumarin as substrate preincubated at 500 uM for 20 mins before substrate addition by fluorescence assay | 2013 | Bioorganic & medicinal chemistry, Sep-01, Volume: 21, Issue:17
| Macamides and their synthetic analogs: evaluation of in vitro FAAH inhibition. |
| AID765036 | Inhibition of human recombinant FAAH using N-arachidonyl-7-amino-4-methylcoumarin as substrate preincubated at 10 uM for 20 mins before substrate addition by fluorescence assay | 2013 | Bioorganic & medicinal chemistry, Sep-01, Volume: 21, Issue:17
| Macamides and their synthetic analogs: evaluation of in vitro FAAH inhibition. |
| AID1363885 | Inhibition of recombinant human N-terminal -His6 tagged FAAH (32 to 579 residues) expressed in Escherichia coli BL21-AI preincubated for 5 mins followed by olamide substrate addition measured every 10 sec intervals for 30 mins by spectrophotometry | 2017 | Journal of medicinal chemistry, 01-12, Volume: 60, Issue:1
| Therapeutic Potential of Fatty Acid Amide Hydrolase, Monoacylglycerol Lipase, and N-Acylethanolamine Acid Amidase Inhibitors. |
| AID430491 | Inhibition of FAAH | 2009 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 19, Issue:15
| Fatty acid amide hydrolase inhibitors. Surprising selectivity of chiral azetidine ureas. |
| AID1363884 | Inhibition of recombinant human N-terminal -His6 tagged FAAH (32 to 579 residues) expressed in Escherichia coli BL21 preincubated for 60 mins followed by olamide substrate addition measured every 10 sec intervals for 30 mins by spectrophotometry | 2017 | Journal of medicinal chemistry, 01-12, Volume: 60, Issue:1
| Therapeutic Potential of Fatty Acid Amide Hydrolase, Monoacylglycerol Lipase, and N-Acylethanolamine Acid Amidase Inhibitors. |
| AID726796 | Inhibition of FAAH (unknown origin) | 2013 | Bioorganic & medicinal chemistry, Jan-01, Volume: 21, Issue:1
| Synthesis, SAR study, and biological evaluation of a series of piperazine ureas as fatty acid amide hydrolase (FAAH) inhibitors. |
| AID723532 | Irreversible inhibition of human recombinant FAAH using [3H]AEA as substrate incubated up to 90 mins by compound dilution method | 2013 | European journal of medicinal chemistry, Feb, Volume: 60 | An unprecedented reversible mode of action of β-lactams for the inhibition of human fatty acid amide hydrolase (hFAAH). |
| AID765030 | Irreversible inhibition of human recombinant FAAH using N-arachidonyl-7-amino-4-methylcoumarin as substrate preincubated for 20 mins before substrate addition by fluorescence assay relative to control | 2013 | Bioorganic & medicinal chemistry, Sep-01, Volume: 21, Issue:17
| Macamides and their synthetic analogs: evaluation of in vitro FAAH inhibition. |
| AID765032 | Irreversible inhibition of human recombinant FAAH using N-arachidonyl-7-amino-4-methylcoumarin as substrate preincubated for 20 mins before substrate addition by fluorescence assay | 2013 | Bioorganic & medicinal chemistry, Sep-01, Volume: 21, Issue:17
| Macamides and their synthetic analogs: evaluation of in vitro FAAH inhibition. |
| AID430494 | Potency ratio of Kinact/Ki ratio for human FAAH to Kinact/ki ratio for rat FAAH | 2009 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 19, Issue:15
| Fatty acid amide hydrolase inhibitors. Surprising selectivity of chiral azetidine ureas. |
| AID1798724 | FAAH Inhibition Assay (5 min Preincubation) from Article 10.1021/bi701378g: \\Novel mechanistic class of fatty acid amide hydrolase inhibitors with remarkable selectivity.\\ | 2007 | Biochemistry, Nov-13, Volume: 46, Issue:45
| Novel mechanistic class of fatty acid amide hydrolase inhibitors with remarkable selectivity. |
| AID1798726 | FAAH Inhibition Assay (30 min Preincubation) from Article 10.1021/bi701378g: \\Novel mechanistic class of fatty acid amide hydrolase inhibitors with remarkable selectivity.\\ | 2007 | Biochemistry, Nov-13, Volume: 46, Issue:45
| Novel mechanistic class of fatty acid amide hydrolase inhibitors with remarkable selectivity. |
| AID1798725 | FAAH Inhibition Assay (15 min Preincubation) from Article 10.1021/bi701378g: \\Novel mechanistic class of fatty acid amide hydrolase inhibitors with remarkable selectivity.\\ | 2007 | Biochemistry, Nov-13, Volume: 46, Issue:45
| Novel mechanistic class of fatty acid amide hydrolase inhibitors with remarkable selectivity. |
| AID1798727 | FAAH Inhibition Assay (60 min Preincubation) from Article 10.1021/bi701378g: \\Novel mechanistic class of fatty acid amide hydrolase inhibitors with remarkable selectivity.\\ | 2007 | Biochemistry, Nov-13, Volume: 46, Issue:45
| Novel mechanistic class of fatty acid amide hydrolase inhibitors with remarkable selectivity. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |