Compounds > butinoline
Page last updated: 2024-09-23

butinoline

Cross-References

ID SourceID
PubMed CID68943
CHEMBL ID1442660
CHEBI ID135213
SCHEMBL ID152033

Synonyms (49)

Synonym
EU-0052764
OPREA1_711537
benzenemethanol, alpha-phenyl-alpha-(3-(1-pyrrolidinyl)-1-propynyl)-
butinolinum [inn-latin]
2-butyn-1-ol, 1,1-diphenyl-4-(1-pyrrolidinyl)-
butinoline [inn]
butinolina [inn-spanish]
butinoline
1,1-diphenyl-4-pyrrolidino-1'-yl but-2-yn-1-ol
brn 1388528
1,1-diphenyl-4-(1-pyrrolidinyl)-2-butyn-1-ol
NCGC00160677-01
STK183812
1,1-diphenyl-4-(pyrrolidin-1-yl)but-2-yn-1-ol
OPREA1_030856
MLS000876832
smr000673582
CHEBI:135213
1,1-diphenyl-4-pyrrolidin-1-ylbut-2-yn-1-ol
968-63-8
AKOS000574607
dtxcid1026295
tox21_111980
cas-968-63-8
dtxsid3046295 ,
HMS2966E14
CHEMBL1442660
g216926e9t ,
butinolina
5-20-01-00255 (beilstein handbook reference)
unii-g216926e9t
butinolinum
butinoline [who-dd]
SCHEMBL152033
AB00117777-01
NCGC00160677-02
tox21_111980_1
butinolin
benzenemethanol, .alpha.-phenyl-.alpha.-(3-(1-pyrrolidinyl)-1-propynyl)-
LWPXJPFOEPMIRG-UHFFFAOYSA-N
n-chloroacetyl-dl-2-amino-n-butyricacid
cambridge id 6736893
SR-01000532456-1
sr-01000532456
Q5002527
mfcd00865199
BCP13600
CS-0321601
HY-W276446

Drug Classes (1)

ClassDescription
diarylmethaneAny compound containing two aryl groups connected by a single C atom.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Protein Targets (22)

Potency Measurements

ProteinTaxonomyMeasurementAverage (µ)Min (ref.)Avg (ref.)Max (ref.)Bioassay(s)
Chain A, Beta-lactamaseEscherichia coli K-12Potency63.09570.044717.8581100.0000AID485294
glp-1 receptor, partialHomo sapiens (human)Potency12.58930.01846.806014.1254AID624417
RAR-related orphan receptor gammaMus musculus (house mouse)Potency26.60320.006038.004119,952.5996AID1159521
TDP1 proteinHomo sapiens (human)Potency21.13600.000811.382244.6684AID686978
GLI family zinc finger 3Homo sapiens (human)Potency4.85680.000714.592883.7951AID1259369; AID1259392
estrogen receptor 2 (ER beta)Homo sapiens (human)Potency18.83360.000657.913322,387.1992AID1259378
nuclear receptor subfamily 1, group I, member 3Homo sapiens (human)Potency26.60320.001022.650876.6163AID1224839
cytochrome P450 family 3 subfamily A polypeptide 4Homo sapiens (human)Potency10.67190.01237.983543.2770AID1346984; AID1645841
farnesoid X nuclear receptorHomo sapiens (human)Potency13.33220.375827.485161.6524AID743220
pregnane X nuclear receptorHomo sapiens (human)Potency27.66650.005428.02631,258.9301AID1346982; AID1346985
GVesicular stomatitis virusPotency8.70900.01238.964839.8107AID1645842
cytochrome P450 2D6Homo sapiens (human)Potency12.30180.00108.379861.1304AID1645840
v-jun sarcoma virus 17 oncogene homolog (avian)Homo sapiens (human)Potency17.96300.057821.109761.2679AID1159526; AID1159528
potassium voltage-gated channel subfamily H member 2 isoform dHomo sapiens (human)Potency22.38720.01789.637444.6684AID588834
thyroid hormone receptor beta isoform 2Rattus norvegicus (Norway rat)Potency26.60320.000323.4451159.6830AID743065; AID743067
nuclear receptor ROR-gamma isoform 1Mus musculus (house mouse)Potency0.79430.00798.23321,122.0200AID2551
Interferon betaHomo sapiens (human)Potency8.70900.00339.158239.8107AID1645842
HLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)Potency8.70900.01238.964839.8107AID1645842
Inositol hexakisphosphate kinase 1Homo sapiens (human)Potency8.70900.01238.964839.8107AID1645842
cytochrome P450 2C9, partialHomo sapiens (human)Potency8.70900.01238.964839.8107AID1645842
ATP-dependent phosphofructokinaseTrypanosoma brucei brucei TREU927Potency39.81070.060110.745337.9330AID492961
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Activation Measurements

ProteinTaxonomyMeasurementAverageMin (ref.)Avg (ref.)Max (ref.)Bioassay(s)
short transient receptor potential channel 6 isoform 1Mus musculus (house mouse)EC50 (µMol)3.98000.020020.518970.7900AID2696
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Biological Processes (45)

Processvia Protein(s)Taxonomy
cell surface receptor signaling pathway via JAK-STATInterferon betaHomo sapiens (human)
response to exogenous dsRNAInterferon betaHomo sapiens (human)
B cell activation involved in immune responseInterferon betaHomo sapiens (human)
cell surface receptor signaling pathwayInterferon betaHomo sapiens (human)
cell surface receptor signaling pathway via JAK-STATInterferon betaHomo sapiens (human)
response to virusInterferon betaHomo sapiens (human)
positive regulation of autophagyInterferon betaHomo sapiens (human)
cytokine-mediated signaling pathwayInterferon betaHomo sapiens (human)
natural killer cell activationInterferon betaHomo sapiens (human)
positive regulation of peptidyl-serine phosphorylation of STAT proteinInterferon betaHomo sapiens (human)
cellular response to interferon-betaInterferon betaHomo sapiens (human)
B cell proliferationInterferon betaHomo sapiens (human)
negative regulation of viral genome replicationInterferon betaHomo sapiens (human)
innate immune responseInterferon betaHomo sapiens (human)
positive regulation of innate immune responseInterferon betaHomo sapiens (human)
regulation of MHC class I biosynthetic processInterferon betaHomo sapiens (human)
negative regulation of T cell differentiationInterferon betaHomo sapiens (human)
positive regulation of transcription by RNA polymerase IIInterferon betaHomo sapiens (human)
defense response to virusInterferon betaHomo sapiens (human)
type I interferon-mediated signaling pathwayInterferon betaHomo sapiens (human)
neuron cellular homeostasisInterferon betaHomo sapiens (human)
cellular response to exogenous dsRNAInterferon betaHomo sapiens (human)
cellular response to virusInterferon betaHomo sapiens (human)
negative regulation of Lewy body formationInterferon betaHomo sapiens (human)
negative regulation of T-helper 2 cell cytokine productionInterferon betaHomo sapiens (human)
positive regulation of apoptotic signaling pathwayInterferon betaHomo sapiens (human)
response to exogenous dsRNAInterferon betaHomo sapiens (human)
B cell differentiationInterferon betaHomo sapiens (human)
natural killer cell activation involved in immune responseInterferon betaHomo sapiens (human)
adaptive immune responseInterferon betaHomo sapiens (human)
T cell activation involved in immune responseInterferon betaHomo sapiens (human)
humoral immune responseInterferon betaHomo sapiens (human)
positive regulation of T cell mediated cytotoxicityHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
adaptive immune responseHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independentHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
regulation of T cell anergyHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
defense responseHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
immune responseHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
detection of bacteriumHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
regulation of interleukin-12 productionHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
regulation of interleukin-6 productionHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
protection from natural killer cell mediated cytotoxicityHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
innate immune responseHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
regulation of dendritic cell differentiationHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
antigen processing and presentation of endogenous peptide antigen via MHC class IbHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
inositol phosphate metabolic processInositol hexakisphosphate kinase 1Homo sapiens (human)
phosphatidylinositol phosphate biosynthetic processInositol hexakisphosphate kinase 1Homo sapiens (human)
negative regulation of cold-induced thermogenesisInositol hexakisphosphate kinase 1Homo sapiens (human)
inositol phosphate biosynthetic processInositol hexakisphosphate kinase 1Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Molecular Functions (18)

Processvia Protein(s)Taxonomy
cytokine activityInterferon betaHomo sapiens (human)
cytokine receptor bindingInterferon betaHomo sapiens (human)
type I interferon receptor bindingInterferon betaHomo sapiens (human)
protein bindingInterferon betaHomo sapiens (human)
chloramphenicol O-acetyltransferase activityInterferon betaHomo sapiens (human)
TAP bindingHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
signaling receptor bindingHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
protein bindingHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
peptide antigen bindingHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
TAP bindingHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
protein-folding chaperone bindingHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
inositol-1,3,4,5,6-pentakisphosphate kinase activityInositol hexakisphosphate kinase 1Homo sapiens (human)
inositol hexakisphosphate kinase activityInositol hexakisphosphate kinase 1Homo sapiens (human)
inositol heptakisphosphate kinase activityInositol hexakisphosphate kinase 1Homo sapiens (human)
inositol hexakisphosphate 5-kinase activityInositol hexakisphosphate kinase 1Homo sapiens (human)
protein bindingInositol hexakisphosphate kinase 1Homo sapiens (human)
ATP bindingInositol hexakisphosphate kinase 1Homo sapiens (human)
inositol hexakisphosphate 1-kinase activityInositol hexakisphosphate kinase 1Homo sapiens (human)
inositol hexakisphosphate 3-kinase activityInositol hexakisphosphate kinase 1Homo sapiens (human)
inositol 5-diphosphate pentakisphosphate 5-kinase activityInositol hexakisphosphate kinase 1Homo sapiens (human)
inositol diphosphate tetrakisphosphate kinase activityInositol hexakisphosphate kinase 1Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Ceullar Components (22)

Processvia Protein(s)Taxonomy
extracellular spaceInterferon betaHomo sapiens (human)
extracellular regionInterferon betaHomo sapiens (human)
Golgi membraneHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
endoplasmic reticulumHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
Golgi apparatusHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
plasma membraneHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
cell surfaceHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
ER to Golgi transport vesicle membraneHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
membraneHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
secretory granule membraneHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
phagocytic vesicle membraneHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
early endosome membraneHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
recycling endosome membraneHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
extracellular exosomeHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
lumenal side of endoplasmic reticulum membraneHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
MHC class I protein complexHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
extracellular spaceHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
external side of plasma membraneHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
fibrillar centerInositol hexakisphosphate kinase 1Homo sapiens (human)
nucleoplasmInositol hexakisphosphate kinase 1Homo sapiens (human)
cytosolInositol hexakisphosphate kinase 1Homo sapiens (human)
nucleusInositol hexakisphosphate kinase 1Homo sapiens (human)
cytoplasmInositol hexakisphosphate kinase 1Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Bioassays (48)

Assay IDTitleYearJournalArticle
AID588501High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set2010Current protocols in cytometry, Oct, Volume: Chapter 13Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
AID588501High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set2006Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
Microsphere-based protease assays and screening application for lethal factor and factor Xa.
AID588501High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set2010Assay and drug development technologies, Feb, Volume: 8, Issue:1
High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.
AID504812Inverse Agonists of the Thyroid Stimulating Hormone Receptor: HTS campaign2010Endocrinology, Jul, Volume: 151, Issue:7
A small molecule inverse agonist for the human thyroid-stimulating hormone receptor.
AID1745845Primary qHTS for Inhibitors of ATXN expression
AID588497High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set2010Current protocols in cytometry, Oct, Volume: Chapter 13Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
AID588497High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set2006Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
Microsphere-based protease assays and screening application for lethal factor and factor Xa.
AID588497High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set2010Assay and drug development technologies, Feb, Volume: 8, Issue:1
High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.
AID588499High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set2010Current protocols in cytometry, Oct, Volume: Chapter 13Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
AID588499High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set2006Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
Microsphere-based protease assays and screening application for lethal factor and factor Xa.
AID588499High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set2010Assay and drug development technologies, Feb, Volume: 8, Issue:1
High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.
AID651635Viability Counterscreen for Primary qHTS for Inhibitors of ATXN expression
AID504810Antagonists of the Thyroid Stimulating Hormone Receptor: HTS campaign2010Endocrinology, Jul, Volume: 151, Issue:7
A small molecule inverse agonist for the human thyroid-stimulating hormone receptor.
AID1347103qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for OHS-50 cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347083qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lassa (LASV) Arenavirus: Viability assay - alamar blue signal for LASV Primary Screen2020Antiviral research, 01, Volume: 173A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity.
AID1296008Cytotoxic Profiling of Annotated Libraries Using Quantitative High-Throughput Screening2020SLAS discovery : advancing life sciences R & D, 01, Volume: 25, Issue:1
Cytotoxic Profiling of Annotated and Diverse Chemical Libraries Using Quantitative High-Throughput Screening.
AID1347100qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for LAN-5 cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347099qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for NB1643 cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347154Primary screen GU AMC qHTS for Zika virus inhibitors2020Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
AID1347089qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for TC32 cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347101qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for BT-12 cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347082qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lassa (LASV) Arenavirus: LASV Primary Screen - GLuc reporter signal2020Antiviral research, 01, Volume: 173A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity.
AID1347098qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for SK-N-SH cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347105qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for MG 63 (6-TG R) cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347104qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for RD cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347407qHTS to identify inhibitors of the type 1 interferon - major histocompatibility complex class I in skeletal muscle: primary screen against the NCATS Pharmaceutical Collection2020ACS chemical biology, 07-17, Volume: 15, Issue:7
High-Throughput Screening to Identify Inhibitors of the Type I Interferon-Major Histocompatibility Complex Class I Pathway in Skeletal Muscle.
AID1347091qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for SJ-GBM2 cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1508630Primary qHTS for small molecule stabilizers of the endoplasmic reticulum resident proteome: Secreted ER Calcium Modulated Protein (SERCaMP) assay2021Cell reports, 04-27, Volume: 35, Issue:4
A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome.
AID1347424RapidFire Mass Spectrometry qHTS Assay for Modulators of WT P53-Induced Phosphatase 1 (WIP1)2019The Journal of biological chemistry, 11-15, Volume: 294, Issue:46
Physiologically relevant orthogonal assays for the discovery of small-molecule modulators of WIP1 phosphatase in high-throughput screens.
AID1347102qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for Rh18 cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347094qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for BT-37 cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347093qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for SK-N-MC cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347086qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lymphocytic Choriomeningitis Arenaviruses (LCMV): LCMV Primary Screen - GLuc reporter signal2020Antiviral research, 01, Volume: 173A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity.
AID1347097qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for Saos-2 cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347106qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for control Hh wild type fibroblast cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347096qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for U-2 OS cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347090qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for DAOY cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347107qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for Rh30 cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347108qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for Rh41 cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347095qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for NB-EBc1 cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347425Rhodamine-PBP qHTS Assay for Modulators of WT P53-Induced Phosphatase 1 (WIP1)2019The Journal of biological chemistry, 11-15, Volume: 294, Issue:46
Physiologically relevant orthogonal assays for the discovery of small-molecule modulators of WIP1 phosphatase in high-throughput screens.
AID1347092qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for A673 cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1346986P-glycoprotein substrates identified in KB-3-1 adenocarcinoma cell line, qHTS therapeutic library screen2019Molecular pharmacology, 11, Volume: 96, Issue:5
A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
AID1346987P-glycoprotein substrates identified in KB-8-5-11 adenocarcinoma cell line, qHTS therapeutic library screen2019Molecular pharmacology, 11, Volume: 96, Issue:5
A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
AID504749qHTS profiling for inhibitors of Plasmodium falciparum proliferation2011Science (New York, N.Y.), Aug-05, Volume: 333, Issue:6043
Chemical genomic profiling for antimalarial therapies, response signatures, and molecular targets.
AID1159537qHTS screening for TAG (triacylglycerol) accumulators in algae2017Plant physiology, Aug, Volume: 174, Issue:4
Identification and Metabolite Profiling of Chemical Activators of Lipid Accumulation in Green Algae.
AID1794808Fluorescence-based screening to identify small molecule inhibitors of Plasmodium falciparum apicoplast DNA polymerase (Pf-apPOL).2014Journal of biomolecular screening, Jul, Volume: 19, Issue:6
A High-Throughput Assay to Identify Inhibitors of the Apicoplast DNA Polymerase from Plasmodium falciparum.
AID1794808Fluorescence-based screening to identify small molecule inhibitors of Plasmodium falciparum apicoplast DNA polymerase (Pf-apPOL).
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (17)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (5.88)29.6817
2010's9 (52.94)24.3611
2020's7 (41.18)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other17 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceDescriptionRelationhip StrengthStudiesTrialsClassesRoles
levoplast[no description available]medium10C-nitro compound
hippuric acid[no description available]medium10N-acylglycinehuman blood serum metabolite;
uremic toxin
xanthine[no description available]medium10xanthineSaccharomyces cerevisiae metabolite
atrolactic acid[no description available]medium102-hydroxy monocarboxylic acid
etofylline[no description available]medium10oxopurine
n-acetyltryptophan[no description available]medium10N-acetyl-amino acid;
tryptophan derivative		metabolite
ethacridine[no description available]medium10acridines
altretamine[no description available]medium10triamino-1,3,5-triazine
2,5-di-tert-butylhydroquinone[no description available]medium10hydroquinones
cx546[no description available]medium10
diphenhydramine[no description available]medium10ether;
tertiary amino compound		anti-allergic agent;
antidyskinesia agent;
antiemetic;
antiparkinson drug;
antipruritic drug;
antitussive;
H1-receptor antagonist;
local anaesthetic;
muscarinic antagonist;
oneirogen;
sedative
diuron[no description available]medium103-(3,4-substituted-phenyl)-1,1-dimethylurea;
dichlorobenzene		environmental contaminant;
mitochondrial respiratory-chain inhibitor;
photosystem-II inhibitor;
urea herbicide;
xenobiotic
ibuprofen[no description available]medium10monocarboxylic acidantipyretic;
cyclooxygenase 1 inhibitor;
cyclooxygenase 2 inhibitor;
drug allergen;
environmental contaminant;
geroprotector;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
radical scavenger;
xenobiotic
ipriflavone[no description available]medium10aromatic ether;
isoflavones		bone density conservation agent
mebendazole[no description available]medium10aromatic ketone;
benzimidazoles;
carbamate ester		antinematodal drug;
microtubule-destabilising agent;
tubulin modulator
nocodazole[no description available]medium10aromatic ketone;
benzimidazoles;
carbamate ester;
thiophenes		antimitotic;
antineoplastic agent;
microtubule-destabilising agent;
tubulin modulator
piribedil[no description available]medium10N-arylpiperazine
procainamide[no description available]medium10benzamidesanti-arrhythmia drug;
platelet aggregation inhibitor;
sodium channel blocker
prometone[no description available]medium10diamino-1,3,5-triazine;
methoxy-1,3,5-triazine		environmental contaminant;
herbicide;
xenobiotic
propanil[no description available]medium10anilide;
dichlorobenzene		herbicide
sulfadimethoxine[no description available]medium10aromatic ether;
pyrimidines;
substituted aniline;
sulfonamide antibiotic;
sulfonamide		antiinfective agent;
antimicrobial agent;
drug allergen;
environmental contaminant;
xenobiotic
sulfamethazine[no description available]medium10pyrimidines;
sulfonamide antibiotic;
sulfonamide		antibacterial drug;
antiinfective agent;
antimicrobial agent;
carcinogenic agent;
drug allergen;
EC 2.5.1.15 (dihydropteroate synthase) inhibitor;
environmental contaminant;
ligand;
xenobiotic
sulfathiazole[no description available]medium101,3-thiazoles;
substituted aniline;
sulfonamide antibiotic;
sulfonamide		antiinfective agent;
drug allergen;
EC 2.5.1.15 (dihydropteroate synthase) inhibitor;
environmental contaminant;
xenobiotic
testosterone[no description available]medium103-hydroxy steroidandrogen
2-hydroxybenzylbenzimidazole[no description available]medium10
etimizol[no description available]medium10
nifenalol[no description available]medium10C-nitro compound
bis(4-hydroxyphenyl)sulfone[no description available]medium10bisphenol;
sulfone		endocrine disruptor;
metabolite
8-hydroxyquinoline-5-sulfonic acid[no description available]medium10
salicylanilide[no description available]medium10benzanilide fungicide;
salicylamides;
salicylanilides
2-phenylbutyric acid[no description available]medium10benzenes;
monocarboxylic acid		human xenobiotic metabolite
4,4'-dimethoxybenzophenone[no description available]medium10
6-phenyl-1,3,5-triazine-2,4-diamine[no description available]medium10
quinaldic acid[no description available]medium10quinolinemonocarboxylic acidhuman metabolite;
Saccharomyces cerevisiae metabolite
N-(2-methoxyphenyl)acetamide[no description available]medium10acetamides;
methoxybenzenes
fast red b[no description available]medium10
methylenebis(chloroaniline)[no description available]medium10chloroanilinemetabolite
di-(4-aminophenyl)ether[no description available]medium10aromatic ether
diphenylguanidine[no description available]medium10guanidinesallergen
4-Anilino-4-oxobutanoic acid[no description available]medium10anilide
mephobarbital[no description available]medium10barbituratesanticonvulsant
etryptamine[no description available]medium10indoles
sulfacetamide[no description available]medium10
cinchophen[no description available]medium10quinolines
2-aminobenzothiazole[no description available]medium10benzothiazoles
carzenide[no description available]medium10sulfonamide
nitrilotriacetic acid[no description available]medium10NTA;
tricarboxylic acid		carcinogenic agent;
nephrotoxic agent
n-(2-cyanoethyl)-2-phenylethylamine[no description available]medium10
cyclooctane[no description available]medium10
triphenyltetrazolium chloride[no description available]medium10organic chloride saltdye;
indicator
2,7-diacetylaminofluorene[no description available]medium10
3,4-pyridinedicarboxylic acid[no description available]medium10pyridinedicarboxylic acid
4-(benzoylamino)-2-hydroxybenzoic acid[no description available]medium10benzamides
tropic acid[no description available]medium103-hydroxy monocarboxylic acidhuman xenobiotic metabolite
8-hydroxy-7-iodo-5-quinolinesulfonic acid[no description available]medium10hydroxyquinoline
1-acetylisatin[no description available]medium10indoledione
4-cumylphenol[no description available]medium10diarylmethane
5-methylisatin[no description available]medium10
2-hydrazinobenzothiazole[no description available]medium10
1,2,3-trimethoxybenzene[no description available]medium10methoxybenzenesplant metabolite
2-amino-5-chlorobenzophenone[no description available]medium10
diphenamid[no description available]medium10diarylmethane
4-(4-nitrobenzyl)pyridine[no description available]medium10
5-methyl-3-phenylisoxazole-4-carboxylic acid[no description available]medium10
2-acetylbenzofuran[no description available]medium10
pyrazon[no description available]medium10benzenes;
organochlorine compound;
primary amino compound;
pyridazinone		environmental contaminant;
herbicide;
xenobiotic
2-amino-5-nitrobenzophenone[no description available]medium10
(4-tert-Butyl-phenoxy)-acetic acid[no description available]medium10monocarboxylic acid
lenacil[no description available]medium10cyclopentapyrimidineagrochemical;
environmental contaminant;
herbicide;
xenobiotic
chlordesmethyldiazepam[no description available]medium10benzodiazepine
2-amino-2',5-dichlorobenzophenone[no description available]medium10
2-(2'-hydroxyphenyl)benzimidazole[no description available]medium10
4-phthalimidobutyric acid[no description available]medium10
azabutyrone[no description available]medium10
2-(2-hydroxyphenyl)benzothiazole[no description available]medium10benzothiazoles;
phenols		geroprotector
4,5-dichlorocatechol[no description available]medium10
n-butylbenzenesulfonamide[no description available]medium10sulfonamideneurotoxin;
plant metabolite
3-phenoxybenzoic acid[no description available]medium10phenoxybenzoic acidhuman xenobiotic metabolite;
marine xenobiotic metabolite
2-(2-hydroxyethylmercapto)benzothiazole[no description available]medium10
carboxin[no description available]medium10anilide fungicide;
anilide;
enamide;
organosulfur heterocyclic compound;
oxacycle;
secondary carboxamide		antifungal agrochemical;
EC 1.3.5.1 [succinate dehydrogenase (quinone)] inhibitor
meturin[no description available]medium10
2-bromo-N-phenylbenzamide[no description available]medium10benzamides
4-chlorohippuric acid[no description available]medium10
4-chlorophenoxyacetic acid[no description available]medium10chlorophenoxyacetic acid;
monochlorobenzenes		phenoxy herbicide
2,5-dichloro-1,4-phenylenediamine[no description available]medium10
metribuzin[no description available]medium101,2,4-triazines;
cyclic ketone;
organic sulfide		agrochemical;
environmental contaminant;
herbicide;
xenobiotic
2,5-dimethyl-3-furancarboxanilide[no description available]medium10
moricizine hydrochloride[no description available]medium10hydrochlorideanti-arrhythmia drug
2-benzimidazolylguanidine[no description available]medium10aminoimidazole
diflubenzuron[no description available]medium10benzoylurea insecticide;
monochlorobenzenes		insect sterilant
pentafluorobenzoyl-n-phenylethylamine[no description available]medium10
thidiazuron[no description available]medium10ureas
phenthiazamine[no description available]medium10
5,5-diphenylbarbituric acid[no description available]medium10
3-acetamidobenzoic acid[no description available]medium10
dazoxiben hydrochloride[no description available]medium10
succinylsulfanilamide[no description available]medium10
benzylaminopurine[no description available]medium106-aminopurinescytokinin;
plant metabolite
ciprofloxacin hydrochloride anhydrous[no description available]medium10hydrochlorideantibacterial drug;
antiinfective agent;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
topoisomerase IV inhibitor
src-820 r[no description available]medium10
n(4)-acetylsulfadiazine[no description available]medium10acetamides;
pyrimidines;
sulfonamide		marine xenobiotic metabolite
4-nitro-alpha-acetylamino-beta-hydroxypropiophenone[no description available]medium10
formetamide[no description available]medium10
isbufylline[no description available]medium10
phenylacetylglycine[no description available]medium10monocarboxylic acid amide;
monocarboxylic acid;
N-acylglycine		human metabolite;
mouse metabolite
N-benzoylanthranilic acid[no description available]medium10amidobenzoic acid
n-(2-carboxyphenyl)glycine[no description available]medium10
n,n-dimethyl-4-anisidine[no description available]medium10
n-benzoylpiperidine[no description available]medium10benzamides;
N-acylpiperidine
2-phenylcyclopropanecarboxylic acid[no description available]medium10
n-demethylantipyrine[no description available]medium10pyrazoles;
ring assembly
3-(2-pyridyl)-5,6-diphenyl-1,2,4-triazine[no description available]medium101,2,4-triazines
2-amino-5-bromopyridine[no description available]medium10
n-benzoylalanine, (dl-ala)-isomer[no description available]medium10alanine derivative;
N-acyl-amino acid		metabolite
bicinchoninic acid[no description available]medium10
betamipron[no description available]medium10organonitrogen compound;
organooxygen compound
benzoylpropionic acid[no description available]medium104-oxo monocarboxylic acidhapten
Evoxine[no description available]medium10organic heterotricyclic compound;
organonitrogen heterocyclic compound;
oxacycle
1-methyl-1,2,3,4-tetrahydro-beta-carboline-3-carboxylic acid[no description available]medium10harmala alkaloid
N-Benzylphthalimide[no description available]medium10isoindoles
pyromellitic diimide[no description available]medium10
4'-bromosalicylanilide[no description available]medium10
2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane[no description available]medium10bisphenol
terephthalamide[no description available]medium10benzenedicarboxamide
3(2h)-pyridazinone, 4-chloro-5-(dimethylamino)-2-phenyl-[no description available]medium10
2-nitrophenylacetic acid[no description available]medium10C-nitro compound;
phenylacetic acids
onychine[no description available]medium10
4'-methoxyflavone[no description available]medium10ether;
flavonoids
1,3-diphenyl-2-aminopropane[no description available]medium10
2,2-diphenylpropionic acid[no description available]medium10
3,4-dimethoxyphenylacetamide[no description available]medium10
2-amino-5-bromobenzoic acid[no description available]medium10
2-(1H-benzimidazol-2-yl)aniline[no description available]medium10benzimidazoles;
primary arylamine;
substituted aniline		geroprotector
N-Acetylhomoveratrylamine[no description available]medium10acetamides
2-chlorobenzenesulfonamide[no description available]medium10
4-nitrophenyl dimethylcarbamate[no description available]medium10
8-(4-tolylsulfonylamino)quinoline[no description available]medium10sulfonamide
5-methoxyindole-3-carbaldehyde[no description available]medium10indoles
2-oxo-1,2-dihydroquinoline-4-carboxylic acid[no description available]medium10quinolinemonocarboxylic acid
6-methoxy-2,3,4,9-tetrahydropyrido[3,4-b]indol-1-one[no description available]medium10beta-carbolines
pd 147953[no description available]medium10
fenozan[no description available]medium10
5-phenylbarbituric acid[no description available]medium10
diethylpropion hydrochloride[no description available]medium10hydrochlorideappetite depressant
1-(4'-nitrophenyl)-2-aminopropane-1,3-diol[no description available]medium10
beta-hydroxyphenylalanine[no description available]medium10
3-(n-salicyloyl)amino-1,2,4-triazole[no description available]medium10
7-chloro-4-aminoquinoline[no description available]medium10aminoquinoline
acridine-9-carboxylic acid[no description available]medium10
1-phenazinecarboxylic acid[no description available]medium10aromatic carboxylic acid;
monocarboxylic acid;
phenazines		antifungal agent;
antimicrobial agent;
bacterial metabolite
4,5-diphenyl-1,5-dihydroimidazol-2-one[no description available]medium10stilbenoid
2-hydroxy-1,2-bis(methoxyphenyl)ethanone[no description available]medium10
4-methyl-N-(phenylmethyl)benzenesulfonamide[no description available]medium10sulfonamide
4-n-butylaminobenzoic acid[no description available]medium10aromatic amino acid
fluoren-9-ol[no description available]medium10
1-(2-carboxyethyl)uracil[no description available]medium10
1-benzylindole[no description available]medium10
2,3-bis(2-pyridinyl)quinoxaline[no description available]medium10quinoxaline derivative
3,3',5,5'-tetrachlorobiphenyl-4,4'-diol[no description available]medium10dichlorobenzene;
hydroxybiphenyls
5-nitro-2-(1-piperidinyl)pyridine[no description available]medium10C-nitro compound
2-amino-5,7-dimethyl-1,8-naphthyridine[no description available]medium10
5-benzyloxytryptophan[no description available]medium10
2,5-diethoxy-4-morpholinoaniline[no description available]medium10
3-hydroxy-3-phenacyloxindole[no description available]medium10
carbobenzoxyphenylalanine, (dl-phe)-isomer[no description available]medium10
gamma-fagarine[no description available]medium10organic heterotricyclic compound;
organonitrogen heterocyclic compound;
oxacycle
3-carboxymethyl-6-benzyl-2,5-diketopiperazine[no description available]medium10organonitrogen compound;
organooxygen compound
4-fluorobenzenesulfonamide[no description available]medium10
emoxypine succinate[no description available]medium10
n-carbamyltryptophan[no description available]medium10
2,4,6-trimethoxyacetophenone[no description available]medium10
1-(2-hydroxyethyl)-3,5-diphenyl-1h-pyrazole[no description available]medium10
4-methyoxybenzoyl-n-glycine[no description available]medium10N-acylglycine
5-ethoxy-2-ethylmercaptobenzimidazole[no description available]medium10
5(6)-1(2h)-phthalazinonyl-4(1h)-benzimidazole-2-carbamate methyl ester[no description available]medium10
n-phenyliminodiacetic acid[no description available]medium10
teomorfolin[no description available]medium10
1-(1,3-benzodioxol-5-yl)-3-(1-piperidinyl)-1-propanone[no description available]medium10benzodioxoles
n-(aminocarbonyl)-2-chlorobenzenesulfonamide[no description available]medium10
3-hydroxy-2-quinoxalinepropionic acid[no description available]medium10
8-(methylsulfonylamino)quinoline[no description available]medium10
n(4)-acetylsulfamonomethoxine[no description available]medium10
8-(4-benzenesulfonylamino)quinoline[no description available]medium10
methindione[no description available]medium10
3,4-dihydroxybenzophenone[no description available]medium10
gamma-propanol[no description available]medium10
2-[(3-oxo-1-cyclohexenyl)amino]benzonitrile[no description available]medium10benzenes;
nitrile
isonicotinylamide gaba[no description available]medium10
5-fluorotryptamine monohydrochloride[no description available]medium10
4-iodo-n-(2-(4-morpholinyl)ethyl)benzamide[no description available]medium10
3-(hydroxyacetyl)indole[no description available]medium10indoles
n-(4-aminophenylsulfonyl)morpholine[no description available]medium10
1H-indol-3-yl-(4-methoxyphenyl)methanone[no description available]medium10N-acylindole
2-amino-5-phenyl-1,3,4-thiadiazole[no description available]medium10
N-(1-phenylethyl)acetamide[no description available]medium10acetamides;
secondary carboxamide
alpha-(trichloromethyl)-4-pyridineethanol[no description available]medium10pyridines
ml 204[no description available]medium10
eudesmin[no description available]medium10
2-amino-4-methyl-3-nitropyridine[no description available]medium10
4,4-bis(hydroxymethyl)-2-phenyl-2-oxazoline[no description available]medium10
n-acetylhistidine[no description available]medium10histidine derivative;
N-acetyl-amino acid
1-(1-oxo-2-phenylethyl)-4-piperidinecarboxylic acid[no description available]medium10acetamides
1-(4-chlorophenyl)-3-(2-ethoxyphenyl)urea[no description available]medium10ureas
4-methoxyxanthone[no description available]medium10
N-(4-nitrophenyl)-2-phenoxyacetamide[no description available]medium10C-nitro compound
1-phenylindolin-2-one[no description available]medium10
1-(benzenesulfonyl)indole[no description available]medium10sulfonamide
2,4,4,6-Tetramethyl-1,4-dihydro-3,5-pyridinedicarbonitrile[no description available]medium10dihydropyridine
pifithrin mu[no description available]medium10benzenes
2-benzyloxybenzaldehyde[no description available]medium10
2-guanidine-4-methylquinazoline[no description available]medium10
N-phenylcarbamic acid 2-phenoxyethyl ester[no description available]medium10carbamate ester
3,4-dihydro-2H-benzo[4,5]imidazo[2,1-b][1,3]thiazin-3-ol[no description available]medium10benzimidazoles
mequindox[no description available]medium10
N-[2-(dimethylamino)ethyl]-2,2-diphenylacetamide[no description available]medium10diarylmethane
Girgensonine[no description available]medium10nitrile
Dubinidine[no description available]medium10organic heterotricyclic compound;
organonitrogen heterocyclic compound;
oxacycle
N-[4-(methanesulfonamido)phenyl]acetamide[no description available]medium10sulfonamide
4-(2-oxazolo[4,5-b]pyridinyl)aniline[no description available]medium101,3-oxazoles
2-[(4-nitrophenyl)methylthio]-1,3-benzoxazole[no description available]medium10benzoxazole
3-oxido-4,5-dihydro-[1,2,5]oxadiazolo[3,4-f]cinnolin-3-ium[no description available]medium10pyridazines
3-(2,4-difluoroanilino)-5,5-dimethyl-1-cyclohex-2-enone[no description available]medium10substituted aniline
1-phenyl-4-pyrazolol[no description available]medium10pyrazoles;
ring assembly
3-(3,5-dimethyl-1-pyrazolyl)-1,2-benzothiazole 1,1-dioxide[no description available]medium10benzothiazoles
3-benzamido-2-benzofurancarboxamide[no description available]medium10benzofurans
N-[2-(4-methoxyphenyl)ethyl]acetamide[no description available]medium10acetamides
N-[2-(3-methylphenoxy)ethyl]-1H-1,2,4-triazole-5-carboxamide[no description available]medium10aromatic ether
2-(1H-indol-3-ylthio)acetic acid[no description available]medium10indoles
3-bromo-N-[2-(4-nitroanilino)ethyl]benzamide[no description available]medium10carbonyl compound;
organohalogen compound
3-Methylbenzofuran-2-carboxylic acid[no description available]medium10benzofurans
5-(3,4-dimethoxyphenyl)-2H-tetrazole[no description available]medium10tetrazoles
1-(4-fluorophenyl)sulfonyl-4-(2-methoxyphenyl)piperazine[no description available]medium10piperazines
4-[[bis(2-hydroxyethyl)amino]methyl]-2,6-ditert-butylphenol[no description available]medium10alkylbenzene
2-phenylindole-3-carbaldehyde[no description available]medium10
4-(2-pyridinylthio)benzofuro[3,2-d]pyrimidine[no description available]medium10aryl sulfide
5-(4-nitrophenyl)-4-phenyl-2-thiazolamine[no description available]medium10C-nitro compound
3-[6-(4-aminophenyl)-2-phenyl-4-pyrimidinyl]aniline[no description available]medium10pyrimidines
7-methoxyisoflavone[no description available]medium107-methoxyisoflavones
LSM-32392[no description available]medium10monoterpenoid
N-[2-(1-cyclohexenyl)ethyl]-4-(4-morpholinylmethyl)benzamide[no description available]medium10benzamides
1-(1-benzimidazolyl)-3-(1-cyclohex-3-enylmethoxy)-2-propanol[no description available]medium10benzimidazoles
N-[2-(2-furanylmethylthio)ethyl]-4-methoxybenzenesulfonamide[no description available]medium10sulfonamide
3-acetamido-5-chloro-2-benzofurancarboxylic acid[no description available]medium10benzofurans
[4-(1,3-benzodioxol-5-ylmethyl)-1-piperazinyl]-(2,6-dimethoxyphenyl)methanone[no description available]medium10dimethoxybenzene
4-[4-methyl-6-(4-methyl-1-piperazinyl)-2-pyrimidinyl]morpholine[no description available]medium10N-arylpiperazine
haplamine[no description available]medium10organic heterotricyclic compound;
organonitrogen heterocyclic compound;
oxacycle
5-(3,4-dimethoxyphenyl)-1H-1,2,4-triazol-3-amine[no description available]medium10triazoles
2-ethoxy-N-[4-(4-morpholinylsulfonyl)phenyl]benzamide[no description available]medium10benzamides
2-[(5-methyl-1H-1,2,4-triazol-3-yl)thio]-1-phenylethanone[no description available]medium10aromatic ketone
1-ethyl-6-methoxy-4-oxo-3-quinolinecarboxylic acid[no description available]medium10quinolines
2-(pyridin-4-yl)-4-(pyrrolidin-1-yl)quinazoline[no description available]medium10pyridines;
pyrrolidines;
quinazolines
scp 1[no description available]medium10
N-(3-acetamidophenyl)-4-methoxybenzamide[no description available]medium10benzamides
N-(3-acetamidophenyl)-3-chlorobenzamide[no description available]medium10benzamides
4-methoxy-N-(5-methyl-3-isoxazolyl)benzamide[no description available]medium10benzamides
N-(2-fluorophenyl)-4-phenylmethoxybenzamide[no description available]medium10benzamides
N-[4-(diethylamino)phenyl]-2-furancarboxamide[no description available]medium10aromatic amide;
furans
N-(2-furanylmethyl)-2-benzofurancarboxamide[no description available]medium10benzofurans
5-(2-phenylethyl)-1,3,4-thiadiazol-2-amine[no description available]medium10aromatic amine;
thiadiazoles
te 5[no description available]medium10
2-[[anilino(oxo)methyl]amino]-4,5-dimethyl-3-thiophenecarboxamide[no description available]medium10ureas
N-(4,6-dimethyl-2-pyrimidinyl)-1,3-benzothiazol-2-amine[no description available]medium10benzothiazoles
6-methylflavone[no description available]medium10
2-methoxy-N-(2-pyridinyl)benzamide[no description available]medium10benzamides
2-chloro-N-(2-phenylethyl)benzamide[no description available]medium10carbonyl compound;
organohalogen compound
N1-(4H-1,2,4-triazol-4-yl)-4-nitrobenzamide[no description available]medium10C-nitro compound
N-[2-(1-cyclohexenyl)ethyl]-4-fluorobenzamide[no description available]medium10carbonyl compound;
organohalogen compound
tioxazafen[no description available]medium101,2,4-oxadiazole;
thiophenes		agrochemical;
nematicide
N-[5-(2-methylpropyl)-1,3,4-thiadiazol-2-yl]-2-thiophen-2-ylacetamide[no description available]medium10aromatic amide
1-(4-Methoxyphenyl)-2-nitroethylene[no description available]medium10methoxybenzenes
brd32048[no description available]medium10methoxybenzenes;
substituted aniline
2-(4-chloro-3-methylphenoxy)-N-(1H-1,2,4-triazol-5-yl)acetamide[no description available]medium10aromatic ether
2-(3,4-dichlorophenyl)imidazo[1,2-a]pyrimidine[no description available]medium10imidazoles
5-(2-phenyl-4-triazolyl)-2H-tetrazole[no description available]medium10triazoles
N-cyclohexyl-2,3-dihydroindole-1-carboxamide[no description available]medium10indolyl carboxylic acid
4-(benzylsulfanyl)thieno[2,3-d]pyrimidine[no description available]medium10aryl sulfide;
benzenes;
thienopyrimidine
2-methyl-5-(5-methyl-2-furanyl)-3-(1-pyrrolyl)-4-thieno[2,3-d]pyrimidinone[no description available]medium10organic heterobicyclic compound;
organonitrogen heterocyclic compound;
organosulfur heterocyclic compound
1-[2-(dimethylamino)ethyl]-5-methoxy-N-methyl-2-indolecarboxamide[no description available]medium10indolecarboxamide
N-(5-ethyl-1,3,4-thiadiazol-2-yl)-3-methoxybenzamide[no description available]medium10benzamides
4-(1H-benzimidazol-2-yl)quinoline[no description available]medium10quinolines
1-(4-Chlorophenyl)-2-[(1-methyl-1H-imidazol-2-yl)thio]ethan-1-one[no description available]medium10aromatic ketone
N-(2,5-dimethylphenyl)-2-benzofurancarboxamide[no description available]medium10aromatic amide;
furans
N-(4-methoxyphenyl)-2-benzofurancarboxamide[no description available]medium10aromatic amide;
furans
2-(9h-xanthen-9-yl)-malonic acid[no description available]medium10xanthenes
1-(1,3-benzothiazol-2-yl)-3-phenylurea[no description available]medium10ureas
1-hydroxy-2-phenyl-1,5,6,7-tetrahydro-4H-benzimidazol-4-one[no description available]medium10imidazoles
N-(4-acetamidophenyl)-2-bromobenzamide[no description available]medium10benzamides
4-bromo-N-phenacylbenzamide[no description available]medium10aromatic ketone
1-(2,3-dihydroindol-1-yl)-2-(phenylthio)ethanone[no description available]medium10indoles
N-[6-methyl-2-(4-methylphenyl)-5-benzotriazolyl]-3-pyridinecarboxamide[no description available]medium10triazoles
N,N-dimethyl-N'-p-tolylsulfamide[no description available]medium10sulfamidesmarine xenobiotic metabolite
2-(1-piperidinylmethyl)phenol[no description available]medium10
2,6-bis(benzimidazol-2-yl)pyridine[no description available]medium10benzimidazoles
1-cyclohexyl-3-(2-phenylethyl)urea[no description available]medium10benzenes
1-(3,5-dichlorophenyl)-3-phenylurea[no description available]medium10ureas
1-(cyclohexylmethyl)-4-phenylpiperazine[no description available]medium10piperazines
N-phenethyl-2-furamide[no description available]medium10aromatic amide;
heteroarene
paromomycin sulfate[no description available]medium10
N,N,2-trimethyl-1-phenyl-5-benzimidazolesulfonamide[no description available]medium10benzimidazoles
N-(phenylmethyl)-4-(3-pyridinyl)-2-thiazolamine[no description available]medium10aralkylamine
N-(4-hydroxy-2-methyl-5-propan-2-ylphenyl)benzenesulfonamide[no description available]medium10monoterpenoid
2-amino-5-ethyl-4-(2-furanyl)-6-propyl-3-pyridinecarbonitrile[no description available]medium10nitrile;
pyridines
2-ethoxy-N-[5-(methoxymethyl)-1,3,4-thiadiazol-2-yl]benzamide[no description available]medium10benzamides
vu0099704[no description available]medium10
3-(4-chlorophenyl)-2,5-dimethyl-1H-pyrazolo[1,5-a]pyrimidin-7-one[no description available]medium10pyrazoles;
ring assembly
1-(2-chloro-6-fluorophenyl)-[1,2,4]triazolo[4,3-a]quinoline[no description available]medium10triazoles
2-methyl-N-(1-methyl-2,3-dihydropyrrolo[2,3-b]quinolin-4-yl)propanamide[no description available]medium10pyrroloquinoline
2-methyl-5-[(2-methyl-4-quinolinyl)thio]-1,3,4-thiadiazole[no description available]medium10aryl sulfide
5-methyl-1-(4-nitrophenyl)-2-oxo-2,5-dihydro-1h-pyrido(3,2-b)indole-3-carbonitrile[no description available]medium10
(3-hydroxy-5,6,7,8-tetrahydro-4H-cyclohepta[d]imidazol-2-yl)-phenylmethanone[no description available]medium10aromatic ketone
2-fluoro-N-phenacylbenzamide[no description available]medium10aromatic ketone
4-(methoxymethyl)-6-methyl-2-(2-methylanilino)-3-pyridinecarbonitrile[no description available]medium10nitrile;
pyridines
1-azepanyl-[2-methoxy-4-(methylthio)phenyl]methanone[no description available]medium10carbonyl compound;
thiol
GS4012 free base[no description available]medium10aryl sulfide;
monomethoxybenzene;
pyridines		VEGF activator
N-[1-(4-methylphenyl)-5-benzimidazolyl]acetamide[no description available]medium10benzimidazoles
2-(4-methylanilino)-1-(4-nitrophenyl)ethanone[no description available]medium10aromatic ketone
N-(2,6-dimethylphenyl)-N(2)-(3,5-dimethylphenyl)glycinamide[no description available]medium10amino acid amide;
glycine derivative
2-[4-[(3-fluorophenyl)methyl]-1-piperazinyl]pyrimidine[no description available]medium10N-arylpiperazine
1-[(3,4-dimethoxyphenyl)methyl]-4-(2,3-dimethylphenyl)piperazine[no description available]medium10piperazines
4-Piperidinobenzoic acid[no description available]medium10piperidines
1-(2-methoxyphenyl)-4-(3-thiophenylmethyl)piperazine[no description available]medium10piperazines
N-(1-methyl-2,3-dihydropyrrolo[2,3-b]quinolin-4-yl)-2-(1-pyrrolidinyl)acetamide[no description available]medium10pyrroloquinoline
4-[(1H-benzimidazol-2-ylthio)methyl]-2-thiazolamine[no description available]medium10benzimidazoles
4-[(4-phenyl-2-thiazolyl)amino]benzenesulfonamide[no description available]medium10sulfonamide
N-[7-(1-oxopropyl)-2,3-dihydro-1,4-benzodioxin-6-yl]benzamide[no description available]medium10benzodioxine
N-[3-chloro-4-(1-pyrrolidinyl)phenyl]-2-furancarboxamide[no description available]medium10aromatic amide;
furans
n-(pyridin-2-yl)-4-(pyridin-2-yl)thiazol-2-amine[no description available]medium10
8-(3,5-dimethyl-1-pyrazolyl)quinoline[no description available]medium10quinolines
2'-nitroflavone[no description available]medium10
N-(4-methoxyphenyl)-3,4-dihydroquinolin-2-amine[no description available]medium10aminoquinoline
1-(3-nitrophenyl)-3-phenyl-2-propyn-1-one[no description available]medium10aromatic compound
vrt 532[no description available]medium10
4-[[4-(2,5-dimethylphenyl)-1-piperazinyl]methyl]-2-methoxyphenol[no description available]medium10piperazines
1-piperonylpiperidine[no description available]medium10
2-[(3-fluorophenyl)methyl-(phenylmethyl)amino]ethanol[no description available]medium10aromatic amine
2-methoxy-4-[[2-(methylthio)anilino]methyl]phenol[no description available]medium10aromatic amine
6-ethyl-5-methyl-2-thiophen-2-yl-1H-pyrazolo[1,5-a]pyrimidin-7-one[no description available]medium10pyrazolopyrimidine
N-[4-(2-methyl-4-thiazolyl)phenyl]benzamide[no description available]medium10benzamides
N-(6-phenyl-5-imidazo[2,1-b]thiazolyl)benzamide[no description available]medium10imidazoles
2-(phenylmethylthio)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole[no description available]medium10aryl sulfide
5-methyl-N-(4,5,6-trimethyl-2-pyrimidinyl)-1,3-benzoxazol-2-amine[no description available]medium10benzoxazole
1-(4-methoxyphenyl)-3-(6-methyl-2-pyridinyl)urea[no description available]medium10ureas
2-{[hydroxy(2-methoxyphenyl)methylidene]amino}acetic acid[no description available]medium10N-acylglycine
(4-methoxyphenyl)-(3-methyl-2-propyl-4-imidazolyl)methanone[no description available]medium10aromatic ketone
N-(3-acetamidophenyl)-2-chlorobenzamide[no description available]medium10benzamides
N4,N4-dimethyl-N1-(4-nitro-1,1-dioxo-2,5-dihydrothiophen-3-yl)benzene-1,4-diamine[no description available]medium10dialkylarylamine;
tertiary amino compound
2-bromo-N-(3-methoxyphenyl)benzamide[no description available]medium10benzamides
2-methoxy-4-[(4-methyl-1,4-diazepan-1-yl)methyl]-6-nitrophenol[no description available]medium10aromatic ether;
C-nitro compound
3-[[(2,5-dimethyl-3-furanyl)-oxomethyl]amino]benzoic acid[no description available]medium10aromatic amide;
furans
1-(4-ethoxyphenyl)-3-(6-quinoxalinyl)urea[no description available]medium10quinoxaline derivative
2-(dimethylsulfamoylamino)-9H-fluorene[no description available]medium10fluorenes
4-chloro-1-ethyl-3-nitro-2-quinolinone[no description available]medium10nitro compound;
quinolines
4-chloro-3-nitro-1-(phenylmethyl)-2-quinolinone[no description available]medium10quinolines
2,5-dimethyl-1-(phenylmethyl)pyrrole-3,4-dicarboxaldehyde[no description available]medium10arenecarbaldehyde
2-(2-chloro-6-fluorophenyl)-1-(2,4-dihydroxyphenyl)ethanone[no description available]medium10stilbenoid
4-methyl-N-(3-nitrophenyl)-5-phenyl-3-thiophenecarboxamide[no description available]medium10aromatic amide
N-(5-amino-1-phenyl-1,2,4-triazol-3-yl)-2,2,2-trichloroacetamide[no description available]medium10triazoles
N-(2-fluoro-5-methylphenyl)-3-phenylpropanamide[no description available]medium10anilide
N-[(4-fluorophenyl)methyl]-2-thiophen-2-ylacetamide[no description available]medium10organofluorine compound
4-tert-butyl-N-(1,4-dioxo-2,3-dihydrophthalazin-5-yl)benzamide[no description available]medium10phthalazines
N-[2-(2-methylpropyl)-1,3-dioxo-5-isoindolyl]-2-furancarboxamide[no description available]medium10phthalimides
6-(1,4,5,7-tetramethyl-6-pyrrolo[3,4-d]pyridazinyl)quinoline[no description available]medium10quinolines
2-(3,4-dimethoxyphenyl)-1-(2,4,6-trihydroxyphenyl)ethanone[no description available]medium10stilbenoid
5-(3-chloro-4-methylphenyl)-3-pyridin-4-yl-1,2,4-oxadiazole[no description available]medium10oxadiazole;
ring assembly
5-(phenylmethyl)-3-(2-pyridinyl)-1,2,4-oxadiazole[no description available]medium10pyridines
2-methyl-5-(1-pyrrolidinyl)isoindole-1,3-dione[no description available]medium10phthalimides
(2'-(4-aminophenyl)-(2,5'-bi-1h-benzimidazol)-5-amine)[no description available]medium10benzimidazoles
N-(4-bromo-2-fluorophenyl)-2-methyl-3-furancarboxamide[no description available]medium10aromatic amide;
furans
6,7,8,9-tetrahydro-5H-carbazole-3-carbohydrazide[no description available]medium10carbazoles
N-(3-carbamoyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-2-pyrazinecarboxamide[no description available]medium10primary carboxamide;
pyrazines;
secondary carboxamide
N-(1,3-benzodioxol-5-yl)-5-methyl-2-furancarboxamide[no description available]medium10benzodioxoles
1-cyclohexyl-3-(2,3-dihydro-1,4-benzodioxin-6-yl)urea[no description available]medium10benzodioxine
8-[(2-methyl-5-nitro-1,2,4-triazol-3-yl)thio]quinoline[no description available]medium10aryl sulfide
1-[2-(2-chlorophenoxy)ethyl]benzimidazole[no description available]medium10benzimidazoles
4,5-dimethyl-2-[4-(3-nitrophenyl)-2-thiazolyl]-1H-pyrazol-3-one[no description available]medium10C-nitro compound
2-(4-fluoro-N-methylsulfonylanilino)-N-(3-methylphenyl)acetamide[no description available]medium10sulfonamide
1-(4-fluorophenyl)-2-(2-pyridinylthio)ethanone[no description available]medium10aromatic ketone
3-methyl-6-(1-pyrrolidinyl)-[1,2,4]triazolo[4,3-b]pyridazine[no description available]medium10triazolopyridazine
N-(3-acetylphenyl)-2-thiophen-2-ylacetamide[no description available]medium10aromatic ketone
oncrasin-1[no description available]medium10arenecarbaldehyde;
indoles;
monochlorobenzenes		antineoplastic agent;
apoptosis inducer
N-[2-(4-fluorophenyl)ethyl]-4-nitrobenzamide[no description available]medium10C-nitro compound
5-(1-methyl-2-benzimidazolyl)-2-thiophenecarboxaldehyde[no description available]medium10benzimidazoles
N-(4-anilinophenyl)-2-methylpropanamide[no description available]medium10anilide
N-(2-fluorophenyl)-3-phenylpropanamide[no description available]medium10anilide
1-[(Phenylthio)acetyl]piperidine[no description available]medium10N-acylpiperidine
N-(3-hydroxyphenyl)-5-methyl-3-furancarboxamide[no description available]medium10aromatic amide;
furans
3-(4-methoxyphenyl)-5-(4-methylphenyl)-1,2,4-oxadiazole[no description available]medium10oxadiazole;
ring assembly
4-[(4-carboxy-2,6-dimethoxyphenoxy)methyl]-5-methyl-2-furancarboxylic acid[no description available]medium10trihydroxybenzoic acid
4-(4-morpholinylmethyl)-3-quinolinol[no description available]medium10quinolines
2-bromo-N-[3-(1-oxopropylamino)phenyl]benzamide[no description available]medium10benzamides
3-acetyl-2-methylbenzo[f]benzofuran-4,9-dione[no description available]medium10naphthofuran
5-(4-chlorophenyl)-N-(5-ethyl-1,3,4-thiadiazol-2-yl)-2-furancarboxamide[no description available]medium10aromatic amide;
heteroarene
1-azepanyl-[4-[(phenylthio)methyl]phenyl]methanone[no description available]medium10benzamides
1-(5-ethyl-2,4-dihydroxyphenyl)-2-(2-fluorophenoxy)ethanone[no description available]medium10aromatic ketone
N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-(2-nitrophenyl)acetamide[no description available]medium10acetamides
3,4,5-triethoxy-N-(1H-1,2,4-triazol-5-yl)benzamide[no description available]medium10benzamides
1-propylsulfonyl-4-(2-pyridinyl)piperazine[no description available]medium10piperazines;
pyridines
2-(2-phenylethylthio)-3-pyridinecarboxylic acid[no description available]medium10aromatic carboxylic acid;
pyridines
2-(2,3-dimethylphenoxy)-N-pyridin-4-ylacetamide[no description available]medium10aromatic ether
2-[[anilino(oxo)methyl]amino]-N-(phenylmethyl)benzamide[no description available]medium10benzamides
N-(5-acetyl-4-methyl-2-thiazolyl)-5-bromo-2-furancarboxamide[no description available]medium10thiazoles
1-cyclohexyl-3-(3-ethylphenyl)urea[no description available]medium10ureas
n-phenylpiracetam[no description available]medium10
2-[(1-methyl-5-tetrazolyl)thio]-N-(2-phenylphenyl)acetamide[no description available]medium10biphenyls
N-[3-chloro-4-(1-pyrrolidinyl)phenyl]-2-nitrobenzamide[no description available]medium10benzamides
4-(3,4-dihydro-1H-isoquinolin-2-ylmethyl)-N-(2,6-dimethylphenyl)benzamide[no description available]medium10isoquinolines
5-(4-bromophenyl)-N-(2-methoxyphenyl)-2-furancarboxamide[no description available]medium10aromatic amide;
furans
3-[[(3,5-dichloro-4-ethoxyphenyl)-oxomethyl]amino]benzoic acid[no description available]medium10benzamides
1,4-bis(thiophen-2-ylsulfonyl)piperazine[no description available]medium10N-sulfonylpiperazine;
thiophenes
2-bromo-N-[3-(1-oxobutylamino)phenyl]benzamide[no description available]medium10benzamides
1-(2-fluorophenyl)-4-[(6-nitro-1,3-benzodioxol-5-yl)methyl]piperazine[no description available]medium10piperazines
n-(1-benzyl-4-piperidinyl)-2,4-dichlorobenzamide[no description available]medium10
2-[[2-(5-methyl-2-thiophenyl)-2-oxoethyl]thio]-3-phenyl-4-quinazolinone[no description available]medium10quinazolines
1-(2,1,3-benzothiadiazol-5-yl)-3-[4-(4-morpholinyl)phenyl]urea[no description available]medium10morpholines
ethyl 4-{N-[(4-chlorophenyl)sulfonyl]-N-methylglycyl}piperazine-1-carboxylate[no description available]medium10carbamate ester;
sulfonamide
LSM-4563[no description available]medium10aromatic ketone
1-(4-chloro-3-methoxyphenyl)sulfonyl-4-phenylpiperazine[no description available]medium10piperazines
N-[4-[(3,4-dimethoxyphenyl)sulfamoyl]phenyl]acetamide[no description available]medium10sulfonamide
4-chloro-3-(1-piperidinylsulfonyl)-N-(2-thiazolyl)benzamide[no description available]medium10sulfonamide
1-(2,5-dimethoxyphenyl)sulfonyl-4-(phenylmethyl)piperazine[no description available]medium10sulfonamide
2-(4-methoxyphenyl)-N-[4-[(5-methyl-3-isoxazolyl)sulfamoyl]phenyl]acetamide[no description available]medium10sulfonamide
4-[4-(benzenesulfonyl)-1-piperazinyl]-2-methylquinoline[no description available]medium10piperazines;
pyridines
1-(6-methoxy-2,2,4-trimethyl-1-quinolinyl)-2-[[5-(4-methylphenyl)-1,3,4-oxadiazol-2-yl]thio]ethanone[no description available]medium10quinolines
N2-phenyl-6-[[(1-phenyl-5-tetrazolyl)thio]methyl]-1,3,5-triazine-2,4-diamine[no description available]medium10tetrazoles
2-[(4,6-dimethyl-2-pyrimidinyl)thio]-N-(4,5-diphenyl-2-oxazolyl)acetamide[no description available]medium101,3-oxazoles
2-(4-bromophenyl)-1-[4-(2-pyridinyl)-1-piperazinyl]ethanone[no description available]medium10piperazines;
pyridines
2-amino[1,3]thiazolo[4,5-d]pyrimidine-5,7-diol[no description available]medium10thiazolopyrimidine
3-[[(2-cyclohexyl-1,3-dioxo-5-isoindolyl)-oxomethyl]amino]benzoic acid[no description available]medium10aromatic amide
3-[[[3-(1-azepanylsulfonyl)-4-chlorophenyl]-oxomethyl]amino]benzoic acid[no description available]medium10benzamides
2-(4-bromophenyl)-N-(5-tert-butyl-1,3,4-thiadiazol-2-yl)acetamide[no description available]medium10acetamides
5-(1,3-benzodioxol-5-ylsulfamoyl)-2-methoxybenzoic acid[no description available]medium10methoxybenzoic acid
N-cycloheptyl-1-(4-methylphenyl)sulfonyl-4-piperidinecarboxamide[no description available]medium10sulfonamide
3-(2-chlorophenyl)-5-methyl-N-[4-[2-(4-morpholinyl)-2-oxoethoxy]phenyl]-4-isoxazolecarboxamide[no description available]medium10aromatic amide
N-[3-[[(4-nitrophenyl)-oxomethyl]amino]phenyl]-2-furancarboxamide[no description available]medium10benzamides
3-methyl-1,5-dithiophen-2-ylpentane-1,5-dione[no description available]medium10aromatic ketone
N-(2-methyl-1,3-benzothiazol-6-yl)-4-(4-morpholinylsulfonyl)benzamide[no description available]medium10sulfonamide
4-(dimethylsulfamoyl)-N-(4-thiophen-2-yl-2-thiazolyl)benzamide[no description available]medium10sulfonamide
3-chloro-N-[4-[(1-oxo-2-phenylethyl)amino]phenyl]benzamide[no description available]medium10benzamides
N-(3,4-dimethoxyphenyl)-4-[(4-phenyl-1-piperazinyl)methyl]benzamide[no description available]medium10benzamides
stk295900[no description available]medium10
1-(3-chlorophenyl)-4-[(3,4,5-trimethoxyphenyl)methyl]piperazine[no description available]medium10piperazines
2-[4-[[4-(4-methoxyphenyl)-1-phthalazinyl]amino]phenyl]acetamide[no description available]medium10pyridazines;
ring assembly
1-(2-fluorophenyl)-3-[5-(2-fluorophenyl)-1,3,4-thiadiazol-2-yl]urea[no description available]medium10ureas
N-[5-[(4-methoxyphenyl)methyl]-1,3,4-thiadiazol-2-yl]-2-furancarboxamide[no description available]medium10methoxybenzenes
N-(1,3-benzodioxol-5-yl)-4-methyl-1-phthalazinamine[no description available]medium10phthalazines
SMER 28[no description available]medium10organobromine compound;
quinazolines;
secondary amino compound		autophagy inducer
N-[4-(4-morpholinyl)phenyl]carbamic acid butyl ester[no description available]medium10morpholines
4-(4-chlorophenoxy)-1-(4-morpholinyl)-1-butanone[no description available]medium10aromatic ether
4-(4-chlorophenoxy)-1-(1-piperidinyl)-1-butanone[no description available]medium10N-acylpiperidine
N-(3-phenylpropyl)methanesulfonamide[no description available]medium10benzenes
4-acetamido-N-(2-methoxyethyl)benzamide[no description available]medium10amidobenzoic acid
2-methyl-N-(2,3,4,5,6-pentafluorophenyl)-3-furancarboxamide[no description available]medium10aromatic amide;
furans
3,4-dihydro-2H-quinolin-1-yl-(4-propoxyphenyl)methanone[no description available]medium10quinolines
5-bromo-N-(2-phenylphenyl)-2-furancarboxamide[no description available]medium10aromatic amide;
furans
2-[2-(4-chlorophenoxy)ethylthio]pyrimidine[no description available]medium10aromatic ether
3-(3-bromoanilino)-1-(5-methyl-2-furanyl)-1-propanone[no description available]medium10aralkylamine
4-[2-(4-bromo-2-chlorophenoxy)-1-oxoethyl]-1-piperazinecarboxylic acid ethyl ester[no description available]medium10piperazinecarboxylic acid
2-[2-[[3-(1,3-benzoxazol-2-yl)anilino]-oxomethyl]phenyl]benzoic acid[no description available]medium10benzamides
1-[2-(2-chlorophenoxy)ethoxy]-2-methoxy-4-methylbenzene[no description available]medium10methoxybenzenes
N-[4-[(4-sulfamoylphenyl)sulfamoyl]phenyl]cyclopropanecarboxamide[no description available]medium10sulfonamide
4-[2-[2-(4-bromo-2-chlorophenoxy)ethoxy]ethyl]morpholine[no description available]medium10aromatic ether
N-[2-(2-phenylphenoxy)ethyl]-2-furancarboxamide[no description available]medium10biphenyls
5,6,7,8-tetrafluoro-2-(2,3,4,5,6-pentafluorophenyl)-4h-1-benzopyran-4-one[no description available]medium10
2-[bis(5-methyl-2-furanyl)methyl]-6-nitrophenol[no description available]medium10nitrophenol
2-(4-nitrophenyl)-N-(2-oxolanylmethyl)-4-quinazolinamine[no description available]medium10quinazolines
2-(4-hydroxy-1,3-thiazol-2-yl)-1-phenylethan-1-one[no description available]medium10aromatic ketone
Methyl(2-furoylamino)acetic acid[no description available]medium10N-acyl-amino acid
5-nitro-8-(1-pyrrolidinyl)quinoline[no description available]medium10nitro compound;
quinolines
2-(3-oxo-2,4-dihydro-1H-quinoxalin-2-yl)-N-phenylacetamide[no description available]medium10amino acid amide
2-[(4-methylphenyl)sulfonylamino]pentanoic acid[no description available]medium10sulfonamide
4,6-dimorpholino-n-(4-nitrophenyl)-1,3,5-triazin-2-amine[no description available]medium10
1-[(3-chlorophenyl)methyl]-N,N-diethyl-3-piperidinecarboxamide[no description available]medium10piperidines
1-(2,6-dimethyl-1-piperidinyl)-2-phenylethanone[no description available]medium10acetamides
2-amino-7-methyl-5-oxo-4-(2,3,4-trimethoxyphenyl)-4,6,7,8-tetrahydro-1-benzopyran-3-carbonitrile[no description available]medium10methoxybenzenes
3-[4-(1,3-benzodioxol-5-ylmethyl)-1-piperazinyl]-1-phenylpyrrolidine-2,5-dione[no description available]medium10pyrrolidines
1-(4-bromophenyl)-3-(diethylamino)pyrrolidine-2,5-dione[no description available]medium10pyrrolidines
4-(5,6-diphenyl-1,2,4-triazin-3-yl)morpholine[no description available]medium10dialkylarylamine;
tertiary amino compound
(3,5-Dimethyl-1-adamantyl)amine nitrate[no description available]medium10nitrates
1-(4-tert-butylphenoxy)-3-(1H-1,2,4-triazol-5-ylthio)-2-propanol[no description available]medium10alkylbenzene
N-[2-(1-methyl-2-pyrrolidinyl)ethyl]-2-adamantanamine[no description available]medium10N-alkylpyrrolidine
4-phenyl-N-(pyridin-4-ylmethyl)-2-butanamine[no description available]medium10aralkylamine
N-(5-nitro-2-pyridinyl)cyclopropanecarboxamide[no description available]medium10aromatic amide
3-[(4-bromophenyl)methyl]-4-(4-methoxyanilino)-4-oxobutanoic acid[no description available]medium10anilide
3-ethyl-N-(2H-tetrazol-5-yl)-1-adamantanecarboxamide[no description available]medium10aromatic amide
N-(4-propan-2-ylphenyl)-3-bicyclo[2.2.1]heptanecarboxamide[no description available]medium10monoterpenoid
4-chloro-N-[2-(4-nitroanilino)ethyl]benzamide[no description available]medium10carbonyl compound;
organohalogen compound
2-[(2,3-dihydro-1,4-benzodioxin-6-ylamino)-oxomethyl]-1-cyclohexanecarboxylic acid[no description available]medium10benzodioxine
2,4-dichloro-6-[1-(4-morpholinyl)-3-phenylprop-2-ynyl]phenol[no description available]medium10aromatic compound
2-[[1-(4-ethoxyphenyl)-2,5-dioxo-3-pyrrolidinyl]amino]acetonitrile[no description available]medium10pyrrolidines
1-ethoxy-3-(2-methoxy-4-prop-2-enylphenoxy)-2-propanol[no description available]medium10methoxybenzenes
6-amino-4-(3-chlorophenyl)-3-methyl-1-(phenylmethyl)-4H-pyrano[2,3-c]pyrazole-5-carbonitrile[no description available]medium10organochlorine compound;
pyranopyrazole
1-(2-chlorophenoxy)-3-(2-methyl-1-benzimidazolyl)-2-propanol[no description available]medium10benzimidazoles
N-[2-furanyl-(8-hydroxy-7-quinolinyl)methyl]-2-methylpropanamide[no description available]medium10hydroxyquinoline
N-(2-hydroxy-5-methylphenyl)-2-furancarboxamide[no description available]medium10aromatic amide;
furans
4-amino-7,8,9,10-tetrahydro-6H-pyrimido[3,4]pyrrolo[3,5-a]azepine-11-carbonitrile[no description available]medium10organic heterobicyclic compound;
organonitrogen heterocyclic compound
1-(3,5-dimethylphenyl)-3-(1H-1,2,4-triazol-5-ylthio)pyrrolidine-2,5-dione[no description available]medium10pyrrolidines
6-[(3,4-difluoroanilino)-oxomethyl]-1-cyclohex-3-enecarboxylic acid[no description available]medium10anilide
4-[(3-cyano-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophen-2-yl)amino]-4-oxobutanoic acid[no description available]medium10organosulfur heterocyclic compound
[3-methyl-4-[oxo(thiophen-2-yl)methyl]-1-piperazinyl]-thiophen-2-ylmethanone[no description available]medium10aromatic amide;
thiophenes
[4-(2-methoxyphenyl)-1-piperazinyl]-[4-[(phenylthio)methyl]phenyl]methanone[no description available]medium10piperazines
N-(3,3,5-trimethylcyclohexyl)-1H-1,2,4-triazole-5-carboxamide[no description available]medium10aromatic amide;
heteroarene
4-[2-nitro-5-[4-(phenylmethyl)sulfonyl-1-piperazinyl]phenyl]morpholine[no description available]medium10piperazines
5-(4-ethylsulfonyl-1-piperazinyl)-2-nitro-N-(3-pyridinylmethyl)aniline[no description available]medium10piperazines
2-[[5-[(1,3-benzothiazol-2-ylthio)methyl]-4-methyl-1,2,4-triazol-3-yl]thio]-N-[2-(4-morpholinyl)ethyl]acetamide[no description available]medium10benzothiazoles
N-ethyl-N-[2-[(5-nitro-8-quinolinyl)amino]ethyl]benzenesulfonamide[no description available]medium10nitro compound;
quinolines
1-(4-methoxyphenyl)-N-(4-methyl-2-pyridinyl)-5-oxo-3-pyrrolidinecarboxamide[no description available]medium10pyrrolidines
3,4,5-trimethoxy-N-[4-[(2-methyl-1-piperidinyl)sulfonyl]phenyl]benzamide[no description available]medium10benzamides
3-(n,n-dimethylsulfonamido)-4-methyl-nitrobenzene[no description available]medium10C-nitro compound;
sulfonamide;
toluenes		bone density conservation agent;
EC 3.1.4.53 (3',5'-cyclic-AMP phosphodiesterase) inhibitor;
geroprotector
6,3',4'-Trimethoxyflavanone[no description available]medium10ether;
flavonoids
1-[4-(3-ethoxyphenoxy)butyl]imidazole[no description available]medium10aromatic ether
5-[[(1-cyclohexyl-5-tetrazolyl)thio]methyl]-3-phenyl-1,2,4-oxadiazole[no description available]medium10oxadiazole;
ring assembly
2-[1-(3,4-dihydro-2H-quinolin-1-yl)-1-oxopropan-2-yl]isoindole-1,3-dione[no description available]medium10phthalimides
[4-(benzenesulfonyl)-1-piperazinyl]-(1-piperidinyl)methanone[no description available]medium10sulfonamide
3-(2,5-dioxo-1-pyrrolidinyl)-N-(2-methyl-1,3-dioxo-5-isoindolyl)benzamide[no description available]medium10amidobenzoic acid
6-[[[5-(ethylthio)-1,3,4-thiadiazol-2-yl]amino]-oxomethyl]-1-cyclohex-3-enecarboxylic acid[no description available]medium10aromatic amide
2,5-dimethoxy-n-(quinolin-3-yl)benzenesulfonamide[no description available]medium10quinolines
LSM-25805[no description available]medium10isoindoles
4-ethoxy-N-(3-quinolinyl)benzenesulfonamide[no description available]medium10quinolines
3-chloro-N-[3-(1-imidazolyl)propyl]-6-nitro-1-benzothiophene-2-carboxamide[no description available]medium101-benzothiophenes
nsc 727447[no description available]medium10
2-methoxy-N-[(4-methylphenyl)methyl]-2-phenylacetamide[no description available]medium10acetamides
2-(4-chlorophenoxy)-N-(5-nitro-2-thiazolyl)acetamide[no description available]medium10C-nitro compound;
thiazoles
7-(2-methoxyphenyl)-5-phenyl-1,7-dihydrotetrazolo[1,5-a]pyrimidine[no description available]medium10methoxybenzenes
N-[3-[2,5-dioxo-3-(phenylmethyl)-1-pyrrolidinyl]phenyl]acetamide[no description available]medium10pyrrolidines
3,4-dimethoxy-N-[3-(methylthio)phenyl]benzenesulfonamide[no description available]medium10sulfonamide
3-methyl-4-nitro-N-(1H-1,2,4-triazol-5-yl)benzamide[no description available]medium10C-nitro compound
2-[(4-chlorophenyl)methylthio]-N-(2-hydroxy-5-nitrophenyl)acetamide[no description available]medium10nitrophenol
2-(4-ethoxyphenyl)-N-[3-(1-imidazolyl)propyl]-4-quinolinecarboxamide[no description available]medium10quinolines
N-(4-bromophenyl)-5-methyl-4-nitro-1H-pyrazol-3-amine[no description available]medium10C-nitro compound
3,3-bis(4-hydroxyphenyl)-7-methyl-1,3-dihydro-2h-indol-2-one[no description available]medium10
N-[4-[(cyclohexylamino)-oxomethyl]phenyl]-3-pyridinecarboxamide[no description available]medium10aromatic amide
N,N,4-trimethyl-2-[[(5-methyl-2-furanyl)-oxomethyl]amino]-5-thiazolecarboxamide[no description available]medium10aromatic amide;
thiazoles
ex 527[no description available]medium10carbazoles;
monocarboxylic acid amide;
organochlorine compound
3-[3-[(5-ethyl-[1,2,4]triazino[5,6-b]indol-3-yl)thio]propyl]-1H-benzimidazol-2-one[no description available]medium10indoles
4-methyl-2,7-diphenyl-8H-pyrido[2,3-d]pyrimidin-5-one[no description available]medium10phenylpyridine
3-methylharman[no description available]medium10
1-methyl-beta-carboline-3-carboxylic acid[no description available]medium10
sildenafil[no description available]medium10piperazines;
pyrazolopyrimidine;
sulfonamide		EC 3.1.4.35 (3',5'-cyclic-GMP phosphodiesterase) inhibitor;
vasodilator agent
2-methyl-4(3h)-quinazolinone[no description available]medium10
n(4)-desoxychlordiazepoxide[no description available]medium10
2-amino-3-hydroxyphenazine[no description available]medium10
2-styrylquinazolin-4(3h)-one[no description available]medium10
2-amino-5-iodo-6-phenyl-4-pyrimidinone[no description available]medium10
quininib[no description available]medium10phenols;
styrylquinoline		angiogenesis inhibitor
bropirimine[no description available]medium10pyrimidines
2-[(6-ethyl-4-methyl-2-quinazolinyl)amino]-1H-quinazolin-4-one[no description available]medium10quinazolines
2-[(6-ethyl-4-methyl-2-quinazolinyl)amino]-6-(methoxymethyl)-1H-pyrimidin-4-one[no description available]medium10quinazolines
b 844-39[no description available]low00diarylmethane
3-[(4-chlorophenyl)-phenylmethoxy]-8-methyl-8-azabicyclo[3.2.1]octane[no description available]low00diarylmethane
adiphenine[no description available]low00diarylmethane
3-(2'-aminobenzhydryloxy)tropane[no description available]low00diarylmethane
2,2-bis(4-glycidyloxyphenyl)propane[no description available]low00diarylmethane
benproperine[no description available]low00diarylmethane
cogentin[no description available]low00diarylmethane
bifemelane[no description available]low00diarylmethane
bisacodyl[no description available]low00diarylmethane
chlorcyclizine[no description available]low00diarylmethane
cifenline[no description available]low00diarylmethane
clidinium[no description available]low00diarylmethane
clofedanol[no description available]low00diarylmethane;
tertiary amino compound		antitussive
clofoctol[no description available]low00diarylmethane
cloperastine[no description available]low00diarylmethane
r 59022[no description available]low00diarylmethane
dichlorophen[no description available]low00bridged diphenyl fungicide;
diarylmethane
fendiline[no description available]low00diarylmethane
1-[bis(4-fluorophenyl)methyl]-4-(3-phenylprop-2-enyl)piperazine[no description available]low00diarylmethane
fluspirilene[no description available]low00diarylmethane
homochlorocyclizine[no description available]low00diarylmethane
isopropamide iodide[no description available]low00diarylmethane
lidoflazine[no description available]low00diarylmethane
lomerizine[no description available]low00diarylmethane
manidipine[no description available]low00diarylmethane
meclizine[no description available]low00diarylmethane
mepenzolate[no description available]low00diarylmethane
methadone[no description available]low00benzenes;
diarylmethane;
ketone;
tertiary amino compound
mitotane[no description available]low00diarylmethane
no 711[no description available]low00diarylmethane
oxatomide[no description available]low00benzimidazoles;
diarylmethane;
N-alkylpiperazine		anti-allergic agent;
anti-inflammatory agent;
geroprotector;
H1-receptor antagonist;
serotonergic antagonist
pipenzolate[no description available]low00diarylmethane
piperidolate[no description available]low00diarylmethane
proadifen[no description available]low00diarylmethane
propiverine[no description available]low00diarylmethane
aurin[no description available]low00diarylmethane
dpi 201-106[no description available]low00diarylmethane
terfenadine[no description available]low00diarylmethane
mepenzolate bromide[no description available]low00diarylmethane
chlorphenoxamine[no description available]low00diarylmethaneanticoronaviral agent
chlorfenethol[no description available]low00diarylmethane
diphenadione[no description available]low00beta-triketone;
diarylmethane
phenyltoloxamine[no description available]low00diarylmethane
n,n,n',n'-tetramethyl-4,4'-methylenedianiline[no description available]low00diarylmethane
diphenan[no description available]low00diarylmethane
diphenylmethane[no description available]low00diarylmethane
2,2'-methylenebis(4-methyl-6-tert-butylphenol)[no description available]low00diarylmethane
piperidolate hydrochloride[no description available]low00diarylmethane
benactyzine[no description available]low00diarylmethane
prenylamine[no description available]low00diarylmethane
isomethadone[no description available]low00diarylmethane
pipradrol[no description available]low00diarylmethane
normethadone[no description available]low00diarylmethane
captodiamine[no description available]low00diarylmethane
methadyl acetate[no description available]low00diarylmethane
benzomethamine[no description available]low00diarylmethane
chlorobenzilate[no description available]low00diarylmethane
dimenhydrinate[no description available]low00diarylmethane
poldine[no description available]low00diarylmethane
thiphenamil[no description available]low00diarylmethane
4,4'-bisphenol f[no description available]low00bisphenol;
diarylmethane		environmental food contaminant;
xenoestrogen
o,p'-ddt[no description available]low00diarylmethane
4,4'-methylene bis(2-methylaniline)[no description available]low00diarylmethane
dipipanone[no description available]low00diarylmethane
paracymethadol[no description available]low00diarylmethane
bisphenol a-glycidyl methacrylate[no description available]low00diarylmethane
azacyclonol[no description available]low00diarylmethane
dimenoxadol[no description available]low00diarylmethane
amphenone b[no description available]low00diarylmethane
propinox[no description available]low00diarylmethane
embramine[no description available]low00diarylmethane
chlorophacinone[no description available]low00beta-triketone;
diarylmethane
aminopentamide[no description available]low00diarylmethane
octocrylene[no description available]low00diarylmethane
terodiline[no description available]low00diarylmethane
tofenacin[no description available]low00diarylmethane
pipoxolan[no description available]low00diarylmethane
penfluridol[no description available]low00diarylmethane
emepronium[no description available]low00diarylmethane
levomethadyl acetate hydrochloride[no description available]low00diarylmethane
flumecinol[no description available]low00diarylmethane
setastine[no description available]low00diarylmethane
progabide[no description available]low00diarylmethane
beclobrate[no description available]low00diarylmethane
cetirizine dihydrochloride[no description available]low00diarylmethane
niguldipine[no description available]low00diarylmethane
mandrax[no description available]low00diarylmethane
droprenylamine[no description available]low00diarylmethane
quifenadine[no description available]low00diarylmethane
carebastine[no description available]low00diarylmethane
lercanidipine[no description available]low00diarylmethane
diphenidol hydrochloride[no description available]low00diarylmethane
dioxadrol[no description available]low00diarylmethane
budipine[no description available]low00diarylmethane
epicainide[no description available]low00diarylmethane
denaverine[no description available]low00diarylmethane
lifarizine[no description available]low00diarylmethane
fenpiverinium[no description available]low00diarylmethane
2,2-methylenebis(4-chloro-3-methyl-isopropylphenol)[no description available]low00diarylmethane
amperozide[no description available]low00diarylmethane;
monofluorobenzenes;
N-alkylpiperazine;
secondary carboxamide;
ureas		anxiolytic drug;
dopamine uptake inhibitor;
geroprotector;
second generation antipsychotic;
serotonergic antagonist
2,2'-bisphenol f[no description available]low00diarylmethane
3-hydroxy-2,2-diphenylpropanoic acid[no description available]low00diarylmethane
1,1-Dichloro-2,2-bis(4-hydroxyphenyl)ethylene[no description available]low00diarylmethane
bisphenol f diglycidyl ether[no description available]low00aromatic ether;
diarylmethane;
epoxide
n-(4,4-diphenyl-3-butenyl)nipecotic acid[no description available]low00diarylmethane
methylene bis(methylanthranilate)[no description available]low00diarylmethane
tesmilifene[no description available]low00diarylmethane
pd 123177[no description available]low00diarylmethane
bw 373u86[no description available]low00diarylmethane
gilutensin hydrochloride[no description available]low00diarylmethane
4-(alpha-(4-allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl)-n,n-diethylbenzamide[no description available]low00diarylmethane
ae0047[no description available]low00diarylmethane
lercanidipine hydrochloride[no description available]low00diarylmethane
cloperastine hydrochloride[no description available]low00diarylmethane
1,1,1-trichloro-2-(4-hydroxyphenyl)-2-(4-methoxyphenyl)ethane[no description available]low00diarylmethane
2-[(4,6-dimethyl-2-pyrimidinyl)oxy]-3-methoxy-3,3-diphenylpropanoic acid[no description available]low00diarylmethane
ci 966[no description available]low00diarylmethane
Difeterol[no description available]low00diarylmethane
1,1-bis(4-hydroxyphenyl)cyclohexane[no description available]low00diarylmethane
2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene[no description available]low00diarylmethane
propiverine hydrochloride[no description available]low00diarylmethane
gw 3965[no description available]low00diarylmethane
1,1-Bis(4-hydroxyphenyl)ethane[no description available]low00diarylmethane
uk 78282[no description available]low00diarylmethane
r 59949[no description available]low00diarylmethane
4-[1-(4-hydroxyphenyl)ethenyl]phenol[no description available]low00diarylmethane
5-[4-(diphenylmethyl)-1-piperazinyl]-2-(2-methoxyphenyl)-4-oxazolecarbonitrile[no description available]low00diarylmethane
flunarizine[no description available]low00diarylmethane
N-[4-[oxo-[(1-oxo-2,2-diphenylethyl)hydrazo]methyl]phenyl]propanamide[no description available]low00diarylmethane
[4-(diphenylmethyl)-1-piperazinyl]-[5-thiophen-2-yl-7-(trifluoromethyl)-3-pyrazolo[1,5-a]pyrimidinyl]methanone[no description available]low00diarylmethane
benztropine[no description available]low00diarylmethane
3-[[[(1-oxo-2,2-diphenylethyl)amino]-sulfanylidenemethyl]amino]benzoic acid[no description available]low00diarylmethane
3-bromo-5-[[4-[hydroxy(diphenyl)methyl]-1-piperidinyl]-oxomethyl]-2-pyranone[no description available]low00diarylmethane
2-(5-bromo-3-nitro-1,2,4-triazol-1-yl)-N-(diphenylmethyl)acetamide[no description available]low00diarylmethane
1,1-bis(4-chlorophenyl)-2-[(3-methoxyphenyl)methylamino]ethanol[no description available]low00diarylmethane
cinnarizine[no description available]low00diarylmethane;
N-alkylpiperazine;
olefinic compound		anti-allergic agent;
antiemetic;
calcium channel blocker;
geroprotector;
H1-receptor antagonist;
histamine antagonist;
muscarinic antagonist
levocetirizine[no description available]low00diarylmethane
amn082[no description available]low00benzenes;
diamine;
diarylmethane;
secondary amino compound		metabotropic glutamate receptor agonist;
neuroprotective agent
N-[2-[tert-butyl(methyl)amino]ethyl]-N-methyl-2,2-diphenylacetamide[no description available]low00diarylmethane
N-(4-fluorophenyl)-4-[hydroxy(diphenyl)methyl]-1-piperidinecarbothioamide[no description available]low00diarylmethane
4-oxo-3-[(1-oxo-2,2-diphenylethyl)amino]-2-sulfanylidene-1H-quinazoline-7-carboxylic acid methyl ester[no description available]low00diarylmethane
2,2-diphenylacetic acid (2,6-dimethylphenyl) ester[no description available]low00diarylmethane
1-ethyl-3-[(1-oxo-2,2-diphenylethyl)amino]thiourea[no description available]low00diarylmethane
2-(phenylmethyl)benzoic acid [2-[4-(difluoromethylthio)anilino]-2-oxoethyl] ester[no description available]low00diarylmethane
2-[2-[bis(4-methoxyphenyl)methylidene]hydrazinyl]benzoic acid[no description available]low00diarylmethane
N-[4-bromo-2-[[(2-hydrazinyl-2-oxoethyl)amino]-phenylmethyl]phenyl]-3-(4-morpholinyl)propanamide[no description available]low00diarylmethane
N-(4-ethoxyphenyl)-4-[hydroxy(diphenyl)methyl]-1-piperidinecarbothioamide[no description available]low00diarylmethane
4-[hydroxy(diphenyl)methyl]-N-(2-phenylethyl)-1-piperidinecarbothioamide[no description available]low00diarylmethane
3-(5-chloro-2-hydroxyphenyl)-3-phenyl-N-[(4-propan-2-yloxyphenyl)methyl]propanamide[no description available]low00diarylmethane
adrafinil[no description available]low00diarylmethane
zamifenacin[no description available]low00diarylmethane
2-(cyclohexylamino)-N-[(diphenylmethylene)amino]propanamide[no description available]low00diarylmethane
3-[[4-(diphenylmethyl)-1-piperazinyl]-oxomethyl]-7,8,9,10-tetrahydro-6H-azepino[2,1-b]quinazolin-12-one[no description available]low00diarylmethane
3-[bis(4-fluorophenyl)methoxy]-8-methyl-8-azabicyclo[3.2.1]octane[no description available]low00diarylmethane
flunarizine hydrochloride[no description available]low00diarylmethane
(2-amino-5-chlorophenyl)(phenyl)methanone oxime[no description available]low00diarylmethane
imidafenacin[no description available]low00diarylmethane
2-(3,3-diphenylpropylamino)acetamide[no description available]low00diarylmethane
cgk 733[no description available]low00diarylmethane
dexniguldipine[no description available]low00diarylmethane
lu 208075[no description available]low00diarylmethane
fesoterodine[no description available]low00diarylmethane
3-(diphenylmethylene)-1-[4-(4-phenyl-1-piperazinyl)butyl]pyrrolidine-2,5-dione[no description available]low00diarylmethane
pnu 200577[no description available]low00diarylmethane
gc 1 compound[no description available]low00diarylmethane
tas 301[no description available]low00diarylmethane
1,5-anhydro-1-(5-(4-ethoxybenzyl)-2-methoxy-4-methylphenyl)-1-thioglucitol[no description available]low00diarylmethane
[4-(diphenylmethyl)-1-piperazinyl]-(5-methyl-4-nitro-3-isoxazolyl)methanone[no description available]low00diarylmethane
1-(1,4-dioxan-2-yl)-N-[[3-(diphenylmethyl)-1,2,4-oxadiazol-5-yl]methyl]-N-methylmethanamine[no description available]low00diarylmethane
1-[4-(3-chlorophenyl)-1-piperazinyl]-3-(diphenylmethyl)oxy-2-propanol[no description available]low00diarylmethane
(8R)-3-[3-[[2-(4-chlorophenoxy)-1-oxoethyl]amino]phenyl]-7-(1-oxo-3,3-diphenylpropyl)-1-oxa-2,7-diazaspiro[4.4]non-2-ene-8-carboxamide[no description available]low00diarylmethane
3-(2-hydroxy-4,6-dimethoxyphenyl)-3-(4-methoxyphenyl)-1-(3-methyl-1-piperidinyl)-1-propanone[no description available]low00diarylmethane
2-[[[4-[[(diphenylmethyl)amino]-oxomethyl]-1H-imidazol-5-yl]-oxomethyl]amino]acetic acid tert-butyl ester[no description available]low00diarylmethane;
tert-butyl ester
pf 04971729[no description available]low00diarylmethane
ML-210[no description available]low00C-nitro compound;
diarylmethane;
isoxazoles;
monochlorobenzenes;
N-acylpiperazine;
N-alkylpiperazine;
tertiary carboxamide		antineoplastic agent;
EC 1.11.1.9 (glutathione peroxidase) inhibitor;
ferroptosis inducer;
prodrug
ConditionIndicatedRelationship StrengthStudiesTrials
Congenital Zika Syndrome0low10
Congenital Zika Virus Infection0low10
Disease Models, Animal0low10
Fever, Zika0low10
Inflammation0low10
Innate Inflammatory Response0low10
Malaria, Falciparum0low10
Plasmodium falciparum Malaria0low10
Zika Fever0low10
Zika Virus Disease0low10
Zika Virus Infection0low10
ZikV Infection0low10

Research Highlights

Bioavailability (2)

ArticleYear
A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
Molecular pharmacology, Volume: 96, Issue: 5		2019
Physiologically relevant orthogonal assays for the discovery of small-molecule modulators of WIP1 phosphatase in high-throughput screens.
The Journal of biological chemistry, 11-15, Volume: 294, Issue: 46		2019
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]