| Assay ID | Title | Year | Journal | Article |
|---|
| AID362637 | Inhibition of bovine alpha chymotrypsin | 2008 | Journal of natural products, Sep, Volume: 71, Issue:9
| Kempopeptins A and B, serine protease inhibitors with different selectivity profiles from a marine cyanobacterium, Lyngbya sp. |
| AID1548345 | Inhibition of human neutrophil elastase using N-(OMe-succinyl)-Ala-Ala-Pro-Val-p-nitroanilide as substrate incubated for 15 mins followed by substrate addition and measured for every 30 sec for 30 mins by spectrophotometry | 2020 | ACS medicinal chemistry letters, Apr-09, Volume: 11, Issue:4
| Ahp-Cyclodepsipeptide Inhibitors of Elastase: Lyngbyastatin 7 Stability, Scalable Synthesis, and Focused Library Analysis. |
| AID1548342 | Stability in human serum at 200 uM incubated for 24 hrs by HPLC-MS analysis | 2020 | ACS medicinal chemistry letters, Apr-09, Volume: 11, Issue:4
| Ahp-Cyclodepsipeptide Inhibitors of Elastase: Lyngbyastatin 7 Stability, Scalable Synthesis, and Focused Library Analysis. |
| AID1548347 | Upregulation of IL-1beta in human BEAS2B cells incubated for 24 hrs by RT-qPCR analysis | 2020 | ACS medicinal chemistry letters, Apr-09, Volume: 11, Issue:4
| Ahp-Cyclodepsipeptide Inhibitors of Elastase: Lyngbyastatin 7 Stability, Scalable Synthesis, and Focused Library Analysis. |
| AID732628 | Inhibition of human neutrophil elastase assessed as proteolysis using N-(methoxysuccinyl)-Ala-Ala-Pro-Val-p-nitroanilide substrate incubated for 15 mins prior to substrate addition measured every 30 seconds | 2013 | Journal of medicinal chemistry, Feb-14, Volume: 56, Issue:3
| Potent elastase inhibitors from cyanobacteria: structural basis and mechanisms mediating cytoprotective and anti-inflammatory effects in bronchial epithelial cells. |
| AID1548343 | Metabolic stability in human liver microsomes at 200 uM incubated for 24 hrs by HPLC-MS analysis | 2020 | ACS medicinal chemistry letters, Apr-09, Volume: 11, Issue:4
| Ahp-Cyclodepsipeptide Inhibitors of Elastase: Lyngbyastatin 7 Stability, Scalable Synthesis, and Focused Library Analysis. |
| AID362638 | Inhibition of pig pancreatic elastase | 2008 | Journal of natural products, Sep, Volume: 71, Issue:9
| Kempopeptins A and B, serine protease inhibitors with different selectivity profiles from a marine cyanobacterium, Lyngbya sp. |
| AID1548346 | Cytoprotective activity in human BEAS2B cells assessed as reduction in HNE-induced cell death incubated for 24 hrs by MTT assay | 2020 | ACS medicinal chemistry letters, Apr-09, Volume: 11, Issue:4
| Ahp-Cyclodepsipeptide Inhibitors of Elastase: Lyngbyastatin 7 Stability, Scalable Synthesis, and Focused Library Analysis. |
| AID732626 | Inhibition of human pancreatic chymotrypsin assessed as proteolysis using N-succinyl-Ala-Ala-Pro-Phe-p-nitroanilide substrate incubated for 30 mins prior to substrate addition | 2013 | Journal of medicinal chemistry, Feb-14, Volume: 56, Issue:3
| Potent elastase inhibitors from cyanobacteria: structural basis and mechanisms mediating cytoprotective and anti-inflammatory effects in bronchial epithelial cells. |
| AID311583 | Inhibition of bovine alpha chymotrypsin | 2007 | Journal of natural products, Oct, Volume: 70, Issue:10
| Lyngbyastatins 5-7, potent elastase inhibitors from Floridian marine cyanobacteria, Lyngbya spp. |
| AID732629 | Inhibition of porcine pancreatic elastase assessed as proteolysis using N-succinyl-Ala-Ala-Ala-p-nitroanilide substrate incubated for 15 mins prior to substrate addition measured every 30 seconds | 2013 | Journal of medicinal chemistry, Feb-14, Volume: 56, Issue:3
| Potent elastase inhibitors from cyanobacteria: structural basis and mechanisms mediating cytoprotective and anti-inflammatory effects in bronchial epithelial cells. |
| AID732627 | Inhibition of bovine pancreatic chymotrypsin assessed as proteolysis using N-succinyl-Gly-Gly-Phe-p-nitroanilide substrate incubated for 30 mins prior to substrate addition | 2013 | Journal of medicinal chemistry, Feb-14, Volume: 56, Issue:3
| Potent elastase inhibitors from cyanobacteria: structural basis and mechanisms mediating cytoprotective and anti-inflammatory effects in bronchial epithelial cells. |
| AID311584 | Inhibition of pig trypsin up to 30 uM | 2007 | Journal of natural products, Oct, Volume: 70, Issue:10
| Lyngbyastatins 5-7, potent elastase inhibitors from Floridian marine cyanobacteria, Lyngbya spp. |
| AID1548344 | Metabolic stability in human liver microsome assessed as half life at 200 uM in presence of NADPH incubated for 24 hrs by HPLC-MS analysis | 2020 | ACS medicinal chemistry letters, Apr-09, Volume: 11, Issue:4
| Ahp-Cyclodepsipeptide Inhibitors of Elastase: Lyngbyastatin 7 Stability, Scalable Synthesis, and Focused Library Analysis. |
| AID362639 | Inhibition of pig pancreatic trypsin | 2008 | Journal of natural products, Sep, Volume: 71, Issue:9
| Kempopeptins A and B, serine protease inhibitors with different selectivity profiles from a marine cyanobacterium, Lyngbya sp. |
| AID311582 | Inhibition of pig elastase | 2007 | Journal of natural products, Oct, Volume: 70, Issue:10
| Lyngbyastatins 5-7, potent elastase inhibitors from Floridian marine cyanobacteria, Lyngbya spp. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |