Compounds > sulfoquinovosyl dipalmitoyl glyceride
Page last updated: 2024-12-08
sulfoquinovosyl dipalmitoyl glyceride
Description
sulfoquinovosyl dipalmitoyl glyceride: P-selectin receptor inhibitor; isolated from the alga Dictyochloris fragrans; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
| ID Source | ID |
|---|
| PubMed CID | 159321 |
| CHEMBL ID | 504516 |
| SCHEMBL ID | 6925719 |
| MeSH ID | M0276384 |
Synonyms (13)
| Synonym |
|---|
| sulfonoglycolipid |
| brn 1279617 |
| 2,3-bis((1-oxohexadecyl)oxy)propyl 6-deoxy-6-sulfo-alpha-d-glucopyranoside |
| sulfoquinovosyl dipalmitoyl glyceride |
| alpha-d-glucopyranoside, 2,3-bis((1-oxohexadecyl)oxy)propyl 6-deoxy-6-sulfo- |
| 109430-50-4 |
| sulfonoquinovosyl dipalmitoyl glyceride |
| CHEMBL504516 , |
| [(2s,3s,4s,5r,6s)-6-[2,3-di(hexadecanoyloxy)propoxy]-3,4,5-trihydroxyoxan-2-yl]methanesulfonic acid |
| bdbm50292392 |
| SCHEMBL6925719 |
| DTXSID40911161 |
| 1,2-dipalmitoyl-3-o-alpha-6'''-sulfoquinovosylglycerol |
Protein Targets (1)
Inhibition Measurements
| Protein | Taxonomy | Measurement | Average | Min (ref.) | Avg (ref.) | Max (ref.) | Bioassay(s) |
|---|
| P-selectin | Homo sapiens (human) | IC50 (µMol) | 5.0000 | 5.0000 | 5.0000 | 5.0000 | AID403206 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] |
Biological Processes (15)
Molecular Functions (10)
Ceullar Components (5)
Bioassays (3)
| Assay ID | Title | Year | Journal | Article |
|---|
| AID403206 | Displacement of immobilized sulfatide from P-selectin transfected in african green monkey COS cells by IgG-based competitive ELISA | 1997 | Journal of natural products, Apr, Volume: 60, Issue:4
| Isolation and structure determination of sulfonoquinovosyl dipalmitoyl glyceride, a P-selectin receptor inhibitor from the alga Dictyochloris fragrans. |
| AID403208 | Inhibition of human P-selectin-dependent adhesion of activated platelets to HL60 cells after 30 mins by flow cytometry | 1997 | Journal of natural products, Apr, Volume: 60, Issue:4
| Isolation and structure determination of sulfonoquinovosyl dipalmitoyl glyceride, a P-selectin receptor inhibitor from the alga Dictyochloris fragrans. |
| AID403207 | Inhibition of human P-selectin receptor globulin adhesion to HL60 cells | 1997 | Journal of natural products, Apr, Volume: 60, Issue:4
| Isolation and structure determination of sulfonoquinovosyl dipalmitoyl glyceride, a P-selectin receptor inhibitor from the alga Dictyochloris fragrans. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Research
Studies (5)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Market Indicators
Research Demand Index: 12.76
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| Metric | This Compound (vs All) |
|---|
| Research Demand Index | 12.76 (24.57) | | Research Supply Index | 1.79 (2.92) | | Research Growth Index | 4.55 (4.65) | | Search Engine Demand Index | 0.00 (26.88) | | Search Engine Supply Index | 0.00 (0.95) |
| |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 5 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |