| Assay ID | Title | Year | Journal | Article |
|---|
| AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1
| High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID651635 | Viability Counterscreen for Primary qHTS for Inhibitors of ATXN expression | | | |
| AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1
| High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1
| High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID1745845 | Primary qHTS for Inhibitors of ATXN expression | | | |
| AID317243 | Inhibition of CK2 in rat liver | 2008 | Journal of medicinal chemistry, Feb-28, Volume: 51, Issue:4
| Coumarin as attractive casein kinase 2 (CK2) inhibitor scaffold: an integrate approach to elucidate the putative binding motif and explain structure-activity relationships. |
| AID715783 | Induction of cell differentiation in human U937 cells assessed as increase of CD11b and CD14 expression at 500 uM after 72 hrs by FACS flow cytometer analysis | 2012 | Bioorganic & medicinal chemistry, Sep-15, Volume: 20, Issue:18
| Structure-anti-leukemic activity relationship study of ortho-dihydroxycoumarins in U-937 cells: key role of the δ-lactone ring in determining differentiation-inducing potency and selective pro-apoptotic action. |
| AID541338 | Inhibition of alpha-glucosidase using para-nitrophenyl substrate | 2010 | Journal of medicinal chemistry, Dec-09, Volume: 53, Issue:23
| Hydroxycoumarin derivatives: novel and potent α-glucosidase inhibitors. |
| AID541341 | Inhibition of Aspergillus oryzae Beta-galactosidase | 2010 | Journal of medicinal chemistry, Dec-09, Volume: 53, Issue:23
| Hydroxycoumarin derivatives: novel and potent α-glucosidase inhibitors. |
| AID715803 | Antiproliferative activity against human U937 cells assessed as incorporation of [3H]-methyl-thymidine after 12 hrs by scintillation counting | 2012 | Bioorganic & medicinal chemistry, Sep-15, Volume: 20, Issue:18
| Structure-anti-leukemic activity relationship study of ortho-dihydroxycoumarins in U-937 cells: key role of the δ-lactone ring in determining differentiation-inducing potency and selective pro-apoptotic action. |
| AID568484 | Antimicrobial activity against Bacillus subtilis ATCC 6633 by twofold broth dilution method | 2011 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3
| Synthesis and evaluation of a class of new coumarin triazole derivatives as potential antimicrobial agents. |
| AID34797 | Compound was tested for inhibitory concentration against rat lens aldose reductase (noncompetitive inhibition type) | 1986 | Journal of medicinal chemistry, Jun, Volume: 29, Issue:6
| Synthesis and rat lens aldose reductase inhibitory activity of some benzopyran-2-ones. |
| AID977602 | Inhibition of sodium fluorescein uptake in OATP1B3-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM | 2013 | Molecular pharmacology, Jun, Volume: 83, Issue:6
| Structure-based identification of OATP1B1/3 inhibitors. |
| AID715793 | Induction of apoptosis in human U937 cells assessed as activation of caspase-3 at 500 uM after 24 hrs by colorimetric assay | 2012 | Bioorganic & medicinal chemistry, Sep-15, Volume: 20, Issue:18
| Structure-anti-leukemic activity relationship study of ortho-dihydroxycoumarins in U-937 cells: key role of the δ-lactone ring in determining differentiation-inducing potency and selective pro-apoptotic action. |
| AID1328524 | Gastroprotective activity in Swiss albino mouse assessed as reduction in HCl/EtOH-induced gastric lesions at 20 mg/kg, po pretreated for 50 mins followed by HCl/EtOH challenge measured after 1 hr | 2016 | Bioorganic & medicinal chemistry letters, 12-01, Volume: 26, Issue:23
| Gastroprotective activity of synthetic coumarins: Role of endogenous prostaglandins, nitric oxide, non-protein sulfhydryls and vanilloid receptors. |
| AID541494 | Inhibition of beta-glucosidase using salicin substrate | 2010 | Journal of medicinal chemistry, Dec-09, Volume: 53, Issue:23
| Hydroxycoumarin derivatives: novel and potent α-glucosidase inhibitors. |
| AID568489 | Antimicrobial activity against Shigella dysenteriae ATCC 49550 by twofold broth dilution method | 2011 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3
| Synthesis and evaluation of a class of new coumarin triazole derivatives as potential antimicrobial agents. |
| AID568485 | Antimicrobial activity against Micrococcus luteus ATCC 4698 by twofold broth dilution method | 2011 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3
| Synthesis and evaluation of a class of new coumarin triazole derivatives as potential antimicrobial agents. |
| AID715795 | Induction of apoptosis in human U937 cells assessed as reduction of normal cells at 500 uM after 24 hrs by Annexin V-FITC double staining | 2012 | Bioorganic & medicinal chemistry, Sep-15, Volume: 20, Issue:18
| Structure-anti-leukemic activity relationship study of ortho-dihydroxycoumarins in U-937 cells: key role of the δ-lactone ring in determining differentiation-inducing potency and selective pro-apoptotic action. |
| AID458279 | Displacement of FITC-CKLF1-C27 from human CCR4 receptor expressed in human HEK293 cells at 10 uM | 2010 | Journal of medicinal chemistry, Feb-25, Volume: 53, Issue:4
| Discovery and optimization of novel 3-piperazinylcoumarin antagonist of chemokine-like factor 1 with oral antiasthma activity in mice. |
| AID568492 | Antifungal activity against Aspergillus fumigatus ATCC 96918 by twofold broth dilution method | 2011 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3
| Synthesis and evaluation of a class of new coumarin triazole derivatives as potential antimicrobial agents. |
| AID568482 | Antimicrobial activity against Staphylococcus aureus ATCC 25923 by twofold broth dilution method | 2011 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3
| Synthesis and evaluation of a class of new coumarin triazole derivatives as potential antimicrobial agents. |
| AID568488 | Antimicrobial activity against Salmonella typhi ATCC 9484 by twofold broth dilution method | 2011 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3
| Synthesis and evaluation of a class of new coumarin triazole derivatives as potential antimicrobial agents. |
| AID541342 | Inhibition of Aspergillus oryzae Beta-galactosidase at 400 uM | 2010 | Journal of medicinal chemistry, Dec-09, Volume: 53, Issue:23
| Hydroxycoumarin derivatives: novel and potent α-glucosidase inhibitors. |
| AID568483 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus N 315 by twofold broth dilution method | 2011 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3
| Synthesis and evaluation of a class of new coumarin triazole derivatives as potential antimicrobial agents. |
| AID715802 | Cytotoxicity against human U937 cells after 48 hrs by trypan blue assay | 2012 | Bioorganic & medicinal chemistry, Sep-15, Volume: 20, Issue:18
| Structure-anti-leukemic activity relationship study of ortho-dihydroxycoumarins in U-937 cells: key role of the δ-lactone ring in determining differentiation-inducing potency and selective pro-apoptotic action. |
| AID977599 | Inhibition of sodium fluorescein uptake in OATP1B1-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM | 2013 | Molecular pharmacology, Jun, Volume: 83, Issue:6
| Structure-based identification of OATP1B1/3 inhibitors. |
| AID568487 | Antimicrobial activity against Proteus vulgaris ATCC 6896 by twofold broth dilution method | 2011 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3
| Synthesis and evaluation of a class of new coumarin triazole derivatives as potential antimicrobial agents. |
| AID568486 | Antimicrobial activity against Escherichia coli ATCC 25922 by twofold broth dilution method | 2011 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3
| Synthesis and evaluation of a class of new coumarin triazole derivatives as potential antimicrobial agents. |
| AID568491 | Antifungal activity against Saccharomyces cerevisiae ATCC 9763 by twofold broth dilution method | 2011 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3
| Synthesis and evaluation of a class of new coumarin triazole derivatives as potential antimicrobial agents. |
| AID568490 | Antifungal activity against Candida albicans ATCC 76615 by twofold broth dilution method | 2011 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3
| Synthesis and evaluation of a class of new coumarin triazole derivatives as potential antimicrobial agents. |
| AID1159550 | Human Phosphogluconate dehydrogenase (6PGD) Inhibitor Screening | 2015 | Nature cell biology, Nov, Volume: 17, Issue:11
| 6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling. |
| AID1803437 | CA Inhibition Assay from Article 10.3109/14756366.2013.777334: \\Novel coumarins and benzocoumarins acting as isoform-selective inhibitors against the tumor-associated carbonic anhydrase IX.\\ | 2014 | Journal of enzyme inhibition and medicinal chemistry, Apr, Volume: 29, Issue:2
| Novel coumarins and benzocoumarins acting as isoform-selective inhibitors against the tumor-associated carbonic anhydrase IX. |
| AID1799899 | NS5B Inhibition Assay from Article 10.1111/cbdd.12105: \\Evaluation of Coumarin and Neoflavone Derivatives as HCV NS5B Polymerase Inhibitors.\\ | 2013 | Chemical biology & drug design, May, Volume: 81, Issue:5
| Evaluation of coumarin and neoflavone derivatives as HCV NS5B polymerase inhibitors. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |