| Assay ID | Title | Year | Journal | Article |
|---|
| AID1346986 | P-glycoprotein substrates identified in KB-3-1 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5
| A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
| AID1347160 | Primary screen NINDS Rhodamine qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1347159 | Primary screen GU Rhodamine qHTS for Zika virus inhibitors: Unlinked NS2B-NS3 protease assay | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1296008 | Cytotoxic Profiling of Annotated Libraries Using Quantitative High-Throughput Screening | 2020 | SLAS discovery : advancing life sciences R & D, 01, Volume: 25, Issue:1
| Cytotoxic Profiling of Annotated and Diverse Chemical Libraries Using Quantitative High-Throughput Screening. |
| AID1346987 | P-glycoprotein substrates identified in KB-8-5-11 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5
| A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
| AID620887 | Inhibition of food intake in rat after 24 hrs starvation | 2011 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 21, Issue:18
| Discovery of Lu AA33810: a highly selective and potent NPY5 antagonist with in vivo efficacy in a model of mood disorder. |
| AID620866 | Intrinsic clearance in rat liver microsome | 2011 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 21, Issue:18
| Discovery of Lu AA33810: a highly selective and potent NPY5 antagonist with in vivo efficacy in a model of mood disorder. |
| AID620885 | Volume of distribution at steady state in Sprague-Dawley rat at 1 mg/kg, iv and 2 mg/kg, po by HPLC analysis | 2011 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 21, Issue:18
| Discovery of Lu AA33810: a highly selective and potent NPY5 antagonist with in vivo efficacy in a model of mood disorder. |
| AID620863 | Antagonist activity at human NPY2 receptor assessed as calcium mobilization by FLIPR assay | 2011 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 21, Issue:18
| Discovery of Lu AA33810: a highly selective and potent NPY5 antagonist with in vivo efficacy in a model of mood disorder. |
| AID620913 | Plasma concentration in cPP-induced feeding rat model at 30 mg/kg, po after 6 hrs | 2011 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 21, Issue:18
| Discovery of Lu AA33810: a highly selective and potent NPY5 antagonist with in vivo efficacy in a model of mood disorder. |
| AID620912 | Plasma concentration in cPP-induced feeding rat model at 30 mg/kg, po after 4 hrs | 2011 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 21, Issue:18
| Discovery of Lu AA33810: a highly selective and potent NPY5 antagonist with in vivo efficacy in a model of mood disorder. |
| AID620880 | Apparent permeability from basolateral to apical side of the human Caco2 cells | 2011 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 21, Issue:18
| Discovery of Lu AA33810: a highly selective and potent NPY5 antagonist with in vivo efficacy in a model of mood disorder. |
| AID620916 | Drug uptake in brain of cPP-induced feeding rat model at 30 mg/kg, po after 2 hrs | 2011 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 21, Issue:18
| Discovery of Lu AA33810: a highly selective and potent NPY5 antagonist with in vivo efficacy in a model of mood disorder. |
| AID620864 | Antagonist activity at human NPY4 receptor assessed as calcium mobilization by FLIPR assay | 2011 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 21, Issue:18
| Discovery of Lu AA33810: a highly selective and potent NPY5 antagonist with in vivo efficacy in a model of mood disorder. |
| AID620907 | Drug uptake in brain of cPP-induced feeding rat model at 10 mg/kg, po after 4 hrs | 2011 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 21, Issue:18
| Discovery of Lu AA33810: a highly selective and potent NPY5 antagonist with in vivo efficacy in a model of mood disorder. |
| AID620928 | Half life in mouse at 1 mg/kg, iv and 2 mg/kg, po by HPLC analysis | 2011 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 21, Issue:18
| Discovery of Lu AA33810: a highly selective and potent NPY5 antagonist with in vivo efficacy in a model of mood disorder. |
| AID620873 | Plasma protein binding in human | 2011 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 21, Issue:18
| Discovery of Lu AA33810: a highly selective and potent NPY5 antagonist with in vivo efficacy in a model of mood disorder. |
| AID620914 | Plasma concentration in cPP-induced feeding rat model at 30 mg/kg, po after 24 hrs | 2011 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 21, Issue:18
| Discovery of Lu AA33810: a highly selective and potent NPY5 antagonist with in vivo efficacy in a model of mood disorder. |
| AID620893 | Plasma concentration in cPP-induced feeding rat model at 3 mg/kg, po after 6 hrs | 2011 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 21, Issue:18
| Discovery of Lu AA33810: a highly selective and potent NPY5 antagonist with in vivo efficacy in a model of mood disorder. |
| AID620865 | Intrinsic clearance in human liver microsome | 2011 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 21, Issue:18
| Discovery of Lu AA33810: a highly selective and potent NPY5 antagonist with in vivo efficacy in a model of mood disorder. |
| AID620869 | Binding affinity to human 5HT2B receptor | 2011 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 21, Issue:18
| Discovery of Lu AA33810: a highly selective and potent NPY5 antagonist with in vivo efficacy in a model of mood disorder. |
| AID620877 | Inhibition of CYP2C19 | 2011 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 21, Issue:18
| Discovery of Lu AA33810: a highly selective and potent NPY5 antagonist with in vivo efficacy in a model of mood disorder. |
| AID620862 | Antagonist activity at human NPY1 receptor assessed as calcium mobilization by FLIPR assay | 2011 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 21, Issue:18
| Discovery of Lu AA33810: a highly selective and potent NPY5 antagonist with in vivo efficacy in a model of mood disorder. |
| AID620874 | Inhibition of CYP3A4 | 2011 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 21, Issue:18
| Discovery of Lu AA33810: a highly selective and potent NPY5 antagonist with in vivo efficacy in a model of mood disorder. |
| AID620917 | Drug uptake in brain of cPP-induced feeding rat model at 30 mg/kg, po after 4 hrs | 2011 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 21, Issue:18
| Discovery of Lu AA33810: a highly selective and potent NPY5 antagonist with in vivo efficacy in a model of mood disorder. |
| AID620878 | Inhibition of CYP2D6 | 2011 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 21, Issue:18
| Discovery of Lu AA33810: a highly selective and potent NPY5 antagonist with in vivo efficacy in a model of mood disorder. |
| AID620901 | Plasma concentration in cPP-induced feeding rat model at 10 mg/kg, po after 2 hrs | 2011 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 21, Issue:18
| Discovery of Lu AA33810: a highly selective and potent NPY5 antagonist with in vivo efficacy in a model of mood disorder. |
| AID620926 | Tmax in mouse at 1 mg/kg, iv and 2 mg/kg, po by HPLC analysis | 2011 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 21, Issue:18
| Discovery of Lu AA33810: a highly selective and potent NPY5 antagonist with in vivo efficacy in a model of mood disorder. |
| AID620919 | Drug uptake in brain of cPP-induced feeding rat model at 30 mg/kg, po after 24 hrs | 2011 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 21, Issue:18
| Discovery of Lu AA33810: a highly selective and potent NPY5 antagonist with in vivo efficacy in a model of mood disorder. |
| AID625640 | Intrinsic clearance in human liver microsomes | 2011 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 21, Issue:21
| 5-(2'-Pyridyl)-2-aminothiazoles: alkyl amino sulfonamides and sulfamides as potent NPY(5) antagonists. |
| AID620921 | Antagonist activity at rat NPY5 receptor | 2011 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 21, Issue:18
| Discovery of Lu AA33810: a highly selective and potent NPY5 antagonist with in vivo efficacy in a model of mood disorder. |
| AID625646 | Absolute oral bioavailability in Sprague-Dawley rat at 2 mg/kg by HPLC method | 2011 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 21, Issue:21
| 5-(2'-Pyridyl)-2-aminothiazoles: alkyl amino sulfonamides and sulfamides as potent NPY(5) antagonists. |
| AID620898 | Drug uptake in brain of cPP-induced feeding rat model at 3 mg/kg, po after 6 hrs | 2011 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 21, Issue:18
| Discovery of Lu AA33810: a highly selective and potent NPY5 antagonist with in vivo efficacy in a model of mood disorder. |
| AID620871 | Inhibition of human ERG by patch-clamp assay | 2011 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 21, Issue:18
| Discovery of Lu AA33810: a highly selective and potent NPY5 antagonist with in vivo efficacy in a model of mood disorder. |
| AID620911 | Plasma concentration in cPP-induced feeding rat model at 30 mg/kg, po after 2 hrs | 2011 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 21, Issue:18
| Discovery of Lu AA33810: a highly selective and potent NPY5 antagonist with in vivo efficacy in a model of mood disorder. |
| AID620920 | Free drug level in brain of cPP-induced feeding rat model | 2011 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 21, Issue:18
| Discovery of Lu AA33810: a highly selective and potent NPY5 antagonist with in vivo efficacy in a model of mood disorder. |
| AID620884 | Tmax in Sprague-Dawley rat at 1 mg/kg, iv and 2 mg/kg, po by HPLC analysis | 2011 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 21, Issue:18
| Discovery of Lu AA33810: a highly selective and potent NPY5 antagonist with in vivo efficacy in a model of mood disorder. |
| AID620908 | Drug uptake in brain of cPP-induced feeding rat model at 10 mg/kg, po after 6 hrs | 2011 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 21, Issue:18
| Discovery of Lu AA33810: a highly selective and potent NPY5 antagonist with in vivo efficacy in a model of mood disorder. |
| AID620891 | Plasma concentration in cPP-induced feeding rat model at 3 mg/kg, po after 2 hrs | 2011 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 21, Issue:18
| Discovery of Lu AA33810: a highly selective and potent NPY5 antagonist with in vivo efficacy in a model of mood disorder. |
| AID620889 | Inhibition of cPP-induced food intake in rat at 3 mg/kg, po administered 1 to 24 hrs before cPP challenge measured for 1 hr | 2011 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 21, Issue:18
| Discovery of Lu AA33810: a highly selective and potent NPY5 antagonist with in vivo efficacy in a model of mood disorder. |
| AID620924 | Oral bioavailability in mouse at 2 mg/kg by HPLC analysis | 2011 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 21, Issue:18
| Discovery of Lu AA33810: a highly selective and potent NPY5 antagonist with in vivo efficacy in a model of mood disorder. |
| AID625645 | Volume of distribution at steady state in Sprague-Dawley rat at 2 mg/kg, po and 1 mg/kg, iv by HPLC method | 2011 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 21, Issue:21
| 5-(2'-Pyridyl)-2-aminothiazoles: alkyl amino sulfonamides and sulfamides as potent NPY(5) antagonists. |
| AID620890 | Plasma concentration in cPP-induced feeding rat model at 3 mg/kg, po after 1 hr | 2011 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 21, Issue:18
| Discovery of Lu AA33810: a highly selective and potent NPY5 antagonist with in vivo efficacy in a model of mood disorder. |
| AID620903 | Plasma concentration in cPP-induced feeding rat model at 10 mg/kg, po after 6 hrs | 2011 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 21, Issue:18
| Discovery of Lu AA33810: a highly selective and potent NPY5 antagonist with in vivo efficacy in a model of mood disorder. |
| AID620867 | Plasma concentration in rat at 10 mg/kg, po after 4 hrs | 2011 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 21, Issue:18
| Discovery of Lu AA33810: a highly selective and potent NPY5 antagonist with in vivo efficacy in a model of mood disorder. |
| AID625641 | Intrinsic clearance in rat liver microsomes | 2011 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 21, Issue:21
| 5-(2'-Pyridyl)-2-aminothiazoles: alkyl amino sulfonamides and sulfamides as potent NPY(5) antagonists. |
| AID620927 | Volume of distribution at steady state in mouse at 1 mg/kg, iv and 2 mg/kg, po by HPLC analysis | 2011 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 21, Issue:18
| Discovery of Lu AA33810: a highly selective and potent NPY5 antagonist with in vivo efficacy in a model of mood disorder. |
| AID620876 | Inhibition of CYP2C9 | 2011 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 21, Issue:18
| Discovery of Lu AA33810: a highly selective and potent NPY5 antagonist with in vivo efficacy in a model of mood disorder. |
| AID620910 | Plasma concentration in cPP-induced feeding rat model at 30 mg/kg, po after 1 hr | 2011 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 21, Issue:18
| Discovery of Lu AA33810: a highly selective and potent NPY5 antagonist with in vivo efficacy in a model of mood disorder. |
| AID620923 | Antistress activity against chronic mild stress Sprague-Dawley rat model assessed as increase in sucrose consumption at 10 mg/kg, ip bid measured after 4 weeks | 2011 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 21, Issue:18
| Discovery of Lu AA33810: a highly selective and potent NPY5 antagonist with in vivo efficacy in a model of mood disorder. |
| AID620886 | Half life in Sprague-Dawley rat at 1 mg/kg, iv and 2 mg/kg, po by HPLC analysis | 2011 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 21, Issue:18
| Discovery of Lu AA33810: a highly selective and potent NPY5 antagonist with in vivo efficacy in a model of mood disorder. |
| AID620906 | Drug uptake in brain of cPP-induced feeding rat model at 10 mg/kg, po after 2 hrs | 2011 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 21, Issue:18
| Discovery of Lu AA33810: a highly selective and potent NPY5 antagonist with in vivo efficacy in a model of mood disorder. |
| AID620896 | Drug uptake in brain of cPP-induced feeding rat model at 3 mg/kg, po after 2 hrs | 2011 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 21, Issue:18
| Discovery of Lu AA33810: a highly selective and potent NPY5 antagonist with in vivo efficacy in a model of mood disorder. |
| AID620899 | Drug uptake in brain of cPP-induced feeding rat model at 3 mg/kg, po after 24 hrs | 2011 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 21, Issue:18
| Discovery of Lu AA33810: a highly selective and potent NPY5 antagonist with in vivo efficacy in a model of mood disorder. |
| AID620909 | Drug uptake in brain of cPP-induced feeding rat model at 10 mg/kg, po after 24 hrs | 2011 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 21, Issue:18
| Discovery of Lu AA33810: a highly selective and potent NPY5 antagonist with in vivo efficacy in a model of mood disorder. |
| AID620915 | Drug uptake in brain of cPP-induced feeding rat model at 30 mg/kg, po after 1 hr | 2011 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 21, Issue:18
| Discovery of Lu AA33810: a highly selective and potent NPY5 antagonist with in vivo efficacy in a model of mood disorder. |
| AID620875 | Inhibition of CYP1A2 | 2011 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 21, Issue:18
| Discovery of Lu AA33810: a highly selective and potent NPY5 antagonist with in vivo efficacy in a model of mood disorder. |
| AID620905 | Drug uptake in brain of cPP-induced feeding rat model at 10 mg/kg, po after 1 hr | 2011 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 21, Issue:18
| Discovery of Lu AA33810: a highly selective and potent NPY5 antagonist with in vivo efficacy in a model of mood disorder. |
| AID620883 | Plasma clearance in Sprague-Dawley rat at 1 mg/kg, iv and 2 mg/kg, po by HPLC analysis | 2011 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 21, Issue:18
| Discovery of Lu AA33810: a highly selective and potent NPY5 antagonist with in vivo efficacy in a model of mood disorder. |
| AID620861 | Antagonist activity at human NPY5 receptor assessed as calcium mobilization by FLIPR assay | 2011 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 21, Issue:18
| Discovery of Lu AA33810: a highly selective and potent NPY5 antagonist with in vivo efficacy in a model of mood disorder. |
| AID620881 | Efflux ratio of permeability from basolateral to apical side to apical to basolateral side in human Caco2 cells | 2011 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 21, Issue:18
| Discovery of Lu AA33810: a highly selective and potent NPY5 antagonist with in vivo efficacy in a model of mood disorder. |
| AID625644 | Plasma clearance in Sprague-Dawley rat at 2 mg/kg, po and 1 mg/kg, iv by HPLC method | 2011 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 21, Issue:21
| 5-(2'-Pyridyl)-2-aminothiazoles: alkyl amino sulfonamides and sulfamides as potent NPY(5) antagonists. |
| AID620888 | Inhibition of cPP-induced food intake in po dosed rat administered 1 to 24 hrs before cPP challenge measured for 1 hr | 2011 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 21, Issue:18
| Discovery of Lu AA33810: a highly selective and potent NPY5 antagonist with in vivo efficacy in a model of mood disorder. |
| AID620895 | Drug uptake in brain of cPP-induced feeding rat model at 3 mg/kg, po after 1 hr | 2011 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 21, Issue:18
| Discovery of Lu AA33810: a highly selective and potent NPY5 antagonist with in vivo efficacy in a model of mood disorder. |
| AID620894 | Plasma concentration in cPP-induced feeding rat model at 3 mg/kg, po after 24 hrs | 2011 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 21, Issue:18
| Discovery of Lu AA33810: a highly selective and potent NPY5 antagonist with in vivo efficacy in a model of mood disorder. |
| AID620918 | Drug uptake in brain of cPP-induced feeding rat model at 30 mg/kg, po after 6 hrs | 2011 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 21, Issue:18
| Discovery of Lu AA33810: a highly selective and potent NPY5 antagonist with in vivo efficacy in a model of mood disorder. |
| AID620872 | Plasma protein binding in rat | 2011 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 21, Issue:18
| Discovery of Lu AA33810: a highly selective and potent NPY5 antagonist with in vivo efficacy in a model of mood disorder. |
| AID620904 | Plasma concentration in cPP-induced feeding rat model at 10 mg/kg, po after 24 hrs | 2011 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 21, Issue:18
| Discovery of Lu AA33810: a highly selective and potent NPY5 antagonist with in vivo efficacy in a model of mood disorder. |
| AID620870 | Binding affinity to human 5HT1A receptor | 2011 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 21, Issue:18
| Discovery of Lu AA33810: a highly selective and potent NPY5 antagonist with in vivo efficacy in a model of mood disorder. |
| AID620882 | Oral bioavailability in Sprague-Dawley rat at 2 mg/kg by HPLC analysis | 2011 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 21, Issue:18
| Discovery of Lu AA33810: a highly selective and potent NPY5 antagonist with in vivo efficacy in a model of mood disorder. |
| AID620925 | Plasma clearance in mouse at 1 mg/kg, iv and 2 mg/kg, po by HPLC analysis | 2011 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 21, Issue:18
| Discovery of Lu AA33810: a highly selective and potent NPY5 antagonist with in vivo efficacy in a model of mood disorder. |
| AID620868 | Drug uptake in rat brain at 10 mg/kg, po after 4 hrs | 2011 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 21, Issue:18
| Discovery of Lu AA33810: a highly selective and potent NPY5 antagonist with in vivo efficacy in a model of mood disorder. |
| AID620892 | Plasma concentration in cPP-induced feeding rat model at 3 mg/kg, po after 4 hrs | 2011 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 21, Issue:18
| Discovery of Lu AA33810: a highly selective and potent NPY5 antagonist with in vivo efficacy in a model of mood disorder. |
| AID620897 | Drug uptake in brain of cPP-induced feeding rat model at 3 mg/kg, po after 4 hrs | 2011 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 21, Issue:18
| Discovery of Lu AA33810: a highly selective and potent NPY5 antagonist with in vivo efficacy in a model of mood disorder. |
| AID620900 | Plasma concentration in cPP-induced feeding rat model at 10 mg/kg, po after 1 hr | 2011 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 21, Issue:18
| Discovery of Lu AA33810: a highly selective and potent NPY5 antagonist with in vivo efficacy in a model of mood disorder. |
| AID620879 | Apparent permeability from apical to basolateral side of the human Caco2 cells | 2011 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 21, Issue:18
| Discovery of Lu AA33810: a highly selective and potent NPY5 antagonist with in vivo efficacy in a model of mood disorder. |
| AID620902 | Plasma concentration in cPP-induced feeding rat model at 10 mg/kg, po after 4 hrs | 2011 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 21, Issue:18
| Discovery of Lu AA33810: a highly selective and potent NPY5 antagonist with in vivo efficacy in a model of mood disorder. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |