| Assay ID | Title | Year | Journal | Article |
|---|
| AID1296008 | Cytotoxic Profiling of Annotated Libraries Using Quantitative High-Throughput Screening | 2020 | SLAS discovery : advancing life sciences R & D, 01, Volume: 25, Issue:1
| Cytotoxic Profiling of Annotated and Diverse Chemical Libraries Using Quantitative High-Throughput Screening. |
| AID1347159 | Primary screen GU Rhodamine qHTS for Zika virus inhibitors: Unlinked NS2B-NS3 protease assay | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1346987 | P-glycoprotein substrates identified in KB-8-5-11 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5
| A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
| AID1346986 | P-glycoprotein substrates identified in KB-3-1 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5
| A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
| AID1347160 | Primary screen NINDS Rhodamine qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1069744 | Agonist activity at recombinant GST-tagged RXRalpha LBD (unknown origin) assessed as induction of fluorescein labeled D22 coactivator recruitment after 4 hrs by TR-FRET assay relative to control | 2014 | Bioorganic & medicinal chemistry, Feb-15, Volume: 22, Issue:4
| Inhibition of IκB kinase-β and IκB kinase-α by heterocyclic adamantyl arotinoids. |
| AID1069747 | Antagonist activity at Gal4-fused RXRalpha (unknown origin) transfected in HEK293 cells assessed as CD3254-induced transcriptional activity at 4 uM by luciferase/beta-galactosidase reporter gene assay relative to CD3254-treated control | 2014 | Bioorganic & medicinal chemistry, Feb-15, Volume: 22, Issue:4
| Inhibition of IκB kinase-β and IκB kinase-α by heterocyclic adamantyl arotinoids. |
| AID1069748 | Antagonist activity at Gal4-fused RARalpha (unknown origin) transfected in HEK293 cells assessed as ATRA-induced transcriptional activity at 4 uM by luciferase/beta-galactosidase reporter gene assay relative to ATRA-treated control | 2014 | Bioorganic & medicinal chemistry, Feb-15, Volume: 22, Issue:4
| Inhibition of IκB kinase-β and IκB kinase-α by heterocyclic adamantyl arotinoids. |
| AID1069745 | Inverse agonist activity at RARalpha (unknown origin) | 2014 | Bioorganic & medicinal chemistry, Feb-15, Volume: 22, Issue:4
| Inhibition of IκB kinase-β and IκB kinase-α by heterocyclic adamantyl arotinoids. |
| AID1069749 | Agonist activity at Gal4-fused RXRalpha (unknown origin) transfected in HEK293 cells assessed as induction of transcriptional activity at 4 uM after 24 hrs by luciferase/beta-galactosidase reporter gene assay relative to control | 2014 | Bioorganic & medicinal chemistry, Feb-15, Volume: 22, Issue:4
| Inhibition of IκB kinase-β and IκB kinase-α by heterocyclic adamantyl arotinoids. |
| AID1069743 | Agonist activity at recombinant GST-tagged RXRalpha LBD (unknown origin) assessed as induction of biotinylated SRC-1-676-700 coactivator recruitment after 4 hrs by TR-FRET assay (Rvb = 148 +/- 7%) | 2014 | Bioorganic & medicinal chemistry, Feb-15, Volume: 22, Issue:4
| Inhibition of IκB kinase-β and IκB kinase-α by heterocyclic adamantyl arotinoids. |
| AID364889 | Antagonist activity at human RARbeta expressed in african green monkey CV1 cells assessed as all-trans-retinoic acid-stimulated Gal4 transactivation activity by luciferase reporter gene assay | 2008 | Journal of medicinal chemistry, Sep-11, Volume: 51, Issue:17
| Inhibition of IkappaB kinase-beta and anticancer activities of novel chalcone adamantyl arotinoids. |
| AID364691 | Antagonist activity at human RARalpha expressed in african green monkey CV1 cells assessed as all-trans-retinoic acid-stimulated Gal4 transactivation activity by luciferase reporter gene assay | 2008 | Journal of medicinal chemistry, Sep-11, Volume: 51, Issue:17
| Inhibition of IkappaB kinase-beta and anticancer activities of novel chalcone adamantyl arotinoids. |
| AID1069750 | Agonist activity at Gal4-fused RARalpha (unknown origin) transfected in HEK293 cells assessed as induction of transcriptional activity at 4 uM after 6 hrs by luciferase/beta-galactosidase reporter gene assay relative to control | 2014 | Bioorganic & medicinal chemistry, Feb-15, Volume: 22, Issue:4
| Inhibition of IκB kinase-β and IκB kinase-α by heterocyclic adamantyl arotinoids. |
| AID364890 | Antagonist activity at human RARgamma expressed in african green monkey CV1 cells assessed as all-trans-retinoic acid-stimulated Gal4 transactivation activity by luciferase reporter gene assay | 2008 | Journal of medicinal chemistry, Sep-11, Volume: 51, Issue:17
| Inhibition of IkappaB kinase-beta and anticancer activities of novel chalcone adamantyl arotinoids. |
| AID420861 | Inhibition of transactivation activity of Gal4-LBD fused human RARbeta (169 to 448) transfected in atRA-stimulated african green monkey CV1 cells after 6 hrs by Dual-light chemiluminescent assay | 2009 | European journal of medicinal chemistry, Jun, Volume: 44, Issue:6
| Highly twisted adamantyl arotinoids: synthesis, antiproliferative effects and RXR transactivation profiles. |
| AID420860 | Inhibition of transactivation activity of Gal4-LBD fused human RARgamma (178 to 454) transfected in atRA-stimulated african green monkey CV1 cells after 6 hrs by Dual-light chemiluminescent assay | 2009 | European journal of medicinal chemistry, Jun, Volume: 44, Issue:6
| Highly twisted adamantyl arotinoids: synthesis, antiproliferative effects and RXR transactivation profiles. |
| AID1346786 | Human Retinoic acid receptor-beta (1B. Retinoic acid receptors) | 2002 | Nature, Jan-10, Volume: 415, Issue:6868
| Co-regulator recruitment and the mechanism of retinoic acid receptor synergy. |
| AID1346740 | Human Retinoic acid receptor-alpha (1B. Retinoic acid receptors) | 2002 | Nature, Jan-10, Volume: 415, Issue:6868
| Co-regulator recruitment and the mechanism of retinoic acid receptor synergy. |
| AID1346788 | Human Retinoic acid receptor-gamma (1B. Retinoic acid receptors) | 2002 | Nature, Jan-10, Volume: 415, Issue:6868
| Co-regulator recruitment and the mechanism of retinoic acid receptor synergy. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |