| AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1
| High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID651635 | Viability Counterscreen for Primary qHTS for Inhibitors of ATXN expression | | | |
| AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1
| High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID1745845 | Primary qHTS for Inhibitors of ATXN expression | | | |
| AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1
| High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID504810 | Antagonists of the Thyroid Stimulating Hormone Receptor: HTS campaign | 2010 | Endocrinology, Jul, Volume: 151, Issue:7
| A small molecule inverse agonist for the human thyroid-stimulating hormone receptor. |
| AID504812 | Inverse Agonists of the Thyroid Stimulating Hormone Receptor: HTS campaign | 2010 | Endocrinology, Jul, Volume: 151, Issue:7
| A small molecule inverse agonist for the human thyroid-stimulating hormone receptor. |
| AID458662 | Inhibition of Clostridium botulinum toxin BoNT/A light chain | 2010 | Journal of medicinal chemistry, Mar-11, Volume: 53, Issue:5
| Synthesis and biological evaluation of botulinum neurotoxin a protease inhibitors. |
| AID582466 | Inhibition of protease activity of recombinant Clostridium botulinum BoNT/E light chain expressed in Escherichia coli (pET24a+/BL21(DE3)) assessed as cleavage of SNAP-25 at 240 uM after 30 mins by SDS-PAGE analysis | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8
| Identification and biochemical characterization of small-molecule inhibitors of Clostridium botulinum neurotoxin serotype A. |
| AID673914 | Inhibition of Clostridium botulinum Hall BoNT/A protease activity using Ac-SNKTRIDEANQRATKML-NH2 as substrate after 5 mins by RP-HPLC analysis | 2012 | ACS medicinal chemistry letters, May-10, Volume: 3, Issue:5
| Fungal bis-Naphthopyrones as Inhibitors of Botulinum Neurotoxin Serotype A. |
| AID582462 | Inhibition of protease activity of recombinant full-length Clostridium botulinum BoNT/B light chain at 20 uM after 5 mins by HPLC-based assay | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8
| Identification and biochemical characterization of small-molecule inhibitors of Clostridium botulinum neurotoxin serotype A. |
| AID582457 | Inhibition of zinc carboxypeptidase A at up to 20 uM | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8
| Identification and biochemical characterization of small-molecule inhibitors of Clostridium botulinum neurotoxin serotype A. |
| AID582465 | Inhibition of protease activity of recombinant Clostridium botulinum BoNT/A (1 to 425) light chain after 5 mins by HPLC-based assay | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8
| Identification and biochemical characterization of small-molecule inhibitors of Clostridium botulinum neurotoxin serotype A. |
| AID673915 | Inhibition of Clostridium botulinum Hall BoNT/A-mediated paralysis in CD1 mouse phrenic nerve hemidiaphragm assessed as time required to 50% loss of twitch tension at 20 uM measured upto 5 hrs (Rvb = 62 mins) | 2012 | ACS medicinal chemistry letters, May-10, Volume: 3, Issue:5
| Fungal bis-Naphthopyrones as Inhibitors of Botulinum Neurotoxin Serotype A. |
| AID582453 | Inhibition of Clostridium botulinum BoNT/A-mediated neuromuscular block in CD1 mouse phrenic nerve hemidiaphragm assessed as time required to 50% loss of twitch tension at 0.5 uM after 15 to 20 mins | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8
| Identification and biochemical characterization of small-molecule inhibitors of Clostridium botulinum neurotoxin serotype A. |
| AID673913 | Inhibition of Clostridium botulinum Hall BoNT/A protease activity using Ac-SNKTRIDEANQRATKML-NH2 as substrate at 20 uM after 5 mins by RP-HPLC analysis | 2012 | ACS medicinal chemistry letters, May-10, Volume: 3, Issue:5
| Fungal bis-Naphthopyrones as Inhibitors of Botulinum Neurotoxin Serotype A. |
| AID673916 | Inhibition of Clostridium botulinum Hall BoNT/A-mediated paralysis in CD1 mouse phrenic nerve hemidiaphragm assessed as time required to 50% loss of twitch tension at 2 uM measured upto 5 hrs (Rvb = 62 mins) | 2012 | ACS medicinal chemistry letters, May-10, Volume: 3, Issue:5
| Fungal bis-Naphthopyrones as Inhibitors of Botulinum Neurotoxin Serotype A. |
| AID582458 | Inhibition of Clostridium botulinum BoNT/A light chain-mediated SNAP-25 cleavage in mouse Neuro2a cells at 10 uM after 30 mins by Western blotting | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8
| Identification and biochemical characterization of small-molecule inhibitors of Clostridium botulinum neurotoxin serotype A. |
| AID673912 | Inhibition of Clostridium botulinum Hall BoNT/A protease activity using Ac-SNKTRIDEANQRATKML-NH2 as substrate at 100 uM after 5 mins by RP-HPLC analysis | 2012 | ACS medicinal chemistry letters, May-10, Volume: 3, Issue:5
| Fungal bis-Naphthopyrones as Inhibitors of Botulinum Neurotoxin Serotype A. |
| AID582464 | Inhibition of protease activity of recombinant full-length Clostridium botulinum BoNT/A light chain after 5 mins by HPLC-based assay | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8
| Identification and biochemical characterization of small-molecule inhibitors of Clostridium botulinum neurotoxin serotype A. |
| AID582459 | Inhibition of Clostridium botulinum BoNT/A light chain-mediated SNAP-25 cleavage in mouse Neuro2a cells at 15 uM after 30 mins by Western blotting | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8
| Identification and biochemical characterization of small-molecule inhibitors of Clostridium botulinum neurotoxin serotype A. |
| AID582460 | Inhibition of protease activity of recombinant full-length Clostridium botulinum BoNT/A light chain at 200 uM after 5 mins by HPLC-based assay | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8
| Identification and biochemical characterization of small-molecule inhibitors of Clostridium botulinum neurotoxin serotype A. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |