fluorenone oxime

Fluorenone oxime is a synthetic organic compound with a structure based on the fluorenone molecule, modified by the addition of an oxime group. It is a crystalline solid with a melting point of 157-159 °C.

Fluorenone oxime is typically synthesized by reacting fluorenone with hydroxylamine hydrochloride in the presence of a base. The reaction proceeds via nucleophilic attack of the hydroxylamine on the carbonyl group of fluorenone, followed by dehydration to form the oxime.

Fluorenone oxime is of interest to researchers for several reasons. It is a valuable precursor in the synthesis of other organic compounds, including various heterocycles and bioactive molecules. Moreover, it exhibits interesting pharmacological properties, such as anti-inflammatory and anticancer activities. These properties have led to ongoing research exploring its potential therapeutic applications.

The presence of the oxime group in fluorenone oxime allows for the formation of coordination complexes with metal ions. This property has been investigated in the development of sensors for metal ions, particularly for heavy metals like mercury and lead.

Furthermore, fluorenone oxime is studied for its photochemical properties. It exhibits photochromism, meaning it undergoes a reversible change in color upon exposure to ultraviolet light. This property makes it potentially useful in applications such as optical switching and data storage.'
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