Pancreatic alpha-amylase

An alpha-amylase 2A that is encoded in the genome of human. [PRO:DNx, UniProtKB:P04746]

PA;
EC 3.2.1.1;
1,4-alpha-D-glucan glucanohydrolase

Research

Drug	Taxonomy	Measurement	Average (mM)	Bioassay(s)	Publication(s)
cholecystokinin (27-33), tert-butyloxycarbonyl-nle(28,31)-	Homo sapiens (human)	EC50	0.0000	1	1

This protein enables 3 target(s):

Target	Category	Definition
alpha-amylase activity	molecular function	Catalysis of the endohydrolysis of (1->4)-alpha-D-glucosidic linkages in polysaccharides containing three or more alpha-(1->4)-linked D-glucose units. [PMID:12527308]
calcium ion binding	molecular function	Binding to a calcium ion (Ca2+). [GOC:ai]
chloride ion binding	molecular function	Binding to a chloride ion (Cl-). [GOC:mah]

This protein is located in 3 target(s):

Target	Category	Definition
extracellular region	cellular component	The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite. [GOC:go_curators]
extracellular space	cellular component	That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid. [ISBN:0198547684]
extracellular exosome	cellular component	A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm. [GOC:BHF, GOC:mah, GOC:vesicles, PMID:15908444, PMID:17641064, PMID:19442504, PMID:19498381, PMID:22418571, PMID:24009894]

This protein is active in 1 target(s):

Target	Category	Definition
extracellular space	cellular component	That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid. [ISBN:0198547684]

This protein is involved in 3 target(s):

Target	Category	Definition
carbohydrate catabolic process	biological process	The chemical reactions and pathways resulting in the breakdown of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. [ISBN:0198506732]
polysaccharide digestion	biological process	The whole of the physical, chemical, and biochemical processes carried out by living organisms to break down ingested polysaccharides into components that may be easily absorbed and directed into metabolism. [GOC:go_curators]
carbohydrate metabolic process	biological process	The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. [GOC:mah, ISBN:0198506732]