| Assay ID | Title | Year | Journal | Article |
|---|
| AID48398 | Effect of 10 mM of GSH on the inhibitory activity of compound against Cathepsin K, at pH 5.5 | 2001 | Journal of medicinal chemistry, Jan-04, Volume: 44, Issue:1
| Novel, nonpeptidic cyanamides as potent and reversible inhibitors of human cathepsins K and L. |
| AID48405 | Inhibition of Cathepsin K at pH 7 | 2001 | Journal of medicinal chemistry, Jan-04, Volume: 44, Issue:1
| Novel, nonpeptidic cyanamides as potent and reversible inhibitors of human cathepsins K and L. |
| AID51224 | Inhibitory activity tested against Human Cathepsin L using Z-Phe-Arg-pNA as substrate | 2001 | Journal of medicinal chemistry, Jan-04, Volume: 44, Issue:1
| Novel, nonpeptidic cyanamides as potent and reversible inhibitors of human cathepsins K and L. |
| AID48399 | Effect of 10 mM of GSH on the inhibitory activity against Cathepsin K, at pH 7 | 2001 | Journal of medicinal chemistry, Jan-04, Volume: 44, Issue:1
| Novel, nonpeptidic cyanamides as potent and reversible inhibitors of human cathepsins K and L. |
| AID1553480 | Half life of the compound | 2019 | Journal of medicinal chemistry, 06-27, Volume: 62, Issue:12
| Emerging and Re-Emerging Warheads for Targeted Covalent Inhibitors: Applications in Medicinal Chemistry and Chemical Biology. |
| AID48404 | Inhibition of Cathepsin K at pH 5.5 | 2001 | Journal of medicinal chemistry, Jan-04, Volume: 44, Issue:1
| Novel, nonpeptidic cyanamides as potent and reversible inhibitors of human cathepsins K and L. |
| AID570622 | Inhibition of human recombinant cathepsin C after 1 hr | 2011 | ACS medicinal chemistry letters, Feb-10, Volume: 2, Issue:2
| Discovery of novel cyanamide-based inhibitors of cathepsin C. |
| AID241950 | Inhibitory concentration against human cathepsin K using 10 uM Cbz-Phe-Arg-AMC | 2005 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 15, Issue:7
| Novel and potent cyclic cyanamide-based cathepsin K inhibitors. |
| AID570624 | Inhibition of human recombinant cathepsin B after 1 hr | 2011 | ACS medicinal chemistry letters, Feb-10, Volume: 2, Issue:2
| Discovery of novel cyanamide-based inhibitors of cathepsin C. |
| AID1170688 | GSH reactivity assessed as reaction half life through transition state modeling at pH 7.4 | 2014 | Journal of medicinal chemistry, Dec-11, Volume: 57, Issue:23
| Chemical and computational methods for the characterization of covalent reactive groups for the prospective design of irreversible inhibitors. |
| AID1170692 | Reactivity of covalent reactive group using GSH reaction assessed as pseudo-first-order reaction at 37 degC by nuclear magnetic resonance spectroscopy | 2014 | Journal of medicinal chemistry, Dec-11, Volume: 57, Issue:23
| Chemical and computational methods for the characterization of covalent reactive groups for the prospective design of irreversible inhibitors. |
| AID570623 | Inhibition of human recombinant cathepsin K after 1 hr | 2011 | ACS medicinal chemistry letters, Feb-10, Volume: 2, Issue:2
| Discovery of novel cyanamide-based inhibitors of cathepsin C. |
| AID570627 | Metabolic stability in rat plasma assessed as compound remaining after 30 mins by HPLC analysis | 2011 | ACS medicinal chemistry letters, Feb-10, Volume: 2, Issue:2
| Discovery of novel cyanamide-based inhibitors of cathepsin C. |
| AID570626 | Inhibition of human recombinant cathepsin S after 1 hr | 2011 | ACS medicinal chemistry letters, Feb-10, Volume: 2, Issue:2
| Discovery of novel cyanamide-based inhibitors of cathepsin C. |
| AID570625 | Inhibition of human recombinant cathepsin L after 1 hr | 2011 | ACS medicinal chemistry letters, Feb-10, Volume: 2, Issue:2
| Discovery of novel cyanamide-based inhibitors of cathepsin C. |
| AID238235 | Inhibition constant against human cathepsin K | 2005 | Bioorganic & medicinal chemistry letters, Jun-15, Volume: 15, Issue:12
| Acyclic cyanamide-based inhibitors of cathepsin K. |
| AID50270 | Inhibitory activity tested against Human Cathepsin B using Z-Phe-Arg-pNA as substrate | 2001 | Journal of medicinal chemistry, Jan-04, Volume: 44, Issue:1
| Novel, nonpeptidic cyanamides as potent and reversible inhibitors of human cathepsins K and L. |
| AID48411 | Inhibitory activity tested against Human Cathepsin K using Z-Phe-Arg-pNA as substrate | 2001 | Journal of medicinal chemistry, Jan-04, Volume: 44, Issue:1
| Novel, nonpeptidic cyanamides as potent and reversible inhibitors of human cathepsins K and L. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |