| Assay ID | Title | Year | Journal | Article |
|---|
| AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1
| High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID651635 | Viability Counterscreen for Primary qHTS for Inhibitors of ATXN expression | | | |
| AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1
| High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1
| High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID504812 | Inverse Agonists of the Thyroid Stimulating Hormone Receptor: HTS campaign | 2010 | Endocrinology, Jul, Volume: 151, Issue:7
| A small molecule inverse agonist for the human thyroid-stimulating hormone receptor. |
| AID1745845 | Primary qHTS for Inhibitors of ATXN expression | | | |
| AID504810 | Antagonists of the Thyroid Stimulating Hormone Receptor: HTS campaign | 2010 | Endocrinology, Jul, Volume: 151, Issue:7
| A small molecule inverse agonist for the human thyroid-stimulating hormone receptor. |
| AID1187647 | Permeability of the compound at donor pH 5.0 and acceptor pH 7.4 by PAMPA | 2014 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 24, Issue:17
| Design, synthesis and evaluation of benzoisothiazolones as selective inhibitors of PHOSPHO1. |
| AID1187644 | Aqueous solubility of the compound in pH 5 pION buffer by UV kinetic solubility method | 2014 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 24, Issue:17
| Design, synthesis and evaluation of benzoisothiazolones as selective inhibitors of PHOSPHO1. |
| AID1187658 | Metabolic stability in mouse plasma assessed as compound remaining at 1:1 1 x pH7.4 PBS measured at 3 hrs by LC-MS/MS analysis | 2014 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 24, Issue:17
| Design, synthesis and evaluation of benzoisothiazolones as selective inhibitors of PHOSPHO1. |
| AID1187643 | Inhibition of PMM2 (unknown origin) | 2014 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 24, Issue:17
| Design, synthesis and evaluation of benzoisothiazolones as selective inhibitors of PHOSPHO1. |
| AID1187642 | Inhibition of phosphomannose isomerase (unknown origin) | 2014 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 24, Issue:17
| Design, synthesis and evaluation of benzoisothiazolones as selective inhibitors of PHOSPHO1. |
| AID1187656 | Metabolic stability in human plasma assessed as compound remaining at 1:1 1 x pH7.4 PBS measured at 3 hrs by LC-MS/MS analysis | 2014 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 24, Issue:17
| Design, synthesis and evaluation of benzoisothiazolones as selective inhibitors of PHOSPHO1. |
| AID1187649 | Permeability of the compound at donor pH 7.4 and acceptor pH 7.4 by PAMPA | 2014 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 24, Issue:17
| Design, synthesis and evaluation of benzoisothiazolones as selective inhibitors of PHOSPHO1. |
| AID1187657 | Metabolic stability in mouse plasma assessed as compound remaining at 1 x pH7.4 PBS measured at 3 hrs by LC-MS/MS analysis | 2014 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 24, Issue:17
| Design, synthesis and evaluation of benzoisothiazolones as selective inhibitors of PHOSPHO1. |
| AID1187659 | Metabolic stability in human liver microsomes measured at 1 uM after 1 hr at pH 7.4 by LC-MS/MS analysis | 2014 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 24, Issue:17
| Design, synthesis and evaluation of benzoisothiazolones as selective inhibitors of PHOSPHO1. |
| AID1187661 | Metabolic stability in mouse liver microsomes measured at 1 uM after 1 hr at pH 7.4 by LC-MS/MS analysis | 2014 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 24, Issue:17
| Design, synthesis and evaluation of benzoisothiazolones as selective inhibitors of PHOSPHO1. |
| AID1187641 | Inhibition of PHOSPHO1 phosphoethanolamine activity (unknown origin) assessed as amount of inorganic phosphate release after 30 mins | 2014 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 24, Issue:17
| Design, synthesis and evaluation of benzoisothiazolones as selective inhibitors of PHOSPHO1. |
| AID1187645 | Aqueous solubility of the compound in pH 6.2 pION buffer by UV kinetic solubility method | 2014 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 24, Issue:17
| Design, synthesis and evaluation of benzoisothiazolones as selective inhibitors of PHOSPHO1. |
| AID1187655 | Metabolic stability in human plasma assessed as compound remaining at 1 x pH7.4 PBS measured at 3 hrs by LC-MS/MS analysis | 2014 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 24, Issue:17
| Design, synthesis and evaluation of benzoisothiazolones as selective inhibitors of PHOSPHO1. |
| AID1187646 | Aqueous solubility of the compound in pH 7.4 pION buffer by UV kinetic solubility method | 2014 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 24, Issue:17
| Design, synthesis and evaluation of benzoisothiazolones as selective inhibitors of PHOSPHO1. |
| AID1187651 | Plasma protein binding in human at 10 uM by LC-MS analysis | 2014 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 24, Issue:17
| Design, synthesis and evaluation of benzoisothiazolones as selective inhibitors of PHOSPHO1. |
| AID1187653 | Plasma protein binding in mouse at 10 uM by LC-MS analysis | 2014 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 24, Issue:17
| Design, synthesis and evaluation of benzoisothiazolones as selective inhibitors of PHOSPHO1. |
| AID1187648 | Permeability of the compound at donor pH 6.2 and acceptor pH 7.4 by PAMPA | 2014 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 24, Issue:17
| Design, synthesis and evaluation of benzoisothiazolones as selective inhibitors of PHOSPHO1. |
| AID1187652 | Plasma protein binding in mouse at 1 uM by LC-MS analysis | 2014 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 24, Issue:17
| Design, synthesis and evaluation of benzoisothiazolones as selective inhibitors of PHOSPHO1. |
| AID1187654 | Cytotoxicity against human Fa2N-4 cells after 24 hrs by ATP-lite 1-step assay | 2014 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 24, Issue:17
| Design, synthesis and evaluation of benzoisothiazolones as selective inhibitors of PHOSPHO1. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |