| Assay ID | Title | Year | Journal | Article |
|---|
| AID1142838 | Inhibition of Helicobacter pylori carbonic anhydrase by stopped-flow CO2 hydration assay | 2014 | Bioorganic & medicinal chemistry, Jun-01, Volume: 22, Issue:11
| Sulfonamide inhibition studies of two β-carbonic anhydrases from the bacterial pathogen Legionella pneumophila. |
| AID552131 | Inhibition of Stylophora pistillata carbonic anhydrase 2 by stopped-flow CO2 hydration assay | 2011 | Bioorganic & medicinal chemistry letters, Jan-15, Volume: 21, Issue:2
| Carbonic anhydrase inhibitors. Inhibition studies with anions and sulfonamides of a new cytosolic enzyme from the scleractinian coral Stylophora pistillata. |
| AID320314 | Inhibition of human catalytic domain carbonic hydrase 12 by stopped-flow CO2 hydration assay | 2008 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 18, Issue:3
| Carbonic anhydrase inhibitors. Interaction of 2-N,N-dimethylamino-1,3,4-thiadiazole-5-methanesulfonamide with 12 mammalian isoforms: kinetic and X-ray crystallographic studies. |
| AID1628036 | Inhibition of full length human cytosolic carbonic anhydrase 1 preincubated for 15 mins by stop flow CO2 hydrase assay | 2016 | Bioorganic & medicinal chemistry letters, 09-01, Volume: 26, Issue:17
| Cloning, expression, purification and sulfonamide inhibition profile of the complete domain of the η-carbonic anhydrase from Plasmodium falciparum. |
| AID369275 | Inhibition of mouse recombinant carbonic anhydrase 15 by stopped flow CO2 hydrase assay | 2009 | Journal of medicinal chemistry, Feb-12, Volume: 52, Issue:3
| Cloning, expression, post-translational modifications and inhibition studies on the latest mammalian carbonic anhydrase isoform, CA XV. |
| AID493891 | Inhibition of human recombinant carbonic anhydrase 9 after 15 mins by stopped-flow CO2 hydration assay | 2010 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 20, Issue:15
| Carbonic anhydrase inhibitors. The X-ray crystal structure of human isoform II in adduct with an adamantyl analogue of acetazolamide resides in a less utilized binding pocket than most hydrophobic inhibitors. |
| AID1188136 | Inhibition of Helicobacter pylori Beta-carbonic anhydrase compound preincubated for 15 mins by stopped flow CO2 hydrase assay method | 2014 | Bioorganic & medicinal chemistry, Sep-01, Volume: 22, Issue:17
| Sulfonamide inhibition study of the carbonic anhydrases from the bacterial pathogen Porphyromonas gingivalis: the β-class (PgiCAb) versus the γ-class (PgiCA) enzymes. |
| AID1434430 | Inhibition of Vibrio cholerae Gamma-carbonic anhydrase assessed as reduction in CO2 hydration preincubated for 15 mins followed by CO2 addition measured for 10 to 100 sec by Line-Weaver Burk plot analysis | | | |
| AID349606 | Inhibition of human recombinant carbonic anhydrase 2 by stopped flow CO2 hydration assay | 2009 | Journal of medicinal chemistry, May-14, Volume: 52, Issue:9
| Carbonic anhydrase inhibitors. Cloning, characterization, and inhibition studies of a new beta-carbonic anhydrase from Mycobacterium tuberculosis. |
| AID320306 | Inhibition of human recombinant full length carbonic hydrase 2 by stopped-flow CO2 hydration assay | 2008 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 18, Issue:3
| Carbonic anhydrase inhibitors. Interaction of 2-N,N-dimethylamino-1,3,4-thiadiazole-5-methanesulfonamide with 12 mammalian isoforms: kinetic and X-ray crystallographic studies. |
| AID243090 | Ratio of inhibition of carbonic anhydrase IV in human to that of carbonic anhydrase IV in bovine | 2005 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 15, Issue:4
| Carbonic anhydrase inhibitors. Inhibition of the membrane-bound human and bovine isozymes IV with sulfonamides. |
| AID437749 | Inhibition of human recombinant CA2 by stopped-flow hydration assay | 2009 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 19, Issue:23
| Carbonic anhydrase inhibitors. Characterization and inhibition studies of the most active beta-carbonic anhydrase from Mycobacterium tuberculosis, Rv3588c. |
| AID239240 | Inhibitory potency against human cloned Carbonic anhydrase II expressed in Escherichia coli strain BL21 | 2005 | Bioorganic & medicinal chemistry letters, Jan-17, Volume: 15, Issue:2
| Carbonic anhydrase inhibitors. Novel sulfanilamide/acetazolamide derivatives obtained by the tail approach and their interaction with the cytosolic isozymes I and II, and the tumor-associated isozyme IX. |
| AID238574 | Inhibitory activity against human carbonic anhydrase II (hCAII) | 2005 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 15, Issue:4
| Carbonic anhydrase inhibitors. Inhibition of the membrane-bound human and bovine isozymes IV with sulfonamides. |
| AID568362 | Inhibition of human carbonic anhydrase 1 preincubated for 15 mins by CO2 hydration stopped-flow assay | 2011 | Bioorganic & medicinal chemistry, Feb-15, Volume: 19, Issue:4
| Kinetic and docking studies of phenol-based inhibitors of carbonic anhydrase isoforms I, II, IX and XII evidence a new binding mode within the enzyme active site. |
| AID1453411 | Inhibition of Burkholderia pseudomallei beta-carbonic anhydrase assessed as reduction in CO2 hydration preincubated for 15 mins followed by CO2 addition measured for 10 to 100 secs by stopped-flow assay | | | |
| AID436564 | Inhibition of human recombinant CA2 by stopped-flow CO2 assay | 2009 | Bioorganic & medicinal chemistry, Jul-15, Volume: 17, Issue:14
| Carbonic anhydrase inhibitors. Inhibition studies of a coral secretory isoform by sulfonamides. |
| AID778725 | Inhibition of recombinant Leishmania donovani chagasi beta-carbonic anhydrase expressed in baculovirus infected insect Sf9 cells incubated for 15 mins prior to testing by stopped flow CO2 hydrase assay | 2013 | Journal of medicinal chemistry, Sep-26, Volume: 56, Issue:18
| Cloning, characterization, and inhibition studies of a β-carbonic anhydrase from Leishmania donovani chagasi, the protozoan parasite responsible for leishmaniasis. |
| AID1240214 | Inhibition of Nostoc commune gamma carbonic anhydrase by CO2 hydration assay | 2015 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 25, Issue:17
| Sulfonamide inhibition studies of the γ-carbonic anhydrase from the Antarctic bacterium Pseudoalteromonas haloplanktis. |
| AID1275910 | Inhibition of Vibrio cholerae beta-carbonic anhydrase using CO2 as substrate preincubated for 15 mins by stopped-flow CO2 hydration assay | 2016 | Bioorganic & medicinal chemistry, Mar-01, Volume: 24, Issue:5
| Sulfonamide inhibition studies of the β-carbonic anhydrase from the pathogenic bacterium Vibrio cholerae. |
| AID743514 | Inhibition of human recombinant carbonic anhydrase 2 preincubated for 15 mins by CO2 hydration stopped-flow assay | 2013 | Bioorganic & medicinal chemistry, Mar-15, Volume: 21, Issue:6
| The alpha-carbonic anhydrase from the thermophilic bacterium Sulfurihydrogenibium yellowstonense YO3AOP1 is highly susceptible to inhibition by sulfonamides. |
| AID493888 | Inhibition of human recombinant carbonic anhydrase 5b after 15 mins by stopped-flow CO2 hydration assay | 2010 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 20, Issue:15
| Carbonic anhydrase inhibitors. The X-ray crystal structure of human isoform II in adduct with an adamantyl analogue of acetazolamide resides in a less utilized binding pocket than most hydrophobic inhibitors. |
| AID577531 | Inhibition of Brucella suis carbonic anhydrase I by spectrophotometry at pH 8.3 | 2011 | Bioorganic & medicinal chemistry, Feb-01, Volume: 19, Issue:3
| A new β-carbonic anhydrase from Brucella suis, its cloning, characterization, and inhibition with sulfonamides and sulfamates, leading to impaired pathogen growth. |
| AID427124 | Inhibition of Helicobacter pylori beta-carbonic anhydrase by stopped-flow CO2 hydration assay | 2009 | Bioorganic & medicinal chemistry, Jul-01, Volume: 17, Issue:13
| Carbonic anhydrase inhibitors. Inhibition and homology modeling studies of the fungal beta-carbonic anhydrase from Candida albicans with sulfonamides. |
| AID350901 | Inhibition of esterase activity of human carbonic anhydrase 1 by CO2 hydration method | 2009 | Bioorganic & medicinal chemistry, May-01, Volume: 17, Issue:9
| Effects of new 5-amino-1,3,4-thiadiazole-2-sulfonamide derivatives on human carbonic anhydrase isozymes. |
| AID669119 | Inhibition of GST-tagged Malassezia globosa ATCC 96807/CBS 7966 MG-CA expressed in Escherichia coli BL21(DE3) cells preincubated for 15 mins measured for 10 to 100 sec by stopped-flow method | 2012 | Journal of medicinal chemistry, Apr-12, Volume: 55, Issue:7
| Molecular cloning, characterization, and inhibition studies of a β-carbonic anhydrase from Malassezia globosa, a potential antidandruff target. |
| AID537657 | Inhibition of human carbonic anhydrase 2 by Lineweaver-Burke plot analysis | 2010 | European journal of medicinal chemistry, Nov, Volume: 45, Issue:11
| Synthesis, characterization and antiglaucoma activity of some novel pyrazole derivatives of 5-amino-1,3,4-thiadiazole-2-sulfonamide. |
| AID320309 | Inhibition of human recombinant full length carbonic hydrase 5A by stopped-flow CO2 hydration assay | 2008 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 18, Issue:3
| Carbonic anhydrase inhibitors. Interaction of 2-N,N-dimethylamino-1,3,4-thiadiazole-5-methanesulfonamide with 12 mammalian isoforms: kinetic and X-ray crystallographic studies. |
| AID1061068 | Inhibition of Leishmania donovani chagasi recombinant beta-carbonic anhydrase preincubated for 15 mins by stopped flow CO2 hydration assay | 2014 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 24, Issue:1
| Sulfonamide inhibition studies of the δ-carbonic anhydrase from the diatom Thalassiosira weissflogii. |
| AID1142833 | Inhibition of human carbonic anhydrase-1 by stopped-flow CO2 hydration assay | 2014 | Bioorganic & medicinal chemistry, Jun-01, Volume: 22, Issue:11
| Sulfonamide inhibition studies of two β-carbonic anhydrases from the bacterial pathogen Legionella pneumophila. |
| AID1195369 | Inhibition of human carbonic anhydrase 1 pre-incubated for 15 mins by stopped-flow CO2 hydration assay | 2015 | Bioorganic & medicinal chemistry, May-15, Volume: 23, Issue:10
| The β-carbonic anhydrase from the malaria mosquito Anopheles gambiae is highly inhibited by sulfonamides. |
| AID414961 | Inhibition of Mycobacterium tuberculosis H37Rv recombinant beta-carbonic anhydrase 1 expressed in Escherichia coli BL21 by stopped flow CO2 hydration method | 2009 | Journal of medicinal chemistry, Apr-23, Volume: 52, Issue:8
| Molecular cloning, characterization, and inhibition studies of the Rv1284 beta-carbonic anhydrase from Mycobacterium tuberculosis with sulfonamides and a sulfamate. |
| AID320312 | Inhibition of human recombinant full length carbonic hydrase 7 by stopped-flow CO2 hydration assay | 2008 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 18, Issue:3
| Carbonic anhydrase inhibitors. Interaction of 2-N,N-dimethylamino-1,3,4-thiadiazole-5-methanesulfonamide with 12 mammalian isoforms: kinetic and X-ray crystallographic studies. |
| AID320313 | Inhibition of human catalytic domain carbonic hydrase 9 by stopped-flow CO2 hydration assay | 2008 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 18, Issue:3
| Carbonic anhydrase inhibitors. Interaction of 2-N,N-dimethylamino-1,3,4-thiadiazole-5-methanesulfonamide with 12 mammalian isoforms: kinetic and X-ray crystallographic studies. |
| AID1142834 | Inhibition of human carbonic anhydrase-2 by stopped-flow CO2 hydration assay | 2014 | Bioorganic & medicinal chemistry, Jun-01, Volume: 22, Issue:11
| Sulfonamide inhibition studies of two β-carbonic anhydrases from the bacterial pathogen Legionella pneumophila. |
| AID577530 | Inhibition of Brucella suis carbonic anhydrase II by spectrophotometry at pH 8.3 | 2011 | Bioorganic & medicinal chemistry, Feb-01, Volume: 19, Issue:3
| A new β-carbonic anhydrase from Brucella suis, its cloning, characterization, and inhibition with sulfonamides and sulfamates, leading to impaired pathogen growth. |
| AID320305 | Inhibition of human recombinant full length carbonic hydrase 1 by stopped-flow CO2 hydration assay | 2008 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 18, Issue:3
| Carbonic anhydrase inhibitors. Interaction of 2-N,N-dimethylamino-1,3,4-thiadiazole-5-methanesulfonamide with 12 mammalian isoforms: kinetic and X-ray crystallographic studies. |
| AID261581 | Inhibition of Helicobacter pylori recombinant carbonic anhydrase by stopped-flow CO2 hydrase assay | 2006 | Journal of medicinal chemistry, Mar-23, Volume: 49, Issue:6
| Carbonic anhydrase inhibitors: DNA cloning and inhibition studies of the alpha-carbonic anhydrase from Helicobacter pylori, a new target for developing sulfonamide and sulfamate gastric drugs. |
| AID320308 | Inhibition of human recombinant full length carbonic hydrase 4 by stopped-flow CO2 hydration assay | 2008 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 18, Issue:3
| Carbonic anhydrase inhibitors. Interaction of 2-N,N-dimethylamino-1,3,4-thiadiazole-5-methanesulfonamide with 12 mammalian isoforms: kinetic and X-ray crystallographic studies. |
| AID263638 | Inhibition of Helicobacter pylori recombinant CA | 2006 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 16, Issue:8
| Carbonic anhydrase inhibitors: cloning and sulfonamide inhibition studies of a carboxyterminal truncated alpha-carbonic anhydrase from Helicobacter pylori. |
| AID427123 | Inhibition of Cryptococcus neoformans recombinant Can2 by stopped-flow CO2 hydration assay | 2009 | Bioorganic & medicinal chemistry, Jul-01, Volume: 17, Issue:13
| Carbonic anhydrase inhibitors. Inhibition and homology modeling studies of the fungal beta-carbonic anhydrase from Candida albicans with sulfonamides. |
| AID1194026 | Inhibition of recombinant Methanosarcina thermophila gamma-carbonic anhydrase by stopped flow CO2 hydrase assay | 2015 | Bioorganic & medicinal chemistry, Apr-15, Volume: 23, Issue:8
| Sulfonamide inhibition studies of the γ-carbonic anhydrase from the Antarctic cyanobacterium Nostoc commune. |
| AID299243 | Inhibition of human carbonic anhydrase 2 by stopped-flow CO2 hydrase assay | 2007 | Bioorganic & medicinal chemistry letters, Jul-01, Volume: 17, Issue:13
| Carbonic anhydrase inhibitors: the beta-carbonic anhydrase from Helicobacter pylori is a new target for sulfonamide and sulfamate inhibitors. |
| AID1194025 | Inhibition of human recombinant carbonic anhydrase 2 by stopped flow CO2 hydrase assay | 2015 | Bioorganic & medicinal chemistry, Apr-15, Volume: 23, Issue:8
| Sulfonamide inhibition studies of the γ-carbonic anhydrase from the Antarctic cyanobacterium Nostoc commune. |
| AID743512 | Inhibition of Sulfurihydrogenibium yellowstonense YO3AOP1 recombinant carbonic anhydrase preincubated for 15 mins by CO2 hydration stopped-flow assay | 2013 | Bioorganic & medicinal chemistry, Mar-15, Volume: 21, Issue:6
| The alpha-carbonic anhydrase from the thermophilic bacterium Sulfurihydrogenibium yellowstonense YO3AOP1 is highly susceptible to inhibition by sulfonamides. |
| AID238300 | Ki value against human carbonic anhydrase II (hCA II) | 2005 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 15, Issue:4
| Carbonic anhydrase inhibitors. Inhibition of the transmembrane isozyme XII with sulfonamides-a new target for the design of antitumor and antiglaucoma drugs? |
| AID222127 | Inhibition of cloned isozyme, human carbonic anhydrase IV | 2001 | Bioorganic & medicinal chemistry letters, Feb-26, Volume: 11, Issue:4
| Carbonic anhydrase inhibitors: synthesis of sulfonamides incorporating dtpa tails and of their zinc complexes with powerful topical antiglaucoma properties. |
| AID1278409 | Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by CO2 hydrase stopped flow assay | 2016 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 26, Issue:4
| Sulfonamide inhibition studies of the γ-carbonic anhydrase from the Antarctic bacterium Colwellia psychrerythraea. |
| AID299250 | Inhibition of Helicobacter pylori beta carbonic anhydrase by stopped-flow CO2 hydrase assay | 2007 | Bioorganic & medicinal chemistry letters, Jul-01, Volume: 17, Issue:13
| Carbonic anhydrase inhibitors: the beta-carbonic anhydrase from Helicobacter pylori is a new target for sulfonamide and sulfamate inhibitors. |
| AID47901 | Inhibitory activity against Human carbonic anhydrase II | 2002 | Journal of medicinal chemistry, Mar-28, Volume: 45, Issue:7
| Carbonic anhydrase inhibitors. A general approach for the preparation of water-soluble sulfonamides incorporating polyamino-polycarboxylate tails and of their metal complexes possessing long-lasting, topical intraocular pressure-lowering properties. |
| AID497130 | Selectivity ratio of Ki for wild type human recombinant carbonic anhydrase 1 to Ki for human recombinant carbonic anhydrase 1 Phe91Asn mutant | 2010 | Bioorganic & medicinal chemistry, Aug-01, Volume: 18, Issue:15
| Mutation of Phe91 to Asn in human carbonic anhydrase I unexpectedly enhanced both catalytic activity and affinity for sulfonamide inhibitors. |
| AID367821 | Inhibition of human recombinant CA2 by stopped-flow CO2 hydrase assay | 2009 | Bioorganic & medicinal chemistry, Feb-01, Volume: 17, Issue:3
| Carbonic anhydrase inhibitors: inhibition of the beta-class enzyme from the yeast Saccharomyces cerevisiae with sulfonamides and sulfamates. |
| AID497127 | Inhibition of wild type human recombinant carbonic anhydrase 1 expressed in Escherichia coli BL21 (DE3) after 15 mins by CO2 hydration method | 2010 | Bioorganic & medicinal chemistry, Aug-01, Volume: 18, Issue:15
| Mutation of Phe91 to Asn in human carbonic anhydrase I unexpectedly enhanced both catalytic activity and affinity for sulfonamide inhibitors. |
| AID1275912 | Inhibition of human Carbonic anhydrase2 using CO2 as substrate preincubated for 15 mins by stopped-flow CO2 hydration assay | 2016 | Bioorganic & medicinal chemistry, Mar-01, Volume: 24, Issue:5
| Sulfonamide inhibition studies of the β-carbonic anhydrase from the pathogenic bacterium Vibrio cholerae. |
| AID320316 | Inhibition of human recombinant full length carbonic hydrase 14 by stopped-flow CO2 hydration assay | 2008 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 18, Issue:3
| Carbonic anhydrase inhibitors. Interaction of 2-N,N-dimethylamino-1,3,4-thiadiazole-5-methanesulfonamide with 12 mammalian isoforms: kinetic and X-ray crystallographic studies. |
| AID493892 | Inhibition of human recombinant carbonic anhydrase 12 after 15 mins by stopped-flow CO2 hydration assay | 2010 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 20, Issue:15
| Carbonic anhydrase inhibitors. The X-ray crystal structure of human isoform II in adduct with an adamantyl analogue of acetazolamide resides in a less utilized binding pocket than most hydrophobic inhibitors. |
| AID275809 | Inhibition of catalytic domain of human recombinant CA IX | 2007 | Journal of medicinal chemistry, Jan-25, Volume: 50, Issue:2
| Carbonic anhydrase inhibitors. DNA cloning, characterization, and inhibition studies of the human secretory isoform VI, a new target for sulfonamide and sulfamate inhibitors. |
| AID743513 | Inhibition of Helicobacter pylori recombinant alpha carbonic anhydrase preincubated for 15 mins by CO2 hydration stopped-flow assay | 2013 | Bioorganic & medicinal chemistry, Mar-15, Volume: 21, Issue:6
| The alpha-carbonic anhydrase from the thermophilic bacterium Sulfurihydrogenibium yellowstonense YO3AOP1 is highly susceptible to inhibition by sulfonamides. |
| AID48300 | Inhibitory activity against human cloned carbonic anhydrase isozyme IX, by CO2 hydrase assay method. | 2003 | Bioorganic & medicinal chemistry letters, Mar-24, Volume: 13, Issue:6
| Carbonic anhydrase inhibitors: inhibition of the tumor-associated isozyme IX with aromatic and heterocyclic sulfonamides. |
| AID493894 | Inhibition of human recombinant carbonic anhydrase 14 after 15 mins by stopped-flow CO2 hydration assay | 2010 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 20, Issue:15
| Carbonic anhydrase inhibitors. The X-ray crystal structure of human isoform II in adduct with an adamantyl analogue of acetazolamide resides in a less utilized binding pocket than most hydrophobic inhibitors. |
| AID1195370 | Inhibition of human carbonic anhydrase 2 pre-incubated for 15 mins by stopped-flow CO2 hydration assay | 2015 | Bioorganic & medicinal chemistry, May-15, Volume: 23, Issue:10
| The β-carbonic anhydrase from the malaria mosquito Anopheles gambiae is highly inhibited by sulfonamides. |
| AID238597 | Inhibitory activity against bovine carbonic anhydrase IV (bCAIV) | 2005 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 15, Issue:4
| Carbonic anhydrase inhibitors. Inhibition of the membrane-bound human and bovine isozymes IV with sulfonamides. |
| AID1275911 | Inhibition of Vibrio cholerae alpha-carbonic anhydrase using CO2 as substrate preincubated for 15 mins by stopped-flow CO2 hydration assay | 2016 | Bioorganic & medicinal chemistry, Mar-01, Volume: 24, Issue:5
| Sulfonamide inhibition studies of the β-carbonic anhydrase from the pathogenic bacterium Vibrio cholerae. |
| AID1453413 | Inhibition of human carbonic anhydrase-2 assessed as reduction in CO2 hydration preincubated for 15 mins followed by CO2 addition measured for 10 to 100 secs by stopped-flow assay | | | |
| AID669117 | Inhibition of Candida albicans CaNce103 preincubated for 15 mins measured for 10 to 100 sec by stopped-flow method | 2012 | Journal of medicinal chemistry, Apr-12, Volume: 55, Issue:7
| Molecular cloning, characterization, and inhibition studies of a β-carbonic anhydrase from Malassezia globosa, a potential antidandruff target. |
| AID1628037 | Inhibition of human cytosolic carbonic anhydrase 2 preincubated for 15 mins by stop flow CO2 hydrase assay | 2016 | Bioorganic & medicinal chemistry letters, 09-01, Volume: 26, Issue:17
| Cloning, expression, purification and sulfonamide inhibition profile of the complete domain of the η-carbonic anhydrase from Plasmodium falciparum. |
| AID1268964 | Inhibition of recombinant Sulfurihydrogenibium yellowstonense YO3AOP1 carbonic anhydrase by stopped flow CO2 hydrase assay | 2016 | Bioorganic & medicinal chemistry letters, Jan-15, Volume: 26, Issue:2
| Sulfonamide inhibition studies of the α-carbonic anhydrase from the gammaproteobacterium Thiomicrospira crunogena XCL-2, TcruCA. |
| AID612725 | Inhibition of human recombinant carbonic anhydrase 1 at pH 7.5 by stopped flow CO2 hydration assay | 2011 | Bioorganic & medicinal chemistry, Aug-15, Volume: 19, Issue:16
| Inhibition studies of the β-carbonic anhydrases from the bacterial pathogen Salmonella enterica serovar Typhimurium with sulfonamides and sulfamates. |
| AID350900 | Inhibition of CO2-hydratase activity of human carbonic anhydrase 2 by CO2 hydration method | 2009 | Bioorganic & medicinal chemistry, May-01, Volume: 17, Issue:9
| Effects of new 5-amino-1,3,4-thiadiazole-2-sulfonamide derivatives on human carbonic anhydrase isozymes. |
| AID644381 | Inhibition of human recombinant carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration assay | 2012 | Bioorganic & medicinal chemistry, Feb-15, Volume: 20, Issue:4
| Cloning, characterization and sulfonamide inhibition studies of an α-carbonic anhydrase from the living fossil sponge Astrosclera willeyana. |
| AID1190063 | Inhibition of human recombinant carbonic anhydrase 1 by stopped-flow CO2 hydration assay | 2015 | Bioorganic & medicinal chemistry, Feb-01, Volume: 23, Issue:3
| Sulfonamide inhibition studies of the η-class carbonic anhydrase from the malaria pathogen Plasmodium falciparum. |
| AID1434428 | Inhibition of human carbonic anhydrase 2 assessed as reduction in CO2 hydration preincubated for 15 mins followed by CO2 addition measured for 10 to 100 sec by Line-Weaver Burk plot analysis | | | |
| AID1268962 | Inhibition of recombinant human carbonic anhydrase-1 by stopped flow CO2 hydrase assay | 2016 | Bioorganic & medicinal chemistry letters, Jan-15, Volume: 26, Issue:2
| Sulfonamide inhibition studies of the α-carbonic anhydrase from the gammaproteobacterium Thiomicrospira crunogena XCL-2, TcruCA. |
| AID1188135 | Inhibition of human recombinant Carbonic anhydrase 2 compound preincubated for 15 mins by stopped flow CO2 hydrase assay method | 2014 | Bioorganic & medicinal chemistry, Sep-01, Volume: 22, Issue:17
| Sulfonamide inhibition study of the carbonic anhydrases from the bacterial pathogen Porphyromonas gingivalis: the β-class (PgiCAb) versus the γ-class (PgiCA) enzymes. |
| AID493886 | Inhibition of human recombinant carbonic anhydrase 4 after 15 mins by stopped-flow CO2 hydration assay | 2010 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 20, Issue:15
| Carbonic anhydrase inhibitors. The X-ray crystal structure of human isoform II in adduct with an adamantyl analogue of acetazolamide resides in a less utilized binding pocket than most hydrophobic inhibitors. |
| AID1434427 | Inhibition of recombinant human carbonic anhydrase 1 assessed as reduction in CO2 hydration preincubated for 15 mins followed by CO2 addition measured for 10 to 100 sec by Line-Weaver Burk plot analysis | | | |
| AID493883 | Inhibition of human recombinant carbonic anhydrase 1 after 15 mins by stopped-flow CO2 hydration assay | 2010 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 20, Issue:15
| Carbonic anhydrase inhibitors. The X-ray crystal structure of human isoform II in adduct with an adamantyl analogue of acetazolamide resides in a less utilized binding pocket than most hydrophobic inhibitors. |
| AID612731 | Inhibition of Salmonella Typhimurium recombinant carbonic anhydrase 1 at pH 8.3 by stopped flow CO2 hydration assay | 2011 | Bioorganic & medicinal chemistry, Aug-15, Volume: 19, Issue:16
| Inhibition studies of the β-carbonic anhydrases from the bacterial pathogen Salmonella enterica serovar Typhimurium with sulfonamides and sulfamates. |
| AID243011 | Selectivity ratio against human carbonic anhydrases II and XII | 2005 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 15, Issue:4
| Carbonic anhydrase inhibitors. Inhibition of the transmembrane isozyme XII with sulfonamides-a new target for the design of antitumor and antiglaucoma drugs? |
| AID48279 | Inhibitory activity against bovine carbonic anhydrase IV (CA4), isolated from bovine lung microsomes | 2000 | Journal of medicinal chemistry, Jan-27, Volume: 43, Issue:2
| Carbonic anhydrase inhibitors: synthesis of membrane-impermeant low molecular weight sulfonamides possessing in vivo selectivity for the membrane-bound versus cytosolic isozymes. |
| AID1240216 | Inhibition of Methanosarcina thermophila recombinant gamma carbonic anhydrase by stopped flow CO2 hydrase assay method | 2015 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 25, Issue:17
| Sulfonamide inhibition studies of the γ-carbonic anhydrase from the Antarctic bacterium Pseudoalteromonas haloplanktis. |
| AID1275913 | Inhibition of human Carbonic anhydrase1 using CO2 as substrate preincubated for 15 mins by stopped-flow CO2 hydration assay | 2016 | Bioorganic & medicinal chemistry, Mar-01, Volume: 24, Issue:5
| Sulfonamide inhibition studies of the β-carbonic anhydrase from the pathogenic bacterium Vibrio cholerae. |
| AID1278411 | Inhibition of Nostoc commune gamma carbonic anhydrase preincubated for 15 mins by stopped flow CO2 hydration assay | 2016 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 26, Issue:4
| Sulfonamide inhibition studies of the γ-carbonic anhydrase from the Antarctic bacterium Colwellia psychrerythraea. |
| AID1287520 | Inhibition of recombinant Enterobacter sp. B13 beta carbonic anhydrase incubated for 15 mins by stopped-flow CO2 hydration assay | 2016 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 26, Issue:7
| Sulfonamide inhibition studies of the β-carbonic anhydrase from the newly discovered bacterium Enterobacter sp. B13. |
| AID239102 | Inhibitory constant against catalytic domain of human carbonic anhydrase IX | 2005 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 15, Issue:17
| Carbonic anhydrase inhibitors: inhibition of the transmembrane isozyme XIV with sulfonamides. |
| AID275806 | Inhibition of full length human recombinant CA VI | 2007 | Journal of medicinal chemistry, Jan-25, Volume: 50, Issue:2
| Carbonic anhydrase inhibitors. DNA cloning, characterization, and inhibition studies of the human secretory isoform VI, a new target for sulfonamide and sulfamate inhibitors. |
| AID320311 | Inhibition of human recombinant full length carbonic hydrase 6 by stopped-flow CO2 hydration assay | 2008 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 18, Issue:3
| Carbonic anhydrase inhibitors. Interaction of 2-N,N-dimethylamino-1,3,4-thiadiazole-5-methanesulfonamide with 12 mammalian isoforms: kinetic and X-ray crystallographic studies. |
| AID222125 | Inhibition of cloned isozyme, human carbonic anhydrase I | 2001 | Bioorganic & medicinal chemistry letters, Feb-26, Volume: 11, Issue:4
| Carbonic anhydrase inhibitors: synthesis of sulfonamides incorporating dtpa tails and of their zinc complexes with powerful topical antiglaucoma properties. |
| AID350902 | Inhibition of esterase activity of human carbonic anhydrase 2 by CO2 hydration method | 2009 | Bioorganic & medicinal chemistry, May-01, Volume: 17, Issue:9
| Effects of new 5-amino-1,3,4-thiadiazole-2-sulfonamide derivatives on human carbonic anhydrase isozymes. |
| AID349608 | Inhibition of full length Mycobacterium tuberculosis H37Rv recombinant carbonic anhydrase 3 expressed in Escherichia coli BL21 by stopped flow CO2 hydration assay | 2009 | Journal of medicinal chemistry, May-14, Volume: 52, Issue:9
| Carbonic anhydrase inhibitors. Cloning, characterization, and inhibition studies of a new beta-carbonic anhydrase from Mycobacterium tuberculosis. |
| AID275807 | Inhibition of human recombinant cytosolic isozyme CA I by stopped-flow CO2 hydrase method | 2007 | Journal of medicinal chemistry, Jan-25, Volume: 50, Issue:2
| Carbonic anhydrase inhibitors. DNA cloning, characterization, and inhibition studies of the human secretory isoform VI, a new target for sulfonamide and sulfamate inhibitors. |
| AID1287519 | Inhibition of Vibrio cholerae beta carbonic anhydrase incubated for 15 mins by stopped-flow CO2 hydration assay | 2016 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 26, Issue:7
| Sulfonamide inhibition studies of the β-carbonic anhydrase from the newly discovered bacterium Enterobacter sp. B13. |
| AID648181 | Inhibition of human wild type carbonic anhydrase 2 Leu204Ser mutant expressed in Escherichia coli after 15 mins preincubation by stopped flow CO2 hydration assay | 2012 | Bioorganic & medicinal chemistry, Apr-01, Volume: 20, Issue:7
| Mutation of active site residues Asn67 to Ile, Gln92 to Val and Leu204 to Ser in human carbonic anhydrase II: influences on the catalytic activity and affinity for inhibitors. |
| AID369271 | Inhibition of human recombinant carbonic anhydrase 1 by stopped flow CO2 hydrase assay | 2009 | Journal of medicinal chemistry, Feb-12, Volume: 52, Issue:3
| Cloning, expression, post-translational modifications and inhibition studies on the latest mammalian carbonic anhydrase isoform, CA XV. |
| AID263050 | Inhibition of bovine CA4 | 2006 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 16, Issue:7
| QSAR study on topically acting sulfonamides incorporating GABA moieties: a molecular connectivity approach. |
| AID1142836 | Inhibition of Legionella pneumophilia subsp. Pneumophila strain Philadelphia-1 carbonic anhydrase-1 assessed as CO2 hydrase activity by stopped-flow assay | 2014 | Bioorganic & medicinal chemistry, Jun-01, Volume: 22, Issue:11
| Sulfonamide inhibition studies of two β-carbonic anhydrases from the bacterial pathogen Legionella pneumophila. |
| AID47932 | Inhibitory activity against human carbonic anhydrase II (CA2) | 2000 | Journal of medicinal chemistry, Jan-27, Volume: 43, Issue:2
| Carbonic anhydrase inhibitors: synthesis of membrane-impermeant low molecular weight sulfonamides possessing in vivo selectivity for the membrane-bound versus cytosolic isozymes. |
| AID552128 | Inhibition of human recombinant CA2 by stopped-flow CO2 hydration assay | 2011 | Bioorganic & medicinal chemistry letters, Jan-15, Volume: 21, Issue:2
| Carbonic anhydrase inhibitors. Inhibition studies with anions and sulfonamides of a new cytosolic enzyme from the scleractinian coral Stylophora pistillata. |
| AID1291355 | Inhibition of recombinant Vibrio cholerae beta-carbonic anhydrase preincubated for 15 mins by stopped-flow CO2 hydration assay | 2016 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 26, Issue:8
| Comparison of the sulfonamide inhibition profiles of the α-, β- and γ-carbonic anhydrases from the pathogenic bacterium Vibrio cholerae. |
| AID299242 | Inhibition of human carbonic anhydrase 1 by stopped-flow CO2 hydrase assay | 2007 | Bioorganic & medicinal chemistry letters, Jul-01, Volume: 17, Issue:13
| Carbonic anhydrase inhibitors: the beta-carbonic anhydrase from Helicobacter pylori is a new target for sulfonamide and sulfamate inhibitors. |
| AID612726 | Inhibition of human recombinant carbonic anhydrase 2 at pH 7.5 by stopped flow CO2 hydration assay | 2011 | Bioorganic & medicinal chemistry, Aug-15, Volume: 19, Issue:16
| Inhibition studies of the β-carbonic anhydrases from the bacterial pathogen Salmonella enterica serovar Typhimurium with sulfonamides and sulfamates. |
| AID367820 | Inhibition of human recombinant CA1 by stopped-flow CO2 hydrase assay | 2009 | Bioorganic & medicinal chemistry, Feb-01, Volume: 17, Issue:3
| Carbonic anhydrase inhibitors: inhibition of the beta-class enzyme from the yeast Saccharomyces cerevisiae with sulfonamides and sulfamates. |
| AID725955 | Inhibition of human recombinant carbonic anhydrase 1 by stopped flow CO2 hydration assay | 2013 | Journal of medicinal chemistry, Feb-28, Volume: 56, Issue:4
| Cloning, characterization, and sulfonamide and thiol inhibition studies of an α-carbonic anhydrase from Trypanosoma cruzi, the causative agent of Chagas disease. |
| AID369274 | Inhibition of human recombinant carbonic anhydrase 9 catalytic domain by stopped flow CO2 hydrase assay | 2009 | Journal of medicinal chemistry, Feb-12, Volume: 52, Issue:3
| Cloning, expression, post-translational modifications and inhibition studies on the latest mammalian carbonic anhydrase isoform, CA XV. |
| AID261582 | Selectivity ratio for human carbonic anhydrase 2 over Helicobacter pylori carbonic anhydrase | 2006 | Journal of medicinal chemistry, Mar-23, Volume: 49, Issue:6
| Carbonic anhydrase inhibitors: DNA cloning and inhibition studies of the alpha-carbonic anhydrase from Helicobacter pylori, a new target for developing sulfonamide and sulfamate gastric drugs. |
| AID436563 | Inhibition of human recombinant CA1 by stopped-flow CO2 assay | 2009 | Bioorganic & medicinal chemistry, Jul-15, Volume: 17, Issue:14
| Carbonic anhydrase inhibitors. Inhibition studies of a coral secretory isoform by sulfonamides. |
| AID369272 | Inhibition of human recombinant carbonic anhydrase 2 by stopped flow CO2 hydrase assay | 2009 | Journal of medicinal chemistry, Feb-12, Volume: 52, Issue:3
| Cloning, expression, post-translational modifications and inhibition studies on the latest mammalian carbonic anhydrase isoform, CA XV. |
| AID349607 | Inhibition of Mycobacterium tuberculosis recombinant carbonic anhydrase 1 encoded by Rv1284 by stopped flow CO2 hydration assay | 2009 | Journal of medicinal chemistry, May-14, Volume: 52, Issue:9
| Carbonic anhydrase inhibitors. Cloning, characterization, and inhibition studies of a new beta-carbonic anhydrase from Mycobacterium tuberculosis. |
| AID1195371 | Inhibition of Anopheles gambiae carbonic anhydrase pre-incubated for 15 mins by stopped-flow CO2 hydration assay | 2015 | Bioorganic & medicinal chemistry, May-15, Volume: 23, Issue:10
| The β-carbonic anhydrase from the malaria mosquito Anopheles gambiae is highly inhibited by sulfonamides. |
| AID275808 | Inhibition of human recombinant cytosolic isozyme CA II by stopped-flow CO2 hydrase method | 2007 | Journal of medicinal chemistry, Jan-25, Volume: 50, Issue:2
| Carbonic anhydrase inhibitors. DNA cloning, characterization, and inhibition studies of the human secretory isoform VI, a new target for sulfonamide and sulfamate inhibitors. |
| AID493885 | Inhibition of human recombinant carbonic anhydrase 3 after 15 mins by stopped-flow CO2 hydration assay | 2010 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 20, Issue:15
| Carbonic anhydrase inhibitors. The X-ray crystal structure of human isoform II in adduct with an adamantyl analogue of acetazolamide resides in a less utilized binding pocket than most hydrophobic inhibitors. |
| AID725956 | Inhibition of human recombinant carbonic anhydrase 2 by stopped flow CO2 hydration assay | 2013 | Journal of medicinal chemistry, Feb-28, Volume: 56, Issue:4
| Cloning, characterization, and sulfonamide and thiol inhibition studies of an α-carbonic anhydrase from Trypanosoma cruzi, the causative agent of Chagas disease. |
| AID1434429 | Inhibition of Burkholderia pseudomallei Gamma-carbonic anhydrase assessed as reduction in CO2 hydration preincubated for 15 mins followed by CO2 addition measured for 10 to 100 sec by Line-Weaver Burk plot analysis | | | |
| AID1287517 | Inhibition of human carbonic anhydrase 1 incubated for 15 mins by stopped-flow CO2 hydration assay | 2016 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 26, Issue:7
| Sulfonamide inhibition studies of the β-carbonic anhydrase from the newly discovered bacterium Enterobacter sp. B13. |
| AID238256 | Ki value against human carbonic anhydrase VII | 2005 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 15, Issue:4
| Carbonic anhydrase inhibitors. Inhibition of the human cytosolic isozyme VII with aromatic and heterocyclic sulfonamides. |
| AID648179 | Inhibition of human wild type carbonic anhydrase 2 Asn67Ile mutant expressed in Escherichia coli after 15 mins preincubation by stopped flow CO2 hydration assay | 2012 | Bioorganic & medicinal chemistry, Apr-01, Volume: 20, Issue:7
| Mutation of active site residues Asn67 to Ile, Gln92 to Val and Leu204 to Ser in human carbonic anhydrase II: influences on the catalytic activity and affinity for inhibitors. |
| AID493889 | Inhibition of human recombinant carbonic anhydrase 6 after 15 mins by stopped-flow CO2 hydration assay | 2010 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 20, Issue:15
| Carbonic anhydrase inhibitors. The X-ray crystal structure of human isoform II in adduct with an adamantyl analogue of acetazolamide resides in a less utilized binding pocket than most hydrophobic inhibitors. |
| AID537658 | Inhibition of human carbonic anhydrase 1 esterase activity by spectrophotometry | 2010 | European journal of medicinal chemistry, Nov, Volume: 45, Issue:11
| Synthesis, characterization and antiglaucoma activity of some novel pyrazole derivatives of 5-amino-1,3,4-thiadiazole-2-sulfonamide. |
| AID47939 | Inhibitory activity against human recombinant carbonic anhydrase II (CA2) | 1999 | Journal of medicinal chemistry, Sep-09, Volume: 42, Issue:18
| Carbonic anhydrase inhibitors: synthesis of water-soluble, aminoacyl/dipeptidyl sulfonamides possessing long-lasting intraocular pressure-lowering properties via the topical route. |
| AID1726079 | Inhibition of Vibrio cholerae beta carbonic anhydrase pre-incubated for 15 mins prior to testing by phenol red-based stopped-flow CO2 hydration assay | 2020 | ACS medicinal chemistry letters, Nov-12, Volume: 11, Issue:11
| In Silico-Guided Identification of New Potent Inhibitors of Carbonic Anhydrases Expressed in |
| AID47936 | Inhibition of human carbonic anhydrase II | 2003 | Bioorganic & medicinal chemistry letters, Mar-24, Volume: 13, Issue:6
| Carbonic anhydrase inhibitors: inhibition of the tumor-associated isozyme IX with aromatic and heterocyclic sulfonamides. |
| AID577526 | Inhibition of human carbonic anhydrase I by spectrophotometry at pH 7.5 | 2011 | Bioorganic & medicinal chemistry, Feb-01, Volume: 19, Issue:3
| A new β-carbonic anhydrase from Brucella suis, its cloning, characterization, and inhibition with sulfonamides and sulfamates, leading to impaired pathogen growth. |
| AID48296 | Inhibitory activity against human tumor-associated transmembrane carbonic anhydrase IX. | 2004 | Bioorganic & medicinal chemistry letters, Jun-21, Volume: 14, Issue:12
| Carbonic anhydrase inhibitors: the first QSAR study on inhibition of tumor-associated isoenzyme IX with aromatic and heterocyclic sulfonamides. |
| AID301521 | Inhibition of human cloned carbonic anhydrase1 by CO2 hydration method | 2007 | Bioorganic & medicinal chemistry, Nov-15, Volume: 15, Issue:22
| Design, synthesis, and docking studies of new 1,3,4-thiadiazole-2-thione derivatives with carbonic anhydrase inhibitory activity. |
| AID47931 | Inhibition constant (Ki) against human cloned carbonic anhydrase II (CAH) | 2003 | Journal of medicinal chemistry, May-22, Volume: 46, Issue:11
| Carbonic anhydrase inhibitors. Inhibition of tumor-associated isozyme IX by halogenosulfanilamide and halogenophenylaminobenzolamide derivatives. |
| AID350899 | Inhibition of CO2-hydratase activity of human carbonic anhydrase 1 by CO2 hydration method | 2009 | Bioorganic & medicinal chemistry, May-01, Volume: 17, Issue:9
| Effects of new 5-amino-1,3,4-thiadiazole-2-sulfonamide derivatives on human carbonic anhydrase isozymes. |
| AID1453412 | Inhibition of human carbonic anhydrase-1 assessed as reduction in CO2 hydration preincubated for 15 mins followed by CO2 addition measured for 10 to 100 secs by stopped-flow assay | | | |
| AID238536 | Inhibitory activity against human carbonic anhydrase I (hCAI) | 2005 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 15, Issue:4
| Carbonic anhydrase inhibitors. Inhibition of the membrane-bound human and bovine isozymes IV with sulfonamides. |
| AID263639 | Selectivity for Helicobacter pylori recombinant CA over human recombinant CA2 | 2006 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 16, Issue:8
| Carbonic anhydrase inhibitors: cloning and sulfonamide inhibition studies of a carboxyterminal truncated alpha-carbonic anhydrase from Helicobacter pylori. |
| AID48289 | Inhibition of bovine carbonic anhydrase IV from bovine lung microsomes | 2000 | Bioorganic & medicinal chemistry letters, May-15, Volume: 10, Issue:10
| Carbonic anhydrase inhibitors: synthesis of N-morpholylthiocarbonylsulfenylamino aromatic/heterocyclic sulfonamides and their interaction with isozymes I, II and IV. |
| AID577527 | Inhibition of human carbonic anhydrase II by spectrophotometry at pH 7.5 | 2011 | Bioorganic & medicinal chemistry, Feb-01, Volume: 19, Issue:3
| A new β-carbonic anhydrase from Brucella suis, its cloning, characterization, and inhibition with sulfonamides and sulfamates, leading to impaired pathogen growth. |
| AID493890 | Inhibition of human recombinant carbonic anhydrase 7 after 15 mins by stopped-flow CO2 hydration assay | 2010 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 20, Issue:15
| Carbonic anhydrase inhibitors. The X-ray crystal structure of human isoform II in adduct with an adamantyl analogue of acetazolamide resides in a less utilized binding pocket than most hydrophobic inhibitors. |
| AID459696 | Inhibition of Brucella suis CA1 expressed in Escherichia coli BL21(DE3) by stopped-flow CO2-hydration assay | 2010 | Journal of medicinal chemistry, Mar-11, Volume: 53, Issue:5
| Cloning, characterization, and inhibition studies of a beta-carbonic anhydrase from Brucella suis. |
| AID552127 | Inhibition of human recombinant CA1 by stopped-flow CO2 hydration assay | 2011 | Bioorganic & medicinal chemistry letters, Jan-15, Volume: 21, Issue:2
| Carbonic anhydrase inhibitors. Inhibition studies with anions and sulfonamides of a new cytosolic enzyme from the scleractinian coral Stylophora pistillata. |
| AID1142837 | Inhibition of Legionella pneumophilia subsp. Pneumophila strain Philadelphia-1 carbonic anhydrase-2 assessed as CO2 hydrase activity by stopped-flow assay | 2014 | Bioorganic & medicinal chemistry, Jun-01, Volume: 22, Issue:11
| Sulfonamide inhibition studies of two β-carbonic anhydrases from the bacterial pathogen Legionella pneumophila. |
| AID239223 | Inhibitory potency against human cloned Carbonic anhydrase I expressed in Escherichia coli strain BL21 | 2005 | Bioorganic & medicinal chemistry letters, Jan-17, Volume: 15, Issue:2
| Carbonic anhydrase inhibitors. Novel sulfanilamide/acetazolamide derivatives obtained by the tail approach and their interaction with the cytosolic isozymes I and II, and the tumor-associated isozyme IX. |
| AID493884 | Inhibition of human recombinant carbonic anhydrase 2 after 15 mins by stopped-flow CO2 hydration assay | 2010 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 20, Issue:15
| Carbonic anhydrase inhibitors. The X-ray crystal structure of human isoform II in adduct with an adamantyl analogue of acetazolamide resides in a less utilized binding pocket than most hydrophobic inhibitors. |
| AID1190065 | Inhibition of Plasmodium falciparum Eta-carbonic anhydrase pre-incubated for 15 mins before CO2 substrate addition by stopped-flow CO2 hydration assay | 2015 | Bioorganic & medicinal chemistry, Feb-01, Volume: 23, Issue:3
| Sulfonamide inhibition studies of the η-class carbonic anhydrase from the malaria pathogen Plasmodium falciparum. |
| AID369273 | Inhibition of human full length recombinant carbonic anhydrase 6 by stopped flow CO2 hydrase assay | 2009 | Journal of medicinal chemistry, Feb-12, Volume: 52, Issue:3
| Cloning, expression, post-translational modifications and inhibition studies on the latest mammalian carbonic anhydrase isoform, CA XV. |
| AID537653 | Inhibition of human carbonic anhydrase 2 esterase activity by spectrophotometry | 2010 | European journal of medicinal chemistry, Nov, Volume: 45, Issue:11
| Synthesis, characterization and antiglaucoma activity of some novel pyrazole derivatives of 5-amino-1,3,4-thiadiazole-2-sulfonamide. |
| AID50374 | Inhibitory activity against human recombinant carbonic anhydrase I (CA1) | 1999 | Journal of medicinal chemistry, Sep-09, Volume: 42, Issue:18
| Carbonic anhydrase inhibitors: synthesis of water-soluble, aminoacyl/dipeptidyl sulfonamides possessing long-lasting intraocular pressure-lowering properties via the topical route. |
| AID1291363 | Inhibition of recombinant Vibrio cholerae gamma-carbonic anhydrase preincubated for 15 mins by stopped-flow CO2 hydration assay | 2016 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 26, Issue:8
| Comparison of the sulfonamide inhibition profiles of the α-, β- and γ-carbonic anhydrases from the pathogenic bacterium Vibrio cholerae. |
| AID612732 | Inhibition of Salmonella Typhimurium recombinant carbonic anhydrase 2 at pH 8.3 by stopped flow CO2 hydration assay | 2011 | Bioorganic & medicinal chemistry, Aug-15, Volume: 19, Issue:16
| Inhibition studies of the β-carbonic anhydrases from the bacterial pathogen Salmonella enterica serovar Typhimurium with sulfonamides and sulfamates. |
| AID238276 | Ki value against human carbonic anhydrase I (hCA I) | 2005 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 15, Issue:4
| Carbonic anhydrase inhibitors. Inhibition of the transmembrane isozyme XII with sulfonamides-a new target for the design of antitumor and antiglaucoma drugs? |
| AID493895 | Inhibition of mouse recombinant carbonic anhydrase 15 after 15 mins by stopped-flow CO2 hydration assay | 2010 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 20, Issue:15
| Carbonic anhydrase inhibitors. The X-ray crystal structure of human isoform II in adduct with an adamantyl analogue of acetazolamide resides in a less utilized binding pocket than most hydrophobic inhibitors. |
| AID1194024 | Inhibition of human recombinant carbonic anhydrase 1 by stopped flow CO2 hydrase assay | 2015 | Bioorganic & medicinal chemistry, Apr-15, Volume: 23, Issue:8
| Sulfonamide inhibition studies of the γ-carbonic anhydrase from the Antarctic cyanobacterium Nostoc commune. |
| AID744415 | Inhibition of recombinant full length Candida glabrata NCE103 expressed in Escherichia coli BL21 preincubated for 15 mins by stopped-flow CO2 hydrase assay | 2013 | Bioorganic & medicinal chemistry letters, May-01, Volume: 23, Issue:9
| Carbonic anhydrase inhibitors: inhibition of the β-class enzyme from the pathogenic yeast Candida glabrata with sulfonamides, sulfamates and sulfamides. |
| AID1291361 | Inhibition of recombinant Vibrio cholerae alpha-carbonic anhydrase preincubated for 15 mins by stopped-flow CO2 hydration assay | 2016 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 26, Issue:8
| Comparison of the sulfonamide inhibition profiles of the α-, β- and γ-carbonic anhydrases from the pathogenic bacterium Vibrio cholerae. |
| AID238316 | Ki value against human carbonic anhydrase XII (hCA XII) | 2005 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 15, Issue:4
| Carbonic anhydrase inhibitors. Inhibition of the transmembrane isozyme XII with sulfonamides-a new target for the design of antitumor and antiglaucoma drugs? |
| AID1194028 | Inhibition of recombinant Nostoc commune gamma-carbonic anhydrase preincubated for 15 mins by stopped flow CO2 hydrase assay | 2015 | Bioorganic & medicinal chemistry, Apr-15, Volume: 23, Issue:8
| Sulfonamide inhibition studies of the γ-carbonic anhydrase from the Antarctic cyanobacterium Nostoc commune. |
| AID1061069 | Inhibition of human recombinant carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration assay | 2014 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 24, Issue:1
| Sulfonamide inhibition studies of the δ-carbonic anhydrase from the diatom Thalassiosira weissflogii. |
| AID1278413 | Inhibition of recombinant Colwellia psychrerythraea gamma carbonic anhydrase preincubated for 15 mins by stopped flow CO2 hydration assay | 2016 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 26, Issue:4
| Sulfonamide inhibition studies of the γ-carbonic anhydrase from the Antarctic bacterium Colwellia psychrerythraea. |
| AID238225 | Inhibitory constant against human Carbonic anhydrase IX | 2005 | Bioorganic & medicinal chemistry letters, May-02, Volume: 15, Issue:9
| Carbonic anhydrase inhibitors. Inhibition of the cytosolic and tumor-associated carbonic anhydrase isozymes I, II, and IX with a series of 1,3,4-thiadiazole- and 1,2,4-triazole-thiols. |
| AID1188137 | Inhibition of Porphyromonas gingivalis Beta-carbonic anhydrase compound preincubated for 15 mins by stopped flow CO2 hydrase assay method | 2014 | Bioorganic & medicinal chemistry, Sep-01, Volume: 22, Issue:17
| Sulfonamide inhibition study of the carbonic anhydrases from the bacterial pathogen Porphyromonas gingivalis: the β-class (PgiCAb) versus the γ-class (PgiCA) enzymes. |
| AID261580 | Inhibition of human recombinant carbonic anhydrase 2 by stopped-flow CO2 hydrase assay | 2006 | Journal of medicinal chemistry, Mar-23, Volume: 49, Issue:6
| Carbonic anhydrase inhibitors: DNA cloning and inhibition studies of the alpha-carbonic anhydrase from Helicobacter pylori, a new target for developing sulfonamide and sulfamate gastric drugs. |
| AID552130 | Inhibition of Stylophora pistillata carbonic anhydrase by stopped-flow CO2 hydration assay | 2011 | Bioorganic & medicinal chemistry letters, Jan-15, Volume: 21, Issue:2
| Carbonic anhydrase inhibitors. Inhibition studies with anions and sulfonamides of a new cytosolic enzyme from the scleractinian coral Stylophora pistillata. |
| AID414955 | Inhibition of human recombinant carbonic anhydrase 1 by stopped flow CO2 hydration method | 2009 | Journal of medicinal chemistry, Apr-23, Volume: 52, Issue:8
| Molecular cloning, characterization, and inhibition studies of the Rv1284 beta-carbonic anhydrase from Mycobacterium tuberculosis with sulfonamides and a sulfamate. |
| AID320310 | Inhibition of human recombinant full length carbonic hydrase 5B by stopped-flow CO2 hydration assay | 2008 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 18, Issue:3
| Carbonic anhydrase inhibitors. Interaction of 2-N,N-dimethylamino-1,3,4-thiadiazole-5-methanesulfonamide with 12 mammalian isoforms: kinetic and X-ray crystallographic studies. |
| AID367822 | Inhibition of Saccharomyces cerevisiae recombinant CA expressed in Escherichia coli by stopped-flow CO2 hydrase assay | 2009 | Bioorganic & medicinal chemistry, Feb-01, Volume: 17, Issue:3
| Carbonic anhydrase inhibitors: inhibition of the beta-class enzyme from the yeast Saccharomyces cerevisiae with sulfonamides and sulfamates. |
| AID50371 | Inhibitory activity against human cloned carbonic anhydrase isozyme I by esterase assay method. | 2003 | Bioorganic & medicinal chemistry letters, Mar-24, Volume: 13, Issue:6
| Carbonic anhydrase inhibitors: inhibition of the tumor-associated isozyme IX with aromatic and heterocyclic sulfonamides. |
| AID1628038 | Inhibition of recombinant Plasmodium falciparum eta-carbonic anhydrase (181 to 538 residues) expressed in Escherichia coli artic express (DE3) preincubated for 15 mins by stop flow CO2 hydrase assay | 2016 | Bioorganic & medicinal chemistry letters, 09-01, Volume: 26, Issue:17
| Cloning, expression, purification and sulfonamide inhibition profile of the complete domain of the η-carbonic anhydrase from Plasmodium falciparum. |
| AID238209 | Inhibitory constant against human Carbonic anhydrase I | 2005 | Bioorganic & medicinal chemistry letters, May-02, Volume: 15, Issue:9
| Carbonic anhydrase inhibitors. Inhibition of the cytosolic and tumor-associated carbonic anhydrase isozymes I, II, and IX with a series of 1,3,4-thiadiazole- and 1,2,4-triazole-thiols. |
| AID50370 | Inhibitory activity against human cloned carbonic anhydrase isozyme I (hCA I, cytosolic form). | 1999 | Journal of medicinal chemistry, Jul-15, Volume: 42, Issue:14
| Carbonic anhydrase inhibitors. Synthesis of water-soluble, topically effective, intraocular pressure-lowering aromatic/heterocyclic sulfonamides containing cationic or anionic moieties: is the tail more important than the ring? |
| AID539004 | Inhibition of Aspergillus fumigatus ChiA1 expressed in Pichia pastoris at 1 mM after 70 mins | 2010 | Bioorganic & medicinal chemistry, Dec-01, Volume: 18, Issue:23
| Acetazolamide-based fungal chitinase inhibitors. |
| AID238567 | Ki value against murine carbonic anhydrase XIII was determined; (not tested) | 2005 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 15, Issue:4
| Carbonic anhydrase inhibitors. Inhibition of the human cytosolic isozyme VII with aromatic and heterocyclic sulfonamides. |
| AID349605 | Inhibition of human recombinant carbonic anhydrase 1 by stopped flow CO2 hydration assay | 2009 | Journal of medicinal chemistry, May-14, Volume: 52, Issue:9
| Carbonic anhydrase inhibitors. Cloning, characterization, and inhibition studies of a new beta-carbonic anhydrase from Mycobacterium tuberculosis. |
| AID263049 | Inhibition of human CA2 | 2006 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 16, Issue:7
| QSAR study on topically acting sulfonamides incorporating GABA moieties: a molecular connectivity approach. |
| AID320307 | Inhibition of human recombinant full length carbonic hydrase 3 by stopped-flow CO2 hydration assay | 2008 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 18, Issue:3
| Carbonic anhydrase inhibitors. Interaction of 2-N,N-dimethylamino-1,3,4-thiadiazole-5-methanesulfonamide with 12 mammalian isoforms: kinetic and X-ray crystallographic studies. |
| AID1188134 | Inhibition of human recombinant Carbonic anhydrase 1 compound preincubated for 15 mins by stopped flow CO2 hydrase assay method | 2014 | Bioorganic & medicinal chemistry, Sep-01, Volume: 22, Issue:17
| Sulfonamide inhibition study of the carbonic anhydrases from the bacterial pathogen Porphyromonas gingivalis: the β-class (PgiCAb) versus the γ-class (PgiCA) enzymes. |
| AID48280 | Inhibitory activity against bovine carbonic anhydrase isozyme IV isolated from bovine lung microsomes, by esterase assay method. | 2003 | Bioorganic & medicinal chemistry letters, Mar-24, Volume: 13, Issue:6
| Carbonic anhydrase inhibitors: inhibition of the tumor-associated isozyme IX with aromatic and heterocyclic sulfonamides. |
| AID1061170 | Inhibition of Porphyromonas gingivalis gamma-carbonic anhydrase expressed in Escherichia coli preincubated for 15 mins by stopped flow CO2 hydration assay | 2014 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 24, Issue:1
| Sulfonamide inhibition studies of the γ-carbonic anhydrase from the oral pathogen Porphyromonas gingivalis. |
| AID50353 | Inhibitory activity against Human carbonic anhydrase I | 2002 | Journal of medicinal chemistry, Mar-28, Volume: 45, Issue:7
| Carbonic anhydrase inhibitors. A general approach for the preparation of water-soluble sulfonamides incorporating polyamino-polycarboxylate tails and of their metal complexes possessing long-lasting, topical intraocular pressure-lowering properties. |
| AID222126 | Inhibition of cloned isozyme, human carbonic anhydrase II | 2001 | Bioorganic & medicinal chemistry letters, Feb-26, Volume: 11, Issue:4
| Carbonic anhydrase inhibitors: synthesis of sulfonamides incorporating dtpa tails and of their zinc complexes with powerful topical antiglaucoma properties. |
| AID1190064 | Inhibition of human recombinant carbonic anhydrase 2 by stopped-flow CO2 hydration assay | 2015 | Bioorganic & medicinal chemistry, Feb-01, Volume: 23, Issue:3
| Sulfonamide inhibition studies of the η-class carbonic anhydrase from the malaria pathogen Plasmodium falciparum. |
| AID1061169 | Inhibition of recombinant Methanosarcina thermophila gamma-CA CAM by stopped flow CO2 hydration assay | 2014 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 24, Issue:1
| Sulfonamide inhibition studies of the γ-carbonic anhydrase from the oral pathogen Porphyromonas gingivalis. |
| AID263636 | Inhibition of human recombinant CA1 | 2006 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 16, Issue:8
| Carbonic anhydrase inhibitors: cloning and sulfonamide inhibition studies of a carboxyterminal truncated alpha-carbonic anhydrase from Helicobacter pylori. |
| AID238247 | Ki value against human carbonic anhydrase I | 2005 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 15, Issue:4
| Carbonic anhydrase inhibitors. Inhibition of the human cytosolic isozyme VII with aromatic and heterocyclic sulfonamides. |
| AID669115 | Inhibition of human carbonic anhydrase 2 preincubated for 15 mins measured for 10 to 100 sec by stopped-flow method | 2012 | Journal of medicinal chemistry, Apr-12, Volume: 55, Issue:7
| Molecular cloning, characterization, and inhibition studies of a β-carbonic anhydrase from Malassezia globosa, a potential antidandruff target. |
| AID47713 | Inhibition of human carbonic anhydrase I (CAI) | 2000 | Bioorganic & medicinal chemistry letters, May-15, Volume: 10, Issue:10
| Carbonic anhydrase inhibitors: synthesis of N-morpholylthiocarbonylsulfenylamino aromatic/heterocyclic sulfonamides and their interaction with isozymes I, II and IV. |
| AID263048 | Inhibition of human CA1 | 2006 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 16, Issue:7
| QSAR study on topically acting sulfonamides incorporating GABA moieties: a molecular connectivity approach. |
| AID48096 | Inhibition of human carbonic anhydrase II (hCA II) | 2000 | Bioorganic & medicinal chemistry letters, May-15, Volume: 10, Issue:10
| Carbonic anhydrase inhibitors: synthesis of N-morpholylthiocarbonylsulfenylamino aromatic/heterocyclic sulfonamides and their interaction with isozymes I, II and IV. |
| AID48284 | Inhibitory activity against bovine carbonic anhydrase IV (CA4), isolated from bovine lung microsomes | 1999 | Journal of medicinal chemistry, Sep-09, Volume: 42, Issue:18
| Carbonic anhydrase inhibitors: synthesis of water-soluble, aminoacyl/dipeptidyl sulfonamides possessing long-lasting intraocular pressure-lowering properties via the topical route. |
| AID1061066 | Inhibition of Thalassiosira weissflogii delta carbonic anhydrase preincubated for 15 mins by stopped flow CO2 hydration assay | 2014 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 24, Issue:1
| Sulfonamide inhibition studies of the δ-carbonic anhydrase from the diatom Thalassiosira weissflogii. |
| AID239422 | Inhibitory potency against catalytic domain of human Carbonic anhydrase IX expressed in Escherichia coli strain BL21 | 2005 | Bioorganic & medicinal chemistry letters, Jan-17, Volume: 15, Issue:2
| Carbonic anhydrase inhibitors. Novel sulfanilamide/acetazolamide derivatives obtained by the tail approach and their interaction with the cytosolic isozymes I and II, and the tumor-associated isozyme IX. |
| AID256964 | Inhibitory activity against human recombinant mitochondrial isozyme CA VA | 2005 | Journal of medicinal chemistry, Dec-01, Volume: 48, Issue:24
| Carbonic anhydrase inhibitors. The mitochondrial isozyme VB as a new target for sulfonamide and sulfamate inhibitors. |
| AID256965 | Inhibitory activity against human recombinant mitochondrial isozyme CA VB | 2005 | Journal of medicinal chemistry, Dec-01, Volume: 48, Issue:24
| Carbonic anhydrase inhibitors. The mitochondrial isozyme VB as a new target for sulfonamide and sulfamate inhibitors. |
| AID1278412 | Inhibition of Pseudoalteromonas haloplanktis gamma carbonic anhydrase preincubated for 15 mins by stopped flow CO2 hydration assay | 2016 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 26, Issue:4
| Sulfonamide inhibition studies of the γ-carbonic anhydrase from the Antarctic bacterium Colwellia psychrerythraea. |
| AID414956 | Inhibition of human recombinant carbonic anhydrase 2 by stopped flow CO2 hydration method | 2009 | Journal of medicinal chemistry, Apr-23, Volume: 52, Issue:8
| Molecular cloning, characterization, and inhibition studies of the Rv1284 beta-carbonic anhydrase from Mycobacterium tuberculosis with sulfonamides and a sulfamate. |
| AID1268965 | Inhibition of recombinant Thiomicrospira crunogena XCL-2 carbonic anhydrase by stopped flow CO2 hydrase assay | 2016 | Bioorganic & medicinal chemistry letters, Jan-15, Volume: 26, Issue:2
| Sulfonamide inhibition studies of the α-carbonic anhydrase from the gammaproteobacterium Thiomicrospira crunogena XCL-2, TcruCA. |
| AID497129 | Inhibition of human recombinant carbonic anhydrase 2 after 15 mins by CO2 hydration method | 2010 | Bioorganic & medicinal chemistry, Aug-01, Volume: 18, Issue:15
| Mutation of Phe91 to Asn in human carbonic anhydrase I unexpectedly enhanced both catalytic activity and affinity for sulfonamide inhibitors. |
| AID497128 | Inhibition of human recombinant carbonic anhydrase 1 Phe91Asn mutant expressed in Escherichia coli BL21 (DE3) after 15 mins by CO2 hydration method | 2010 | Bioorganic & medicinal chemistry, Aug-01, Volume: 18, Issue:15
| Mutation of Phe91 to Asn in human carbonic anhydrase I unexpectedly enhanced both catalytic activity and affinity for sulfonamide inhibitors. |
| AID726232 | Inhibition of Trypanosoma cruzi CL Brener recombinant alpha-carbonic anhydrase expressed in insect Sf9 cell Baculovirus system by stopped flow CO2 hydration assay | 2013 | Journal of medicinal chemistry, Feb-28, Volume: 56, Issue:4
| Cloning, characterization, and sulfonamide and thiol inhibition studies of an α-carbonic anhydrase from Trypanosoma cruzi, the causative agent of Chagas disease. |
| AID301523 | Inhibition of catalytic domain of human cloned carbonic anhydrase9 by CO2 hydration method | 2007 | Bioorganic & medicinal chemistry, Nov-15, Volume: 15, Issue:22
| Design, synthesis, and docking studies of new 1,3,4-thiadiazole-2-thione derivatives with carbonic anhydrase inhibitory activity. |
| AID537654 | Inhibition of human carbonic anhydrase 1 hydratase activity by spectrophotometry | 2010 | European journal of medicinal chemistry, Nov, Volume: 45, Issue:11
| Synthesis, characterization and antiglaucoma activity of some novel pyrazole derivatives of 5-amino-1,3,4-thiadiazole-2-sulfonamide. |
| AID552129 | Inhibition of human recombinant CA6 by stopped-flow CO2 hydration assay | 2011 | Bioorganic & medicinal chemistry letters, Jan-15, Volume: 21, Issue:2
| Carbonic anhydrase inhibitors. Inhibition studies with anions and sulfonamides of a new cytosolic enzyme from the scleractinian coral Stylophora pistillata. |
| AID437750 | Inhibition of full length Mycobacterium tuberculosis H37Rv recombinant carbonic anhydrase 2 encoded by RV3588c by stopped flow CO2 hydration assay | 2009 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 19, Issue:23
| Carbonic anhydrase inhibitors. Characterization and inhibition studies of the most active beta-carbonic anhydrase from Mycobacterium tuberculosis, Rv3588c. |
| AID1240217 | Inhibition of human recombinant carbonic anhydrase-2 by stopped flow CO2 hydrase assay method | 2015 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 25, Issue:17
| Sulfonamide inhibition studies of the γ-carbonic anhydrase from the Antarctic bacterium Pseudoalteromonas haloplanktis. |
| AID50366 | Inhibition constant determined against human cloned carbonic anhydrase I | 2003 | Journal of medicinal chemistry, May-22, Volume: 46, Issue:11
| Carbonic anhydrase inhibitors. Inhibition of tumor-associated isozyme IX by halogenosulfanilamide and halogenophenylaminobenzolamide derivatives. |
| AID1268963 | Inhibition of recombinant human carbonic anhydrase-2 by stopped flow CO2 hydrase assay | 2016 | Bioorganic & medicinal chemistry letters, Jan-15, Volume: 26, Issue:2
| Sulfonamide inhibition studies of the α-carbonic anhydrase from the gammaproteobacterium Thiomicrospira crunogena XCL-2, TcruCA. |
| AID256963 | Inhibitory activity against human recombinant cytosolic CA2 | 2005 | Journal of medicinal chemistry, Dec-01, Volume: 48, Issue:24
| Carbonic anhydrase inhibitors. The mitochondrial isozyme VB as a new target for sulfonamide and sulfamate inhibitors. |
| AID648180 | Inhibition of human wild type carbonic anhydrase 2 Gln92Val mutant expressed in Escherichia coli after 15 mins preincubation by stopped flow CO2 hydration assay | 2012 | Bioorganic & medicinal chemistry, Apr-01, Volume: 20, Issue:7
| Mutation of active site residues Asn67 to Ile, Gln92 to Val and Leu204 to Ser in human carbonic anhydrase II: influences on the catalytic activity and affinity for inhibitors. |
| AID320315 | Inhibition of mouse recombinant full length carbonic hydrase 13 by stopped-flow CO2 hydration assay | 2008 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 18, Issue:3
| Carbonic anhydrase inhibitors. Interaction of 2-N,N-dimethylamino-1,3,4-thiadiazole-5-methanesulfonamide with 12 mammalian isoforms: kinetic and X-ray crystallographic studies. |
| AID47935 | Inhibitory activity against human recombinant carbonic anhydrase II | 1999 | Journal of medicinal chemistry, Jul-15, Volume: 42, Issue:14
| Carbonic anhydrase inhibitors. Synthesis of water-soluble, topically effective, intraocular pressure-lowering aromatic/heterocyclic sulfonamides containing cationic or anionic moieties: is the tail more important than the ring? |
| AID711212 | Inhibition of recombinant Vibrio cholerae carbonic anhydrase expressed in Escherichia coli (DE3) preincubated for 15 mins by stopped-flow CO2 hydrase assay | 2012 | Journal of medicinal chemistry, Dec-13, Volume: 55, Issue:23
| DNA cloning, characterization, and inhibition studies of an α-carbonic anhydrase from the pathogenic bacterium Vibrio cholerae. |
| AID1278410 | Inhibition of Porphyromonas gingivalis gamma carbonic anhydrase preincubated for 15 mins by stopped flow CO2 hydration assay | 2016 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 26, Issue:4
| Sulfonamide inhibition studies of the γ-carbonic anhydrase from the Antarctic bacterium Colwellia psychrerythraea. |
| AID261579 | Inhibition of human recombinant carbonic anhydrase 1 by stopped-flow CO2 hydrase assay | 2006 | Journal of medicinal chemistry, Mar-23, Volume: 49, Issue:6
| Carbonic anhydrase inhibitors: DNA cloning and inhibition studies of the alpha-carbonic anhydrase from Helicobacter pylori, a new target for developing sulfonamide and sulfamate gastric drugs. |
| AID539002 | Inhibition of Aspergillus fumigatus ChiA1 expressed in Pichia pastoris after 70 mins | 2010 | Bioorganic & medicinal chemistry, Dec-01, Volume: 18, Issue:23
| Acetazolamide-based fungal chitinase inhibitors. |
| AID1287518 | Inhibition of human carbonic anhydrase 2 incubated for 15 mins by stopped-flow CO2 hydration assay | 2016 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 26, Issue:7
| Sulfonamide inhibition studies of the β-carbonic anhydrase from the newly discovered bacterium Enterobacter sp. B13. |
| AID436565 | Inhibition of cloned Stylophora pistillata alpha-CA expressed in human HEK293 cells by stopped-flow CO2 assay | 2009 | Bioorganic & medicinal chemistry, Jul-15, Volume: 17, Issue:14
| Carbonic anhydrase inhibitors. Inhibition studies of a coral secretory isoform by sulfonamides. |
| AID239126 | Inhibitory constant against catalytic domain of human carbonic anhydrase XII | 2005 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 15, Issue:17
| Carbonic anhydrase inhibitors: inhibition of the transmembrane isozyme XIV with sulfonamides. |
| AID470873 | Inhibition of carbonic anhydrase 2 assessed as inhibition of carbon dioxide hydration | 2009 | European journal of medicinal chemistry, Sep, Volume: 44, Issue:9
| A QSAR study on relationship between structure of sulfonamides and their carbonic anhydrase inhibitory activity using the eigenvalue (EVA) method. |
| AID301578 | Inhibition of human recombinant CA 3 assessed as CO2 hydration by stopped flow kinetic assay | 2007 | Bioorganic & medicinal chemistry, Dec-01, Volume: 15, Issue:23
| Carbonic anhydrase inhibitors: cloning, characterization, and inhibition studies of the cytosolic isozyme III with sulfonamides. |
| AID537655 | Inhibition of human carbonic anhydrase 2 hydratase activity by spectrophotometry | 2010 | European journal of medicinal chemistry, Nov, Volume: 45, Issue:11
| Synthesis, characterization and antiglaucoma activity of some novel pyrazole derivatives of 5-amino-1,3,4-thiadiazole-2-sulfonamide. |
| AID263637 | Inhibition of human recombinant CA2 | 2006 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 16, Issue:8
| Carbonic anhydrase inhibitors: cloning and sulfonamide inhibition studies of a carboxyterminal truncated alpha-carbonic anhydrase from Helicobacter pylori. |
| AID493887 | Inhibition of human recombinant carbonic anhydrase 5a after 15 mins by stopped-flow CO2 hydration assay | 2010 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 20, Issue:15
| Carbonic anhydrase inhibitors. The X-ray crystal structure of human isoform II in adduct with an adamantyl analogue of acetazolamide resides in a less utilized binding pocket than most hydrophobic inhibitors. |
| AID238255 | Ki value against human carbonic anhydrase II | 2005 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 15, Issue:4
| Carbonic anhydrase inhibitors. Inhibition of the human cytosolic isozyme VII with aromatic and heterocyclic sulfonamides. |
| AID48122 | Inhibitory activity against bovine carbonic anhydrase IV | 2002 | Journal of medicinal chemistry, Mar-28, Volume: 45, Issue:7
| Carbonic anhydrase inhibitors. A general approach for the preparation of water-soluble sulfonamides incorporating polyamino-polycarboxylate tails and of their metal complexes possessing long-lasting, topical intraocular pressure-lowering properties. |
| AID537656 | Inhibition of human carbonic anhydrase 1 by Lineweaver-Burke plot analysis | 2010 | European journal of medicinal chemistry, Nov, Volume: 45, Issue:11
| Synthesis, characterization and antiglaucoma activity of some novel pyrazole derivatives of 5-amino-1,3,4-thiadiazole-2-sulfonamide. |
| AID1204106 | Inhibition of recombinant Streptococcus mutans UA159 beta-carbonic anhydrase expressed in Escherichia coli Arctic cells preincubated for 15 mins by stopped flow CO2 hydrase assay | 2015 | Bioorganic & medicinal chemistry letters, Jun-01, Volume: 25, Issue:11
| Sulfonamide inhibition study of the β-class carbonic anhydrase from the caries producing pathogen Streptococcus mutans. |
| AID568365 | Inhibition of human carbonic anhydrase 12 preincubated for 15 mins by CO2 hydration stopped-flow assay | 2011 | Bioorganic & medicinal chemistry, Feb-15, Volume: 19, Issue:4
| Kinetic and docking studies of phenol-based inhibitors of carbonic anhydrase isoforms I, II, IX and XII evidence a new binding mode within the enzyme active site. |
| AID493893 | Inhibition of human recombinant carbonic anhydrase 13 after 15 mins by stopped-flow CO2 hydration assay | 2010 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 20, Issue:15
| Carbonic anhydrase inhibitors. The X-ray crystal structure of human isoform II in adduct with an adamantyl analogue of acetazolamide resides in a less utilized binding pocket than most hydrophobic inhibitors. |
| AID238575 | Inhibitory activity against human carbonic anhydrase IV (hCAIV) | 2005 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 15, Issue:4
| Carbonic anhydrase inhibitors. Inhibition of the membrane-bound human and bovine isozymes IV with sulfonamides. |
| AID244228 | Ratio of inhibitory potency against carbonic anhydrase II to that of inhibitory potency against carbonic anhydrase IX | 2005 | Bioorganic & medicinal chemistry letters, Jan-17, Volume: 15, Issue:2
| Carbonic anhydrase inhibitors. Novel sulfanilamide/acetazolamide derivatives obtained by the tail approach and their interaction with the cytosolic isozymes I and II, and the tumor-associated isozyme IX. |
| AID644379 | Inhibition of GST-tagged astrosclera willeyana Astrosclerin-3 expressed in Escherichia coli after 15 mins preincubation by stopped flow CO2 hydration assay | 2012 | Bioorganic & medicinal chemistry, Feb-15, Volume: 20, Issue:4
| Cloning, characterization and sulfonamide inhibition studies of an α-carbonic anhydrase from the living fossil sponge Astrosclera willeyana. |
| AID48132 | Inhibition constant against bovine Carbonic anhydrase IV, isolated from lung microsomes | 2003 | Journal of medicinal chemistry, May-22, Volume: 46, Issue:11
| Carbonic anhydrase inhibitors. Inhibition of tumor-associated isozyme IX by halogenosulfanilamide and halogenophenylaminobenzolamide derivatives. |
| AID1453410 | Inhibition of Francisella tularensis beta-carbonic anhydrase assessed as reduction in CO2 hydration preincubated for 15 mins followed by CO2 addition measured for 10 to 100 secs by stopped-flow assay | | | |
| AID669116 | Inhibition of Cryptococcus neoformans Can2 preincubated for 15 mins measured for 10 to 100 sec by stopped-flow method | 2012 | Journal of medicinal chemistry, Apr-12, Volume: 55, Issue:7
| Molecular cloning, characterization, and inhibition studies of a β-carbonic anhydrase from Malassezia globosa, a potential antidandruff target. |
| AID644380 | Inhibition of human recombinant carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration assay | 2012 | Bioorganic & medicinal chemistry, Feb-15, Volume: 20, Issue:4
| Cloning, characterization and sulfonamide inhibition studies of an α-carbonic anhydrase from the living fossil sponge Astrosclera willeyana. |
| AID1188138 | Inhibition of Porphyromonas gingivalis Gamma-carbonic anhydrase compound preincubated for 15 mins by stopped flow CO2 hydrase assay method | 2014 | Bioorganic & medicinal chemistry, Sep-01, Volume: 22, Issue:17
| Sulfonamide inhibition study of the carbonic anhydrases from the bacterial pathogen Porphyromonas gingivalis: the β-class (PgiCAb) versus the γ-class (PgiCA) enzymes. |
| AID1194027 | Inhibition of recombinant Porphyromonas gingivalis gamma-carbonic anhydrase by stopped flow CO2 hydrase assay | 2015 | Bioorganic & medicinal chemistry, Apr-15, Volume: 23, Issue:8
| Sulfonamide inhibition studies of the γ-carbonic anhydrase from the Antarctic cyanobacterium Nostoc commune. |
| AID427122 | Inhibition of Candida albicans recombinant Nce103 by stopped-flow CO2 hydration assay | 2009 | Bioorganic & medicinal chemistry, Jul-01, Volume: 17, Issue:13
| Carbonic anhydrase inhibitors. Inhibition and homology modeling studies of the fungal beta-carbonic anhydrase from Candida albicans with sulfonamides. |
| AID350904 | Inhibition of human carbonic anhydrase 1 by Lineweaver-Burke plot | 2009 | Bioorganic & medicinal chemistry, May-01, Volume: 17, Issue:9
| Effects of new 5-amino-1,3,4-thiadiazole-2-sulfonamide derivatives on human carbonic anhydrase isozymes. |
| AID1061067 | Inhibition of Porphyromonas gingivalis recombinant gamma-carbonic anhydrase preincubated for 15 mins by stopped flow CO2 hydration assay | 2014 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 24, Issue:1
| Sulfonamide inhibition studies of the δ-carbonic anhydrase from the diatom Thalassiosira weissflogii. |
| AID1291357 | Inhibition of recombinant human carbonic anhydrase 1 preincubated for 15 mins by stopped-flow CO2 hydration assay | 2016 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 26, Issue:8
| Comparison of the sulfonamide inhibition profiles of the α-, β- and γ-carbonic anhydrases from the pathogenic bacterium Vibrio cholerae. |
| AID568363 | Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by CO2 hydration stopped-flow assay | 2011 | Bioorganic & medicinal chemistry, Feb-15, Volume: 19, Issue:4
| Kinetic and docking studies of phenol-based inhibitors of carbonic anhydrase isoforms I, II, IX and XII evidence a new binding mode within the enzyme active site. |
| AID1291358 | Inhibition of recombinant human carbonic anhydrase 2 preincubated for 15 mins by stopped-flow CO2 hydration assay | 2016 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 26, Issue:8
| Comparison of the sulfonamide inhibition profiles of the α-, β- and γ-carbonic anhydrases from the pathogenic bacterium Vibrio cholerae. |
| AID239703 | Inhibitory constant against human carbonic anhydrase XIV in CO2 hydrase assay | 2005 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 15, Issue:17
| Carbonic anhydrase inhibitors: inhibition of the transmembrane isozyme XIV with sulfonamides. |
| AID48281 | Inhibitory activity against bovine lung microsomes carbonic anhydrase isozyme IV (bCA IV). | 1999 | Journal of medicinal chemistry, Jul-15, Volume: 42, Issue:14
| Carbonic anhydrase inhibitors. Synthesis of water-soluble, topically effective, intraocular pressure-lowering aromatic/heterocyclic sulfonamides containing cationic or anionic moieties: is the tail more important than the ring? |
| AID299249 | Inhibition of Helicobacter pylori alpha carbonic anhydrase by stopped-flow CO2 hydrase assay | 2007 | Bioorganic & medicinal chemistry letters, Jul-01, Volume: 17, Issue:13
| Carbonic anhydrase inhibitors: the beta-carbonic anhydrase from Helicobacter pylori is a new target for sulfonamide and sulfamate inhibitors. |
| AID568364 | Inhibition of human carbonic anhydrase 9 preincubated for 15 mins by CO2 hydration stopped-flow assay | 2011 | Bioorganic & medicinal chemistry, Feb-15, Volume: 19, Issue:4
| Kinetic and docking studies of phenol-based inhibitors of carbonic anhydrase isoforms I, II, IX and XII evidence a new binding mode within the enzyme active site. |
| AID350905 | Inhibition of human carbonic anhydrase 2 by Lineweaver-Burke plot | 2009 | Bioorganic & medicinal chemistry, May-01, Volume: 17, Issue:9
| Effects of new 5-amino-1,3,4-thiadiazole-2-sulfonamide derivatives on human carbonic anhydrase isozymes. |
| AID50367 | Inhibitory activity against human carbonic anhydrase I (CA1) | 2000 | Journal of medicinal chemistry, Jan-27, Volume: 43, Issue:2
| Carbonic anhydrase inhibitors: synthesis of membrane-impermeant low molecular weight sulfonamides possessing in vivo selectivity for the membrane-bound versus cytosolic isozymes. |
| AID743515 | Inhibition of human recombinant carbonic anhydrase 1 preincubated for 15 mins by CO2 hydration stopped-flow assay | 2013 | Bioorganic & medicinal chemistry, Mar-15, Volume: 21, Issue:6
| The alpha-carbonic anhydrase from the thermophilic bacterium Sulfurihydrogenibium yellowstonense YO3AOP1 is highly susceptible to inhibition by sulfonamides. |
| AID1240215 | Inhibition of Pseudoalteromonas haloplanktis gamma carbonic anhydrase by CO2 hydration assay | 2015 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 25, Issue:17
| Sulfonamide inhibition studies of the γ-carbonic anhydrase from the Antarctic bacterium Pseudoalteromonas haloplanktis. |
| AID48299 | Inhibition constant determined against catalytic domain of human cloned carbonic anhydrase IX | 2003 | Journal of medicinal chemistry, May-22, Volume: 46, Issue:11
| Carbonic anhydrase inhibitors. Inhibition of tumor-associated isozyme IX by halogenosulfanilamide and halogenophenylaminobenzolamide derivatives. |
| AID427125 | Inhibition of human recombinant carbonic anhydrase 1 by stopped-flow CO2 hydrase method | 2009 | Bioorganic & medicinal chemistry, Jul-01, Volume: 17, Issue:13
| Carbonic anhydrase inhibitors. Inhibition and homology modeling studies of the fungal beta-carbonic anhydrase from Candida albicans with sulfonamides. |
| AID301522 | Inhibition of human cloned carbonic anhydrase2 by CO2 hydration method | 2007 | Bioorganic & medicinal chemistry, Nov-15, Volume: 15, Issue:22
| Design, synthesis, and docking studies of new 1,3,4-thiadiazole-2-thione derivatives with carbonic anhydrase inhibitory activity. |
| AID238221 | Inhibitory constant against human Carbonic anhydrase II | 2005 | Bioorganic & medicinal chemistry letters, May-02, Volume: 15, Issue:9
| Carbonic anhydrase inhibitors. Inhibition of the cytosolic and tumor-associated carbonic anhydrase isozymes I, II, and IX with a series of 1,3,4-thiadiazole- and 1,2,4-triazole-thiols. |
| AID1796582 | CA Inhibition Assay from Article 10.1021/jm050483n: \\Carbonic anhydrase inhibitors. The mitochondrial isozyme VB as a new target for sulfonamide and sulfamate inhibitors.\\ | 2005 | Journal of medicinal chemistry, Dec-01, Volume: 48, Issue:24
| Carbonic anhydrase inhibitors. The mitochondrial isozyme VB as a new target for sulfonamide and sulfamate inhibitors. |
| AID1796552 | CA Inhibition Assay from Article 10.1021/jm0512600: \\Carbonic anhydrase inhibitors: DNA cloning and inhibition studies of the alpha-carbonic anhydrase from Helicobacter pylori, a new target for developing sulfonamide and sulfamate gastric drugs.\\ | 2006 | Journal of medicinal chemistry, Mar-23, Volume: 49, Issue:6
| Carbonic anhydrase inhibitors: DNA cloning and inhibition studies of the alpha-carbonic anhydrase from Helicobacter pylori, a new target for developing sulfonamide and sulfamate gastric drugs. |
| AID1796755 | CA Inhibition Assay from Article 10.1021/jm021123s: \\Carbonic anhydrase inhibitors. Inhibition of tumor-associated isozyme IX by halogenosulfanilamide and halogenophenylaminobenzolamide derivatives.\\ | 2003 | Journal of medicinal chemistry, May-22, Volume: 46, Issue:11
| Carbonic anhydrase inhibitors. Inhibition of tumor-associated isozyme IX by halogenosulfanilamide and halogenophenylaminobenzolamide derivatives. |
| AID1798769 | CA Inhibition Assay from Article 10.1021/jm801267c: \\Cloning, expression, post-translational modifications and inhibition studies on the latest mammalian carbonic anhydrase isoform, CA XV.\\ | 2009 | Journal of medicinal chemistry, Feb-12, Volume: 52, Issue:3
| Cloning, expression, post-translational modifications and inhibition studies on the latest mammalian carbonic anhydrase isoform, CA XV. |
| AID1802982 | Esterase Activity Assay from Article 10.3109/14756366.2010.491795: \\Synthesis of 5-amino-1,3,4-thiadiazole-2-sulphonamide derivatives and their inhibition effects on human carbonic anhydrase isozymes.\\ | 2011 | Journal of enzyme inhibition and medicinal chemistry, Apr, Volume: 26, Issue:2
| Synthesis of 5-amino-1,3,4-thiadiazole-2-sulphonamide derivatives and their inhibition effects on human carbonic anhydrase isozymes. |
| AID1798982 | CA Inhibition Assay from Article 10.1021/jm9003126: \\Carbonic anhydrase inhibitors. Cloning, characterization, and inhibition studies of a new beta-carbonic anhydrase from Mycobacterium tuberculosis.\\ | 2009 | Journal of medicinal chemistry, May-14, Volume: 52, Issue:9
| Carbonic anhydrase inhibitors. Cloning, characterization, and inhibition studies of a new beta-carbonic anhydrase from Mycobacterium tuberculosis. |
| AID1798985 | CA Inhibition Assay from Article 10.1021/jm9000488: \\Molecular cloning, characterization, and inhibition studies of the Rv1284 beta-carbonic anhydrase from Mycobacterium tuberculosis with sulfonamides and a sulfamate.\\ | 2009 | Journal of medicinal chemistry, Apr-23, Volume: 52, Issue:8
| Molecular cloning, characterization, and inhibition studies of the Rv1284 beta-carbonic anhydrase from Mycobacterium tuberculosis with sulfonamides and a sulfamate. |
| AID1802983 | Enzyme Activity Assay from Article 10.3109/14756366.2010.491795: \\Synthesis of 5-amino-1,3,4-thiadiazole-2-sulphonamide derivatives and their inhibition effects on human carbonic anhydrase isozymes.\\ | 2011 | Journal of enzyme inhibition and medicinal chemistry, Apr, Volume: 26, Issue:2
| Synthesis of 5-amino-1,3,4-thiadiazole-2-sulphonamide derivatives and their inhibition effects on human carbonic anhydrase isozymes. |
| AID1799266 | CA Inhibition Assay from Article 10.1016/j.bmc.2009.05.002: \\Carbonic anhydrase inhibitors. Inhibition and homology modeling studies of the fungal beta-carbonic anhydrase from Candida albicans with sulfonamides.\\ | 2009 | Bioorganic & medicinal chemistry, Jul-01, Volume: 17, Issue:13
| Carbonic anhydrase inhibitors. Inhibition and homology modeling studies of the fungal beta-carbonic anhydrase from Candida albicans with sulfonamides. |
| AID1802981 | Hydratase Activity Assay from Article 10.3109/14756366.2010.491795: \\Synthesis of 5-amino-1,3,4-thiadiazole-2-sulphonamide derivatives and their inhibition effects on human carbonic anhydrase isozymes.\\ | 2011 | Journal of enzyme inhibition and medicinal chemistry, Apr, Volume: 26, Issue:2
| Synthesis of 5-amino-1,3,4-thiadiazole-2-sulphonamide derivatives and their inhibition effects on human carbonic anhydrase isozymes. |
| AID1799602 | In Vitro Inhibtion Assay from Article 10.1111/j.1747-0285.2010.01036.x: \\An alternative purification method for human serum paraoxonase 1 and its interactions with sulfonamides.\\ | 2010 | Chemical biology & drug design, Dec, Volume: 76, Issue:6
| An alternative purification method for human serum paraoxonase 1 and its interactions with sulfonamides. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |