| Assay ID | Title | Year | Journal | Article |
|---|
| AID232721 | Selectivity ratio of alpha1/alpha2d | 2000 | Journal of medicinal chemistry, Mar-09, Volume: 43, Issue:5
| alpha(2) Adrenoceptor agonists as potential analgesic agents. 2. Discovery of 4-(4-Imidazo)-1,3-dimethyl-6,7-dihydrothianaphthene [corrected] as a high-affinity ligand for the alpha(2D) adrenergic receptor. |
| AID223928 | potential antinociceptive activity initially at a screening dose of 30 mg/kg po in the mouse abdominal irritant test(MAIT) using acetylcholine bromide as irritant | 2000 | Journal of medicinal chemistry, Apr-06, Volume: 43, Issue:7
| Alpha(2) adrenoceptor agonists as potential analgesic agents. 2. Discovery of 4-(4-imidazo)-1,3-dimethyl-6,7-dihydro-thianaphthene as a high-affinity ligand for the alpha(2D) adrenergic receptor. |
| AID225677 | Peroral ED50 value was measured using mouse abdominal irritant test(MAIT) | 2000 | Journal of medicinal chemistry, Apr-06, Volume: 43, Issue:7
| Alpha(2) adrenoceptor agonists as potential analgesic agents. 2. Discovery of 4-(4-imidazo)-1,3-dimethyl-6,7-dihydro-thianaphthene as a high-affinity ligand for the alpha(2D) adrenergic receptor. |
| AID131765 | Tested for hot plate assay at 48 degrees Celsius in mouse after peroral administration | 2000 | Journal of medicinal chemistry, Mar-09, Volume: 43, Issue:5
| alpha(2) Adrenoceptor agonists as potential analgesic agents. 2. Discovery of 4-(4-Imidazo)-1,3-dimethyl-6,7-dihydrothianaphthene [corrected] as a high-affinity ligand for the alpha(2D) adrenergic receptor. |
| AID36229 | Binding affinity towards Alpha-2B adrenergic receptor | 2000 | Journal of medicinal chemistry, Mar-09, Volume: 43, Issue:5
| alpha(2) Adrenoceptor agonists as potential analgesic agents. 2. Discovery of 4-(4-Imidazo)-1,3-dimethyl-6,7-dihydrothianaphthene [corrected] as a high-affinity ligand for the alpha(2D) adrenergic receptor. |
| AID36551 | Binding affinity towards alpha-2D adrenergic receptor | 2000 | Journal of medicinal chemistry, Mar-09, Volume: 43, Issue:5
| alpha(2) Adrenoceptor agonists as potential analgesic agents. 2. Discovery of 4-(4-Imidazo)-1,3-dimethyl-6,7-dihydrothianaphthene [corrected] as a high-affinity ligand for the alpha(2D) adrenergic receptor. |
| AID35950 | Binding affinity towards Alpha-2A adrenergic receptor | 2000 | Journal of medicinal chemistry, Mar-09, Volume: 43, Issue:5
| alpha(2) Adrenoceptor agonists as potential analgesic agents. 2. Discovery of 4-(4-Imidazo)-1,3-dimethyl-6,7-dihydrothianaphthene [corrected] as a high-affinity ligand for the alpha(2D) adrenergic receptor. |
| AID35422 | Tested for Binding affinity towards alpha-1 adrenergic receptor | 2000 | Journal of medicinal chemistry, Mar-09, Volume: 43, Issue:5
| alpha(2) Adrenoceptor agonists as potential analgesic agents. 2. Discovery of 4-(4-Imidazo)-1,3-dimethyl-6,7-dihydrothianaphthene [corrected] as a high-affinity ligand for the alpha(2D) adrenergic receptor. |
| AID36543 | in vitro alpha-2C adrenergic receptor binding assay from rats, using RX 821002 as the displaceable ligand | 2000 | Journal of medicinal chemistry, Apr-06, Volume: 43, Issue:7
| Alpha(2) adrenoceptor agonists as potential analgesic agents. 2. Discovery of 4-(4-imidazo)-1,3-dimethyl-6,7-dihydro-thianaphthene as a high-affinity ligand for the alpha(2D) adrenergic receptor. |
| AID176826 | Tested for antinociceptive activity at a screening dose of 30 mg/kg, po in the rat air-induced abdominal irritant test (RAIT) using acetylcholine as irritant | 2000 | Journal of medicinal chemistry, Mar-09, Volume: 43, Issue:5
| alpha(2) Adrenoceptor agonists as potential analgesic agents. 2. Discovery of 4-(4-Imidazo)-1,3-dimethyl-6,7-dihydrothianaphthene [corrected] as a high-affinity ligand for the alpha(2D) adrenergic receptor. |
| AID225676 | Peroral ED50 value was measured using mouse 48 degree hot plate test | 2000 | Journal of medicinal chemistry, Apr-06, Volume: 43, Issue:7
| Alpha(2) adrenoceptor agonists as potential analgesic agents. 2. Discovery of 4-(4-imidazo)-1,3-dimethyl-6,7-dihydro-thianaphthene as a high-affinity ligand for the alpha(2D) adrenergic receptor. |
| AID133237 | Tested for antinociceptive activity at a screening dose of 30 mg/kg, po in the mouse abdominal irritant test (MAIT) using acetylcholine as irritant. | 2000 | Journal of medicinal chemistry, Mar-09, Volume: 43, Issue:5
| alpha(2) Adrenoceptor agonists as potential analgesic agents. 2. Discovery of 4-(4-Imidazo)-1,3-dimethyl-6,7-dihydrothianaphthene [corrected] as a high-affinity ligand for the alpha(2D) adrenergic receptor. |
| AID176494 | Compound has been examined as a abdominal irritant in rat after peroral administration | 2000 | Journal of medicinal chemistry, Mar-09, Volume: 43, Issue:5
| alpha(2) Adrenoceptor agonists as potential analgesic agents. 2. Discovery of 4-(4-Imidazo)-1,3-dimethyl-6,7-dihydrothianaphthene [corrected] as a high-affinity ligand for the alpha(2D) adrenergic receptor. |
| AID225282 | ED50 value was measured using rat air-induced abdominal irritant test(RAIT) | 2000 | Journal of medicinal chemistry, Apr-06, Volume: 43, Issue:7
| Alpha(2) adrenoceptor agonists as potential analgesic agents. 2. Discovery of 4-(4-imidazo)-1,3-dimethyl-6,7-dihydro-thianaphthene as a high-affinity ligand for the alpha(2D) adrenergic receptor. |
| AID131945 | Tested for tail flick assay in mouse after peroral administration | 2000 | Journal of medicinal chemistry, Mar-09, Volume: 43, Issue:5
| alpha(2) Adrenoceptor agonists as potential analgesic agents. 2. Discovery of 4-(4-Imidazo)-1,3-dimethyl-6,7-dihydrothianaphthene [corrected] as a high-affinity ligand for the alpha(2D) adrenergic receptor. |
| AID129476 | Compound has been examined as a abdominal irritant in mouse after peroral administration | 2000 | Journal of medicinal chemistry, Mar-09, Volume: 43, Issue:5
| alpha(2) Adrenoceptor agonists as potential analgesic agents. 2. Discovery of 4-(4-Imidazo)-1,3-dimethyl-6,7-dihydrothianaphthene [corrected] as a high-affinity ligand for the alpha(2D) adrenergic receptor. |
| AID36555 | In vitro rat alpha-2D adrenergic receptor binding using p-aminoclonidine | 2000 | Journal of medicinal chemistry, Apr-06, Volume: 43, Issue:7
| Alpha(2) adrenoceptor agonists as potential analgesic agents. 2. Discovery of 4-(4-imidazo)-1,3-dimethyl-6,7-dihydro-thianaphthene as a high-affinity ligand for the alpha(2D) adrenergic receptor. |
| AID225678 | Peroral ED50 value was measured using mouse tail flick test | 2000 | Journal of medicinal chemistry, Apr-06, Volume: 43, Issue:7
| Alpha(2) adrenoceptor agonists as potential analgesic agents. 2. Discovery of 4-(4-imidazo)-1,3-dimethyl-6,7-dihydro-thianaphthene as a high-affinity ligand for the alpha(2D) adrenergic receptor. |
| AID35373 | in vitro alpha-1 adrenergic receptor binding assay from rats, using RX 821002 as the displaceable ligand | 2000 | Journal of medicinal chemistry, Apr-06, Volume: 43, Issue:7
| Alpha(2) adrenoceptor agonists as potential analgesic agents. 2. Discovery of 4-(4-imidazo)-1,3-dimethyl-6,7-dihydro-thianaphthene as a high-affinity ligand for the alpha(2D) adrenergic receptor. |
| AID36094 | in vitro alpha-2A adrenergic receptor binding assay from rats, using RX 821002 as the displaceable ligand | 2000 | Journal of medicinal chemistry, Apr-06, Volume: 43, Issue:7
| Alpha(2) adrenoceptor agonists as potential analgesic agents. 2. Discovery of 4-(4-imidazo)-1,3-dimethyl-6,7-dihydro-thianaphthene as a high-affinity ligand for the alpha(2D) adrenergic receptor. |
| AID36375 | in vitro alpha-2B adrenergic receptor binding assay from rats, using RX 821002 as the displaceable ligand | 2000 | Journal of medicinal chemistry, Apr-06, Volume: 43, Issue:7
| Alpha(2) adrenoceptor agonists as potential analgesic agents. 2. Discovery of 4-(4-imidazo)-1,3-dimethyl-6,7-dihydro-thianaphthene as a high-affinity ligand for the alpha(2D) adrenergic receptor. |
| AID1296008 | Cytotoxic Profiling of Annotated Libraries Using Quantitative High-Throughput Screening | 2020 | SLAS discovery : advancing life sciences R & D, 01, Volume: 25, Issue:1
| Cytotoxic Profiling of Annotated and Diverse Chemical Libraries Using Quantitative High-Throughput Screening. |
| AID1347159 | Primary screen GU Rhodamine qHTS for Zika virus inhibitors: Unlinked NS2B-NS3 protease assay | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1346987 | P-glycoprotein substrates identified in KB-8-5-11 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5
| A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
| AID1347160 | Primary screen NINDS Rhodamine qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1346986 | P-glycoprotein substrates identified in KB-3-1 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5
| A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |