| Assay ID | Title | Year | Journal | Article |
|---|
| AID239126 | Inhibitory constant against catalytic domain of human carbonic anhydrase XII | 2005 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 15, Issue:17
| Carbonic anhydrase inhibitors: inhibition of the transmembrane isozyme XIV with sulfonamides. |
| AID47736 | In vitro inhibition of human Carbonic Anhydrase II | 1989 | Journal of medicinal chemistry, Nov, Volume: 32, Issue:11
| Topically active carbonic anhydrase inhibitors. 1. O-acyl derivatives of 6-hydroxybenzothiazole-2-sulfonamide. |
| AID48296 | Inhibitory activity against human tumor-associated transmembrane carbonic anhydrase IX. | 2004 | Bioorganic & medicinal chemistry letters, Jun-21, Volume: 14, Issue:12
| Carbonic anhydrase inhibitors: the first QSAR study on inhibition of tumor-associated isoenzyme IX with aromatic and heterocyclic sulfonamides. |
| AID369273 | Inhibition of human full length recombinant carbonic anhydrase 6 by stopped flow CO2 hydrase assay | 2009 | Journal of medicinal chemistry, Feb-12, Volume: 52, Issue:3
| Cloning, expression, post-translational modifications and inhibition studies on the latest mammalian carbonic anhydrase isoform, CA XV. |
| AID50172 | Compound was tested for relative in vitro carbonic anhydrase activity from human red blood cell. | 1984 | Journal of medicinal chemistry, Jun, Volume: 27, Issue:6
| Topical carbonic anhydrase inhibitors. |
| AID256965 | Inhibitory activity against human recombinant mitochondrial isozyme CA VB | 2005 | Journal of medicinal chemistry, Dec-01, Volume: 48, Issue:24
| Carbonic anhydrase inhibitors. The mitochondrial isozyme VB as a new target for sulfonamide and sulfamate inhibitors. |
| AID743515 | Inhibition of human recombinant carbonic anhydrase 1 preincubated for 15 mins by CO2 hydration stopped-flow assay | 2013 | Bioorganic & medicinal chemistry, Mar-15, Volume: 21, Issue:6
| The alpha-carbonic anhydrase from the thermophilic bacterium Sulfurihydrogenibium yellowstonense YO3AOP1 is highly susceptible to inhibition by sulfonamides. |
| AID50369 | Inhibition of human cloned Carbonic anhydrase I (hCA I,cytosolic form) | 1999 | Journal of medicinal chemistry, Jul-15, Volume: 42, Issue:14
| Carbonic anhydrase inhibitors. Synthesis of water-soluble, topically effective, intraocular pressure-lowering aromatic/heterocyclic sulfonamides containing cationic or anionic moieties: is the tail more important than the ring? |
| AID644381 | Inhibition of human recombinant carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration assay | 2012 | Bioorganic & medicinal chemistry, Feb-15, Volume: 20, Issue:4
| Cloning, characterization and sulfonamide inhibition studies of an α-carbonic anhydrase from the living fossil sponge Astrosclera willeyana. |
| AID166312 | Intraocular pressure was measured in rabbit following topical instillation at different time intervals after dosing. | 1984 | Journal of medicinal chemistry, Jun, Volume: 27, Issue:6
| Topical carbonic anhydrase inhibitors. |
| AID369271 | Inhibition of human recombinant carbonic anhydrase 1 by stopped flow CO2 hydrase assay | 2009 | Journal of medicinal chemistry, Feb-12, Volume: 52, Issue:3
| Cloning, expression, post-translational modifications and inhibition studies on the latest mammalian carbonic anhydrase isoform, CA XV. |
| AID711212 | Inhibition of recombinant Vibrio cholerae carbonic anhydrase expressed in Escherichia coli (DE3) preincubated for 15 mins by stopped-flow CO2 hydrase assay | 2012 | Journal of medicinal chemistry, Dec-13, Volume: 55, Issue:23
| DNA cloning, characterization, and inhibition studies of an α-carbonic anhydrase from the pathogenic bacterium Vibrio cholerae. |
| AID644379 | Inhibition of GST-tagged astrosclera willeyana Astrosclerin-3 expressed in Escherichia coli after 15 mins preincubation by stopped flow CO2 hydration assay | 2012 | Bioorganic & medicinal chemistry, Feb-15, Volume: 20, Issue:4
| Cloning, characterization and sulfonamide inhibition studies of an α-carbonic anhydrase from the living fossil sponge Astrosclera willeyana. |
| AID48300 | Inhibitory activity against human cloned carbonic anhydrase isozyme IX, by CO2 hydrase assay method. | 2003 | Bioorganic & medicinal chemistry letters, Mar-24, Volume: 13, Issue:6
| Carbonic anhydrase inhibitors: inhibition of the tumor-associated isozyme IX with aromatic and heterocyclic sulfonamides. |
| AID577531 | Inhibition of Brucella suis carbonic anhydrase I by spectrophotometry at pH 8.3 | 2011 | Bioorganic & medicinal chemistry, Feb-01, Volume: 19, Issue:3
| A new β-carbonic anhydrase from Brucella suis, its cloning, characterization, and inhibition with sulfonamides and sulfamates, leading to impaired pathogen growth. |
| AID261580 | Inhibition of human recombinant carbonic anhydrase 2 by stopped-flow CO2 hydrase assay | 2006 | Journal of medicinal chemistry, Mar-23, Volume: 49, Issue:6
| Carbonic anhydrase inhibitors: DNA cloning and inhibition studies of the alpha-carbonic anhydrase from Helicobacter pylori, a new target for developing sulfonamide and sulfamate gastric drugs. |
| AID48279 | Inhibitory activity against bovine carbonic anhydrase IV (CA4), isolated from bovine lung microsomes | 2000 | Journal of medicinal chemistry, Jan-27, Volume: 43, Issue:2
| Carbonic anhydrase inhibitors: synthesis of membrane-impermeant low molecular weight sulfonamides possessing in vivo selectivity for the membrane-bound versus cytosolic isozymes. |
| AID261582 | Selectivity ratio for human carbonic anhydrase 2 over Helicobacter pylori carbonic anhydrase | 2006 | Journal of medicinal chemistry, Mar-23, Volume: 49, Issue:6
| Carbonic anhydrase inhibitors: DNA cloning and inhibition studies of the alpha-carbonic anhydrase from Helicobacter pylori, a new target for developing sulfonamide and sulfamate gastric drugs. |
| AID459696 | Inhibition of Brucella suis CA1 expressed in Escherichia coli BL21(DE3) by stopped-flow CO2-hydration assay | 2010 | Journal of medicinal chemistry, Mar-11, Volume: 53, Issue:5
| Cloning, characterization, and inhibition studies of a beta-carbonic anhydrase from Brucella suis. |
| AID612725 | Inhibition of human recombinant carbonic anhydrase 1 at pH 7.5 by stopped flow CO2 hydration assay | 2011 | Bioorganic & medicinal chemistry, Aug-15, Volume: 19, Issue:16
| Inhibition studies of the β-carbonic anhydrases from the bacterial pathogen Salmonella enterica serovar Typhimurium with sulfonamides and sulfamates. |
| AID577527 | Inhibition of human carbonic anhydrase II by spectrophotometry at pH 7.5 | 2011 | Bioorganic & medicinal chemistry, Feb-01, Volume: 19, Issue:3
| A new β-carbonic anhydrase from Brucella suis, its cloning, characterization, and inhibition with sulfonamides and sulfamates, leading to impaired pathogen growth. |
| AID166789 | Corneal penetration rate constant (k) for excised denuded cornea of albino rabbit. Ranges from 17.8-19.0 | 1989 | Journal of medicinal chemistry, Nov, Volume: 32, Issue:11
| Topically active carbonic anhydrase inhibitors. 1. O-acyl derivatives of 6-hydroxybenzothiazole-2-sulfonamide. |
| AID256964 | Inhibitory activity against human recombinant mitochondrial isozyme CA VA | 2005 | Journal of medicinal chemistry, Dec-01, Volume: 48, Issue:24
| Carbonic anhydrase inhibitors. The mitochondrial isozyme VB as a new target for sulfonamide and sulfamate inhibitors. |
| AID263638 | Inhibition of Helicobacter pylori recombinant CA | 2006 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 16, Issue:8
| Carbonic anhydrase inhibitors: cloning and sulfonamide inhibition studies of a carboxyterminal truncated alpha-carbonic anhydrase from Helicobacter pylori. |
| AID261581 | Inhibition of Helicobacter pylori recombinant carbonic anhydrase by stopped-flow CO2 hydrase assay | 2006 | Journal of medicinal chemistry, Mar-23, Volume: 49, Issue:6
| Carbonic anhydrase inhibitors: DNA cloning and inhibition studies of the alpha-carbonic anhydrase from Helicobacter pylori, a new target for developing sulfonamide and sulfamate gastric drugs. |
| AID1268965 | Inhibition of recombinant Thiomicrospira crunogena XCL-2 carbonic anhydrase by stopped flow CO2 hydrase assay | 2016 | Bioorganic & medicinal chemistry letters, Jan-15, Volume: 26, Issue:2
| Sulfonamide inhibition studies of the α-carbonic anhydrase from the gammaproteobacterium Thiomicrospira crunogena XCL-2, TcruCA. |
| AID25106 | Acid dissociation constant was determined. | 1984 | Journal of medicinal chemistry, Jun, Volume: 27, Issue:6
| Topical carbonic anhydrase inhibitors. |
| AID48122 | Inhibitory activity against bovine carbonic anhydrase IV | 2002 | Journal of medicinal chemistry, Mar-28, Volume: 45, Issue:7
| Carbonic anhydrase inhibitors. A general approach for the preparation of water-soluble sulfonamides incorporating polyamino-polycarboxylate tails and of their metal complexes possessing long-lasting, topical intraocular pressure-lowering properties. |
| AID48280 | Inhibitory activity against bovine carbonic anhydrase isozyme IV isolated from bovine lung microsomes, by esterase assay method. | 2003 | Bioorganic & medicinal chemistry letters, Mar-24, Volume: 13, Issue:6
| Carbonic anhydrase inhibitors: inhibition of the tumor-associated isozyme IX with aromatic and heterocyclic sulfonamides. |
| AID47901 | Inhibitory activity against Human carbonic anhydrase II | 2002 | Journal of medicinal chemistry, Mar-28, Volume: 45, Issue:7
| Carbonic anhydrase inhibitors. A general approach for the preparation of water-soluble sulfonamides incorporating polyamino-polycarboxylate tails and of their metal complexes possessing long-lasting, topical intraocular pressure-lowering properties. |
| AID239703 | Inhibitory constant against human carbonic anhydrase XIV in CO2 hydrase assay | 2005 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 15, Issue:17
| Carbonic anhydrase inhibitors: inhibition of the transmembrane isozyme XIV with sulfonamides. |
| AID275806 | Inhibition of full length human recombinant CA VI | 2007 | Journal of medicinal chemistry, Jan-25, Volume: 50, Issue:2
| Carbonic anhydrase inhibitors. DNA cloning, characterization, and inhibition studies of the human secretory isoform VI, a new target for sulfonamide and sulfamate inhibitors. |
| AID743514 | Inhibition of human recombinant carbonic anhydrase 2 preincubated for 15 mins by CO2 hydration stopped-flow assay | 2013 | Bioorganic & medicinal chemistry, Mar-15, Volume: 21, Issue:6
| The alpha-carbonic anhydrase from the thermophilic bacterium Sulfurihydrogenibium yellowstonense YO3AOP1 is highly susceptible to inhibition by sulfonamides. |
| AID263048 | Inhibition of human CA1 | 2006 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 16, Issue:7
| QSAR study on topically acting sulfonamides incorporating GABA moieties: a molecular connectivity approach. |
| AID239102 | Inhibitory constant against catalytic domain of human carbonic anhydrase IX | 2005 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 15, Issue:17
| Carbonic anhydrase inhibitors: inhibition of the transmembrane isozyme XIV with sulfonamides. |
| AID369275 | Inhibition of mouse recombinant carbonic anhydrase 15 by stopped flow CO2 hydrase assay | 2009 | Journal of medicinal chemistry, Feb-12, Volume: 52, Issue:3
| Cloning, expression, post-translational modifications and inhibition studies on the latest mammalian carbonic anhydrase isoform, CA XV. |
| AID222126 | Inhibition of cloned isozyme, human carbonic anhydrase II | 2001 | Bioorganic & medicinal chemistry letters, Feb-26, Volume: 11, Issue:4
| Carbonic anhydrase inhibitors: synthesis of sulfonamides incorporating dtpa tails and of their zinc complexes with powerful topical antiglaucoma properties. |
| AID20165 | In vitro susceptibility to nucleophilic attack by reduced glutathione at 37 degree C and at pH 7.4 | 1989 | Journal of medicinal chemistry, Nov, Volume: 32, Issue:11
| Topically active carbonic anhydrase inhibitors. 1. O-acyl derivatives of 6-hydroxybenzothiazole-2-sulfonamide. |
| AID743513 | Inhibition of Helicobacter pylori recombinant alpha carbonic anhydrase preincubated for 15 mins by CO2 hydration stopped-flow assay | 2013 | Bioorganic & medicinal chemistry, Mar-15, Volume: 21, Issue:6
| The alpha-carbonic anhydrase from the thermophilic bacterium Sulfurihydrogenibium yellowstonense YO3AOP1 is highly susceptible to inhibition by sulfonamides. |
| AID263049 | Inhibition of human CA2 | 2006 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 16, Issue:7
| QSAR study on topically acting sulfonamides incorporating GABA moieties: a molecular connectivity approach. |
| AID166791 | Corneal penetration rate constant (k) for excised intact cornea of albino rabbit.; Range is from 1.8-2.2 | 1989 | Journal of medicinal chemistry, Nov, Volume: 32, Issue:11
| Topically active carbonic anhydrase inhibitors. 1. O-acyl derivatives of 6-hydroxybenzothiazole-2-sulfonamide. |
| AID48284 | Inhibitory activity against bovine carbonic anhydrase IV (CA4), isolated from bovine lung microsomes | 1999 | Journal of medicinal chemistry, Sep-09, Volume: 42, Issue:18
| Carbonic anhydrase inhibitors: synthesis of water-soluble, aminoacyl/dipeptidyl sulfonamides possessing long-lasting intraocular pressure-lowering properties via the topical route. |
| AID612731 | Inhibition of Salmonella Typhimurium recombinant carbonic anhydrase 1 at pH 8.3 by stopped flow CO2 hydration assay | 2011 | Bioorganic & medicinal chemistry, Aug-15, Volume: 19, Issue:16
| Inhibition studies of the β-carbonic anhydrases from the bacterial pathogen Salmonella enterica serovar Typhimurium with sulfonamides and sulfamates. |
| AID299250 | Inhibition of Helicobacter pylori beta carbonic anhydrase by stopped-flow CO2 hydrase assay | 2007 | Bioorganic & medicinal chemistry letters, Jul-01, Volume: 17, Issue:13
| Carbonic anhydrase inhibitors: the beta-carbonic anhydrase from Helicobacter pylori is a new target for sulfonamide and sulfamate inhibitors. |
| AID1268964 | Inhibition of recombinant Sulfurihydrogenibium yellowstonense YO3AOP1 carbonic anhydrase by stopped flow CO2 hydrase assay | 2016 | Bioorganic & medicinal chemistry letters, Jan-15, Volume: 26, Issue:2
| Sulfonamide inhibition studies of the α-carbonic anhydrase from the gammaproteobacterium Thiomicrospira crunogena XCL-2, TcruCA. |
| AID299243 | Inhibition of human carbonic anhydrase 2 by stopped-flow CO2 hydrase assay | 2007 | Bioorganic & medicinal chemistry letters, Jul-01, Volume: 17, Issue:13
| Carbonic anhydrase inhibitors: the beta-carbonic anhydrase from Helicobacter pylori is a new target for sulfonamide and sulfamate inhibitors. |
| AID222125 | Inhibition of cloned isozyme, human carbonic anhydrase I | 2001 | Bioorganic & medicinal chemistry letters, Feb-26, Volume: 11, Issue:4
| Carbonic anhydrase inhibitors: synthesis of sulfonamides incorporating dtpa tails and of their zinc complexes with powerful topical antiglaucoma properties. |
| AID275808 | Inhibition of human recombinant cytosolic isozyme CA II by stopped-flow CO2 hydrase method | 2007 | Journal of medicinal chemistry, Jan-25, Volume: 50, Issue:2
| Carbonic anhydrase inhibitors. DNA cloning, characterization, and inhibition studies of the human secretory isoform VI, a new target for sulfonamide and sulfamate inhibitors. |
| AID299242 | Inhibition of human carbonic anhydrase 1 by stopped-flow CO2 hydrase assay | 2007 | Bioorganic & medicinal chemistry letters, Jul-01, Volume: 17, Issue:13
| Carbonic anhydrase inhibitors: the beta-carbonic anhydrase from Helicobacter pylori is a new target for sulfonamide and sulfamate inhibitors. |
| AID1268962 | Inhibition of recombinant human carbonic anhydrase-1 by stopped flow CO2 hydrase assay | 2016 | Bioorganic & medicinal chemistry letters, Jan-15, Volume: 26, Issue:2
| Sulfonamide inhibition studies of the α-carbonic anhydrase from the gammaproteobacterium Thiomicrospira crunogena XCL-2, TcruCA. |
| AID369274 | Inhibition of human recombinant carbonic anhydrase 9 catalytic domain by stopped flow CO2 hydrase assay | 2009 | Journal of medicinal chemistry, Feb-12, Volume: 52, Issue:3
| Cloning, expression, post-translational modifications and inhibition studies on the latest mammalian carbonic anhydrase isoform, CA XV. |
| AID263637 | Inhibition of human recombinant CA2 | 2006 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 16, Issue:8
| Carbonic anhydrase inhibitors: cloning and sulfonamide inhibition studies of a carboxyterminal truncated alpha-carbonic anhydrase from Helicobacter pylori. |
| AID263636 | Inhibition of human recombinant CA1 | 2006 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 16, Issue:8
| Carbonic anhydrase inhibitors: cloning and sulfonamide inhibition studies of a carboxyterminal truncated alpha-carbonic anhydrase from Helicobacter pylori. |
| AID238300 | Ki value against human carbonic anhydrase II (hCA II) | 2005 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 15, Issue:4
| Carbonic anhydrase inhibitors. Inhibition of the transmembrane isozyme XII with sulfonamides-a new target for the design of antitumor and antiglaucoma drugs? |
| AID47936 | Inhibition of human carbonic anhydrase II | 2003 | Bioorganic & medicinal chemistry letters, Mar-24, Volume: 13, Issue:6
| Carbonic anhydrase inhibitors: inhibition of the tumor-associated isozyme IX with aromatic and heterocyclic sulfonamides. |
| AID261579 | Inhibition of human recombinant carbonic anhydrase 1 by stopped-flow CO2 hydrase assay | 2006 | Journal of medicinal chemistry, Mar-23, Volume: 49, Issue:6
| Carbonic anhydrase inhibitors: DNA cloning and inhibition studies of the alpha-carbonic anhydrase from Helicobacter pylori, a new target for developing sulfonamide and sulfamate gastric drugs. |
| AID47939 | Inhibitory activity against human recombinant carbonic anhydrase II (CA2) | 1999 | Journal of medicinal chemistry, Sep-09, Volume: 42, Issue:18
| Carbonic anhydrase inhibitors: synthesis of water-soluble, aminoacyl/dipeptidyl sulfonamides possessing long-lasting intraocular pressure-lowering properties via the topical route. |
| AID743512 | Inhibition of Sulfurihydrogenibium yellowstonense YO3AOP1 recombinant carbonic anhydrase preincubated for 15 mins by CO2 hydration stopped-flow assay | 2013 | Bioorganic & medicinal chemistry, Mar-15, Volume: 21, Issue:6
| The alpha-carbonic anhydrase from the thermophilic bacterium Sulfurihydrogenibium yellowstonense YO3AOP1 is highly susceptible to inhibition by sulfonamides. |
| AID48281 | Inhibitory activity against bovine lung microsomes carbonic anhydrase isozyme IV (bCA IV). | 1999 | Journal of medicinal chemistry, Jul-15, Volume: 42, Issue:14
| Carbonic anhydrase inhibitors. Synthesis of water-soluble, topically effective, intraocular pressure-lowering aromatic/heterocyclic sulfonamides containing cationic or anionic moieties: is the tail more important than the ring? |
| AID21709 | Solubility at a pH 7.2 phosphate buffer, 37 degrees celsius (N=6) | 1984 | Journal of medicinal chemistry, Jun, Volume: 27, Issue:6
| Topical carbonic anhydrase inhibitors. |
| AID26308 | Compound was tested for Octanol / pH 7.2 phosphate buffer distribution coefficient (N=2-3) | 1984 | Journal of medicinal chemistry, Jun, Volume: 27, Issue:6
| Topical carbonic anhydrase inhibitors. |
| AID263050 | Inhibition of bovine CA4 | 2006 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 16, Issue:7
| QSAR study on topically acting sulfonamides incorporating GABA moieties: a molecular connectivity approach. |
| AID238316 | Ki value against human carbonic anhydrase XII (hCA XII) | 2005 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 15, Issue:4
| Carbonic anhydrase inhibitors. Inhibition of the transmembrane isozyme XII with sulfonamides-a new target for the design of antitumor and antiglaucoma drugs? |
| AID50374 | Inhibitory activity against human recombinant carbonic anhydrase I (CA1) | 1999 | Journal of medicinal chemistry, Sep-09, Volume: 42, Issue:18
| Carbonic anhydrase inhibitors: synthesis of water-soluble, aminoacyl/dipeptidyl sulfonamides possessing long-lasting intraocular pressure-lowering properties via the topical route. |
| AID1268963 | Inhibition of recombinant human carbonic anhydrase-2 by stopped flow CO2 hydrase assay | 2016 | Bioorganic & medicinal chemistry letters, Jan-15, Volume: 26, Issue:2
| Sulfonamide inhibition studies of the α-carbonic anhydrase from the gammaproteobacterium Thiomicrospira crunogena XCL-2, TcruCA. |
| AID47934 | Inhibitory activity against human cloned Carbonic anhydrase II (hCA II, cytosolic form). | 1999 | Journal of medicinal chemistry, Jul-15, Volume: 42, Issue:14
| Carbonic anhydrase inhibitors. Synthesis of water-soluble, topically effective, intraocular pressure-lowering aromatic/heterocyclic sulfonamides containing cationic or anionic moieties: is the tail more important than the ring? |
| AID21281 | Corneal permeability coefficient was determined. | 1984 | Journal of medicinal chemistry, Jun, Volume: 27, Issue:6
| Topical carbonic anhydrase inhibitors. |
| AID275807 | Inhibition of human recombinant cytosolic isozyme CA I by stopped-flow CO2 hydrase method | 2007 | Journal of medicinal chemistry, Jan-25, Volume: 50, Issue:2
| Carbonic anhydrase inhibitors. DNA cloning, characterization, and inhibition studies of the human secretory isoform VI, a new target for sulfonamide and sulfamate inhibitors. |
| AID577530 | Inhibition of Brucella suis carbonic anhydrase II by spectrophotometry at pH 8.3 | 2011 | Bioorganic & medicinal chemistry, Feb-01, Volume: 19, Issue:3
| A new β-carbonic anhydrase from Brucella suis, its cloning, characterization, and inhibition with sulfonamides and sulfamates, leading to impaired pathogen growth. |
| AID256963 | Inhibitory activity against human recombinant cytosolic CA2 | 2005 | Journal of medicinal chemistry, Dec-01, Volume: 48, Issue:24
| Carbonic anhydrase inhibitors. The mitochondrial isozyme VB as a new target for sulfonamide and sulfamate inhibitors. |
| AID612726 | Inhibition of human recombinant carbonic anhydrase 2 at pH 7.5 by stopped flow CO2 hydration assay | 2011 | Bioorganic & medicinal chemistry, Aug-15, Volume: 19, Issue:16
| Inhibition studies of the β-carbonic anhydrases from the bacterial pathogen Salmonella enterica serovar Typhimurium with sulfonamides and sulfamates. |
| AID299249 | Inhibition of Helicobacter pylori alpha carbonic anhydrase by stopped-flow CO2 hydrase assay | 2007 | Bioorganic & medicinal chemistry letters, Jul-01, Volume: 17, Issue:13
| Carbonic anhydrase inhibitors: the beta-carbonic anhydrase from Helicobacter pylori is a new target for sulfonamide and sulfamate inhibitors. |
| AID612732 | Inhibition of Salmonella Typhimurium recombinant carbonic anhydrase 2 at pH 8.3 by stopped flow CO2 hydration assay | 2011 | Bioorganic & medicinal chemistry, Aug-15, Volume: 19, Issue:16
| Inhibition studies of the β-carbonic anhydrases from the bacterial pathogen Salmonella enterica serovar Typhimurium with sulfonamides and sulfamates. |
| AID238276 | Ki value against human carbonic anhydrase I (hCA I) | 2005 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 15, Issue:4
| Carbonic anhydrase inhibitors. Inhibition of the transmembrane isozyme XII with sulfonamides-a new target for the design of antitumor and antiglaucoma drugs? |
| AID47932 | Inhibitory activity against human carbonic anhydrase II (CA2) | 2000 | Journal of medicinal chemistry, Jan-27, Volume: 43, Issue:2
| Carbonic anhydrase inhibitors: synthesis of membrane-impermeant low molecular weight sulfonamides possessing in vivo selectivity for the membrane-bound versus cytosolic isozymes. |
| AID577526 | Inhibition of human carbonic anhydrase I by spectrophotometry at pH 7.5 | 2011 | Bioorganic & medicinal chemistry, Feb-01, Volume: 19, Issue:3
| A new β-carbonic anhydrase from Brucella suis, its cloning, characterization, and inhibition with sulfonamides and sulfamates, leading to impaired pathogen growth. |
| AID369272 | Inhibition of human recombinant carbonic anhydrase 2 by stopped flow CO2 hydrase assay | 2009 | Journal of medicinal chemistry, Feb-12, Volume: 52, Issue:3
| Cloning, expression, post-translational modifications and inhibition studies on the latest mammalian carbonic anhydrase isoform, CA XV. |
| AID50371 | Inhibitory activity against human cloned carbonic anhydrase isozyme I by esterase assay method. | 2003 | Bioorganic & medicinal chemistry letters, Mar-24, Volume: 13, Issue:6
| Carbonic anhydrase inhibitors: inhibition of the tumor-associated isozyme IX with aromatic and heterocyclic sulfonamides. |
| AID263639 | Selectivity for Helicobacter pylori recombinant CA over human recombinant CA2 | 2006 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 16, Issue:8
| Carbonic anhydrase inhibitors: cloning and sulfonamide inhibition studies of a carboxyterminal truncated alpha-carbonic anhydrase from Helicobacter pylori. |
| AID644380 | Inhibition of human recombinant carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration assay | 2012 | Bioorganic & medicinal chemistry, Feb-15, Volume: 20, Issue:4
| Cloning, characterization and sulfonamide inhibition studies of an α-carbonic anhydrase from the living fossil sponge Astrosclera willeyana. |
| AID222127 | Inhibition of cloned isozyme, human carbonic anhydrase IV | 2001 | Bioorganic & medicinal chemistry letters, Feb-26, Volume: 11, Issue:4
| Carbonic anhydrase inhibitors: synthesis of sulfonamides incorporating dtpa tails and of their zinc complexes with powerful topical antiglaucoma properties. |
| AID50367 | Inhibitory activity against human carbonic anhydrase I (CA1) | 2000 | Journal of medicinal chemistry, Jan-27, Volume: 43, Issue:2
| Carbonic anhydrase inhibitors: synthesis of membrane-impermeant low molecular weight sulfonamides possessing in vivo selectivity for the membrane-bound versus cytosolic isozymes. |
| AID50353 | Inhibitory activity against Human carbonic anhydrase I | 2002 | Journal of medicinal chemistry, Mar-28, Volume: 45, Issue:7
| Carbonic anhydrase inhibitors. A general approach for the preparation of water-soluble sulfonamides incorporating polyamino-polycarboxylate tails and of their metal complexes possessing long-lasting, topical intraocular pressure-lowering properties. |
| AID243011 | Selectivity ratio against human carbonic anhydrases II and XII | 2005 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 15, Issue:4
| Carbonic anhydrase inhibitors. Inhibition of the transmembrane isozyme XII with sulfonamides-a new target for the design of antitumor and antiglaucoma drugs? |
| AID275809 | Inhibition of catalytic domain of human recombinant CA IX | 2007 | Journal of medicinal chemistry, Jan-25, Volume: 50, Issue:2
| Carbonic anhydrase inhibitors. DNA cloning, characterization, and inhibition studies of the human secretory isoform VI, a new target for sulfonamide and sulfamate inhibitors. |
| AID1796582 | CA Inhibition Assay from Article 10.1021/jm050483n: \\Carbonic anhydrase inhibitors. The mitochondrial isozyme VB as a new target for sulfonamide and sulfamate inhibitors.\\ | 2005 | Journal of medicinal chemistry, Dec-01, Volume: 48, Issue:24
| Carbonic anhydrase inhibitors. The mitochondrial isozyme VB as a new target for sulfonamide and sulfamate inhibitors. |
| AID1796552 | CA Inhibition Assay from Article 10.1021/jm0512600: \\Carbonic anhydrase inhibitors: DNA cloning and inhibition studies of the alpha-carbonic anhydrase from Helicobacter pylori, a new target for developing sulfonamide and sulfamate gastric drugs.\\ | 2006 | Journal of medicinal chemistry, Mar-23, Volume: 49, Issue:6
| Carbonic anhydrase inhibitors: DNA cloning and inhibition studies of the alpha-carbonic anhydrase from Helicobacter pylori, a new target for developing sulfonamide and sulfamate gastric drugs. |
| AID1798769 | CA Inhibition Assay from Article 10.1021/jm801267c: \\Cloning, expression, post-translational modifications and inhibition studies on the latest mammalian carbonic anhydrase isoform, CA XV.\\ | 2009 | Journal of medicinal chemistry, Feb-12, Volume: 52, Issue:3
| Cloning, expression, post-translational modifications and inhibition studies on the latest mammalian carbonic anhydrase isoform, CA XV. |
| AID977610 | Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB | 2012 | Bioorganic & medicinal chemistry, Feb-15, Volume: 20, Issue:4
| Cloning, characterization and sulfonamide inhibition studies of an α-carbonic anhydrase from the living fossil sponge Astrosclera willeyana. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |