| Assay ID | Title | Year | Journal | Article |
|---|
| AID1296008 | Cytotoxic Profiling of Annotated Libraries Using Quantitative High-Throughput Screening | 2020 | SLAS discovery : advancing life sciences R & D, 01, Volume: 25, Issue:1
| Cytotoxic Profiling of Annotated and Diverse Chemical Libraries Using Quantitative High-Throughput Screening. |
| AID1347157 | Confirmatory screen GU Rhodamine qHTS for Zika virus inhibitors qHTS | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1347161 | Confirmatory screen NINDS Rhodamine qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1347160 | Primary screen NINDS Rhodamine qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1346986 | P-glycoprotein substrates identified in KB-3-1 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5
| A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
| AID1347169 | Tertiary RLuc qRT-PCR qHTS assay for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1346987 | P-glycoprotein substrates identified in KB-8-5-11 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5
| A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
| AID1347159 | Primary screen GU Rhodamine qHTS for Zika virus inhibitors: Unlinked NS2B-NS3 protease assay | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID329457 | Activation of ERG1 in guinea pig myocytes assessed as Increase in rapid delayed rectifier potassium tail currents at 10 uM at -50 mV by voltage clamp technique | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Aug-21, Volume: 104, Issue:34
| Structural basis of action for a human ether-a-go-go-related gene 1 potassium channel activator. |
| AID329478 | Activation of human ERG1 L550A mutant expressed in Xenopus laevis oocytes assessed as shifting of voltage dependence of inactivation towards positive potentials at 3 uM by two electrode voltage clamp technique | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Aug-21, Volume: 104, Issue:34
| Structural basis of action for a human ether-a-go-go-related gene 1 potassium channel activator. |
| AID329472 | Activation of human ERG1 N658A mutant expressed in Xenopus laevis oocytes assessed as slowing of tail current deactivation at 3 uM by two electrode voltage clamp technique | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Aug-21, Volume: 104, Issue:34
| Structural basis of action for a human ether-a-go-go-related gene 1 potassium channel activator. |
| AID329491 | Activation of human ERG1 Y652A mutant expressed in Xenopus laevis oocytes assessed as shifting of voltage dependence of inactivation towards positive potentials at 3 uM by two electrode voltage clamp technique | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Aug-21, Volume: 104, Issue:34
| Structural basis of action for a human ether-a-go-go-related gene 1 potassium channel activator. |
| AID329469 | Activation of human ERG1 V659A mutant expressed in Xenopus laevis oocytes assessed as slowing of tail current deactivation at 3 uM by two electrode voltage clamp technique | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Aug-21, Volume: 104, Issue:34
| Structural basis of action for a human ether-a-go-go-related gene 1 potassium channel activator. |
| AID329468 | Activation of human ERG1 N658A mutant expressed in Xenopus laevis oocytes assessed as slowing of tail current deactivation at 3 uM by two electrode voltage clamp technique | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Aug-21, Volume: 104, Issue:34
| Structural basis of action for a human ether-a-go-go-related gene 1 potassium channel activator. |
| AID329492 | Effect on human ERG1 S620T/L666A mutant expressed in Xenopus laevis oocytes at 3 uM by two electrode voltage clamp technique | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Aug-21, Volume: 104, Issue:34
| Structural basis of action for a human ether-a-go-go-related gene 1 potassium channel activator. |
| AID329455 | Activation of human ERG1 isoform 1 expressed in Xenopus laevis oocytes assessed as enhancement of current magnitude by two electrode voltage clamp technique | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Aug-21, Volume: 104, Issue:34
| Structural basis of action for a human ether-a-go-go-related gene 1 potassium channel activator. |
| AID329488 | Activation of human ERG1 isoform 1 expressed in Xenopus laevis oocytes assessed as slowing of tail current deactivation by two electrode voltage clamp technique | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Aug-21, Volume: 104, Issue:34
| Structural basis of action for a human ether-a-go-go-related gene 1 potassium channel activator. |
| AID329481 | Inhibition of human ERG1 L666A mutant expressed in Xenopus laevis oocytes assessed as decrease in current amplitude by two electrode voltage clamp technique | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Aug-21, Volume: 104, Issue:34
| Structural basis of action for a human ether-a-go-go-related gene 1 potassium channel activator. |
| AID329487 | Effect on human ERG1 G628C/N588K mutant expressed in Xenopus laevis oocytes assessed as current magnitude at 3 uM by two electrode voltage clamp technique | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Aug-21, Volume: 104, Issue:34
| Structural basis of action for a human ether-a-go-go-related gene 1 potassium channel activator. |
| AID329476 | Activation of human ERG1 Y667A mutant expressed in Xenopus laevis oocytes assessed as shifting of voltage dependence of inactivation towards positive potentials at 3 uM by two electrode voltage clamp technique | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Aug-21, Volume: 104, Issue:34
| Structural basis of action for a human ether-a-go-go-related gene 1 potassium channel activator. |
| AID329474 | Activation of human ERG1 I662A mutant expressed in Xenopus laevis oocytes assessed as shifting of voltage dependence of inactivation towards positive potentials at 3 uM by two electrode voltage clamp technique | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Aug-21, Volume: 104, Issue:34
| Structural basis of action for a human ether-a-go-go-related gene 1 potassium channel activator. |
| AID329479 | Activation of human ERG1 F557L mutant expressed in Xenopus laevis oocytes assessed as shifting of voltage dependence of inactivation towards positive potentials at 30 uM by two electrode voltage clamp technique | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Aug-21, Volume: 104, Issue:34
| Structural basis of action for a human ether-a-go-go-related gene 1 potassium channel activator. |
| AID329486 | Effect on human ERG1 G628C/S631C mutant expressed in Xenopus laevis oocytes at 3 uM by two electrode voltage clamp technique | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Aug-21, Volume: 104, Issue:34
| Structural basis of action for a human ether-a-go-go-related gene 1 potassium channel activator. |
| AID329459 | Activation of human ERG1 isoform 1 expressed in Xenopus laevis oocytes assessed as shifting of voltage dependence of inactivation towards positive potentials at 1 uM by two electrode voltage clamp technique | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Aug-21, Volume: 104, Issue:34
| Structural basis of action for a human ether-a-go-go-related gene 1 potassium channel activator. |
| AID329489 | Activation of human ERG1 isoform 1 expressed in Xenopus laevis oocytes assessed as increase in peak tail current at 30 uM by two electrode voltage clamp technique | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Aug-21, Volume: 104, Issue:34
| Structural basis of action for a human ether-a-go-go-related gene 1 potassium channel activator. |
| AID329460 | Activation of human ERG1 isoform 1 expressed in Xenopus laevis oocytes assessed as shifting of voltage dependence of inactivation towards positive potentials at 3 uM by two electrode voltage clamp technique | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Aug-21, Volume: 104, Issue:34
| Structural basis of action for a human ether-a-go-go-related gene 1 potassium channel activator. |
| AID329475 | Activation of human ERG1 L666A mutant expressed in Xenopus laevis oocytes assessed as shifting of voltage dependence of inactivation towards positive potentials at 3 uM by two electrode voltage clamp technique | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Aug-21, Volume: 104, Issue:34
| Structural basis of action for a human ether-a-go-go-related gene 1 potassium channel activator. |
| AID329485 | Effect on human ERG1 S631A/L666A mutant expressed in Xenopus laevis oocytes at 3 uM by two electrode voltage clamp technique | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Aug-21, Volume: 104, Issue:34
| Structural basis of action for a human ether-a-go-go-related gene 1 potassium channel activator. |
| AID329471 | Activation of human ERG1 F557L mutant expressed in Xenopus laevis oocytes assessed as slowing of tail current deactivation at 3 uM by two electrode voltage clamp technique | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Aug-21, Volume: 104, Issue:34
| Structural basis of action for a human ether-a-go-go-related gene 1 potassium channel activator. |
| AID329467 | Activation of human ERG1 F557L mutant expressed in Xenopus laevis oocytes assessed as slowing of tail current deactivation at 3 uM by two electrode voltage clamp technique | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Aug-21, Volume: 104, Issue:34
| Structural basis of action for a human ether-a-go-go-related gene 1 potassium channel activator. |
| AID329456 | Activation of human ERG1 expressed in CHO cells assessed as enhancement of current magnitude at 10 uM by two electrode voltage clamp technique | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Aug-21, Volume: 104, Issue:34
| Structural basis of action for a human ether-a-go-go-related gene 1 potassium channel activator. |
| AID329461 | Activation of human ERG1 isoform 1 expressed in Xenopus laevis oocytes assessed as shifting of voltage dependence of inactivation towards positive potentials at 10 uM by two electrode voltage clamp technique | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Aug-21, Volume: 104, Issue:34
| Structural basis of action for a human ether-a-go-go-related gene 1 potassium channel activator. |
| AID329482 | Activation of human ERG1 S631A mutant expressed in Xenopus laevis oocytes assessed as slowing of tail current deactivation at 3 uM by two electrode voltage clamp technique | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Aug-21, Volume: 104, Issue:34
| Structural basis of action for a human ether-a-go-go-related gene 1 potassium channel activator. |
| AID329465 | Binding affinity to human ERG1 expressed in Xenopus laevis oocytes assessed as half-saturation concentration | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Aug-21, Volume: 104, Issue:34
| Structural basis of action for a human ether-a-go-go-related gene 1 potassium channel activator. |
| AID329464 | Activation of human ERG1 isoform 1 expressed in Xenopus laevis oocytes assessed as increase in peak tail current magnitude by two electrode voltage clamp technique | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Aug-21, Volume: 104, Issue:34
| Structural basis of action for a human ether-a-go-go-related gene 1 potassium channel activator. |
| AID329477 | Activation of human ERG1 V549A mutant expressed in Xenopus laevis oocytes assessed as shifting of voltage dependence of inactivation towards positive potentials at 3 uM by two electrode voltage clamp technique | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Aug-21, Volume: 104, Issue:34
| Structural basis of action for a human ether-a-go-go-related gene 1 potassium channel activator. |
| AID329480 | Activation of human ERG1 L666A mutant expressed in Xenopus laevis oocytes assessed as shifting of voltage dependence of inactivation towards positive potentials at 30 uM by two electrode voltage clamp technique | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Aug-21, Volume: 104, Issue:34
| Structural basis of action for a human ether-a-go-go-related gene 1 potassium channel activator. |
| AID329484 | Activation of human ERG1 L666A mutant expressed in Xenopus laevis oocytes assessed as slowing of tail current deactivation at 3 uM by two electrode voltage clamp technique | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Aug-21, Volume: 104, Issue:34
| Structural basis of action for a human ether-a-go-go-related gene 1 potassium channel activator. |
| AID329466 | Activation of human ERG1 L553A mutant expressed in Xenopus laevis oocytes assessed as slowing of tail current deactivation at 3 uM by two electrode voltage clamp technique | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Aug-21, Volume: 104, Issue:34
| Structural basis of action for a human ether-a-go-go-related gene 1 potassium channel activator. |
| AID329458 | Activation of ERG1 in guinea pig myocytes assessed as increase in rapid delayed rectifier potassium tail currents at 30 uM at -50 mV by voltage clamp technique | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Aug-21, Volume: 104, Issue:34
| Structural basis of action for a human ether-a-go-go-related gene 1 potassium channel activator. |
| AID329463 | Activation of human ERG1 isoform 1 expressed in Xenopus laevis oocytes assessed as shifting of voltage dependence of inactivation towards positive potentials by two electrode voltage clamp technique | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Aug-21, Volume: 104, Issue:34
| Structural basis of action for a human ether-a-go-go-related gene 1 potassium channel activator. |
| AID329483 | Activation of human ERG1 S631A mutant expressed in Xenopus laevis oocytes assessed as enhancement of current magnitude at 3 uM by two electrode voltage clamp technique | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Aug-21, Volume: 104, Issue:34
| Structural basis of action for a human ether-a-go-go-related gene 1 potassium channel activator. |
| AID329462 | Activation of human ERG1 isoform 1 expressed in Xenopus laevis oocytes assessed as shifting of voltage dependence of inactivation towards positive potentials at 30 uM by two electrode voltage clamp technique | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Aug-21, Volume: 104, Issue:34
| Structural basis of action for a human ether-a-go-go-related gene 1 potassium channel activator. |
| AID329490 | Activation of human ERG1 Y652A mutant expressed in Xenopus laevis oocytes assessed as slowing of tail current deactivation at 3 uM by two electrode voltage clamp technique | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Aug-21, Volume: 104, Issue:34
| Structural basis of action for a human ether-a-go-go-related gene 1 potassium channel activator. |
| AID329473 | Activation of human ERG1 V659A mutant expressed in Xenopus laevis oocytes assessed as slowing of tail current deactivation at 3 uM by two electrode voltage clamp technique | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Aug-21, Volume: 104, Issue:34
| Structural basis of action for a human ether-a-go-go-related gene 1 potassium channel activator. |
| AID329470 | Activation of human ERG1 L553A mutant expressed in Xenopus laevis oocytes assessed as slowing of tail current deactivation at 3 uM by two electrode voltage clamp technique | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Aug-21, Volume: 104, Issue:34
| Structural basis of action for a human ether-a-go-go-related gene 1 potassium channel activator. |
| AID1346751 | Human Kv11.1 (Voltage-gated potassium channels) | 2005 | Molecular pharmacology, Mar, Volume: 67, Issue:3
| Discovery of a small molecule activator of the human ether-a-go-go-related gene (HERG) cardiac K+ channel. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |