| Assay ID | Title | Year | Journal | Article |
|---|
| AID638412 | Anticancer activity against human HT-29 cells assessed as growth inhibition at 50 uM after 48 hrs by SRB assay | 2012 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 22, Issue:1
| Acyl derivatives of boswellic acids as inhibitors of NF-κB and STATs. |
| AID1194658 | Inhibition of VEGFR-2 (unknown origin) at 50 uM after 1 hr by luminescence assay | 2015 | Bioorganic & medicinal chemistry, May-01, Volume: 23, Issue:9
| Synthesis and structure-activity relationships of boswellic acid derivatives as potent VEGFR-2 inhibitors. |
| AID1617779 | Inhibition of ovine recombinant COX1 assessed as residual activity at 42 uM using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition measured after 45 mins by LC-MS analysis | 2019 | Journal of natural products, 12-27, Volume: 82, Issue:12
| Structure-Activity Relationships of Pentacyclic Triterpenoids as Inhibitors of Cyclooxygenase and Lipoxygenase Enzymes. |
| AID638416 | Anticancer activity against human DU145 cells assessed as growth inhibition at 50 uM after 48 hrs by SRB assay | 2012 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 22, Issue:1
| Acyl derivatives of boswellic acids as inhibitors of NF-κB and STATs. |
| AID303272 | Cytotoxicity against human 502713 cells at 10 uM after 48 hrs | 2007 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 17, Issue:23
| Cytotoxic and apoptotic activities of novel amino analogues of boswellic acids. |
| AID638414 | Anticancer activity against human COLO205 cells assessed as growth inhibition at 50 uM after 48 hrs by SRB assay | 2012 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 22, Issue:1
| Acyl derivatives of boswellic acids as inhibitors of NF-κB and STATs. |
| AID1153839 | Inhibition of microsomal PGES1 isolated from IL-1beta-stimulated human A549 cells preincubated for 15 mins followed by substrate addition measured after 1 min by RP-HPLC analysis | 2014 | Journal of natural products, Jun-27, Volume: 77, Issue:6
| Tetra- and pentacyclic triterpene acids from the ancient anti-inflammatory remedy frankincense as inhibitors of microsomal prostaglandin E(2) synthase-1. |
| AID638413 | Anticancer activity against human SW620 cells assessed as growth inhibition at 50 uM after 48 hrs by SRB assay | 2012 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 22, Issue:1
| Acyl derivatives of boswellic acids as inhibitors of NF-κB and STATs. |
| AID1617775 | Inhibition of human recombinant 5-LOX expressed in insect cells assessed residual activity using arachidonic acid at 42 uM as substrate preincubated for 5 mins followed by substrate addition measured after 20 mins in dark by ferric ion oxidation-xylenol o | 2019 | Journal of natural products, 12-27, Volume: 82, Issue:12
| Structure-Activity Relationships of Pentacyclic Triterpenoids as Inhibitors of Cyclooxygenase and Lipoxygenase Enzymes. |
| AID1617780 | Inhibition of human recombinant COX2 expressed in baculovirus infected sf21 cells assessed as decrease in PGE2 formation using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition measured after 45 mins by LC-MS analysis | 2019 | Journal of natural products, 12-27, Volume: 82, Issue:12
| Structure-Activity Relationships of Pentacyclic Triterpenoids as Inhibitors of Cyclooxygenase and Lipoxygenase Enzymes. |
| AID1617777 | Inhibition of human recombinant N-terminal His-tagged 15-LOX2 expressed in Escherichia coli assessed as residual activity at 42 uM using arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 20 mins in dark by | 2019 | Journal of natural products, 12-27, Volume: 82, Issue:12
| Structure-Activity Relationships of Pentacyclic Triterpenoids as Inhibitors of Cyclooxygenase and Lipoxygenase Enzymes. |
| AID590119 | Cytotoxicity against human HL60 cells after 48 hrs by MTT assay | 2011 | European journal of medicinal chemistry, Apr, Volume: 46, Issue:4
| A comparative study of proapoptotic potential of cyano analogues of boswellic acid and 11-keto-boswellic acid. |
| AID638417 | Anticancer activity against human PC3 cells assessed as growth inhibition at 50 uM after 48 hrs by SRB assay | 2012 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 22, Issue:1
| Acyl derivatives of boswellic acids as inhibitors of NF-κB and STATs. |
| AID691830 | Plasma concentration in rat at 240 mg/kg, po administered using compound, Lipoid S100 and pluronic f127 ratio 1:1:1 formulation relative to non-formulated compound after 4 to 6 hrs | 2012 | Journal of natural products, Oct-26, Volume: 75, Issue:10
| Effect of phospholipid-based formulations of Boswellia serrata extract on the solubility, permeability, and absorption of the individual boswellic acid constituents present. |
| AID303270 | Cytotoxicity against human DU145 cells at 10 uM after 48 hrs | 2007 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 17, Issue:23
| Cytotoxic and apoptotic activities of novel amino analogues of boswellic acids. |
| AID303273 | Cytotoxicity against human HT29 cells at 10 uM after 48 hrs | 2007 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 17, Issue:23
| Cytotoxic and apoptotic activities of novel amino analogues of boswellic acids. |
| AID1272076 | Anti-inflammatory activity in human PBMC assessed as inhibition of LPS-induced TNFalpha expression at 10 uM after 5 hrs | 2016 | Bioorganic & medicinal chemistry letters, Jan-15, Volume: 26, Issue:2
| Analogues of boswellic acids as inhibitors of pro-inflammatory cytokines TNF-α and IL-6. |
| AID303269 | Cytotoxicity against human MCF7 cells at 10 uM after 48 hrs | 2007 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 17, Issue:23
| Cytotoxic and apoptotic activities of novel amino analogues of boswellic acids. |
| AID1617776 | Inhibition of human recombinant N-terminal His-tagged 15-LOX2 expressed in Escherichia coli using arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 20 mins in dark by ferric ion oxidation-xylenol orange as | 2019 | Journal of natural products, 12-27, Volume: 82, Issue:12
| Structure-Activity Relationships of Pentacyclic Triterpenoids as Inhibitors of Cyclooxygenase and Lipoxygenase Enzymes. |
| AID303271 | Cytotoxicity against human SW620 cells at 10 uM after 48 hrs | 2007 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 17, Issue:23
| Cytotoxic and apoptotic activities of novel amino analogues of boswellic acids. |
| AID1617781 | Inhibition of human recombinant COX2 expressed in baculovirus infected sf21 cells assessed as residual activity at 42 uM using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition measured after 45 mins by LC-MS analysis r | 2019 | Journal of natural products, 12-27, Volume: 82, Issue:12
| Structure-Activity Relationships of Pentacyclic Triterpenoids as Inhibitors of Cyclooxygenase and Lipoxygenase Enzymes. |
| AID691785 | Drug level in rat brain at 240 mg/kg, po administered using compound, Lipoid S100 and pluronic f127 ratio 1:1:1 formulation | 2012 | Journal of natural products, Oct-26, Volume: 75, Issue:10
| Effect of phospholipid-based formulations of Boswellia serrata extract on the solubility, permeability, and absorption of the individual boswellic acid constituents present. |
| AID638415 | Anticancer activity against human Hep2 cells assessed as growth inhibition at 50 uM after 48 hrs by SRB assay | 2012 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 22, Issue:1
| Acyl derivatives of boswellic acids as inhibitors of NF-κB and STATs. |
| AID1357408 | Inhibition of mPGES1 in human A549 cell microsomal membrane using pGH2 as substrate pretreated for 15 mins followed by substrate addition and measured after 1 min by RP-HPLC method | 2018 | European journal of medicinal chemistry, Jun-10, Volume: 153 | Plant-derived mPGES-1 inhibitors or suppressors: A new emerging trend in the search for small molecules to combat inflammation. |
| AID590124 | Cytotoxicity against human HeLa cells after 48 hrs by MTT assay | 2011 | European journal of medicinal chemistry, Apr, Volume: 46, Issue:4
| A comparative study of proapoptotic potential of cyano analogues of boswellic acid and 11-keto-boswellic acid. |
| AID1617778 | Inhibition of ovine recombinant COX1 assessed as decrease in formation of PGE2 using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition measured after 45 mins by LC-MS analysis | 2019 | Journal of natural products, 12-27, Volume: 82, Issue:12
| Structure-Activity Relationships of Pentacyclic Triterpenoids as Inhibitors of Cyclooxygenase and Lipoxygenase Enzymes. |
| AID1617774 | Inhibition of human recombinant 5-LOX expressed in insect cells assessed as decrease in production of 5-HPETE and 5-HETE using arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 20 mins in dark by ferric io | 2019 | Journal of natural products, 12-27, Volume: 82, Issue:12
| Structure-Activity Relationships of Pentacyclic Triterpenoids as Inhibitors of Cyclooxygenase and Lipoxygenase Enzymes. |
| AID1194657 | Antiproliferation activity against HUVEC cells after 48 hrs by CCK-8 assay | 2015 | Bioorganic & medicinal chemistry, May-01, Volume: 23, Issue:9
| Synthesis and structure-activity relationships of boswellic acid derivatives as potent VEGFR-2 inhibitors. |
| AID691784 | Drug level in rat brain at 240 mg/kg, po | 2012 | Journal of natural products, Oct-26, Volume: 75, Issue:10
| Effect of phospholipid-based formulations of Boswellia serrata extract on the solubility, permeability, and absorption of the individual boswellic acid constituents present. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |