| Substance | Relationship Strength | Studies | Trials | Classes | Roles |
|---|
acetone
methyl ketone : A ketone of formula RC(=O)CH3 (R =/= H). | 2.01 | 1 | 0 | ketone body;
methyl ketone;
propanones;
volatile organic compound | EC 3.5.1.4 (amidase) inhibitor;
human metabolite;
polar aprotic solvent |
4-aminophenol
4-aminophenol: RN given refers to parent cpd. 4-aminophenol : An amino phenol (one of the three possible isomers) which has the single amino substituent located para to the phenolic -OH group. | 2.15 | 1 | 0 | aminophenol | allergen;
metabolite |
phosphoglycolate
phosphoglycolate: RN given refers to parent acid. 2-phosphoglycolic acid : The O-phospho derivative of glycolic acid. | 2.01 | 1 | 0 | carboxyalkyl phosphate | Escherichia coli metabolite;
mouse metabolite |
alpha-glycerophosphoric acid
[no description available] | 2.01 | 1 | 0 | glycerol monophosphate | algal metabolite;
human metabolite |
histamine
[no description available] | 2.11 | 1 | 0 | aralkylamino compound;
imidazoles | human metabolite;
mouse metabolite;
neurotransmitter |
thiocyanic acid
thiocyanic acid : A hydracid that is cyanic acid in which the oxygen is replaced by a sulfur atom. | 2.01 | 1 | 0 | hydracid;
one-carbon compound;
organosulfur compound | Escherichia coli metabolite |
nickel
Nickel: A trace element with the atomic symbol Ni, atomic number 28, and atomic weight 58.69. It is a cofactor of the enzyme UREASE.. nickel ion : A nickel atom having a net electric charge.. nickel atom : Chemical element (nickel group element atom) with atomic number 28. | 2.08 | 1 | 0 | metal allergen;
nickel group element atom | epitope;
micronutrient |
palmitic acid
Palmitic Acid: A common saturated fatty acid found in fats and waxes including olive oil, palm oil, and body lipids.. hexadecanoic acid : A straight-chain, sixteen-carbon, saturated long-chain fatty acid. | 2.41 | 2 | 0 | long-chain fatty acid;
straight-chain saturated fatty acid | algal metabolite;
Daphnia magna metabolite;
EC 1.1.1.189 (prostaglandin-E2 9-reductase) inhibitor;
plant metabolite |
phenethylamine
phenethylamine: RN given refers to parent cpd; structure in Merck Index, 9th ed, #7016. 2-phenylethylamine : A phenylethylamine having the phenyl substituent at the 2-position. | 3.12 | 5 | 0 | alkaloid;
aralkylamine;
phenylethylamine | Escherichia coli metabolite;
human metabolite;
mouse metabolite |
aminopropionitrile
Aminopropionitrile: Reagent used as an intermediate in the manufacture of beta-alanine and pantothenic acid. | 2.15 | 1 | 0 | aminopropionitrile | antineoplastic agent;
antirheumatic drug;
collagen cross-linking inhibitor;
plant metabolite |
benzamidine
benzamidine: RN given refers to parent cpd. benzamidine : A carboxamidine that is benzene carrying an amidino group. | 2.41 | 2 | 0 | benzenes;
carboxamidine | serine protease inhibitor |
nordazepam
Nordazepam: An intermediate in the metabolism of DIAZEPAM to OXAZEPAM. It may have actions similar to those of diazepam.. nordazepam : A 1,4-benzodiazepinone having phenyl and chloro substituents at positions 5 and 7 respectively; it has anticonvulsant, anxiolytic, muscle relaxant and sedative properties but is used primarily in the treatment of anxiety. | 1.96 | 1 | 0 | 1,4-benzodiazepinone;
organochlorine compound | anticonvulsant;
anxiolytic drug;
GABA modulator;
human metabolite;
sedative |
diazepam
Diazepam: A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.. diazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a methyl group at position 1 and a phenyl group at position 5. | 1.96 | 1 | 0 | 1,4-benzodiazepinone;
organochlorine compound | anticonvulsant;
anxiolytic drug;
environmental contaminant;
sedative;
xenobiotic |
fludiazepam
fludiazepam: RN given refers to parent cpd; structure | 1.96 | 1 | 0 | 1,4-benzodiazepinone;
organochlorine compound;
organofluorine compound | anxiolytic drug |
flunitrazepam
Flunitrazepam: A benzodiazepine with pharmacologic actions similar to those of DIAZEPAM that can cause ANTEROGRADE AMNESIA. Some reports indicate that it is used as a date rape drug and suggest that it may precipitate violent behavior. The United States Government has banned the importation of this drug.. flunitrazepam : A 1,4-benzodiazepinone that is nitrazepam substituted by a methyl group at position 1 and by a fluoro group at position 2'. It is a potent hypnotic, sedative, and amnestic drug used to treat chronic insomnia. | 1.96 | 1 | 0 | 1,4-benzodiazepinone;
C-nitro compound;
monofluorobenzenes | anxiolytic drug;
GABAA receptor agonist;
sedative |
indolepropanol phosphate
indolepropanol phosphate: binds specifically to the alpha subunit, but not to the beta subunit of tryptophan synthase. 3-(indol-3-yl)propyl phosphate : An monoalkyl phosphate compound having an O-3-(indol-3-yl)propyl substituent. | 2.01 | 1 | 0 | indoles;
monoalkyl phosphate | |
isoniazid
Hydra: A genus of freshwater polyps in the family Hydridae, order Hydroida, class HYDROZOA. They are of special interest because of their complex organization and because their adult organization corresponds roughly to the gastrula of higher animals.. hydrazide : Compounds derived from oxoacids RkE(=O)l(OH)m (l =/= 0) by replacing -OH by -NRNR2 (R groups are commonly H). (IUPAC). | 2.11 | 1 | 0 | carbohydrazide | antitubercular agent;
drug allergen |
nimetazepam
nimetazepam : A nitrazepam which is substituted at positions 1 by a methyl group. It is used as an anticonvulsant and as a hypnotic for the short-term management of insomnia. | 1.96 | 1 | 0 | 1,4-benzodiazepinone;
C-nitro compound | anticonvulsant;
antispasmodic drug;
GABA modulator;
sedative |
nitrazepam
Nitrazepam: A benzodiazepine derivative used as an anticonvulsant and hypnotic.. nitrazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one which is substituted at positions 5 and 7 by phenyl and nitro groups, respectively. It is used as a hypnotic for the short-term management of insomnia and for the treatment of epileptic spasms in infants (West's syndrome). | 1.96 | 1 | 0 | 1,4-benzodiazepinone;
C-nitro compound | anticonvulsant;
antispasmodic drug;
drug metabolite;
GABA modulator;
sedative |
stearic acid
octadecanoic acid : A C18 straight-chain saturated fatty acid component of many animal and vegetable lipids. As well as in the diet, it is used in hardening soaps, softening plastics and in making cosmetics, candles and plastics. | 2.01 | 1 | 0 | long-chain fatty acid;
saturated fatty acid;
straight-chain saturated fatty acid | algal metabolite;
Daphnia magna metabolite;
human metabolite;
plant metabolite |
histidine
Histidine: An essential amino acid that is required for the production of HISTAMINE.. L-histidine : The L-enantiomer of the amino acid histidine.. histidine : An alpha-amino acid that is propanoic acid bearing an amino substituent at position 2 and a 1H-imidazol-4-yl group at position 3. | 2.01 | 1 | 0 | amino acid zwitterion;
histidine;
L-alpha-amino acid;
polar amino acid zwitterion;
proteinogenic amino acid | algal metabolite;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
Saccharomyces cerevisiae metabolite |
1-nitronaphthalene
1-nitronaphthalene: RN given refers to cpd with locant for nitro moiety in 1 position. 1-nitronaphthalene : A mononitronaphthalene substituted by a nitro group at position 1.. mononitronaphthalene : A nitronaphthalene carrying a single nitro group at unspecified position.. nitronaphthalene : A nitroarene that is naphthalene substituted by at least one nitro group. | 2.15 | 1 | 0 | mononitronaphthalene | environmental contaminant;
mouse metabolite |
xylitol
xylooligosaccharide: structure in first source. pentitol : An alditol obtained by reduction of any pentose.. xylooligosaccharide : An oligosaccharide comprised of xylose residues. | 2.01 | 1 | 0 | | |
1,2,3,4-tetrahydroisoquinoline
1,2,3,4-tetrahydroisoquinoline: RN given refers to cpd with locants as specified | 1.97 | 1 | 0 | isoquinolines | |
benzylamine
aminotoluene : Any member of the class of toluenes carrying one or more amino groups. | 2.91 | 4 | 0 | aralkylamine;
primary amine | allergen;
EC 3.5.5.1 (nitrilase) inhibitor;
plant metabolite |
phenylhydrazine
[no description available] | 2.15 | 1 | 0 | phenylhydrazines | xenobiotic |
4-chloroaniline
4-chloroaniline: RN given refers to parent cpd; structure. 4-chloroaniline : A chloroaniline in which the chloro atom is para to the aniline amino group. | 2.15 | 1 | 0 | chloroaniline;
monochlorobenzenes | |
dimethoxyphenylethylamine
Dimethoxyphenylethylamine: A derivative of phenethylamine containing two substituent methoxy groups in the phenyl ring.. 3,4-dimethoxyphenylethylamine : An aromatic ether that is the derivative of 2-phenylethylamine with methoxy substituents at the 3- and 4-positions. It is an alkaloid isolated from the Cactaceae family. | 2.03 | 1 | 0 | alkaloid;
aromatic ether;
phenylethylamine | allergen;
plant metabolite |
1-naphthylamine
1-Naphthylamine: A suspected industrial carcinogen (and listed as such by OSHA). Its N-hydroxy metabolite is strongly carcinogenic and mutagenic.. naphthylamine : A primary arylamine that is naphthalene substituted by an amino group at unspecified position.. 1-naphthylamine : A naphthylamine that is naphthalene substituted by an amino group at position 1. | 2.15 | 1 | 0 | naphthylamine | human xenobiotic metabolite |
4-fluoroaniline
4-fluoroaniline: chemical intermediate manufactured by the Halex process; RN given refers to parent cpd; structure given in first source. 4-fluoroaniline : A primary arylamine that is the derivative of aniline in which the hydrogen at position 4 has been substituted by fluorine. It is used as an intermediate in the manufacture of pharmaceuticals, herbicides and plant growth regulators. | 2.15 | 1 | 0 | fluoroaniline;
primary arylamine | |
alpha-aminopyridine
alpha-aminopyridine: RN given refers to parent cpd; structure in Merck Index, 9th ed, #485. aminopyridine : Compounds containing a pyridine skeleton substituted by one or more amine groups. | 2.6 | 1 | 0 | | |
1,3-xylenediamine
1,3-xylenediamine: structure given in first source | 2.03 | 1 | 0 | | |
3-phenylpropylamine
3-phenylpropylamine : A phenylalkylamine that is benzene in which one of the hydrogens is substituted by a 3-aminopropyl group. | 2.92 | 4 | 0 | benzenes;
phenylalkylamine;
primary amino compound | |
nickel chloride
nickel chloride: RN given refers to cpd with MF of Ni-Cl2. nickel dichloride : A compound of nickel and chloride in which the ratio of nickel (in the +2 oxidation state) to chloride is 1:2. | 2.08 | 1 | 0 | nickel coordination entity | calcium channel blocker;
hapten |
(1S,2R)-tranylcypromine
(1S,2R)-tranylcypromine : A 2-phenylcyclopropan-1-amine that is the (1S,2R)-enantiomer of tranylcypromine. | 1.98 | 1 | 0 | 2-phenylcyclopropan-1-amine | |
4-nitrobenzylamine
4-nitrobenzylamine: RN given refers to parent cpd | 2.15 | 1 | 0 | | |
1-deoxynojirimycin
1-deoxy-nojirimycin: structure in first source. duvoglustat : An optically active form of 2-(hydroxymethyl)piperidine-3,4,5-triol having 2R,3R,4R,5S-configuration. | 2.01 | 1 | 0 | 2-(hydroxymethyl)piperidine-3,4,5-triol;
piperidine alkaloid | anti-HIV agent;
anti-obesity agent;
bacterial metabolite;
EC 3.2.1.20 (alpha-glucosidase) inhibitor;
hepatoprotective agent;
hypoglycemic agent;
plant metabolite |
2-aminotetralin
2-aminotetralin: RN given refers to parent cpd without isomeric designation; structure | 1.97 | 1 | 0 | tetralins | |
flupirtine
flupirtine: RN given refers to parent cpd without isomeric designation | 7.6 | 1 | 0 | aminopyridine | |
phenylhydrazine hydrochloride
phenylhydrazine hydrochloride : A hydrochloride resulting from the reaction of equimolar amounts of phenylhydrazine and hydrogen chloride. | 2.15 | 1 | 0 | hydrochloride | |
nitroaniline
nitroaniline: RN given refers to cpd with unspecified locant for nitro moiety. nitroaniline : A substituted aniline that carries one or more nitro groups. | 2.01 | 1 | 0 | | |
abbott 77003
Abbott 77003: a symmetry-based inhibitor of HIV-1 protease | 2.01 | 1 | 0 | | |
amprenavir
[no description available] | 2.01 | 1 | 0 | carbamate ester;
sulfonamide;
tetrahydrofuryl ester | antiviral drug;
HIV protease inhibitor |
2-deoxy-2,3-dehydro-n-acetylneuraminic acid
2-deoxy-2,3-dehydro-N-acetylneuraminic acid: also known as NeuAc2en, but this is also synonym for another compound. 2-deoxy-2,3-dehydro-N-acetylneuraminic acid : N-Acetylneuraminic acid reduced across the 2,3-bond with loss of the hydroxy group at C-2; it is a minor component of body fluids although abundant in sialuria. | 2.01 | 1 | 0 | N-acetylneuraminic acids | |
4-aminomethylbenzoic acid
[no description available] | 2.03 | 1 | 0 | benzoic acids | |
4-methylbenzylamine
[no description available] | 2.67 | 3 | 0 | | |
brinzolamide
brinzolamide: an antiglaucoma agent | 2.01 | 1 | 0 | sulfonamide;
thienothiazine | antiglaucoma drug;
EC 4.2.1.1 (carbonic anhydrase) inhibitor |
4-hydroxyquinoline
4-quinolone : A quinolone that is 1,4-dihydroquinoline substituted by an oxo group at position 4. | 2.15 | 1 | 0 | monohydroxyquinoline;
quinolone | |
4-fluorobenzamide
4-fluorobenzamide: structure in first source | 1.99 | 1 | 0 | | |
a 76889
A 76889: backbone structure gvien in first source | 2.01 | 1 | 0 | | |
methanesulfonamide
[no description available] | 2.01 | 1 | 0 | | |
4-methoxybenzylamine
1-(4-methoxyphenyl)methanamine : An aralkylamino compound that is benzylamine substituted by a methoxy group at the para position. | 2.67 | 3 | 0 | aralkylamino compound;
aromatic ether;
primary amino compound | |
n-desmethylflunitrazepam
[no description available] | 1.96 | 1 | 0 | | |
2-chlorodiazepam
[no description available] | 1.96 | 1 | 0 | | |
4-pyridylmethylamine
4-pyridylmethylamine: structure given in first source | 2.15 | 1 | 0 | | |
4-phenylbutylamine
4-phenylbutylamine: used as a drug partition into lipid bilayers in a cubic liquid-crystalline phase. 4-phenylbutylamine : A phenylalkylamine that is benzene in which one of the hydrogens is substituted by a 4-aminobutyl group. | 2.92 | 4 | 0 | benzenes;
phenylalkylamine;
primary amino compound | |
6-phosphogluconic acid
gluconic acid-6-phosphate: structure. 6-phospho-D-gluconate : A monocarboxylic acid anion resulting from the removal of a proton from the carboxy group of 6-phospho-D-gluconic acid.. 6-phospho-D-gluconic acid : A gluconic acid phosphate having the phosphate group at the 6-position. It is an intermediate in the pentose phosphate pathway. | 2.01 | 1 | 0 | gluconic acid phosphate | fundamental metabolite |
1-methyl-1,2,3,4-tetrahydroisoquinoline
1-methyl-1,2,3,4-tetrahydroisoquinoline: endogenous amine from rat brain | 1.97 | 1 | 0 | isoquinolines | |
1-(1-naphthyl)ethylamine
[no description available] | 2.03 | 1 | 0 | | |
n(alpha)-tosyl-(3-amidinophenyl)alanine piperidide
N(alpha)-(4-toluenesulfonyl)-3-amidinophenylalanylpiperidine: binds to thrombin & trypsin; structure given in first source | 2.01 | 1 | 0 | | |
methotrexate
[no description available] | 2.01 | 1 | 0 | dicarboxylic acid;
monocarboxylic acid amide;
pteridines | abortifacient;
antimetabolite;
antineoplastic agent;
antirheumatic drug;
dermatologic drug;
DNA synthesis inhibitor;
EC 1.5.1.3 (dihydrofolate reductase) inhibitor;
immunosuppressive agent |
n-acetylseryl-leucyl-asparaginyl(phenylalanyl-hydroxyethylamino-prolyl)isoleucyl-valyl methyl ester
N-acetylseryl-leucyl-asparaginyl(phenylalanyl-hydroxyethylamino-prolyl)isoleucyl-valyl methyl ester: inhibitor of HIV Protease; structure given in first source; RN given is for (S-(R*,R*)) isomer | 2.01 | 1 | 0 | | |
n(alpha)-(4-toluenesulfonyl)-4-amidinophenylalanylpiperidine
N(alpha)-(4-toluenesulfonyl)-4-amidinophenylalanylpiperidine: binds to thrombin & trypsin; structure given in first source | 2.01 | 1 | 0 | | |
h 142
H 142: decapeptide inhibitor of human renin; RN given refers to all L-isomer | 2.01 | 1 | 0 | | |
h 256
H 256: heptapeptide inhibitor of pepsin | 2.01 | 1 | 0 | | |
n-valyltryptophan
N-valyltryptophan: RN given refers to (L)-isomer | 2.01 | 1 | 0 | peptide | |
ro 5-3438
Ro 5-3438: structure | 1.96 | 1 | 0 | | |
cp 71362
[no description available] | 2.01 | 1 | 0 | | |
arabinose
[no description available] | 2.01 | 1 | 0 | L-arabinose | Escherichia coli metabolite;
mouse metabolite |
galactose
beta-D-galactose : A D-galactopyranose having beta-configuration at the anomeric centre.. beta-D-galactoside : Any D-galactoside having beta-configuration at its anomeric centre. | 2.01 | 1 | 0 | D-galactopyranose | epitope;
mouse metabolite |
arachidonic acid
icosa-5,8,11,14-tetraenoic acid : Any icosatetraenoic acid with the double bonds at positions 5, 8, 11 and 14.. arachidonate : A long-chain fatty acid anion resulting from the removal of a proton from the carboxy group of arachidonic acid. | 2.01 | 1 | 0 | icosa-5,8,11,14-tetraenoic acid;
long-chain fatty acid;
omega-6 fatty acid | Daphnia galeata metabolite;
EC 3.1.1.1 (carboxylesterase) inhibitor;
human metabolite;
mouse metabolite |
phosphoramidon
phosphoramidon: a membrane metallo-endopeptidase & endothelin-converting enzyme inhibitor; thermolysin inhibitor from culture filtrate of Streptomyces tanashiensis; structure. phosphoramidon : A dipeptide isolated from the cultures of Streptomyces tanashiensis. | 2.01 | 1 | 0 | deoxyaldohexose phosphate;
dipeptide | bacterial metabolite;
EC 3.4.24.11 (neprilysin) inhibitor;
EC 3.4.24.71 (endothelin-converting enzyme 1) inhibitor |
retinol
Vitamin A: Retinol and derivatives of retinol that play an essential role in metabolic functioning of the retina, the growth of and differentiation of epithelial tissue, the growth of bone, reproduction, and the immune response. Dietary vitamin A is derived from a variety of CAROTENOIDS found in plants. It is enriched in the liver, egg yolks, and the fat component of dairy products.. vitamin A : Any member of a group of fat-soluble retinoids produced via metabolism of provitamin A carotenoids that exhibit biological activity against vitamin A deficiency. Vitamin A is involved in immune function, vision, reproduction, and cellular communication.. all-trans-retinol : A retinol in which all four exocyclic double bonds have E- (trans-) geometry.. retinol : A retinoid consisting of 3,7-dimethylnona-2,4,6,8-tetraen-1-ol substituted at position 9 by a 2,6,6-trimethylcyclohex-1-en-1-yl group (geometry of the four exocyclic double bonds is not specified). | 2.01 | 1 | 0 | retinol;
vitamin A | human metabolite;
mouse metabolite;
plant metabolite |
phosphonoacetohydroxamate
phosphonoacetohydroxamic acid : The hydroxamate of phosphonoacetic acid. | 2.01 | 1 | 0 | hydroxamic acid;
organic phosphonate | |
tacrolimus
Tacrolimus: A macrolide isolated from the culture broth of a strain of Streptomyces tsukubaensis that has strong immunosuppressive activity in vivo and prevents the activation of T-lymphocytes in response to antigenic or mitogenic stimulation in vitro.. tacrolimus (anhydrous) : A macrolide lactam containing a 23-membered lactone ring, originally isolated from the fermentation broth of a Japanese soil sample that contained the bacteria Streptomyces tsukubaensis. | 2.01 | 1 | 0 | macrolide lactam | bacterial metabolite;
immunosuppressive agent |
a 76928
A 76928: a diol with C2-symmetry | 2.01 | 1 | 0 | | |
xk 263
[no description available] | 2.01 | 1 | 0 | | |
phenylalanyl-prolyl-arginine
[no description available] | 2.01 | 1 | 0 | oligopeptide | |
sodium perchlorate
sodium perchlorate : An inorganic sodium salt comprising equal numbers of sodium and perchlorate ions. | 2.11 | 1 | 0 | inorganic sodium salt | |
ro 05-4082
ID 690: methyl deriv of clonazepam; structure | 1.96 | 1 | 0 | | |
3-methyl-1,2,3,4-tetrahydroisoquinoline
3-methyl-1,2,3,4-tetrahydroisoquinoline: structure in first source | 1.97 | 1 | 0 | | |
elaidic acid
[no description available] | 2.01 | 1 | 0 | octadec-9-enoic acid | food component |
4-fluorohippuric acid
4-fluorohippuric acid: a urinary metabolite of fluorapacin | 2.6 | 1 | 0 | | |
glycyllysine
glycyllysine: RN given refers to (L)-isomer. Gly-Lys : A dipeptide formed from glycine and L-lysine residues. | 2.01 | 1 | 0 | dipeptide | metabolite |
leucine hydroxamate
leucine hydroxamate: RN given refers to (S)-isomer | 2.01 | 1 | 0 | | |
sodium borohydride
sodium borohydride: RN given refers to parent cpd | 2.05 | 1 | 0 | inorganic sodium salt;
metal tetrahydridoborate | |
pepstatin
pepstatin: inhibits the aspartic protease endothiapepsin | 2.01 | 1 | 0 | pentapeptide;
secondary carboxamide | bacterial metabolite;
EC 3.4.23.* (aspartic endopeptidase) inhibitor |
streptomyces pepsin inhibitor
[no description available] | 2.01 | 1 | 0 | | |
cp 81282
CP 81282: structure given in first source; inhibits human renin and endothiapepsin | 2.01 | 1 | 0 | | |
9-oxo-15-hydroxy-delta 7,10,13-prostatrienoic acid methyl ester
[no description available] | 1.99 | 1 | 0 | | |
lithium perchlorate
lithium perchlorate: stabilizes DNA-polycation complex; RN given refers to parent compound | 2.11 | 1 | 0 | | |
sancycline
sancycline: RN given refers to parent cpd | 1.96 | 1 | 0 | | |
rifampin
Rifampin: A semisynthetic antibiotic produced from Streptomyces mediterranei. It has a broad antibacterial spectrum, including activity against several forms of Mycobacterium. In susceptible organisms it inhibits DNA-dependent RNA polymerase activity by forming a stable complex with the enzyme. It thus suppresses the initiation of RNA synthesis. Rifampin is bactericidal, and acts on both intracellular and extracellular organisms. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p1160) | 2.11 | 1 | 0 | cyclic ketal;
hydrazone;
N-iminopiperazine;
N-methylpiperazine;
rifamycins;
semisynthetic derivative;
zwitterion | angiogenesis inhibitor;
antiamoebic agent;
antineoplastic agent;
antitubercular agent;
DNA synthesis inhibitor;
EC 2.7.7.6 (RNA polymerase) inhibitor;
Escherichia coli metabolite;
geroprotector;
leprostatic drug;
neuroprotective agent;
pregnane X receptor agonist;
protein synthesis inhibitor |