CK-0944666: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
CK-666 : A member of the class of indoles that is 2-methyltryptamine in which a hydrogen attached to the primary amino group has been replaced by a 2-fluorobenzoyl group. It is a cell-permeable inhibitor of actin assembly mediated by actin-related protein Arp2/3 complex which works by binding to Arp2/3 complex, stabilising the inactive state of the complex and preventing its movement into the active conformation. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]
| ID Source | ID |
|---|---|
| PubMed CID | 589075 |
| CHEBI ID | 78843 |
| SCHEMBL ID | 3382638 |
| MeSH ID | M0539345 |
| Synonym |
|---|
| OPREA1_850670 |
| 2-fluoro-n-[2-(2-methyl-1h-indol-3-yl)ethyl]benzamide |
| SCHEMBL3382638 |
| AKOS001725056 |
| STK766770 |
| CKH , |
| ck-666 |
| 442633-00-3 |
| ck 666 |
| ck-0944666 |
| 3UKR |
| CHEBI:78843 |
| ck666 |
| UXRKUKRXVWJFER-UHFFFAOYSA-N , |
| 2-fluoro-n-[2-(2-methyl-1h-indol-3-yl)-ethyl]-benzamide |
| SR-01000536526-1 |
| sr-01000536526 |
| DTXSID70343330 |
| ck-666, >=98% (hplc), powder |
| NCGC00370920-01 |
| Q27147993 |
| 2-fluoro-n-(2-(2-methyl-1h-indol-3-yl)ethyl)benzamide |
| nsc-821559 |
| nsc821559 |
| Z1038843750 |
| CS-0012973 |
| HY-16926 |
| F81773 |
| AS-82972 |
| Role | Description |
|---|---|
| actin polymerisation inhibitor | Any substance that inhibits the polymerisation of the protein actin. |
| [role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] | |
| Class | Description |
|---|---|
| indoles | Any compound containing an indole skeleton. |
| organofluorine compound | An organofluorine compound is a compound containing at least one carbon-fluorine bond. |
| benzamides | |
| [compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] | |
| Protein | Taxonomy | Measurement | Average (µ) | Min (ref.) | Avg (ref.) | Max (ref.) | Bioassay(s) |
|---|---|---|---|---|---|---|---|
| cytochrome P450 family 3 subfamily A polypeptide 4 | Homo sapiens (human) | Potency | 10.6840 | 0.0123 | 7.9835 | 43.2770 | AID1645841 |
| G | Vesicular stomatitis virus | Potency | 21.3174 | 0.0123 | 8.9648 | 39.8107 | AID1645842 |
| cytochrome P450 2D6 | Homo sapiens (human) | Potency | 21.3174 | 0.0010 | 8.3798 | 61.1304 | AID1645840 |
| Interferon beta | Homo sapiens (human) | Potency | 21.3174 | 0.0033 | 9.1582 | 39.8107 | AID1645842 |
| HLA class I histocompatibility antigen, B alpha chain | Homo sapiens (human) | Potency | 21.3174 | 0.0123 | 8.9648 | 39.8107 | AID1645842 |
| Inositol hexakisphosphate kinase 1 | Homo sapiens (human) | Potency | 21.3174 | 0.0123 | 8.9648 | 39.8107 | AID1645842 |
| cytochrome P450 2C9, partial | Homo sapiens (human) | Potency | 21.3174 | 0.0123 | 8.9648 | 39.8107 | AID1645842 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] | |||||||
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID1296008 | Cytotoxic Profiling of Annotated Libraries Using Quantitative High-Throughput Screening | 2020 | SLAS discovery : advancing life sciences R & D, 01, Volume: 25, Issue:1 | Cytotoxic Profiling of Annotated and Diverse Chemical Libraries Using Quantitative High-Throughput Screening. |
| AID1346986 | P-glycoprotein substrates identified in KB-3-1 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5 | A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
| AID1347159 | Primary screen GU Rhodamine qHTS for Zika virus inhibitors: Unlinked NS2B-NS3 protease assay | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49 | Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1347160 | Primary screen NINDS Rhodamine qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49 | Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1346987 | P-glycoprotein substrates identified in KB-8-5-11 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5 | A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
| AID977608 | Experimentally measured binding affinity data (IC50) for protein-ligand complexes derived from PDB | 2012 | ChemMedChem, Jul, Volume: 7, Issue:7 | Structural characterization and computer-aided optimization of a small-molecule inhibitor of the Arp2/3 complex, a key regulator of the actin cytoskeleton. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (4.35) | 29.6817 |
| 2010's | 18 (78.26) | 24.3611 |
| 2020's | 4 (17.39) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 25 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
| Substance | Description | Relationhip Strength | Studies | Trials | Classes | Roles |
|---|---|---|---|---|---|---|
| cytochalasin d | [no description available] | medium | 1 | 0 | ||
| y 27632 | [no description available] | medium | 1 | 0 | aromatic amide | |
| ck-869 | [no description available] | medium | 1 | 0 | ||
| nov 002 | [no description available] | medium | 3 | 0 | ||
| fura-2 | [no description available] | medium | 1 | 0 | ||
| inosine | [no description available] | medium | 1 | 0 | inosines; purines D-ribonucleoside | Escherichia coli metabolite; human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite |
| wiskostatin | [no description available] | medium | 2 | 0 | carbazoles; organobromine compound; secondary alcohol; tertiary amino compound | |
| fura-2-am | [no description available] | medium | 1 | 0 | ||
| uracil | [no description available] | medium | 1 | 0 | pyrimidine nucleobase; pyrimidone | allergen; Daphnia magna metabolite; Escherichia coli metabolite; human metabolite; mouse metabolite; prodrug; Saccharomyces cerevisiae metabolite |
| thiophenes | [no description available] | medium | 1 | 0 | mancude organic heteromonocyclic parent; monocyclic heteroarene; thiophenes; volatile organic compound | non-polar solvent |
| thiazoles | [no description available] | medium | 1 | 0 | 1,3-thiazoles; mancude organic heteromonocyclic parent; monocyclic heteroarene | |
| ck-0944636 | [no description available] | medium | 1 | 0 | ||
| cytochalasin b | [no description available] | medium | 1 | 0 | cytochalasin; lactam; lactone; organic heterotricyclic compound | actin polymerisation inhibitor; metabolite; mycotoxin; platelet aggregation inhibitor |
| nocodazole | [no description available] | medium | 1 | 0 | aromatic ketone; benzimidazoles; carbamate ester; thiophenes | antimitotic; antineoplastic agent; microtubule-destabilising agent; tubulin modulator |
| blister | [no description available] | medium | 1 | 0 | cyclic ketone; pyrroloquinoline; tertiary alcohol; tertiary alpha-hydroxy ketone | inhibitor |
| latrunculin a | [no description available] | low | 0 | 0 | cyclic hemiketal; macrolide; oxabicycloalkane; thiazolidinone | actin polymerisation inhibitor; metabolite; toxin |
| latrunculin b | [no description available] | low | 0 | 0 | cyclic hemiketal; macrolide; oxabicycloalkane; thiazolidinone | actin polymerisation inhibitor; metabolite; toxin |
| indoleacetamide | [no description available] | low | 0 | 0 | indoles; monocarboxylic acid amide; N-acylammonia | bacterial metabolite; fungal metabolite; plant metabolite |
| bisindolylmaleimide iii | [no description available] | low | 0 | 0 | indoles; maleimides | EC 2.7.11.13 (protein kinase C) inhibitor |
| bisindolylmaleimide iv | [no description available] | low | 0 | 0 | indoles; maleimides | |
| bisindolylmaleimide v | [no description available] | low | 0 | 0 | indoles | |
| chetomin | [no description available] | low | 0 | 0 | indoles; organic disulfide; organic heteropentacyclic compound | Chaetomium metabolite; immunosuppressive agent |
| dapi | [no description available] | low | 0 | 0 | indoles | fluorochrome |
| 3,3'-diindolylmethane | [no description available] | low | 0 | 0 | indoles | antineoplastic agent; P450 inhibitor |
| gö6983 | [no description available] | low | 0 | 0 | indoles; maleimides | |
| ic 261 | [no description available] | low | 0 | 0 | indoles | |
| indapamide | [no description available] | low | 0 | 0 | indoles; organochlorine compound; sulfonamide | antihypertensive agent; diuretic |
| indolepropanol phosphate | [no description available] | low | 0 | 0 | indoles; monoalkyl phosphate | |
| linopirdine | [no description available] | low | 0 | 0 | indoles | |
| pindolol | [no description available] | low | 0 | 0 | indoles; secondary amine | antiglaucoma drug; antihypertensive agent; beta-adrenergic antagonist; serotonergic antagonist; vasodilator agent |
| 3-[(3,5-dibromo-4-hydroxyphenyl)methylidene]-5-iodo-1H-indol-2-one | [no description available] | low | 0 | 0 | indoles | |
| ro 31-8220 | [no description available] | low | 0 | 0 | imidothiocarbamic ester; indoles; maleimides | EC 2.7.11.13 (protein kinase C) inhibitor |
| ici 204,219 | [no description available] | low | 0 | 0 | carbamate ester; indoles; N-sulfonylcarboxamide | anti-asthmatic agent; leukotriene antagonist |
| adrenochrome | [no description available] | low | 0 | 0 | indoles | |
| 5-bromoisatin | [no description available] | low | 0 | 0 | indoles | anticoronaviral agent |
| etryptamine | [no description available] | low | 0 | 0 | indoles | |
| hydroxytryptophol | [no description available] | low | 0 | 0 | indoles | |
| indole-3-carbaldehyde | [no description available] | low | 0 | 0 | heteroarenecarbaldehyde; indole alkaloid; indoles | bacterial metabolite; human xenobiotic metabolite; marine metabolite; plant metabolite |
| indican | [no description available] | low | 0 | 0 | aryl sulfate; indoles | human metabolite |
| indoline | [no description available] | low | 0 | 0 | indoles | |
| indoxyl acetate | [no description available] | low | 0 | 0 | indoles | |
| methoxytryptophol | [no description available] | low | 0 | 0 | indoles | |
| 5-methoxyindole | [no description available] | low | 0 | 0 | indoles | |
| iprindole | [no description available] | low | 0 | 0 | indoles | |
| mebhydroline | [no description available] | low | 0 | 0 | indoles | |
| molindone | [no description available] | low | 0 | 0 | indoles | |
| oxyphenisatin | [no description available] | low | 0 | 0 | indoles | |
| 5-Methoxyisatin | [no description available] | low | 0 | 0 | indoles | anticoronaviral agent |
| indalpine | [no description available] | low | 0 | 0 | indoles | |
| 5-bromo-4-chloro-3-indoxyl phosphate | [no description available] | low | 0 | 0 | aryl phosphate; indoles; organobromine compound; organochlorine compound | chromogenic compound |
| geneserine | [no description available] | low | 0 | 0 | indoles | |
| ropinirole hydrochloride | [no description available] | low | 0 | 0 | indoles | |
| tinazoline | [no description available] | low | 0 | 0 | indoles | |
| n-acetyltryptamine | [no description available] | low | 0 | 0 | acetamides; indoles | |
| mepindolol | [no description available] | low | 0 | 0 | indoles | |
| eletriptan | [no description available] | low | 0 | 0 | indoles; N-alkylpyrrolidine; sulfone | non-steroidal anti-inflammatory drug; serotonergic agonist; vasoconstrictor agent |
| 5-methoxyindole-3-carbaldehyde | [no description available] | low | 0 | 0 | indoles | |
| 6-chloroindole | [no description available] | low | 0 | 0 | indoles | |
| 5-Chloro-1H-indole-2,3-dione | [no description available] | low | 0 | 0 | indoles | anticoronaviral agent |
| 5-iodoisatin | [no description available] | low | 0 | 0 | indoles | anticoronaviral agent |
| lyngbyatoxin a | [no description available] | low | 0 | 0 | indoles | |
| indolactam v | [no description available] | low | 0 | 0 | indoles | |
| indo-1 | [no description available] | low | 0 | 0 | indoles | fluorochrome |
| ramosetron hydrochloride | [no description available] | low | 0 | 0 | indoles | |
| ramosetron | [no description available] | low | 0 | 0 | indoles | |
| 5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole | [no description available] | low | 0 | 0 | indoles | |
| echinuline | [no description available] | low | 0 | 0 | 2,5-diketopiperazines; indole alkaloid; indoles; olefinic compound | Aspergillus metabolite; marine metabolite; plant metabolite |
| luzindole | [no description available] | low | 0 | 0 | acetamides; indoles | melatonin receptor antagonist |
| almotriptan | [no description available] | low | 0 | 0 | indoles; sulfonamide; tertiary amine | non-steroidal anti-inflammatory drug; serotonergic agonist; vasoconstrictor agent |
| sb 200646 | [no description available] | low | 0 | 0 | indoles | |
| tilivalline | [no description available] | low | 0 | 0 | indole alkaloid; indoles; phenols; pyrrolobenzodiazepine | bacterial metabolite; microtubule-stabilising agent; toxin |
| asperlicin c | [no description available] | low | 0 | 0 | asperlicins; indoles; organic heterotetracyclic compound | Aspergillus metabolite; cholecystokinin antagonist |
| sandoz-21-009 | [no description available] | low | 0 | 0 | indoles | |
| pendolmycin | [no description available] | low | 0 | 0 | indoles | metabolite |
| cyanopindolol | [no description available] | low | 0 | 0 | indoles | |
| varespladib | [no description available] | low | 0 | 0 | aromatic ether; benzenes; dicarboxylic acid monoamide; indoles; monocarboxylic acid; primary carboxamide | anti-inflammatory drug; antidote; EC 3.1.1.4 (phospholipase A2) inhibitor |
| leukodopachrome | [no description available] | low | 0 | 0 | hydroxy monocarboxylic acid; indoles | metabolite |
| 3,3-bis(4-hydroxy-3-methylphenyl)-1H-indol-2-one | [no description available] | low | 0 | 0 | indoles | |
| 3-methyleneindolenine | [no description available] | low | 0 | 0 | indoles | metabolite |
| sb 216763 | [no description available] | low | 0 | 0 | indoles; maleimides | |
| enzastaurin | [no description available] | low | 0 | 0 | indoles; maleimides | |
| brevianamide f | [no description available] | low | 0 | 0 | dipeptide; indoles; pyrrolopyrazine | metabolite |
| 3-(hydroxyacetyl)indole | [no description available] | low | 0 | 0 | indoles | |
| roxindole | [no description available] | low | 0 | 0 | indoles | alpha-adrenergic antagonist; serotonergic drug |
| 5-Fluoroisatin | [no description available] | low | 0 | 0 | indoles | anticoronaviral agent |
| beta-indol-3-yl-glucoside | [no description available] | low | 0 | 0 | glycoside; indoles | |
| 2-methyl-3-(phenylmethylthio)-1H-indole | [no description available] | low | 0 | 0 | indoles | |
| indole-3-acetonitrile | [no description available] | low | 0 | 0 | indoles; nitrile | auxin; human xenobiotic metabolite; plant hormone; plant metabolite |
| 10H-[1]benzothiolo[3,2-b]indole | [no description available] | low | 0 | 0 | indoles | |
| 2,2,2-trifluoro-N-[2-(1H-indol-3-yl)ethyl]acetamide | [no description available] | low | 0 | 0 | indoles; secondary carboxamide; trifluoroacetamide | |
| physovenine | [no description available] | low | 0 | 0 | indoles | |
| dendrobine | [no description available] | low | 0 | 0 | indoles | |
| methyl indole-3-carboxylate | [no description available] | low | 0 | 0 | indoles; methyl ester | metabolite |
| 2-(1H-indol-3-ylthio)acetic acid | [no description available] | low | 0 | 0 | indoles | |
| 3-(4-pyridyl)-1h-indole | [no description available] | low | 0 | 0 | indoles | |
| 1-(2,3-dihydroindol-1-yl)-2-(5-pyridin-4-yl-2-tetrazolyl)ethanone | [no description available] | low | 0 | 0 | indoles | |
| 2-(6-cyano-1-indolyl)-N-cyclohexylacetamide | [no description available] | low | 0 | 0 | indoles | |
| 1-methyl-2-[(4-methyl-1-piperidinyl)methyl]-3-indolecarbonitrile | [no description available] | low | 0 | 0 | indoles | |
| 4-(1-methylsulfonyl-2,3-dihydroindol-5-yl)-N-(2-oxolanylmethyl)-2-thiazolamine | [no description available] | low | 0 | 0 | indoles | |
| N-[4-(2-methyl-1-methylsulfonyl-2,3-dihydroindol-5-yl)-2-thiazolyl]-2-thiophen-2-ylacetamide | [no description available] | low | 0 | 0 | indoles | |
| 1-[5-(2-amino-5-methyl-4-thiazolyl)-2,3-dihydroindol-1-yl]-1-butanone | [no description available] | low | 0 | 0 | indoles | |
| 2-(2-methyl-1H-indol-3-yl)ethanol | [no description available] | low | 0 | 0 | indoles | |
| 2-(2-ethyl-1-piperidinyl)-1-(2-methyl-1H-indol-3-yl)ethanone | [no description available] | low | 0 | 0 | indoles | |
| 1-(2,6-dimethyl-1H-indol-3-yl)-2-(1-pyrrolidinyl)ethanone | [no description available] | low | 0 | 0 | indoles | |
| 1-methyl-2-[(phenylthio)methyl]-3-indolecarbonitrile | [no description available] | low | 0 | 0 | indoles | |
| 1-(2,3-dihydroindol-1-yl)-2-(phenylthio)ethanone | [no description available] | low | 0 | 0 | indoles | |
| 2-(2,3-dihydroindol-1-yl)-N,N-dimethylethanamine | [no description available] | low | 0 | 0 | indoles | |
| 8-(1H-indol-3-ylmethylidene)-6,10-dioxaspiro[4.5]decane-7,9-dione | [no description available] | low | 0 | 0 | indoles | |
| N-(1-acetyl-2-chloro-3-indolyl)-2-chloroacetamide | [no description available] | low | 0 | 0 | indoles | |
| 4-(5-methoxy-1,2-dimethyl-3-indolyl)-2-thiazolamine | [no description available] | low | 0 | 0 | indoles | |
| N-(1-acetyl-2,3-dihydroindol-5-yl)-4-methylbenzamide | [no description available] | low | 0 | 0 | indoles | |
| oncrasin-1 | [no description available] | low | 0 | 0 | arenecarbaldehyde; indoles; monochlorobenzenes | antineoplastic agent; apoptosis inducer |
| 1-(2-methyl-1H-indol-3-yl)-2-(2-thiazolylamino)ethanone | [no description available] | low | 0 | 0 | indoles | |
| N-(2-fluorophenyl)-2-[3-(1-oxopropyl)-1-indolyl]acetamide | [no description available] | low | 0 | 0 | indoles | |
| 2-(3-acetyl-1-indolyl)-N-(2,4-dimethylphenyl)acetamide | [no description available] | low | 0 | 0 | indoles | |
| 4-amino-2-[[2-(2,3-dihydroindol-1-yl)-2-oxoethyl]thio]-5-pyrimidinecarboxylic acid ethyl ester | [no description available] | low | 0 | 0 | indoles | |
| LSM-33266 | [no description available] | low | 0 | 0 | indoles | |
| 1-oxo-3-(1-piperidinyl)-5,6,7,8-tetrahydropyrrolo[1,2-a]indole-2-carbonitrile | [no description available] | low | 0 | 0 | indoles | |
| [1-(2-phenoxyethyl)-3-indolyl]-(1-pyrrolidinyl)methanethione | [no description available] | low | 0 | 0 | indoles | |
| N-[4-(1-methylsulfonyl-2,3-dihydroindol-5-yl)-2-thiazolyl]acetamide | [no description available] | low | 0 | 0 | indoles | |
| 1-[2-(1H-indol-3-yl)ethyl]-5,6,7,8-tetrahydroquinolin-4-one | [no description available] | low | 0 | 0 | indoles | |
| N,N-diethylcarbamodithioic acid [2-(2-methyl-1H-indol-3-yl)-2-oxoethyl] ester | [no description available] | low | 0 | 0 | indoles | |
| 1-(3-phenoxypropyl)-3-indolecarbonitrile | [no description available] | low | 0 | 0 | indoles | |
| 1-[(3,4-dichlorophenyl)methyl]indole-2,3-dione | [no description available] | low | 0 | 0 | indoles | |
| 2-[[1-[(3-fluorophenyl)methyl]-3-indolyl]sulfonyl]-N-(5-methyl-3-isoxazolyl)acetamide | [no description available] | low | 0 | 0 | indoles | |
| 1-[2-(2,5-dimethyl-1H-indol-3-yl)ethyl]-3-methyl-1-(thiophen-2-ylmethyl)thiourea | [no description available] | low | 0 | 0 | indoles | |
| 2-(1H-indol-3-yl)-2-oxo-N-(2-thiazolyl)acetamide | [no description available] | low | 0 | 0 | indoles | |
| N-(2-furanylmethyl)-2-[3-(1-oxo-2-phenoxyethyl)-1-indolyl]acetamide | [no description available] | low | 0 | 0 | indoles | |
| 4-(1H-indol-3-yl)butanoic acid [2-(4-amino-1,3-dimethyl-2,6-dioxo-5-pyrimidinyl)-2-oxoethyl] ester | [no description available] | low | 0 | 0 | indoles | |
| 2,5-dimethyl-3-furancarboxylic acid [2-(2,3-dihydroindol-1-yl)-2-oxoethyl] ester | [no description available] | low | 0 | 0 | indoles | |
| 2-chloro-3-pyridinecarboxylic acid [2-(2,3-dihydroindol-1-yl)-2-oxoethyl] ester | [no description available] | low | 0 | 0 | indoles | |
| 4-(1H-indol-3-yl)butanoic acid [2-(3-methoxyanilino)-2-oxoethyl] ester | [no description available] | low | 0 | 0 | indoles | |
| 2-(2,3-dihydro-1H-inden-5-yloxy)-1-(2,3-dihydroindol-1-yl)ethanone | [no description available] | low | 0 | 0 | indoles | |
| 1H-indol-3-yl(pyridin-2-yl)methanol | [no description available] | low | 0 | 0 | indoles | |
| N-(1H-indol-5-yl)-2-thiophenecarboxamide | [no description available] | low | 0 | 0 | indoles | |
| 4-[[1-[(3,4-dichlorophenyl)methyl]-3-indolyl]-(3-methyl-5-oxo-1,2-dihydropyrazol-4-yl)methyl]-5-methyl-1,2-dihydropyrazol-3-one | [no description available] | low | 0 | 0 | indoles | |
| 2-methyl-3-[(2-methyl-1H-indol-3-yl)-(2-pyridinyl)methyl]-1H-indole | [no description available] | low | 0 | 0 | indoles | |
| N-[amino-[2-(1H-indol-3-yl)ethylimino]methyl]-4-chlorobenzamide | [no description available] | low | 0 | 0 | indoles | |
| 3-[2-(2,4-dimethyl-3-furanyl)-2-oxoethyl]-3-hydroxy-1-(2-phenylethyl)-2-indolone | [no description available] | low | 0 | 0 | indoles | |
| 1-[2-(hydroxymethyl)-1-benzimidazolyl]-3-(1-indolyl)-2-propanol | [no description available] | low | 0 | 0 | indoles | |
| 6-(2-chlorophenyl)-3-methyl-2-[4-morpholinyl(oxo)methyl]-1,5,6,7-tetrahydroindol-4-one | [no description available] | low | 0 | 0 | indoles | |
| 3-methyl-4-oxo-1,5,6,7-tetrahydroindole-2-carboxylic acid (4-methylcyclohexyl) ester | [no description available] | low | 0 | 0 | indoles | |
| 5-[[(5-ethyl-[1,2,4]triazino[5,6-b]indol-3-yl)thio]methyl]-2-furancarboxylic acid methyl ester | [no description available] | low | 0 | 0 | indoles | |
| N-[2-(diethylamino)ethyl]-5-[(5-fluoro-2-oxo-1H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide | [no description available] | low | 0 | 0 | indoles | |
| 2-[(prop-2-enylthio)-(4,5,6,7-tetrahydro-1H-indol-2-yl)methylidene]propanedinitrile | [no description available] | low | 0 | 0 | indoles | |
| 2-[[5-(dimethylsulfamoyl)-1H-indol-3-yl]methylidene]propanedioic acid diethyl ester | [no description available] | low | 0 | 0 | indoles | |
| 5-methyl-1-[3-(2-methylphenoxy)propyl]indole-2,3-dione | [no description available] | low | 0 | 0 | indoles | |
| N-[2-(1H-indol-3-yl)ethyl]-4-(phenylmethyl)-5-thieno[3,2-b]pyrrolecarboxamide | [no description available] | low | 0 | 0 | indoles | |
| 1-[cyclopropyl(oxo)methyl]-N-(2-hydroxyethyl)-N-(phenylmethyl)-2,3-dihydroindole-5-sulfonamide | [no description available] | low | 0 | 0 | indoles | |
| 5-bromo-1-(1-oxopropyl)-N,N-dipropyl-2,3-dihydroindole-7-sulfonamide | [no description available] | low | 0 | 0 | indoles | |
| 4-(1-methyl-3-indolyl)-N-propan-2-ylbutanamide | [no description available] | low | 0 | 0 | indoles | |
| 4-(2,3-dihydroindol-1-yl)-N-[3-(N-ethyl-3-methylanilino)propyl]-3-(1-imidazolyl)-4-oxobutanamide | [no description available] | low | 0 | 0 | indoles | |
| 1-[[5-bromo-1-[cyclopropyl(oxo)methyl]-2,3-dihydroindol-7-yl]sulfonyl]-4-piperidinecarboxylic acid ethyl ester | [no description available] | low | 0 | 0 | indoles | |
| N-[2-(2-methyl-1-indolyl)ethyl]benzamide | [no description available] | low | 0 | 0 | indoles | |
| 3-[[5-bromo-1-[cyclopropyl(oxo)methyl]-2,3-dihydroindol-7-yl]sulfonyl]-N-[(5-methyl-2-furanyl)methyl]propanamide | [no description available] | low | 0 | 0 | indoles | |
| acetic acid [2-(1-acetyl-6-indolyl)-2-oxoethyl] ester | [no description available] | low | 0 | 0 | indoles | |
| N-[2-(1-cyclohexenyl)ethyl]-1-[cyclopropyl(oxo)methyl]-2,3-dihydroindole-5-sulfonamide | [no description available] | low | 0 | 0 | indoles | |
| 4-[2-[[1-[(2-methylphenyl)methyl]-3-indolyl]sulfonyl]-1-oxoethyl]-1-piperazinecarboxylic acid ethyl ester | [no description available] | low | 0 | 0 | indoles | |
| N-[4-(dimethylamino)phenyl]-2-(1-oxo-[1,2,4]triazino[4,5-a]indol-2-yl)acetamide | [no description available] | low | 0 | 0 | indoles | |
| N-(3-methoxyphenyl)-2-(1-methyl-3-indolyl)acetamide | [no description available] | low | 0 | 0 | indoles | |
| cyclobutyl-[5-[(2-ethyl-1-piperidinyl)sulfonyl]-2,3-dihydroindol-1-yl]methanone | [no description available] | low | 0 | 0 | indoles | |
| n-(1-methyl-5-indolyl)-n'-(3-methyl-5-isothiazolyl)urea | [no description available] | low | 0 | 0 | 1,2-thiazoles; indoles; ureas | receptor modulator; serotonergic antagonist |
| n-pentanoyl-2-benzyltryptamine | [no description available] | low | 0 | 0 | indoles | |
| 2-[[1-(phenylmethyl)-3-indolyl]thio]-N-(2-thiazolyl)acetamide | [no description available] | low | 0 | 0 | indoles | |
| [1-[2-(2-methylphenoxy)ethyl]-3-indolyl]-(4-methyl-1-piperazinyl)methanethione | [no description available] | low | 0 | 0 | indoles | |
| 1-(Chloroacetyl)-3-(1H-indol-3-yl)-5-(4-methoxyphenyl)-4,5-dihydro-1H-pyrazol-4-ol | [no description available] | low | 0 | 0 | indoles | anticoronaviral agent |
| N-[(1,2-dimethyl-5-indolyl)methyl]-2-methyl-3-nitrobenzamide | [no description available] | low | 0 | 0 | indoles | |
| N-(2-furanylmethyl)-2-[[5-[(2-methyl-1H-indol-3-yl)methyl]-1,3,4-oxadiazol-2-yl]thio]acetamide | [no description available] | low | 0 | 0 | indoles | |
| l 663536 | [no description available] | low | 0 | 0 | aryl sulfide; indoles; monocarboxylic acid; monochlorobenzenes | antineoplastic agent; EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor; leukotriene antagonist |
| 2-[(1-methyl-3-indolyl)thio]-N-(2-thiazolyl)acetamide | [no description available] | low | 0 | 0 | indoles | |
| Nb-Palmitoyltryptamine | [no description available] | low | 0 | 0 | indoles | |
| rs 17053 | [no description available] | low | 0 | 0 | indoles | |
| N-[2-(2-chlorophenoxy)ethyl]-2-(1H-indol-3-yl)-2-oxoacetamide | [no description available] | low | 0 | 0 | indoles | |
| 1-(1H-indol-3-yl)-2-[(6-methyl-2-nitro-3-pyridinyl)oxy]ethanone | [no description available] | low | 0 | 0 | indoles | |
| 1-[2-(5-chloro-2-methyl-1H-indol-3-yl)ethyl]-3-ethyl-1-(2-furanylmethyl)thiourea | [no description available] | low | 0 | 0 | indoles | |
| 5-bromo-N-[(1,2-dimethyl-5-indolyl)methyl]-2-furancarboxamide | [no description available] | low | 0 | 0 | indoles | |
| 1-[(1,2-dimethyl-5-indolyl)methyl]-3-(phenylmethyl)thiourea | [no description available] | low | 0 | 0 | indoles | |
| 4-chloro-N-[2-(1H-indol-3-yl)-1-(6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepin-3-yl)ethyl]benzamide | [no description available] | low | 0 | 0 | indoles | |
| 1-cyclohexyl-3-[(1,2-dimethyl-5-indolyl)methyl]urea | [no description available] | low | 0 | 0 | indoles | |
| 5-bromo-N-[2-(2-methyl-1-indolyl)ethyl]-2-furancarboxamide | [no description available] | low | 0 | 0 | indoles | |
| le 300 | [no description available] | low | 0 | 0 | indoles | |
| 4-[(1,2-dimethyl-5-indolyl)methylamino]-4-oxobutanoic acid | [no description available] | low | 0 | 0 | indoles | |
| 5-Nitroisatin | [no description available] | low | 0 | 0 | indoles | anticoronaviral agent |
| 1-[2-(2,4-dichlorophenyl)-2-(1H-indol-3-yl)ethyl]-3-[3-(dimethylamino)propyl]thiourea | [no description available] | low | 0 | 0 | indoles | |
| N-[2-[4-(dimethylamino)phenyl]-2-(1H-indol-3-yl)ethyl]benzamide | [no description available] | low | 0 | 0 | indoles | |
| 2,6-difluoro-N-[2-[3-[(2-fluorophenyl)methylthio]-1-indolyl]ethyl]benzamide | [no description available] | low | 0 | 0 | indoles | |
| ro 60-0175 | [no description available] | low | 0 | 0 | indoles; organochlorine compound; organofluorine compound; primary amino compound | |
| N-[(1,2-dimethyl-5-indolyl)methyl]-2-(4-nitrophenyl)acetamide | [no description available] | low | 0 | 0 | indoles | |
| 2-[[4-amino-5-(3,4-dimethoxyphenyl)-1,2,4-triazol-3-yl]thio]-1-(1H-indol-3-yl)-2-phenylethanone | [no description available] | low | 0 | 0 | indoles | |
| 1-acetyl-N-[3-(N-ethyl-3-methylanilino)propyl]-2,3-dihydroindole-5-sulfonamide | [no description available] | low | 0 | 0 | indoles | |
| 3-[3-[(5-ethyl-[1,2,4]triazino[5,6-b]indol-3-yl)thio]propyl]-1H-benzimidazol-2-one | [no description available] | low | 0 | 0 | indoles | |
| koumine | [no description available] | low | 0 | 0 | indoles | |
| AG-370 | [no description available] | low | 0 | 0 | indoles | |
| (6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid | [no description available] | low | 0 | 0 | dihydroxy monocarboxylic acid; indoles; organofluorine compound | |
| apaziquone | [no description available] | low | 0 | 0 | indoles | |
| amaranthin betacyanin | [no description available] | low | 0 | 0 | disaccharide derivative; indoles; olefinic compound; tetrahydropyridine | biological pigment; plant metabolite |
| (5-ethyl-8-methyl-[1,2,4]triazino[5,6-b]indol-3-yl)hydrazine | [no description available] | low | 0 | 0 | indoles | |
| chaetoglobosin A | [no description available] | low | 0 | 0 | cytochalasan alkaloid; epoxide; indoles; macrocycle; secondary alpha-hydroxy ketone | Chaetomium metabolite |
| LSM-18452 | [no description available] | low | 0 | 0 | indoles | |
| (2R,4R)-4-(1-acetyl-3-indolyl)-2-[[4-(hydroxymethyl)phenyl]methoxy]-N-(phenylmethyl)-3,4-dihydro-2H-pyran-6-carboxamide | [no description available] | low | 0 | 0 | indoles | |
| vilazodone | [no description available] | low | 0 | 0 | 1-benzofurans; indoles; monocarboxylic acid amide; N-alkylpiperazine; N-arylpiperazine; nitrile | antidepressant; serotonergic agonist; serotonin uptake inhibitor |
| cyclo(glycyltryptophyl) | [no description available] | low | 0 | 0 | indoles | metabolite |
| 2-[(1R,3S)-3-(7-bromo-2-methyl-1H-indol-3-yl)-2,2-dimethylcyclopropyl]acetonitrile | [no description available] | low | 0 | 0 | indoles | |
| (11S,14S)-Cyclo-(L-Trp-L-Phe) | [no description available] | low | 0 | 0 | indoles | Aspergillus metabolite |
| LSM-3706 | [no description available] | low | 0 | 0 | indoles | |
| LSM-3511 | [no description available] | low | 0 | 0 | indoles | |
| LSM-2818 | [no description available] | low | 0 | 0 | indoles | |
| tryprostatin b | [no description available] | low | 0 | 0 | dipeptide; indole alkaloid; indoles; pyrrolopyrazine | |
| l 779976 | [no description available] | low | 0 | 0 | benzimidazoles; indoles; piperidinecarboxamide; primary amino compound; secondary carboxamide | neuroprotective agent; somatostatin receptor agonist |
| tmc-95a | [no description available] | low | 0 | 0 | indoles; lactam; macrocycle; phenols; secondary alcohol; tertiary alcohol | antimicrobial agent; antineoplastic agent; bacterial metabolite; fungal metabolite; proteasome inhibitor |
| nematophin | [no description available] | low | 0 | 0 | indoles | |
| molindone hydrochloride | [no description available] | low | 0 | 0 | indoles | |
| varespladib methyl | [no description available] | low | 0 | 0 | aromatic ether; benzenes; indoles; methyl ester; primary carboxamide | anti-inflammatory drug; antidote; EC 3.1.1.4 (phospholipase A2) inhibitor; prodrug |
| am 694 | [no description available] | low | 0 | 0 | aromatic ketone; indoles; organofluorine compound; organoiodine compound; synthetic cannabinoid | cannabinoid receptor agonist |
| tryprostatin a | [no description available] | low | 0 | 0 | aromatic ether; dipeptide; indole alkaloid; indoles; pyrrolopyrazine | breast cancer resistance protein inhibitor |
| way-362450 | [no description available] | low | 0 | 0 | indoles | |
| fumiquinazoline f | [no description available] | low | 0 | 0 | fumiquinazoline; indoles; pyrazinoquinazoline | |
| 5-chloro-2-methyl-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1h-indole | [no description available] | low | 0 | 0 | indoles | |
| a 443654 | [no description available] | low | 0 | 0 | indoles | |
| noradrenochrome | [no description available] | low | 0 | 0 | indoles | |
| sotrastaurin | [no description available] | low | 0 | 0 | indoles; maleimides; N-alkylpiperazine; N-arylpiperazine; quinazolines | anticoronaviral agent; EC 2.7.11.13 (protein kinase C) inhibitor; immunosuppressive agent |
| tmc-95b | [no description available] | low | 0 | 0 | indoles; lactam; macrocycle; phenols; secondary alcohol; tertiary alcohol | antimicrobial agent; antineoplastic agent; fungal metabolite; proteasome inhibitor |
| chromopyrrolic acid | [no description available] | low | 0 | 0 | indoles; pyrroledicarboxylic acid | bacterial metabolite |
| arq 197 | [no description available] | low | 0 | 0 | indoles | |
| quisinostat | [no description available] | low | 0 | 0 | indoles | |
| pf-562,271 | [no description available] | low | 0 | 0 | indoles | |
| Dihydro-beta-erythroidine hydrobromide | [no description available] | low | 0 | 0 | indoles | |
| N-[5-(2,3-dihydroindol-1-ylsulfonyl)-1,3,4-thiadiazol-2-yl]-3-methylbutanamide | [no description available] | low | 0 | 0 | indoles | |
| complestatin | [no description available] | low | 0 | 0 | cyclic ether; heterodetic cyclic peptide; indoles; organic heterobicyclic compound; organochlorine compound; peptide antibiotic; polyphenol | anti-HIV-1 agent; antimicrobial agent; HIV-1 integrase inhibitor; metabolite |
| neuroprotectin a | [no description available] | low | 0 | 0 | cyclic ether; heterodetic cyclic peptide; indoles; organochlorine compound; polyphenol | HIV-1 integrase inhibitor; metabolite |
| 2-[3-[[2-oxo-2-(1-pyrrolidinyl)ethyl]thio]-1-indolyl]-N,N-di(propan-2-yl)acetamide | [no description available] | low | 0 | 0 | indoles | |
| 1-[3-[(2R,4R)-2-[[4-(hydroxymethyl)phenyl]methoxy]-6-[oxo-[4-(phenylmethyl)-1-piperazinyl]methyl]-3,4-dihydro-2H-pyran-4-yl]-1-indolyl]ethanone | [no description available] | low | 0 | 0 | indoles | |
| 3-[(1-methyl-3-indolyl)methylidene]-1H-pyrrolo[3,2-b]pyridin-2-one | [no description available] | low | 0 | 0 | indoles | |
| 2-[1-[2-(diethylamino)-2-oxoethyl]-3-indolyl]-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-oxoacetamide | [no description available] | low | 0 | 0 | indoles | |
| 1-[(2-oxo-1,3-dihydroindol-5-yl)sulfonyl]-4-piperidinecarboxylic acid ethyl ester | [no description available] | low | 0 | 0 | indoles | |
| N-(4-propan-2-ylphenyl)-1-[(1,3,3-trimethyl-2-oxo-5-indolyl)sulfonyl]-4-piperidinecarboxamide | [no description available] | low | 0 | 0 | indoles | |
| N-[4-[1-(1-oxopropyl)-2,3-dihydroindol-5-yl]-2-thiazolyl]-2-furancarboxamide | [no description available] | low | 0 | 0 | indoles | |
| cink4 | [no description available] | low | 0 | 0 | indoles | |
| chondramide c | [no description available] | low | 0 | 0 | chondramide; indoles; phenols | antineoplastic agent; bacterial metabolite |
| 2-[[1-[(3-chlorophenyl)methyl]-3-indolyl]sulfonyl]-N-(5-methyl-3-isoxazolyl)acetamide | [no description available] | low | 0 | 0 | indoles | |
| 2-[[1-[(3-bromophenyl)methyl]-3-indolyl]sulfonyl]-N-(5-methyl-3-isoxazolyl)acetamide | [no description available] | low | 0 | 0 | indoles | |
| wasalexin a | [no description available] | low | 0 | 0 | indoles | |
| chondramide a | [no description available] | low | 0 | 0 | chondramide; indoles; phenols | antineoplastic agent; bacterial metabolite |
| (3R)-4-[2-(1H-indol-4-yl)-6-(1-methylsulfonylcyclopropyl)-4-pyrimidinyl]-3-methylmorpholine | [no description available] | low | 0 | 0 | indoles | |
| gsk2656157 | [no description available] | low | 0 | 0 | biaryl; indoles; methylpyridines; organofluorine compound; pyrrolopyrimidine; tertiary carboxamide | antineoplastic agent; EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitor; PERK inhibitor |
| AZD3463 | [no description available] | low | 0 | 0 | aminopiperidine; aminopyrimidine; indoles; monomethoxybenzene; organochlorine compound; secondary amino compound; tertiary amino compound | antineoplastic agent; apoptosis inducer; autophagy inducer; EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor |
| osimertinib | [no description available] | low | 0 | 0 | acrylamides; aminopyrimidine; biaryl; indoles; monomethoxybenzene; secondary amino compound; secondary carboxamide; substituted aniline; tertiary amino compound | antineoplastic agent; epidermal growth factor receptor antagonist |
| acarbose | [no description available] | low | 0 | 0 | chondramide; indoles; organochlorine compound; phenols | antineoplastic agent; bacterial metabolite |
| chondramide d | [no description available] | low | 0 | 0 | chondramide; indoles; phenols | antineoplastic agent; bacterial metabolite |
| THZ531 | [no description available] | low | 0 | 0 | aminopyrimidine; enamide; indoles; N-acylpiperidine; organochlorine compound; secondary amino compound; secondary carboxamide | antineoplastic agent; apoptosis inducer; EC 2.7.11.22 (cyclin-dependent kinase) inhibitor |
| lugdunin | [no description available] | low | 0 | 0 | homodetic cyclic peptide; indoles; macrocycle; peptide antibiotic; thiazolidines | human metabolite; rat metabolite |
| tegaserod | [no description available] | low | 0 | 0 | carboxamidine; guanidines; hydrazines; indoles | gastrointestinal drug; serotonergic agonist |
| brassilexin | [no description available] | low | 0 | 0 | indoles | |
| indolmycin | [no description available] | low | 0 | 0 | 1,3-oxazoles; indoles; secondary amino compound | antibacterial agent; antimicrobial agent; bacterial metabolite; EC 6.1.1.2 (tryptophan--tRNA ligase) inhibitor |
| N'-(1h-indol-3-ylmethylene)benzohydrazide | [no description available] | low | 0 | 0 | indoles | |
| benefin | [no description available] | low | 0 | 0 | C-nitro compound; organofluorine compound; substituted aniline; tertiary amino compound | agrochemical; herbicide |
| celecoxib | [no description available] | low | 0 | 0 | organofluorine compound; pyrazoles; sulfonamide; toluenes | cyclooxygenase 2 inhibitor; geroprotector; non-narcotic analgesic; non-steroidal anti-inflammatory drug |
| cgs 12066 | [no description available] | low | 0 | 0 | N-arylpiperazine; organofluorine compound; pyrroloquinoxaline | serotonergic agonist |
| citalopram | [no description available] | low | 0 | 0 | 2-benzofurans; cyclic ether; nitrile; organofluorine compound; tertiary amino compound | |
| diflunisal | [no description available] | low | 0 | 0 | monohydroxybenzoic acid; organofluorine compound | non-narcotic analgesic; non-steroidal anti-inflammatory drug |
| droperidol | [no description available] | low | 0 | 0 | aromatic ketone; benzimidazoles; organofluorine compound | anaesthesia adjuvant; antiemetic; dopaminergic antagonist; first generation antipsychotic |
| enflurane | [no description available] | low | 0 | 0 | ether; organochlorine compound; organofluorine compound | anaesthetic |
| carbonyl cyanide p-trifluoromethoxyphenylhydrazone | [no description available] | low | 0 | 0 | aromatic ether; hydrazone; nitrile; organofluorine compound | ATP synthase inhibitor; geroprotector; ionophore |
| flecainide | [no description available] | low | 0 | 0 | aromatic ether; monocarboxylic acid amide; organofluorine compound; piperidines | anti-arrhythmia drug |
| flucytosine | [no description available] | low | 0 | 0 | aminopyrimidine; nucleoside analogue; organofluorine compound; pyrimidine antifungal drug; pyrimidone | prodrug |
| fludiazepam | [no description available] | low | 0 | 0 | 1,4-benzodiazepinone; organochlorine compound; organofluorine compound | anxiolytic drug |
| flufenamic acid | [no description available] | low | 0 | 0 | aromatic amino acid; organofluorine compound | antipyretic; EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor; non-narcotic analgesic; non-steroidal anti-inflammatory drug |
| fluphenazine | [no description available] | low | 0 | 0 | N-alkylpiperazine; organofluorine compound; phenothiazines | anticoronaviral agent; dopaminergic antagonist; phenothiazine antipsychotic drug |
| flumazenil | [no description available] | low | 0 | 0 | ethyl ester; imidazobenzodiazepine; organofluorine compound | antidote to benzodiazepine poisoning; GABA antagonist |
| flumequine | [no description available] | low | 0 | 0 | 3-oxo monocarboxylic acid; organofluorine compound; pyridoquinoline; quinolone antibiotic | |
| fluorouracil | [no description available] | low | 0 | 0 | nucleobase analogue; organofluorine compound | antimetabolite; antineoplastic agent; environmental contaminant; immunosuppressive agent; radiosensitizing agent; xenobiotic |
| fluphenazine depot | [no description available] | low | 0 | 0 | decanoate ester; N-alkylpiperazine; organofluorine compound; phenothiazines | dopaminergic antagonist; phenothiazine antipsychotic drug; prodrug |
| vanoxerine | [no description available] | low | 0 | 0 | ether; N-alkylpiperazine; organofluorine compound; tertiary amino compound | dopamine uptake inhibitor |
| haloperidol | [no description available] | low | 0 | 0 | aromatic ketone; hydroxypiperidine; monochlorobenzenes; organofluorine compound; tertiary alcohol | antidyskinesia agent; antiemetic; dopaminergic antagonist; first generation antipsychotic; serotonergic antagonist |
| halothane | [no description available] | low | 0 | 0 | haloalkane; organobromine compound; organochlorine compound; organofluorine compound | inhalation anaesthetic |
| isoflurane | [no description available] | low | 0 | 0 | organofluorine compound | inhalation anaesthetic |
| ketanserin | [no description available] | low | 0 | 0 | aromatic ketone; organofluorine compound; piperidines; quinazolines | alpha-adrenergic antagonist; antihypertensive agent; cardiovascular drug; EC 3.4.21.26 (prolyl oligopeptidase) inhibitor; serotonergic antagonist |
| mefloquine hydrochloride | [no description available] | low | 0 | 0 | organofluorine compound; piperidines; quinolines; secondary alcohol | |
| methoxyflurane | [no description available] | low | 0 | 0 | ether; organochlorine compound; organofluorine compound | hepatotoxic agent; inhalation anaesthetic; nephrotoxic agent; non-narcotic analgesic |
| ofloxacin | [no description available] | low | 0 | 0 | 3-oxo monocarboxylic acid; N-arylpiperazine; N-methylpiperazine; organofluorine compound; oxazinoquinoline | |
| pantoprazole | [no description available] | low | 0 | 0 | aromatic ether; benzimidazoles; organofluorine compound; pyridines; sulfoxide | anti-ulcer drug; EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor; environmental contaminant; xenobiotic |
| pipamperone | [no description available] | low | 0 | 0 | aromatic ketone; bipiperidines; monocarboxylic acid amide; organofluorine compound; tertiary amino compound | dopaminergic antagonist; first generation antipsychotic; serotonergic antagonist |
| risperidone | [no description available] | low | 0 | 0 | 1,2-benzoxazoles; heteroarylpiperidine; organofluorine compound; pyridopyrimidine | alpha-adrenergic antagonist; dopaminergic antagonist; EC 3.4.21.26 (prolyl oligopeptidase) inhibitor; H1-receptor antagonist; psychotropic drug; second generation antipsychotic; serotonergic antagonist |
| ritanserin | [no description available] | low | 0 | 0 | organofluorine compound; piperidines; thiazolopyrimidine | antidepressant; antipsychotic agent; anxiolytic drug; dopaminergic antagonist; EC 3.4.21.26 (prolyl oligopeptidase) inhibitor; serotonergic antagonist |
| sb 220025 | [no description available] | low | 0 | 0 | aminopyrimidine; imidazoles; organofluorine compound; piperidines | angiogenesis inhibitor; anti-inflammatory agent; EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor |
| sb 202190 | [no description available] | low | 0 | 0 | imidazoles; organofluorine compound; phenols; pyridines | apoptosis inducer; EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor |
| sevoflurane | [no description available] | low | 0 | 0 | ether; organofluorine compound | central nervous system depressant; inhalation anaesthetic; platelet aggregation inhibitor |
| fluoroacetic acid | [no description available] | low | 0 | 0 | haloacetic acid; organofluorine compound | EC 4.2.1.3 (aconitate hydratase) inhibitor |
| spiperone | [no description available] | low | 0 | 0 | aromatic ketone; azaspiro compound; organofluorine compound; piperidines; tertiary amino compound | alpha-adrenergic antagonist; antipsychotic agent; dopaminergic antagonist; psychotropic drug; serotonergic antagonist |
| gatifloxacin | [no description available] | low | 0 | 0 | N-arylpiperazine; organofluorine compound; quinolinemonocarboxylic acid; quinolone antibiotic; quinolone | antiinfective agent; antimicrobial agent; EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor |
| tosufloxacin | [no description available] | low | 0 | 0 | 1,8-naphthyridine derivative; amino acid; aminopyrrolidine; monocarboxylic acid; organofluorine compound; primary amino compound; quinolone antibiotic; tertiary amino compound | |
| trifluoperazine | [no description available] | low | 0 | 0 | N-alkylpiperazine; N-methylpiperazine; organofluorine compound; phenothiazines | antiemetic; calmodulin antagonist; dopaminergic antagonist; EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor; EC 5.3.3.5 (cholestenol Delta-isomerase) inhibitor; phenothiazine antipsychotic drug |
| triflupromazine | [no description available] | low | 0 | 0 | organofluorine compound; phenothiazines; tertiary amine | anticoronaviral agent; antiemetic; dopaminergic antagonist; first generation antipsychotic |
| zardaverine | [no description available] | low | 0 | 0 | organofluorine compound; pyridazinone | anti-asthmatic drug; bronchodilator agent; EC 3.1.4.* (phosphoric diester hydrolase) inhibitor; peripheral nervous system drug |
| floxuridine | [no description available] | low | 0 | 0 | nucleoside analogue; organofluorine compound; pyrimidine 2'-deoxyribonucleoside | antimetabolite; antineoplastic agent; antiviral drug; radiosensitizing agent |
| trifluridine | [no description available] | low | 0 | 0 | nucleoside analogue; organofluorine compound; pyrimidine 2'-deoxyribonucleoside | antimetabolite; antineoplastic agent; antiviral drug; EC 2.1.1.45 (thymidylate synthase) inhibitor |
| dinitrofluorobenzene | [no description available] | low | 0 | 0 | C-nitro compound; organofluorine compound | agrochemical; allergen; chromatographic reagent; EC 2.7.3.2 (creatine kinase) inhibitor; protein-sequencing agent; spectrophotometric reagent |
| 1,1-difluoroethylene | [no description available] | low | 0 | 0 | olefinic compound; organofluorine compound | |
| 1,1,1-trifluoro-2-chloroethane | [no description available] | low | 0 | 0 | organofluorine compound | |
| chloropentafluoroethane | [no description available] | low | 0 | 0 | organochlorine compound; organofluorine compound | |
| 2-fluoroadenosine | [no description available] | low | 0 | 0 | adenosines; organofluorine compound | |
| perfluorotributylamine | [no description available] | low | 0 | 0 | organofluorine compound | blood substitute; greenhouse gas; solvent |
| 5-fluorouridine | [no description available] | low | 0 | 0 | organofluorine compound; uridines | mutagen |
| 5-fluorotryptophan | [no description available] | low | 0 | 0 | non-proteinogenic alpha-amino acid; organofluorine compound; tryptophan derivative | |
| bromochlorodifluoromethane | [no description available] | low | 0 | 0 | one-carbon compound; organobromine compound; organochlorine compound; organofluorine compound | |
| difluoroacetic acid | [no description available] | low | 0 | 0 | monocarboxylic acid; organofluorine compound | |
| fluroxene | [no description available] | low | 0 | 0 | organofluorine compound | |
| 2,3,4,5,6-pentafluorobenzyl alcohol | [no description available] | low | 0 | 0 | benzyl alcohols; organofluorine compound | |
| 2-fluoroadenine | [no description available] | low | 0 | 0 | organofluorine compound; purines | antineoplastic agent |
| n-dichlorofluoromethylthio-n',n'-dimethyl-n-p-tolylsulfamide | [no description available] | low | 0 | 0 | organochlorine compound; organofluorine compound; phenylsulfamide fungicide; sulfamides | antifungal agrochemical; genotoxin |
| hexafluoroisopropanol | [no description available] | low | 0 | 0 | organofluorine compound; secondary alcohol | drug metabolite |
| dichlofluanid | [no description available] | low | 0 | 0 | organochlorine compound; organofluorine compound; phenylsulfamide fungicide; sulfamides | acaricide; antifungal agrochemical |
| pimozide | [no description available] | low | 0 | 0 | benzimidazoles; heteroarylpiperidine; organofluorine compound | antidyskinesia agent; dopaminergic antagonist; first generation antipsychotic; H1-receptor antagonist; serotonergic antagonist |
| 5-fluorocytidine | [no description available] | low | 0 | 0 | cytidines; organofluorine compound | |
| doxifluridine | [no description available] | low | 0 | 0 | organofluorine compound; pyrimidine 5'-deoxyribonucleoside | antimetabolite; antineoplastic agent; prodrug |
| fludarabine phosphate | [no description available] | low | 0 | 0 | nucleoside analogue; organofluorine compound; purine arabinonucleoside monophosphate | antimetabolite; antineoplastic agent; antiviral agent; DNA synthesis inhibitor; immunosuppressive agent; prodrug |
| flubendazole | [no description available] | low | 0 | 0 | aromatic ketone; benzimidazoles; carbamate ester; organofluorine compound | antinematodal drug; teratogenic agent |
| flunixin | [no description available] | low | 0 | 0 | aminopyridine; organofluorine compound; pyridinemonocarboxylic acid | antipyretic; EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor; non-narcotic analgesic; non-steroidal anti-inflammatory drug |
| desflurane | [no description available] | low | 0 | 0 | organofluorine compound | inhalation anaesthetic |
| paroxetine | [no description available] | low | 0 | 0 | aromatic ether; benzodioxoles; organofluorine compound; piperidines | antidepressant; anxiolytic drug; hepatotoxic agent; P450 inhibitor; serotonin uptake inhibitor |
| acifluorfen | [no description available] | low | 0 | 0 | aromatic ether; benzoic acids; C-nitro compound; monocarboxylic acid; organochlorine compound; organofluorine compound | agrochemical; EC 1.3.3.4 (protoporphyrinogen oxidase) inhibitor; herbicide |
| triflumuron | [no description available] | low | 0 | 0 | aromatic ether; benzoylurea insecticide; monochlorobenzenes; organofluorine compound | |
| 4,5-amino-3,5-dichloro-6-fluoro-2-pyridinyloxyacetic acid | [no description available] | low | 0 | 0 | aminopyridine; aromatic ether; monocarboxylic acid; organochlorine compound; organofluorine compound | environmental contaminant; herbicide; xenobiotic |
| haloxyfop | [no description available] | low | 0 | 0 | aromatic ether; monocarboxylic acid; organochlorine compound; organofluorine compound; pyridines | |
| fluazifop-butyl | [no description available] | low | 0 | 0 | aromatic ether; carboxylic ester; organofluorine compound; pyridines | |
| fomesafen | [no description available] | low | 0 | 0 | aromatic ether; C-nitro compound; monochlorobenzenes; N-sulfonylcarboxamide; organofluorine compound; phenols | agrochemical; EC 1.3.3.4 (protoporphyrinogen oxidase) inhibitor; herbicide |
| temafloxacin | [no description available] | low | 0 | 0 | amino acid; monocarboxylic acid; N-arylpiperazine; organofluorine compound; quinolone antibiotic; quinolone; secondary amino compound; tertiary amino compound | |
| sertindole | [no description available] | low | 0 | 0 | heteroarylpiperidine; imidazolidinone; organochlorine compound; organofluorine compound; phenylindole | alpha-adrenergic antagonist; H1-receptor antagonist; second generation antipsychotic; serotonergic antagonist |
| gemcitabine hydrochloride | [no description available] | low | 0 | 0 | hydrochloride; organofluorine compound | anticoronaviral agent; antimetabolite; antineoplastic agent; antiviral drug; EC 1.17.4.1 (ribonucleoside-diphosphate reductase) inhibitor; immunosuppressive agent; radiosensitizing agent |
| gemcitabine | [no description available] | low | 0 | 0 | organofluorine compound; pyrimidine 2'-deoxyribonucleoside | antimetabolite; antineoplastic agent; antiviral drug; DNA synthesis inhibitor; EC 1.17.4.1 (ribonucleoside-diphosphate reductase) inhibitor; environmental contaminant; immunosuppressive agent; photosensitizing agent; prodrug; radiosensitizing agent; xenobiotic |
| emtricitabine | [no description available] | low | 0 | 0 | monothioacetal; nucleoside analogue; organofluorine compound; pyrimidone | antiviral drug; HIV-1 reverse transcriptase inhibitor |
| capecitabine | [no description available] | low | 0 | 0 | carbamate ester; cytidines; organofluorine compound | antimetabolite; antineoplastic agent; prodrug |
| 4-fluorofentanyl | [no description available] | low | 0 | 0 | monocarboxylic acid amide; organofluorine compound; piperidines | |
| efavirenz | [no description available] | low | 0 | 0 | acetylenic compound; benzoxazine; cyclopropanes; organochlorine compound; organofluorine compound | antiviral drug; HIV-1 reverse transcriptase inhibitor |
| heptafluorobutyric anhydride | [no description available] | low | 0 | 0 | acyclic carboxylic anhydride; organofluorine compound | chromatographic reagent |
| perfluorotripropylamine | [no description available] | low | 0 | 0 | organofluorine compound | blood substitute |
| 3-fluoropyruvate | [no description available] | low | 0 | 0 | 2-oxo monocarboxylic acid; organofluorine compound | |
| spiramide | [no description available] | low | 0 | 0 | aromatic ether; azaspiro compound; organofluorine compound; piperidines; tertiary amino compound | dopaminergic antagonist; serotonergic antagonist |
| flunoxaprofen | [no description available] | low | 0 | 0 | 1,3-benzoxazoles; monocarboxylic acid; organofluorine compound | antirheumatic drug; hepatotoxic agent; non-steroidal anti-inflammatory drug; protein kinase C agonist |
| halopropane | [no description available] | low | 0 | 0 | organofluorine compound | |
| enrofloxacin | [no description available] | low | 0 | 0 | cyclopropanes; N-alkylpiperazine; N-arylpiperazine; organofluorine compound; quinolinemonocarboxylic acid; quinolone | antibacterial agent; antimicrobial agent; antineoplastic agent |
| flurithromycin | [no description available] | low | 0 | 0 | cyclic ketone; erythromycin derivative; organofluorine compound; semisynthetic derivative | antibacterial drug |
| nebivolol | [no description available] | low | 0 | 0 | chromanes; diol; organofluorine compound; secondary alcohol; secondary amino compound | |
| hp 873 | [no description available] | low | 0 | 0 | 1,2-benzoxazoles; aromatic ether; aromatic ketone; methyl ketone; monoamine; organofluorine compound; piperidines; tertiary amino compound | dopaminergic antagonist; second generation antipsychotic; serotonergic antagonist |
| fluphenacur | [no description available] | low | 0 | 0 | aromatic ether; benzoylurea insecticide; dichlorobenzene; N-acylurea; organofluorine compound | |
| nucleocidin | [no description available] | low | 0 | 0 | 6-aminopurines; adenosines; diol; organofluorine compound; sulfamate ester | antibacterial agent; bacterial metabolite; nucleoside antibiotic; protein synthesis inhibitor; trypanocidal drug |
| fluoroacetaldehyde | [no description available] | low | 0 | 0 | aldehyde; organofluorine compound | cardiotoxic agent |
| fc 75 | [no description available] | low | 0 | 0 | alkyltetrahydrofuran; organofluorine compound | |
| tetraconazole | [no description available] | low | 0 | 0 | dichlorobenzene; ether; organofluorine compound; triazoles | |
| hei 712 | [no description available] | low | 0 | 0 | organofluorine compound; quinolone | |
| n-(2,4-dichloro-5-(4-(difluoromethyl)-4,5-dihydro-3-methyl-5-oxo-1h-1,2,4-triazol-1-yl)phenyl)methanesulfonamide | [no description available] | low | 0 | 0 | dichlorobenzene; organofluorine compound; sulfonamide; triazoles | agrochemical; EC 1.3.3.4 (protoporphyrinogen oxidase) inhibitor; herbicide |
| thifluzamide | [no description available] | low | 0 | 0 | 1,3-thiazoles; anilide fungicide; aromatic amide; aromatic ether; dibromobenzene; organofluorine compound | antifungal agrochemical; EC 1.3.5.1 [succinate dehydrogenase (quinone)] inhibitor |
| fludioxonil | [no description available] | low | 0 | 0 | benzodioxoles; nitrile; organofluorine compound; pyrroles | androgen antagonist; antifungal agrochemical; estrogen receptor agonist |
| fluquinconazole | [no description available] | low | 0 | 0 | conazole fungicide; dichlorobenzene; organofluorine compound; quinazolines; triazole fungicide; triazoles | antifungal agrochemical; EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor |
| cloransulam-methyl | [no description available] | low | 0 | 0 | methyl ester; monochlorobenzenes; organofluorine compound; sulfonamide; triazolopyrimidines | agrochemical; EC 2.2.1.6 (acetolactate synthase) inhibitor; herbicide |
| fluazifop | [no description available] | low | 0 | 0 | aromatic ether; monocarboxylic acid; organofluorine compound; pyridines | |
| dithiopyr | [no description available] | low | 0 | 0 | organofluorine compound; pyridines; thioester | |
| s 53482 | [no description available] | low | 0 | 0 | benzoxazine; dicarboximide; organofluorine compound; terminal acetylenic compound | agrochemical; EC 1.3.3.4 (protoporphyrinogen oxidase) inhibitor; herbicide; teratogenic agent |
| clodinafop-propargyl | [no description available] | low | 0 | 0 | aromatic ether; carboxylic ester; organochlorine compound; organofluorine compound; propyzamide; pyridines | agrochemical; EC 6.4.1.2 (acetyl-CoA carboxylase) inhibitor; herbicide |
| triflusulfuron-methyl | [no description available] | low | 0 | 0 | 1,3,5-triazines; aromatic ether; benzoate ester; methyl ester; N-sulfonylurea; organofluorine compound; tertiary amino compound | agrochemical; EC 2.2.1.6 (acetolactate synthase) inhibitor; proherbicide |
| novaluron | [no description available] | low | 0 | 0 | aromatic ether; benzoylurea insecticide; monochlorobenzenes; organofluorine compound | |
| fulvestrant | [no description available] | low | 0 | 0 | 17beta-hydroxy steroid; 3-hydroxy steroid; organofluorine compound; sulfoxide | antineoplastic agent; estrogen antagonist; estrogen receptor antagonist |
| cyfluthrin | [no description available] | low | 0 | 0 | aromatic ether; cyclopropanecarboxylate ester; nitrile; organochlorine compound; organofluorine compound | agrochemical; pyrethroid ester insecticide |
| fluoromethyl 2,2-difluoro-1-(trifluoromethyl)vinyl ether | [no description available] | low | 0 | 0 | organofluorine compound | |
| florfenicol | [no description available] | low | 0 | 0 | organochlorine compound; organofluorine compound; secondary alcohol; secondary carboxamide; sulfone | antimicrobial agent |
| paliperidone | [no description available] | low | 0 | 0 | 1,2-benzoxazoles; heteroarylpiperidine; organofluorine compound; pyridopyrimidine; secondary alcohol | |
| sc 58125 | [no description available] | low | 0 | 0 | organofluorine compound; pyrazoles; sulfone | antineoplastic agent; cyclooxygenase 2 inhibitor |
| clofarabine | [no description available] | low | 0 | 0 | adenosines; organofluorine compound | antimetabolite; antineoplastic agent |
| 5-fluoromethylornithine | [no description available] | low | 0 | 0 | organofluorine compound; ornithine derivative | EC 2.6.1.13 (ornithine aminotransferase) inhibitor |
| nitroflurbiprofen | [no description available] | low | 0 | 0 | biphenyls; carboxylic ester; nitrate ester; organofluorine compound | cyclooxygenase 1 inhibitor; cyclooxygenase 2 inhibitor; EC 1.14.13.39 (nitric oxide synthase) inhibitor; geroprotector; non-steroidal anti-inflammatory drug; vasodilator agent |
| ezogabine | [no description available] | low | 0 | 0 | carbamate ester; organofluorine compound; secondary amino compound; substituted aniline | anticonvulsant; potassium channel modulator |
| garenoxacin | [no description available] | low | 0 | 0 | aromatic ether; cyclopropanes; isoindoles; organofluorine compound; quinolinemonocarboxylic acid; quinolone antibiotic | antibacterial drug; non-steroidal anti-inflammatory drug |
| 5-fluorowillardiine | [no description available] | low | 0 | 0 | L-alanine derivative; non-proteinogenic L-alpha-amino acid; organofluorine compound | AMPA receptor agonist |
| perfluoro-n-methyldecahydroisoquinoline | [no description available] | low | 0 | 0 | organofluorine compound | blood substitute |
| fc 80 | [no description available] | low | 0 | 0 | alkyltetrahydrofuran; organofluorine compound | |
| ezetimibe | [no description available] | low | 0 | 0 | azetidines; beta-lactam; organofluorine compound | anticholesteremic drug; antilipemic drug; antimetabolite |
| 5-fluorouridine 5'-phosphate | [no description available] | low | 0 | 0 | organofluorine compound; pyrimidine ribonucleoside 5'-monophosphate | drug metabolite |
| cox 189 | [no description available] | low | 0 | 0 | amino acid; monocarboxylic acid; organochlorine compound; organofluorine compound; secondary amino compound | cyclooxygenase 2 inhibitor; non-steroidal anti-inflammatory drug |
| canertinib | [no description available] | low | 0 | 0 | monochlorobenzenes; morpholines; organofluorine compound; quinazolines | antineoplastic agent; tyrosine kinase inhibitor |
| jte 522 | [no description available] | low | 0 | 0 | 1,3-oxazoles; organofluorine compound; sulfonamide | cyclooxygenase 2 inhibitor |
| trifluoromethionine | [no description available] | low | 0 | 0 | L-methionine derivative; non-proteinogenic L-alpha-amino acid; organofluorine compound | |
| lapatinib | [no description available] | low | 0 | 0 | furans; organochlorine compound; organofluorine compound; quinazolines | antineoplastic agent; tyrosine kinase inhibitor |
| cimicoxib | [no description available] | low | 0 | 0 | aromatic ether; imidazoles; organochlorine compound; organofluorine compound; sulfonamide | cyclooxygenase 2 inhibitor; non-steroidal anti-inflammatory drug |
| diflomotecan | [no description available] | low | 0 | 0 | epsilon-lactone; organic heteropentacyclic compound; organofluorine compound; organonitrogen heterocyclic compound; tertiary alcohol | antineoplastic agent; EC 5.99.1.2 (DNA topoisomerase) inhibitor |
| 5',5',5'-trifluoroleucine | [no description available] | low | 0 | 0 | leucine derivative; non-proteinogenic alpha-amino acid; organofluorine compound | |
| sorbinil | [no description available] | low | 0 | 0 | azaspiro compound; chromanes; imidazolidinone; organofluorine compound; oxaspiro compound | antioxidant; EC 1.1.1.21 (aldehyde reductase) inhibitor |
| linezolid | [no description available] | low | 0 | 0 | acetamides; morpholines; organofluorine compound; oxazolidinone | antibacterial drug; protein synthesis inhibitor |
| 2'-deoxy-2-fluoroadenosine | [no description available] | low | 0 | 0 | adenosines; organofluorine compound | |
| 8-(2-chloro-3,4,5-trimethoxybenzyl)-2-fluoro-9-pent-4-yn-1-yl-9H-purin-6-amine | [no description available] | low | 0 | 0 | 6-aminopurines; acetylenic compound; methoxybenzenes; monochlorobenzenes; organofluorine compound | antineoplastic agent; Hsp90 inhibitor |
| roflumilast | [no description available] | low | 0 | 0 | aromatic ether; benzamides; chloropyridine; cyclopropanes; organofluorine compound | anti-asthmatic drug; phosphodiesterase IV inhibitor |
| posaconazole | [no description available] | low | 0 | 0 | aromatic ether; conazole antifungal drug; N-arylpiperazine; organofluorine compound; oxolanes; triazole antifungal drug; triazoles | trypanocidal drug |
| efinaconazole | [no description available] | low | 0 | 0 | conazole antifungal drug; olefinic compound; organofluorine compound; piperidines; tertiary alcohol; tertiary amino compound; triazole antifungal drug | EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor |
| favipiravir | [no description available] | low | 0 | 0 | hydroxypyrazine; organofluorine compound; primary carboxamide | anticoronaviral agent; antiviral drug; EC 2.7.7.48 (RNA-directed RNA polymerase) inhibitor |
| 2-(3-Chloro-2-fluorophenyl)-2,3-dihydroisothiazol-3-one | [no description available] | low | 0 | 0 | organofluorine compound | |
| 4-[(3-fluorophenyl)methyl-(3-pyridinylmethyl)amino]-4-oxobutanoic acid | [no description available] | low | 0 | 0 | organofluorine compound | |
| transfluthrin | [no description available] | low | 0 | 0 | carboxylic ester; cyclopropanes; organochlorine compound; organofluorine compound | pyrethroid ester insecticide |
| 4-(4-fluorophenyl)-3H-thiazole-2-thione | [no description available] | low | 0 | 0 | organofluorine compound | |
| 2-(4-chlorophenyl)-5-(4-fluorophenyl)-1,3,4-oxadiazole | [no description available] | low | 0 | 0 | organofluorine compound | |
| N-[(4-fluorophenyl)methyl]-2-thiophen-2-ylacetamide | [no description available] | low | 0 | 0 | organofluorine compound | |
| 1-(cycloheptylideneamino)-3-(4-fluorophenyl)thiourea | [no description available] | low | 0 | 0 | organofluorine compound | |
| 2-(2-fluorophenyl)-5-phenyl-4-thieno[2,3-d][1,3]oxazinone | [no description available] | low | 0 | 0 | organofluorine compound | |
| sulindac | [no description available] | low | 0 | 0 | monocarboxylic acid; organofluorine compound; sulfoxide | analgesic; antineoplastic agent; antipyretic; apoptosis inducer; EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor; non-narcotic analgesic; non-steroidal anti-inflammatory drug; prodrug; tocolytic agent |
| N-cyano-N'-(2-fluorophenyl)carbamimidothioic acid [2-(tert-butylamino)-2-oxoethyl] ester | [no description available] | low | 0 | 0 | organofluorine compound | |
| N-(4-fluorobenzyl)urea | [no description available] | low | 0 | 0 | organofluorine compound | |
| N1-(3-chloro-4-fluorophenyl)-2-(methylthio)acetamide | [no description available] | low | 0 | 0 | organofluorine compound | |
| ethyl 1-[4-(4-chlorobenzenesulfonamido)phenyl]-5-(trifluoromethyl)pyrazole-4-carboxylate | [no description available] | low | 0 | 0 | ethyl ester; monochlorobenzenes; organofluorine compound; pyrazoles; sulfonamide | |
| S-[5-(trifluoromethyl)-4H-1,2,4-triazol-3-yl] 5-(phenylethynyl)furan-2-carbothioate | [no description available] | low | 0 | 0 | acetylenic compound; furans; organofluorine compound; thioester; triazoles | |
| 4-[1-(4-fluorophenyl)ethyl]-3-thiophen-2-yl-1H-1,2,4-triazole-5-thione | [no description available] | low | 0 | 0 | organofluorine compound | |
| 1-(4-fluorophenyl)-1-cyclopentanecarboxylic acid [2-(2,6-dimethyl-4-morpholinyl)-2-oxoethyl] ester | [no description available] | low | 0 | 0 | organofluorine compound | |
| deracoxib | [no description available] | low | 0 | 0 | organofluorine compound; pyrazoles; sulfonamide | cyclooxygenase 2 inhibitor; non-narcotic analgesic; non-steroidal anti-inflammatory drug |
| zd 6474 | [no description available] | low | 0 | 0 | aromatic ether; organobromine compound; organofluorine compound; piperidines; quinazolines; secondary amine | antineoplastic agent; tyrosine kinase inhibitor |
| 6,8-difluoro-4-(pyridin-3-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline | [no description available] | low | 0 | 0 | organic heterotricyclic compound; organofluorine compound; pyridines; secondary amino compound | |
| 1-(4-fluorophenyl)-N-methyl-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazine-2-carbothioamide | [no description available] | low | 0 | 0 | organofluorine compound | |
| 2-[[2-[3-(4-fluorophenyl)-5-thiophen-2-yl-3,4-dihydropyrazol-2-yl]-2-oxoethyl]thio]acetic acid butyl ester | [no description available] | low | 0 | 0 | organofluorine compound | |
| sc 560 | [no description available] | low | 0 | 0 | aromatic ether; monochlorobenzenes; organofluorine compound; pyrazoles | angiogenesis modulating agent; antineoplastic agent; apoptosis inducer; cyclooxygenase 1 inhibitor; non-steroidal anti-inflammatory drug |
| 1-[(2-fluorophenyl)methyl]-4-pyrazolamine | [no description available] | low | 0 | 0 | organofluorine compound | |
| 3-[2,2-dichloro-1-(3-fluoro-4-methylphenyl)ethyl]-1,1-bis(phenylmethyl)urea | [no description available] | low | 0 | 0 | organofluorine compound | |
| jtk-303 | [no description available] | low | 0 | 0 | aromatic ether; monochlorobenzenes; organofluorine compound; quinolinemonocarboxylic acid; quinolone | HIV-1 integrase inhibitor |
| arachidonyltrifluoromethane | [no description available] | low | 0 | 0 | fatty acid derivative; ketone; olefinic compound; organofluorine compound | EC 3.1.1.4 (phospholipase A2) inhibitor |
| cyhalothrin | [no description available] | low | 0 | 0 | aromatic ether; cyclopropanecarboxylate ester; nitrile; organochlorine compound; organofluorine compound | agrochemical; pyrethroid ester acaricide; pyrethroid ester insecticide |
| sulindac sulfide | [no description available] | low | 0 | 0 | aryl sulfide; monocarboxylic acid; organofluorine compound | antineoplastic agent; apoptosis inducer; non-steroidal anti-inflammatory drug |
| bw b70c | [no description available] | low | 0 | 0 | aromatic ether; hydroxamic acid; organofluorine compound; ureas | EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor |
| sulindac sulfone | [no description available] | low | 0 | 0 | monocarboxylic acid; organofluorine compound; sulfone | apoptosis inducer; cyclooxygenase 2 inhibitor; EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor |
| clodinafop | [no description available] | low | 0 | 0 | aromatic ether; monocarboxylic acid; organochlorine compound; organofluorine compound; pyridines | EC 6.4.1.2 (acetyl-CoA carboxylase) inhibitor; phenoxy herbicide |
| 2-tert-butyl-9-fluoro-3,6-dihydro-7h-benz(h)imidazo(4,5-f)isoquinoline-7-one | [no description available] | low | 0 | 0 | organic heterotetracyclic compound; organofluorine compound | EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor |
| z-val-ala-asp(ome)-fluoromethylketone | [no description available] | low | 0 | 0 | carbamate ester; organofluorine compound; tripeptide | apoptosis inhibitor; protease inhibitor |
| robenacoxib | [no description available] | low | 0 | 0 | aromatic amino acid; monocarboxylic acid; organofluorine compound; phenylacetic acids; secondary amino compound | cyclooxygenase 2 inhibitor; non-narcotic analgesic; non-steroidal anti-inflammatory drug |
| acrinathrin | [no description available] | low | 0 | 0 | cyclopropanecarboxylate ester; organofluorine compound | pyrethroid ester acaricide; pyrethroid ester insecticide |
| bifenthrin | [no description available] | low | 0 | 0 | carboxylic ester; cyclopropanecarboxylate ester; cyclopropanes; organochlorine compound; organofluorine compound | pyrethroid ester acaricide; pyrethroid ester insecticide |
| netupitant | [no description available] | low | 0 | 0 | aminopyridine; monocarboxylic acid amide; N-alkylpiperazine; N-arylpiperazine; organofluorine compound; toluenes | antiemetic; neurokinin-1 receptor antagonist |
| flibanserin | [no description available] | low | 0 | 0 | benzimidazoles; N-alkylpiperazine; N-arylpiperazine; organofluorine compound | antidepressant; serotonergic agonist; serotonergic antagonist |
| ru 58668 | [no description available] | low | 0 | 0 | 17beta-hydroxy steroid; 3-hydroxy steroid; aromatic ether; organofluorine compound; sulfone | anti-estrogen; antineoplastic agent; estrogen receptor antagonist |
| nepicastat | [no description available] | low | 0 | 0 | 1,3-dihydroimidazole-2-thiones; organofluorine compound; primary amino compound; tetralins | EC 1.14.17.1 (dopamine beta-monooxygenase) inhibitor |
| gw 501516 | [no description available] | low | 0 | 0 | 1,3-thiazoles; aromatic ether; aryl sulfide; monocarboxylic acid; organofluorine compound | carcinogenic agent; PPARbeta/delta agonist |
| noviflumuron | [no description available] | low | 0 | 0 | aromatic ether; benzoylurea insecticide; dichlorobenzene; organofluorine compound | |
| flonicamid | [no description available] | low | 0 | 0 | nitrile; organofluorine compound; pyridinecarboxamide | environmental contaminant; insecticide; xenobiotic |
| 4-(5-(4-fluorophenyl)-3-(trifluoromethyl)-1h-pyrazol-1-yl)benzenesulfonamide | [no description available] | low | 0 | 0 | organofluorine compound; pyrazoles; sulfonamide | cyclooxygenase 2 inhibitor; non-narcotic analgesic; non-steroidal anti-inflammatory drug |
| paliperidone palmitate | [no description available] | low | 0 | 0 | 1,2-benzoxazoles; fatty acid ester; heteroarylpiperidine; organofluorine compound; pyridopyrimidine | |
| cangrelor | [no description available] | low | 0 | 0 | adenosine 5'-phosphate; aryl sulfide; nucleoside triphosphate analogue; organochlorine compound; organofluorine compound; secondary amino compound | P2Y12 receptor antagonist; platelet aggregation inhibitor |
| tafluprost | [no description available] | low | 0 | 0 | isopropyl ester; organofluorine compound; prostaglandins Falpha | prostaglandin receptor agonist |
| ticagrelor | [no description available] | low | 0 | 0 | aryl sulfide; hydroxyether; organofluorine compound; secondary amino compound; triazolopyrimidines | P2Y12 receptor antagonist; platelet aggregation inhibitor |
| rucaparib | [no description available] | low | 0 | 0 | azepinoindole; caprolactams; organofluorine compound; secondary amino compound | antineoplastic agent; EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor |
| NNC 55-0396 (free base) | [no description available] | low | 0 | 0 | benzimidazoles; cyclopropanecarboxylate ester; organofluorine compound; tertiary amino compound; tetralins | angiogenesis inhibitor; antineoplastic agent; apoptosis inducer; neuroprotective agent; potassium channel blocker; T-type calcium channel blocker |
| osu 03012 | [no description available] | low | 0 | 0 | antibiotic antifungal drug; aromatic amide; glycine derivative; organofluorine compound; phenanthrenes; pyrazoles | antineoplastic agent; apoptosis inducer; EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor |
| vorapaxar | [no description available] | low | 0 | 0 | carbamate ester; lactone; naphthofuran; organofluorine compound; pyridines | cardiovascular drug; platelet aggregation inhibitor; protease-activated receptor-1 antagonist |
| azd 6244 | [no description available] | low | 0 | 0 | benzimidazoles; bromobenzenes; hydroxamic acid ester; monochlorobenzenes; organofluorine compound; secondary amino compound | anticoronaviral agent; antineoplastic agent; EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor |
| bibw 2992 | [no description available] | low | 0 | 0 | aromatic ether; enamide; furans; monochlorobenzenes; organofluorine compound; quinazolines; secondary carboxamide; tertiary amino compound | antineoplastic agent; tyrosine kinase inhibitor |
| rolapitant | [no description available] | low | 0 | 0 | azaspiro compound; ether; organofluorine compound; piperidines; pyrrolidin-2-ones | antiemetic; neurokinin-1 receptor antagonist |
| r-138727 | [no description available] | low | 0 | 0 | organofluorine compound | |
| fluoxastrobin | [no description available] | low | 0 | 0 | aromatic ether; dioxazine; monochlorobenzenes; organofluorine compound; oxime O-ether; pyrimidines; strobilurin antifungal agent | antifungal agrochemical; mitochondrial cytochrome-bc1 complex inhibitor |
| flumorph | [no description available] | low | 0 | 0 | aromatic ether; enamide; morpholines; organofluorine compound; tertiary carboxamide | |
| fluopicolide | [no description available] | low | 0 | 0 | benzamide fungicide; benzamides; dichlorobenzene; monochloropyridine; organofluorine compound | antifungal agrochemical |
| gamendazole | [no description available] | low | 0 | 0 | alpha,beta-unsaturated monocarboxylic acid; dichlorobenzene; indazoles; olefinic compound; organofluorine compound | antispermatogenic agent; eukaryotic translation elongation factor 1alpha 1 inhibitor; Hsp90 inhibitor; synthetic oral contraceptive |
| tedizolid | [no description available] | low | 0 | 0 | carbamate ester; organofluorine compound; oxazolidinone; primary alcohol; pyridines; tetrazoles | antimicrobial agent; drug metabolite; protein synthesis inhibitor |
| rx-3117 | [no description available] | low | 0 | 0 | organofluorine compound; primary allylic alcohol; triol | antimetabolite; antineoplastic agent; apoptosis inducer; DNA synthesis inhibitor; prodrug |
| picoxystrobin | [no description available] | low | 0 | 0 | aromatic ether; enoate ester; enol ether; methoxyacrylate strobilurin antifungal agent; organofluorine compound; pyridines | antifungal agrochemical; mitochondrial cytochrome-bc1 complex inhibitor |
| bay 63-2521 | [no description available] | low | 0 | 0 | aminopyrimidine; carbamate ester; organofluorine compound; pyrazolopyridine | antihypertensive agent; soluble guanylate cyclase activator |
| penthiopyrad | [no description available] | low | 0 | 0 | aromatic amide; organofluorine compound; pyrazoles; thiophenes | |
| tedizolid phosphate | [no description available] | low | 0 | 0 | carbamate ester; organofluorine compound; oxazolidinone; phosphate monoester; pyridines; tetrazoles | antimicrobial agent; prodrug; protein synthesis inhibitor |
| tavaborole | [no description available] | low | 0 | 0 | benzoxaborole; organofluorine compound | antifungal agent; EC 6.1.1.4 (leucine--tRNA ligase) inhibitor; protein synthesis inhibitor |
| tembotrione | [no description available] | low | 0 | 0 | aromatic ketone; beta-triketone; cyclic ketone; ether; monochlorobenzenes; organofluorine compound; sulfone | agrochemical; carotenoid biosynthesis inhibitor; EC 1.13.11.27 (4-hydroxyphenylpyruvate dioxygenase) inhibitor; herbicide |
| finafloxacin | [no description available] | low | 0 | 0 | cyclopropanes; monocarboxylic acid; nitrile; organofluorine compound; quinolone; secondary amino compound; tertiary amino compound | antibacterial drug; antimicrobial agent |
| 3-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(piperidin-4-yl)pyrazol-4-yl]pyridin-2-amine | [no description available] | low | 0 | 0 | aminopyridine; aromatic ether; dichlorobenzene; organofluorine compound; pyrazolylpiperidine; racemate | antineoplastic agent; biomarker; EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor |
| idelalisib | [no description available] | low | 0 | 0 | aromatic amine; organofluorine compound; purines; quinazolines; secondary amino compound | antineoplastic agent; apoptosis inducer; EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor |
| zstk474 | [no description available] | low | 0 | 0 | benzimidazoles; morpholines; organofluorine compound; triamino-1,3,5-triazine | antineoplastic agent; EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor |
| trifloxystrobin | [no description available] | low | 0 | 0 | methoxyiminoacetate strobilurin antifungal agent; methyl ester; organofluorine compound; oxime O-ether | antifungal agrochemical; mitochondrial cytochrome-bc1 complex inhibitor |
| 5-fluoro-1,3-dimethyl-N-[2-(4-methylpentan-2-yl)phenyl]pyrazole-4-carboxamide | [no description available] | low | 0 | 0 | aromatic amide; organofluorine compound; pyrazoles | |
| n-(2-(1,1'-bicyclopropyl)-2-ylphenyl)-3-(difluoromethyl)-1-methyl-1h-pyrazole-4-carboxamide | [no description available] | low | 0 | 0 | aromatic amide; cyclopropanes; organofluorine compound; pyrazoles; ring assembly | |
| trametinib | [no description available] | low | 0 | 0 | acetamides; aromatic amine; cyclopropanes; organofluorine compound; organoiodine compound; pyridopyrimidine; ring assembly | anticoronaviral agent; antineoplastic agent; EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor; geroprotector |
| butafenacil | [no description available] | low | 0 | 0 | benzoate ester; diester; monochlorobenzenes; olefinic compound; organofluorine compound | EC 1.3.3.4 (protoporphyrinogen oxidase) inhibitor; herbicide |
| bgt226 | [no description available] | low | 0 | 0 | aromatic ether; imidazoquinoline; N-arylpiperazine; organofluorine compound; pyridines | antineoplastic agent; EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor; mTOR inhibitor |
| buparlisib | [no description available] | low | 0 | 0 | aminopyridine; aminopyrimidine; morpholines; organofluorine compound | antineoplastic agent; EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor |
| lumacaftor | [no description available] | low | 0 | 0 | aromatic amide; benzodioxoles; benzoic acids; cyclopropanes; organofluorine compound; pyridines | CFTR potentiator; orphan drug |
| ro5126766 | [no description available] | low | 0 | 0 | aryloxypyrimidine; coumarins; organofluorine compound; pyridines; sulfamides | antineoplastic agent; EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor |
| sulfoxaflor | [no description available] | low | 0 | 0 | nitrile; organofluorine compound; pyridines; sulfoximide | |
| azd 7545 | [no description available] | low | 0 | 0 | benzamides; monochlorobenzenes; organofluorine compound; secondary carboxamide; sulfone; tertiary alcohol; tertiary carboxamide | EC 2.7.11.2 - [pyruvate dehydrogenase (acetyl-transferring)] kinase inhibitor; hypoglycemic agent |
| ph 797804 | [no description available] | low | 0 | 0 | aromatic ether; benzamides; organobromine compound; organofluorine compound; pyridone | anti-inflammatory agent; EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor |
| lde225 | [no description available] | low | 0 | 0 | aminopyridine; aromatic ether; benzamides; biphenyls; morpholines; organofluorine compound; tertiary amino compound | antineoplastic agent; Hedgehog signaling pathway inhibitor; SMO receptor antagonist |
| dafadine D | [no description available] | low | 0 | 0 | aromatic amide; aromatic ether; isoxazoles; N-acylpiperidine; organofluorine compound; pyridines | P450 inhibitor |
| canagliflozin | [no description available] | low | 0 | 0 | C-glycosyl compound; organofluorine compound; thiophenes | hypoglycemic agent; sodium-glucose transport protein subtype 2 inhibitor |
| florbetapir f 18 | [no description available] | low | 0 | 0 | (18)F radiopharmaceutical; aromatic ether; organofluorine compound; pyridines; substituted aniline | radioactive imaging agent |
| navitoclax | [no description available] | low | 0 | 0 | aryl sulfide; monochlorobenzenes; morpholines; N-sulfonylcarboxamide; organofluorine compound; piperazines; secondary amino compound; sulfone; tertiary amino compound | antineoplastic agent; apoptosis inducer; B-cell lymphoma 2 inhibitor |
| dcc-2036 | [no description available] | low | 0 | 0 | organofluorine compound; phenylureas; pyrazoles; pyridinecarboxamide; quinolines | tyrosine kinase inhibitor |
| cabozantinib | [no description available] | low | 0 | 0 | aromatic ether; dicarboxylic acid diamide; organofluorine compound; quinolines | antineoplastic agent; tyrosine kinase inhibitor |
| pexidartinib | [no description available] | low | 0 | 0 | aminopyridine; organochlorine compound; organofluorine compound; pyrrolopyridine; secondary amino compound | antineoplastic agent; EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor |
| TAK-580 | [no description available] | low | 0 | 0 | 1,3-thiazolecarboxamide; aminopyrimidine; chloropyridine; organofluorine compound; pyrimidinecarboxamide; secondary carboxamide | antineoplastic agent; apoptosis inducer; B-Raf inhibitor |
| dabrafenib | [no description available] | low | 0 | 0 | 1,3-thiazoles; aminopyrimidine; organofluorine compound; sulfonamide | anticoronaviral agent; antineoplastic agent; B-Raf inhibitor |
| sofosbuvir | [no description available] | low | 0 | 0 | isopropyl ester; L-alanyl ester; nucleotide conjugate; organofluorine compound; phosphoramidate ester | antiviral drug; hepatitis C protease inhibitor; prodrug |
| [5-fluoro-1-(4-isopropylbenzylidene)-2-methylinden-3-yl]acetic acid | [no description available] | low | 0 | 0 | organofluorine compound | non-steroidal anti-inflammatory drug |
| torin 1 | [no description available] | low | 0 | 0 | N-acylpiperazine; N-arylpiperazine; organofluorine compound; pyridoquinoline; quinolines | antineoplastic agent; mTOR inhibitor |
| ro 4929097 | [no description available] | low | 0 | 0 | dibenzoazepine; dicarboxylic acid diamide; lactam; organofluorine compound | EC 3.4.23.46 (memapsin 2) inhibitor |
| torin 2 | [no description available] | low | 0 | 0 | aminopyridine; organofluorine compound; primary amino compound; pyridoquinoline | antineoplastic agent; mTOR inhibitor |
| N-[9-(dichloromethylene)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-3-(difluoromethyl)-1-methylpyrazole-4-carboxamide | [no description available] | low | 0 | 0 | aromatic amide; bridged compound; olefinic compound; organochlorine compound; organofluorine compound; pyrazoles | |
| vericiguat | [no description available] | low | 0 | 0 | aminopyrimidine; carbamate ester; organofluorine compound; pyrazolopyridine | antihypertensive agent; soluble guanylate cyclase activator; vasodilator agent |
| pacific blue succinimidyl ester | [no description available] | low | 0 | 0 | hydroxycoumarin; N-hydroxysuccinimide ester; organofluorine compound | fluorochrome |
| 3-(difluoromethyl)-N-methoxy-1-methyl-N-[1-(2,4,6-trichlorophenyl)propan-2-yl]pyrazole-4-carboxamide | [no description available] | low | 0 | 0 | aromatic amide; monocarboxylic acid amide; organofluorine compound; pyrazoles; trichlorobenzene | |
| oxathiapiprolin | [no description available] | low | 0 | 0 | 1,3-thiazoles; isoxazoline; N-acylpiperidine; organofluorine compound; pyrazoles; tertiary carboxamide | |
| 5-[[5-(4-fluoro-2-hydroxyphenyl)-2-furanyl]methylidene]thiazolidine-2,4-dione | [no description available] | low | 0 | 0 | halophenol; organofluorine compound | |
| LimKi 3 | [no description available] | low | 0 | 0 | 1,3-thiazoles; dichlorobenzene; organofluorine compound; pyrazoles; secondary carboxamide | LIM kinase inhibitor |
| ledipasvir | [no description available] | low | 0 | 0 | azaspiro compound; benzimidazole; bridged compound; carbamate ester; carboxamide; fluorenes; imidazoles; L-valine derivative; N-acylpyrrolidine; organofluorine compound | antiviral drug; hepatitis C protease inhibitor |
| ivosidenib | [no description available] | low | 0 | 0 | cyanopyridine; monochlorobenzenes; organofluorine compound; pyrrolidin-2-ones; secondary carboxamide; tertiary carboxamide | antineoplastic agent; EC 1.1.1.42 (isocitrate dehydrogenase) inhibitor |
| as 1842856 | [no description available] | low | 0 | 0 | organofluorine compound; primary amino compound; quinolinemonocarboxylic acid; quinolone; secondary amino compound; tertiary amino compound | anti-obesity agent; antineoplastic agent; apoptosis inducer; autophagy inhibitor; forkhead box protein O1 inhibitor; hypoglycemic agent |
| praliciguat | [no description available] | low | 0 | 0 | aminopyrimidine; isoxazoles; monofluorobenzenes; organofluorine compound; pyrazoles; secondary amino compound; tertiary alcohol | anti-inflammatory agent; antihypertensive agent; soluble guanylate cyclase activator; vasodilator agent |
| enasidenib | [no description available] | low | 0 | 0 | 1,3,5-triazines; aminopyridine; aromatic amine; organofluorine compound; secondary amino compound; tertiary alcohol | antineoplastic agent; EC 1.1.1.42 (isocitrate dehydrogenase) inhibitor |
| MMP-9-IN-1 | [no description available] | low | 0 | 0 | aromatic compound; organic sulfide; organofluorine compound; pyrimidone; secondary carboxamide | antineoplastic agent; EC 3.4.24.35 (gelatinase B) inhibitor |
| 5-(2,5-difluorophenyl)-N-(2-oxolanylmethyl)-6H-1,3,4-thiadiazin-2-amine | [no description available] | low | 0 | 0 | organofluorine compound | |
| nirmatrelvir | [no description available] | low | 0 | 0 | azabicyclohexane; nitrile; organofluorine compound; pyrrolidin-2-ones; pyrrolidinecarboxamide; secondary carboxamide; tertiary carboxamide | anticoronaviral agent; EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor |
| 3-aminobenzamide | [no description available] | low | 0 | 0 | benzamides; substituted aniline | EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor |
| dan 2163 | [no description available] | low | 0 | 0 | aromatic amide; aromatic amine; benzamides; pyrrolidines; sulfone | environmental contaminant; second generation antipsychotic; xenobiotic |
| benzamide | [no description available] | low | 0 | 0 | benzamides | |
| bromopride | [no description available] | low | 0 | 0 | benzamides | |
| ci 994 | [no description available] | low | 0 | 0 | acetamides; benzamides; substituted aniline | antineoplastic agent; EC 3.5.1.98 (histone deacetylase) inhibitor |
| cisapride | [no description available] | low | 0 | 0 | benzamides | |
| 2-hexyloxybenzamide | [no description available] | low | 0 | 0 | aromatic ether; benzamides | antifungal agent |
| itopride | [no description available] | low | 0 | 0 | benzamides | |
| labetalol | [no description available] | low | 0 | 0 | benzamides; benzenes; phenols; primary carboxamide; salicylamides; secondary alcohol; secondary amino compound | |
| lorglumide | [no description available] | low | 0 | 0 | benzamides; dicarboxylic acid monoamide; dichlorobenzene; glutamic acid derivative | |
| 4-(dimethylamino)-n-(7-(hydroxyamino)-7-oxoheptyl)benzamide | [no description available] | low | 0 | 0 | benzamides; hydroxamic acid; secondary carboxamide; tertiary amino compound | antineoplastic agent; apoptosis inducer; EC 3.5.1.98 (histone deacetylase) inhibitor |
| metoclopramide | [no description available] | low | 0 | 0 | benzamides; monochlorobenzenes; substituted aniline; tertiary amino compound | antiemetic; dopaminergic antagonist; environmental contaminant; gastrointestinal drug; xenobiotic |
| moclobemide | [no description available] | low | 0 | 0 | benzamides; monochlorobenzenes; morpholines | antidepressant; environmental contaminant; xenobiotic |
| entinostat | [no description available] | low | 0 | 0 | benzamides; carbamate ester; primary amino compound; pyridines; substituted aniline | antineoplastic agent; apoptosis inducer; EC 3.5.1.98 (histone deacetylase) inhibitor |
| deet | [no description available] | low | 0 | 0 | benzamides; monocarboxylic acid amide | environmental contaminant; insect repellent; xenobiotic |
| acecainide | [no description available] | low | 0 | 0 | acetamides; benzamides | anti-arrhythmia drug |
| nemonapride | [no description available] | low | 0 | 0 | benzamides; monochlorobenzenes; monomethoxybenzene; N-alkylpyrrolidine; secondary amino compound; secondary carboxamide; substituted aniline | |
| niclosamide | [no description available] | low | 0 | 0 | benzamides; C-nitro compound; monochlorobenzenes; salicylanilides; secondary carboxamide | anthelminthic drug; anticoronaviral agent; antiparasitic agent; apoptosis inducer; molluscicide; piscicide; STAT3 inhibitor |
| picotamide | [no description available] | low | 0 | 0 | benzamides | |
| procainamide | [no description available] | low | 0 | 0 | benzamides | anti-arrhythmia drug; platelet aggregation inhibitor; sodium channel blocker |
| procarbazine | [no description available] | low | 0 | 0 | benzamides; hydrazines | antineoplastic agent |
| proglumetacin | [no description available] | low | 0 | 0 | aromatic ether; benzamides; carboxylic ester; monochlorobenzenes; N-acylindole; N-alkylpiperazine | antipyretic; EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor; lipoxygenase inhibitor; non-narcotic analgesic; non-steroidal anti-inflammatory drug; prodrug |
| proglumide | [no description available] | low | 0 | 0 | benzamides; dicarboxylic acid monoamide; glutamine derivative; racemate | anti-ulcer drug; cholecystokinin antagonist; cholinergic antagonist; delta-opioid receptor agonist; drug metabolite; gastrointestinal drug; opioid analgesic; xenobiotic metabolite |
| imatinib | [no description available] | low | 0 | 0 | aromatic amine; benzamides; N-methylpiperazine; pyridines; pyrimidines | antineoplastic agent; apoptosis inducer; tyrosine kinase inhibitor |
| sulpiride | [no description available] | low | 0 | 0 | benzamides; N-alkylpyrrolidine; sulfonamide | antidepressant; antiemetic; antipsychotic agent; dopaminergic antagonist |
| tiapride | [no description available] | low | 0 | 0 | benzamides | |
| trimethobenzamide | [no description available] | low | 0 | 0 | benzamides; tertiary amino compound | antiemetic |
| troxipide | [no description available] | low | 0 | 0 | benzamides | |
| zm 336372 | [no description available] | low | 0 | 0 | benzamides | |
| iodohippuric acid | [no description available] | low | 0 | 0 | benzamides; N-acylglycine; organoiodine compound | |
| benzoylarginine-2-naphthylamide | [no description available] | low | 0 | 0 | arginine derivative; benzamides; N-(2-naphthyl)carboxamide | |
| 4-(benzoylamino)-2-hydroxybenzoic acid | [no description available] | low | 0 | 0 | benzamides | |
| ameltolide | [no description available] | low | 0 | 0 | benzamides | |
| antimycin a | [no description available] | low | 0 | 0 | benzamides; formamides; macrodiolide; phenols | antifungal agent; mitochondrial respiratory-chain inhibitor; piscicide |
| rebemide | [no description available] | low | 0 | 0 | benzamides | |
| 2,6-dichlorobenzamide | [no description available] | low | 0 | 0 | benzamides; dichlorobenzene | herbicide; marine xenobiotic metabolite |
| fluorophene | [no description available] | low | 0 | 0 | benzamides | |
| 2-toluanilide | [no description available] | low | 0 | 0 | benzamides; benzanilide fungicide | |
| 2-bromo-N-phenylbenzamide | [no description available] | low | 0 | 0 | benzamides | |
| xipamide | [no description available] | low | 0 | 0 | benzamides | |
| capobenic acid | [no description available] | low | 0 | 0 | benzamides | |
| pronamide | [no description available] | low | 0 | 0 | benzamides; dichlorobenzene; terminal acetylenic compound | agrochemical; herbicide |
| clanobutin | [no description available] | low | 0 | 0 | benzamides | |
| nitazoxanide | [no description available] | low | 0 | 0 | benzamides; carboxylic ester | |
| Flamprop | [no description available] | low | 0 | 0 | benzamides | |
| N-[4-(dimethylamino)phenyl]-3,4,5-trimethoxybenzamide | [no description available] | low | 0 | 0 | benzamides | |
| endralazine | [no description available] | low | 0 | 0 | benzamides | |
| flutolanil | [no description available] | low | 0 | 0 | (trifluoromethyl)benzenes; aromatic ether; benzamides; benzanilide fungicide | antifungal agrochemical; EC 1.3.5.1 [succinate dehydrogenase (quinone)] inhibitor |
| encainide | [no description available] | low | 0 | 0 | benzamides; piperidines | anti-arrhythmia drug; sodium channel blocker |
| nelfinavir | [no description available] | low | 0 | 0 | aryl sulfide; benzamides; organic heterobicyclic compound; phenols; secondary alcohol; tertiary amino compound | antineoplastic agent; HIV protease inhibitor |
| n-benzoylpiperidine | [no description available] | low | 0 | 0 | benzamides; N-acylpiperidine | |
| pancopride | [no description available] | low | 0 | 0 | benzamides | |
| octylonium | [no description available] | low | 0 | 0 | benzamides | |
| parsalmide | [no description available] | low | 0 | 0 | benzamides | |
| isoxaben | [no description available] | low | 0 | 0 | benzamides; isoxazoles | cellulose synthesis inhibitor; herbicide |
| 4-aminobenzamide | [no description available] | low | 0 | 0 | benzamides | |
| 4-Methoxybenzamide | [no description available] | low | 0 | 0 | benzamides | |
| benzoyltyrosine ethyl ester | [no description available] | low | 0 | 0 | benzamides; ethyl ester; L-tyrosine derivative; phenols | chromogenic compound |
| salifungin | [no description available] | low | 0 | 0 | benzamides | |
| n-benzoyl-l-arginine | [no description available] | low | 0 | 0 | benzamides; N-acyl-L-arginine | |
| gr 127935 | [no description available] | low | 0 | 0 | 1,2,4-oxadiazole; benzamides; N-alkylpiperazine; N-arylpiperazine | |
| zacopride | [no description available] | low | 0 | 0 | benzamides | |
| mozavaptan | [no description available] | low | 0 | 0 | benzamides | aquaretic |
| mosapride | [no description available] | low | 0 | 0 | aromatic ether; benzamides; monochlorobenzenes; monofluorobenzenes; morpholines; secondary carboxamide; substituted aniline; tertiary amino compound | |
| zoxamide | [no description available] | low | 0 | 0 | alpha-chloroketone; benzamides; dichlorobenzene | |
| procainamide 4-hydroxylamine | [no description available] | low | 0 | 0 | benzamides; hydroxylamines | drug metabolite |
| ly 188544 | [no description available] | low | 0 | 0 | benzamides | |
| gr 55562 | [no description available] | low | 0 | 0 | benzamides | |
| n-(2,6-dimethylphenyl)-4-(((diethylamino)acetyl)amino)benzamide | [no description available] | low | 0 | 0 | benzamides | |
| tariquidar | [no description available] | low | 0 | 0 | benzamides | |
| n-benzoyltyrosine | [no description available] | low | 0 | 0 | benzamides; N-acyl-L-tyrosine | |
| rp 73401 | [no description available] | low | 0 | 0 | aromatic ether; benzamides; chloropyridine; monocarboxylic acid amide | anti-asthmatic drug; anti-inflammatory agent; bronchodilator agent; phosphodiesterase IV inhibitor |
| brovanexine | [no description available] | low | 0 | 0 | benzamides | |
| aminopotentidine | [no description available] | low | 0 | 0 | aromatic ether; benzamides; guanidines; nitrile; piperidines; substituted aniline | H2-receptor antagonist |
| asperphenamate | [no description available] | low | 0 | 0 | benzamides; carboxylic ester; L-phenylalanine derivative | antineoplastic agent |
| N-(3-fluorophenyl)benzamide | [no description available] | low | 0 | 0 | benzamides | |
| benzoylphenylalanine | [no description available] | low | 0 | 0 | benzamides; N-acyl-amino acid | |
| 2-methoxy-N-[2-(methylthio)phenyl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| 2-(4-fluorobenzoylamino)benzoic acid methyl ester | [no description available] | low | 0 | 0 | benzamides | |
| xv 638 | [no description available] | low | 0 | 0 | 1,3-thiazoles; benzamides; diazepanone; diol; secondary alcohol; secondary carboxamide; ureas | HIV protease inhibitor |
| 2-(3-benzamidophenoxy)acetic acid | [no description available] | low | 0 | 0 | benzamides | |
| gw9662 | [no description available] | low | 0 | 0 | benzamides | |
| N-[2-(1-cyclohexenyl)ethyl]-4-(4-morpholinylmethyl)benzamide | [no description available] | low | 0 | 0 | benzamides | |
| 2-methoxy-N-[6-(1-oxobutylamino)-3-pyridinyl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| N-[4-chloro-2-[(2,4-dimethoxyanilino)-oxomethyl]phenyl]-2-furancarboxamide | [no description available] | low | 0 | 0 | benzamides | |
| [3-[3-(5-methyl-2-furanyl)-1,2,4-oxadiazol-5-yl]-1-piperidinyl]-phenylmethanone | [no description available] | low | 0 | 0 | benzamides; N-acylpiperidine | |
| 4-methyl-N-[2-[4-(2-methyl-1-oxopropyl)-1-piperazinyl]phenyl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| N-[2-(2-ethyl-5-tetrazolyl)phenyl]-3-(1-tetrazolyl)benzamide | [no description available] | low | 0 | 0 | benzamides | |
| N-[2-(2-ethyl-5-tetrazolyl)phenyl]-4-(1-tetrazolyl)benzamide | [no description available] | low | 0 | 0 | benzamides | |
| N-[2,5-diethoxy-4-[[oxo-(3,4,5-trimethoxyphenyl)methyl]amino]phenyl]-2-furancarboxamide | [no description available] | low | 0 | 0 | benzamides | |
| (2,4-difluorophenyl)-[3-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]-1-piperidinyl]methanone | [no description available] | low | 0 | 0 | benzamides; N-acylpiperidine | |
| 2-ethoxy-N-[4-(4-morpholinylsulfonyl)phenyl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| 4-methyl-N-(2-methyl-5-tetrazolyl)benzamide | [no description available] | low | 0 | 0 | benzamides | |
| N-[2,5-dimethoxy-4-[[2-(4-morpholinyl)-1-oxoethyl]amino]phenyl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| N-(4-fluorophenyl)-4-(2-oxolanylmethylsulfamoyl)benzamide | [no description available] | low | 0 | 0 | benzamides | |
| azidopine | [no description available] | low | 0 | 0 | benzamides | |
| 4-methoxy-N1,N3-bis(3-pyridinyl)benzene-1,3-dicarboxamide | [no description available] | low | 0 | 0 | benzamides | |
| 2,3,4,5,6-pentafluoro-N-(phenylmethyl)benzamide | [no description available] | low | 0 | 0 | benzamides | |
| N-(1,1-dioxo-3-thiolanyl)-N-(thiophen-2-ylmethyl)benzamide | [no description available] | low | 0 | 0 | benzamides | |
| N-(3-methoxyphenyl)-2-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| 2-[[(4-acetyloxy-3-methoxyphenyl)-oxomethyl]amino]-5-hydroxybenzoic acid | [no description available] | low | 0 | 0 | benzamides | |
| N-(3-acetamidophenyl)-4-methoxybenzamide | [no description available] | low | 0 | 0 | benzamides | |
| N-(3-acetamidophenyl)-3-chlorobenzamide | [no description available] | low | 0 | 0 | benzamides | |
| 4-methoxy-N-(5-methyl-3-isoxazolyl)benzamide | [no description available] | low | 0 | 0 | benzamides | |
| 4-tert-butyl-N-[4-(4-morpholinyl)phenyl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| N-(2-fluorophenyl)-4-phenylmethoxybenzamide | [no description available] | low | 0 | 0 | benzamides | |
| 4-methyl-N-(5-methyl-1,3,4-thiadiazol-2-yl)benzamide | [no description available] | low | 0 | 0 | benzamides | |
| 4-methyl-N-[4-(4-morpholinyl)phenyl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| 4-methoxy-N-(3-pyridinylmethyl)benzamide | [no description available] | low | 0 | 0 | benzamides | |
| 2-methoxy-N-(2-pyridinyl)benzamide | [no description available] | low | 0 | 0 | benzamides | |
| N-[3-(4-oxo-3,1-benzoxazin-2-yl)phenyl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| N-[(4-pyrimidinylthio)methyl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| N-(5-ethyl-1,3,4-thiadiazol-2-yl)-3-methoxybenzamide | [no description available] | low | 0 | 0 | benzamides | |
| N-(4-acetamidophenyl)-2-bromobenzamide | [no description available] | low | 0 | 0 | benzamides | |
| N-(5-acetyl-4-methyl-2-thiazolyl)-4-tert-butylbenzamide | [no description available] | low | 0 | 0 | benzamides | |
| N-(5-acetyl-4-methyl-2-thiazolyl)-2-methylbenzamide | [no description available] | low | 0 | 0 | benzamides | |
| 2-ethoxy-N-[5-(methoxymethyl)-1,3,4-thiadiazol-2-yl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| N-(3,4-dimethoxyphenyl)-4-methoxybenzamide | [no description available] | low | 0 | 0 | benzamides | |
| N-[2-[(4-methylanilino)-oxomethyl]phenyl]-3-pyridinecarboxamide | [no description available] | low | 0 | 0 | benzamides | |
| N-[4-(2,5-dimethyl-1-pyrrolyl)phenyl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| N-[4-chloro-3-(trifluoromethyl)phenyl]-3-methoxybenzamide | [no description available] | low | 0 | 0 | benzamides | |
| N-[4-(2-methyl-4-thiazolyl)phenyl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| N-(3-acetamidophenyl)-2-chlorobenzamide | [no description available] | low | 0 | 0 | benzamides | |
| 3-ethoxy-N-(2-thiazolyl)benzamide | [no description available] | low | 0 | 0 | benzamides | |
| 2-bromo-N-(3-methoxyphenyl)benzamide | [no description available] | low | 0 | 0 | benzamides | |
| N-(2,4-difluorophenyl)-3-methoxybenzamide | [no description available] | low | 0 | 0 | benzamides | |
| 4-[[(4-acetyloxy-3-methoxyphenyl)-oxomethyl]amino]benzoic acid | [no description available] | low | 0 | 0 | benzamides | |
| acetic acid [4-[(4-hydroxyanilino)-oxomethyl]-2-methoxyphenyl] ester | [no description available] | low | 0 | 0 | benzamides | |
| N-(4-benzamido-2-chlorophenyl)-2-furancarboxamide | [no description available] | low | 0 | 0 | benzamides | |
| 2-(hydroxymethyl)-N-(phenylmethyl)benzamide | [no description available] | low | 0 | 0 | benzamides | |
| 2-[[(3-methylphenyl)-oxomethyl]amino]-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylic acid | [no description available] | low | 0 | 0 | benzamides | |
| 2-chloro-4-methyl-N-[4-(4-methyl-1-piperazinyl)phenyl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| 2-ethoxy-N-(2-hydroxyphenyl)benzamide | [no description available] | low | 0 | 0 | benzamides | |
| 3-[[(3-chloro-4-ethoxyphenyl)-oxomethyl]amino]benzoic acid | [no description available] | low | 0 | 0 | benzamides | |
| 2-methoxy-N-(4-methylphenyl)-4-(methylthio)benzamide | [no description available] | low | 0 | 0 | benzamides | |
| 3-[[(4-methoxyphenyl)-oxomethyl]amino]-2-thiophenecarboxylic acid methyl ester | [no description available] | low | 0 | 0 | benzamides | |
| 2-methoxy-3-methyl-N-[4-(4-morpholinylmethyl)phenyl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| N-(4-anilinophenyl)-3,4-dimethoxybenzamide | [no description available] | low | 0 | 0 | benzamides | |
| N-[5-(ethylthio)-1,3,4-thiadiazol-2-yl]-4-methylbenzamide | [no description available] | low | 0 | 0 | benzamides | |
| N-[[(6-methyl-4-pyrimidinyl)thio]methyl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| N-(3-acetamidophenyl)-2-methoxybenzamide | [no description available] | low | 0 | 0 | benzamides | |
| 2-bromo-N-[3-(1-oxopropylamino)phenyl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| N-(3-acetylphenyl)-3-ethoxybenzamide | [no description available] | low | 0 | 0 | benzamides | |
| 2-[[(3-bromophenyl)-oxomethyl]amino]-5-hydroxybenzoic acid | [no description available] | low | 0 | 0 | benzamides | |
| 1-azepanyl-[4-[(phenylthio)methyl]phenyl]methanone | [no description available] | low | 0 | 0 | benzamides | |
| 4-chloro-N-[4-(2-imidazo[1,2-a]pyridinyl)phenyl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| 3,4,5-triethoxy-N-(1H-1,2,4-triazol-5-yl)benzamide | [no description available] | low | 0 | 0 | benzamides | |
| 3-[[[3-(4-methoxyphenyl)phenyl]-oxomethyl]amino]benzoic acid | [no description available] | low | 0 | 0 | benzamides | |
| 3-[(4-ethoxyphenoxy)methyl]-N,N-diethylbenzamide | [no description available] | low | 0 | 0 | benzamides | |
| 2-[[anilino(oxo)methyl]amino]-N-(phenylmethyl)benzamide | [no description available] | low | 0 | 0 | benzamides | |
| 4-tert-butyl-N-(4-methyl-3-nitrophenyl)benzamide | [no description available] | low | 0 | 0 | benzamides | |
| N-(3-methoxyphenyl)-4-[(2-methyl-1-oxopropyl)amino]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| N-[(5-ethyl-1,2,4-oxadiazol-3-yl)methyl]-3,4,5-trimethoxybenzamide | [no description available] | low | 0 | 0 | benzamides | |
| 4-chloro-3-[[(2-methyl-3-nitrophenyl)-oxomethyl]amino]benzoic acid methyl ester | [no description available] | low | 0 | 0 | benzamides | |
| N-[3-chloro-4-(1-pyrrolidinyl)phenyl]-2-nitrobenzamide | [no description available] | low | 0 | 0 | benzamides | |
| N-(4-methoxyphenyl)-2-(methylthio)benzamide | [no description available] | low | 0 | 0 | benzamides | |
| N-[3-[[(3,5-dimethoxyphenyl)-oxomethyl]amino]phenyl]carbamic acid ethyl ester | [no description available] | low | 0 | 0 | benzamides | |
| 2,4-dimethyl-N-[4-(1-pyrrolidinyl)phenyl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| N-(7-bromo-3,4-dihydro-2H-1,5-benzodioxepin-8-yl)-3-methoxybenzamide | [no description available] | low | 0 | 0 | benzamides | |
| 5-chloro-N-(2-furanylmethyl)-2-[[(4-methoxyphenyl)-oxomethyl]amino]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| 4-[(2-bromophenoxy)methyl]-N-[4-[(3,5-dimethyl-1-pyrazolyl)methyl]phenyl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| 3-bromo-5-ethoxy-N-(4-fluorophenyl)-4-methoxybenzamide | [no description available] | low | 0 | 0 | benzamides | |
| 2-chloro-N-[3-(5-methyl-1,3-benzoxazol-2-yl)phenyl]-5-(1,2,4-triazol-4-yl)benzamide | [no description available] | low | 0 | 0 | benzamides | |
| 3-[[(3,5-dichloro-4-ethoxyphenyl)-oxomethyl]amino]benzoic acid | [no description available] | low | 0 | 0 | benzamides | |
| 4-[4-[[(3,4-dimethylphenyl)-oxomethyl]amino]phenoxy]phthalic acid | [no description available] | low | 0 | 0 | benzamides | |
| 5-ethyl-2-[[oxo-(3,4,5-trimethoxyphenyl)methyl]amino]-3-thiophenecarboxylic acid ethyl ester | [no description available] | low | 0 | 0 | benzamides | |
| 2-bromo-N-[3-(1-oxobutylamino)phenyl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| 3-chloro-N-[3-nitro-5-(2-pyridinylthio)phenyl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| N-[4-chloro-2-[(2-ethoxyanilino)-oxomethyl]phenyl]-2-furancarboxamide | [no description available] | low | 0 | 0 | benzamides | |
| 4-[[[3-(4-morpholinylsulfonyl)phenyl]-oxomethyl]amino]benzoic acid ethyl ester | [no description available] | low | 0 | 0 | benzamides | |
| 3,4-dimethoxy-N-[4-[oxo(1-piperidinyl)methyl]phenyl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| 2-fluoro-N-[4-[4-[2-furanyl(oxo)methyl]-1-piperazinyl]phenyl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| N-(4-benzamido-3-methylphenyl)-1,3-benzodioxole-5-carboxamide | [no description available] | low | 0 | 0 | benzamides | |
| N-(3-benzamidophenyl)-1,3-benzodioxole-5-carboxamide | [no description available] | low | 0 | 0 | benzamides | |
| N-[2,2-dichloro-1-(4-chlorophenyl)sulfonylethenyl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| 2-[[[3-[2-(4-methylphenyl)sulfonylethylthio]phenyl]-oxomethyl]amino]benzoic acid | [no description available] | low | 0 | 0 | benzamides | |
| 4-chloro-N-[3-chloro-4-(4-morpholinyl)phenyl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| N-(3-methoxyphenyl)-4-(1-oxopropylamino)benzamide | [no description available] | low | 0 | 0 | benzamides | |
| N-[5-(4-tert-butylphenyl)-1,3,4-thiadiazol-2-yl]-4-methylbenzamide | [no description available] | low | 0 | 0 | benzamides | |
| [2-methoxy-4-(methylthio)phenyl]-[4-(phenylmethyl)-1-piperidinyl]methanone | [no description available] | low | 0 | 0 | benzamides; N-acylpiperidine | |
| N-[2,5-diethoxy-4-[[(3-methoxyanilino)-sulfanylidenemethyl]amino]phenyl]-4-methylbenzamide | [no description available] | low | 0 | 0 | benzamides | |
| N-[4-[[anilino(sulfanylidene)methyl]amino]-2,5-diethoxyphenyl]-4-methoxybenzamide | [no description available] | low | 0 | 0 | benzamides | |
| N-[4-[[anilino(sulfanylidene)methyl]amino]-2,5-diethoxyphenyl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| 2-(4-chloro-3-methylphenoxy)acetic acid [4-[(4-methylanilino)-oxomethyl]phenyl] ester | [no description available] | low | 0 | 0 | benzamides | |
| 2-(3-chlorophenoxy)acetic acid [4-[(4-methylanilino)-oxomethyl]phenyl] ester | [no description available] | low | 0 | 0 | benzamides | |
| 2-(4-chloro-2-methylphenoxy)acetic acid [4-[(4-methylanilino)-oxomethyl]phenyl] ester | [no description available] | low | 0 | 0 | benzamides | |
| 3-(1,3-dioxo-2-isoindolyl)propanoic acid [4-[(4-methylanilino)-oxomethyl]phenyl] ester | [no description available] | low | 0 | 0 | benzamides | |
| 5-bromo-2-furancarboxylic acid (3-benzamidophenyl) ester | [no description available] | low | 0 | 0 | benzamides | |
| (4-ethoxyphenyl)-[4-[(4-ethoxyphenyl)-oxomethyl]-1,4-diazepan-1-yl]methanone | [no description available] | low | 0 | 0 | benzamides | |
| [4-[(2-bromophenoxy)methyl]phenyl]-(1-piperidinyl)methanone | [no description available] | low | 0 | 0 | benzamides; N-acylpiperidine | |
| 3-[(4-bromophenoxy)methyl]-N-(5-methyl-3-isoxazolyl)benzamide | [no description available] | low | 0 | 0 | benzamides | |
| 3-methyl-N-[4-[(4-methyl-1-piperazinyl)sulfonyl]phenyl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| N-[4-[methyl(phenyl)sulfamoyl]phenyl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| N-[4-[(N-methylanilino)-oxomethyl]phenyl]-2-furancarboxamide | [no description available] | low | 0 | 0 | benzamides | |
| 3-[[[3-(1-azepanylsulfonyl)-4-chlorophenyl]-oxomethyl]amino]benzoic acid | [no description available] | low | 0 | 0 | benzamides | |
| 2-[2-nitro-4-(trifluoromethyl)phenoxy]-N-phenylbenzamide | [no description available] | low | 0 | 0 | benzamides | |
| 4-chloro-N-[2-(4-methylsulfonyl-1-piperazinyl)phenyl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| 2-[[[(4-methoxyphenyl)-oxomethyl]amino]methyl]-5-phenyl-3-furancarboxylic acid | [no description available] | low | 0 | 0 | benzamides | |
| N-(3,5-dichlorophenyl)-2-(methanesulfonamido)benzamide | [no description available] | low | 0 | 0 | benzamides | |
| N-(5-chloro-2-methylphenyl)-4-[(4-chloro-1-pyrazolyl)methyl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| 2-[[2-[(4-chlorophenyl)thio]-1-oxoethyl]amino]-N-(4-methoxyphenyl)benzamide | [no description available] | low | 0 | 0 | benzamides | |
| 4-methoxy-N-[2-(4-morpholinyl)phenyl]-3-nitrobenzamide | [no description available] | low | 0 | 0 | benzamides | |
| 2-bromo-N-[4-(4-methyl-1-piperazinyl)phenyl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| N-[4-[[[(5-bromo-2-furanyl)-oxomethyl]hydrazo]-oxomethyl]phenyl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| 5-bromo-2-methoxy-3-methyl-N-[4-(4-methylsulfonyl-1-piperazinyl)phenyl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| 4-methoxy-N-[4-[[(1-oxopropylamino)-sulfanylidenemethyl]amino]phenyl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| 2-[[(3,5-dimethoxyphenyl)-oxomethyl]amino]-4,5-dimethoxybenzoic acid methyl ester | [no description available] | low | 0 | 0 | benzamides | |
| 2,4,5-trimethoxy-N-(2-phenylphenyl)benzamide | [no description available] | low | 0 | 0 | benzamides | |
| 3-ethoxy-N-[3-(5-phenyl-1,3,4-oxadiazol-2-yl)phenyl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| 2-[[[3-methyl-4-[[2-(3-nitrophenoxy)-1-oxoethyl]amino]phenyl]-oxomethyl]amino]benzoic acid | [no description available] | low | 0 | 0 | benzamides | |
| 4-methyl-N-[2-methyl-1,3-bis[(4-methyl-1,2,5-oxadiazol-3-yl)oxy]propan-2-yl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| [4-[(2,4-dichlorophenoxy)methyl]phenyl]-(4-methyl-1-piperazinyl)methanone | [no description available] | low | 0 | 0 | benzamides | |
| N-(2-furanylmethyl)-2-[[[2-[(4-methylphenyl)sulfonyl-(phenylmethyl)amino]phenyl]-oxomethyl]amino]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| 2-[(2-cyanophenyl)thio]-N-[4-[dimethylamino(oxo)methyl]phenyl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| N-(2-furanylmethyl)-2-[[oxo-(3,4,5-trimethoxyphenyl)methyl]amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide | [no description available] | low | 0 | 0 | benzamides | |
| N-[3-[[(4-nitrophenyl)-oxomethyl]amino]phenyl]-2-furancarboxamide | [no description available] | low | 0 | 0 | benzamides | |
| N-[(3-benzamidoanilino)-sulfanylidenemethyl]-2-thiophenecarboxamide | [no description available] | low | 0 | 0 | benzamides | |
| 3-chloro-N-[4-[(1-oxo-2-phenylethyl)amino]phenyl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| N-(3,4-dimethoxyphenyl)-4-[(4-phenyl-1-piperazinyl)methyl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| 4-cyano-N-methyl-N-[5-(2-pyridinyl)-1,3,4-thiadiazol-2-yl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| 4-tert-butyl-N-[2,5-dimethoxy-4-[[1-oxo-2-(1-piperidinyl)ethyl]amino]phenyl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| (2,6-difluorophenyl)-[4-(5-fluoro-2-methyl-1-benzimidazolyl)-1-piperidinyl]methanone | [no description available] | low | 0 | 0 | benzamides; N-acylpiperidine | |
| 4-chloro-N-[3-cyano-4-(phenylthio)phenyl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| (4-chlorophenyl)-[4-[[(2,4-dichlorophenyl)thio]methyl]-4-hydroxy-1-piperidinyl]methanone | [no description available] | low | 0 | 0 | benzamides; N-acylpiperidine | |
| N-(4-bromo-2,6-dimethylphenyl)-2-methoxybenzamide | [no description available] | low | 0 | 0 | benzamides | |
| 4-[[(3,6-dichloro-2-methoxyphenyl)-oxomethyl]amino]benzoic acid propyl ester | [no description available] | low | 0 | 0 | benzamides | |
| N-(2,4-dichlorophenyl)-4-phenylbenzamide | [no description available] | low | 0 | 0 | benzamides | |
| 4-butoxy-N-[4-[4-(2-methyl-1-oxopropyl)-1-piperazinyl]phenyl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| fm19g11 | [no description available] | low | 0 | 0 | benzamides | |
| N-[4-[(4,6-dimethyl-2-pyrimidinyl)sulfamoyl]phenyl]-2-nitrobenzamide | [no description available] | low | 0 | 0 | benzamides | |
| 3-[(2,5-dichlorophenoxy)methyl]-N-(2,6-dimethylphenyl)benzamide | [no description available] | low | 0 | 0 | benzamides | |
| 2-[[[(3-methyl-1-oxobutyl)amino]-sulfanylidenemethyl]amino]-N-phenylbenzamide | [no description available] | low | 0 | 0 | benzamides | |
| acetic acid [4-[[3-[5-(2-furanyl)-1,3,4-oxadiazol-2-yl]anilino]-oxomethyl]phenyl] ester | [no description available] | low | 0 | 0 | benzamides | |
| 4-[[(4-tert-butylphenyl)-oxomethyl]amino]-3-methyl-2-sulfanylidene-5-thiazolecarboxylic acid ethyl ester | [no description available] | low | 0 | 0 | benzamides | |
| 3-methoxy-N-(2,3,4-trifluorophenyl)benzamide | [no description available] | low | 0 | 0 | benzamides | |
| 2-phenylacetic acid [2-[4-[(4-ethoxyanilino)-oxomethyl]anilino]-2-oxoethyl] ester | [no description available] | low | 0 | 0 | benzamides | |
| 4-[[(2-nitrophenyl)-oxomethyl]amino]benzoic acid propyl ester | [no description available] | low | 0 | 0 | benzamides | |
| 2-[[oxo-(2,3,4,5,6-pentafluorophenyl)methyl]amino]benzoic acid ethyl ester | [no description available] | low | 0 | 0 | benzamides | |
| 2-bromo-N-[3-(1-oxopentylamino)phenyl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| 4-[(2,4-dichlorophenoxy)methyl]-N-[2-(dimethylamino)ethyl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| 3-methoxy-N-[2-(3-methoxyphenoxy)ethyl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| N-[4-(diethylsulfamoyl)phenyl]-4-(4-morpholinylmethyl)benzamide | [no description available] | low | 0 | 0 | benzamides | |
| 3,5-dimethyl-N-[4-[(1-oxo-2-phenylethyl)amino]phenyl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| 3-[[[3-[(3-nitrophenyl)sulfamoyl]phenyl]-oxomethyl]amino]benzoic acid | [no description available] | low | 0 | 0 | benzamides | |
| 2-[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]-N-(3-methoxyphenyl)benzamide | [no description available] | low | 0 | 0 | benzamides | |
| 4-chloro-3-[(2,5-dimethylphenyl)sulfamoyl]-N-(2-phenylphenyl)benzamide | [no description available] | low | 0 | 0 | benzamides | |
| 4-methyl-N-(2-phenylphenyl)-3-(phenylsulfamoyl)benzamide | [no description available] | low | 0 | 0 | benzamides | |
| 2-[2-[[3-(1,3-benzoxazol-2-yl)anilino]-oxomethyl]phenyl]benzoic acid | [no description available] | low | 0 | 0 | benzamides | |
| 3,4-dimethoxy-N-[4-(2,2,3,3-tetrafluoropropoxy)-3-(trifluoromethyl)phenyl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| 1-azepanyl-[2-[4-(difluoromethylthio)anilino]phenyl]methanone | [no description available] | low | 0 | 0 | benzamides | |
| 3-[[(4-tert-butylphenyl)-oxomethyl]amino]-1H-1,2,4-triazole-5-carboxylic acid methyl ester | [no description available] | low | 0 | 0 | benzamides | |
| 2-bromo-N-(4-ethylphenyl)benzamide | [no description available] | low | 0 | 0 | benzamides | |
| 4-amino-N-(2-methoxyphenyl)benzamide | [no description available] | low | 0 | 0 | benzamides | |
| 4-(difluoromethoxy)-N-[5-[[4-(difluoromethylthio)phenyl]methyl]-2-thiazolyl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| 2-[(4-ethoxyphenyl)sulfonylamino]-N-[2-(4-morpholinyl)phenyl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| 4-(dimethylamino)-N-[2-(1,2,4-triazol-1-yl)-5-(trifluoromethyl)phenyl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| 2-[(2,5-dimethylphenyl)sulfonylamino]-N-[4-(2-pyrimidinylsulfamoyl)phenyl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| 2-[(5-chloro-2-thiophenyl)sulfonylamino]-N-(2-methoxy-5-methylphenyl)benzamide | [no description available] | low | 0 | 0 | benzamides | |
| 4-methoxy-N-[1-methyl-2-oxo-6-(trifluoromethyl)-3-pyridinyl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| N-[4-bromo-3-(trifluoromethyl)phenyl]-2,4,6-trimethylbenzamide | [no description available] | low | 0 | 0 | benzamides | |
| 4-methyl-N-[1-methyl-2-oxo-6-(trifluoromethyl)-3-pyridinyl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| 4-[2-(4-fluoroanilino)-2-oxoethoxy]-3-methoxy-N-[4-(4-methoxyphenyl)-5-methyl-2-thiazolyl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| 3-[3-[2-(2-carbamoylphenoxy)-1-oxoethyl]-2,5-dimethyl-1-pyrrolyl]propanoic acid methyl ester | [no description available] | low | 0 | 0 | benzamides | |
| 4-methyl-N-[4-(2-methyl-4-thiazolyl)phenyl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| 5-(dimethylsulfamoyl)-N-(diphenylmethyl)-2-(1-pyrrolidinyl)benzamide | [no description available] | low | 0 | 0 | benzamides | |
| 2-[(3-fluoro-4-methoxyphenyl)methoxy]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| N-(4-chloro-2-methoxy-5-methylphenyl)-4-[(3,4-difluorophenyl)sulfonylamino]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| 2-[[(3-methylphenyl)-oxomethyl]amino]benzoic acid (3,5-dimethyl-4-isoxazolyl)methyl ester | [no description available] | low | 0 | 0 | benzamides | |
| 4-(dimethylsulfamoyl)-N-(3-methylphenyl)benzamide | [no description available] | low | 0 | 0 | benzamides | |
| N-[5-chloro-2-(4-methyl-1-piperazinyl)phenyl]-3-(dimethylsulfamoyl)benzamide | [no description available] | low | 0 | 0 | benzamides | |
| 3-methoxy-N-(4-methyl-2-thiazolyl)benzamide | [no description available] | low | 0 | 0 | benzamides | |
| 3-(diethylsulfamoyl)-N-(3,5-dimethylphenyl)benzamide | [no description available] | low | 0 | 0 | benzamides | |
| 3,4-dimethyl-N-[4-(4-methylpiperazino)benzyl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| N-[4-(5-oxazolyl)phenyl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| N1-(2,6-dimorpholino-3-pyridyl)-4-methylbenzamide | [no description available] | low | 0 | 0 | benzamides | |
| 2-chloro-N-[3-cyano-4-[(4-methoxyphenyl)thio]phenyl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| N-[4-[(1,1-dioxo-1,4-thiazinan-4-yl)methyl]phenyl]-3,4-dimethylbenzamide | [no description available] | low | 0 | 0 | benzamides | |
| sirtinol | [no description available] | low | 0 | 0 | aldimine; benzamides; naphthols | anti-inflammatory agent; EC 3.5.1.98 (histone deacetylase) inhibitor; Sir2 inhibitor |
| N-[1-(3-methoxyphenyl)-3-(1-naphthalenylamino)-3-oxopropyl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| N-[3-(1-naphthalenylamino)-3-oxo-1-phenylpropyl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| 4-chloro-3-(diethylsulfamoyl)-N-(2-nitrophenyl)benzamide | [no description available] | low | 0 | 0 | benzamides | |
| 3,4,5-trimethoxy-N-[4-[(2-methyl-1-piperidinyl)sulfonyl]phenyl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| N-(4-methoxy-2-nitrophenyl)-3-[(2-methyl-1-oxopropyl)amino]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| 3,4,5-triethoxy-N-[4-(4-methylsulfonyl-1-piperazinyl)phenyl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| 2-[[[4-[[2-(4-chloro-2-methylphenoxy)-1-oxopropyl]amino]phenyl]-oxomethyl]amino]benzoic acid | [no description available] | low | 0 | 0 | benzamides | |
| N-(5-chloro-2-hydroxyphenyl)-2-ethoxybenzamide | [no description available] | low | 0 | 0 | benzamides | |
| N-[2-[(2-furanylmethylamino)-oxomethyl]phenyl]-4-methyl-3-(1-piperidinylsulfonyl)benzamide | [no description available] | low | 0 | 0 | benzamides | |
| 4-methoxy-N-[4-[1-[(4-methoxyanilino)-oxomethyl]cyclopentyl]phenyl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| N-[3-chloro-2-(1-piperidinyl)phenyl]-4-(4-morpholinyl)-3-nitrobenzamide | [no description available] | low | 0 | 0 | benzamides | |
| N-[4-(6-imidazo[2,1-b]thiazolyl)phenyl]-4-methoxy-3-(4-morpholinylsulfonyl)benzamide | [no description available] | low | 0 | 0 | benzamides | |
| norcisapride | [no description available] | low | 0 | 0 | benzamides | |
| prucalopride | [no description available] | low | 0 | 0 | benzamides | |
| Dihydroalatamide | [no description available] | low | 0 | 0 | benzamides | |
| 4-methoxy-N-[2,2,2-trichloro-1-(4-methylanilino)ethyl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| N-(2-hydroxy-5-nitrophenyl)-3-nitrobenzamide | [no description available] | low | 0 | 0 | benzamides | |
| N-[3-(1,3-benzothiazol-2-ylthio)-5-nitrophenyl]-2-fluorobenzamide | [no description available] | low | 0 | 0 | benzamides | |
| N-[2-[5-[(4-tert-butylphenyl)methylthio]-1,3,4-oxadiazol-2-yl]phenyl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| N-butan-2-yl-4-[4-oxo-3-(phenylmethyl)-2-thiazolidinyl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| 4-[3-(2-furanylmethyl)-4-oxo-2-thiazolidinyl]-N-(3-propan-2-yloxypropyl)benzamide | [no description available] | low | 0 | 0 | benzamides | |
| 2-methyl-N-[1-(4-prop-2-enyl-5-sulfanylidene-1H-1,2,4-triazol-3-yl)ethyl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| N-[4-(4-methoxyphenyl)-2-thiazolyl]-N-(2-oxolanylmethyl)benzamide | [no description available] | low | 0 | 0 | benzamides | |
| 3-chloro-4-ethoxy-N-[3-(2-oxazolo[5,4-b]pyridinyl)phenyl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| 4-[[(3-methoxyphenyl)-oxomethyl]amino]benzoic acid | [no description available] | low | 0 | 0 | benzamides | |
| 3-[[oxo-[3-(1-piperidinylsulfonyl)phenyl]methyl]amino]benzoic acid | [no description available] | low | 0 | 0 | benzamides | |
| N-(4-ethoxyphenyl)-2-(hydroxymethyl)benzamide | [no description available] | low | 0 | 0 | benzamides | |
| N-(5-acetyl-2-phenyl-4-sulfanylidene-1H-pyrimidin-6-yl)benzamide | [no description available] | low | 0 | 0 | benzamides | |
| sb-224289 | [no description available] | low | 0 | 0 | 1,2,4-oxadiazole; azaspiro compound; benzamides; organic heterotetracyclic compound | serotonergic antagonist |
| N-[(4-methylphenyl)methyl]-4-(1-pyrrolyl)benzamide | [no description available] | low | 0 | 0 | benzamides | |
| 1-[(4-chlorophenyl)-oxomethyl]-N-[4-(1-piperidinylsulfonyl)phenyl]-3-piperidinecarboxamide | [no description available] | low | 0 | 0 | benzamides; N-acylpiperidine | |
| N-(4-bromophenyl)-2-[(5,6-dimethyl-4-thieno[2,3-d]pyrimidinyl)thio]benzamide | [no description available] | low | 0 | 0 | benzamides; thienopyrimidine | |
| 4-(3,5-dimethyl-1-pyrazolyl)-N-[2-methoxy-5-(4-morpholinylsulfonyl)phenyl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| N-[5-ethyl-3-[(4-fluorophenyl)-(4-morpholinyl)methyl]-2-thiophenyl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| N-cycloheptyl-4-(2-oxolanylmethoxy)benzamide | [no description available] | low | 0 | 0 | benzamides | |
| 2-(4-methoxyphenyl)acetic acid [2-[4-[(4-ethoxyanilino)-oxomethyl]anilino]-2-oxoethyl] ester | [no description available] | low | 0 | 0 | benzamides | |
| 2-methyl-3-nitro-N-[4-[[(1-oxopropylamino)-sulfanylidenemethyl]amino]phenyl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| N-[2-(3-methyl-1-oxobutyl)-3-oxo-1,2,4-thiadiazol-5-yl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| 2-[4-[[(3-chlorophenyl)-oxomethyl]amino]phenyl]propanedioic acid dimethyl ester | [no description available] | low | 0 | 0 | benzamides | |
| N-(3,5-dimethylphenyl)-2-(2-nitroethyl)benzamide | [no description available] | low | 0 | 0 | benzamides | |
| N-[4-[[(4-tert-butylphenyl)-oxomethyl]amino]phenyl]-2-furancarboxamide | [no description available] | low | 0 | 0 | benzamides | |
| N-[3-[(4-ethoxyphenyl)-[4-(2-hydroxyethyl)-1-piperazinyl]methyl]-4,5-dimethyl-2-thiophenyl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| 2-methoxy-N-(5-phenyl-1,2,4-thiadiazol-3-yl)benzamide | [no description available] | low | 0 | 0 | benzamides | |
| N-(3-chlorophenyl)-4-fluoro-3-(thiophen-2-ylmethylsulfamoyl)benzamide | [no description available] | low | 0 | 0 | benzamides | |
| 3-acetamido-N-[(4-ethoxy-3-methoxyphenyl)methyl]-4-[(4-methylphenyl)thio]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| N-[3-(4-morpholinylsulfonyl)phenyl]-4-(2-oxo-1-pyrrolidinyl)benzamide | [no description available] | low | 0 | 0 | benzamides | |
| N,N-dimethylsulfamic acid [3-[(4-methoxyanilino)-oxomethyl]phenyl] ester | [no description available] | low | 0 | 0 | benzamides | |
| N-[1-(benzenesulfonyl)-2,2-dichloroethenyl]-4-methylbenzamide | [no description available] | low | 0 | 0 | benzamides | |
| N-[4-chloro-3-[(4-chlorophenyl)sulfamoyl]phenyl]-4-propan-2-yloxybenzamide | [no description available] | low | 0 | 0 | benzamides | |
| 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1h-imidazol-2-yl)benzamide | [no description available] | low | 0 | 0 | benzamides; benzodioxoles; imidazoles; pyridines | EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor |
| N-[3-[(2-bromo-5-methylphenyl)sulfamoyl]-4-methoxyphenyl]-4-fluorobenzamide | [no description available] | low | 0 | 0 | benzamides | |
| N-[2,5-diethoxy-4-(4-morpholinyl)phenyl]-4-[(3,5-dimethyl-4-isoxazolyl)methoxy]-3-methoxybenzamide | [no description available] | low | 0 | 0 | benzamides | |
| 4-methyl-N-[2-[(5-oxo-2,3-dihydrothiazolo[2,3-b]quinazolin-3-yl)methylthio]phenyl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| 4-cyano-N-[4-thiophen-2-yl-5-(2,2,2-trifluoro-1-oxoethyl)-2-thiazolyl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| 4-(1-azepanylsulfonyl)-N-[5-[(4-chlorophenyl)sulfamoyl]-2-hydroxyphenyl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| N-[4-(4-fluorophenyl)-2-thiazolyl]-3-methoxy-4-[2-(4-morpholinyl)-2-oxoethoxy]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| N-[4-chloro-3-(4-morpholinylsulfonyl)phenyl]-4-(2-oxolanylmethoxy)benzamide | [no description available] | low | 0 | 0 | benzamides | |
| N-[3-[(4-chlorophenyl)methylthio]-1H-1,2,4-triazol-5-yl]-4-cyanobenzamide | [no description available] | low | 0 | 0 | benzamides | |
| 2-(4-methylphenoxy)-N-[2-[oxo(1-piperidinyl)methyl]phenyl]acetamide | [no description available] | low | 0 | 0 | benzamides; N-acylpiperidine | |
| imd 0354 | [no description available] | low | 0 | 0 | benzamides | |
| N-(3-chlorophenyl)-3-[ethyl(phenyl)sulfamoyl]-4-fluorobenzamide | [no description available] | low | 0 | 0 | benzamides | |
| 4-tert-butyl-N-[3-[4-[3-[[(4-tert-butylphenyl)-oxomethyl]amino]propyl]-1-piperazinyl]propyl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| 2-nitro-4-[(6-nitro-4-quinolinyl)amino]-N-[4-(pyridin-4-ylamino)phenyl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| 4-amino-5-chloro-N-[(3R,4S)-1-[3-(4-fluorophenoxy)propyl]-3-methoxy-4-piperidinyl]-2-methoxybenzamide | [no description available] | low | 0 | 0 | benzamides | |
| tiapridex | [no description available] | low | 0 | 0 | benzamides | |
| [2-methoxy-5-[[4-(4-methylphenyl)-1-phthalazinyl]amino]phenyl]-(1-piperidinyl)methanone | [no description available] | low | 0 | 0 | benzamides; N-acylpiperidine | |
| axitinib | [no description available] | low | 0 | 0 | aryl sulfide; benzamides; indazoles; pyridines | antineoplastic agent; tyrosine kinase inhibitor; vascular endothelial growth factor receptor antagonist |
| 4-[(2,4-dioxo-1H-thieno[3,2-d]pyrimidin-3-yl)methyl]-N-(3-ethylphenyl)benzamide | [no description available] | low | 0 | 0 | benzamides | |
| LSM-32377 | [no description available] | low | 0 | 0 | benzamides | |
| ispinesib | [no description available] | low | 0 | 0 | benzamides | |
| fk 866 | [no description available] | low | 0 | 0 | benzamides; N-acylpiperidine | |
| 4-acetamido-N-(2-amino-5-thiophen-2-ylphenyl)benzamide | [no description available] | low | 0 | 0 | benzamides | |
| [4-[[4-(1-benzothiophen-2-yl)-2-pyrimidinyl]amino]phenyl]-[4-(1-pyrrolidinyl)-1-piperidinyl]methanone | [no description available] | low | 0 | 0 | benzamides; N-acylpiperidine | |
| midostaurin | [no description available] | low | 0 | 0 | benzamides; gamma-lactam; indolocarbazole; organic heterooctacyclic compound | antineoplastic agent; EC 2.7.11.13 (protein kinase C) inhibitor |
| bms201038 | [no description available] | low | 0 | 0 | (trifluoromethyl)benzenes; benzamides; fluorenes; piperidines | anticholesteremic drug; MTP inhibitor |
| mocetinostat | [no description available] | low | 0 | 0 | aminopyrimidine; benzamides; pyridines; secondary amino compound; secondary carboxamide; substituted aniline | antineoplastic agent; apoptosis inducer; autophagy inducer; cardioprotective agent; EC 3.5.1.98 (histone deacetylase) inhibitor; hepatotoxic agent |
| cgp 74588 | [no description available] | low | 0 | 0 | benzamides | |
| zm 447439 | [no description available] | low | 0 | 0 | aromatic ether; benzamides; morpholines; polyether; quinazolines; secondary amino compound; tertiary amino compound | antineoplastic agent; apoptosis inducer; Aurora kinase inhibitor |
| tak-715 | [no description available] | low | 0 | 0 | benzamides | |
| masitinib | [no description available] | low | 0 | 0 | 1,3-thiazoles; benzamides; N-alkylpiperazine; pyridines | antineoplastic agent; antirheumatic drug; tyrosine kinase inhibitor |
| N-(3-cyanophenyl)-2'-methyl-5'-(5-methyl-1,3,4-oxadiazol-2-yl)biphenyl-4-carboxamide | [no description available] | low | 0 | 0 | 1,3,4-oxadiazoles; benzamides; biphenyls; nitrile | EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor |
| betrixaban | [no description available] | low | 0 | 0 | benzamides; guanidines; monochloropyridine; monomethoxybenzene; secondary carboxamide | anticoagulant; EC 3.4.21.6 (coagulation factor Xa) inhibitor |
| nigerloxin | [no description available] | low | 0 | 0 | aromatic ether; benzamides; benzoic acids; phenols; styrenes | antioxidant; Aspergillus metabolite; EC 1.1.1.21 (aldehyde reductase) inhibitor; lipoxygenase inhibitor; radical scavenger |
| myxochelin b | [no description available] | low | 0 | 0 | benzamides; catechols | bacterial metabolite; siderophore |
| eluxadoline | [no description available] | low | 0 | 0 | amino acid amide; benzamides; imidazoles; L-phenylalanine derivative; methoxybenzoic acid | delta-opioid receptor antagonist; gastrointestinal drug; kappa-opioid receptor agonist; mu-opioid receptor agonist |
| N-[4-(2-tert-butylphenyl)sulfonylphenyl]-2,3,4-trihydroxy-5-[(2-propan-2-ylphenyl)methyl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| N-[5-[[5-[(4-acetyl-1-piperazinyl)-oxomethyl]-4-methoxy-2-methylphenyl]thio]-2-thiazolyl]-4-[(3,3-dimethylbutan-2-ylamino)methyl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| chir 090 | [no description available] | low | 0 | 0 | acetylenic compound; benzamides; hydroxamic acid; L-threonine derivative; morpholines | antimicrobial agent; EC 3.5.1.108 (UDP-3-O-acyl-N-acetylglucosamine deacetylase) inhibitor; lipopolysaccharide biosynthesis inhibitor |
| ki11502 | [no description available] | low | 0 | 0 | aromatic ether; benzamides; quinolines; thioureas | antineoplastic agent; apoptosis inducer; EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor |
| az-628 | [no description available] | low | 0 | 0 | benzamides | |
| at 13387 | [no description available] | low | 0 | 0 | benzamides; isoindoles; N-alkylpiperazine; resorcinols; tertiary carboxamide | antineoplastic agent; Hsp90 inhibitor |
| 4-[[[2-(cyclohexylamino)-3,4-dioxo-1-cyclobutenyl]amino]methyl]-N-(4-ethoxyphenyl)benzamide | [no description available] | low | 0 | 0 | benzamides | |
| chidamide | [no description available] | low | 0 | 0 | benzamides | |
| N-(3,5-dichlorophenyl)-4-[(2,4-dioxo-1H-thieno[3,2-d]pyrimidin-3-yl)methyl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| mdv 3100 | [no description available] | low | 0 | 0 | (trifluoromethyl)benzenes; benzamides; imidazolidinone; monofluorobenzenes; nitrile; thiocarbonyl compound | androgen antagonist; antineoplastic agent |
| 3-nitro-4-(2-oxolanylmethylamino)-N-(2-phenylethyl)benzamide | [no description available] | low | 0 | 0 | benzamides | |
| 2-({2-[(3-hydroxyphenyl)amino]pyrimidin-4-yl}amino)benzamide | [no description available] | low | 0 | 0 | aminopyrimidine; benzamides | protein kinase inhibitor |
| N-[3-[2-(4-chloroanilino)-4-thiazolyl]phenyl]-3-(trifluoromethyl)benzamide | [no description available] | low | 0 | 0 | benzamides | |
| 3-(trifluoromethyl)-N-[4-[2-[3-(trifluoromethyl)anilino]-4-thiazolyl]phenyl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| 2-amino-N-[3-methoxy-5-[oxo-[3-(trifluoromethyl)anilino]methyl]phenyl]-5-oxazolecarboxamide | [no description available] | low | 0 | 0 | benzamides | |
| 2-amino-N-[3-methoxy-5-[oxo-[3-(trifluoromethyl)anilino]methyl]phenyl]-4-thiazolecarboxamide | [no description available] | low | 0 | 0 | benzamides | |
| 2-amino-N-[3-methoxy-5-[oxo-[3-(trifluoromethyl)anilino]methyl]phenyl]-4-pyridinecarboxamide | [no description available] | low | 0 | 0 | benzamides | |
| 3-(4-bromophenyl)-N-[5-[[4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)anilino]-oxomethyl]-2-methylphenyl]-1H-pyrazole-5-carboxamide | [no description available] | low | 0 | 0 | benzamides | |
| N-[3-amino-1-[4-[2-(4-methoxyphenyl)ethylamino]-3-nitrophenyl]-3-oxopropyl]-4-bromobenzamide | [no description available] | low | 0 | 0 | benzamides | |
| nvp-bhg712 | [no description available] | low | 0 | 0 | benzamides | |
| respirantin | [no description available] | low | 0 | 0 | benzamides; cyclodepsipeptide; formamides; phenols | antimicrobial agent; antineoplastic agent; metabolite |
| N-[5-[[5-[(4-acetyl-1-piperazinyl)-oxomethyl]-4-methoxy-2-methylphenyl]thio]-2-thiazolyl]-4-[(3-methylbutan-2-ylamino)methyl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| 2-[(6-chloro-3-pyridinyl)sulfonylamino]-N-[(4-methylphenyl)methyl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| 2-[[4-(2-hydroxyethylamino)-6-(1-pyrrolidinyl)-1,3,5-triazin-2-yl]amino]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| gdc 0449 | [no description available] | low | 0 | 0 | benzamides; monochlorobenzenes; pyridines; sulfone | antineoplastic agent; Hedgehog signaling pathway inhibitor; SMO receptor antagonist; teratogenic agent |
| 3-[[1-[1-(methylthio)propan-2-yl]-4-piperidinyl]oxy]-N-(2-pyridinylmethyl)benzamide | [no description available] | low | 0 | 0 | benzamides | |
| 3-[[1-(dimethylsulfamoyl)-4-piperidinyl]oxy]-N-[(3-methyl-5-isoxazolyl)methyl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| ponatinib | [no description available] | low | 0 | 0 | (trifluoromethyl)benzenes; acetylenic compound; benzamides; imidazopyridazine; N-methylpiperazine | antineoplastic agent; tyrosine kinase inhibitor |
| N-cyclopropyl-3-{4-[(cyclopropylmethyl)carbamoyl]phenyl}-4-methylbenzamide | [no description available] | low | 0 | 0 | benzamides; biphenyls; cyclopropanes; dicarboxylic acid diamide | EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor |
| 4-tert-butyl-N-[5-[[2-oxo-2-(2-oxolanylmethylamino)ethyl]thio]-1,3,4-thiadiazol-2-yl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| 4-ethoxy-N-[5-[[2-oxo-2-(2-oxolanylmethylamino)ethyl]thio]-1,3,4-thiadiazol-2-yl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| GRL-0617 | [no description available] | low | 0 | 0 | benzamides; naphthalenes; secondary carboxamide; substituted aniline | anticoronaviral agent; protease inhibitor |
| n-(cyanomethyl)-4-(2-((4-(4-morpholinyl)phenyl)amino)-4-pyrimidinyl)benzamide | [no description available] | low | 0 | 0 | aminopyrimidine; benzamides; morpholines; nitrile; secondary amino compound; tertiary amino compound | anti-anaemic agent; antineoplastic agent; apoptosis inducer; EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor |
| N-(2,6-difluorophenyl)-5-[3-[2-[5-ethyl-2-methoxy-4-[4-(4-methylsulfonyl-1-piperazinyl)-1-piperidinyl]anilino]-4-pyrimidinyl]-2-imidazo[1,2-a]pyridinyl]-2-methoxybenzamide | [no description available] | low | 0 | 0 | benzamides | |
| entrectinib | [no description available] | low | 0 | 0 | benzamides; difluorobenzene; indazoles; N-methylpiperazine; oxanes; secondary amino compound; secondary carboxamide | antibacterial agent; antineoplastic agent; apoptosis inducer; EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor |
| ixazomib | [no description available] | low | 0 | 0 | benzamides; boronic acids; dichlorobenzene; glycine derivative | antineoplastic agent; apoptosis inducer; drug metabolite; orphan drug; proteasome inhibitor |
| N-(2-chlorophenyl)-4-[[2-[4-[2-(4-ethyl-1-piperazinyl)-2-oxoethyl]anilino]-5-fluoro-4-pyrimidinyl]amino]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| N-[(2S,3S)-5-[(2S)-1-hydroxypropan-2-yl]-3-methyl-2-(methylaminomethyl)-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-10-yl]-4-(2-thiazolyl)benzamide | [no description available] | low | 0 | 0 | benzamides | |
| N-(2-aminophenyl)-4-[[[(2S,3S)-10-[[cyclohexyl(oxo)methyl]amino]-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-2-yl]methyl-methylamino]methyl]benzamide | [no description available] | low | 0 | 0 | benzamides | |
| KOM70144 | [no description available] | low | 0 | 0 | acetamides; benzamides; naphthalenes; secondary carboxamide | anticoronaviral agent; protease inhibitor |
| iwr-1 endo | [no description available] | low | 0 | 0 | benzamides; bridged compound; dicarboximide; quinolines | axin stabilizer; Wnt signalling inhibitor |
| ulixacaltamide | [no description available] | low | 0 | 0 | benzamides; monochlorobenzenes; monofluorobenzenes; piperidines; secondary carboxamide | non-narcotic analgesic; T-type calcium channel blocker |
| xl765 | [no description available] | low | 0 | 0 | aromatic amine; aromatic ether; benzamides; quinoxaline derivative; sulfonamide | antineoplastic agent; EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor; mTOR inhibitor |
| azd4547 | [no description available] | low | 0 | 0 | benzamides; N-arylpiperazine; pyrazoles | fibroblast growth factor receptor antagonist |
| N-[4-(1-benzoyl-4-piperidinyl)butyl]-3-(3-pyridinyl)-2-propenamide | [no description available] | low | 0 | 0 | benzamides; N-acylpiperidine | |
| entecavir | [no description available] | low | 0 | 0 | benzamides; N-acylpiperidine | |
| acp-196 | [no description available] | low | 0 | 0 | aromatic amine; benzamides; imidazopyrazine; pyridines; pyrrolidinecarboxamide; secondary carboxamide; tertiary carboxamide; ynone | antineoplastic agent; apoptosis inducer; EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor |
| pf-06463922 | [no description available] | low | 0 | 0 | aminopyridine; aromatic ether; azamacrocycle; benzamides; cyclic ether; monofluorobenzenes; nitrile; organic heterotetracyclic compound; pyrazoles | antineoplastic agent; EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor |
| DDR1-IN-1 | [no description available] | low | 0 | 0 | (trifluoromethyl)benzenes; aromatic ether; benzamides; N-alkylpiperazine; oxindoles; secondary carboxamide | EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor |
| N-[2-methyl-5-[oxo-[3-(1-oxoprop-2-enylamino)-5-(trifluoromethyl)anilino]methyl]phenyl]-5-isoxazolecarboxamide | [no description available] | low | 0 | 0 | benzamides | |
| PF-06446846 | [no description available] | low | 0 | 0 | benzamides; monochloropyridine; piperidines; tertiary carboxamide; triazolopyridine | antilipemic drug; EC 3.4.21.61 (kexin) inhibitor |
| 5,10-methylenetetrahydrofolic acid | [no description available] | low | 0 | 0 | benzamides; methylenetetrahydrofolic acid | |
| N-cyclohexyl-3-methyl-N-[(4-oxo-1H-quinazolin-2-yl)methyl]benzamide | [no description available] | low | 0 | 0 | benzamides |
| Condition | Indicated | Relationship Strength | Studies | Trials |
|---|---|---|---|---|
| Congenital Zika Syndrome | 0 | low | 1 | 0 |
| Congenital Zika Virus Infection | 0 | low | 1 | 0 |
| Disease Models, Animal | 0 | low | 1 | 0 |
| Fever, Zika | 0 | low | 1 | 0 |
| Invasiveness, Neoplasm | 0 | low | 1 | 0 |
| Malignant Melanoma | 0 | low | 1 | 0 |
| Melanoma | 0 | low | 1 | 0 |
| Metastase | 0 | low | 1 | 0 |
| Metastases, Neoplasm | 0 | low | 1 | 0 |
| Metastasis | 0 | low | 1 | 0 |
| Metastasis, Neoplasm | 0 | low | 1 | 0 |
| Neoplasm Invasion | 0 | low | 1 | 0 |
| Neoplasm Invasiveness | 0 | low | 1 | 0 |
| Neoplasm Metastases | 0 | low | 1 | 0 |
| Neoplasm Metastasis | 0 | low | 1 | 0 |
| Zika Fever | 0 | low | 1 | 0 |
| Zika Virus Disease | 0 | low | 1 | 0 |
| Zika Virus Infection | 0 | low | 1 | 0 |
| ZikV Infection | 0 | low | 1 | 0 |
| Article | Year |
|---|---|
| A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Molecular pharmacology, Volume: 96, Issue: 5 | 2019 |
| [information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | |