| Assay ID | Title | Year | Journal | Article |
|---|
| AID730542 | Antimalarial activity against schizont stage of chloroquine-sensitive Plasmodium falciparum 3D7 after more than 40 hrs by Giemsa staining-based light microscopic analysis | 2013 | Journal of medicinal chemistry, Jan-10, Volume: 56, Issue:1
| Synthesis and insight into the structure-activity relationships of chalcones as antimalarial agents. |
| AID1697935 | Antiproliferative activity against human K562 cells assessed as reduction in cell viability at 25 uM after 72 hrs by MTS assay relative to control | 2020 | Journal of natural products, 10-23, Volume: 83, Issue:10
| Natural and Semisynthetic Chalcones as Dual FLT3 and Microtubule Polymerization Inhibitors. |
| AID666600 | Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO production incubated for 2 hrs prior to LPS-challenge measured after 22 hrs by Griess method relative to untreated control | 2012 | European journal of medicinal chemistry, Aug, Volume: 54 | Rational design, synthesis, and pharmacological properties of pyranochalcone derivatives as potent anti-inflammatory agents. |
| AID252018 | In-vitro antileishmanial activity was tested against extracellular promastigotes of Leishmania donovani at dose of 50 ug/mL | 2004 | Bioorganic & medicinal chemistry letters, Aug-02, Volume: 14, Issue:15
| A convenient and biogenetic type synthesis of few naturally occurring chromeno dihydrochalcones and their in vitro antileishmanial activity. |
| AID1524945 | Inhibition of AChE (unknown origin) using acetylthiocholine iodide as substrate by spectrophotometry based Ellman's method | 2019 | Bioorganic & medicinal chemistry letters, 05-15, Volume: 29, Issue:10
| Bioactivity-guided identification of flavonoids with cholinesterase and β-amyloid peptide aggregation inhibitory effects from the seeds of Millettia pachycarpa. |
| AID1697933 | Antiproliferative activity against human MV4-11 cells assessed as reduction in cell viability at 25 uM after 72 hrs by MTS assay relative to control | 2020 | Journal of natural products, 10-23, Volume: 83, Issue:10
| Natural and Semisynthetic Chalcones as Dual FLT3 and Microtubule Polymerization Inhibitors. |
| AID1697934 | Antiproliferative activity against human MV4-11 cells assessed as reduction in cell viability at 50 uM after 72 hrs by MTS assay relative to control | 2020 | Journal of natural products, 10-23, Volume: 83, Issue:10
| Natural and Semisynthetic Chalcones as Dual FLT3 and Microtubule Polymerization Inhibitors. |
| AID1524946 | Inhibition of BChE (unknown origin) using butyrylthiocholine iodide as substrate by spectrophotometry based Ellman's method | 2019 | Bioorganic & medicinal chemistry letters, 05-15, Volume: 29, Issue:10
| Bioactivity-guided identification of flavonoids with cholinesterase and β-amyloid peptide aggregation inhibitory effects from the seeds of Millettia pachycarpa. |
| AID1524944 | Inhibition of BChE (unknown origin) at 20 ug/mL using butyrylthiocholine iodide as substrate by spectrophotometry based Ellman's method | 2019 | Bioorganic & medicinal chemistry letters, 05-15, Volume: 29, Issue:10
| Bioactivity-guided identification of flavonoids with cholinesterase and β-amyloid peptide aggregation inhibitory effects from the seeds of Millettia pachycarpa. |
| AID1697936 | Antiproliferative activity against human K562 cells assessed as reduction in cell viability at 50 uM after 72 hrs by MTS assay relative to control | 2020 | Journal of natural products, 10-23, Volume: 83, Issue:10
| Natural and Semisynthetic Chalcones as Dual FLT3 and Microtubule Polymerization Inhibitors. |
| AID1524947 | Selectivity index, ratio of IC50 for inhibition of AChE (unknown origin) to IC50 for inhibition of BChE (unknown origin) | 2019 | Bioorganic & medicinal chemistry letters, 05-15, Volume: 29, Issue:10
| Bioactivity-guided identification of flavonoids with cholinesterase and β-amyloid peptide aggregation inhibitory effects from the seeds of Millettia pachycarpa. |
| AID251991 | In-vitro antileishmanial activity was tested against intracellular amastigotes of Leishmania donovani at dose 50 ug/mL | 2004 | Bioorganic & medicinal chemistry letters, Aug-02, Volume: 14, Issue:15
| A convenient and biogenetic type synthesis of few naturally occurring chromeno dihydrochalcones and their in vitro antileishmanial activity. |
| AID1524943 | Inhibition of AChE (unknown origin) at 20 ug/mL using acetylthiocholine iodide as substrate by spectrophotometry based Ellman's method | 2019 | Bioorganic & medicinal chemistry letters, 05-15, Volume: 29, Issue:10
| Bioactivity-guided identification of flavonoids with cholinesterase and β-amyloid peptide aggregation inhibitory effects from the seeds of Millettia pachycarpa. |
| AID730539 | Antimalarial activity against schizont stage of chloroquine-sensitive Plasmodium falciparum 3D7 assessed as reduction in parasitemia at 50 ug/ml after more than 40 hrs by Giemsa staining-based light microscopy | 2013 | Journal of medicinal chemistry, Jan-10, Volume: 56, Issue:1
| Synthesis and insight into the structure-activity relationships of chalcones as antimalarial agents. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |