| Assay ID | Title | Year | Journal | Article |
|---|
| AID1347153 | Confirmatory screen GU AMC qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1347149 | Furin counterscreen qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1347161 | Confirmatory screen NINDS Rhodamine qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1347169 | Tertiary RLuc qRT-PCR qHTS assay for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1347163 | 384 well plate NINDS AMC confirmatory qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1347168 | HepG2 cells viability qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1347164 | 384 well plate NINDS Rhodamine confirmatory qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1347167 | Vero cells viability qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1347152 | Confirmatory screen NINDS AMC qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1508630 | Primary qHTS for small molecule stabilizers of the endoplasmic reticulum resident proteome: Secreted ER Calcium Modulated Protein (SERCaMP) assay | 2021 | Cell reports, 04-27, Volume: 35, Issue:4
| A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. |
| AID1347158 | ZIKV-mCherry secondary qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1347154 | Primary screen GU AMC qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1347156 | DAPI mCherry counterscreen qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1385140 | Aqueous solubility of the compound in DMSO/H2O2 solution at 2.5 mM | 2018 | ACS medicinal chemistry letters, Jul-12, Volume: 9, Issue:7
| Design, Synthesis, and Biological Evaluation of Allosteric Effectors That Enhance CO Release from Carboxyhemoglobin. |
| AID231998 | Ratio of endothelin A binding affinity to endothelin B binding affinity | 1998 | Bioorganic & medicinal chemistry letters, Aug-18, Volume: 8, Issue:16
| Discovery of IRL 3461: a novel and potent endothelin antagonist with balanced ETA/ETB affinity. |
| AID1669222 | Inhibition of human recombinant-Sialin expressed in HEK293 cells assessed as reduction in [3H]Neu5Ac uptake at 30 to 300 uM incubated for 15 mins by liquid scintillation counting method | 2020 | Journal of medicinal chemistry, 08-13, Volume: 63, Issue:15
| Amino Acids Bearing Aromatic or Heteroaromatic Substituents as a New Class of Ligands for the Lysosomal Sialic Acid Transporter Sialin. |
| AID1631617 | Displacement of [125I]ET-1 from human ET-A receptor expressed in CHO cell membrane incubated for 2 hrs | 2016 | Journal of medicinal chemistry, 09-22, Volume: 59, Issue:18
| Endothelin-Receptor Antagonists beyond Pulmonary Arterial Hypertension: Cancer and Fibrosis. |
| AID1631618 | Displacement of [125I]ET-1 from human ET-B receptor expressed in CHO cell membrane incubated for 2 hrs | 2016 | Journal of medicinal chemistry, 09-22, Volume: 59, Issue:18
| Endothelin-Receptor Antagonists beyond Pulmonary Arterial Hypertension: Cancer and Fibrosis. |
| AID66852 | Binding affinity to Endothelin B receptor | 1998 | Bioorganic & medicinal chemistry letters, Aug-18, Volume: 8, Issue:16
| Discovery of IRL 3461: a novel and potent endothelin antagonist with balanced ETA/ETB affinity. |
| AID1385136 | Binding affinity to hemoglobin (unknown origin) assessed as increase in release of carbon monooxide from carboxyhemoglobin by measuring half life of carboxyhemoglobin at 20:1 compound/Hb tetramer ratio incubated for 1 hr measured every 15 mins for 90 mins | 2018 | ACS medicinal chemistry letters, Jul-12, Volume: 9, Issue:7
| Design, Synthesis, and Biological Evaluation of Allosteric Effectors That Enhance CO Release from Carboxyhemoglobin. |
| AID1385141 | Binding affinity to hemoglobin (unknown origin) assessed as partial oxygen pressure at which 50% of Hb is oxygenated (Rvb = 17 +/- 0.3 mmHg) | 2018 | ACS medicinal chemistry letters, Jul-12, Volume: 9, Issue:7
| Design, Synthesis, and Biological Evaluation of Allosteric Effectors That Enhance CO Release from Carboxyhemoglobin. |
| AID68655 | Binding affinity to Endothelin A receptor | 1998 | Bioorganic & medicinal chemistry letters, Aug-18, Volume: 8, Issue:16
| Discovery of IRL 3461: a novel and potent endothelin antagonist with balanced ETA/ETB affinity. |
| AID1385139 | Hemolytic activity against human RBC assessed as increase in fraction of extracellular Hb level at 1 mM after 1 hr | 2018 | ACS medicinal chemistry letters, Jul-12, Volume: 9, Issue:7
| Design, Synthesis, and Biological Evaluation of Allosteric Effectors That Enhance CO Release from Carboxyhemoglobin. |
| AID1385137 | Binding affinity to hemoglobin (unknown origin) assessed as increase in release of carbon monooxide from carboxyhemoglobin by measuring half life of carboxyhemoglobin at 5:1 compound/Hb tetramer ratio incubated for 1 hr measured every 15 mins for 90 mins | 2018 | ACS medicinal chemistry letters, Jul-12, Volume: 9, Issue:7
| Design, Synthesis, and Biological Evaluation of Allosteric Effectors That Enhance CO Release from Carboxyhemoglobin. |
| AID1345807 | Human ETB receptor (Endothelin receptors) | 1996 | British journal of pharmacology, Oct, Volume: 119, Issue:4
| Characterization of the binding of endothelin ETB selective ligands in human and rat heart. |
| AID1347172 | Secondary qRT-PCR qHTS assay for selected Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1347170 | Vero cells viability counterscreen for qRT-PCR qHTS assay of selected Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |