| Assay ID | Title | Year | Journal | Article |
|---|
| AID504812 | Inverse Agonists of the Thyroid Stimulating Hormone Receptor: HTS campaign | 2010 | Endocrinology, Jul, Volume: 151, Issue:7
| A small molecule inverse agonist for the human thyroid-stimulating hormone receptor. |
| AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1
| High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID1745845 | Primary qHTS for Inhibitors of ATXN expression | | | |
| AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1
| High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1
| High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID504810 | Antagonists of the Thyroid Stimulating Hormone Receptor: HTS campaign | 2010 | Endocrinology, Jul, Volume: 151, Issue:7
| A small molecule inverse agonist for the human thyroid-stimulating hormone receptor. |
| AID651635 | Viability Counterscreen for Primary qHTS for Inhibitors of ATXN expression | | | |
| AID588519 | A screen for compounds that inhibit viral RNA polymerase binding and polymerization activities | 2011 | Antiviral research, Sep, Volume: 91, Issue:3
| High-throughput screening identification of poliovirus RNA-dependent RNA polymerase inhibitors. |
| AID540299 | A screen for compounds that inhibit the MenB enzyme of Mycobacterium tuberculosis | 2010 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 20, Issue:21
| Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. |
| AID322158 | Antifungal activity against Candida albicans C 130-2000 after 48 hrs by CLSI M27-A2 method | 2008 | Bioorganic & medicinal chemistry, Jan-01, Volume: 16, Issue:1
| N-Phenyl and N-phenylalkyl-maleimides acting against Candida spp.: time-to-kill, stability, interaction with maleamic acids. |
| AID1687064 | Inhibition of Staphylococcus aureus MurA expressed in Escherichia coli assessed as residual activity at 100 uM using UNAG and PEP as substrate preincubated for 30 mins in presence of UNAG followed by PEP addition and measured after 15 mins by malachite gr | 2018 | European journal of medicinal chemistry, Dec-05, Volume: 160 | A road map for prioritizing warheads for cysteine targeting covalent inhibitors. |
| AID322156 | Antifungal activity against Candida albicans C 128-2000 after 48 hrs by CLSI M27-A2 method | 2008 | Bioorganic & medicinal chemistry, Jan-01, Volume: 16, Issue:1
| N-Phenyl and N-phenylalkyl-maleimides acting against Candida spp.: time-to-kill, stability, interaction with maleamic acids. |
| AID322168 | Antifungal activity against Candida albicans ATCC 10231 pre-incubated for 1 day analysed after 24 hrs by CLSI M27-A2 method | 2008 | Bioorganic & medicinal chemistry, Jan-01, Volume: 16, Issue:1
| N-Phenyl and N-phenylalkyl-maleimides acting against Candida spp.: time-to-kill, stability, interaction with maleamic acids. |
| AID596529 | Antifungal activity against Trichophyton mentagrophytes ATCC 9972 | 2011 | Bioorganic & medicinal chemistry, May-01, Volume: 19, Issue:9
| Antifungal, cytotoxic and SAR studies of a series of N-alkyl, N-aryl and N-alkylphenyl-1,4-pyrrolediones and related compounds. |
| AID1640018 | Luciferase/luciferin-expressing antifolate-resistant parasites were used to infect a culture of HepG2 cells that were pre-incubated with compounds. Infected hepatocytes emit light due to the luciferase reaction. Assay results are presented as the percent | 2018 | Science (New York, N.Y.), 12-07, Volume: 362, Issue:6419
| Open-source discovery of chemical leads for next-generation chemoprotective antimalarials. |
| AID322160 | Antifungal activity against Candida parapsilosis C 124-2000 after 48 hrs by CLSI M27-A2 method | 2008 | Bioorganic & medicinal chemistry, Jan-01, Volume: 16, Issue:1
| N-Phenyl and N-phenylalkyl-maleimides acting against Candida spp.: time-to-kill, stability, interaction with maleamic acids. |
| AID596447 | Antifungal activity against Aspergillus fumigatus ATCC 26934 | 2011 | Bioorganic & medicinal chemistry, May-01, Volume: 19, Issue:9
| Antifungal, cytotoxic and SAR studies of a series of N-alkyl, N-aryl and N-alkylphenyl-1,4-pyrrolediones and related compounds. |
| AID322152 | Antifungal activity against Candida albicans ATCC 10231 after 48 hrs by CLSI M27-A2 method | 2008 | Bioorganic & medicinal chemistry, Jan-01, Volume: 16, Issue:1
| N-Phenyl and N-phenylalkyl-maleimides acting against Candida spp.: time-to-kill, stability, interaction with maleamic acids. |
| AID322161 | Antifungal activity against Candida lusitaniae C 131-2000 after 48 hrs by CLSI M27-A2 method | 2008 | Bioorganic & medicinal chemistry, Jan-01, Volume: 16, Issue:1
| N-Phenyl and N-phenylalkyl-maleimides acting against Candida spp.: time-to-kill, stability, interaction with maleamic acids. |
| AID1687065 | Inhibition of Escherichia coli MurA assessed as residual activity at 100 uM using UNAG and PEP as substrate preincubated for 30 mins in presence of UNAG followed by PEP addition and measured after 15 mins by malachite green colorimetric assay relative to | 2018 | European journal of medicinal chemistry, Dec-05, Volume: 160 | A road map for prioritizing warheads for cysteine targeting covalent inhibitors. |
| AID1687066 | Inhibition of Escherichia coli MurA assessed as residual activity at 100 uM using UNAG and PEP as substrate preincubated for 30 mins in presence of UNAG followed by PEP addition and measured after 15 mins in presence of 5 mM cysteine by malachite green co | 2018 | European journal of medicinal chemistry, Dec-05, Volume: 160 | A road map for prioritizing warheads for cysteine targeting covalent inhibitors. |
| AID322170 | Antifungal activity against Candida albicans ATCC 10231 pre-incubated for 3 days analysed after 24 hrs by CLSI M27-A2 method | 2008 | Bioorganic & medicinal chemistry, Jan-01, Volume: 16, Issue:1
| N-Phenyl and N-phenylalkyl-maleimides acting against Candida spp.: time-to-kill, stability, interaction with maleamic acids. |
| AID596528 | Antifungal activity against Trichophyton rubrum C 113 2000 | 2011 | Bioorganic & medicinal chemistry, May-01, Volume: 19, Issue:9
| Antifungal, cytotoxic and SAR studies of a series of N-alkyl, N-aryl and N-alkylphenyl-1,4-pyrrolediones and related compounds. |
| AID596443 | Antifungal activity against Candida albicans ATCC 10213 | 2011 | Bioorganic & medicinal chemistry, May-01, Volume: 19, Issue:9
| Antifungal, cytotoxic and SAR studies of a series of N-alkyl, N-aryl and N-alkylphenyl-1,4-pyrrolediones and related compounds. |
| AID596526 | Antifungal activity against Aspergillus niger ATCC 9029 | 2011 | Bioorganic & medicinal chemistry, May-01, Volume: 19, Issue:9
| Antifungal, cytotoxic and SAR studies of a series of N-alkyl, N-aryl and N-alkylphenyl-1,4-pyrrolediones and related compounds. |
| AID322163 | Antifungal activity against Candida krusei C 117-2000 after 48 hrs by CLSI M27-A2 method | 2008 | Bioorganic & medicinal chemistry, Jan-01, Volume: 16, Issue:1
| N-Phenyl and N-phenylalkyl-maleimides acting against Candida spp.: time-to-kill, stability, interaction with maleamic acids. |
| AID322162 | Antifungal activity against Candida coliculosa C 122-2000 after 48 hrs by CLSI M27-A2 method | 2008 | Bioorganic & medicinal chemistry, Jan-01, Volume: 16, Issue:1
| N-Phenyl and N-phenylalkyl-maleimides acting against Candida spp.: time-to-kill, stability, interaction with maleamic acids. |
| AID322159 | Antifungal activity against Candida glabrata C 115-2000 after 48 hrs by CLSI M27-A2 method | 2008 | Bioorganic & medicinal chemistry, Jan-01, Volume: 16, Issue:1
| N-Phenyl and N-phenylalkyl-maleimides acting against Candida spp.: time-to-kill, stability, interaction with maleamic acids. |
| AID322157 | Antifungal activity against Candida albicans C 129-2000 after 48 hrs by CLSI M27-A2 method | 2008 | Bioorganic & medicinal chemistry, Jan-01, Volume: 16, Issue:1
| N-Phenyl and N-phenylalkyl-maleimides acting against Candida spp.: time-to-kill, stability, interaction with maleamic acids. |
| AID322166 | Antifungal activity against Candida albicans ATCC 10231 within 90 mins by time-to-kill study | 2008 | Bioorganic & medicinal chemistry, Jan-01, Volume: 16, Issue:1
| N-Phenyl and N-phenylalkyl-maleimides acting against Candida spp.: time-to-kill, stability, interaction with maleamic acids. |
| AID322154 | Antifungal activity against Candida albicans C 126-2000 after 48 hrs by CLSI M27-A2 method | 2008 | Bioorganic & medicinal chemistry, Jan-01, Volume: 16, Issue:1
| N-Phenyl and N-phenylalkyl-maleimides acting against Candida spp.: time-to-kill, stability, interaction with maleamic acids. |
| AID596441 | Cytotoxicity against human SF268 cells assessed as cell growth after 2 days by sulforhodamine B assay | 2011 | Bioorganic & medicinal chemistry, May-01, Volume: 19, Issue:9
| Antifungal, cytotoxic and SAR studies of a series of N-alkyl, N-aryl and N-alkylphenyl-1,4-pyrrolediones and related compounds. |
| AID596445 | Antifungal activity against Saccharomyces cerevisiae ATCC 9763 | 2011 | Bioorganic & medicinal chemistry, May-01, Volume: 19, Issue:9
| Antifungal, cytotoxic and SAR studies of a series of N-alkyl, N-aryl and N-alkylphenyl-1,4-pyrrolediones and related compounds. |
| AID596527 | Antifungal activity against Microsporum gypseum C 115 2000 | 2011 | Bioorganic & medicinal chemistry, May-01, Volume: 19, Issue:9
| Antifungal, cytotoxic and SAR studies of a series of N-alkyl, N-aryl and N-alkylphenyl-1,4-pyrrolediones and related compounds. |
| AID322173 | Antifungal activity against Candida albicans ATCC 10231 pre-incubated for 6 days analysed after 24 hrs by CLSI M27-A2 method | 2008 | Bioorganic & medicinal chemistry, Jan-01, Volume: 16, Issue:1
| N-Phenyl and N-phenylalkyl-maleimides acting against Candida spp.: time-to-kill, stability, interaction with maleamic acids. |
| AID322164 | Antifungal activity against Candida kefyr C 123-2000 after 48 hrs by CLSI M27-A2 method | 2008 | Bioorganic & medicinal chemistry, Jan-01, Volume: 16, Issue:1
| N-Phenyl and N-phenylalkyl-maleimides acting against Candida spp.: time-to-kill, stability, interaction with maleamic acids. |
| AID1687062 | Inhibition of Escherichia coli MurA using UNAG and PEP as substrate preincubated for 30 mins in presence of UNAG followed by PEP addition and measured after 15 mins by malachite green colorimetric assay | 2018 | European journal of medicinal chemistry, Dec-05, Volume: 160 | A road map for prioritizing warheads for cysteine targeting covalent inhibitors. |
| AID596446 | Antifungal activity against Cryptococcus neoformans ATCC 32264 | 2011 | Bioorganic & medicinal chemistry, May-01, Volume: 19, Issue:9
| Antifungal, cytotoxic and SAR studies of a series of N-alkyl, N-aryl and N-alkylphenyl-1,4-pyrrolediones and related compounds. |
| AID322153 | Antifungal activity against Candida albicans C 125-2000 after 48 hrs by CLSI M27-A2 method | 2008 | Bioorganic & medicinal chemistry, Jan-01, Volume: 16, Issue:1
| N-Phenyl and N-phenylalkyl-maleimides acting against Candida spp.: time-to-kill, stability, interaction with maleamic acids. |
| AID322155 | Antifungal activity against Candida albicans C 127-2000 after 48 hrs by CLSI M27-A2 method | 2008 | Bioorganic & medicinal chemistry, Jan-01, Volume: 16, Issue:1
| N-Phenyl and N-phenylalkyl-maleimides acting against Candida spp.: time-to-kill, stability, interaction with maleamic acids. |
| AID1640019 | Luciferase/luciferin-expressing antifolate-resistant parasites were used to infect a culture of HepG2 cells that were pre-incubated with compounds. Infected hepatocytes emit light due to the luciferase reaction. Assay results are presented as the percent | 2018 | Science (New York, N.Y.), 12-07, Volume: 362, Issue:6419
| Open-source discovery of chemical leads for next-generation chemoprotective antimalarials. |
| AID439744 | Displacement of [3H]2-OG from human MGL by liquid scintillation counting | 2009 | Journal of medicinal chemistry, Dec-10, Volume: 52, Issue:23
| Synthesis and in vitro evaluation of N-substituted maleimide derivatives as selective monoglyceride lipase inhibitors. |
| AID596444 | Antifungal activity against Candida tropicalis C 131 2000 | 2011 | Bioorganic & medicinal chemistry, May-01, Volume: 19, Issue:9
| Antifungal, cytotoxic and SAR studies of a series of N-alkyl, N-aryl and N-alkylphenyl-1,4-pyrrolediones and related compounds. |
| AID596442 | Cytotoxicity against human erythrocytes assessed as hemolysis by spectrometric analysis | 2011 | Bioorganic & medicinal chemistry, May-01, Volume: 19, Issue:9
| Antifungal, cytotoxic and SAR studies of a series of N-alkyl, N-aryl and N-alkylphenyl-1,4-pyrrolediones and related compounds. |
| AID1687067 | Inhibition of recombinant cathepsin B (unknown origin) endopeptidase activity expressed in Escherichia coli assessed as residual activity at 100 uM using Z-RR-AMC as substrate preincubated for 30 mins under shaking in presence of 5 mM cysteine followed by | 2018 | European journal of medicinal chemistry, Dec-05, Volume: 160 | A road map for prioritizing warheads for cysteine targeting covalent inhibitors. |
| AID1687063 | Inhibition of Staphylococcus aureus MurA expressed in Escherichia coli using UNAG and PEP as substrate preincubated for 30 mins in presence of UNAG followed by PEP addition and measured after 15 mins by malachite green colorimetric assay | 2018 | European journal of medicinal chemistry, Dec-05, Volume: 160 | A road map for prioritizing warheads for cysteine targeting covalent inhibitors. |
| AID322171 | Antifungal activity against Candida albicans ATCC 10231 pre-incubated for 4 days analysed after 24 hrs by CLSI M27-A2 method | 2008 | Bioorganic & medicinal chemistry, Jan-01, Volume: 16, Issue:1
| N-Phenyl and N-phenylalkyl-maleimides acting against Candida spp.: time-to-kill, stability, interaction with maleamic acids. |
| AID439743 | Selectivity ratio of IC50 for human FAAH to IC50 for human MGL | 2009 | Journal of medicinal chemistry, Dec-10, Volume: 52, Issue:23
| Synthesis and in vitro evaluation of N-substituted maleimide derivatives as selective monoglyceride lipase inhibitors. |
| AID322174 | Antifungal activity against Candida albicans ATCC 10231 preincubated for 7 days analysed after 24 hrs by CLSI M27-A2 method | 2008 | Bioorganic & medicinal chemistry, Jan-01, Volume: 16, Issue:1
| N-Phenyl and N-phenylalkyl-maleimides acting against Candida spp.: time-to-kill, stability, interaction with maleamic acids. |
| AID322167 | Antifungal activity against Candida albicans ATCC 10231 after 24 hrs by CLSI M27-A2 method | 2008 | Bioorganic & medicinal chemistry, Jan-01, Volume: 16, Issue:1
| N-Phenyl and N-phenylalkyl-maleimides acting against Candida spp.: time-to-kill, stability, interaction with maleamic acids. |
| AID282721 | Inhibition of rabbit GSK3 | 2005 | Journal of medicinal chemistry, Nov-17, Volume: 48, Issue:23
| SAR and 3D-QSAR studies on thiadiazolidinone derivatives: exploration of structural requirements for glycogen synthase kinase 3 inhibitors. |
| AID322165 | Antifungal activity against Candida tropicalis C 137-1997 after 48 hrs by CLSI M27-A2 method | 2008 | Bioorganic & medicinal chemistry, Jan-01, Volume: 16, Issue:1
| N-Phenyl and N-phenylalkyl-maleimides acting against Candida spp.: time-to-kill, stability, interaction with maleamic acids. |
| AID322169 | Antifungal activity against Candida albicans ATCC 10231 pre-incubated for 2 days analysed after 24 hrs by CLSI M27-A2 method | 2008 | Bioorganic & medicinal chemistry, Jan-01, Volume: 16, Issue:1
| N-Phenyl and N-phenylalkyl-maleimides acting against Candida spp.: time-to-kill, stability, interaction with maleamic acids. |
| AID596525 | Antifungal activity against Aspergillus flavus ATCC 9170 | 2011 | Bioorganic & medicinal chemistry, May-01, Volume: 19, Issue:9
| Antifungal, cytotoxic and SAR studies of a series of N-alkyl, N-aryl and N-alkylphenyl-1,4-pyrrolediones and related compounds. |
| AID1687069 | Inhibition of recombinant cathepsin X (unknown origin) expressed in Pichia pastoris assessed as residual activity at 100 uM using Abz-Fek(Dnp)-OH as substrate preincubated for 30 mins under shaking in presence of 5 mM cysteine followed by substrate additi | 2018 | European journal of medicinal chemistry, Dec-05, Volume: 160 | A road map for prioritizing warheads for cysteine targeting covalent inhibitors. |
| AID596439 | Cytotoxicity against human MCF7 cells assessed as cell growth after 2 days by sulforhodamine B assay | 2011 | Bioorganic & medicinal chemistry, May-01, Volume: 19, Issue:9
| Antifungal, cytotoxic and SAR studies of a series of N-alkyl, N-aryl and N-alkylphenyl-1,4-pyrrolediones and related compounds. |
| AID1687068 | Inhibition of recombinant cathepsin B (unknown origin) exopeptidase activity expressed in Escherichia coli assessed as residual activity at 100 uM using Abz-GIVRAK(Dnp)-OH as substrate preincubated for 30 mins under shaking in presence of 5 mM cysteine fo | 2018 | European journal of medicinal chemistry, Dec-05, Volume: 160 | A road map for prioritizing warheads for cysteine targeting covalent inhibitors. |
| AID439745 | Displacement of [3H]ethanolamine from human recombinant FAAH by liquid scintillation counting | 2009 | Journal of medicinal chemistry, Dec-10, Volume: 52, Issue:23
| Synthesis and in vitro evaluation of N-substituted maleimide derivatives as selective monoglyceride lipase inhibitors. |
| AID596440 | Cytotoxicity against human H460 cells assessed as cell growth after 2 days by sulforhodamine B assay | 2011 | Bioorganic & medicinal chemistry, May-01, Volume: 19, Issue:9
| Antifungal, cytotoxic and SAR studies of a series of N-alkyl, N-aryl and N-alkylphenyl-1,4-pyrrolediones and related compounds. |
| AID322172 | Antifungal activity against Candida albicans ATCC 10231 pre-incubated for 5 days analysed after 24 hrs by CLSI M27-A2 method | 2008 | Bioorganic & medicinal chemistry, Jan-01, Volume: 16, Issue:1
| N-Phenyl and N-phenylalkyl-maleimides acting against Candida spp.: time-to-kill, stability, interaction with maleamic acids. |
| AID1796098 | Kinase Inhibition Assay from Article 10.1021/jm040895g: \\SAR and 3D-QSAR studies on thiadiazolidinone derivatives: exploration of structural requirements for glycogen synthase kinase 3 inhibitors.\\ | 2005 | Journal of medicinal chemistry, Nov-17, Volume: 48, Issue:23
| SAR and 3D-QSAR studies on thiadiazolidinone derivatives: exploration of structural requirements for glycogen synthase kinase 3 inhibitors. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |