| Assay ID | Title | Year | Journal | Article |
|---|
| AID466784 | Inhibition of VEGF-A-induced chemotaxis in HUVEC assessed as reduction in cell migration | 2010 | Journal of medicinal chemistry, Mar-11, Volume: 53, Issue:5
| Small molecule inhibitors of the neuropilin-1 vascular endothelial growth factor A (VEGF-A) interaction. |
| AID466785 | Cytotoxicity against human A549 cells after 48 hrs by XTT method | 2010 | Journal of medicinal chemistry, Mar-11, Volume: 53, Issue:5
| Small molecule inhibitors of the neuropilin-1 vascular endothelial growth factor A (VEGF-A) interaction. |
| AID466781 | Displacement of biotinylated-VEGF-A125 from human VEGFR2 expressed in human A549 cells | 2010 | Journal of medicinal chemistry, Mar-11, Volume: 53, Issue:5
| Small molecule inhibitors of the neuropilin-1 vascular endothelial growth factor A (VEGF-A) interaction. |
| AID466780 | Displacement of biotinylated-VEGF-A125 from human VEGFR1 expressed in human A549 cells | 2010 | Journal of medicinal chemistry, Mar-11, Volume: 53, Issue:5
| Small molecule inhibitors of the neuropilin-1 vascular endothelial growth factor A (VEGF-A) interaction. |
| AID466778 | Displacement of biotinylated-VEGF-A125 from human VEGFR1 expressed in human DU145 cells | 2010 | Journal of medicinal chemistry, Mar-11, Volume: 53, Issue:5
| Small molecule inhibitors of the neuropilin-1 vascular endothelial growth factor A (VEGF-A) interaction. |
| AID466783 | Inhibition of VEGF-A-induced VEGFR2 phosphorylation in HUVEC at 100 uM by ELISA | 2010 | Journal of medicinal chemistry, Mar-11, Volume: 53, Issue:5
| Small molecule inhibitors of the neuropilin-1 vascular endothelial growth factor A (VEGF-A) interaction. |
| AID466776 | Displacement of biotinylated-VEGF-A125 from human NRP1 expressed in human DU145 cells | 2010 | Journal of medicinal chemistry, Mar-11, Volume: 53, Issue:5
| Small molecule inhibitors of the neuropilin-1 vascular endothelial growth factor A (VEGF-A) interaction. |
| AID1650062 | Inhibition of recombinant human biotinylated VEGF-165A expressed in HEK293 cells binding to immobilized recombinant full length human FC-tagged NRP1 (chimera active) expressed in HEK293 cells at 11 uM using TMB as substrate incubated for 2 hrs followed by | 2020 | Bioorganic & medicinal chemistry, 01-01, Volume: 28, Issue:1
| Discovery of novel nonpeptide small-molecule NRP1 antagonists: Virtual screening, molecular simulation and structural modification. |
| AID466774 | Displacement of biotinylated-VEGF-A125 from NRP1 b1 domain by cell-free assay | 2010 | Journal of medicinal chemistry, Mar-11, Volume: 53, Issue:5
| Small molecule inhibitors of the neuropilin-1 vascular endothelial growth factor A (VEGF-A) interaction. |
| AID466773 | Displacement of [125I]VEGF-A from human NRP1 expressed in pig aortic endothelial cells | 2010 | Journal of medicinal chemistry, Mar-11, Volume: 53, Issue:5
| Small molecule inhibitors of the neuropilin-1 vascular endothelial growth factor A (VEGF-A) interaction. |
| AID466772 | Displacement of [125I]VEGF-A from human NRP1 expressed in pig aortic endothelial cells at 100 uM | 2010 | Journal of medicinal chemistry, Mar-11, Volume: 53, Issue:5
| Small molecule inhibitors of the neuropilin-1 vascular endothelial growth factor A (VEGF-A) interaction. |
| AID466782 | Inhibition of VEGF-A-induced VEGFR2 phosphorylation in HUVEC by ELISA | 2010 | Journal of medicinal chemistry, Mar-11, Volume: 53, Issue:5
| Small molecule inhibitors of the neuropilin-1 vascular endothelial growth factor A (VEGF-A) interaction. |
| AID1650065 | Inhibition of recombinant human biotinylated VEGF-165A expressed in HEK293 cells binding to FC-tagged VEGFR2 (unknown origin) using TMB as substrate incubated for 2 hrs followed by substrate addition by competitive ELISA | 2020 | Bioorganic & medicinal chemistry, 01-01, Volume: 28, Issue:1
| Discovery of novel nonpeptide small-molecule NRP1 antagonists: Virtual screening, molecular simulation and structural modification. |
| AID466779 | Displacement of biotinylated-VEGF-A125 from human VEGFR2 expressed in human DU145 cells | 2010 | Journal of medicinal chemistry, Mar-11, Volume: 53, Issue:5
| Small molecule inhibitors of the neuropilin-1 vascular endothelial growth factor A (VEGF-A) interaction. |
| AID1369557 | Half life in mouse at 2.5 mg/kg, iv | 2018 | Journal of medicinal chemistry, 05-10, Volume: 61, Issue:9
| Small Molecule Neuropilin-1 Antagonists Combine Antiangiogenic and Antitumor Activity with Immune Modulation through Reduction of Transforming Growth Factor Beta (TGFβ) Production in Regulatory T-Cells. |
| AID466777 | Displacement of biotinylated-VEGF-A125 from human NRP1 expressed in HUVEC | 2010 | Journal of medicinal chemistry, Mar-11, Volume: 53, Issue:5
| Small molecule inhibitors of the neuropilin-1 vascular endothelial growth factor A (VEGF-A) interaction. |
| AID1650060 | Inhibition of recombinant human biotinylated VEGF-165A expressed in HEK293 cells binding to immobilized recombinant full length human FC-tagged NRP1 (chimera active) expressed in HEK293 cells using TMB as substrate incubated for 2 hrs followed by substrat | 2020 | Bioorganic & medicinal chemistry, 01-01, Volume: 28, Issue:1
| Discovery of novel nonpeptide small-molecule NRP1 antagonists: Virtual screening, molecular simulation and structural modification. |
| AID466775 | Displacement of [125I]VEGF-A from human NRP1 expressed in human A549 cells | 2010 | Journal of medicinal chemistry, Mar-11, Volume: 53, Issue:5
| Small molecule inhibitors of the neuropilin-1 vascular endothelial growth factor A (VEGF-A) interaction. |
| AID1296008 | Cytotoxic Profiling of Annotated Libraries Using Quantitative High-Throughput Screening | 2020 | SLAS discovery : advancing life sciences R & D, 01, Volume: 25, Issue:1
| Cytotoxic Profiling of Annotated and Diverse Chemical Libraries Using Quantitative High-Throughput Screening. |
| AID1347159 | Primary screen GU Rhodamine qHTS for Zika virus inhibitors: Unlinked NS2B-NS3 protease assay | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1347160 | Primary screen NINDS Rhodamine qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1346986 | P-glycoprotein substrates identified in KB-3-1 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5
| A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
| AID1346987 | P-glycoprotein substrates identified in KB-8-5-11 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5
| A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |