| Assay ID | Title | Year | Journal | Article |
|---|
| AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1
| High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1
| High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1
| High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID504810 | Antagonists of the Thyroid Stimulating Hormone Receptor: HTS campaign | 2010 | Endocrinology, Jul, Volume: 151, Issue:7
| A small molecule inverse agonist for the human thyroid-stimulating hormone receptor. |
| AID504812 | Inverse Agonists of the Thyroid Stimulating Hormone Receptor: HTS campaign | 2010 | Endocrinology, Jul, Volume: 151, Issue:7
| A small molecule inverse agonist for the human thyroid-stimulating hormone receptor. |
| AID651635 | Viability Counterscreen for Primary qHTS for Inhibitors of ATXN expression | | | |
| AID23452 | Partition coefficient (logP) | 1987 | Journal of medicinal chemistry, Sep, Volume: 30, Issue:9
| 3-Carbonylacrylic derivatives as potential antimicrobial agents. Correlations between activity and reactivity toward cysteine. |
| AID1432751 | Inhibition of Sporosarcina pasteurii CCM 2056 urease assessed as reduction in ammonia production using urea as substrate measured for 120 mins by phenol-hypochlorite method | 2017 | Bioorganic & medicinal chemistry letters, 03-15, Volume: 27, Issue:6
| Potent covalent inhibitors of bacterial urease identified by activity-reactivity profiling. |
| AID1536845 | Antimycobacterial activity against Mycobacterium tuberculosis H37Rv ATCC 27294 after 4 days by microplate Alamar blue assay | 2019 | Bioorganic & medicinal chemistry letters, 02-15, Volume: 29, Issue:4
| Design, synthesis, and bioevaluation of a novel class of (E)-4-oxo-crotonamide derivatives as potent antituberculosis agents. |
| AID608238 | Antiproliferative activity against human HeLa cells assessed as inhibition of cell survival after 72 hrs by MTT method | 2011 | European journal of medicinal chemistry, Aug, Volume: 46, Issue:8
| Antiproliferative activity of aroylacrylic acids. Structure-activity study based on molecular interaction fields. |
| AID125801 | Antimicrobial activity against Microsporum canis(ATCC 11621) was determined | 1987 | Journal of medicinal chemistry, Sep, Volume: 30, Issue:9
| 3-Carbonylacrylic derivatives as potential antimicrobial agents. Correlations between activity and reactivity toward cysteine. |
| AID1432763 | Glutathione reactivity in pH 7.4 PBS measured after 6 to 36 hrs in presence of 1.375 mmol GSH by DTNB reagent based spectrophotometric method | 2017 | Bioorganic & medicinal chemistry letters, 03-15, Volume: 27, Issue:6
| Potent covalent inhibitors of bacterial urease identified by activity-reactivity profiling. |
| AID608239 | Antiproliferative activity against human LS 174T cells assessed as inhibition of cell survival after 72 hrs by MTT method | 2011 | European journal of medicinal chemistry, Aug, Volume: 46, Issue:8
| Antiproliferative activity of aroylacrylic acids. Structure-activity study based on molecular interaction fields. |
| AID207499 | Antimicrobial activity against Staphylococcus aureus(ATCC 6538) was determined | 1987 | Journal of medicinal chemistry, Sep, Volume: 30, Issue:9
| 3-Carbonylacrylic derivatives as potential antimicrobial agents. Correlations between activity and reactivity toward cysteine. |
| AID1432753 | Cytotoxicity against mouse BALB/3T3 cells assessed as inhibition of cell proliferation at 100 uM after 72 hrs by SRB assay relative to control | 2017 | Bioorganic & medicinal chemistry letters, 03-15, Volume: 27, Issue:6
| Potent covalent inhibitors of bacterial urease identified by activity-reactivity profiling. |
| AID210257 | Antimicrobial activity against Streptococcus pyogenes A(IVM P 134) was determined | 1987 | Journal of medicinal chemistry, Sep, Volume: 30, Issue:9
| 3-Carbonylacrylic derivatives as potential antimicrobial agents. Correlations between activity and reactivity toward cysteine. |
| AID1432760 | Inhibition of Sporosarcina pasteurii CCM 2056 urease assessed as reduction in ammonia production by measuring steady state enzyme-inhibitor complex using urea as substrate measured for 120 mins by phenol-hypochlorite method | 2017 | Bioorganic & medicinal chemistry letters, 03-15, Volume: 27, Issue:6
| Potent covalent inhibitors of bacterial urease identified by activity-reactivity profiling. |
| AID608240 | Antiproliferative activity against human K562 cells assessed as inhibition of cell survival after 72 hrs by MTT method | 2011 | European journal of medicinal chemistry, Aug, Volume: 46, Issue:8
| Antiproliferative activity of aroylacrylic acids. Structure-activity study based on molecular interaction fields. |
| AID1432759 | Inhibition of Sporosarcina pasteurii CCM 2056 urease assessed as reduction in ammonia production by measuring initial state enzyme-inhibitor complex using urea as substrate measured for 120 mins by phenol-hypochlorite method | 2017 | Bioorganic & medicinal chemistry letters, 03-15, Volume: 27, Issue:6
| Potent covalent inhibitors of bacterial urease identified by activity-reactivity profiling. |
| AID1432756 | Reversible inhibition of Sporosarcina pasteurii CCM 2056 urease assessed as reduction in ammonia production by measuring recovery of enzyme activity at 10 times IC50 preincubated for 60 mins followed by 100-fold dilution in to PBS containing urea as subst | 2017 | Bioorganic & medicinal chemistry letters, 03-15, Volume: 27, Issue:6
| Potent covalent inhibitors of bacterial urease identified by activity-reactivity profiling. |
| AID1432754 | Time-dependent Sporosarcina pasteurii CCM 2056 urease assessed as reduction in ammonia production using urea as substrate by phenol-hypochlorite method | 2017 | Bioorganic & medicinal chemistry letters, 03-15, Volume: 27, Issue:6
| Potent covalent inhibitors of bacterial urease identified by activity-reactivity profiling. |
| AID1432755 | Competitive inhibition of Sporosarcina pasteurii CCM 2056 urease assessed as reduction in ammonia production preincubated with enzyme followed by addition of varying levels of urea as substrate measured for 120 mins by Lineweaver-Burk plot analysis | 2017 | Bioorganic & medicinal chemistry letters, 03-15, Volume: 27, Issue:6
| Potent covalent inhibitors of bacterial urease identified by activity-reactivity profiling. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |