Page last updated: 2024-08-07 20:45:59

Immunoglobulin lambda variable 6-57

A protein that is a translation product of the IGLV6-57 gene in human. [PRO:DNx, UniProtKB:P01721]

Synonyms

Ig lambda chain V-VI region AR;
Ig lambda chain V-VI region EB4;
Ig lambda chain V-VI region NIG-48;
Ig lambda chain V-VI region SUT;
Ig lambda chain V-VI region WLT

Research

Bioassay Publications (1)

TimeframeStudies on this Protein(%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (100.00)2.80

Compounds (1)

Drugs with Activation Measurements

DrugTaxonomyMeasurementAverage (mM)Bioassay(s)Publication(s)
uvitex swnHomo sapiens (human)EC505.666723

Enables

This protein enables 1 target(s):

TargetCategoryDefinition
antigen bindingmolecular functionBinding to an antigen, any substance which is capable of inducing a specific immune response and of reacting with the products of that response, the specific antibody or specifically sensitized T-lymphocytes, or both. Binding may counteract the biological activity of the antigen. Antigen binding by an MHC protein complex allows the antigen to be displayed to a T cell or NK cell. [GOC:jl, ISBN:0198506732, ISBN:0721662544]

Located In

This protein is located in 2 target(s):

TargetCategoryDefinition
extracellular regioncellular componentThe space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite. [GOC:go_curators]
plasma membranecellular componentThe membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. [ISBN:0716731363]

Active In

This protein is active in 1 target(s):

TargetCategoryDefinition
extracellular spacecellular componentThat part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid. [ISBN:0198547684]

Part Of

This protein is part of 1 target(s):

TargetCategoryDefinition
immunoglobulin complexcellular componentA protein complex that in its canonical form is composed of two identical immunoglobulin heavy chains and two identical immunoglobulin light chains, held together by disulfide bonds and sometimes complexed with additional proteins. An immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph. [GOC:add, GOC:jl, ISBN:0781765196]

Involved In

This protein is involved in 3 target(s):

TargetCategoryDefinition
adaptive immune responsebiological processAn immune response mediated by cells expressing specific receptors for antigens produced through a somatic diversification process, and allowing for an enhanced secondary response to subsequent exposures to the same antigen (immunological memory). [GO_REF:0000022, GOC:add, ISBN:0781735149]
immune responsebiological processAny immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat. [GO_REF:0000022, GOC:add]
immunoglobulin productionbiological processThe appearance of immunoglobulin due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. [GOC:add, ISBN:0781735149]