| AID1802637 | Ecto-5'-Nucleotidase Inhibition Assay from Article 10.1111/cbdd.12861: \\Isonicotinohydrazones as inhibitors of alkaline phosphatase and ecto-5'-nucleotidase.\\ | 2017 | Chemical biology & drug design, 03, Volume: 89, Issue:3
| Isonicotinohydrazones as inhibitors of alkaline phosphatase and ecto-5'-nucleotidase. |
| AID1802638 | Alkaline Phosphatase Inhibition Assay from Article 10.1111/cbdd.12861: \\Isonicotinohydrazones as inhibitors of alkaline phosphatase and ecto-5'-nucleotidase.\\ | 2017 | Chemical biology & drug design, 03, Volume: 89, Issue:3
| Isonicotinohydrazones as inhibitors of alkaline phosphatase and ecto-5'-nucleotidase. |
| AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1
| High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1
| High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID651635 | Viability Counterscreen for Primary qHTS for Inhibitors of ATXN expression | | | |
| AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1
| High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID504810 | Antagonists of the Thyroid Stimulating Hormone Receptor: HTS campaign | 2010 | Endocrinology, Jul, Volume: 151, Issue:7
| A small molecule inverse agonist for the human thyroid-stimulating hormone receptor. |
| AID1745845 | Primary qHTS for Inhibitors of ATXN expression | | | |
| AID504812 | Inverse Agonists of the Thyroid Stimulating Hormone Receptor: HTS campaign | 2010 | Endocrinology, Jul, Volume: 151, Issue:7
| A small molecule inverse agonist for the human thyroid-stimulating hormone receptor. |
| AID1416257 | Antimycobacterial activity against rifampicin-resistant Mycobacterium tuberculosis H37Rv by resazurin dye based fluorimetric method | 2017 | MedChemComm, Jun-01, Volume: 8, Issue:6
| Benzylsulfanyl benzo-heterocycle amides and hydrazones as new agents against drug-susceptible and resistant |
| AID1668218 | Antioxidant activity assessed as DPPH radical scavenging activity at 100 uM after 30 mins (Rvb = 1.9 +/- 1.2%) | 2020 | Bioorganic & medicinal chemistry, 05-15, Volume: 28, Issue:10
| Acylhydrazones as isoniazid derivatives with multi-target profiles for the treatment of Alzheimer's disease: Radical scavenging, myeloperoxidase/acetylcholinesterase inhibition and biometal chelation. |
| AID1416256 | Antimycobacterial activity against streptomycin-resistant Mycobacterium tuberculosis ATCC 35820 by resazurin dye based fluorimetric method | 2017 | MedChemComm, Jun-01, Volume: 8, Issue:6
| Benzylsulfanyl benzo-heterocycle amides and hydrazones as new agents against drug-susceptible and resistant |
| AID1416264 | Cytotoxicity against African green monkey Vero cells assessed as cell viability at 0.625 ug/ml after 72 hrs by CCK8 assay (Rvb = 100%) | 2017 | MedChemComm, Jun-01, Volume: 8, Issue:6
| Benzylsulfanyl benzo-heterocycle amides and hydrazones as new agents against drug-susceptible and resistant |
| AID1416265 | Cytotoxicity against African green monkey Vero cells assessed as cell viability at 1.25 ug/ml after 72 hrs by CCK8 assay (Rvb = 100%) | 2017 | MedChemComm, Jun-01, Volume: 8, Issue:6
| Benzylsulfanyl benzo-heterocycle amides and hydrazones as new agents against drug-susceptible and resistant |
| AID1416268 | Cytotoxicity against African green monkey Vero cells assessed as cell viability at 10 ug/ml after 72 hrs by CCK8 assay (Rvb = 100%) | 2017 | MedChemComm, Jun-01, Volume: 8, Issue:6
| Benzylsulfanyl benzo-heterocycle amides and hydrazones as new agents against drug-susceptible and resistant |
| AID1179731 | Cytoprotection in mouse CRL2181 cells assessed as reduction in UV-oxidized LDL-induced cytotoxicity by measuring cell viability at 1 uM after 24 hrs by MTT assay relative to untreated control | 2014 | Bioorganic & medicinal chemistry, Aug-01, Volume: 22, Issue:15
| Synthesis, antioxidant and cytoprotective evaluation of potential antiatherogenic phenolic hydrazones. A structure-activity relationship insight. |
| AID1416254 | Antimycobacterial activity against kanamycin-resistant Mycobacterium tuberculosis ATCC 35827 by resazurin dye based fluorimetric method | 2017 | MedChemComm, Jun-01, Volume: 8, Issue:6
| Benzylsulfanyl benzo-heterocycle amides and hydrazones as new agents against drug-susceptible and resistant |
| AID1416263 | Cytotoxicity against African green monkey Vero cells assessed as cell viability at 0.312 ug/ml after 72 hrs by CCK8 assay (Rvb = 100%) | 2017 | MedChemComm, Jun-01, Volume: 8, Issue:6
| Benzylsulfanyl benzo-heterocycle amides and hydrazones as new agents against drug-susceptible and resistant |
| AID1179730 | Cytoprotection in mouse CRL2181 cells assessed as reduction in UV-oxidized LDL-induced cytotoxicity by measuring cell viability at 10 uM after 24 hrs by MTT assay relative to untreated control | 2014 | Bioorganic & medicinal chemistry, Aug-01, Volume: 22, Issue:15
| Synthesis, antioxidant and cytoprotective evaluation of potential antiatherogenic phenolic hydrazones. A structure-activity relationship insight. |
| AID1416252 | Antimycobacterial activity against ethambutol-resistant Mycobacterium tuberculosis ATCC 35837 by resazurin dye based fluorimetric method | 2017 | MedChemComm, Jun-01, Volume: 8, Issue:6
| Benzylsulfanyl benzo-heterocycle amides and hydrazones as new agents against drug-susceptible and resistant |
| AID1668220 | Inhibition of rat bone marrow myeloperoxidase using H2O2 as substrate at 10 uM after 20 mins by TMB based method (Rvb = - 1.4 +/- 12.7%) | 2020 | Bioorganic & medicinal chemistry, 05-15, Volume: 28, Issue:10
| Acylhydrazones as isoniazid derivatives with multi-target profiles for the treatment of Alzheimer's disease: Radical scavenging, myeloperoxidase/acetylcholinesterase inhibition and biometal chelation. |
| AID1416247 | Antimycobacterial activity against drug-susceptible Mycobacterium tuberculosis clinical isolate | 2017 | MedChemComm, Jun-01, Volume: 8, Issue:6
| Benzylsulfanyl benzo-heterocycle amides and hydrazones as new agents against drug-susceptible and resistant |
| AID1416255 | Antimycobacterial activity against p-aminosalicyclic acid-resistant Mycobacterium tuberculosis ATCC 35821 by resazurin dye based fluorimetric method | 2017 | MedChemComm, Jun-01, Volume: 8, Issue:6
| Benzylsulfanyl benzo-heterocycle amides and hydrazones as new agents against drug-susceptible and resistant |
| AID1416262 | Cytotoxicity against African green monkey Vero cells assessed as cell viability at 0.156 ug/ml after 72 hrs by CCK8 assay (Rvb = 100%) | 2017 | MedChemComm, Jun-01, Volume: 8, Issue:6
| Benzylsulfanyl benzo-heterocycle amides and hydrazones as new agents against drug-susceptible and resistant |
| AID1416269 | Cytotoxicity against African green monkey Vero cells assessed as cell viability at 20 ug/ml after 72 hrs by CCK8 assay (Rvb = 100%) | 2017 | MedChemComm, Jun-01, Volume: 8, Issue:6
| Benzylsulfanyl benzo-heterocycle amides and hydrazones as new agents against drug-susceptible and resistant |
| AID1179729 | Antioxidant activity assessed as reduction in mouse CRL2181 cells-mediated human LDL oxidation by measuring TBARS level at 1 uM after 18 hrs | 2014 | Bioorganic & medicinal chemistry, Aug-01, Volume: 22, Issue:15
| Synthesis, antioxidant and cytoprotective evaluation of potential antiatherogenic phenolic hydrazones. A structure-activity relationship insight. |
| AID1668219 | Antioxidant activity assessed as DPPH radical scavenging activity after 30 mins | 2020 | Bioorganic & medicinal chemistry, 05-15, Volume: 28, Issue:10
| Acylhydrazones as isoniazid derivatives with multi-target profiles for the treatment of Alzheimer's disease: Radical scavenging, myeloperoxidase/acetylcholinesterase inhibition and biometal chelation. |
| AID1416248 | Antimycobacterial activity against multidrug-resistant Mycobacterium tuberculosis clinical isolate | 2017 | MedChemComm, Jun-01, Volume: 8, Issue:6
| Benzylsulfanyl benzo-heterocycle amides and hydrazones as new agents against drug-susceptible and resistant |
| AID1337098 | Inhibition of human MPO assessed as residual activity in absence of H2O | 2017 | ACS medicinal chemistry letters, Feb-09, Volume: 8, Issue:2
| From Dynamic Combinatorial Chemistry to |
| AID1337095 | Inhibition of human MPO | 2017 | ACS medicinal chemistry letters, Feb-09, Volume: 8, Issue:2
| From Dynamic Combinatorial Chemistry to |
| AID1416253 | Antimycobacterial activity against ethionamide-resistant Mycobacterium tuberculosis ATCC 35830 by resazurin dye based fluorimetric method | 2017 | MedChemComm, Jun-01, Volume: 8, Issue:6
| Benzylsulfanyl benzo-heterocycle amides and hydrazones as new agents against drug-susceptible and resistant |
| AID1179728 | Antioxidant activity assessed as reduction in mouse CRL2181 cells-mediated human LDL oxidation by measuring TBARS level at 10 uM after 18 hrs | 2014 | Bioorganic & medicinal chemistry, Aug-01, Volume: 22, Issue:15
| Synthesis, antioxidant and cytoprotective evaluation of potential antiatherogenic phenolic hydrazones. A structure-activity relationship insight. |
| AID1668222 | Inhibition of Electrophorus electricus AChE at 100 uM using acetylthiocholine iodide as substrate preincubated for 30 mins followed by substrate addition and measured after 10 mins by Ellman's method (Rvb = 7 +/- 7.1%) | 2020 | Bioorganic & medicinal chemistry, 05-15, Volume: 28, Issue:10
| Acylhydrazones as isoniazid derivatives with multi-target profiles for the treatment of Alzheimer's disease: Radical scavenging, myeloperoxidase/acetylcholinesterase inhibition and biometal chelation. |
| AID1668221 | Inhibition of rat bone marrow myeloperoxidase using H2O2 as substrate after 20 mins by TMB based method | 2020 | Bioorganic & medicinal chemistry, 05-15, Volume: 28, Issue:10
| Acylhydrazones as isoniazid derivatives with multi-target profiles for the treatment of Alzheimer's disease: Radical scavenging, myeloperoxidase/acetylcholinesterase inhibition and biometal chelation. |
| AID1416267 | Cytotoxicity against African green monkey Vero cells assessed as cell viability at 5 ug/ml after 72 hrs by CCK8 assay (Rvb = 100%) | 2017 | MedChemComm, Jun-01, Volume: 8, Issue:6
| Benzylsulfanyl benzo-heterocycle amides and hydrazones as new agents against drug-susceptible and resistant |
| AID1416260 | Cytotoxicity against African green monkey Vero cells assessed as cell viability at 0.039 ug/ml after 72 hrs by CCK8 assay (Rvb = 100%) | 2017 | MedChemComm, Jun-01, Volume: 8, Issue:6
| Benzylsulfanyl benzo-heterocycle amides and hydrazones as new agents against drug-susceptible and resistant |
| AID1416259 | Cytotoxicity against African green monkey Vero cells assessed as cell viability at 0.02 ug/ml after 72 hrs by CCK8 assay (Rvb = 100%) | 2017 | MedChemComm, Jun-01, Volume: 8, Issue:6
| Benzylsulfanyl benzo-heterocycle amides and hydrazones as new agents against drug-susceptible and resistant |
| AID1416261 | Cytotoxicity against African green monkey Vero cells assessed as cell viability at 0.078 ug/ml after 72 hrs by CCK8 assay (Rvb = 100%) | 2017 | MedChemComm, Jun-01, Volume: 8, Issue:6
| Benzylsulfanyl benzo-heterocycle amides and hydrazones as new agents against drug-susceptible and resistant |
| AID1416258 | Cytotoxicity against African green monkey Vero cells assessed as cell viability at 0.01 ug/ml after 72 hrs by CCK8 assay (Rvb = 100%) | 2017 | MedChemComm, Jun-01, Volume: 8, Issue:6
| Benzylsulfanyl benzo-heterocycle amides and hydrazones as new agents against drug-susceptible and resistant |
| AID1416249 | Antimycobacterial activity against extensively drug-resistant Mycobacterium tuberculosis clinical isolate | 2017 | MedChemComm, Jun-01, Volume: 8, Issue:6
| Benzylsulfanyl benzo-heterocycle amides and hydrazones as new agents against drug-susceptible and resistant |
| AID1422878 | Binding affinity to recombinant Trypanosoma cruzi His/haemaglutinin-tagged BDF3 expressed in Escherichia coli BL21 assessed as compound amplification factor at 75 uM by LC-MS based dynamic combinatorial chemistry analysis | 2018 | ACS medicinal chemistry letters, Oct-11, Volume: 9, Issue:10
| Discovery of a Biologically Active Bromodomain Inhibitor by Target-Directed Dynamic Combinatorial Chemistry. |
| AID1337097 | Inhibition of human MPO assessed as residual activity in presence of H2O2 | 2017 | ACS medicinal chemistry letters, Feb-09, Volume: 8, Issue:2
| From Dynamic Combinatorial Chemistry to |
| AID1416266 | Cytotoxicity against African green monkey Vero cells assessed as cell viability at 2.5 ug/ml after 72 hrs by CCK8 assay (Rvb = 100%) | 2017 | MedChemComm, Jun-01, Volume: 8, Issue:6
| Benzylsulfanyl benzo-heterocycle amides and hydrazones as new agents against drug-susceptible and resistant |
| AID1179727 | Antioxidant activity assessed as DPPH radical scavenging activity by UV-Visible spectrophotometry | 2014 | Bioorganic & medicinal chemistry, Aug-01, Volume: 22, Issue:15
| Synthesis, antioxidant and cytoprotective evaluation of potential antiatherogenic phenolic hydrazones. A structure-activity relationship insight. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |