| Assay ID | Title | Year | Journal | Article |
|---|
| AID1347159 | Primary screen GU Rhodamine qHTS for Zika virus inhibitors: Unlinked NS2B-NS3 protease assay | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1296008 | Cytotoxic Profiling of Annotated Libraries Using Quantitative High-Throughput Screening | 2020 | SLAS discovery : advancing life sciences R & D, 01, Volume: 25, Issue:1
| Cytotoxic Profiling of Annotated and Diverse Chemical Libraries Using Quantitative High-Throughput Screening. |
| AID1347160 | Primary screen NINDS Rhodamine qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1346986 | P-glycoprotein substrates identified in KB-3-1 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5
| A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
| AID1346987 | P-glycoprotein substrates identified in KB-8-5-11 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5
| A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
| AID238971 | Inhibition of [125I]IABN binding to human Dopamine D2L receptor expressed in HEK 293 cells | 2005 | Journal of medicinal chemistry, Jun-02, Volume: 48, Issue:11
| Dopamine D3 receptor partial agonists and antagonists as potential drug abuse therapeutic agents. |
| AID597450 | Displacement of [125I]-IABN from human dopamine D4 receptor expressed in HEK293 cells after 60 mins by gamma counting | 2011 | Journal of medicinal chemistry, May-26, Volume: 54, Issue:10
| N-(3-fluoro-4-(4-(2-methoxy or 2,3-dichlorophenyl)piperazine-1-yl)butyl)arylcarboxamides as selective dopamine D3 receptor ligands: critical role of the carboxamide linker for D3 receptor selectivity. |
| AID297335 | Antagonist activity at human dopamine D2 receptor expressed in HEK293 cells by mitogenesis assay | 2007 | Journal of medicinal chemistry, Aug-23, Volume: 50, Issue:17
| Heterocyclic analogues of N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butyl)arylcarboxamides with functionalized linking chains as novel dopamine D3 receptor ligands: potential substance abuse therapeutic agents. |
| AID297333 | Selectivity for human dopamine D3 receptor over human dopamine D2 receptor | 2007 | Journal of medicinal chemistry, Aug-23, Volume: 50, Issue:17
| Heterocyclic analogues of N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butyl)arylcarboxamides with functionalized linking chains as novel dopamine D3 receptor ligands: potential substance abuse therapeutic agents. |
| AID597451 | Displacement of [125I]-IABN from human dopamine D2L receptor expressed in HEK293 cells after 60 mins by gamma counting | 2011 | Journal of medicinal chemistry, May-26, Volume: 54, Issue:10
| N-(3-fluoro-4-(4-(2-methoxy or 2,3-dichlorophenyl)piperazine-1-yl)butyl)arylcarboxamides as selective dopamine D3 receptor ligands: critical role of the carboxamide linker for D3 receptor selectivity. |
| AID597449 | Selectivity ratio Ki for human dopamine D4 receptor to Ki for human dopamine D3 receptor | 2011 | Journal of medicinal chemistry, May-26, Volume: 54, Issue:10
| N-(3-fluoro-4-(4-(2-methoxy or 2,3-dichlorophenyl)piperazine-1-yl)butyl)arylcarboxamides as selective dopamine D3 receptor ligands: critical role of the carboxamide linker for D3 receptor selectivity. |
| AID297342 | Selectivity for human dopamine D3 receptor over human 5HT1A receptor | 2007 | Journal of medicinal chemistry, Aug-23, Volume: 50, Issue:17
| Heterocyclic analogues of N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butyl)arylcarboxamides with functionalized linking chains as novel dopamine D3 receptor ligands: potential substance abuse therapeutic agents. |
| AID238486 | Binding affinity for human dopamine D4 receptor | 2005 | Journal of medicinal chemistry, Feb-10, Volume: 48, Issue:3
| Novel heterocyclic trans olefin analogues of N-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl}arylcarboxamides as selective probes with high affinity for the dopamine D3 receptor. |
| AID297341 | Binding affinity to human 5HT2C receptor | 2007 | Journal of medicinal chemistry, Aug-23, Volume: 50, Issue:17
| Heterocyclic analogues of N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butyl)arylcarboxamides with functionalized linking chains as novel dopamine D3 receptor ligands: potential substance abuse therapeutic agents. |
| AID243087 | Relative binding affinity for human dopamine D4 and dopamine D3 receptors | 2005 | Journal of medicinal chemistry, Feb-10, Volume: 48, Issue:3
| Novel heterocyclic trans olefin analogues of N-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl}arylcarboxamides as selective probes with high affinity for the dopamine D3 receptor. |
| AID297330 | Displacement of [125I]IABN from human dopamine D2 receptor expressed in HEK293 cells | 2007 | Journal of medicinal chemistry, Aug-23, Volume: 50, Issue:17
| Heterocyclic analogues of N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butyl)arylcarboxamides with functionalized linking chains as novel dopamine D3 receptor ligands: potential substance abuse therapeutic agents. |
| AID238642 | Binding affinity for human dopamine D2 receptor | 2005 | Journal of medicinal chemistry, Feb-10, Volume: 48, Issue:3
| Novel heterocyclic trans olefin analogues of N-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl}arylcarboxamides as selective probes with high affinity for the dopamine D3 receptor. |
| AID238643 | Binding affinity for human dopamine D3 receptor | 2005 | Journal of medicinal chemistry, Feb-10, Volume: 48, Issue:3
| Novel heterocyclic trans olefin analogues of N-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl}arylcarboxamides as selective probes with high affinity for the dopamine D3 receptor. |
| AID249398 | Dopamine receptor D2/D3 selectivity ratio from in vitro functional assays | 2005 | Journal of medicinal chemistry, Jun-02, Volume: 48, Issue:11
| Dopamine D3 receptor partial agonists and antagonists as potential drug abuse therapeutic agents. |
| AID238950 | Inhibition of [125I]IABN binding to human Dopamine D4 receptor expressed in HEK 293 cells | 2005 | Journal of medicinal chemistry, Jun-02, Volume: 48, Issue:11
| Dopamine D3 receptor partial agonists and antagonists as potential drug abuse therapeutic agents. |
| AID1232331 | Selectivity index, ratio of Ki for human dopamine D4 receptor to KI for human dopamine D3 receptor | 2015 | Journal of medicinal chemistry, Jul-23, Volume: 58, Issue:14
| Identifying Medication Targets for Psychostimulant Addiction: Unraveling the Dopamine D3 Receptor Hypothesis. |
| AID297343 | Selectivity for human dopamine D3 receptor over human 5HT2A receptor | 2007 | Journal of medicinal chemistry, Aug-23, Volume: 50, Issue:17
| Heterocyclic analogues of N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butyl)arylcarboxamides with functionalized linking chains as novel dopamine D3 receptor ligands: potential substance abuse therapeutic agents. |
| AID238947 | Inhibition of [3H]YM-09151-2 binding to human Dopamine D3 receptor expressed in CHO cells | 2005 | Journal of medicinal chemistry, Jun-02, Volume: 48, Issue:11
| Dopamine D3 receptor partial agonists and antagonists as potential drug abuse therapeutic agents. |
| AID1232327 | Displacement of [3H]N-methylspiperone from human dopamine D2 receptor expressed in HEK293 cells | 2015 | Journal of medicinal chemistry, Jul-23, Volume: 58, Issue:14
| Identifying Medication Targets for Psychostimulant Addiction: Unraveling the Dopamine D3 Receptor Hypothesis. |
| AID297339 | Binding affinity to human 5HT1A receptor | 2007 | Journal of medicinal chemistry, Aug-23, Volume: 50, Issue:17
| Heterocyclic analogues of N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butyl)arylcarboxamides with functionalized linking chains as novel dopamine D3 receptor ligands: potential substance abuse therapeutic agents. |
| AID1232329 | Displacement of [3H]N-methylspiperone from human dopamine D4 receptor expressed in HEK293 cells | 2015 | Journal of medicinal chemistry, Jul-23, Volume: 58, Issue:14
| Identifying Medication Targets for Psychostimulant Addiction: Unraveling the Dopamine D3 Receptor Hypothesis. |
| AID297334 | Selectivity for human dopamine D3 receptor over human dopamine D4 receptor | 2007 | Journal of medicinal chemistry, Aug-23, Volume: 50, Issue:17
| Heterocyclic analogues of N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butyl)arylcarboxamides with functionalized linking chains as novel dopamine D3 receptor ligands: potential substance abuse therapeutic agents. |
| AID248805 | Mitogenic stimulation or antagonism of 30 nM quinpirole-stimulated mitogenesis in CHO cells expressing human dopamine D2 receptor | 2005 | Journal of medicinal chemistry, Jun-02, Volume: 48, Issue:11
| Dopamine D3 receptor partial agonists and antagonists as potential drug abuse therapeutic agents. |
| AID246572 | Inhibition of quinpirole stimulation of mitogenesis at human dopamine D2 receptors expressed in Chinese hamster ovary cells | 2005 | Journal of medicinal chemistry, Feb-10, Volume: 48, Issue:3
| Novel heterocyclic trans olefin analogues of N-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl}arylcarboxamides as selective probes with high affinity for the dopamine D3 receptor. |
| AID237455 | cLogD was determined | 2005 | Journal of medicinal chemistry, Jun-02, Volume: 48, Issue:11
| Dopamine D3 receptor partial agonists and antagonists as potential drug abuse therapeutic agents. |
| AID597447 | Displacement of [125I]-IABN from human dopamine D3 receptor expressed in HEK293 cells after 60 mins by gamma counting | 2011 | Journal of medicinal chemistry, May-26, Volume: 54, Issue:10
| N-(3-fluoro-4-(4-(2-methoxy or 2,3-dichlorophenyl)piperazine-1-yl)butyl)arylcarboxamides as selective dopamine D3 receptor ligands: critical role of the carboxamide linker for D3 receptor selectivity. |
| AID248806 | Mitogenic stimulation or antagonism of 30 nM quinpirole-stimulated mitogenesis in CHO cells expressing human dopamine D3 receptor | 2005 | Journal of medicinal chemistry, Jun-02, Volume: 48, Issue:11
| Dopamine D3 receptor partial agonists and antagonists as potential drug abuse therapeutic agents. |
| AID238970 | Inhibition of [3H]YM-09151-2 binding to human Dopamine D2L receptor expressed in CHO cells | 2005 | Journal of medicinal chemistry, Jun-02, Volume: 48, Issue:11
| Dopamine D3 receptor partial agonists and antagonists as potential drug abuse therapeutic agents. |
| AID597448 | Selectivity ratio Ki for human dopamine D2L receptor to Ki for human dopamine D3 receptor | 2011 | Journal of medicinal chemistry, May-26, Volume: 54, Issue:10
| N-(3-fluoro-4-(4-(2-methoxy or 2,3-dichlorophenyl)piperazine-1-yl)butyl)arylcarboxamides as selective dopamine D3 receptor ligands: critical role of the carboxamide linker for D3 receptor selectivity. |
| AID243111 | Relative binding affinity for human dopamine D2 and D3 receptors | 2005 | Journal of medicinal chemistry, Feb-10, Volume: 48, Issue:3
| Novel heterocyclic trans olefin analogues of N-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl}arylcarboxamides as selective probes with high affinity for the dopamine D3 receptor. |
| AID297344 | Selectivity for human dopamine D3 receptor over human 5HT2C receptor | 2007 | Journal of medicinal chemistry, Aug-23, Volume: 50, Issue:17
| Heterocyclic analogues of N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butyl)arylcarboxamides with functionalized linking chains as novel dopamine D3 receptor ligands: potential substance abuse therapeutic agents. |
| AID688180 | Selectivity ratio of dopamine D1 like receptor to dopamine D3 receptor | 2012 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 22, Issue:17
| High-affinity and selective dopamine D₃ receptor full agonists. |
| AID243003 | Ratio of binding affinity at dopamine D2L over D3 receptors | 2005 | Journal of medicinal chemistry, Jun-02, Volume: 48, Issue:11
| Dopamine D3 receptor partial agonists and antagonists as potential drug abuse therapeutic agents. |
| AID249049 | Compound tested for locomotor activity in male Swiss-Webster mice (n=8) | 2005 | Journal of medicinal chemistry, Jun-02, Volume: 48, Issue:11
| Dopamine D3 receptor partial agonists and antagonists as potential drug abuse therapeutic agents. |
| AID249434 | Relative inhibition of quinpirole stimulation at human dopamine D2 and D3 receptor expressed in CHO cells | 2005 | Journal of medicinal chemistry, Feb-10, Volume: 48, Issue:3
| Novel heterocyclic trans olefin analogues of N-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl}arylcarboxamides as selective probes with high affinity for the dopamine D3 receptor. |
| AID1232330 | Selectivity index, ratio of Ki for human dopamine D2 receptor to KI for human dopamine D3 receptor | 2015 | Journal of medicinal chemistry, Jul-23, Volume: 58, Issue:14
| Identifying Medication Targets for Psychostimulant Addiction: Unraveling the Dopamine D3 Receptor Hypothesis. |
| AID688179 | Selectivity ratio of dopamine D2 receptor to dopamine D3 receptor | 2012 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 22, Issue:17
| High-affinity and selective dopamine D₃ receptor full agonists. |
| AID297336 | Antagonist activity at human dopamine D3 receptor expressed in HEK293 cells by mitogenesis assay | 2007 | Journal of medicinal chemistry, Aug-23, Volume: 50, Issue:17
| Heterocyclic analogues of N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butyl)arylcarboxamides with functionalized linking chains as novel dopamine D3 receptor ligands: potential substance abuse therapeutic agents. |
| AID238948 | Inhibition of [125I]IABN binding to human Dopamine D3 receptor expressed in HEK 293 cells | 2005 | Journal of medicinal chemistry, Jun-02, Volume: 48, Issue:11
| Dopamine D3 receptor partial agonists and antagonists as potential drug abuse therapeutic agents. |
| AID237570 | Lipophilicity was determined | 2005 | Journal of medicinal chemistry, Feb-10, Volume: 48, Issue:3
| Novel heterocyclic trans olefin analogues of N-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl}arylcarboxamides as selective probes with high affinity for the dopamine D3 receptor. |
| AID1232328 | Displacement of [3H]N-methylspiperone from human dopamine D3 receptor expressed in HEK293 cells | 2015 | Journal of medicinal chemistry, Jul-23, Volume: 58, Issue:14
| Identifying Medication Targets for Psychostimulant Addiction: Unraveling the Dopamine D3 Receptor Hypothesis. |
| AID297340 | Binding affinity to human 5HT2A receptor | 2007 | Journal of medicinal chemistry, Aug-23, Volume: 50, Issue:17
| Heterocyclic analogues of N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butyl)arylcarboxamides with functionalized linking chains as novel dopamine D3 receptor ligands: potential substance abuse therapeutic agents. |
| AID246573 | Inhibition of quinpirole stimulation of mitogenesis at human dopamine D3 receptors expressed in Chinese hamster ovary cells | 2005 | Journal of medicinal chemistry, Feb-10, Volume: 48, Issue:3
| Novel heterocyclic trans olefin analogues of N-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl}arylcarboxamides as selective probes with high affinity for the dopamine D3 receptor. |
| AID297332 | Displacement of [125I]IABN from human dopamine D4 receptor expressed in HEK293 cells | 2007 | Journal of medicinal chemistry, Aug-23, Volume: 50, Issue:17
| Heterocyclic analogues of N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butyl)arylcarboxamides with functionalized linking chains as novel dopamine D3 receptor ligands: potential substance abuse therapeutic agents. |
| AID297331 | Displacement of [125I]IABN from human dopamine D3 receptor expressed in HEK293 cells | 2007 | Journal of medicinal chemistry, Aug-23, Volume: 50, Issue:17
| Heterocyclic analogues of N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butyl)arylcarboxamides with functionalized linking chains as novel dopamine D3 receptor ligands: potential substance abuse therapeutic agents. |
| AID1345833 | Human D3 receptor (Dopamine receptors) | 2007 | Journal of medicinal chemistry, Aug-23, Volume: 50, Issue:17
| Heterocyclic analogues of N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butyl)arylcarboxamides with functionalized linking chains as novel dopamine D3 receptor ligands: potential substance abuse therapeutic agents. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |