fluphenacur profile

Fluphenacur is a synthetic compound belonging to the phenothiazine class of drugs. It was initially developed as a potential antipsychotic, but research showed that it also exhibits significant analgesic effects, particularly in the context of neuropathic pain. Fluphenacur is notable for its unique mechanism of action that involves modulation of both dopamine and serotonin receptors, as well as inhibition of certain ion channels. This multi-target profile contributes to its pain-relieving properties and suggests potential applications in treating various forms of chronic pain. Fluphenacur is currently undergoing preclinical studies to assess its therapeutic potential and safety profile for various pain conditions.'

fluphenacur: RN given refers to parent cpd [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

ID Source	ID
PubMed CID	71777
CHEMBL ID	1364906
CHEBI ID	39384
SCHEMBL ID	27105
MeSH ID	M0191651

Synonym
BRD-A71774530-001-01-8
103055-07-8
n-[[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]carbamoyl]-2,6-difluoro-benzamide
1-(2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl)-3-(2,6-difluorobenzoyl)urea
lufenuron
BSPBIO_002424
n-{[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]carbamoyl}-2,6-difluorobenzamide
fluphenacur
n-({[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]amino}carbonyl)-2,6-difluorobenzamide
CHEBI:39384 ,
NCGC00095978-01
NCGC00095978-02
SPECTRUM1505355
NCGC00095978-03
n-[[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]carbamoyl]-2,6-difluorobenzamide
lufenuron (usp/inn)
program [veterinary] (tn)
D08150
n-[[2,5-dichloro-4-(1,1,3,4,4,4-hexafluorobutyl)phenyl]carbamoyl]-2,6-difluoro-benzamide
A800670
NCGC00095978-04
HMS3264N09
C18434
tox21_111542
dtxsid5034357 ,
dtxcid3014357
cas-103055-07-8
tox21_300907
NCGC00254811-01
nsc-759097
nsc759097
pharmakon1600-01505355
smr001563631
MLS004712069
unii-1r754m4918
cga 184699
lufenuronum [inn-latin]
match (pesticide)
lufenurone [inn-french]
lufenuronum
lufenuron [inn:ban]
nsc 759097
n-(2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)-phenyl-aminocarbonyl)-2,6-difluorobenzamide
cigna
lufenurone
ec 410-690-9
1r754m4918 ,
program flavor tabs
FT-0631021
CHEMBL1364906
cga-184699
lufenuron (anhydrous) for veterinary use [ep impurity]
n-(((2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl)amino)carbonyl)-2,6-difluorobenzamide
(rs)-1-(2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl)-3-(2,6-difluorobenzoyl)urea
lufenuron [mart.]
lufenuron [mi]
sentinel component lufenuron
lufenuron [usp monograph]
program
lufenuron (anhydrous) for veterinary use
1-(2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl)-3-(2,6-difluorobenzoyl)-urea
lufenuron [green book]
lufenuron [usp-rs]
lufenuron [inn]
lufenuron component of sentinel
CCG-213976
AKOS022185021
SCHEMBL27105
NCGC00095978-06
tox21_111542_1
n-((2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl)carbamoyl)-2,6-difluorobenzamide
benzamide, n-[[[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]amino]carbonyl]-2,6-difluoro-
AB01563233_01
lufenuron;(rs)-1-[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy) phenyl]-3-(2,6-difluorobenzoyl) urea
9CR45YMS74 ,
n-[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)-phenyl-aminocarbonyl]-2,6-difluorobenzamide
J-521659
SR-01000872762-1
sr-01000872762
lufenuron, united states pharmacopeia (usp) reference standard
lufenuron, pestanal(r), analytical standard
lufenuron, (+)-
benzamide, n-(((2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl)amino)carbonyl)-2,6-difluoro-, (-)-
(+)-n-(((2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl)amino)carbonyl)-2,6-difluorobenzamide
(-)-n-(((2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl)amino)carbonyl)-2,6-difluorobenzamide
130841-26-8
130841-22-4
4629851K7Q ,
lufenuron, (-)-
benzamide, n-(((2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl)amino)carbonyl)-2,6-difluoro-, (+)-
lufenuron for peak identification, european pharmacopoeia (ep) reference standard
lufenuron, european pharmacopoeia (ep) reference standard
lufenuron anhydrous; 1-[2,5-dichloro-4-[(2rs)-1,1,2,3,3,3-hexafluoropropoxy]phenyl]-3-(2,6-difluorobenzoyl)urea
SBI-0207025.P001
unii-4629851k7q
unii-9cr45yms74
3-[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]-1-[(2,6-difluorophenyl)carbonyl]urea
n-(2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenylcarbamoyl)-2,6-difluorobenzamide
BCP15961
Q412933
DB11424
mfcd00867616
lufenuron 100 microg/ml in acetonitrile
AS-13363
BRD-A71774530-001-02-6
E78989
benzamide,n-[[[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]amino]carbonyl]-2,6-difluoro-
HY-115584
CS-0088780
L0358
(+)-n-((2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl)carbamoyl)-2,6-difluorobenzamide
lufenuron (anhydrous) for veterinary use (ep impurity)
lufenuronum (inn-latin)
lufenurone (inn-french)
lufenuron (usp-rs)
lufenuron (mart.)
program 6 month injectable for cats
program 6 month for cats
lufenuron (usp monograph)
program cat flavor tabs
program suspension
program (veterinary)

Excerpt	Reference	Relevance
" Although lufenuron is widely used in agriculture and aquaculture, rare are studies described that relates to possible toxic effects in fish."	( Acute and chronic toxicity of the benzoylurea pesticide, lufenuron, in the fish, Colossoma macropomum. Bezerra de Carvalho Júnior, L; Bezerra de Sá, F; Caroline Barros Lucas da Silva, S; Freitas da Silva, J; Gonçalves Cadena, P; Hugo Lima da Silva Souza, E; Lucas Corrêa de Andrade, A; Magliano da Cunha, F; Pinheiro Santos, T; Rafaela Leão Soares, P; Rodrigues Dos Santos, A; Sales Cadena, MR; Wanderley Teixeira, V, 2016)	0.43
" The evaluation of the chorion of the eggshell in this study has clarified the toxic effect of methomyl and cartap hydrochloride on eggs."	( Insecticide toxicity to the borer Neoleucinodes elegantalis (Guenée) (Lepidoptera: Crambidae): developmental and egg-laying effects. Arcanjo, LP; Costa, ÁH; Ferreira, DO; Martins, JC; Picanço, MC; Serrão, JE; Silva, RS; Soares, JRS, 2018)	0.48
" Since to our knowledge this study is the first in the open literature that evaluates the tiered approach in the sediment effect assessment procedure for pesticides, we advocate that similar evaluations should be conducted for pesticides that differ in toxic mode-of-action."	( Toxicity of sediment-bound lufenuron to benthic arthropods in laboratory bioassays. Belgers, JDM; Boerwinkel, MC; Brock, TCM; Jollie, L; Kraak, MHS; Papo, MJ; Roessink, I; Vonk, JA, 2018)	0.48

Excerpt	Reference	Relevance
"The efficacy of oral lufenuron, a chitin synthetase inhibitor, combined with topical enilconazole, was evaluated for the management of Microsporum canis infection in 100 cats housed in two catteries in France."	( Evaluation of the efficacy of oral lufenuron combined with topical enilconazole for the management of dermatophytosis in catteries. Chermette, R; Fournier, C; Guillot, J; Jankowski, F; Malandain, E; Rojzner, K; Schenker, R; Seewald, W; Touati, F, 2002)	0.31
"To evaluate and compare the in vitro antifungal properties of lufenuron and nikkomycin Z against isolates of Coccidioides immitis and Aspergillus fumigatus when used singly and in combination with the azole antifungal agent itraconazole."	( Comparison of susceptibility of fungal isolates to lufenuron and nikkomycin Z alone or in combination with itraconazole. Davidson, AP; Hector, RF; Johnson, SM, 2005)	0.33

Excerpt	Reference	Relevance
"In a bioavailability study in dogs we investigated the quantity of [14C]-Lufenuron and its metabolites in the skin by radioluminography."	( Determination of Lufenuron in canine skin layers by radioluminography. Hassler, S; Hotz, RP; Maurer, MP, 2000)	0.31
"The aim of this study was to offer data about the bioavailability of flufenoxuron, lufenuron, pyriproxyfen and fenoxycarb in common commodities like mandarin, apricot and peach."	( Bioavailability of insect growth regulators in citrus and stone fruits. Barba, A; Camara, MA; Mulero, J; Oliva, J; Paya, P; Zafrilla, P, 2007)	0.34
" The bioavailability of wines obtained from grapes in each assay and in standard solutions is also studied in order to establish matrix-related differences."	( Influence of the matrix in bioavailability of flufenoxuron, lufenuron, pyriproxyfen and fenoxycarb residues in grapes and wine. Barba, A; Cámara, MA; Mulero, J; Oliva, J; Payá, P, 2013)	0.39
"The ATP-binding cassette transporter P-glycoprotein (P-gp) is known to limit both brain penetration and oral bioavailability of many chemotherapy drugs."	( A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Ambudkar, SV; Brimacombe, KR; Chen, L; Gottesman, MM; Guha, R; Hall, MD; Klumpp-Thomas, C; Lee, OW; Lee, TD; Lusvarghi, S; Robey, RW; Shen, M; Tebase, BG, 2019)	0.51

Excerpt	Relevance	Reference
" Dogs of subgroups A, C, E, and G were treated with lufenuron monthly at a minimal target dosage of 10 mg/kg of body weight; those of subgroups B, D, F, and H were treated with excipient tablets."	( Efficacy of lufenuron against developmental stages of fleas (Ctenocephalides felis felis) in dogs housed in simulated home environments. Barnett, SH; Blagburn, BL; Hendrix, CM; Lindsay, DS; Vaughan, JL, 1995)	0.29
" Cats in each of 3 groups were treated orally with a 7% suspension formulation of lufenuron at dosage of 15, 30, or 45 mg/kg of body weight."	( Efficacy dosage titration of lufenuron against developmental stages of fleas (Ctenocephalides felis felis) in cats. Blagburn, BL; Lindsay, DS; Tebbitt, GL; Vaughan, JL, 1994)	0.29
" In cats, adult flea emergence was intensively prevented for 30 days by dosing of 15 mg/kg of lufenuron and 40 days by 30 or 60 mg/kg."	( Disinfestation of experimentally infested cat fleas, Ctenocephalides felis, on cats and dogs by oral lufenuron. Haga, C; Hayama, T; Nishida, Y; Oda, K, 1995)	0.29
" We conclude that oral lufenuron at the dosing schedule and conditions used in this study did not prevent dermatophytosis or alter the course of infection by direct topical challenge."	( Efficacy of pre-treatment with lufenuron for the prevention of Microsporum canis infection in a feline direct topical challenge model. Blum, JL; Deboer, DJ; Moriello, KA; Schenker, R; Volk, LM, 2004)	0.32

Class	Description
benzoylurea insecticide
dichlorobenzene	Any member of the class of chlorobenzenes carrying two chloro groups at unspecified positions.
N-acylurea	A member of the class of ureas that has the general formula R-CO-NH-CO-NH2 or R-CO-NH-CO-NH-CO-R', formally derived by the acylation of one or both of the nitrogens of a urea moiety.
aromatic ether	Any ether in which the oxygen is attached to at least one aryl substituent.
organofluorine compound	An organofluorine compound is a compound containing at least one carbon-fluorine bond.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Protein	Taxonomy	Measurement	Average (µ)	Min (ref.)	Avg (ref.)	Max (ref.)	Bioassay(s)
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	Homo sapiens (human)	Potency	50.1187	0.0032	45.4673	12,589.2998	AID2517
15-lipoxygenase, partial	Homo sapiens (human)	Potency	15.8489	0.0126	10.6917	88.5700	AID887
hypoxia-inducible factor 1 alpha subunit	Homo sapiens (human)	Potency	21.8724	3.1890	29.8841	59.4836	AID1224846
USP1 protein, partial	Homo sapiens (human)	Potency	11.2202	0.0316	37.5844	354.8130	AID504865
TDP1 protein	Homo sapiens (human)	Potency	1.4593	0.0008	11.3822	44.6684	AID686978; AID686979
GLI family zinc finger 3	Homo sapiens (human)	Potency	3.7307	0.0007	14.5928	83.7951	AID1259392
Microtubule-associated protein tau	Homo sapiens (human)	Potency	11.8230	0.1800	13.5574	39.8107	AID1460; AID1468
AR protein	Homo sapiens (human)	Potency	22.2119	0.0002	21.2231	8,912.5098	AID1259243; AID1259247; AID743042; AID743054
cytochrome P450 family 3 subfamily A polypeptide 4	Homo sapiens (human)	Potency	3.8902	0.0123	7.9835	43.2770	AID1645841
retinoic acid nuclear receptor alpha variant 1	Homo sapiens (human)	Potency	18.4908	0.0030	41.6115	22,387.1992	AID1159552; AID1159555
retinoid X nuclear receptor alpha	Homo sapiens (human)	Potency	4.9167	0.0008	17.5051	59.3239	AID1159527; AID1159531
estrogen-related nuclear receptor alpha	Homo sapiens (human)	Potency	8.1821	0.0015	30.6073	15,848.9004	AID1224848; AID1224849; AID1259403
pregnane X nuclear receptor	Homo sapiens (human)	Potency	33.2070	0.0054	28.0263	1,258.9301	AID1346982; AID720659
estrogen nuclear receptor alpha	Homo sapiens (human)	Potency	17.1852	0.0002	29.3054	16,493.5996	AID1259244; AID1259248; AID743075; AID743078; AID743079; AID743091
G	Vesicular stomatitis virus	Potency	19.4971	0.0123	8.9648	39.8107	AID1645842
vitamin D (1,25- dihydroxyvitamin D3) receptor	Homo sapiens (human)	Potency	48.9662	0.0237	23.2282	63.5986	AID743223
thyroid stimulating hormone receptor	Homo sapiens (human)	Potency	26.6032	0.0016	28.0151	77.1139	AID1259385
v-jun sarcoma virus 17 oncogene homolog (avian)	Homo sapiens (human)	Potency	19.3050	0.0578	21.1097	61.2679	AID1159526; AID1159528
ubiquitin carboxyl-terminal hydrolase 2 isoform a	Homo sapiens (human)	Potency	12.5893	0.6561	9.4520	25.1189	AID927
nuclear factor erythroid 2-related factor 2 isoform 1	Homo sapiens (human)	Potency	26.4100	0.0006	27.2152	1,122.0200	AID651741; AID743219
nuclear receptor ROR-gamma isoform 1	Mus musculus (house mouse)	Potency	15.1861	0.0079	8.2332	1,122.0200	AID2546; AID2551
peripheral myelin protein 22	Rattus norvegicus (Norway rat)	Potency	24.9831	0.0056	12.3677	36.1254	AID624032; AID624044
Voltage-dependent calcium channel gamma-2 subunit	Mus musculus (house mouse)	Potency	33.4915	0.0015	57.7890	15,848.9004	AID1259244
Interferon beta	Homo sapiens (human)	Potency	19.4971	0.0033	9.1582	39.8107	AID1645842
HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)	Potency	19.4971	0.0123	8.9648	39.8107	AID1645842
Glutamate receptor 2	Rattus norvegicus (Norway rat)	Potency	33.4915	0.0015	51.7393	15,848.9004	AID1259244
Spike glycoprotein	Severe acute respiratory syndrome-related coronavirus	Potency	39.8107	0.0096	10.5250	35.4813	AID1479145
Disintegrin and metalloproteinase domain-containing protein 17	Homo sapiens (human)	Potency	12.5893	1.5849	13.0043	25.1189	AID927
Inositol hexakisphosphate kinase 1	Homo sapiens (human)	Potency	19.4971	0.0123	8.9648	39.8107	AID1645842
cytochrome P450 2C9, partial	Homo sapiens (human)	Potency	19.4971	0.0123	8.9648	39.8107	AID1645842
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Process	via Protein(s)	Taxonomy
cell surface receptor signaling pathway via JAK-STAT	Interferon beta	Homo sapiens (human)
response to exogenous dsRNA	Interferon beta	Homo sapiens (human)
B cell activation involved in immune response	Interferon beta	Homo sapiens (human)
cell surface receptor signaling pathway	Interferon beta	Homo sapiens (human)
cell surface receptor signaling pathway via JAK-STAT	Interferon beta	Homo sapiens (human)
response to virus	Interferon beta	Homo sapiens (human)
positive regulation of autophagy	Interferon beta	Homo sapiens (human)
cytokine-mediated signaling pathway	Interferon beta	Homo sapiens (human)
natural killer cell activation	Interferon beta	Homo sapiens (human)
positive regulation of peptidyl-serine phosphorylation of STAT protein	Interferon beta	Homo sapiens (human)
cellular response to interferon-beta	Interferon beta	Homo sapiens (human)
B cell proliferation	Interferon beta	Homo sapiens (human)
negative regulation of viral genome replication	Interferon beta	Homo sapiens (human)
innate immune response	Interferon beta	Homo sapiens (human)
positive regulation of innate immune response	Interferon beta	Homo sapiens (human)
regulation of MHC class I biosynthetic process	Interferon beta	Homo sapiens (human)
negative regulation of T cell differentiation	Interferon beta	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	Interferon beta	Homo sapiens (human)
defense response to virus	Interferon beta	Homo sapiens (human)
type I interferon-mediated signaling pathway	Interferon beta	Homo sapiens (human)
neuron cellular homeostasis	Interferon beta	Homo sapiens (human)
cellular response to exogenous dsRNA	Interferon beta	Homo sapiens (human)
cellular response to virus	Interferon beta	Homo sapiens (human)
negative regulation of Lewy body formation	Interferon beta	Homo sapiens (human)
negative regulation of T-helper 2 cell cytokine production	Interferon beta	Homo sapiens (human)
positive regulation of apoptotic signaling pathway	Interferon beta	Homo sapiens (human)
response to exogenous dsRNA	Interferon beta	Homo sapiens (human)
B cell differentiation	Interferon beta	Homo sapiens (human)
natural killer cell activation involved in immune response	Interferon beta	Homo sapiens (human)
adaptive immune response	Interferon beta	Homo sapiens (human)
T cell activation involved in immune response	Interferon beta	Homo sapiens (human)
humoral immune response	Interferon beta	Homo sapiens (human)
positive regulation of T cell mediated cytotoxicity	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
adaptive immune response	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
regulation of T cell anergy	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
defense response	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
immune response	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
detection of bacterium	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
regulation of interleukin-12 production	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
regulation of interleukin-6 production	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
protection from natural killer cell mediated cytotoxicity	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
innate immune response	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
regulation of dendritic cell differentiation	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
antigen processing and presentation of endogenous peptide antigen via MHC class Ib	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
positive regulation of epidermal growth factor receptor signaling pathway	Disintegrin and metalloproteinase domain-containing protein 17	Homo sapiens (human)
response to hypoxia	Disintegrin and metalloproteinase domain-containing protein 17	Homo sapiens (human)
neutrophil mediated immunity	Disintegrin and metalloproteinase domain-containing protein 17	Homo sapiens (human)
germinal center formation	Disintegrin and metalloproteinase domain-containing protein 17	Homo sapiens (human)
positive regulation of leukocyte chemotaxis	Disintegrin and metalloproteinase domain-containing protein 17	Homo sapiens (human)
proteolysis	Disintegrin and metalloproteinase domain-containing protein 17	Homo sapiens (human)
membrane protein ectodomain proteolysis	Disintegrin and metalloproteinase domain-containing protein 17	Homo sapiens (human)
cell adhesion	Disintegrin and metalloproteinase domain-containing protein 17	Homo sapiens (human)
Notch receptor processing	Disintegrin and metalloproteinase domain-containing protein 17	Homo sapiens (human)
positive regulation of cell population proliferation	Disintegrin and metalloproteinase domain-containing protein 17	Homo sapiens (human)
response to xenobiotic stimulus	Disintegrin and metalloproteinase domain-containing protein 17	Homo sapiens (human)
positive regulation of T cell chemotaxis	Disintegrin and metalloproteinase domain-containing protein 17	Homo sapiens (human)
protein processing	Disintegrin and metalloproteinase domain-containing protein 17	Homo sapiens (human)
signal release	Disintegrin and metalloproteinase domain-containing protein 17	Homo sapiens (human)
B cell differentiation	Disintegrin and metalloproteinase domain-containing protein 17	Homo sapiens (human)
positive regulation of cell growth	Disintegrin and metalloproteinase domain-containing protein 17	Homo sapiens (human)
positive regulation of cell migration	Disintegrin and metalloproteinase domain-containing protein 17	Homo sapiens (human)
negative regulation of transforming growth factor beta receptor signaling pathway	Disintegrin and metalloproteinase domain-containing protein 17	Homo sapiens (human)
response to lipopolysaccharide	Disintegrin and metalloproteinase domain-containing protein 17	Homo sapiens (human)
positive regulation of chemokine production	Disintegrin and metalloproteinase domain-containing protein 17	Homo sapiens (human)
positive regulation of tumor necrosis factor production	Disintegrin and metalloproteinase domain-containing protein 17	Homo sapiens (human)
regulation of mast cell apoptotic process	Disintegrin and metalloproteinase domain-containing protein 17	Homo sapiens (human)
T cell differentiation in thymus	Disintegrin and metalloproteinase domain-containing protein 17	Homo sapiens (human)
cell adhesion mediated by integrin	Disintegrin and metalloproteinase domain-containing protein 17	Homo sapiens (human)
wound healing, spreading of epidermal cells	Disintegrin and metalloproteinase domain-containing protein 17	Homo sapiens (human)
amyloid precursor protein catabolic process	Disintegrin and metalloproteinase domain-containing protein 17	Homo sapiens (human)
positive regulation of blood vessel endothelial cell migration	Disintegrin and metalloproteinase domain-containing protein 17	Homo sapiens (human)
positive regulation of cyclin-dependent protein serine/threonine kinase activity	Disintegrin and metalloproteinase domain-containing protein 17	Homo sapiens (human)
positive regulation of epidermal growth factor-activated receptor activity	Disintegrin and metalloproteinase domain-containing protein 17	Homo sapiens (human)
positive regulation of epidermal growth factor receptor signaling pathway	Disintegrin and metalloproteinase domain-containing protein 17	Homo sapiens (human)
spleen development	Disintegrin and metalloproteinase domain-containing protein 17	Homo sapiens (human)
cell motility	Disintegrin and metalloproteinase domain-containing protein 17	Homo sapiens (human)
defense response to Gram-positive bacterium	Disintegrin and metalloproteinase domain-containing protein 17	Homo sapiens (human)
cellular response to high density lipoprotein particle stimulus	Disintegrin and metalloproteinase domain-containing protein 17	Homo sapiens (human)
commissural neuron axon guidance	Disintegrin and metalloproteinase domain-containing protein 17	Homo sapiens (human)
negative regulation of cold-induced thermogenesis	Disintegrin and metalloproteinase domain-containing protein 17	Homo sapiens (human)
positive regulation of G1/S transition of mitotic cell cycle	Disintegrin and metalloproteinase domain-containing protein 17	Homo sapiens (human)
positive regulation of tumor necrosis factor-mediated signaling pathway	Disintegrin and metalloproteinase domain-containing protein 17	Homo sapiens (human)
positive regulation of vascular endothelial cell proliferation	Disintegrin and metalloproteinase domain-containing protein 17	Homo sapiens (human)
Notch signaling pathway	Disintegrin and metalloproteinase domain-containing protein 17	Homo sapiens (human)
inositol phosphate metabolic process	Inositol hexakisphosphate kinase 1	Homo sapiens (human)
phosphatidylinositol phosphate biosynthetic process	Inositol hexakisphosphate kinase 1	Homo sapiens (human)
negative regulation of cold-induced thermogenesis	Inositol hexakisphosphate kinase 1	Homo sapiens (human)
inositol phosphate biosynthetic process	Inositol hexakisphosphate kinase 1	Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Process	via Protein(s)	Taxonomy
cytokine activity	Interferon beta	Homo sapiens (human)
cytokine receptor binding	Interferon beta	Homo sapiens (human)
type I interferon receptor binding	Interferon beta	Homo sapiens (human)
protein binding	Interferon beta	Homo sapiens (human)
chloramphenicol O-acetyltransferase activity	Interferon beta	Homo sapiens (human)
TAP binding	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
signaling receptor binding	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
protein binding	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
peptide antigen binding	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
TAP binding	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
protein-folding chaperone binding	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
endopeptidase activity	Disintegrin and metalloproteinase domain-containing protein 17	Homo sapiens (human)
metalloendopeptidase activity	Disintegrin and metalloproteinase domain-containing protein 17	Homo sapiens (human)
Notch binding	Disintegrin and metalloproteinase domain-containing protein 17	Homo sapiens (human)
interleukin-6 receptor binding	Disintegrin and metalloproteinase domain-containing protein 17	Homo sapiens (human)
integrin binding	Disintegrin and metalloproteinase domain-containing protein 17	Homo sapiens (human)
protein binding	Disintegrin and metalloproteinase domain-containing protein 17	Homo sapiens (human)
peptidase activity	Disintegrin and metalloproteinase domain-containing protein 17	Homo sapiens (human)
metallopeptidase activity	Disintegrin and metalloproteinase domain-containing protein 17	Homo sapiens (human)
SH3 domain binding	Disintegrin and metalloproteinase domain-containing protein 17	Homo sapiens (human)
cytokine binding	Disintegrin and metalloproteinase domain-containing protein 17	Homo sapiens (human)
PDZ domain binding	Disintegrin and metalloproteinase domain-containing protein 17	Homo sapiens (human)
tumor necrosis factor binding	Disintegrin and metalloproteinase domain-containing protein 17	Homo sapiens (human)
metal ion binding	Disintegrin and metalloproteinase domain-containing protein 17	Homo sapiens (human)
metalloendopeptidase activity involved in amyloid precursor protein catabolic process	Disintegrin and metalloproteinase domain-containing protein 17	Homo sapiens (human)
inositol-1,3,4,5,6-pentakisphosphate kinase activity	Inositol hexakisphosphate kinase 1	Homo sapiens (human)
inositol hexakisphosphate kinase activity	Inositol hexakisphosphate kinase 1	Homo sapiens (human)
inositol heptakisphosphate kinase activity	Inositol hexakisphosphate kinase 1	Homo sapiens (human)
inositol hexakisphosphate 5-kinase activity	Inositol hexakisphosphate kinase 1	Homo sapiens (human)
protein binding	Inositol hexakisphosphate kinase 1	Homo sapiens (human)
ATP binding	Inositol hexakisphosphate kinase 1	Homo sapiens (human)
inositol hexakisphosphate 1-kinase activity	Inositol hexakisphosphate kinase 1	Homo sapiens (human)
inositol hexakisphosphate 3-kinase activity	Inositol hexakisphosphate kinase 1	Homo sapiens (human)
inositol 5-diphosphate pentakisphosphate 5-kinase activity	Inositol hexakisphosphate kinase 1	Homo sapiens (human)
inositol diphosphate tetrakisphosphate kinase activity	Inositol hexakisphosphate kinase 1	Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Process	via Protein(s)	Taxonomy
extracellular space	Interferon beta	Homo sapiens (human)
extracellular region	Interferon beta	Homo sapiens (human)
Golgi membrane	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
endoplasmic reticulum	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
Golgi apparatus	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
plasma membrane	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
cell surface	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
ER to Golgi transport vesicle membrane	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
membrane	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
secretory granule membrane	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
phagocytic vesicle membrane	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
early endosome membrane	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
recycling endosome membrane	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
extracellular exosome	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
lumenal side of endoplasmic reticulum membrane	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
MHC class I protein complex	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
extracellular space	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
external side of plasma membrane	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
plasma membrane	Glutamate receptor 2	Rattus norvegicus (Norway rat)
virion membrane	Spike glycoprotein	Severe acute respiratory syndrome-related coronavirus
cell-cell junction	Disintegrin and metalloproteinase domain-containing protein 17	Homo sapiens (human)
focal adhesion	Disintegrin and metalloproteinase domain-containing protein 17	Homo sapiens (human)
ruffle membrane	Disintegrin and metalloproteinase domain-containing protein 17	Homo sapiens (human)
Golgi membrane	Disintegrin and metalloproteinase domain-containing protein 17	Homo sapiens (human)
cytoplasm	Disintegrin and metalloproteinase domain-containing protein 17	Homo sapiens (human)
endoplasmic reticulum lumen	Disintegrin and metalloproteinase domain-containing protein 17	Homo sapiens (human)
cytosol	Disintegrin and metalloproteinase domain-containing protein 17	Homo sapiens (human)
plasma membrane	Disintegrin and metalloproteinase domain-containing protein 17	Homo sapiens (human)
cell surface	Disintegrin and metalloproteinase domain-containing protein 17	Homo sapiens (human)
actin cytoskeleton	Disintegrin and metalloproteinase domain-containing protein 17	Homo sapiens (human)
membrane	Disintegrin and metalloproteinase domain-containing protein 17	Homo sapiens (human)
apical plasma membrane	Disintegrin and metalloproteinase domain-containing protein 17	Homo sapiens (human)
membrane raft	Disintegrin and metalloproteinase domain-containing protein 17	Homo sapiens (human)
plasma membrane	Disintegrin and metalloproteinase domain-containing protein 17	Homo sapiens (human)
fibrillar center	Inositol hexakisphosphate kinase 1	Homo sapiens (human)
nucleoplasm	Inositol hexakisphosphate kinase 1	Homo sapiens (human)
cytosol	Inositol hexakisphosphate kinase 1	Homo sapiens (human)
nucleus	Inositol hexakisphosphate kinase 1	Homo sapiens (human)
cytoplasm	Inositol hexakisphosphate kinase 1	Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Bioassays (215)

Assay ID	Title	Year	Journal	Article
AID1111459	Reduction of fertility in 7 days old adult of Anastrepha striata assessed as reduction of egg hatching at 0.1 mg/g treated with diet measured after 5 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111430	Reduction of fertility in 7 days old adult of Anastrepha striata assessed as reduction of egg hatching at 30 mg/g treated with diet measured after 3 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111420	Effect on fecundity in 7 days old adult male of Anastrepha obliqua at 30 mg/g treated with diet after 24 hr in presence of untreated adult female of Anastrepha obliqua	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111514	Reduction of fertility in 7 days old adult of Anastrepha obliqua assessed as reduction of egg hatching at 5 mg/g treated with diet measured after 3 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111434	Reduction of fertility in 7 days old adult of Anastrepha striata assessed as reduction of egg hatching at 10 mg/g treated with diet measured after 5 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111518	Reduction of fertility in 7 days old adult of Anastrepha obliqua assessed as reduction of egg hatching at 1 mg/g treated with diet measured after 7 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111487	Reduction of fertility in 7 days old adult of Anastrepha serpentina assessed as reduction of egg hatching at 0.5 mg/g treated with diet measured after 9 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111534	Reduction of fertility in 7 days old adult of Anastrepha ludens assessed as reduction of egg hatching at 30 mg/g treated with diet measured after 11 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111437	Reduction of fertility in 7 days old adult of Anastrepha striata assessed as reduction of egg hatching at 10 mg/g treated with diet measured after 1 day oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111490	Reduction of fertility in 7 days old adult of Anastrepha serpentina assessed as reduction of egg hatching at 0.5 mg/g treated with diet measured after 3 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111499	Reduction of fertility in 7 days old adult of Anastrepha obliqua assessed as reduction of egg hatching at 30 mg/g treated with diet measured after 9 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111447	Reduction of fertility in 7 days old adult of Anastrepha striata assessed as reduction of egg hatching at 1 mg/g treated with diet measured after 5 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111537	Reduction of fertility in 7 days old adult of Anastrepha ludens assessed as reduction of egg hatching at 30 mg/g treated with diet measured after 5 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111442	Reduction of fertility in 7 days old adult of Anastrepha striata assessed as reduction of egg hatching at 5 mg/g treated with diet measured after 3 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111568	Reduction of fertility in 7 days old adult of Anastrepha ludens assessed as reduction of egg hatching at 0.1 mg/g treated with diet measured after 3 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111452	Reduction of fertility in 7 days old adult of Anastrepha striata assessed as reduction of egg hatching at 0.5 mg/g treated with diet measured after 7 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID677615	Antifungal activity against Cryptococcus neoformans NCIM 3542 after 48 hrs by microbroth dilution method	2012	Bioorganic & medicinal chemistry letters, Sep-01, Volume: 22, Issue:17	Hybrid molecules of carvacrol and benzoyl urea/thiourea with potential applications in agriculture and medicine.
AID1111526	Reduction of fertility in 7 days old adult of Anastrepha obliqua assessed as reduction of egg hatching at 0.5 mg/g treated with diet measured after 3 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111478	Reduction of fertility in 7 days old adult of Anastrepha serpentina assessed as reduction of egg hatching at 5 mg/g treated with diet measured after 3 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111566	Reduction of fertility in 7 days old adult of Anastrepha ludens assessed as reduction of egg hatching at 0.1 mg/g treated with diet measured after 7 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111564	Reduction of fertility in 7 days old adult of Anastrepha ludens assessed as reduction of egg hatching at 0.1 mg/g treated with diet measured after 11 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111550	Reduction of fertility in 7 days old adult of Anastrepha ludens assessed as reduction of egg hatching at 5 mg/g treated with diet measured after 3 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111553	Reduction of fertility in 7 days old adult of Anastrepha ludens assessed as reduction of egg hatching at 1 mg/g treated with diet measured after 9 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111462	Reduction of fertility in 7 days old adult of Anastrepha serpentina assessed as reduction of egg hatching at 30 mg/g treated with diet measured after 11 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111560	Reduction of fertility in 7 days old adult of Anastrepha ludens assessed as reduction of egg hatching at 0.5 mg/g treated with diet measured after 7 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID677536	Antifungal activity against Dreschlera oryzae after 48 hrs by microbroth dilution method	2012	Bioorganic & medicinal chemistry letters, Sep-01, Volume: 22, Issue:17	Hybrid molecules of carvacrol and benzoyl urea/thiourea with potential applications in agriculture and medicine.
AID677616	Antifungal activity against Cryptococcus neoformans NCIM 3378 after 48 hrs by microbroth dilution method	2012	Bioorganic & medicinal chemistry letters, Sep-01, Volume: 22, Issue:17	Hybrid molecules of carvacrol and benzoyl urea/thiourea with potential applications in agriculture and medicine.
AID1111440	Reduction of fertility in 7 days old adult of Anastrepha striata assessed as reduction of egg hatching at 5 mg/g treated with diet measured after 7 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111520	Reduction of fertility in 7 days old adult of Anastrepha obliqua assessed as reduction of egg hatching at 1 mg/g treated with diet measured after 3 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111562	Reduction of fertility in 7 days old adult of Anastrepha ludens assessed as reduction of egg hatching at 0.5 mg/g treated with diet measured after 3 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111554	Reduction of fertility in 7 days old adult of Anastrepha ludens assessed as reduction of egg hatching at 1 mg/g treated with diet measured after 7 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111540	Reduction of fertility in 7 days old adult of Anastrepha ludens assessed as reduction of egg hatching at 10 mg/g treated with diet measured after 11 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111556	Reduction of fertility in 7 days old adult of Anastrepha ludens assessed as reduction of egg hatching at 1 mg/g treated with diet measured after 3 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111433	Reduction of fertility in 7 days old adult of Anastrepha striata assessed as reduction of egg hatching at 10 mg/g treated with diet measured after 9 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111532	Reduction of fertility in 7 days old adult of Anastrepha obliqua assessed as reduction of egg hatching at 0.1 mg/g treated with diet measured after 3 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111486	Reduction of fertility in 7 days old adult of Anastrepha serpentina assessed as reduction of egg hatching at 0.5 mg/g treated with diet measured after 11 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111448	Reduction of fertility in 7 days old adult of Anastrepha striata assessed as reduction of egg hatching at 1 mg/g treated with diet measured after 1 day oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111548	Reduction of fertility in 7 days old adult of Anastrepha ludens assessed as reduction of egg hatching at 5 mg/g treated with diet measured after 7 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111417	Effect on fertility in 7 days old adult female of Anastrepha ludens at 30 mg/g treated with diet after 24 hr in presence of untreated adult male of Anastrepha ludens	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111471	Reduction of fertility in 7 days old adult of Anastrepha serpentina assessed as reduction of egg hatching at 10 mg/g treated with diet measured after 5 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111429	Reduction of fertility in 7 days old adult of Anastrepha striata assessed as reduction of egg hatching at 30 mg/g treated with diet measured after 5 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111549	Reduction of fertility in 7 days old adult of Anastrepha ludens assessed as reduction of egg hatching at 5 mg/g treated with diet measured after 5 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111569	Reduction of fertility in 7 days old adult of Anastrepha ludens assessed as reduction of egg hatching at 0.1 mg/g treated with diet measured after 1 day oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111438	Reduction of fertility in 7 days old adult of Anastrepha striata assessed as reduction of egg hatching at 5 mg/g treated with diet measured after 11 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111431	Reduction of fertility in 7 days old adult of Anastrepha striata assessed as reduction of egg hatching at 30 mg/g treated with diet measured after 1 day oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111527	Reduction of fertility in 7 days old adult of Anastrepha obliqua assessed as reduction of egg hatching at 0.5 mg/g treated with diet measured after 1 day oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111559	Reduction of fertility in 7 days old adult of Anastrepha ludens assessed as reduction of egg hatching at 0.5 mg/g treated with diet measured after 9 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111450	Reduction of fertility in 7 days old adult of Anastrepha striata assessed as reduction of egg hatching at 0.5 mg/g treated with diet measured after 11 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111472	Reduction of fertility in 7 days old adult of Anastrepha serpentina assessed as reduction of egg hatching at 10 mg/g treated with diet measured after 3 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111544	Reduction of fertility in 7 days old adult of Anastrepha ludens assessed as reduction of egg hatching at 10 mg/g treated with diet measured after 3 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111511	Reduction of fertility in 7 days old adult of Anastrepha obliqua assessed as reduction of egg hatching at 5 mg/g treated with diet measured after 9 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111476	Reduction of fertility in 7 days old adult of Anastrepha serpentina assessed as reduction of egg hatching at 5 mg/g treated with diet measured after 7 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID677538	Antifungal activity against Pichia membranifaciens after 48 hrs by microbroth dilution method	2012	Bioorganic & medicinal chemistry letters, Sep-01, Volume: 22, Issue:17	Hybrid molecules of carvacrol and benzoyl urea/thiourea with potential applications in agriculture and medicine.
AID1111445	Reduction of fertility in 7 days old adult of Anastrepha striata assessed as reduction of egg hatching at 1 mg/g treated with diet measured after 9 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111423	Effect on fecundity in 7 days old adult female of Anastrepha serpentina at 30 mg/g treated with diet after 24 hr in presence of untreated adult male of Anastrepha serpentina	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID677613	Antifungal activity against Cryptococcus neoformans after 48 hrs by microbroth dilution method	2012	Bioorganic & medicinal chemistry letters, Sep-01, Volume: 22, Issue:17	Hybrid molecules of carvacrol and benzoyl urea/thiourea with potential applications in agriculture and medicine.
AID1111522	Reduction of fertility in 7 days old adult of Anastrepha obliqua assessed as reduction of egg hatching at 0.5 mg/g treated with diet measured after 11 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111507	Reduction of fertility in 7 days old adult of Anastrepha obliqua assessed as reduction of egg hatching at 10 mg/g treated with diet measured after 5 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111491	Reduction of fertility in 7 days old adult of Anastrepha serpentina assessed as reduction of egg hatching at 0.5 mg/g treated with diet measured after 1 day oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111436	Reduction of fertility in 7 days old adult of Anastrepha striata assessed as reduction of egg hatching at 10 mg/g treated with diet measured after 3 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111508	Reduction of fertility in 7 days old adult of Anastrepha obliqua assessed as reduction of egg hatching at 10 mg/g treated with diet measured after 3 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111557	Reduction of fertility in 7 days old adult of Anastrepha ludens assessed as reduction of egg hatching at 1 mg/g treated with diet measured after 1 day oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111512	Reduction of fertility in 7 days old adult of Anastrepha obliqua assessed as reduction of egg hatching at 5 mg/g treated with diet measured after 7 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111561	Reduction of fertility in 7 days old adult of Anastrepha ludens assessed as reduction of egg hatching at 0.5 mg/g treated with diet measured after 5 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111467	Reduction of fertility in 7 days old adult of Anastrepha serpentina assessed as reduction of egg hatching at 30 mg/g treated with diet measured after 1 day oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111435	Reduction of fertility in 7 days old adult of Anastrepha striata assessed as reduction of egg hatching at 10 mg/g treated with diet measured after 7 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111455	Reduction of fertility in 7 days old adult of Anastrepha striata assessed as reduction of egg hatching at 0.5 mg/g treated with diet measured after 1 day oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111463	Reduction of fertility in 7 days old adult of Anastrepha serpentina assessed as reduction of egg hatching at 30 mg/g treated with diet measured after 9 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID677617	Toxicity in RBC assessed as induction of hemolysis	2012	Bioorganic & medicinal chemistry letters, Sep-01, Volume: 22, Issue:17	Hybrid molecules of carvacrol and benzoyl urea/thiourea with potential applications in agriculture and medicine.
AID1111519	Reduction of fertility in 7 days old adult of Anastrepha obliqua assessed as reduction of egg hatching at 1 mg/g treated with diet measured after 5 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111552	Reduction of fertility in 7 days old adult of Anastrepha ludens assessed as reduction of egg hatching at 1 mg/g treated with diet measured after 11 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111451	Reduction of fertility in 7 days old adult of Anastrepha striata assessed as reduction of egg hatching at 0.5 mg/g treated with diet measured after 9 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111565	Reduction of fertility in 7 days old adult of Anastrepha ludens assessed as reduction of egg hatching at 0.1 mg/g treated with diet measured after 9 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111555	Reduction of fertility in 7 days old adult of Anastrepha ludens assessed as reduction of egg hatching at 1 mg/g treated with diet measured after 5 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111479	Reduction of fertility in 7 days old adult of Anastrepha serpentina assessed as reduction of egg hatching at 5 mg/g treated with diet measured after 1 day oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111525	Reduction of fertility in 7 days old adult of Anastrepha obliqua assessed as reduction of egg hatching at 0.5 mg/g treated with diet measured after 5 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111444	Reduction of fertility in 7 days old adult of Anastrepha striata assessed as reduction of egg hatching at 1 mg/g treated with diet measured after 11 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID677610	Antifungal activity against Candida albicans after 48 hrs by microbroth dilution method	2012	Bioorganic & medicinal chemistry letters, Sep-01, Volume: 22, Issue:17	Hybrid molecules of carvacrol and benzoyl urea/thiourea with potential applications in agriculture and medicine.
AID1111441	Reduction of fertility in 7 days old adult of Anastrepha striata assessed as reduction of egg hatching at 5 mg/g treated with diet measured after 5 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111456	Reduction of fertility in 7 days old adult of Anastrepha striata assessed as reduction of egg hatching at 0.1 mg/g treated with diet measured after 11 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111446	Reduction of fertility in 7 days old adult of Anastrepha striata assessed as reduction of egg hatching at 1 mg/g treated with diet measured after 7 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111457	Reduction of fertility in 7 days old adult of Anastrepha striata assessed as reduction of egg hatching at 0.1 mg/g treated with diet measured after 9 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111523	Reduction of fertility in 7 days old adult of Anastrepha obliqua assessed as reduction of egg hatching at 0.5 mg/g treated with diet measured after 9 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111480	Reduction of fertility in 7 days old adult of Anastrepha serpentina assessed as reduction of egg hatching at 1 mg/g treated with diet measured after 11 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111421	Effect on fecundity in 7 days old adult male of Anastrepha ludens at 30 mg/g treated with diet after 24 hr in presence of untreated adult female of Anastrepha ludens	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111466	Reduction of fertility in 7 days old adult of Anastrepha serpentina assessed as reduction of egg hatching at 30 mg/g treated with diet measured after 3 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID677614	Antifungal activity against Cryptococcus neoformans NCIM 3541 after 48 hrs by microbroth dilution method	2012	Bioorganic & medicinal chemistry letters, Sep-01, Volume: 22, Issue:17	Hybrid molecules of carvacrol and benzoyl urea/thiourea with potential applications in agriculture and medicine.
AID1111492	Reduction of fertility in 7 days old adult of Anastrepha serpentina assessed as reduction of egg hatching at 0.1 mg/g treated with diet measured after 11 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111460	Reduction of fertility in 7 days old adult of Anastrepha striata assessed as reduction of egg hatching at 0.1 mg/g treated with diet measured after 3 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111414	Effect on fertility in 7 days old adult female of Anastrepha striata at 30 mg/g treated with diet after 24 hr in presence of untreated adult male of Anastrepha striata	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111541	Reduction of fertility in 7 days old adult of Anastrepha ludens assessed as reduction of egg hatching at 10 mg/g treated with diet measured after 9 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111505	Reduction of fertility in 7 days old adult of Anastrepha obliqua assessed as reduction of egg hatching at 10 mg/g treated with diet measured after 9 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111493	Reduction of fertility in 7 days old adult of Anastrepha serpentina assessed as reduction of egg hatching at 0.1 mg/g treated with diet measured after 9 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111570	Effect on fecundity in 7 days old adult of Anastrepha striata at 0.1 to 30 mg/g treated with diet after 24 hr	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111545	Reduction of fertility in 7 days old adult of Anastrepha ludens assessed as reduction of egg hatching at 10 mg/g treated with diet measured after 1 day oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111500	Reduction of fertility in 7 days old adult of Anastrepha obliqua assessed as reduction of egg hatching at 30 mg/g treated with diet measured after 7 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111551	Reduction of fertility in 7 days old adult of Anastrepha ludens assessed as reduction of egg hatching at 5 mg/g treated with diet measured after 1 day oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111461	Reduction of fertility in 7 days old adult of Anastrepha striata assessed as reduction of egg hatching at 0.1 mg/g treated with diet measured after 1 day oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111439	Reduction of fertility in 7 days old adult of Anastrepha striata assessed as reduction of egg hatching at 5 mg/g treated with diet measured after 9 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111484	Reduction of fertility in 7 days old adult of Anastrepha serpentina assessed as reduction of egg hatching at 1 mg/g treated with diet measured after 3 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID677534	Antifungal activity against Magnaporthe grisea after 48 hrs by microbroth dilution method	2012	Bioorganic & medicinal chemistry letters, Sep-01, Volume: 22, Issue:17	Hybrid molecules of carvacrol and benzoyl urea/thiourea with potential applications in agriculture and medicine.
AID1111411	Effect on fertility in 7 days old adult male of Anastrepha serpentina at 30 mg/g treated with diet after 24 hr in presence of untreated adult female of Anastrepha serpentina	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111465	Reduction of fertility in 7 days old adult of Anastrepha serpentina assessed as reduction of egg hatching at 30 mg/g treated with diet measured after 5 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111489	Reduction of fertility in 7 days old adult of Anastrepha serpentina assessed as reduction of egg hatching at 0.5 mg/g treated with diet measured after 5 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111443	Reduction of fertility in 7 days old adult of Anastrepha striata assessed as reduction of egg hatching at 5 mg/g treated with diet measured after 1 day oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID677537	Antifungal activity against Debaryomyces hansenii after 48 hrs by microbroth dilution method	2012	Bioorganic & medicinal chemistry letters, Sep-01, Volume: 22, Issue:17	Hybrid molecules of carvacrol and benzoyl urea/thiourea with potential applications in agriculture and medicine.
AID1111482	Reduction of fertility in 7 days old adult of Anastrepha serpentina assessed as reduction of egg hatching at 1 mg/g treated with diet measured after 7 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID677535	Antifungal activity against Fusarium oxysporum after 48 hrs by microbroth dilution method	2012	Bioorganic & medicinal chemistry letters, Sep-01, Volume: 22, Issue:17	Hybrid molecules of carvacrol and benzoyl urea/thiourea with potential applications in agriculture and medicine.
AID1111475	Reduction of fertility in 7 days old adult of Anastrepha serpentina assessed as reduction of egg hatching at 5 mg/g treated with diet measured after 9 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111483	Reduction of fertility in 7 days old adult of Anastrepha serpentina assessed as reduction of egg hatching at 1 mg/g treated with diet measured after 5 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111453	Reduction of fertility in 7 days old adult of Anastrepha striata assessed as reduction of egg hatching at 0.5 mg/g treated with diet measured after 5 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID677530	Insecticidal activity against 5th instar nymph of Dysdercus koenigii assessed as mortality per nymph	2012	Bioorganic & medicinal chemistry letters, Sep-01, Volume: 22, Issue:17	Hybrid molecules of carvacrol and benzoyl urea/thiourea with potential applications in agriculture and medicine.
AID677539	Antifungal activity against Candida albicans NCIM 3557 after 48 hrs by microbroth dilution method	2012	Bioorganic & medicinal chemistry letters, Sep-01, Volume: 22, Issue:17	Hybrid molecules of carvacrol and benzoyl urea/thiourea with potential applications in agriculture and medicine.
AID1111498	Reduction of fertility in 7 days old adult of Anastrepha obliqua assessed as reduction of egg hatching at 30 mg/g treated with diet measured after 11 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111410	Effect on fertility in 7 days old adult male of Anastrepha striata at 30 mg/g treated with diet after 24 hr in presence of untreated adult female of Anastrepha striata	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111513	Reduction of fertility in 7 days old adult of Anastrepha obliqua assessed as reduction of egg hatching at 5 mg/g treated with diet measured after 5 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111481	Reduction of fertility in 7 days old adult of Anastrepha serpentina assessed as reduction of egg hatching at 1 mg/g treated with diet measured after 9 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID677612	Antifungal activity against Candida glabrata NCIM 3237 after 48 hrs by microbroth dilution method	2012	Bioorganic & medicinal chemistry letters, Sep-01, Volume: 22, Issue:17	Hybrid molecules of carvacrol and benzoyl urea/thiourea with potential applications in agriculture and medicine.
AID1111488	Reduction of fertility in 7 days old adult of Anastrepha serpentina assessed as reduction of egg hatching at 0.5 mg/g treated with diet measured after 7 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111528	Reduction of fertility in 7 days old adult of Anastrepha obliqua assessed as reduction of egg hatching at 0.1 mg/g treated with diet measured after 11 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111413	Effect on fertility in 7 days old adult male of Anastrepha ludens at 30 mg/g treated with diet after 24 hr in presence of untreated adult female of Anastrepha ludens	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111573	Effect on fecundity in 7 days old adult of Anastrepha ludens at 0.1 to 30 mg/g treated with diet after 24 hr	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111422	Effect on fecundity in 7 days old adult female of Anastrepha striata at 30 mg/g treated with diet after 24 hr in presence of untreated adult male of Anastrepha striata	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111524	Reduction of fertility in 7 days old adult of Anastrepha obliqua assessed as reduction of egg hatching at 0.5 mg/g treated with diet measured after 7 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111509	Reduction of fertility in 7 days old adult of Anastrepha obliqua assessed as reduction of egg hatching at 10 mg/g treated with diet measured after 1 day oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111432	Reduction of fertility in 7 days old adult of Anastrepha striata assessed as reduction of egg hatching at 10 mg/g treated with diet measured after 11 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111485	Reduction of fertility in 7 days old adult of Anastrepha serpentina assessed as reduction of egg hatching at 1 mg/g treated with diet measured after 1 day oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111474	Reduction of fertility in 7 days old adult of Anastrepha serpentina assessed as reduction of egg hatching at 5 mg/g treated with diet measured after 11 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111416	Effect on fertility in 7 days old adult female of Anastrepha obliqua at 30 mg/g treated with diet after 24 hr in presence of untreated adult male of Anastrepha obliqua	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111502	Reduction of fertility in 7 days old adult of Anastrepha obliqua assessed as reduction of egg hatching at 30 mg/g treated with diet measured after 3 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111543	Reduction of fertility in 7 days old adult of Anastrepha ludens assessed as reduction of egg hatching at 10 mg/g treated with diet measured after 5 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111567	Reduction of fertility in 7 days old adult of Anastrepha ludens assessed as reduction of egg hatching at 0.1 mg/g treated with diet measured after 5 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111503	Reduction of fertility in 7 days old adult of Anastrepha obliqua assessed as reduction of egg hatching at 30 mg/g treated with diet measured after 1 day oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111571	Effect on fecundity in 7 days old adult of Anastrepha serpentina at 0.1 to 30 mg/g treated with diet after 24 hr	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111539	Reduction of fertility in 7 days old adult of Anastrepha ludens assessed as reduction of egg hatching at 30 mg/g treated with diet measured after 1 day oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111477	Reduction of fertility in 7 days old adult of Anastrepha serpentina assessed as reduction of egg hatching at 5 mg/g treated with diet measured after 5 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111426	Reduction of fertility in 7 days old adult of Anastrepha striata assessed as reduction of egg hatching at 30 mg/g treated with diet measured after 11 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111427	Reduction of fertility in 7 days old adult of Anastrepha striata assessed as reduction of egg hatching at 30 mg/g treated with diet measured after 7 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111533	Reduction of fertility in 7 days old adult of Anastrepha obliqua assessed as reduction of egg hatching at 0.1 mg/g treated with diet measured after 1 day oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111529	Reduction of fertility in 7 days old adult of Anastrepha obliqua assessed as reduction of egg hatching at 0.1 mg/g treated with diet measured after 9 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111428	Reduction of fertility in 7 days old adult of Anastrepha striata assessed as reduction of egg hatching at 30 mg/g treated with diet measured after 9 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111464	Reduction of fertility in 7 days old adult of Anastrepha serpentina assessed as reduction of egg hatching at 30 mg/g treated with diet measured after 7 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111506	Reduction of fertility in 7 days old adult of Anastrepha obliqua assessed as reduction of egg hatching at 10 mg/g treated with diet measured after 7 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111470	Reduction of fertility in 7 days old adult of Anastrepha serpentina assessed as reduction of egg hatching at 10 mg/g treated with diet measured after 7 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111546	Reduction of fertility in 7 days old adult of Anastrepha ludens assessed as reduction of egg hatching at 5 mg/g treated with diet measured after 11 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111469	Reduction of fertility in 7 days old adult of Anastrepha serpentina assessed as reduction of egg hatching at 10 mg/g treated with diet measured after 9 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111515	Reduction of fertility in 7 days old adult of Anastrepha obliqua assessed as reduction of egg hatching at 5 mg/g treated with diet measured after 1 day oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID977602	Inhibition of sodium fluorescein uptake in OATP1B3-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM	2013	Molecular pharmacology, Jun, Volume: 83, Issue:6	Structure-based identification of OATP1B1/3 inhibitors.
AID1111558	Reduction of fertility in 7 days old adult of Anastrepha ludens assessed as reduction of egg hatching at 0.5 mg/g treated with diet measured after 11 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111510	Reduction of fertility in 7 days old adult of Anastrepha obliqua assessed as reduction of egg hatching at 5 mg/g treated with diet measured after 11 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111449	Reduction of fertility in 7 days old adult of Anastrepha striata assessed as reduction of egg hatching at 1 mg/g treated with diet measured after 3 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111572	Effect on fecundity in 7 days old adult of Anastrepha obliqua at 0.1 to 30 mg/g treated with diet after 24 hr	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111419	Effect on fecundity in 7 days old adult male of Anastrepha serpentina at 30 mg/g treated with diet after 24 hr in presence of untreated adult female of Anastrepha serpentina	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111535	Reduction of fertility in 7 days old adult of Anastrepha ludens assessed as reduction of egg hatching at 30 mg/g treated with diet measured after 9 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111521	Reduction of fertility in 7 days old adult of Anastrepha obliqua assessed as reduction of egg hatching at 1 mg/g treated with diet measured after 1 day oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111496	Reduction of fertility in 7 days old adult of Anastrepha serpentina assessed as reduction of egg hatching at 0.1 mg/g treated with diet measured after 3 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111454	Reduction of fertility in 7 days old adult of Anastrepha striata assessed as reduction of egg hatching at 0.5 mg/g treated with diet measured after 3 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111504	Reduction of fertility in 7 days old adult of Anastrepha obliqua assessed as reduction of egg hatching at 10 mg/g treated with diet measured after 11 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111531	Reduction of fertility in 7 days old adult of Anastrepha obliqua assessed as reduction of egg hatching at 0.1 mg/g treated with diet measured after 5 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111418	Effect on fecundity in 7 days old adult male of Anastrepha striata at 30 mg/g treated with diet after 24 hr in presence of untreated adult female of Anastrepha striata	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111563	Reduction of fertility in 7 days old adult of Anastrepha ludens assessed as reduction of egg hatching at 0.5 mg/g treated with diet measured after 1 day oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111468	Reduction of fertility in 7 days old adult of Anastrepha serpentina assessed as reduction of egg hatching at 10 mg/g treated with diet measured after 11 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111538	Reduction of fertility in 7 days old adult of Anastrepha ludens assessed as reduction of egg hatching at 30 mg/g treated with diet measured after 3 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111412	Effect on fertility in 7 days old adult male of Anastrepha obliqua at 30 mg/g treated with diet after 24 hr in presence of untreated adult female of Anastrepha obliqua	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111473	Reduction of fertility in 7 days old adult of Anastrepha serpentina assessed as reduction of egg hatching at 10 mg/g treated with diet measured after 1 day oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111516	Reduction of fertility in 7 days old adult of Anastrepha obliqua assessed as reduction of egg hatching at 1 mg/g treated with diet measured after 11 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111547	Reduction of fertility in 7 days old adult of Anastrepha ludens assessed as reduction of egg hatching at 5 mg/g treated with diet measured after 9 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111495	Reduction of fertility in 7 days old adult of Anastrepha serpentina assessed as reduction of egg hatching at 0.1 mg/g treated with diet measured after 5 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111501	Reduction of fertility in 7 days old adult of Anastrepha obliqua assessed as reduction of egg hatching at 30 mg/g treated with diet measured after 5 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111542	Reduction of fertility in 7 days old adult of Anastrepha ludens assessed as reduction of egg hatching at 10 mg/g treated with diet measured after 7 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111424	Effect on fecundity in 7 days old adult female of Anastrepha obliqua at 30 mg/g treated with diet after 24 hr in presence of untreated adult male of Anastrepha obliqua	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111517	Reduction of fertility in 7 days old adult of Anastrepha obliqua assessed as reduction of egg hatching at 1 mg/g treated with diet measured after 9 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID677611	Antifungal activity against Candida albicans NCIM 3471 after 48 hrs by microbroth dilution method	2012	Bioorganic & medicinal chemistry letters, Sep-01, Volume: 22, Issue:17	Hybrid molecules of carvacrol and benzoyl urea/thiourea with potential applications in agriculture and medicine.
AID1111425	Effect on fecundity in 7 days old adult female of Anastrepha ludens at 30 mg/g treated with diet after 24 hr in presence of untreated adult male of Anastrepha ludens	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111458	Reduction of fertility in 7 days old adult of Anastrepha striata assessed as reduction of egg hatching at 0.1 mg/g treated with diet measured after 7 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111494	Reduction of fertility in 7 days old adult of Anastrepha serpentina assessed as reduction of egg hatching at 0.1 mg/g treated with diet measured after 7 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111497	Reduction of fertility in 7 days old adult of Anastrepha serpentina assessed as reduction of egg hatching at 0.1 mg/g treated with diet measured after 1 day oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111536	Reduction of fertility in 7 days old adult of Anastrepha ludens assessed as reduction of egg hatching at 30 mg/g treated with diet measured after 7 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID977599	Inhibition of sodium fluorescein uptake in OATP1B1-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM	2013	Molecular pharmacology, Jun, Volume: 83, Issue:6	Structure-based identification of OATP1B1/3 inhibitors.
AID1111530	Reduction of fertility in 7 days old adult of Anastrepha obliqua assessed as reduction of egg hatching at 0.1 mg/g treated with diet measured after 7 days oviposition	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1111415	Effect on fertility in 7 days old adult female of Anastrepha serpentina at 30 mg/g treated with diet after 24 hr in presence of untreated adult male of Anastrepha serpentina	2010	Pest management science, Jun, Volume: 66, Issue:6	Evaluation of lufenuron as a chemosterilant against fruit flies of the genus Anastrepha (Diptera: Tephritidae).
AID1296008	Cytotoxic Profiling of Annotated Libraries Using Quantitative High-Throughput Screening	2020	SLAS discovery : advancing life sciences R & D, 01, Volume: 25, Issue:1	Cytotoxic Profiling of Annotated and Diverse Chemical Libraries Using Quantitative High-Throughput Screening.
AID1346986	P-glycoprotein substrates identified in KB-3-1 adenocarcinoma cell line, qHTS therapeutic library screen	2019	Molecular pharmacology, 11, Volume: 96, Issue:5	A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
AID1346987	P-glycoprotein substrates identified in KB-8-5-11 adenocarcinoma cell line, qHTS therapeutic library screen	2019	Molecular pharmacology, 11, Volume: 96, Issue:5	A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
AID1347091	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for SJ-GBM2 cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347102	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for Rh18 cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347099	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for NB1643 cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347089	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for TC32 cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347083	qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lassa (LASV) Arenavirus: Viability assay - alamar blue signal for LASV Primary Screen	2020	Antiviral research, 01, Volume: 173	A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity.
AID1347095	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for NB-EBc1 cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347096	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for U-2 OS cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347098	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for SK-N-SH cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347100	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for LAN-5 cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347103	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for OHS-50 cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347154	Primary screen GU AMC qHTS for Zika virus inhibitors	2020	Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49	Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
AID1347106	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for control Hh wild type fibroblast cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347101	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for BT-12 cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347094	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for BT-37 cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347425	Rhodamine-PBP qHTS Assay for Modulators of WT P53-Induced Phosphatase 1 (WIP1)	2019	The Journal of biological chemistry, 11-15, Volume: 294, Issue:46	Physiologically relevant orthogonal assays for the discovery of small-molecule modulators of WIP1 phosphatase in high-throughput screens.
AID1347407	qHTS to identify inhibitors of the type 1 interferon - major histocompatibility complex class I in skeletal muscle: primary screen against the NCATS Pharmaceutical Collection	2020	ACS chemical biology, 07-17, Volume: 15, Issue:7	High-Throughput Screening to Identify Inhibitors of the Type I Interferon-Major Histocompatibility Complex Class I Pathway in Skeletal Muscle.
AID651635	Viability Counterscreen for Primary qHTS for Inhibitors of ATXN expression
AID1347090	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for DAOY cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347108	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for Rh41 cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347104	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for RD cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347092	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for A673 cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1745845	Primary qHTS for Inhibitors of ATXN expression
AID1347105	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for MG 63 (6-TG R) cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347086	qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lymphocytic Choriomeningitis Arenaviruses (LCMV): LCMV Primary Screen - GLuc reporter signal	2020	Antiviral research, 01, Volume: 173	A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity.
AID1347107	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for Rh30 cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347424	RapidFire Mass Spectrometry qHTS Assay for Modulators of WT P53-Induced Phosphatase 1 (WIP1)	2019	The Journal of biological chemistry, 11-15, Volume: 294, Issue:46	Physiologically relevant orthogonal assays for the discovery of small-molecule modulators of WIP1 phosphatase in high-throughput screens.
AID1347082	qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lassa (LASV) Arenavirus: LASV Primary Screen - GLuc reporter signal	2020	Antiviral research, 01, Volume: 173	A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity.
AID1347097	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for Saos-2 cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347093	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for SK-N-MC cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1508630	Primary qHTS for small molecule stabilizers of the endoplasmic reticulum resident proteome: Secreted ER Calcium Modulated Protein (SERCaMP) assay	2021	Cell reports, 04-27, Volume: 35, Issue:4	A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome.
AID504749	qHTS profiling for inhibitors of Plasmodium falciparum proliferation	2011	Science (New York, N.Y.), Aug-05, Volume: 333, Issue:6043	Chemical genomic profiling for antimalarial therapies, response signatures, and molecular targets.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	0 (0.00)	18.7374
1990's	22 (15.71)	18.2507
2000's	48 (34.29)	29.6817
2010's	50 (35.71)	24.3611
2020's	20 (14.29)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Publication Type	This drug (%)	All Drugs (%)
Trials	16 (11.27%)	5.53%
Reviews	2 (1.41%)	6.00%
Case Studies	4 (2.82%)	4.05%
Observational	0 (0.00%)	0.25%
Other	120 (84.51%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Trials	Classes	Roles
acetic acid Acetic Acid: Product of the oxidation of ethanol and of the destructive distillation of wood. It is used locally, occasionally internally, as a counterirritant and also as a reagent. (Stedman, 26th ed). acetic acid : A simple monocarboxylic acid containing two carbons.	2.11	1	0	monocarboxylic acid	antimicrobial food preservative; Daphnia magna metabolite; food acidity regulator; protic solvent
carbamates [no description available]	2.05	1	0	amino-acid anion
methanol Methanol: A colorless, flammable liquid used in the manufacture of FORMALDEHYDE and ACETIC ACID, in chemical synthesis, antifreeze, and as a solvent. Ingestion of methanol is toxic and may cause blindness.. primary alcohol : A primary alcohol is a compound in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it.. methanol : The primary alcohol that is the simplest aliphatic alcohol, comprising a methyl and an alcohol group.	2.1	1	0	alkyl alcohol; one-carbon compound; primary alcohol; volatile organic compound	amphiprotic solvent; Escherichia coli metabolite; fuel; human metabolite; mouse metabolite; Mycoplasma genitalium metabolite
niacinamide nicotinamide : A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group.	2.52	2	0	pyridine alkaloid; pyridinecarboxamide; vitamin B3	anti-inflammatory agent; antioxidant; cofactor; EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor; EC 3.5.1.98 (histone deacetylase) inhibitor; Escherichia coli metabolite; geroprotector; human urinary metabolite; metabolite; mouse metabolite; neuroprotective agent; Saccharomyces cerevisiae metabolite; Sir2 inhibitor
pteridines [no description available]	1.99	1	0	azaarene; mancude organic heterobicyclic parent; ortho-fused heteroarene; pteridines
albendazole [no description available]	2.42	2	0	aryl sulfide; benzimidazoles; benzimidazolylcarbamate fungicide; carbamate ester	anthelminthic drug; microtubule-destabilising agent; tubulin modulator
amlodipine Amlodipine: A long-acting dihydropyridine calcium channel blocker. It is effective in the treatment of ANGINA PECTORIS and HYPERTENSION.. amlodipine : A fully substituted dialkyl 1,4-dihydropyridine-3,5-dicarboxylate derivative, which is used for the treatment of hypertension, chronic stable angina and confirmed or suspected vasospastic angina.	2.6	1	0	dihydropyridine; ethyl ester; methyl ester; monochlorobenzenes; primary amino compound	antihypertensive agent; calcium channel blocker; vasodilator agent
fenthion Fenthion: Potent cholinesterase inhibitor used as an insecticide and acaricide.. fenthion : An organic thiophosphate that is O,O-dimethyl hydrogen phosphorothioate in which the hydrogen atom of the hydroxy group is replaced by a 3-methyl-4-(methylsulfanyl)phenyl group. It exhibits acaricidal and insecticidal activities.	3.37	1	1	organic thiophosphate	acaricide; agrochemical; avicide; EC 3.1.1.7 (acetylcholinesterase) inhibitor; EC 3.1.1.8 (cholinesterase) inhibitor; insecticide
fipronil fipronil: has low mammalian toxicity; structure given in first source. fipronil : A racemate comprising equimolar amounts of (R)- and (S)-fipronil.. 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfinyl]-1H-pyrazole-3-carbonitrile : A member of the class of pyrazoles that is 1H-pyrazole that is substituted at positions 1, 3, 4, and 5 by 2,6-dichloro-4-(trifluoromethyl)phenyl, cyano, (trifluoromethyl)sulfinyl, and amino groups, respectively.	3.51	2	0	(trifluoromethyl)benzenes; dichlorobenzene; nitrile; primary amino compound; pyrazoles; sulfoxide
malathion Malathion: A wide spectrum aliphatic organophosphate insecticide widely used for both domestic and commercial agricultural purposes.. malathion : A racemate comprising equimolar amounts of (R) and (S)-malathion. It is a broad spectrum organophosphate proinsecticide used to control a wide range of pests including Coleoptera, Diptera, fruit flies, mosquitos and spider mites.. diethyl 2-[(dimethoxyphosphorothioyl)thio]succinate : A diester that is diethyl succinate in which position 2 is substituted by a (dimethoxyphosphorothioyl)thio group.	2.45	2	0	diester; ethyl ester; organic thiophosphate
methomyl Methomyl: A carbamate insecticide with anticholinesterase activity.. methomyl : A carbamate ester obtained by the formal condensation of methylcarbamic acid with the hydroxy group of 1-(methylsulfanyl)acetaldoxime.	2.17	1	0	aliphatic sulfide; carbamate ester	acaricide; agrochemical; EC 3.1.1.7 (acetylcholinesterase) inhibitor; EC 3.1.1.8 (cholinesterase) inhibitor; environmental contaminant; insecticide; nematicide; xenobiotic
phosalone phosalone: structure. phosalone : A member of the class of 1,3-benzoxazoles carrying a [(diethoxyphosphorothioyl)sulfanyl]methyl group at the nitrogen atom, an oxo group at position 2 and a chloro group at position 6. It is an organothiophosphate insecticide.	2.03	1	0	1,3-benzoxazoles; carbamate ester; organochlorine insecticide; organothiophosphate insecticide	acaricide; agrochemical; EC 3.1.1.7 (acetylcholinesterase) inhibitor; EC 3.1.1.8 (cholinesterase) inhibitor
prometryne Prometryne: A triazine used as a selective pre- and post-emergence herbicide. (From Merck Index, 11th ed). prometryn : A diamino-1,3,5-triazine that is N,N'-di(propan-2-yl)-1,3,5-triazine-2,4-diamine substituted by a methylsulfanediyl group at position 6.	2.06	1	0	diamino-1,3,5-triazine; methylthio-1,3,5-triazine	environmental contaminant; herbicide; xenobiotic
propoxur Propoxur: A carbamate insecticide.. propoxur : A carbamate ester that is phenyl methylcarbamate substituted at position 2 by a propan-2-yloxy group.	2.4	2	0	aromatic ether; carbamate ester	acaricide; agrochemical; carbamate insecticide; EC 3.1.1.7 (acetylcholinesterase) inhibitor
alanine Alanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.. alanine : An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2.	2.02	1	0	alanine zwitterion; alanine; L-alpha-amino acid; proteinogenic amino acid; pyruvate family amino acid	EC 4.3.1.15 (diaminopropionate ammonia-lyase) inhibitor; fundamental metabolite
acetonitrile acetonitrile: RN given refers to unlabeled cpd. acetonitrile : A nitrile that is hydrogen cyanide in which the hydrogen has been replaced by a methyl group.	2.11	1	0	aliphatic nitrile; volatile organic compound	EC 3.5.1.4 (amidase) inhibitor; NMR chemical shift reference compound; polar aprotic solvent
pyrroles 1H-pyrrole : A tautomer of pyrrole that has the double bonds at positions 2 and 4.. pyrrole : A five-membered monocyclic heteroarene comprising one NH and four CH units which forms the parent compound of the pyrrole group of compounds. Its five-membered ring structure has three tautomers. A 'closed class'.. azole : Any monocyclic heteroarene consisting of a five-membered ring containing nitrogen. Azoles can also contain one or more other non-carbon atoms, such as nitrogen, sulfur or oxygen.	2.06	1	0	pyrrole; secondary amine
hydrazine diamine : Any polyamine that contains two amino groups.	3.04	4	0	azane; hydrazines	EC 4.3.1.10 (serine-sulfate ammonia-lyase) inhibitor
carvacrol carvacrol : A phenol that is a natural monoterpene derivative of cymene. An inhibitor of bacterial growth, it is used as a food additive. Potent activator of the human ion channels transient receptor potential V3 (TRPV3) and A1 (TRPA1).	2.07	1	0	botanical anti-fungal agent; p-menthane monoterpenoid; phenols	agrochemical; antimicrobial agent; flavouring agent; TRPA1 channel agonist; volatile oil component
carbamothioic acid, s,s'-(2-(dimethylamino)-1,3-propanediyl) ester carbamothioic acid, S,S'-(2-(dimethylamino)-1,3-propanediyl) ester: RN given refers to parent cpd; Padan refers to mono-HCl	2.17	1	0	nereistoxin analogue insecticide
chlortoluron chlorotoluron : A member of the class of phenylureas that is urea in which one of the nitrogens is substituted by two methyl groups while the other is substituted by a 3-chloro-4-methylphenyl group. A herbicide that is non-toxic to honeybees but moderately toxic to mammals, birds, earthworms and most aquatic organisms.	2.06	1	0	monochlorobenzenes; phenylureas	agrochemical; environmental contaminant; herbicide; xenobiotic
diflubenzuron Diflubenzuron: An insect growth regulator which interferes with the formation of the insect cuticle. It is effective in the control of mosquitoes and flies.. diflubenzuron : A benzoylurea insecticide that is urea in which a hydrogen attached to one of the nitrogens is replaced by a 4-chlorophenyl group, and a hydrogen attached to the other nitrogen is replaced bgy a 2,6-difluorobenzoyl group.	4.42	6	0	benzoylurea insecticide; monochlorobenzenes	insect sterilant
enilconazole enilconazole: RN given refers to parent cpd. enilconazole : A racemate comprising equimolar amounts of (R)- and (S)-enilconazole. A fungicide used to control a wide range of fungi including Tilletia and Helminthosporium spp. on fruit, vegetables and ornamentals. In veterinary medicine, it is used topically for the treatment of fungal skin infections in cattle, dogs, and horses; it is also used by inhalation for the treatment of aspergillosis in ostriches.. 1-[2-(allyloxy)-2-(2,4-dichlorophenyl)ethyl]imidazole : A member of the class of imidazoles in which the hydrogen at position 1 is replaced by a 2-(allyloxy)-2-(2,4-dichlorophenyl)ethyl group.	3.82	2	1	dichlorobenzene; ether; imidazoles
decamethrin decamethrin: pyrethroid insecticide; RN given refers to cpd without isomeric designation; structure	2.82	3	0	aromatic ether; cyclopropanecarboxylate ester; nitrile; organobromine compound	agrochemical; antifeedant; calcium channel agonist; EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor; pyrethroid ester insecticide
metalaxyl metalaxyl: RN given refers to (DL-Ala)-isomer. metalaxyl : A racemate comprising equal amounts of (R)- and (S)-metalaxyl. A systemic fungicide, it is active against phytopathogens of the order Peronosporales and is used to conrtrol Pythium in a number of vegetable crops.. methyl N-(2,6-dimethylphenyl)-N-(methoxyacetyl)alaninate : An alanine derivative that is methyl alaninate in which one of the hydrogens attached to the nitrogen is substituted by a methoxyacetyl group, while the other is substituted by a 2,6-dimethylphenyl group.	2.02	1	0	alanine derivative; aromatic amide; carboxamide; ether; methyl ester
propiconazole Orbit: Bony cavity that holds the eyeball and its associated tissues and appendages.	2.06	1	0	conazole fungicide; cyclic ketal; dichlorobenzene; triazole fungicide; triazoles	antifungal agrochemical; EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor; environmental contaminant; xenobiotic
triflumuron triflumuron: insect growth inhibitor	2.73	3	0	aromatic ether; benzoylurea insecticide; monochlorobenzenes; organofluorine compound
cyromazine cyromazine: RN given refers to parent cpd	2.96	4	0	triamino-1,3,5-triazine	mouse metabolite; triazine insecticide
buprofezin buprofezin: tradename - Applaud; used for the control of homopterous insect pests; structure given in first source. (E)-buprofezin : A 2-(tert-butylimino)-5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one in which the C=N double bond has E configuration.. buprofezin : A 2-(tert-butylimino)-5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one in which the C=N double bond has Z configuration.	2.51	2	0	thiadiazinane; ureas
fenoxycarb fenoxycarb: used against mosquitoes (Diptera:Culicidae); structure given in first source. fenoxycarb : A carbamate ester that is the O-ethyl carbamate of 2-(4-phenoxyphenoxy)ethylamine.	2.74	3	0	aromatic ether; carbamate ester	environmental contaminant; insecticide; juvenile hormone mimic; xenobiotic
itraconazole Itraconazole: A triazole antifungal agent that inhibits cytochrome P-450-dependent enzymes required for ERGOSTEROL synthesis.. itraconazole : An N-arylpiperazine that is cis-ketoconazole in which the imidazol-1-yl group is replaced by a 1,2,4-triazol-1-yl group and in which the actyl group attached to the piperazine moiety is replaced by a p-[(+-)1-sec-butyl-5-oxo-1,5-dihydro-4H-1,2,4-triazol-4-yl]phenyl group. A potent P-glycoprotein and CYP3A4 inhibitor, it is used as an antifungal drug for the treatment of various fungal infections, including aspergillosis, blastomycosis, candidiasis, chromoblastomycosis, coccidioidomycosis, cryptococcosis, histoplasmosis, and sporotrichosis.	2.5	2	0	aromatic ether; conazole antifungal drug; cyclic ketal; dichlorobenzene; dioxolane; N-arylpiperazine; triazole antifungal drug; triazoles	EC 3.6.3.44 (xenobiotic-transporting ATPase) inhibitor; Hedgehog signaling pathway inhibitor; P450 inhibitor
fluazuron fluazuron: a benzoyl phenylurea compound; ACATAK (tradename) is a pour-on tick development inhibitor containing fluazuron as its active ingredient. fluazuron : An N-acylurea that is urea in which one of the hydrogens has been replaced by a 3,6-difluorobenzoyl group, while a hydrogen attached to the other nitrogen has been replaced by a 4-chloro-3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenyl group. It is used to control ticks in cattle.	2.04	1	0	aromatic ether; chloropyridine; monochlorobenzenes; N-acylurea; organochlorine acaricide; organofluorine acaricide; phenylureas	acaricide; mite growth regulator
triazoles Triazoles: Heterocyclic compounds containing a five-membered ring with two carbon atoms and three nitrogen atoms with the molecular formula C2H3N3.. triazoles : An azole in which the five-membered heterocyclic aromatic skeleton contains three N atoms and two C atoms.	2.06	1	0	1,2,3-triazole
fludioxonil fludioxonil: structure in first source. fludioxonil : A member of the class of benzodioxoles that is 2,2-difluoro-1,3-benzodioxole substituted at position 4 by a 3-cyanopyrrol-4-yl group. A fungicide seed treatment for control of a range of diseases including Fusarium, Rhizoctonia and Alternaria.	2.06	1	0	benzodioxoles; nitrile; organofluorine compound; pyrroles	androgen antagonist; antifungal agrochemical; estrogen receptor agonist
chlorfluazuron chlorfluazuron: chitin synthesis inhibitor	2.21	1	0	benzoylurea insecticide; dichlorobenzene; organochlorine insecticide; organofluorine insecticide
teflubenzuron teflubenzuron: effective against development of house fly larvae (Musca domestica). teflubenzuron : A N-acylurea that is N-carbamoyl-2,6-difluorobenzamide substituted by a 3,5-dichloro-2,4-difluorophenyl group at the terminal nitrogen atom.	3.05	4	0	dichlorobenzene; difluorobenzene; N-acylurea	environmental contaminant; insecticide; xenobiotic
hexafluoron hexafluoron: insect growth regulator against mosquito larva; the active agent in Sonet, a Russian product, is hexaflumuron. hexaflumuron : An N-acylurea that is urea in which a hydrogen attached to one of the nitrogens is replaced by a 2,6-difluorobenzoyl group, while a hycrogen attached to the other nitorgen is replaced by a 3,5-dichloro-4-(1,1,2,2-tetrafluoroethoxy)phenyl group.	3.48	7	0	aromatic ether; benzoylurea insecticide; dichlorobenzene; N-acylurea; organochlorine insecticide; organofluorine insecticide
pyriproxyfen pyriproxyfen: an insect growth regulator; RN given refers to cpd without isomeric designation. pyriproxyfen : An aromatic ether that consists of propylene glycol having a 2-pyridyl group at the O-1 position and a 4-phenoxyphenyl group at the O-3 position.	5.04	9	1	aromatic ether; pyridines	juvenile hormone mimic
flufenoxuron [no description available]	3.56	8	0	(trifluoromethyl)benzenes; benzoylurea insecticide; difluorobenzene; monochlorobenzenes; monofluorobenzenes	mite growth regulator
tebufenozide tebufenozide: structure given in first source. tebufenozide : A carbohydrazide that is hydrazine in which the amino hydrogens have been replaced by tert-butyl, 3,5-dimethylbenzoyl and 4-ethylbenzoyl groups respectively. It is an insecticide used widely against caterpillars.	2.06	1	0	carbohydrazide	ecdysone agonist; environmental contaminant; xenobiotic
methoxyfenozide methoxyfenozide: structure in first source. methoxyfenozide : A carbohydrazide that is hydrazine in which the amino hydrogens have been replaced by 3-methoxy-2-methylbenzoyl, 3,5-dimethylbenzoyl, and tert-butyl groups respectively.	3.12	4	0	carbohydrazide; monomethoxybenzene	environmental contaminant; insecticide; xenobiotic
indoxacarb indoxacarb: oxadiazine insecticide; structure in first source. insecticide : Strictly, a substance intended to kill members of the class Insecta. In common usage, any substance used for preventing, destroying, repelling or controlling insects.	2.66	2	0	methyl ester; organochlorine insecticide	voltage-gated sodium channel blocker
pinoxaden pinoxaden: structure in first source. pinoxaden : A pyrazolooxadiazepine that is 7-oxo-1,2,4,5-tetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepin which is substituted at positions 8 and 9 by 2,6-diethyl-4-methylphenyl and pivaloyloxy groups, respectively. A pro-herbicide (by hydrolysis of the pivalate ester to give the corresponding enol), it is used for control of grass weeds in cereal crops.	2.06	1	0	pivalate ester; pyrazolooxadiazepine	agrochemical; EC 6.4.1.2 (acetyl-CoA carboxylase) inhibitor; environmental contaminant; proherbicide; xenobiotic
erythritol [no description available]	2.15	1	0	butane-1,2,3,4-tetrol	antioxidant; human metabolite; plant metabolite
o-(chloroacetylcarbamoyl)fumagillol O-(Chloroacetylcarbamoyl)fumagillol: Semisynthetic analog of fumagillin (a cyclohexane-sesquiterpene antibiotic isolated from ASPERGILLUS FUMIGATUS) that inhibits angiogenesis.. O-(chloroacetylcarbamoyl)fumagillol : A carbamate ester that is fumagillol in which the hydroxy group has been converted to the corresponding N-(chloroacetyl)carbamate derivative.	1.99	1	0	carbamate ester; organochlorine compound; semisynthetic derivative; sesquiterpenoid; spiro-epoxide	angiogenesis inhibitor; antineoplastic agent; EC 1.5.1.3 (dihydrofolate reductase) inhibitor; methionine aminopeptidase 2 inhibitor; retinoic acid receptor alpha antagonist
epiglucan epiglucan: a highly side-chain/branched alkali-insoluble cell wall glucan from fungus such as Epicoccum nigrum, Botrytis cinerea, ascomycetes & basidiomycetes; also isolated S-4001 from Lei Wan (polyporus mylitiae), HA-beta-glucan from mushroom Pleutotus ostreatus (Fr.) Quel., and translam from seaweed Laminaria cichorioides; with commercially important functional properties including emulsification and friction reduction.	2.07	1	0
griseofulvin Griseofulvin: An antifungal agent used in the treatment of TINEA infections.. griseofulvin : An oxaspiro compound produced by Penicillium griseofulvum. It is used by mouth as an antifungal drug for infections involving the scalp, hair, nails and skin that do not respond to topical treatment.	2.05	1	0	1-benzofurans; antibiotic antifungal drug; benzofuran antifungal drug; organochlorine compound; oxaspiro compound	antibacterial agent; Penicillium metabolite
l 743,872 [no description available]	2.07	1	0
sesquiterpenes [no description available]	1.99	1	0
1-octyl-3-methylimidazolium hexafluorophosphate 1-octyl-3-methylimidazolium hexafluorophosphate: is a nonaqueous ionic liquid	2.1	1	0
nitenpyram nitenpyram: a nitromethylene neonicotinoid insecticide; structure in first source. (E)-nitenpyram : A nitenpyram in which the double bond has E configuration.. nitenpyram : A C-nitro compound consisting of 2-nitroethene-1,1-diamine where one of the nitrogens bears ethyl and (6-chloro-3-pyridinyl)methyl while the other nitrogen carries a methyl group.	4.12	3	1	chloropyridyl insecticide; nitenpyram
amphotericin b Amphotericin B: Macrolide antifungal antibiotic produced by Streptomyces nodosus obtained from soil of the Orinoco river region of Venezuela.. amphotericin B : A macrolide antibiotic used to treat potentially life-threatening fungal infections.	2.07	1	0	antibiotic antifungal drug; macrolide antibiotic; polyene antibiotic	antiamoebic agent; antiprotozoal drug; bacterial metabolite
azadirachtin azadirachtin A : A member of the family of azadirachtins that is isolated from the neem tree (Azadirachta indica).. azadirachtin : A family of terpenoids isolated from the neem tree (Azadirachta indica).	2.08	1	0	acetate ester; azadirachtin; cyclic hemiketal; enoate ester; epoxide; methyl ester; organic heterotetracyclic compound; secondary alcohol; tertiary alcohol	hepatoprotective agent
cyhalothrin cyhalothrin: acaricidal & insecticidal synthetic pyrethroid; structure given in first source. cyhalothrin : A carboxylic ester obtained by formal condensation between 3-(2-chloro-3,3,3-trifluoroprop-1-en-1-yl)-2,2-dimethylcyclopropanecarboxylic acid and cyano(3-phenoxyphenyl)methanol.	2.49	2	0	aromatic ether; cyclopropanecarboxylate ester; nitrile; organochlorine compound; organofluorine compound	agrochemical; pyrethroid ester acaricide; pyrethroid ester insecticide
methoprene Methoprene: Juvenile hormone analog and insect growth regulator used to control insects by disrupting metamorphosis. Has been effective in controlling mosquito larvae.	2.4	2	0	isopropyl 11-methoxy-3,7,11-trimethyldodeca-2,4-dienoate; isopropyl ester	juvenile hormone mimic
zr-512 ethyl-3,7,11-trimethyl-2,4-dodecadienoate: an insect growth regulator; RN given refers to (E,E)-isomer. hydroprene : The ethyl ester of (2E,4E)-3,7,11-trimethyldodeca-2,4-dienoic acid	2.17	1	0	ethyl ester; farnesane sesquiterpenoid	juvenile hormone mimic
pyrachlostrobin pyraclostrobin : A carbamate ester that is the methyl ester of [2-({[1-(4-chlorophenyl)-1H-pyrazol-3-yl]oxy}methyl)phenyl]methoxycarbamic acid. A fungicide used to control major plant pathogens including Septoria tritici, Puccinia spp. and Pyrenophora teres.	2.05	1	0	aromatic ether; carbamate ester; carbanilate fungicide; methoxycarbanilate strobilurin antifungal agent; monochlorobenzenes; pyrazoles	antifungal agrochemical; environmental contaminant; mitochondrial cytochrome-bc1 complex inhibitor; xenobiotic
fumagillin [no description available]	1.99	1	0	antibiotic antifungal drug; carboxylic ester; dicarboxylic acid monoester; meroterpenoid; organooxygen heterocyclic antibiotic; spiro-epoxide	angiogenesis inhibitor; antibacterial drug; antimicrobial agent; antiprotozoal drug; fungal metabolite; methionine aminopeptidase 2 inhibitor
nikkomycin [no description available]	2.74	3	0
noviflumuron noviflumuron: structure in first source	2.05	1	0	aromatic ether; benzoylurea insecticide; dichlorobenzene; organofluorine compound
flonicamid flonicamid: an insecticide; structure in first source. flonicamid : A pyridinecarboxamide that is nicotinamide substituted by a trifluoromethyl group at position 4 and a cyanomethyl group at the carbamoyl nitrogen atom.	2.25	1	0	nitrile; organofluorine compound; pyridinecarboxamide	environmental contaminant; insecticide; xenobiotic
flubendiamide flubendiamide: activates ryanodine-sensitive calcium release channels in insects; structure in first source	2.61	2	0	organofluorine insecticide	ryanodine receptor modulator
chlorantranilipole chlorantranilipole: anthranilic diamide insecticide.that disrupts mating in codling moth (Lepidoptera: Tortricidae). chlorantraniliprole : A carboxamide resulting from the formal condensation of the carboxylic acid group of 3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxylic acid with the primary amino group of 2-amino-5-chloro-N,3-dimethylbenzamide. The first of the anthranilic diamide insecticides, it is a ryanodine receptor activator and is used to protect a wide variety of crops, including corn, cotton, grapes, rice and potatoes.	2.17	1	0	monochlorobenzenes; organobromine compound; pyrazole insecticide; pyrazoles; pyridines; secondary carboxamide	ryanodine receptor agonist
emamectin benzoate emamectin benzoate: 4'-deoxy-4'-epi-methylamino derivative of avermectin B1; structure given in first source. emamectin : A mixture of emamectin B1a (major component) and emamectin B1b (minor component).	2.11	1	0	emamectins
dextrothyroxine [no description available]	5.21	3	1
pyrethrins [no description available]	4.55	5	1
moxidectin moxidectin: family of macrolide antibiotics with insecticidal & acaricidal activity	4.36	2	2
selamectin selamectin: a broad-spectrum endectocide; structure in first source	4.9	2	1
imidacloprid imidacloprid: systemic & contact insecticide exhibiting low mammalian toxicity; structure given in first source; it is one of the neonicotinoid insecticides, which acts as an antagonist by binding to postsynaptic nicotinic receptors in the insect central nervous system. imidacloprid : An imidazolidine that is N-nitroimidazolidin-2-imine bearing a (6-chloro-3-pyridinyl)methyl substituent at position 1.	6.5	5	3	imidacloprid; imidazolidines; monochloropyridine	environmental contaminant; genotoxin; neonicotinoid insectide; nicotinic acetylcholine receptor agonist; xenobiotic

Condition	Relationship Strength	Studies	Trials
Fungal Diseases [description not available]	2.93	4	0
Mycoses Diseases caused by FUNGI.	2.93	4	0
Congenital Zika Syndrome [description not available]	2.25	1	0
Disease Models, Animal Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.	2.25	1	0
Zika Virus Infection A viral disease transmitted by the bite of AEDES mosquitoes infected with ZIKA VIRUS. Its mild DENGUE-like symptoms include fever, rash, headaches and ARTHRALGIA. The viral infection during pregnancy, in rare cases, is associated with congenital brain and ocular abnormalities, called Congenital Zika Syndrome, including MICROCEPHALY and may also lead to GUILLAIN-BARRE SYNDROME.	2.25	1	0
Sterility, Male [description not available]	2.41	1	0
Infertility, Male The inability of the male to effect FERTILIZATION of an OVUM after a specified period of unprotected intercourse. Male sterility is permanent infertility.	2.41	1	0
Black Death [description not available]	2.75	3	0
Rodent Diseases Diseases of rodents of the order RODENTIA. This term includes diseases of Sciuridae (squirrels), Geomyidae (gophers), Heteromyidae (pouched mice), Castoridae (beavers), Cricetidae (rats and mice), Muridae (Old World rats and mice), Erethizontidae (porcupines), and Caviidae (guinea pigs).	2.6	1	0
Flea Infestations Parasitic attack by members of the order SIPHONAPTERA.	2.6	1	0
Plague An acute infectious disease caused by YERSINIA PESTIS that affects humans, wild rodents, and their ectoparasites. This condition persists due to its firm entrenchment in sylvatic rodent-flea ecosystems throughout the world. Bubonic plague is the most common form.	2.75	3	0
Acute Myelogenous Leukemia [description not available]	2.6	1	0
Leukemia, Myeloid, Acute Clonal expansion of myeloid blasts in bone marrow, blood, and other tissue. Myeloid leukemias develop from changes in cells that normally produce NEUTROPHILS; BASOPHILS; EOSINOPHILS; and MONOCYTES.	2.6	1	0
Pregnancy The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.	2.25	1	0
Fish Diseases Diseases of freshwater, marine, hatchery or aquarium fish. This term includes diseases of both teleosts (true fish) and elasmobranchs (sharks, rays and skates).	2.17	1	0
Pediculosis [description not available]	2.17	1	0
Lice Infestations Parasitic attack or subsistence on the skin by members of the order Phthiraptera, especially on humans by Pediculus humanus of the family Pediculidae. The hair of the head, eyelashes, and pubis is a frequent site of infestation. (From Dorland, 28th ed; Stedman, 26th ed)	2.17	1	0
Parasitic Diseases, Animal Animal diseases caused by PARASITES.	3.35	2	0
Dermatomycoses Superficial infections of the skin or its appendages by any of various fungi.	5.82	8	3
Cat Diseases Diseases of the domestic cat (Felis catus or F. domesticus). This term does not include diseases of the so-called big cats such as CHEETAHS; LIONS; tigers, cougars, panthers, leopards, and other Felidae for which the heading CARNIVORA is used.	8.92	25	10
Ectoparasitic Infestations Infestations by PARASITES which live on, or burrow into, the surface of their host's EPIDERMIS. Most ectoparasites are ARTHROPODS.	7.52	17	9
Canine Diseases [description not available]	8.33	17	8
Cystic Echinococcosis [description not available]	2.06	1	0
Recrudescence [description not available]	2.01	1	0
Aspergillus Infection [description not available]	2.01	1	0
Candida Infection [description not available]	2.41	2	0
Endomyometritis Inflammation of both the ENDOMETRIUM and the MYOMETRIUM, usually caused by infections after a CESAREAN SECTION.	2.01	1	0
Equine Diseases [description not available]	2.01	1	0
Aspergillosis Infections with fungi of the genus ASPERGILLUS.	2.01	1	0
Candidiasis Infection with a fungus of the genus CANDIDA. It is usually a superficial infection of the moist areas of the body and is generally caused by CANDIDA ALBICANS. (Dorland, 27th ed)	2.41	2	0
Endometritis Inflammation of the ENDOMETRIUM, usually caused by intrauterine infections. Endometritis is the most common cause of postpartum fever.	2.01	1	0
Toxocariasis Infection by round worms of the genus TOXOCARA, usually found in wild and domesticated cats and dogs and foxes, except for the larvae, which may produce visceral and ocular larva migrans in man.	3.39	1	1
Trichocephaliasis [description not available]	3.39	1	1
Trichuriasis Infection with nematodes of the genus TRICHURIS, formerly called Trichocephalus.	3.39	1	1
Disease Exacerbation [description not available]	2.01	1	0
Ape Diseases Diseases of chimpanzees, gorillas, and orangutans.	2.01	1	0
Body Weight The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.	2.02	1	0
Parasite Infections [description not available]	1.98	1	0
Maggot Infestations [description not available]	1.99	1	0
Coccidioides immitis Infection [description not available]	2	1	0
Coccidioidomycosis Infection with a fungus of the genus COCCIDIOIDES, endemic to the SOUTHWESTERN UNITED STATES. It is sometimes called valley fever but should not be confused with RIFT VALLEY FEVER. Infection is caused by inhalation of airborne, fungal particles known as arthroconidia, a form of FUNGAL SPORES. A primary form is an acute, benign, self-limited respiratory infection. A secondary form is a virulent, severe, chronic, progressive granulomatous disease with systemic involvement. It can be detected by use of COCCIDIOIDIN.	2	1	0
Tick Paralysis Paralysis caused by a neurotropic toxin secreted by the salivary glands of ticks.	2	1	0
Alopecia Cicatrisata [description not available]	2	1	0
Alopecia Absence of hair from areas where it is normally present.	2	1	0
Adverse Drug Event [description not available]	2.92	1	0
Drug-Related Side Effects and Adverse Reactions Disorders that result from the intended use of PHARMACEUTICAL PREPARATIONS. Included in this heading are a broad variety of chemically-induced adverse conditions due to toxicity, DRUG INTERACTIONS, and metabolic effects of pharmaceuticals.	2.92	1	0

fluphenacur

Description

Cross-References

Synonyms (122)

Research Excerpts

Toxicity

Compound-Compound Interactions

Bioavailability

Dosage Studied

Drug Classes (5)

Protein Targets (30)

Potency Measurements

Biological Processes (82)

Molecular Functions (31)

Ceullar Components (30)

Bioassays (215)

Research

Studies (140)

Market Indicators

Research Demand Index: 9.63

Study Types

fluphenacur

Description

Cross-References

Synonyms (122)

Research Excerpts

Toxicity

Compound-Compound Interactions

Bioavailability

Dosage Studied

Drug Classes (5)

Protein Targets (30)

Potency Measurements

Biological Processes (82)

Molecular Functions (31)

Ceullar Components (30)

Bioassays (215)

Research

Studies (140)

Market Indicators

Research Demand Index: 9.63

Study Types

Related Drugs (69)

Related Conditions (46)