| Assay ID | Title | Year | Journal | Article |
|---|
| AID219416 | Cytotoxicity in human embryonic lung flbroblast Wl-38 cells using WST-1 viability assay | 1999 | Bioorganic & medicinal chemistry letters, Feb-22, Volume: 9, Issue:4
| Nonpeptide small-molecular inhibitors of dipeptidyl peptidase IV: N-phenylphthalimide analogs. |
| AID218281 | The cytotoxicity of the compounds assessed using human embryonic lung fibroblast WI-38 cells at (39 micro M) | 1997 | Journal of medicinal chemistry, Aug-29, Volume: 40, Issue:18
| Novel biological response modifiers: phthalimides with tumor necrosis factor-alpha production-regulating activity. |
| AID56211 | Inhibitory activity against dipeptidyl peptidase IV (DPP- IV) | 1998 | Journal of medicinal chemistry, Jan-29, Volume: 41, Issue:3
| Novel potent nonpeptide aminopeptidase N inhibitors with a cyclic imide skeleton. |
| AID38364 | Inhibitory activity against aminopeptidase N (APN) in human acute lymphoblastic leukemia MOLT-4 cell line | 1999 | Bioorganic & medicinal chemistry letters, Feb-22, Volume: 9, Issue:4
| Nonpeptide small-molecular inhibitors of dipeptidyl peptidase IV: N-phenylphthalimide analogs. |
| AID252631 | NBT positivity against human leukemia cell line HL-60 at 3*E-6 M | 2005 | Bioorganic & medicinal chemistry letters, Jul-01, Volume: 15, Issue:13
| Cell differentiation inducers derived from thalidomide. |
| AID251888 | Cell growth-inhibitory activity toward human leukemia cell line HL60 at 6 uM concentration | 2005 | Bioorganic & medicinal chemistry letters, Jan-17, Volume: 15, Issue:2
| Tubulin-polymerization inhibitors derived from thalidomide. |
| AID252971 | Percent cell proliferation of human leukemia cell line HL-60 at 1*E-6 M | 2005 | Bioorganic & medicinal chemistry letters, Jul-01, Volume: 15, Issue:13
| Cell differentiation inducers derived from thalidomide. |
| AID251661 | Inhibitory activity against tubulin polymerization at 20 uM | 2005 | Bioorganic & medicinal chemistry letters, Jan-17, Volume: 15, Issue:2
| Tubulin-polymerization inhibitors derived from thalidomide. |
| AID252974 | Percent cell proliferation of human leukemia cell line HL-60 at 3*E-6 M | 2005 | Bioorganic & medicinal chemistry letters, Jul-01, Volume: 15, Issue:13
| Cell differentiation inducers derived from thalidomide. |
| AID251886 | Cell growth-inhibitory activity toward human leukemia cell line HL60 at 10 uM concentration | 2005 | Bioorganic & medicinal chemistry letters, Jan-17, Volume: 15, Issue:2
| Tubulin-polymerization inhibitors derived from thalidomide. |
| AID81272 | Tumor necrosis factor-alpha production in human leukemia cell line (HL-60) stimulated with 50 nM okadaic acid (OA), at 30 uMolar. | 1997 | Journal of medicinal chemistry, Aug-29, Volume: 40, Issue:18
| Novel biological response modifiers: phthalimides with tumor necrosis factor-alpha production-regulating activity. |
| AID56226 | Inhibitory activity against Dipeptidylpeptidase IV (DPP IV) in human acute lymphoblastic leukemia MOLT-4 cell line | 1999 | Bioorganic & medicinal chemistry letters, Feb-22, Volume: 9, Issue:4
| Nonpeptide small-molecular inhibitors of dipeptidyl peptidase IV: N-phenylphthalimide analogs. |
| AID448438 | Inhibition of NF-kappaB activation | 2009 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 19, Issue:19
| The first pharmacophore model for potent NF-kappaB inhibitors. |
| AID1057528 | Induction of purified porcine brain tubulin polymerization assessed as microtubule-stabilization at 50 uM by spectrophotometric analysis | 2013 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 23, Issue:24
| Structure-activity relationship studies of thalidomide analogs with a taxol-like mode of action. |
| AID1057529 | Induction of purified porcine brain tubulin polymerization at 50 uM by spectrophotometric analysis | 2013 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 23, Issue:24
| Structure-activity relationship studies of thalidomide analogs with a taxol-like mode of action. |
| AID257636 | Inhibitory activity in HUVEC tube formation assay at 100 uM | 2005 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 15, Issue:24
| Angiogenesis inhibitors derived from thalidomide. |
| AID1057532 | Antiproliferative activity against human PC3 cells assessed as growth inhibition by MTS assay | 2013 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 23, Issue:24
| Structure-activity relationship studies of thalidomide analogs with a taxol-like mode of action. |
| AID309667 | Inhibition of IL-1-alpha-induced NF-kappaB activation in HeLa cells assessed as blocking of p50/p65 nuclear translocation | 2007 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 17, Issue:21
| Inhibitors of NF-kappaB derived from thalidomide. |
| AID1057531 | Antiproliferative activity against human DU145 cells assessed as growth inhibition by MTS assay | 2013 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 23, Issue:24
| Structure-activity relationship studies of thalidomide analogs with a taxol-like mode of action. |
| AID252632 | NBT positivity against human leukemia cell line HL-60 at 5*E-6 M | 2005 | Bioorganic & medicinal chemistry letters, Jul-01, Volume: 15, Issue:13
| Cell differentiation inducers derived from thalidomide. |
| AID252975 | Percent cell proliferation of human leukemia cell line HL-60 at 5*E-6 M | 2005 | Bioorganic & medicinal chemistry letters, Jul-01, Volume: 15, Issue:13
| Cell differentiation inducers derived from thalidomide. |
| AID270728 | Inhibition of tubulin polymerization in porcine brain | 2006 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 16, Issue:18
| Tubulin polymerization inhibitors with a fluorinated phthalimide skeleton derived from thalidomide. |
| AID38377 | Inhibitory activity against aminopeptidase N assayed by the L-Ala-MCA method. | 1998 | Journal of medicinal chemistry, Jan-29, Volume: 41, Issue:3
| Novel potent nonpeptide aminopeptidase N inhibitors with a cyclic imide skeleton. |
| AID252628 | NBT positivity against human leukemia cell line HL-60 at 1*E-6 M | 2005 | Bioorganic & medicinal chemistry letters, Jul-01, Volume: 15, Issue:13
| Cell differentiation inducers derived from thalidomide. |
| AID81275 | Tumor necrosis factor-alpha production in human leukemia cell line (HL-60) stimulated with 10 nM 12-O-tetradecanoylphorbol 13-acetate (TPA) at 30 uMolar. | 1997 | Journal of medicinal chemistry, Aug-29, Volume: 40, Issue:18
| Novel biological response modifiers: phthalimides with tumor necrosis factor-alpha production-regulating activity. |
| AID1057530 | Antiproliferative activity against human MDA-MB-231 cells assessed as growth inhibition by MTS assay | 2013 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 23, Issue:24
| Structure-activity relationship studies of thalidomide analogs with a taxol-like mode of action. |
| AID251887 | Cell growth-inhibitory activity toward human leukemia cell line HL60 at 3 uM concentration | 2005 | Bioorganic & medicinal chemistry letters, Jan-17, Volume: 15, Issue:2
| Tubulin-polymerization inhibitors derived from thalidomide. |
| AID1182019 | Induction of microtubule stabilization in human QBI293 cells assessed as increase in acetylated alpha-tubulin at 1 uM after 4 hrs by ELISA relative to vehicle treated control | 2014 | Journal of medicinal chemistry, Jul-24, Volume: 57, Issue:14
| Brain-penetrant, orally bioavailable microtubule-stabilizing small molecules are potential candidate therapeutics for Alzheimer's disease and related tauopathies. |
| AID257637 | Inhibitory activity in HUVEC tube formation assay at 30 uM | 2005 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 15, Issue:24
| Angiogenesis inhibitors derived from thalidomide. |
| AID257638 | Inhibitory activity in HUVEC tube formation assay at 10 uM | 2005 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 15, Issue:24
| Angiogenesis inhibitors derived from thalidomide. |
| AID1057533 | Antiproliferative activity against human PC3 cells assessed as growth inhibition at 30 uM by MTS assay | 2013 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 23, Issue:24
| Structure-activity relationship studies of thalidomide analogs with a taxol-like mode of action. |
| AID1347410 | qHTS for inhibitors of adenylyl cyclases using a fission yeast platform: a pilot screen against the NCATS LOPAC library | 2019 | Cellular signalling, 08, Volume: 60 | A fission yeast platform for heterologous expression of mammalian adenylyl cyclases and high throughput screening. |
| AID1347058 | CD47-SIRPalpha protein protein interaction - HTRF assay qHTS validation | 2019 | PloS one, , Volume: 14, Issue:7
| Quantitative high-throughput screening assays for the discovery and development of SIRPα-CD47 interaction inhibitors. |
| AID1347405 | qHTS to identify inhibitors of the type 1 interferon - major histocompatibility complex class I in skeletal muscle: primary screen against the NCATS LOPAC collection | 2020 | ACS chemical biology, 07-17, Volume: 15, Issue:7
| High-Throughput Screening to Identify Inhibitors of the Type I Interferon-Major Histocompatibility Complex Class I Pathway in Skeletal Muscle. |
| AID1347057 | CD47-SIRPalpha protein protein interaction - LANCE assay qHTS validation | 2019 | PloS one, , Volume: 14, Issue:7
| Quantitative high-throughput screening assays for the discovery and development of SIRPα-CD47 interaction inhibitors. |
| AID1347151 | Optimization of GU AMC qHTS for Zika virus inhibitors: Unlinked NS2B-NS3 protease assay | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1347059 | CD47-SIRPalpha protein protein interaction - Alpha assay qHTS validation | 2019 | PloS one, , Volume: 14, Issue:7
| Quantitative high-throughput screening assays for the discovery and development of SIRPα-CD47 interaction inhibitors. |
| AID1794808 | Fluorescence-based screening to identify small molecule inhibitors of Plasmodium falciparum apicoplast DNA polymerase (Pf-apPOL). | 2014 | Journal of biomolecular screening, Jul, Volume: 19, Issue:6
| A High-Throughput Assay to Identify Inhibitors of the Apicoplast DNA Polymerase from Plasmodium falciparum. |
| AID1794808 | Fluorescence-based screening to identify small molecule inhibitors of Plasmodium falciparum apicoplast DNA polymerase (Pf-apPOL). | | | |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |