| Assay ID | Title | Year | Journal | Article |
|---|
| AID1138475 | Cell cycle arrest in human A549 cells assessed as accumulation at G0/G1 phase at 10 uM after 24 hrs using propidium iodide staining by flow cytometry analysis (Rvb = 51 +/- 1.1%) | 2014 | Journal of natural products, Apr-25, Volume: 77, Issue:4
| Cephalochromin induces G0/G1 cell cycle arrest and apoptosis in A549 human non-small-cell lung cancer cells by inflicting mitochondrial disruption. |
| AID1138498 | Induction of apoptosis in human A549 cells assessed as induction of ROS production at 3 uM after 12 hrs using DCF-DA staining by flow cytometry analysis relative to control | 2014 | Journal of natural products, Apr-25, Volume: 77, Issue:4
| Cephalochromin induces G0/G1 cell cycle arrest and apoptosis in A549 human non-small-cell lung cancer cells by inflicting mitochondrial disruption. |
| AID1138472 | Cell cycle arrest in human A549 cells assessed as accumulation at sub-G1 phase at 10 uM after 24 hrs using propidium iodide staining by flow cytometry analysis (Rvb = 2 +/- 0.3%) | 2014 | Journal of natural products, Apr-25, Volume: 77, Issue:4
| Cephalochromin induces G0/G1 cell cycle arrest and apoptosis in A549 human non-small-cell lung cancer cells by inflicting mitochondrial disruption. |
| AID1138465 | Cytotoxicity against human A549 cells after 48 hrs by SRB assay | 2014 | Journal of natural products, Apr-25, Volume: 77, Issue:4
| Cephalochromin induces G0/G1 cell cycle arrest and apoptosis in A549 human non-small-cell lung cancer cells by inflicting mitochondrial disruption. |
| AID1138479 | Cell cycle arrest in human A549 cells assessed as accumulation at S phase at 10 uM after 36 hrs using propidium iodide staining by flow cytometry analysis (Rvb = 9.6 +/- 0.9%) | 2014 | Journal of natural products, Apr-25, Volume: 77, Issue:4
| Cephalochromin induces G0/G1 cell cycle arrest and apoptosis in A549 human non-small-cell lung cancer cells by inflicting mitochondrial disruption. |
| AID1138499 | Induction of apoptosis in human A549 cells assessed as induction of ROS production at 10 uM after 12 hrs using DCF-DA staining by flow cytometry analysis relative to control | 2014 | Journal of natural products, Apr-25, Volume: 77, Issue:4
| Cephalochromin induces G0/G1 cell cycle arrest and apoptosis in A549 human non-small-cell lung cancer cells by inflicting mitochondrial disruption. |
| AID1138489 | Induction of apoptosis in human A549 cells assessed as induction of cleaved PARP protein expression at 10 uM after 26 to 36 hrs by Western blot analysis | 2014 | Journal of natural products, Apr-25, Volume: 77, Issue:4
| Cephalochromin induces G0/G1 cell cycle arrest and apoptosis in A549 human non-small-cell lung cancer cells by inflicting mitochondrial disruption. |
| AID1138480 | Cell cycle arrest in human A549 cells assessed as accumulation at S phase at 10 uM after 48 hrs using propidium iodide staining by flow cytometry analysis (Rvb = 9.5 +/- 0.7%) | 2014 | Journal of natural products, Apr-25, Volume: 77, Issue:4
| Cephalochromin induces G0/G1 cell cycle arrest and apoptosis in A549 human non-small-cell lung cancer cells by inflicting mitochondrial disruption. |
| AID1138471 | Cytotoxicity against human SW1353 cells after 48 hrs by MTT assay | 2014 | Journal of natural products, Apr-25, Volume: 77, Issue:4
| Cephalochromin induces G0/G1 cell cycle arrest and apoptosis in A549 human non-small-cell lung cancer cells by inflicting mitochondrial disruption. |
| AID1138484 | Induction of apoptosis in human A549 cells assessed as DNA level after 24 to 48 hrs using propidium iodide staining by flow cytometry analysis | 2014 | Journal of natural products, Apr-25, Volume: 77, Issue:4
| Cephalochromin induces G0/G1 cell cycle arrest and apoptosis in A549 human non-small-cell lung cancer cells by inflicting mitochondrial disruption. |
| AID1138503 | Induction of apoptosis in human A549 cells assessed as induction of ROS production at 10 uM after 5 hrs using DCF-DA staining by flow cytometry analysis in presence of Tiron | 2014 | Journal of natural products, Apr-25, Volume: 77, Issue:4
| Cephalochromin induces G0/G1 cell cycle arrest and apoptosis in A549 human non-small-cell lung cancer cells by inflicting mitochondrial disruption. |
| AID1138477 | Cell cycle arrest in human A549 cells assessed as accumulation at G0/G1 phase at 10 uM after 48 hrs using propidium iodide staining by flow cytometry analysis (Rvb = 57.3 +/- 0.9%) | 2014 | Journal of natural products, Apr-25, Volume: 77, Issue:4
| Cephalochromin induces G0/G1 cell cycle arrest and apoptosis in A549 human non-small-cell lung cancer cells by inflicting mitochondrial disruption. |
| AID1138466 | Cytotoxicity against human A549 cells after 48 hrs by MTT assay | 2014 | Journal of natural products, Apr-25, Volume: 77, Issue:4
| Cephalochromin induces G0/G1 cell cycle arrest and apoptosis in A549 human non-small-cell lung cancer cells by inflicting mitochondrial disruption. |
| AID1138467 | Cytotoxicity against human Hep3B cells after 48 hrs by MTT assay | 2014 | Journal of natural products, Apr-25, Volume: 77, Issue:4
| Cephalochromin induces G0/G1 cell cycle arrest and apoptosis in A549 human non-small-cell lung cancer cells by inflicting mitochondrial disruption. |
| AID673913 | Inhibition of Clostridium botulinum Hall BoNT/A protease activity using Ac-SNKTRIDEANQRATKML-NH2 as substrate at 20 uM after 5 mins by RP-HPLC analysis | 2012 | ACS medicinal chemistry letters, May-10, Volume: 3, Issue:5
| Fungal bis-Naphthopyrones as Inhibitors of Botulinum Neurotoxin Serotype A. |
| AID1138478 | Cell cycle arrest in human A549 cells assessed as accumulation at S phase at 10 uM after 24 hrs using propidium iodide staining by flow cytometry analysis (Rvb = 12 +/- 1.4%) | 2014 | Journal of natural products, Apr-25, Volume: 77, Issue:4
| Cephalochromin induces G0/G1 cell cycle arrest and apoptosis in A549 human non-small-cell lung cancer cells by inflicting mitochondrial disruption. |
| AID1138470 | Cytotoxicity against human HuH7 cells after 48 hrs by MTT assay | 2014 | Journal of natural products, Apr-25, Volume: 77, Issue:4
| Cephalochromin induces G0/G1 cell cycle arrest and apoptosis in A549 human non-small-cell lung cancer cells by inflicting mitochondrial disruption. |
| AID1138488 | Induction of apoptosis in human A549 cells assessed as proteolytic cleavage of inactive procaspase-8, 9, and 3 into active caspase-8, 9, and 3 at 10 uM by Western blot analysis | 2014 | Journal of natural products, Apr-25, Volume: 77, Issue:4
| Cephalochromin induces G0/G1 cell cycle arrest and apoptosis in A549 human non-small-cell lung cancer cells by inflicting mitochondrial disruption. |
| AID1138504 | Induction of apoptosis in human A549 cells assessed as increase in expression of LC3-II at 10 uM by Western blot analysis | 2014 | Journal of natural products, Apr-25, Volume: 77, Issue:4
| Cephalochromin induces G0/G1 cell cycle arrest and apoptosis in A549 human non-small-cell lung cancer cells by inflicting mitochondrial disruption. |
| AID1138490 | Induction of apoptosis in human A549 cells assessed as reduction of survivin expression at 10 uM by Western blot analysis | 2014 | Journal of natural products, Apr-25, Volume: 77, Issue:4
| Cephalochromin induces G0/G1 cell cycle arrest and apoptosis in A549 human non-small-cell lung cancer cells by inflicting mitochondrial disruption. |
| AID1138493 | Induction of apoptosis in human A549 cells assessed as hypodiploid DNA content at 10 to 20 uM after 48 hrs by flow cytometry analysis in presence of Z-VAD-fmk | 2014 | Journal of natural products, Apr-25, Volume: 77, Issue:4
| Cephalochromin induces G0/G1 cell cycle arrest and apoptosis in A549 human non-small-cell lung cancer cells by inflicting mitochondrial disruption. |
| AID1138487 | Induction of apoptosis in human A549 cells assessed as downregulation of cyclin D1, cyclin E, Cdk 2, and Cdk 4 protein levels after 24 hrs by Western blot analysis | 2014 | Journal of natural products, Apr-25, Volume: 77, Issue:4
| Cephalochromin induces G0/G1 cell cycle arrest and apoptosis in A549 human non-small-cell lung cancer cells by inflicting mitochondrial disruption. |
| AID333259 | Antagonist activity at human glucagon receptor expressed in BHK21 cells assessed as inhibition of glucagon-induced cAMP elevation by RIA | 2004 | Journal of natural products, Sep, Volume: 67, Issue:9
| BI-32169, a bicyclic 19-peptide with strong glucagon receptor antagonist activity from Streptomyces sp. |
| AID1138486 | Induction of apoptosis in human A549 cells assessed as downregulation of cyclin D1, cyclin E, Cdk 2, and Cdk 4 protein levels at 10 uM after 6 to 36 hrs by Western blot analysis | 2014 | Journal of natural products, Apr-25, Volume: 77, Issue:4
| Cephalochromin induces G0/G1 cell cycle arrest and apoptosis in A549 human non-small-cell lung cancer cells by inflicting mitochondrial disruption. |
| AID1138496 | Induction of apoptosis in human A549 cells assessed as induction of ROS production after 12 hrs using DCF-DA staining by flow cytometry analysis | 2014 | Journal of natural products, Apr-25, Volume: 77, Issue:4
| Cephalochromin induces G0/G1 cell cycle arrest and apoptosis in A549 human non-small-cell lung cancer cells by inflicting mitochondrial disruption. |
| AID1138502 | Induction of apoptosis in human A549 cells assessed as induction of ROS production at 10 uM using DCF-DA staining by flow cytometry analysis relative to control | 2014 | Journal of natural products, Apr-25, Volume: 77, Issue:4
| Cephalochromin induces G0/G1 cell cycle arrest and apoptosis in A549 human non-small-cell lung cancer cells by inflicting mitochondrial disruption. |
| AID1138494 | Induction of apoptosis in human A549 cells assessed as loss of mitochondrial membrane potential at 10 to 30 uM after 12 to 24 hrs by flow cytometry analysis | 2014 | Journal of natural products, Apr-25, Volume: 77, Issue:4
| Cephalochromin induces G0/G1 cell cycle arrest and apoptosis in A549 human non-small-cell lung cancer cells by inflicting mitochondrial disruption. |
| AID1138501 | Induction of apoptosis in human A549 cells assessed as induction of ROS production at 5 mM after 12 hrs using DCF-DA staining by flow cytometry analysis relative to control | 2014 | Journal of natural products, Apr-25, Volume: 77, Issue:4
| Cephalochromin induces G0/G1 cell cycle arrest and apoptosis in A549 human non-small-cell lung cancer cells by inflicting mitochondrial disruption. |
| AID1138483 | Cell cycle arrest in human A549 cells assessed as accumulation at G2/M phase at 10 uM after 48 hrs using propidium iodide staining by flow cytometry analysis (Rvb = 31.9 +/- 1.4%) | 2014 | Journal of natural products, Apr-25, Volume: 77, Issue:4
| Cephalochromin induces G0/G1 cell cycle arrest and apoptosis in A549 human non-small-cell lung cancer cells by inflicting mitochondrial disruption. |
| AID673915 | Inhibition of Clostridium botulinum Hall BoNT/A-mediated paralysis in CD1 mouse phrenic nerve hemidiaphragm assessed as time required to 50% loss of twitch tension at 20 uM measured upto 5 hrs (Rvb = 62 mins) | 2012 | ACS medicinal chemistry letters, May-10, Volume: 3, Issue:5
| Fungal bis-Naphthopyrones as Inhibitors of Botulinum Neurotoxin Serotype A. |
| AID673912 | Inhibition of Clostridium botulinum Hall BoNT/A protease activity using Ac-SNKTRIDEANQRATKML-NH2 as substrate at 100 uM after 5 mins by RP-HPLC analysis | 2012 | ACS medicinal chemistry letters, May-10, Volume: 3, Issue:5
| Fungal bis-Naphthopyrones as Inhibitors of Botulinum Neurotoxin Serotype A. |
| AID1138481 | Cell cycle arrest in human A549 cells assessed as accumulation at G2/M phase at 10 uM after 24 hrs using propidium iodide staining by flow cytometry analysis (Rvb = 35.2 +/- 2.3%) | 2014 | Journal of natural products, Apr-25, Volume: 77, Issue:4
| Cephalochromin induces G0/G1 cell cycle arrest and apoptosis in A549 human non-small-cell lung cancer cells by inflicting mitochondrial disruption. |
| AID1138476 | Cell cycle arrest in human A549 cells assessed as accumulation at G0/G1 phase at 10 uM after 36 hrs using propidium iodide staining by flow cytometry analysis (Rvb = 53.1 +/- 1.2%) | 2014 | Journal of natural products, Apr-25, Volume: 77, Issue:4
| Cephalochromin induces G0/G1 cell cycle arrest and apoptosis in A549 human non-small-cell lung cancer cells by inflicting mitochondrial disruption. |
| AID1138469 | Cytotoxicity against human HT1080 cells after 48 hrs by MTT assay | 2014 | Journal of natural products, Apr-25, Volume: 77, Issue:4
| Cephalochromin induces G0/G1 cell cycle arrest and apoptosis in A549 human non-small-cell lung cancer cells by inflicting mitochondrial disruption. |
| AID1138468 | Cytotoxicity against human Caco2 cells after 48 hrs by MTT assay | 2014 | Journal of natural products, Apr-25, Volume: 77, Issue:4
| Cephalochromin induces G0/G1 cell cycle arrest and apoptosis in A549 human non-small-cell lung cancer cells by inflicting mitochondrial disruption. |
| AID1138474 | Cell cycle arrest in human A549 cells assessed as accumulation at sub-G1 phase at 10 uM after 48 hrs using propidium iodide staining by flow cytometry analysis (Rvb = 1.5 +/- 0.1%) | 2014 | Journal of natural products, Apr-25, Volume: 77, Issue:4
| Cephalochromin induces G0/G1 cell cycle arrest and apoptosis in A549 human non-small-cell lung cancer cells by inflicting mitochondrial disruption. |
| AID1138492 | Induction of apoptosis in human A549 cells assessed as reduction of Bad proteins expression at 10 uM after 6 to 36 hrs by Western blot analysis | 2014 | Journal of natural products, Apr-25, Volume: 77, Issue:4
| Cephalochromin induces G0/G1 cell cycle arrest and apoptosis in A549 human non-small-cell lung cancer cells by inflicting mitochondrial disruption. |
| AID1138473 | Cell cycle arrest in human A549 cells assessed as accumulation at sub-G1 phase at 10 uM after 36 hrs using propidium iodide staining by flow cytometry analysis (Rvb = 1.7 +/- 0.4%) | 2014 | Journal of natural products, Apr-25, Volume: 77, Issue:4
| Cephalochromin induces G0/G1 cell cycle arrest and apoptosis in A549 human non-small-cell lung cancer cells by inflicting mitochondrial disruption. |
| AID1138500 | Induction of apoptosis in human A549 cells assessed as induction of ROS production at 30 uM after 12 hrs using DCF-DA staining by flow cytometry analysis relative to control | 2014 | Journal of natural products, Apr-25, Volume: 77, Issue:4
| Cephalochromin induces G0/G1 cell cycle arrest and apoptosis in A549 human non-small-cell lung cancer cells by inflicting mitochondrial disruption. |
| AID673914 | Inhibition of Clostridium botulinum Hall BoNT/A protease activity using Ac-SNKTRIDEANQRATKML-NH2 as substrate after 5 mins by RP-HPLC analysis | 2012 | ACS medicinal chemistry letters, May-10, Volume: 3, Issue:5
| Fungal bis-Naphthopyrones as Inhibitors of Botulinum Neurotoxin Serotype A. |
| AID1138497 | Induction of apoptosis in human A549 cells assessed as induction of ROS production at 1 uM after 12 hrs using DCF-DA staining by flow cytometry analysis relative to control | 2014 | Journal of natural products, Apr-25, Volume: 77, Issue:4
| Cephalochromin induces G0/G1 cell cycle arrest and apoptosis in A549 human non-small-cell lung cancer cells by inflicting mitochondrial disruption. |
| AID673916 | Inhibition of Clostridium botulinum Hall BoNT/A-mediated paralysis in CD1 mouse phrenic nerve hemidiaphragm assessed as time required to 50% loss of twitch tension at 2 uM measured upto 5 hrs (Rvb = 62 mins) | 2012 | ACS medicinal chemistry letters, May-10, Volume: 3, Issue:5
| Fungal bis-Naphthopyrones as Inhibitors of Botulinum Neurotoxin Serotype A. |
| AID1138491 | Induction of apoptosis in human A549 cells assessed as reduction of Bcl-xL expression at 10 uM after 6 to 36 hrs by Western blot analysis | 2014 | Journal of natural products, Apr-25, Volume: 77, Issue:4
| Cephalochromin induces G0/G1 cell cycle arrest and apoptosis in A549 human non-small-cell lung cancer cells by inflicting mitochondrial disruption. |
| AID1138482 | Cell cycle arrest in human A549 cells assessed as accumulation at G2/M phase at 10 uM after 36 hrs using propidium iodide staining by flow cytometry analysis (Rvb = 35.8 +/- 1.8%) | 2014 | Journal of natural products, Apr-25, Volume: 77, Issue:4
| Cephalochromin induces G0/G1 cell cycle arrest and apoptosis in A549 human non-small-cell lung cancer cells by inflicting mitochondrial disruption. |
| AID1138485 | Induction of apoptosis in human A549 cells assessed as DNA level at 3 to 30 uM using propidium iodide staining by flow cytometry analysis | 2014 | Journal of natural products, Apr-25, Volume: 77, Issue:4
| Cephalochromin induces G0/G1 cell cycle arrest and apoptosis in A549 human non-small-cell lung cancer cells by inflicting mitochondrial disruption. |
| AID1138495 | Induction of apoptosis in human A549 cells assessed as loss of mitochondrial membrane potential at 50 uM after 12 to 24 hrs by flow cytometry analysis | 2014 | Journal of natural products, Apr-25, Volume: 77, Issue:4
| Cephalochromin induces G0/G1 cell cycle arrest and apoptosis in A549 human non-small-cell lung cancer cells by inflicting mitochondrial disruption. |
| AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1
| High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID504812 | Inverse Agonists of the Thyroid Stimulating Hormone Receptor: HTS campaign | 2010 | Endocrinology, Jul, Volume: 151, Issue:7
| A small molecule inverse agonist for the human thyroid-stimulating hormone receptor. |
| AID504810 | Antagonists of the Thyroid Stimulating Hormone Receptor: HTS campaign | 2010 | Endocrinology, Jul, Volume: 151, Issue:7
| A small molecule inverse agonist for the human thyroid-stimulating hormone receptor. |
| AID651635 | Viability Counterscreen for Primary qHTS for Inhibitors of ATXN expression | | | |
| AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1
| High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1
| High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID1745845 | Primary qHTS for Inhibitors of ATXN expression | | | |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |