Compounds > sr 3335
Page last updated: 2024-09-28

sr 3335

Description

SR 3335: a retinoic acid receptor-related receptor alpha (RORalpha) inverse agonist; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID2360837
CHEMBL ID3218916
CHEBI ID92371
SCHEMBL ID12334063
MeSH IDM0561908

Synonyms (41)

Synonym
ml176
SR-06000113335-2
n-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]thiophene-2-sulfonamide
smr001835204
n-{4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl}thiophene-2-sulfonamide
MLS003126319
HY-14413
sr3335
CS-1044
S2969
CHEMBL3218916
293753-05-6
n-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)thiophene-2-sulfonamide
SCHEMBL12334063
AC-32811
AKOS030526772
DTXSID70368245
n-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxy-2-propanyl)phenyl]-2-thiophenesulfonamide
CHEBI:92371
AS-74314
NCGC00378899-03
lzwunzrmanfrao-uhfffaoysa-n
sr-3335
Q27164113
n-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-2-thiophenesulfonamide
n-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-2-thiophenesulfonamide
2-thiophenesulfonamide, n-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-
HMS3740K07
ml 176
BCP13177
sr-3335;sr 3335; ml 176; ml-176; ml176
thiophene-2-sulfonic acid [4-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethyl-ethyl)-phenyl]-amide
A858110
C74505
NCGC00378899-02
EX-A5630
2-thiophenesulfonamide, n-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-?
sr 3335
mfcd02724814
EN300-7384569
Z56820858

Drug Classes (1)

ClassDescription
sulfonamideAn amide of a sulfonic acid RS(=O)2NR'2.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Protein Targets (11)

Potency Measurements

ProteinTaxonomyMeasurementAverage (µ)Min (ref.)Avg (ref.)Max (ref.)Bioassay(s)
cytochrome P450 family 3 subfamily A polypeptide 4Homo sapiens (human)Potency7.56370.01237.983543.2770AID1645841
GVesicular stomatitis virusPotency1.89990.01238.964839.8107AID1645842
cytochrome P450 2D6Homo sapiens (human)Potency21.31740.00108.379861.1304AID1645840
Interferon betaHomo sapiens (human)Potency1.89990.00339.158239.8107AID1645842
HLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)Potency1.89990.01238.964839.8107AID1645842
Inositol hexakisphosphate kinase 1Homo sapiens (human)Potency1.89990.01238.964839.8107AID1645842
cytochrome P450 2C9, partialHomo sapiens (human)Potency1.89990.01238.964839.8107AID1645842
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Inhibition Measurements

ProteinTaxonomyMeasurementAverageMin (ref.)Avg (ref.)Max (ref.)Bioassay(s)
glucose-6-phosphatase isoform 1Homo sapiens (human)IC50 (µMol)1.40001.40001.40001.4000AID463172
nuclear receptor ROR-alpha isoform aHomo sapiens (human)IC50 (µMol)0.48000.48000.48000.4800AID463152
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Activation Measurements

ProteinTaxonomyMeasurementAverageMin (ref.)Avg (ref.)Max (ref.)Bioassay(s)
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Biological Processes (45)

Processvia Protein(s)Taxonomy
cell surface receptor signaling pathway via JAK-STATInterferon betaHomo sapiens (human)
response to exogenous dsRNAInterferon betaHomo sapiens (human)
B cell activation involved in immune responseInterferon betaHomo sapiens (human)
cell surface receptor signaling pathwayInterferon betaHomo sapiens (human)
cell surface receptor signaling pathway via JAK-STATInterferon betaHomo sapiens (human)
response to virusInterferon betaHomo sapiens (human)
positive regulation of autophagyInterferon betaHomo sapiens (human)
cytokine-mediated signaling pathwayInterferon betaHomo sapiens (human)
natural killer cell activationInterferon betaHomo sapiens (human)
positive regulation of peptidyl-serine phosphorylation of STAT proteinInterferon betaHomo sapiens (human)
cellular response to interferon-betaInterferon betaHomo sapiens (human)
B cell proliferationInterferon betaHomo sapiens (human)
negative regulation of viral genome replicationInterferon betaHomo sapiens (human)
innate immune responseInterferon betaHomo sapiens (human)
positive regulation of innate immune responseInterferon betaHomo sapiens (human)
regulation of MHC class I biosynthetic processInterferon betaHomo sapiens (human)
negative regulation of T cell differentiationInterferon betaHomo sapiens (human)
positive regulation of transcription by RNA polymerase IIInterferon betaHomo sapiens (human)
defense response to virusInterferon betaHomo sapiens (human)
type I interferon-mediated signaling pathwayInterferon betaHomo sapiens (human)
neuron cellular homeostasisInterferon betaHomo sapiens (human)
cellular response to exogenous dsRNAInterferon betaHomo sapiens (human)
cellular response to virusInterferon betaHomo sapiens (human)
negative regulation of Lewy body formationInterferon betaHomo sapiens (human)
negative regulation of T-helper 2 cell cytokine productionInterferon betaHomo sapiens (human)
positive regulation of apoptotic signaling pathwayInterferon betaHomo sapiens (human)
response to exogenous dsRNAInterferon betaHomo sapiens (human)
B cell differentiationInterferon betaHomo sapiens (human)
natural killer cell activation involved in immune responseInterferon betaHomo sapiens (human)
adaptive immune responseInterferon betaHomo sapiens (human)
T cell activation involved in immune responseInterferon betaHomo sapiens (human)
humoral immune responseInterferon betaHomo sapiens (human)
positive regulation of T cell mediated cytotoxicityHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
adaptive immune responseHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independentHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
regulation of T cell anergyHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
defense responseHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
immune responseHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
detection of bacteriumHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
regulation of interleukin-12 productionHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
regulation of interleukin-6 productionHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
protection from natural killer cell mediated cytotoxicityHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
innate immune responseHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
regulation of dendritic cell differentiationHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
antigen processing and presentation of endogenous peptide antigen via MHC class IbHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
inositol phosphate metabolic processInositol hexakisphosphate kinase 1Homo sapiens (human)
phosphatidylinositol phosphate biosynthetic processInositol hexakisphosphate kinase 1Homo sapiens (human)
negative regulation of cold-induced thermogenesisInositol hexakisphosphate kinase 1Homo sapiens (human)
inositol phosphate biosynthetic processInositol hexakisphosphate kinase 1Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Molecular Functions (18)

Processvia Protein(s)Taxonomy
cytokine activityInterferon betaHomo sapiens (human)
cytokine receptor bindingInterferon betaHomo sapiens (human)
type I interferon receptor bindingInterferon betaHomo sapiens (human)
protein bindingInterferon betaHomo sapiens (human)
chloramphenicol O-acetyltransferase activityInterferon betaHomo sapiens (human)
TAP bindingHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
signaling receptor bindingHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
protein bindingHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
peptide antigen bindingHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
TAP bindingHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
protein-folding chaperone bindingHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
inositol-1,3,4,5,6-pentakisphosphate kinase activityInositol hexakisphosphate kinase 1Homo sapiens (human)
inositol hexakisphosphate kinase activityInositol hexakisphosphate kinase 1Homo sapiens (human)
inositol heptakisphosphate kinase activityInositol hexakisphosphate kinase 1Homo sapiens (human)
inositol hexakisphosphate 5-kinase activityInositol hexakisphosphate kinase 1Homo sapiens (human)
protein bindingInositol hexakisphosphate kinase 1Homo sapiens (human)
ATP bindingInositol hexakisphosphate kinase 1Homo sapiens (human)
inositol hexakisphosphate 1-kinase activityInositol hexakisphosphate kinase 1Homo sapiens (human)
inositol hexakisphosphate 3-kinase activityInositol hexakisphosphate kinase 1Homo sapiens (human)
inositol 5-diphosphate pentakisphosphate 5-kinase activityInositol hexakisphosphate kinase 1Homo sapiens (human)
inositol diphosphate tetrakisphosphate kinase activityInositol hexakisphosphate kinase 1Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Ceullar Components (22)

Processvia Protein(s)Taxonomy
extracellular spaceInterferon betaHomo sapiens (human)
extracellular regionInterferon betaHomo sapiens (human)
Golgi membraneHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
endoplasmic reticulumHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
Golgi apparatusHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
plasma membraneHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
cell surfaceHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
ER to Golgi transport vesicle membraneHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
membraneHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
secretory granule membraneHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
phagocytic vesicle membraneHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
early endosome membraneHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
recycling endosome membraneHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
extracellular exosomeHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
lumenal side of endoplasmic reticulum membraneHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
MHC class I protein complexHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
extracellular spaceHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
external side of plasma membraneHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
fibrillar centerInositol hexakisphosphate kinase 1Homo sapiens (human)
nucleoplasmInositol hexakisphosphate kinase 1Homo sapiens (human)
cytosolInositol hexakisphosphate kinase 1Homo sapiens (human)
nucleusInositol hexakisphosphate kinase 1Homo sapiens (human)
cytoplasmInositol hexakisphosphate kinase 1Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Bioassays (5)

Assay IDTitleYearJournalArticle
AID1347160Primary screen NINDS Rhodamine qHTS for Zika virus inhibitors2020Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
AID1296008Cytotoxic Profiling of Annotated Libraries Using Quantitative High-Throughput Screening2020SLAS discovery : advancing life sciences R & D, 01, Volume: 25, Issue:1
Cytotoxic Profiling of Annotated and Diverse Chemical Libraries Using Quantitative High-Throughput Screening.
AID1346987P-glycoprotein substrates identified in KB-8-5-11 adenocarcinoma cell line, qHTS therapeutic library screen2019Molecular pharmacology, 11, Volume: 96, Issue:5
A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
AID1347159Primary screen GU Rhodamine qHTS for Zika virus inhibitors: Unlinked NS2B-NS3 protease assay2020Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
AID1346986P-glycoprotein substrates identified in KB-3-1 adenocarcinoma cell line, qHTS therapeutic library screen2019Molecular pharmacology, 11, Volume: 96, Issue:5
A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (12)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (41.67)24.3611
2020's7 (58.33)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other12 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceDescriptionRelationhip StrengthStudiesTrialsClassesRoles
thiophenes[no description available]medium90mancude organic heteromonocyclic parent;
monocyclic heteroarene;
thiophenes;
volatile organic compound		non-polar solvent
sr 1078[no description available]medium30
thiazoles[no description available]medium101,3-thiazoles;
mancude organic heteromonocyclic parent;
monocyclic heteroarene
sr1001[no description available]medium10sulfonamide
wortmannin[no description available]medium10acetate ester;
cyclic ketone;
delta-lactone;
organic heteropentacyclic compound		anticoronaviral agent;
antineoplastic agent;
autophagy inhibitor;
EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor;
geroprotector;
Penicillium metabolite;
radiosensitizing agent
pyrroles[no description available]medium10pyrrole;
secondary amine
triciribine[no description available]medium10
nvp-aew541[no description available]medium10
formaldehyde[no description available]medium10aldehyde;
one-carbon compound		allergen;
carcinogenic agent;
disinfectant;
EC 3.5.1.4 (amidase) inhibitor;
environmental contaminant;
Escherichia coli metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
acetazolamide[no description available]low00monocarboxylic acid amide;
sulfonamide;
thiadiazoles		anticonvulsant;
diuretic;
EC 4.2.1.1 (carbonic anhydrase) inhibitor
1-(4-methanesulfonamidophenoxy)-3-(n-methyl-3,4-dichlorophenylethylamino)-2-propanol[no description available]low00sulfonamide
amosulalol[no description available]low00sulfonamide
ampiroxicam[no description available]low00acetal;
aminopyridine;
benzothiazine;
etabonate ester;
monocarboxylic acid amide;
sulfonamide		analgesic;
antirheumatic drug;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
non-steroidal anti-inflammatory drug;
prodrug
amsacrine[no description available]low00acridines;
aromatic ether;
sulfonamide		antineoplastic agent;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor
azosemide[no description available]low00monochlorobenzenes;
sulfonamide;
tetrazoles;
thiophenes		loop diuretic
bendroflumethiazide[no description available]low00benzothiadiazine;
sulfonamide		antihypertensive agent;
diuretic
benzothiazide[no description available]low00benzothiadiazine;
sulfonamide		antihypertensive agent;
diuretic
benzylhydrochlorothiazide[no description available]low00benzenes;
benzothiadiazine;
organochlorine compound;
secondary amino compound;
sulfonamide
bumetanide[no description available]low00amino acid;
benzoic acids;
sulfonamide		diuretic;
EC 3.6.3.49 (channel-conductance-controlling ATPase) inhibitor
celecoxib[no description available]low00organofluorine compound;
pyrazoles;
sulfonamide;
toluenes		cyclooxygenase 2 inhibitor;
geroprotector;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug
chlorthalidone[no description available]low00isoindoles;
monochlorobenzenes;
sulfonamide
4-chloro-N-(2,6-dimethyl-1-piperidinyl)-3-sulfamoylbenzamide[no description available]low00sulfonamide
dichlorphenamide[no description available]low00dichlorobenzene;
sulfonamide		antiglaucoma drug;
EC 4.2.1.1 (carbonic anhydrase) inhibitor;
ophthalmology drug
e 4031[no description available]low00sulfonamide
ethoxzolamide[no description available]low00aromatic ether;
benzothiazoles;
sulfonamide		antiglaucoma drug;
diuretic;
EC 4.2.1.1 (carbonic anhydrase) inhibitor
famotidine[no description available]low001,3-thiazoles;
guanidines;
sulfonamide		anti-ulcer drug;
H2-receptor antagonist;
P450 inhibitor
furosemide[no description available]low00chlorobenzoic acid;
furans;
sulfonamide		environmental contaminant;
loop diuretic;
xenobiotic
glimepiride[no description available]low00sulfonamide
n-(2-(methylamino)ethyl)-5-isoquinolinesulfonamide[no description available]low00isoquinolines;
sulfonamide
N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide[no description available]low00bromobenzenes;
isoquinolines;
olefinic compound;
secondary amino compound;
sulfonamide		EC 2.7.11.11 (cAMP-dependent protein kinase) inhibitor
hydrochlorothiazide[no description available]low00benzothiadiazine;
organochlorine compound;
sulfonamide		antihypertensive agent;
diuretic;
environmental contaminant;
xenobiotic
hydroxymethyltolbutamide[no description available]low00benzyl alcohols;
sulfonamide;
ureas		metabolite
indapamide[no description available]low00indoles;
organochlorine compound;
sulfonamide		antihypertensive agent;
diuretic
methazolamide[no description available]low00sulfonamide;
thiadiazoles
metolazone[no description available]low00organochlorine compound;
quinazolines;
sulfonamide		antihypertensive agent;
diuretic;
ion transport inhibitor
monodansylcadaverine[no description available]low00aminonaphthalene;
primary amino compound;
sulfonamide;
tertiary amino compound		EC 2.3.2.13 (protein-glutamine gamma-glutamyltransferase) inhibitor;
fluorochrome;
protective agent
n-(4-aminobutyl)-5-chloro-2-naphthalenesulfonamide[no description available]low00naphthalenes;
organochlorine compound;
primary amino compound;
sulfonamide
naratriptan[no description available]low00heteroarylpiperidine;
sulfonamide;
tryptamines		serotonergic agonist;
vasoconstrictor agent
nimesulide[no description available]low00aromatic ether;
C-nitro compound;
sulfonamide		cyclooxygenase 2 inhibitor;
non-steroidal anti-inflammatory drug
n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide[no description available]low00aromatic ether;
C-nitro compound;
sulfonamide		antineoplastic agent;
cyclooxygenase 2 inhibitor
5-[3-(benzenesulfonamido)phenyl]-N-hydroxypent-2-en-4-ynamide[no description available]low00sulfonamide
phthalylsulfathiazole[no description available]low001,3-thiazoles;
dicarboxylic acid monoamide;
sulfonamide antibiotic;
sulfonamide
probenecid[no description available]low00benzoic acids;
sulfonamide		uricosuric drug
sulfadiazine[no description available]low00pyrimidines;
substituted aniline;
sulfonamide antibiotic;
sulfonamide		antiinfective agent;
antimicrobial agent;
antiprotozoal drug;
coccidiostat;
drug allergen;
EC 1.1.1.153 [sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)] inhibitor;
EC 2.5.1.15 (dihydropteroate synthase) inhibitor;
environmental contaminant;
xenobiotic
sotalol[no description available]low00ethanolamines;
secondary alcohol;
secondary amino compound;
sulfonamide		anti-arrhythmia drug;
beta-adrenergic antagonist;
environmental contaminant;
xenobiotic
SU6656[no description available]low00oxindoles;
sulfonamide		antineoplastic agent;
Aurora kinase inhibitor;
EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor
sulfabenzamide[no description available]low00benzenes;
sulfonamide antibiotic;
sulfonamide		antibacterial drug;
antimicrobial drug
sulfacytine[no description available]low00benzenes;
sulfonamide
sulfadimethoxine[no description available]low00aromatic ether;
pyrimidines;
substituted aniline;
sulfonamide antibiotic;
sulfonamide		antiinfective agent;
antimicrobial agent;
drug allergen;
environmental contaminant;
xenobiotic
sulfamerazine[no description available]low00pyrimidines;
sulfonamide antibiotic;
sulfonamide		antiinfective agent;
drug allergen
sulfameter[no description available]low00pyrimidines;
sulfonamide antibiotic;
sulfonamide		antiinfective agent;
leprostatic drug;
renal agent
sulfamethazine[no description available]low00pyrimidines;
sulfonamide antibiotic;
sulfonamide		antibacterial drug;
antiinfective agent;
antimicrobial agent;
carcinogenic agent;
drug allergen;
EC 2.5.1.15 (dihydropteroate synthase) inhibitor;
environmental contaminant;
ligand;
xenobiotic
sulfamethizole[no description available]low00sulfonamide antibiotic;
sulfonamide;
thiadiazoles		antiinfective agent;
antimicrobial agent;
drug allergen;
EC 2.5.1.15 (dihydropteroate synthase) inhibitor
sulfamethoxazole[no description available]low00isoxazoles;
substituted aniline;
sulfonamide antibiotic;
sulfonamide		antibacterial agent;
antiinfective agent;
antimicrobial agent;
drug allergen;
EC 1.1.1.153 [sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)] inhibitor;
EC 2.5.1.15 (dihydropteroate synthase) inhibitor;
environmental contaminant;
epitope;
P450 inhibitor;
xenobiotic
sulfamethoxypyridazine[no description available]low00pyridazines;
sulfonamide antibiotic;
sulfonamide		antiinfective agent;
drug allergen;
EC 2.5.1.15 (dihydropteroate synthase) inhibitor
sulfamonomethoxine[no description available]low00benzenes;
sulfonamide
sulfanilamide[no description available]low00substituted aniline;
sulfonamide antibiotic;
sulfonamide		antibacterial agent;
drug allergen;
EC 4.2.1.1 (carbonic anhydrase) inhibitor
sulfanitran[no description available]low00sulfonamide
sulfaphenazole[no description available]low00primary amino compound;
pyrazoles;
substituted aniline;
sulfonamide antibiotic;
sulfonamide		antibacterial drug;
EC 1.14.13.181 (13-deoxydaunorubicin hydroxylase) inhibitor;
EC 1.14.13.67 (quinine 3-monooxygenase) inhibitor;
P450 inhibitor
sulfapyridine[no description available]low00pyridines;
substituted aniline;
sulfonamide antibiotic;
sulfonamide		antiinfective agent;
dermatologic drug;
drug allergen;
environmental contaminant;
xenobiotic
sulfaquinoxaline[no description available]low00benzenes;
sulfonamide
sulfathiazole[no description available]low001,3-thiazoles;
substituted aniline;
sulfonamide antibiotic;
sulfonamide		antiinfective agent;
drug allergen;
EC 2.5.1.15 (dihydropteroate synthase) inhibitor;
environmental contaminant;
xenobiotic
sulfisomidine[no description available]low00pyrimidines;
sulfonamide antibiotic;
sulfonamide		antiinfective agent
sulfisoxazole[no description available]low00isoxazoles;
sulfonamide antibiotic;
sulfonamide		antibacterial drug;
drug allergen
sulfoxone[no description available]low00sulfonamide
sulpiride[no description available]low00benzamides;
N-alkylpyrrolidine;
sulfonamide		antidepressant;
antiemetic;
antipsychotic agent;
dopaminergic antagonist
sumatriptan[no description available]low00sulfonamide;
tryptamines		serotonergic agonist;
vasoconstrictor agent
delavirdine[no description available]low00aminopyridine;
indolecarboxamide;
N-acylpiperazine;
sulfonamide		antiviral drug;
HIV-1 reverse transcriptase inhibitor
zonisamide[no description available]low001,2-benzoxazoles;
sulfonamide		anticonvulsant;
antioxidant;
central nervous system drug;
protective agent;
T-type calcium channel blocker
4-toluenesulfonamide[no description available]low00sulfonamide
n-methyl-n-nitrosotoluene-p-sulfonamide[no description available]low00sulfonamide
sulfachlorpyridazine[no description available]low00organochlorine compound;
pyridazines;
sulfonamide		antibacterial drug;
drug allergen;
EC 2.5.1.15 (dihydropteroate synthase) inhibitor
acetyl sulfisoxazole[no description available]low00benzenes;
sulfonamide
sulfaethidole[no description available]low00benzenes;
sulfonamide
benzenesulfonamide[no description available]low00sulfonamide
carzenide[no description available]low00sulfonamide
sulfalene[no description available]low00pyrazines;
sulfonamide antibiotic;
sulfonamide
thioproperazine[no description available]low00N-alkylpiperazine;
N-methylpiperazine;
phenothiazines;
sulfonamide		phenothiazine antipsychotic drug
carbutamide[no description available]low00benzenes;
sulfonamide
glymidine[no description available]low00diether;
pyrimidines;
sulfonamide		hypoglycemic agent
thiazosulfone[no description available]low00sulfonamide
glybuthiazol[no description available]low00benzenes;
sulfonamide
sulfanilylurea[no description available]low00benzenes;
sulfonamide
metahexamide[no description available]low00benzenes;
sulfonamide
clopamide[no description available]low00sulfonamide
tolcyclamide[no description available]low00sulfonamide
sulfamoxole[no description available]low00oxazole;
sulfonamide antibiotic;
sulfonamide		antimicrobial agent;
drug allergen
sulfaethoxypyridazine[no description available]low00sulfonamideantibacterial agent
4-((diethylamino)sulfonyl)benzoic acid[no description available]low00sulfonamide
dinsed[no description available]low00sulfonamide
amidephrine[no description available]low00sulfonamide
sulfadoxine[no description available]low00pyrimidines;
sulfonamide		antibacterial drug;
antimalarial
hydroxyhexamide[no description available]low00sulfonamide
asulam[no description available]low00carbamate ester;
primary amino compound;
substituted aniline;
sulfonamide		agrochemical;
EC 2.5.1.15 (dihydropteroate synthase) inhibitor;
environmental contaminant;
herbicide;
xenobiotic
n-butylbenzenesulfonamide[no description available]low00sulfonamideneurotoxin;
plant metabolite
oryzalin[no description available]low00aromatic amine;
C-nitro compound;
sulfonamide;
tertiary amino compound		agrochemical;
antimitotic;
herbicide
glisoxepide[no description available]low00sulfonamide
perfluidone[no description available]low00sulfonamide
mefluidide[no description available]low00sulfonamide
2-aminosulfonyl-benzoic acid methyl ester[no description available]low00benzoate ester;
methyl ester;
sulfonamide		marine xenobiotic metabolite
clorsulon[no description available]low00benzenes;
sulfonamide
agreal[no description available]low00sulfonamide
n-acetylsulfapyridine[no description available]low00sulfonamide
tirofiban[no description available]low00L-tyrosine derivative;
piperidines;
sulfonamide		anticoagulant;
fibrin modulating drug;
platelet glycoprotein-IIb/IIIa receptor antagonist
n(4)-acetylsulfadiazine[no description available]low00acetamides;
pyrimidines;
sulfonamide		marine xenobiotic metabolite
amprenavir[no description available]low00carbamate ester;
sulfonamide;
tetrahydrofuryl ester		antiviral drug;
HIV protease inhibitor
n(4)-acetylsulfamethoxazole[no description available]low00isoxazoles;
sulfonamide		drug metabolite;
marine xenobiotic metabolite
glisentide[no description available]low00sulfonamide
ebrotidine[no description available]low00sulfonamide
4-chlorobenzenesulfonamide[no description available]low00sulfonamide
4-amino-6-chloro-1,3-benzenedisulfonamide[no description available]low00sulfonamide
N(4)-acetylsulfathiazole[no description available]low001,3-thiazoles;
acetamides;
sulfonamide		marine xenobiotic metabolite
2-benzothiazolesulfonamide[no description available]low00benzothiazoles;
sulfonamide
brinzolamide[no description available]low00sulfonamide;
thienothiazine		antiglaucoma drug;
EC 4.2.1.1 (carbonic anhydrase) inhibitor
piloty's acid[no description available]low00sulfonamide
perfluorooctanesulfonamide[no description available]low00perfluorinated compound;
sulfonamide		persistent organic pollutant
uk 68798[no description available]low00aromatic ether;
sulfonamide;
tertiary amino compound		anti-arrhythmia drug;
potassium channel blocker
glyclopyramide[no description available]low00sulfonamide
fluoresone[no description available]low00sulfonamide
2-aminobenzenesulfonamide[no description available]low00benzenes;
sulfonamide
4-chloro-5-sulfamoylanthranilic acid[no description available]low00benzenes;
sulfonamide
sulfluramid[no description available]low00sulfonamideacaricide;
environmental contaminant;
insecticide;
xenobiotic
8-(4-tolylsulfonylamino)quinoline[no description available]low00sulfonamide
n-(2,4-dichloro-5-(4-(difluoromethyl)-4,5-dihydro-3-methyl-5-oxo-1h-1,2,4-triazol-1-yl)phenyl)methanesulfonamide[no description available]low00dichlorobenzene;
organofluorine compound;
sulfonamide;
triazoles		agrochemical;
EC 1.3.3.4 (protoporphyrinogen oxidase) inhibitor;
herbicide
cloransulam-methyl[no description available]low00methyl ester;
monochlorobenzenes;
organofluorine compound;
sulfonamide;
triazolopyrimidines		agrochemical;
EC 2.2.1.6 (acetolactate synthase) inhibitor;
herbicide
sdds[no description available]low00benzenes;
sulfonamide
4-chlorobenzenesulfonylurea[no description available]low00sulfonamide
n-(2,6-difluorophenyl)-5-methyl(1,2,4)-triazol(1,5-a)pyrimidine-2-sulfonamide[no description available]low00sulfonamide
flazasulfuron[no description available]low00pyridines;
sulfonamide
4-methyl-N-(phenylmethyl)benzenesulfonamide[no description available]low00sulfonamide
bosentan anhydrous[no description available]low00primary alcohol;
pyrimidines;
sulfonamide		antihypertensive agent;
endothelin receptor antagonist
sulfamethoxazole hydroxylamine[no description available]low00isoxazoles;
sulfonamide		allergen;
metabolite
gr 113808[no description available]low00indolyl carboxylate ester;
piperidines;
sulfonamide		serotonergic antagonist
valdecoxib[no description available]low00isoxazoles;
sulfonamide		antipyretic;
antirheumatic drug;
cyclooxygenase 2 inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug
ym 12617[no description available]low00aromatic ether;
secondary amino compound;
sulfonamide
dansyllysine[no description available]low00L-lysine derivative;
non-proteinogenic L-alpha-amino acid;
sulfonamide		epitope
almotriptan[no description available]low00indoles;
sulfonamide;
tertiary amine		non-steroidal anti-inflammatory drug;
serotonergic agonist;
vasoconstrictor agent
4-nitrososulfamethoxazole[no description available]low00isoxazoles;
nitroso compound;
sulfonamide		allergen;
metabolite
cki 7[no description available]low00isoquinolines;
organochlorine compound;
primary amino compound;
sulfonamide		EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor
fosamprenavir[no description available]low00sulfonamideprodrug
metipamide[no description available]low00sulfonamide
jte 522[no description available]low001,3-oxazoles;
organofluorine compound;
sulfonamide		cyclooxygenase 2 inhibitor
carboxytolbutamide[no description available]low00sulfonamide
tevenel[no description available]low00sulfonamide
sulfachlorpyrazine[no description available]low00sulfonamide
n(4)-acetylsulfadimethoxine[no description available]low00acetamides;
pyrimidines;
sulfonamide		marine xenobiotic metabolite
dronedarone[no description available]low001-benzofurans;
aromatic ether;
aromatic ketone;
sulfonamide;
tertiary amino compound		anti-arrhythmia drug;
environmental contaminant;
xenobiotic
darunavir[no description available]low00carbamate ester;
furofuran;
sulfonamide		antiviral drug;
HIV protease inhibitor
cimicoxib[no description available]low00aromatic ether;
imidazoles;
organochlorine compound;
organofluorine compound;
sulfonamide		cyclooxygenase 2 inhibitor;
non-steroidal anti-inflammatory drug
dabuzalgron[no description available]low00aromatic ether;
imidazoles;
monochlorobenzenes;
sulfonamide		alpha-adrenergic agonist
n-(3-chloro-7-indolyl)-1,4-benzenedisulphonamide[no description available]low00chloroindole;
organochlorine compound;
sulfonamide		antineoplastic agent;
EC 4.2.1.1 (carbonic anhydrase) inhibitor
3,4-Dichlorobenzenesulfonamide[no description available]low00sulfonamide
N-cyclooctyl-4-methylbenzenesulfonamide[no description available]low00sulfonamide
tolpyrramide[no description available]low00sulfonamide
acetic acid [2-[acetyl-(4-methylphenyl)sulfonylamino]phenyl] ester[no description available]low00sulfonamide
1-(benzenesulfonyl)indole[no description available]low00sulfonamide
tosylphenylalanyl chloromethyl ketone[no description available]low00alpha-chloroketone;
sulfonamide		alkylating agent;
serine proteinase inhibitor
rosuvastatin[no description available]low00dihydroxy monocarboxylic acid;
monofluorobenzenes;
pyrimidines;
statin (synthetic);
sulfonamide		anti-inflammatory agent;
antilipemic drug;
cardioprotective agent;
CETP inhibitor;
environmental contaminant;
xenobiotic
bms 214662[no description available]low00benzenes;
benzodiazepine;
imidazoles;
nitrile;
sulfonamide;
thiophenes		antineoplastic agent;
apoptosis inducer;
EC 2.5.1.58 (protein farnesyltransferase) inhibitor
N-[4-(methanesulfonamido)phenyl]acetamide[no description available]low00sulfonamide
prinomastat[no description available]low00aromatic ether;
hydroxamic acid;
pyridines;
sulfonamide;
thiomorpholines		antineoplastic agent;
EC 3.4.24.35 (gelatinase B) inhibitor;
matrix metalloproteinase inhibitor
glucosulfone[no description available]low00sulfonamide
1-[1-(benzenesulfonyl)-3-pyrrolyl]ethanone[no description available]low00sulfonamide
1-(4-bromo-2,5-dimethoxyphenyl)sulfonylazepane[no description available]low00sulfonamide
1-(4-chloro-3-methoxyphenyl)sulfonylazepane[no description available]low00sulfonamide
6-[(4-methylphenyl)sulfonyl]-6-azabicyclo[3.2.1]octane[no description available]low00sulfonamide
N-cyclopentyl-4-[[4-[2-furanyl(oxo)methyl]-1-piperazinyl]sulfonyl]benzenesulfonamide[no description available]low00sulfonamide
N4-cyclohexyl-N1-ethyl-N4-(2-pyridinylmethyl)benzene-1,4-disulfonamide[no description available]low00sulfonamide
2-[cyclohexyl-(2,4,6-trimethylphenyl)sulfonylamino]-N-(3-pyridinylmethyl)acetamide[no description available]low00sulfonamide
1-(3-chloro-4-methoxyphenyl)sulfonyl-N-(3-pyridinyl)-3-piperidinecarboxamide[no description available]low00sulfonamide
N-(3-ethoxyphenyl)-1-(4-methoxyphenyl)sulfonyl-3-piperidinecarboxamide[no description available]low00sulfonamide
N-[4-[[4-(4-methylphenyl)sulfonyl-1,4-diazepan-1-yl]sulfonyl]phenyl]acetamide[no description available]low00sulfonamide
N-[2-(2-furanylmethylthio)ethyl]-4-methoxybenzenesulfonamide[no description available]low00sulfonamide
4-[2-[1-(4-methoxyphenyl)sulfonyl-2-benzimidazolyl]ethyl]morpholine[no description available]low00sulfonamide
1-(2,5-dimethoxyphenyl)sulfonyl-N-(phenylmethyl)-4-piperidinecarboxamide[no description available]low00sulfonamide
1-[2-chloro-5-(trifluoromethyl)phenyl]sulfonylazepane[no description available]low00sulfonamide
4-[4-[(5,6-dimethyl-1-benzimidazolyl)sulfonyl]phenyl]sulfonylmorpholine[no description available]low00sulfonamide
1-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-4-(4-methoxyphenyl)sulfonylpiperazine[no description available]low00sulfonamide
4-methyl-N-(pyridin-4-ylmethyl)benzenesulfonamide[no description available]low00sulfonamide
N-cyclopropyl-4-(2,3-dihydroindol-1-ylsulfonyl)benzenesulfonamide[no description available]low00sulfonamide
2-[4-(benzenesulfonyl)phenyl]-5-(3,4,5-trimethoxyphenyl)-1,3,4-oxadiazole[no description available]low00sulfonamide
N-(2-furanylmethyl)-2-[(4-methoxyphenyl)sulfonylamino]benzamide[no description available]low00sulfonamide
N-[4-(diethylsulfamoyl)phenyl]-2-(2-oxo-1,3-benzothiazol-3-yl)acetamide[no description available]low00sulfonamide
3-[[4-(1-benzotriazolyl)-1-piperidinyl]sulfonyl]-N-cyclopentylbenzenesulfonamide[no description available]low00sulfonamide
N,N-dimethyl-4-[[4-(5-methyl-1-benzotriazolyl)-1-piperidinyl]sulfonyl]benzamide[no description available]low00sulfonamide
4-(4-methoxyphenyl)sulfonyl-N-(phenylmethyl)-1-piperazinecarboxamide[no description available]low00sulfonamide
N-[4-(4-fluorophenyl)-2-thiazolyl]-2-[(4-methylphenyl)sulfonylamino]benzamide[no description available]low00sulfonamide
N-(4-{[2-(pyridin-3-yl)piperidin-1-yl]sulfonyl}phenyl)acetamide[no description available]low00acetamides;
piperidines;
pyridines;
sulfonamide
3,4,5-trimethoxy-N-[2-(4-sulfamoylphenyl)ethyl]benzamide[no description available]low00sulfonamide
N-(4-phenylmethoxyphenyl)methanesulfonamide[no description available]low00sulfonamide
3-(diethylsulfamoyl)-N-(1,3,4-thiadiazol-2-yl)benzamide[no description available]low00sulfonamide
2-[(4-fluoro-3-methylphenyl)sulfonylamino]acetic acid[no description available]low00sulfonamide
N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-thiophenesulfonamide[no description available]low00sulfonamide
N-(2-furanylmethyl)-4-methyl-N-(phenylmethyl)benzenesulfonamide[no description available]low00sulfonamide
2-(2-ethylphenoxy)-N-(4-sulfamoylphenyl)acetamide[no description available]low00sulfonamide
1-(4-chlorophenyl)-3-(4-sulfamoylphenyl)urea[no description available]low00sulfonamide
N-(3-chloro-4-hydroxy-2,5-dimethylphenyl)benzenesulfonamide[no description available]low00sulfonamide
2,4,6-trimethyl-n-(meta-3-trifluoromethylphenyl)benzenesulfonamide[no description available]low00sulfonamide
4-[(4-phenyl-2-thiazolyl)amino]benzenesulfonamide[no description available]low00sulfonamide
N-[2-(1-cyclohexenyl)ethyl]-2,5-dimethoxybenzenesulfonamide[no description available]low00sulfonamide
N-(1-ethyl-5-benzimidazolyl)-4-methylbenzenesulfonamide[no description available]low00sulfonamide
4-methyl-N-(5,6,7,8-tetrahydronaphthalen-1-yl)benzenesulfonamide[no description available]low00sulfonamide
4-chloro-N-(4-hydrazinyl-6-methyl-2-pyrimidinyl)benzenesulfonamide[no description available]low00sulfonamide
4-amino-N-(4-ethoxyphenyl)benzenesulfonamide[no description available]low00benzenes;
sulfonamide
1-(2-nitrophenyl)sulfonylpiperidine[no description available]low00sulfonamide
N,4-dimethyl-N-(4-methylphenyl)benzenesulfonamide[no description available]low00sulfonamide
2,3,4-trimethyl-N-(3-pyridinyl)benzenesulfonamide[no description available]low00sulfonamide
2-[[4-(1-pyrrolidinylsulfonyl)phenyl]hydrazinylidene]propanedinitrile[no description available]low00sulfonamide
N-[1-(benzenesulfonyl)-2,2-dichloroethenyl]acetamide[no description available]low00sulfonamide
2-(4-fluoro-N-methylsulfonylanilino)-N-(3-methylphenyl)acetamide[no description available]low00sulfonamide
4-chloro-3-ethoxy-N-(4-ethylphenyl)benzenesulfonamide[no description available]low00sulfonamide
1-(3-chlorophenyl)sulfonylpyrrolidine[no description available]low00sulfonamide
1-cyclopropyl-3-(4-sulfamoylphenyl)thiourea[no description available]low00sulfonamide
N-[3-[methyl(methylsulfonyl)amino]phenyl]-2-phenoxyacetamide[no description available]low00sulfonamide
4-[methyl(methylsulfonyl)amino]-N-(2-phenylethyl)benzamide[no description available]low00sulfonamide
2-(2,6-dichloroanilino)-3-pyridinesulfonamide[no description available]low00pyridines;
sulfonamide
4-(4-chloroanilino)-3-pyridinesulfonamide[no description available]low00pyridines;
sulfonamide
1-ethyl-3-(4-methylphenyl)sulfonylthiourea[no description available]low00sulfonamide
6-chloro-N-(2-hydroxyphenyl)-3-pyridinesulfonamide[no description available]low00pyridines;
sulfonamide
5-chloro-2-methoxy-N,N,4-trimethylbenzenesulfonamide[no description available]low00sulfonamide
2-[(2,5-dimethoxyphenyl)sulfonyl-methylamino]acetic acid[no description available]low00sulfonamide
N-(2-ethylphenyl)-2-methoxy-5-methylbenzenesulfonamide[no description available]low00sulfonamide
4-ethoxy-N-(4-fluorophenyl)-2,3-dimethylbenzenesulfonamide[no description available]low00sulfonamide
N-[2-(1-cyclohexenyl)ethyl]-4-[methyl(methylsulfonyl)amino]benzamide[no description available]low00sulfonamide
1-(2,5-dimethoxyphenyl)sulfonyl-4-ethylpiperazine[no description available]low00sulfonamide
N-[2-(methylthio)phenyl]-2,3-dihydro-1,4-benzodioxin-6-sulfonamide[no description available]low00sulfonamide
N-(4-methoxyphenyl)-4-(methylthio)benzenesulfonamide[no description available]low00sulfonamide
2-methoxy-5-propan-2-yl-N-(2-pyridinyl)benzenesulfonamide[no description available]low00sulfonamide
2,3,5,6-tetramethyl-N-(2-methyl-1,3-benzothiazol-5-yl)benzenesulfonamide[no description available]low00sulfonamide
2-[4-chloro-2-methyl-5-(2-pyridinylsulfamoyl)phenoxy]acetamide[no description available]low00sulfonamide
N-(3-chlorophenyl)-N-[2-(3,4-dihydro-1H-isoquinolin-2-yl)-2-oxoethyl]-4-methylbenzenesulfonamide[no description available]low00sulfonamide
N-[4-(6-methyl-1,3-benzothiazol-2-yl)phenyl]-2-(3-methyl-N-methylsulfonylanilino)acetamide[no description available]low00sulfonamide
2-[(5-bromo-2-thiophenyl)sulfonylamino]-N-(2-furanylmethyl)benzamide[no description available]low00sulfonamide
N-[4-[(2,6-dimethoxy-4-pyrimidinyl)sulfamoyl]phenyl]butanamide[no description available]low00sulfonamide
2-(3-pyridinyl)-4-[4-(1-pyrrolidinylsulfonyl)phenyl]thiazole[no description available]low00sulfonamide
5-bromo-6-chloro-N-(4-methyl-2-pyridinyl)-3-pyridinesulfonamide[no description available]low00pyridines;
sulfonamide
4-(4-fluorophenyl)sulfonyl-2-(2-furanyl)-N-phenyl-5-oxazolamine[no description available]low00sulfonamide
2-[[4-(4-methylphenyl)sulfonyl-1-piperazinyl]methyl]-4-propan-2-ylphenol[no description available]low00sulfonamide
ethyl 4-{N-[(4-chlorophenyl)sulfonyl]-N-methylglycyl}piperazine-1-carboxylate[no description available]low00carbamate ester;
sulfonamide
N-[(2-chlorophenyl)methyl]-1-(4-methylphenyl)sulfonyl-4-piperidinecarboxamide[no description available]low00sulfonamide
N-[4-(1-pyrrolidinylsulfonyl)phenyl]-2-thiophen-2-ylacetamide[no description available]low00sulfonamide
2-[methyl-(2,4,6-trimethylphenyl)sulfonylamino]-N-(2-pyridinylmethyl)acetamide[no description available]low00sulfonamide
2-[(4-ethoxyphenyl)sulfonylamino]-N-(2-furanylmethyl)benzamide[no description available]low00sulfonamide
1-(4-methylphenyl)sulfonyl-2-benzimidazolamine[no description available]low00sulfonamide
1-(4-chlorophenyl)sulfonyl-2-benzimidazolamine[no description available]low00sulfonamide
N-[4-(1-pyrrolidinylsulfonyl)phenyl]-2-(1,1,3-trioxo-1,2-benzothiazol-2-yl)acetamide[no description available]low00sulfonamide
N-[4-(1-piperidinylsulfonyl)phenyl]-2-thiophenesulfonamide[no description available]low00sulfonamide
N-(1,3-benzothiazol-2-yl)-2-[methyl-(4-methylphenyl)sulfonylamino]acetamide[no description available]low00sulfonamide
1-cyclohexyl-3-[4-[(5-methyl-3-isoxazolyl)sulfamoyl]phenyl]urea[no description available]low00sulfonamide
N-(5-chloro-2-hydroxyphenyl)-1,3-dimethyl-2-oxo-5-benzimidazolesulfonamide[no description available]low00sulfonamide
2,5-dichloro-4-ethoxy-N-(2-pyridinylmethyl)benzenesulfonamide[no description available]low00sulfonamide
4-ethoxy-2,3,5-trimethyl-N-(3-pyridinylmethyl)benzenesulfonamide[no description available]low00sulfonamide
N-[4-[(3,4-dimethoxyphenyl)sulfamoyl]phenyl]acetamide[no description available]low00sulfonamide
3-(1-piperidinylsulfonyl)-N-(2-thiazolyl)benzamide[no description available]low00sulfonamide
4-chloro-3-(1-piperidinylsulfonyl)-N-(2-thiazolyl)benzamide[no description available]low00sulfonamide
2-[N-(benzenesulfonyl)-4-ethoxyanilino]-N-(2-methoxyphenyl)acetamide[no description available]low00sulfonamide
1-(2,5-dimethoxyphenyl)sulfonyl-4-(phenylmethyl)piperazine[no description available]low00sulfonamide
4-[(4-chlorophenyl)methyl-methylsulfonylamino]-N-(2-pyridinylmethyl)benzamide[no description available]low00sulfonamide
5-bromo-2-methoxy-N-(3-methyl-2-pyridinyl)benzenesulfonamide[no description available]low00sulfonamide
pyrabactin[no description available]low00naphthalenes;
organobromine compound;
pyridines;
sulfonamide		abscisic acid receptor agonist;
hormone;
plant growth regulator
2-(4-methoxyphenyl)-N-[4-[(5-methyl-3-isoxazolyl)sulfamoyl]phenyl]acetamide[no description available]low00sulfonamide
1,4-bis[(4-methoxy-2-methylphenyl)sulfonyl]-1,4-diazepane[no description available]low00sulfonamide
N-(2-furanylmethyl)-4-(1-pyrrolidinylsulfonyl)benzenesulfonamide[no description available]low00sulfonamide
4-(benzenesulfonyl)-N-methyl-N-phenyl-1-piperazinecarboxamide[no description available]low00sulfonamide
2-(3-ethylphenoxy)-N-[4-(2-pyridinylsulfamoyl)phenyl]acetamide[no description available]low00sulfonamide
N-[[1-(benzenesulfonyl)-4-piperidinyl]methyl]benzenesulfonamide[no description available]low00sulfonamide
1-(1,3-benzodioxol-5-yl)-3-[4-[(5-methyl-3-isoxazolyl)sulfamoyl]phenyl]urea[no description available]low00sulfonamide
1-(1,3-benzodioxol-5-yl)-3-[4-[(phenylmethyl)sulfamoyl]phenyl]urea[no description available]low00sulfonamide
1,3-diethyl-6-methyl-N-(2-methylphenyl)-2-oxo-5-benzimidazolesulfonamide[no description available]low00sulfonamide
N-(1,3-benzodioxol-5-ylmethyl)-4-methyl-3-(1-piperidinylsulfonyl)benzamide[no description available]low00sulfonamide
3-(1-azepanylsulfonyl)-N-(3-isoxazolyl)-4-methylbenzamide[no description available]low00sulfonamide
1-methylsulfonyl-N-(6,7,8,9-tetrahydrodibenzofuran-2-yl)-2,3-dihydroindole-5-sulfonamide[no description available]low00sulfonamide
2-[2-chloro-4-(2,3-dihydroindol-1-ylsulfonyl)phenoxy]-N-(2-pyridinylmethyl)acetamide[no description available]low00sulfonamide
1-(4-bromo-3-ethoxyphenyl)sulfonyl-3,5-dimethylpyrazole[no description available]low00sulfonamide
N-(4-hydroxy-3,5-dimethylphenyl)-2,5-dimethyl-3-thiophenesulfonamide[no description available]low00sulfonamide
5-[(5-tert-butyl-2,3-dimethylphenyl)sulfonylamino]-2-hydroxybenzoic acid[no description available]low00sulfonamide
1-(4-chloro-2,5-dimethoxyphenyl)sulfonylbenzotriazole[no description available]low00sulfonamide
2-[4-chloro-5-(cyclopentylsulfamoyl)-2-methylphenoxy]-N-cyclohexylacetamide[no description available]low00sulfonamide
2-(1,3-benzothiazol-2-ylthio)-N-(4-methylphenyl)sulfonylacetamide[no description available]low00sulfonamide
2,4-dichloro-5-(diethylsulfamoyl)-N-(1,3,4-thiadiazol-2-yl)benzamide[no description available]low00sulfonamide
N-cycloheptyl-1-(4-methylphenyl)sulfonyl-4-piperidinecarboxamide[no description available]low00sulfonamide
N-(2-methyl-1,3-benzothiazol-6-yl)-4-(4-morpholinylsulfonyl)benzamide[no description available]low00sulfonamide
4-(dimethylsulfamoyl)-N-(4-thiophen-2-yl-2-thiazolyl)benzamide[no description available]low00sulfonamide
2-[1-(4-tert-butylphenyl)sulfonyl-4-piperidinyl]-6-chloro-1H-benzimidazole[no description available]low00sulfonamide
2-[[5-(1H-benzimidazol-2-yl)-2-pyridinyl]thio]-N-[4-(1-pyrrolidinylsulfonyl)phenyl]acetamide[no description available]low00sulfonamide
4-[[3-[(2-chlorophenyl)methyl]-5-cyclopropyl-7-triazolo[4,5-d]pyrimidinyl]amino]-N,N-dimethylbenzenesulfonamide[no description available]low00sulfonamide
7-methyl-2-[4-(4-methylphenyl)sulfonyl-1,4-diazepan-1-yl]-3-quinolinecarbonitrile[no description available]low00sulfonamide
6-amino-5-(benzenesulfonyl)-2-methoxy-3-pyridinecarbonitrile[no description available]low00sulfonamide
6-amino-5-(4-chlorophenyl)sulfonyl-2-oxo-1H-pyridine-3-carbonitrile[no description available]low00sulfonamide
2-[benzenesulfonyl(2-pyridinyl)amino]acetic acid[no description available]low00sulfonamide
2-[(4-chlorophenyl)sulfonyl-(2-pyridinyl)amino]acetic acid[no description available]low00sulfonamide
2,5-dichloro-N-(1,5,6-trimethyl-4-benzimidazolyl)benzenesulfonamide[no description available]low00sulfonamide
2-[(4-fluorophenyl)sulfonyl-(2-pyridinyl)amino]-N-phenylacetamide[no description available]low00sulfonamide
5-[1-(benzenesulfonyl)-3-pyrazolyl]-2-phenylthiazole[no description available]low00sulfonamide
5-[1-(4-fluorophenyl)sulfonyl-3-pyrazolyl]-2-phenylthiazole[no description available]low00sulfonamide
N-[1-[(3,4-dichlorophenyl)methyl]-6-oxo-3-pyridinyl]benzenesulfonamide[no description available]low00sulfonamide
2-(benzenesulfonylmethyl)-5-(4-chlorophenyl)cyclohexane-1,3-dione[no description available]low00sulfonamide
1-(benzenesulfonyl)-3-pyrazolidinone[no description available]low00sulfonamide
N-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-methyl-4-pyrazolesulfonamide[no description available]low00sulfonamide
N-(4-methoxyphenyl)-2-(3-methylphenoxy)-N-(4-methylphenyl)sulfonylacetamide[no description available]low00sulfonamide
N-[4-(4-fluorophenyl)-2-thiazolyl]-4-methylbenzenesulfonamide[no description available]low00sulfonamide
2-[[[4-(diethylsulfamoyl)phenyl]-oxomethyl]amino]-4-methyl-5-thiazolecarboxylic acid ethyl ester[no description available]low00sulfonamide
tosylarginine methyl ester[no description available]low00guanidines;
L-arginine ester;
methyl ester;
sulfonamide
n-(4-(n-(3-methoxypyrazin-2-yl)sulfamoyl)phenyl)-3-(5-nitrothiophene-2-yl)acrylamide[no description available]low00pyrazines;
sulfonamide;
thiophenes		necroptosis inhibitor;
neuroprotective agent
N-[(benzenesulfonylhydrazo)-sulfanylidenemethyl]-4-methylbenzamide[no description available]low00sulfonamide
xl147[no description available]low00aromatic amine;
benzothiadiazole;
quinoxaline derivative;
sulfonamide		antineoplastic agent;
EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor
7-chloro-2-methyl-4-(4-methylphenyl)sulfonylthiazolo[5,4-b]indole[no description available]low00sulfonamide
N-(5-cyclopropyl-1,3,4-oxadiazol-2-yl)-4-[(4-methyl-1-piperidinyl)sulfonyl]benzamide[no description available]low00sulfonamide
N-(5-cyclopropyl-1,3,4-oxadiazol-2-yl)-4-[methyl-(phenylmethyl)sulfamoyl]benzamide[no description available]low00sulfonamide
4-(4-bromophenyl)sulfonyl-2-(2-furanyl)-5-(methylthio)oxazole[no description available]low00sulfonamide
4-(4-morpholinylsulfonyl)-N-(5-thiophen-2-yl-1,3,4-oxadiazol-2-yl)benzamide[no description available]low00sulfonamide
1-[4-(benzenesulfonyl)-1-piperazinyl]-2-[(4-fluorophenyl)thio]ethanone[no description available]low00sulfonamide
4-methoxy-N-(3-methylbutyl)-3-(4-morpholinylsulfonyl)benzamide[no description available]low00sulfonamide
N-(1,3-benzothiazol-2-yl)-3-(2,3-dihydroindol-1-ylsulfonyl)benzamide[no description available]low00sulfonamide
N-(1H-benzimidazol-2-yl)-3-[phenyl(prop-2-enyl)sulfamoyl]benzamide[no description available]low00sulfonamide
1-[4-(4-chlorophenyl)sulfonyl-1-piperazinyl]-2-[(5,7-dimethyl-[1,2,4]triazolo[4,3-a]pyrimidin-3-yl)thio]ethanone[no description available]low00sulfonamide
3-[4-(4-morpholinylsulfonyl)phenyl]propanoic acid [2-[(5-chloro-2-pyridinyl)amino]-2-oxoethyl] ester[no description available]low00sulfonamide
2-[(5-chloro-2-thiophenyl)sulfonylamino]-N-(2-furanylmethyl)benzamide[no description available]low00sulfonamide
1-[4-(benzenesulfonyl)-1-piperazinyl]-2-[[3-chloro-5-(trifluoromethyl)-2-pyridinyl]thio]ethanone[no description available]low00sulfonamide
2,5-difluoro-N-[2-(4-morpholinylmethyl)-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-4-yl]benzenesulfonamide[no description available]low00sulfonamide
N-[5-(ethylthio)-1,3,4-thiadiazol-2-yl]-3-[methyl-(4-methylphenyl)sulfamoyl]benzamide[no description available]low00sulfonamide
N-(2-methyl-1,3-benzothiazol-6-yl)-2,3-dihydro-1,4-benzodioxin-6-sulfonamide[no description available]low00sulfonamide
3-[(4-acetyl-1-piperazinyl)sulfonyl]-N-(1H-benzimidazol-2-yl)benzamide[no description available]low00sulfonamide
3-[(3-hydroxy-5-benzotriazolyl)sulfonylamino]benzoic acid[no description available]low00sulfonamide
3-[(5-chloro-2,4-dimethoxyphenyl)-methylsulfamoyl]-N-(5-cyclopropyl-1,3,4-thiadiazol-2-yl)benzamide[no description available]low00sulfonamide
2-(2-fluorophenoxy)-N-[4-(2-furanylmethylsulfamoyl)phenyl]acetamide[no description available]low00sulfonamide
3-[[[5-[3-(1-piperidinylsulfonyl)phenyl]-1,3,4-oxadiazol-2-yl]thio]methyl]-1,2,3-benzotriazin-4-one[no description available]low00sulfonamide
N-(1H-benzimidazol-2-yl)-3-[methyl-(4-methylphenyl)sulfamoyl]benzamide[no description available]low00sulfonamide
2,6-dichloro-N-[2-(methylthio)-1,3-benzothiazol-6-yl]benzenesulfonamide[no description available]low00sulfonamide
4-fluoro-3-methoxy-N-(2-pyridinyl)benzenesulfonamide[no description available]low00sulfonamide
N-(5-ethyl-1,3,4-oxadiazol-2-yl)-4-[methyl(phenyl)sulfamoyl]benzamide[no description available]low00sulfonamide
4-[bis(2-methoxyethyl)sulfamoyl]-N-(5-cyclopropyl-1,3,4-oxadiazol-2-yl)benzamide[no description available]low00sulfonamide
4-(dipropylsulfamoyl)-N-[5-[(methylthio)methyl]-1,3,4-oxadiazol-2-yl]benzamide[no description available]low00sulfonamide
4-[butyl(methyl)sulfamoyl]-N-[5-[(methylthio)methyl]-1,3,4-oxadiazol-2-yl]benzamide[no description available]low00sulfonamide
4-[ethyl-(phenylmethyl)sulfamoyl]-N-(5-methyl-1,3,4-oxadiazol-2-yl)benzamide[no description available]low00sulfonamide
4-[ethyl-(phenylmethyl)sulfamoyl]-N-[5-(2-methoxyphenyl)-1,3,4-oxadiazol-2-yl]benzamide[no description available]low00sulfonamide
4-[bis(2-methylpropyl)sulfamoyl]-N-[5-(3-methoxyphenyl)-1,3,4-oxadiazol-2-yl]benzamide[no description available]low00sulfonamide
1-[4-(benzenesulfonyl)-1-piperazinyl]-2-[(4-methyl-2-thiazolyl)thio]ethanone[no description available]low00sulfonamide
1-[4-(benzenesulfonyl)-1-piperazinyl]-2-[(4-ethyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)thio]ethanone[no description available]low00sulfonamide
N-[5-(2-methylpropyl)-1,3,4-thiadiazol-2-yl]-4-nitrobenzenesulfonamide[no description available]low00sulfonamide
2-[(5-butyl-1H-1,2,4-triazol-3-yl)thio]-N-(4-sulfamoylphenyl)acetamide[no description available]low00sulfonamide
2-ethoxy-N-[4-(2-pyrimidinylsulfamoyl)phenyl]acetamide[no description available]low00sulfonamide
N-[4-(dibutylsulfamoyl)phenyl]-2-thiophen-2-ylacetamide[no description available]low00sulfonamide
2,3-dichloro-4-methoxy-N-(3-methoxypropyl)benzenesulfonamide[no description available]low00sulfonamide
2-[(3-cyano-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-2-yl)thio]-N-[4-[(3,4-dimethyl-5-isoxazolyl)sulfamoyl]phenyl]acetamide[no description available]low00sulfonamide
N-(2-furanylmethyl)-2-[4-(propylsulfamoyl)phenoxy]acetamide[no description available]low00sulfonamide
4-(benzenesulfonamido)-N-(5-ethyl-1,3,4-thiadiazol-2-yl)benzamide[no description available]low00sulfonamide
4-methyl-N-[2-(phenylmethyl)-3,4-dihydro-1H-pyrazino[1,2-a]benzimidazol-8-yl]benzenesulfonamide[no description available]low00sulfonamide
2-[4-chloro-5-(cyclohexylsulfamoyl)-2-methylphenoxy]-N-(1,3,4-thiadiazol-2-yl)acetamide[no description available]low00sulfonamide
N-[2-(cyclohexylthio)ethyl]-4-methyl-3-[(4-methylphenyl)sulfamoyl]benzamide[no description available]low00sulfonamide
1-(3-chlorophenyl)-3-[3-[methyl(methylsulfonyl)amino]phenyl]urea[no description available]low00sulfonamide
N-[4-(cyanomethyl)phenyl]-4-cyclohexylbenzenesulfonamide[no description available]low00sulfonamide
N-(4-ethoxyphenyl)-4-[[4-(methylthio)phenyl]sulfonylamino]benzenesulfonamide[no description available]low00sulfonamide
2-(methanesulfonamido)-N-[2-(phenylmethylthio)ethyl]benzamide[no description available]low00sulfonamide
N-(2-fluorophenyl)-4-methoxy-2,5-dimethylbenzenesulfonamide[no description available]low00sulfonamide
2-[benzenesulfonyl-(phenylmethyl)amino]-N-ethylacetamide[no description available]low00sulfonamide
4-[benzenesulfonyl(methyl)amino]-N-[2-[(4-chlorophenyl)methylthio]ethyl]benzamide[no description available]low00sulfonamide
N-(3,4-dimethyl-2-sulfanylidene-5-thiazolyl)carbamic acid 2-[(2,5-dimethylphenyl)sulfonylamino]ethyl ester[no description available]low00sulfonamide
2-[cyclohexyl-(4-methylphenyl)sulfonylamino]-N-(3-methoxypropyl)acetamide[no description available]low00sulfonamide
N-[4-[(4-sulfamoylphenyl)sulfamoyl]phenyl]cyclopropanecarboxamide[no description available]low00sulfonamide
N-(1H-benzimidazol-2-yl)-4-(dimethylsulfamoyl)benzamide[no description available]low00sulfonamide
1-(3-chlorophenyl)-3-[2-(thiophen-2-ylsulfonylamino)phenyl]urea[no description available]low00sulfonamide
2-[4-methyl-3-(1-piperidinylsulfonyl)phenyl]-1,2-benzothiazol-3-one[no description available]low00sulfonamide
N-(1H-benzimidazol-2-ylmethyl)-3-(1-pyrrolidinylsulfonyl)benzamide[no description available]low00sulfonamide
2-[(4-fluoro-2-methylphenyl)sulfonylamino]-N-(3-pyridinylmethyl)benzamide[no description available]low00sulfonamide
2-[(4-cyanophenyl)methylthio]-N-(2-methoxyphenyl)-1,3-benzoxazole-5-sulfonamide[no description available]low00sulfonamide
2-[[5-(4-methylanilino)-1,3,4-thiadiazol-2-yl]thio]-N-[4-(4-morpholinylsulfonyl)phenyl]acetamide[no description available]low00sulfonamide
3-(1-azepanylsulfonyl)-4-chloro-N-(1H-1,2,4-triazol-5-yl)benzamide[no description available]low00sulfonamide
N-(1H-benzimidazol-2-ylmethyl)-4-(1-pyrrolidinylsulfonyl)benzamide[no description available]low00sulfonamide
2-[(4-chlorophenyl)methylthio]-5-[3-(1-piperidinylsulfonyl)phenyl]-1,3,4-oxadiazole[no description available]low00sulfonamide
4-chloro-3-[(4-chlorophenyl)sulfamoyl]-N-(1H-1,2,4-triazol-5-yl)benzamide[no description available]low00sulfonamide
1-(2-fluorophenyl)-1-cyclopentanecarboxylic acid [2-oxo-2-(4-sulfamoylanilino)ethyl] ester[no description available]low00sulfonamide
3-[(4-methyl-1-piperazinyl)sulfonyl]-N-(4-phenyl-2-thiazolyl)benzamide[no description available]low00sulfonamide
N-(2-methoxyphenyl)-2-(2-oxopropylthio)-1,3-benzoxazole-5-sulfonamide[no description available]low00sulfonamide
2-[5-(1-pyrrolidinylsulfonyl)-2-thiophenyl]-N-[2-(4-sulfamoylphenyl)ethyl]acetamide[no description available]low00sulfonamide
1-(4-fluorophenyl)-1-cyclopentanecarboxylic acid [2-oxo-2-(4-sulfamoylanilino)ethyl] ester[no description available]low00sulfonamide
3-(2-chlorophenyl)sulfonylpropanoic acid [2-[(3,5-dichloro-6-methyl-2-pyridinyl)amino]-2-oxoethyl] ester[no description available]low00sulfonamide
2-[4-[benzenesulfonyl(methyl)amino]phenoxy]-N-(1,3-benzothiazol-2-yl)acetamide[no description available]low00sulfonamide
N-(6-methoxy-1,3-benzothiazol-2-yl)-3-(4-morpholinylsulfonyl)benzamide[no description available]low00sulfonamide
N-cyclopentyl-3,4-dimethylbenzenesulfonamide[no description available]low00sulfonamide
6-amino-1-(2-methoxyethyl)-N-(4-methylphenyl)sulfonyl-2,4-dioxo-5-pyrimidinecarboxamide[no description available]low00sulfonamide
3-(benzenesulfonyl)propanoic acid [2-[(3,5-dichloro-4-methyl-2-pyridinyl)amino]-2-oxoethyl] ester[no description available]low00sulfonamide
N-[[2-cyanoethyl(methyl)amino]-sulfanylidenemethyl]-4-(4-morpholinylsulfonyl)benzamide[no description available]low00sulfonamide
[4-methoxy-3-(4-morpholinylsulfonyl)phenyl]-(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)methanone[no description available]low00sulfonamide
[4-(4-bromo-2-chlorophenyl)sulfonyl-1-piperazinyl]-(2-sulfanylidene-1H-pyridin-3-yl)methanone[no description available]low00sulfonamide
[1-(4-fluorophenyl)sulfonyl-4-piperidinyl]-(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)methanone[no description available]low00sulfonamide
N-[(1S)-1-(1H-benzimidazol-2-yl)-2-methylpropyl]-3-(1-pyrrolidinylsulfonyl)benzamide[no description available]low00sulfonamide
1-[4-(3-chloro-2,4,6-trifluorophenyl)sulfonyl-1-piperazinyl]ethanone[no description available]low00sulfonamide
1-[4-(benzenesulfonyl)-1-piperazinyl]-2-[4-(1,3,4-oxadiazol-2-yl)phenoxy]ethanone[no description available]low00sulfonamide
2-(4-methoxyphenyl)-N-[4-(2-pyrimidinylsulfamoyl)phenyl]acetamide[no description available]low00sulfonamide
N1-[4-(aminosulfonyl)phenyl]-2,2-dimethylpropanamide[no description available]low00sulfonamide
2-(benzenesulfonylmethyl)-5-(4-methoxyphenyl)cyclohexane-1,3-dione[no description available]low00sulfonamide
2-[bis(2-methylpropoxy)phosphoryl]-3,3,3-trifluoro-2-[(4-methylphenyl)sulfonylamino]propanoic acid ethyl ester[no description available]low00sulfonamide
N1-{3-[2-(2-pyridyl)ethyl]phenyl}-4-chlorobenzene-1-sulfonamide[no description available]low00sulfonamide
ethyl 1-[4-(4-chlorobenzenesulfonamido)phenyl]-5-(trifluoromethyl)pyrazole-4-carboxylate[no description available]low00ethyl ester;
monochlorobenzenes;
organofluorine compound;
pyrazoles;
sulfonamide
2,3-dichloro-N'-[4-(trifluoromethyl)-2-pyrimidinyl]benzenesulfonohydrazide[no description available]low00sulfonamide
1-(4-ethyl-2-pyridinyl)-3-(4-methylphenyl)sulfonylurea[no description available]low00sulfonamide
1-(3,5-dimethylphenyl)-3-[5-(dimethylsulfamoyl)-2-methylphenyl]urea[no description available]low00sulfonamide
N-{5-[(dimethylamino)sulfonyl]-2-methylphenyl}cyclohexanecarboxamide[no description available]low00sulfonamide
1-tert-butyl-3-[(4-methylphenyl)sulfonylamino]thiourea[no description available]low00sulfonamide
2-[(4-methylphenyl)sulfonylamino]pentanoic acid[no description available]low00sulfonamide
3-methyl-4,7-bis(methylsulfonyl)-3a,5,6,7a-tetrahydro-1H-imidazo[4,5-b]pyrazin-2-one[no description available]low00imidazopyrazine;
sulfonamide;
ureas
N-(3-acetyl-2-methyl-5-benzofuranyl)-N-(4-chloro-3-nitrophenyl)sulfonylacetamide[no description available]low00sulfonamide
2-[(4-chlorophenyl)thio]-N-[4-[(2,4-dimethylphenyl)sulfamoyl]phenyl]propanamide[no description available]low00sulfonamide
4-chloro-N-[2-(4-morpholinyl)cyclohexyl]benzenesulfonamide[no description available]low00sulfonamide
3-(n,n-dimethylsulfonamido)-4-methyl-nitrobenzene[no description available]low00C-nitro compound;
sulfonamide;
toluenes		bone density conservation agent;
EC 3.1.4.53 (3',5'-cyclic-AMP phosphodiesterase) inhibitor;
geroprotector
[4-(benzenesulfonyl)-1-piperazinyl]-(1-piperidinyl)methanone[no description available]low00sulfonamide
N-[3-(2-furanyl)-3-phenylpropyl]-4-methylbenzenesulfonamide[no description available]low00sulfonamide
N-[4-(butylsulfamoyl)phenyl]-2-phenyl-2-(phenylthio)acetamide[no description available]low00sulfonamide
N-[2,6-dimethyl-3-[(4-methyl-1-piperazinyl)sulfonyl]phenyl]-N,4-dimethylbenzenesulfonamide[no description available]low00sulfonamide
2-[4-(1-adamantyl)-N-methylsulfonylanilino]acetic acid[no description available]low00sulfonamide
N-[4-[4-(1-pyrrolidinylsulfonyl)phenyl]-2-thiazolyl]-2,3-dihydro-1,4-benzodioxin-3-carboxamide[no description available]low00sulfonamide
4-(5-(4-methoxyphenyl)-3-phenyl-4,5-dihydro-1h-pyrazol-1-yl)benzenesulfonamide[no description available]low00sulfonamide
4-[oxo-[1-(2,4,6-trimethylphenyl)sulfonyl-4-piperidinyl]methyl]-1-piperazinecarboxylic acid ethyl ester[no description available]low00sulfonamide
N,4-dimethyl-N-{2-oxo-2-[4-(pyridin-2-yl)piperazin-1-yl]ethyl}benzenesulfonamide[no description available]low00sulfonamide
N-[2-(1-phenylethyl)-3,4-dihydro-1H-pyrazino[1,2-a]benzimidazol-8-yl]methanesulfonamide[no description available]low00sulfonamide
N-[1-(4-chlorophenyl)sulfonyl-2-pyrrolidinyl]-4-methyl-1-piperazinecarboxamide[no description available]low00sulfonamide
1-[4-(benzenesulfonyl)-1-piperazinyl]-2-[[1-(2-methylpropyl)-2-benzimidazolyl]thio]ethanone[no description available]low00sulfonamide
N-[4-[(4-hydroxyphenyl)-methylsulfamoyl]phenyl]acetamide[no description available]low00sulfonamide
6-(2,3-dihydro-1,4-benzodioxin-3-ylmethylamino)-N-ethyl-N-phenyl-3-pyridinesulfonamide[no description available]low00pyridines;
sulfonamide
4-chloro-N-(1-propyl-2-benzimidazolyl)-3-(1-pyrrolidinylsulfonyl)benzamide[no description available]low00sulfonamide
2,3-dihydro-1,4-benzodioxin-3-yl-[4-(3,4-dimethylphenyl)sulfonyl-1-piperazinyl]methanone[no description available]low00sulfonamide
N-(1-propyl-2-benzimidazolyl)-3-(1-pyrrolidinylsulfonyl)benzamide[no description available]low00sulfonamide
1-(benzenesulfonyl)-2-benzimidazolamine[no description available]low00sulfonamide
1-(4-nitrophenyl)sulfonyl-2-benzimidazolamine[no description available]low00sulfonamide
sulfatolamide[no description available]low00benzenes;
sulfonamide
e 7010[no description available]low00sulfonamide
deracoxib[no description available]low00organofluorine compound;
pyrazoles;
sulfonamide		cyclooxygenase 2 inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug
diclosulam[no description available]low00sulfonamide
benzene-1-3-disulfonamide[no description available]low00sulfonamide
N-[2-[(2-chloro-1-oxopropyl)hydrazo]-2-oxoethyl]benzenesulfonamide[no description available]low00sulfonamide
3-nitro-N-(pyridin-4-ylmethyl)benzenesulfonamide[no description available]low00sulfonamide
2-[2-[(4-acetamidophenyl)sulfonylamino]-4-thiazolyl]acetic acid ethyl ester[no description available]low00sulfonamide
1-[3-(benzenesulfonyl)-2-(1-piperidinyl)propyl]piperidine[no description available]low00sulfonamide
6-(2-furanyl)-4-[4-(methanesulfonamido)phenyl]-2-oxo-1-cyclohex-3-enecarboxylic acid ethyl ester[no description available]low00sulfonamide
3-(benzenesulfonyl)-N-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]propanamide[no description available]low00sulfonamide
1-(2-furanylmethyl)-3-[[[4-(4-morpholinylsulfonyl)phenyl]-oxomethyl]amino]thiourea[no description available]low00sulfonamide
N1-butan-2-yl-N4-[2-(3,4-dimethoxyphenyl)ethyl]-N4-(thiophen-2-ylmethyl)benzene-1,4-disulfonamide[no description available]low00sulfonamide
1-(4-chlorophenyl)sulfonyl-N'-[oxo-[4-(1-piperidinylsulfonyl)phenyl]methyl]-4-piperidinecarbohydrazide[no description available]low00sulfonamide
N,N-dimethyl-4-[[3-[3-(5-methyl-2-furanyl)-1,2,4-oxadiazol-5-yl]-1-piperidinyl]sulfonyl]benzenesulfonamide[no description available]low00sulfonamide
1-(4-methylphenyl)sulfonyl-3-methylsulfonylimidazolidine[no description available]low00sulfonamide
1-(4-bromophenyl)sulfonyl-4-[(3-methoxyphenyl)methyl]-1,4-diazepane[no description available]low00sulfonamide
2-[[4-[(2,6-dimethyl-4-morpholinyl)sulfonyl]phenyl]-oxomethyl]imino-3,4-dimethyl-5-thiazolecarboxylic acid ethyl ester[no description available]low00sulfonamide
1-(4-chlorophenyl)sulfonyl-N-(2-thiazolyl)-1-cyclopropanecarboxamide[no description available]low00sulfonamide
1-methyl-N-[4-(trifluoromethyl)phenyl]-4-imidazolesulfonamide[no description available]low00sulfonamide
N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-[N-[(3,5-dimethyl-1H-pyrazol-4-yl)sulfonyl]-4-methylanilino]acetamide[no description available]low00sulfonamide
N,N-diethyl-4-[[5-oxo-6-(phenylmethyl)-7H-pyrrolo[3,4-b]pyridin-7-yl]amino]benzenesulfonamide[no description available]low00sulfonamide
N-(1,3-benzodioxol-5-yl)-5-bromo-1-[cyclopropyl(oxo)methyl]-N-ethyl-2,3-dihydroindole-7-sulfonamide[no description available]low00sulfonamide
N-(3,4-dimethylphenyl)-2-[N-[(3,5-dimethyl-1H-pyrazol-4-yl)sulfonyl]-4-methoxyanilino]acetamide[no description available]low00sulfonamide
3,4-dimethoxy-N-[3-(methylthio)phenyl]benzenesulfonamide[no description available]low00sulfonamide
N-[2-(3,4-dimethoxyphenyl)ethyl]-2-[N-[(3,5-dimethyl-4-isoxazolyl)sulfonyl]-4-methylanilino]acetamide[no description available]low00sulfonamide
cyclopentanecarboxylic acid [4-(benzenesulfonyl)-2-tert-butyl-5-methyl-3-pyrazolyl] ester[no description available]low00sulfonamide
4-[[(4-acetamidophenyl)sulfonylamino]methyl]-N-(3-methoxypropyl)benzamide[no description available]low00sulfonamide
4-methyl-N-[2,4,6-trioxo-1-phenyl-5-(trifluoromethyl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]benzenesulfonamide[no description available]low00sulfonamide
6-ethyl-2-[[[4-(4-morpholinylsulfonyl)phenyl]-oxomethyl]amino]-5,7-dihydro-4H-thieno[2,3-c]pyridine-3-carboxamide[no description available]low00sulfonamide
4-(2,3-dihydro-1,4-benzodioxin-3-ylmethylamino)-3-nitrobenzenesulfonamide[no description available]low00benzenes;
sulfonamide
4-[[(4-methylphenyl)sulfonylamino]methyl]-N-[2-[(phenylmethyl)-propan-2-ylamino]ethyl]benzamide[no description available]low00sulfonamide
2-[(5-chloro-1,3-benzothiazol-2-yl)thio]-N-[3-(4-morpholinylsulfonyl)phenyl]propanamide[no description available]low00sulfonamide
N-(6-ethoxy-1,3-benzothiazol-2-yl)-4-methoxy-3-(4-morpholinylsulfonyl)benzamide[no description available]low00sulfonamide
2-ethoxy-3-pyridinecarboxylic acid [2-[2-methyl-5-(4-morpholinylsulfonyl)anilino]-2-oxoethyl] ester[no description available]low00sulfonamide
N-[4-[2-(2-ethyl-1-oxobutyl)-3-phenyl-3,4-dihydropyrazol-5-yl]phenyl]methanesulfonamide[no description available]low00sulfonamide
N-[3-[(2-chlorophenyl)sulfamoyl]-4-methoxyphenyl]-4-oxo-4-thiophen-2-ylbutanamide[no description available]low00sulfonamide
2-(4-methyl-N-(4-methylphenyl)sulfonylanilino)-N-[(1-methyl-4-piperidinylidene)amino]acetamide[no description available]low00sulfonamide
fh535[no description available]low00sulfonamide
1-[4-chloro-3-[(2-methoxyphenyl)sulfamoyl]phenyl]-3-(2-methoxyphenyl)urea[no description available]low00sulfonamide
N-[4-[(3,4-dimethyl-5-isoxazolyl)sulfamoyl]phenyl]-2-(2-pyrimidinylthio)acetamide[no description available]low00sulfonamide
2-[[[5-(dimethylsulfamoyl)-2-methylanilino]-sulfanylidenemethyl]hydrazo]-2-oxoacetamide[no description available]low00sulfonamide
1-(4-butylphenyl)-3-[4-chloro-3-(dimethylsulfamoyl)phenyl]thiourea[no description available]low00sulfonamide
6-methyl-2-[[oxo-[4-(1-pyrrolidinylsulfonyl)phenyl]methyl]amino]-5,7-dihydro-4H-thieno[2,3-c]pyridine-3-carboxamide[no description available]low00sulfonamide
2-(1,3-benzothiazol-2-ylthio)-N-[2-hydroxy-5-(4-morpholinylsulfonyl)phenyl]acetamide[no description available]low00sulfonamide
1-butyl-4,6-dimethyl-3-(2-methylphenyl)sulfonyl-2-pyridinone[no description available]low00sulfonamide
4-(4-methylphenyl)sulfonyl-3-phenyl-2,3-dihydro-1,4-benzoxazine[no description available]low00sulfonamide
N-[3-(4-methyl-1-piperazinyl)-1,4-dioxo-2-naphthalenyl]benzenesulfonamide[no description available]low001,4-naphthoquinones;
piperazines;
sulfonamide
N-(2,2,4-trimethyl-3H-benzofuran-7-yl)benzenesulfonamide[no description available]low00sulfonamide
2-furanyl-[4-(4-propan-2-ylphenyl)sulfonyl-1-piperazinyl]methanone[no description available]low00sulfonamide
5-amino-2-(diethylamino)-N-(2-methoxyphenyl)benzenesulfonamide[no description available]low00benzenes;
sulfonamide
N-(1,3-dimethyl-2-oxo-5-benzimidazolyl)-4-fluoro-3-methylbenzenesulfonamide[no description available]low00sulfonamide
N-[5-(diethylsulfamoyl)-2-methoxyphenyl]-2-[(2,5-dimethylphenyl)thio]acetamide[no description available]low00sulfonamide
2-[(5-anilino-1,3,4-thiadiazol-2-yl)thio]-N-[3-(1-piperidinylsulfonyl)phenyl]acetamide[no description available]low00sulfonamide
4-[(2,6-dimethyl-4-morpholinyl)sulfonyl]-N-[3-(1-imidazolyl)propyl]benzamide[no description available]low00sulfonamide
2-[[3-(3-oxo-1,2-benzothiazol-2-yl)phenyl]sulfonylamino]benzoic acid[no description available]low00sulfonamide
N-[(1,2-dimethyl-5-indolyl)methyl]-4-methoxybenzenesulfonamide[no description available]low00sulfonamide
N,6-dimethyl-2-[[[4-[(2-methyl-1-piperidinyl)sulfonyl]phenyl]-oxomethyl]amino]-5,7-dihydro-4H-thieno[2,3-c]pyridine-3-carboxamide[no description available]low00sulfonamide
N-cyclopropyl-4-methylbenzenesulfonamide[no description available]low00sulfonamide
N-[1-(1H-benzimidazol-2-yl)ethyl]-3-(dimethylsulfamoyl)benzamide[no description available]low00sulfonamide
N-(5-cyclopropyl-1,3,4-oxadiazol-2-yl)-4-[(3-methyl-1-piperidinyl)sulfonyl]benzamide[no description available]low00sulfonamide
N-[4-[(1,2-dimethyl-5-indolyl)methylsulfamoyl]phenyl]acetamide[no description available]low00sulfonamide
2,3-dihydro-1,4-benzodioxin-3-carboxylic acid [2-[2-methyl-5-(4-morpholinylsulfonyl)anilino]-2-oxoethyl] ester[no description available]low00sulfonamide
2-[[5-(4-methylanilino)-1,3,4-thiadiazol-2-yl]thio]-N-[3-(3,4,5,6-tetrahydro-2H-azepin-7-ylsulfamoyl)phenyl]acetamide[no description available]low00sulfonamide
2-(1,3-benzothiazol-2-ylthio)-N-[2-chloro-5-(4-morpholinylsulfonyl)phenyl]acetamide[no description available]low00sulfonamide
1-[3-(dimethylsulfamoyl)phenyl]-3-(2-furanylmethyl)thiourea[no description available]low00sulfonamide
5-nitro-2-furancarboxylic acid [2-oxo-2-[3-(1-piperidinylsulfonyl)anilino]ethyl] ester[no description available]low00sulfonamide
N-[2-(4-methoxyphenyl)ethyl]-2-nitro-4-(1-pyrrolidinylsulfonyl)aniline[no description available]low00benzenes;
sulfonamide
N-(2-ethoxyphenyl)-2,1,3-benzothiadiazole-4-sulfonamide[no description available]low00sulfonamide
N-[3-[2-(4-fluorophenyl)sulfonyl-3-thiophen-2-yl-3,4-dihydropyrazol-5-yl]phenyl]ethanesulfonamide[no description available]low00sulfonamide
N-[5-(2-furanyl)-1,3,4-oxadiazol-2-yl]-4-[(2-methyl-1-piperidinyl)sulfonyl]benzamide[no description available]low00sulfonamide
N-[(3,5-dimethyl-1-piperidinyl)-sulfanylidenemethyl]-2-methyl-5-(4-morpholinylsulfonyl)benzamide[no description available]low00sulfonamide
4-[bis(2-methoxyethyl)sulfamoyl]-N-[5-(methoxymethyl)-1,3,4-oxadiazol-2-yl]benzamide[no description available]low00sulfonamide
2-(benzenesulfonamido)-6-methyl-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylic acid propan-2-yl ester[no description available]low00isopropyl ester;
sulfonamide
2-(3,4-dichlorophenyl)-N-[3-(dimethylsulfamoyl)-4-methylphenyl]acetamide[no description available]low00sulfonamide
N-Cyclopentyl-2-(N-methyl3-chlorobenzenesulfonamido)acetamide[no description available]low00sulfonamideanticoronaviral agent
N-[5-(1-azepanylsulfonyl)-2-chlorophenyl]-2-[(4-methyl-1,2,4-triazol-3-yl)thio]acetamide[no description available]low00sulfonamide
1-(4-methoxyphenyl)-3-[3-(1-piperidinylsulfonyl)phenyl]thiourea[no description available]low00sulfonamide
1-[2-(trifluoromethyl)phenyl]sulfonyl-4-piperidinecarboxylic acid [2-[(4-fluorophenyl)methylamino]-2-oxoethyl] ester[no description available]low00sulfonamide
6-methyl-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylic acid [2-[4-methyl-3-(1-piperidinylsulfonyl)anilino]-2-oxoethyl] ester[no description available]low00sulfonamide
3-[4-(4-butan-2-ylphenyl)sulfonyl-1-piperazinyl]butanoic acid[no description available]low00sulfonamide
3-[(2,6-dimethyl-4-morpholinyl)sulfonyl]-N-(5-methyl-2-thiazolyl)benzamide[no description available]low00sulfonamide
2-[[4-(2-methoxyphenyl)sulfonyl-1-piperazinyl]sulfonyl]benzonitrile[no description available]low00sulfonamide
2-[(5-amino-1,3,4-thiadiazol-2-yl)thio]-N-[3-(diethylsulfamoyl)phenyl]acetamide[no description available]low00sulfonamide
3-[(4-methyl-1-piperazinyl)sulfonyl]-N-(4-phenyl-2-thiazolyl)-N-prop-2-enylbenzamide[no description available]low00sulfonamide
1-(7-methyloctyl)-3-[4-(4-morpholinylsulfonyl)phenyl]thiourea[no description available]low00sulfonamide
5-[(5-bromo-2-ethoxyphenyl)sulfonylamino]-2-chloro-N,N-dimethylbenzenesulfonamide[no description available]low00sulfonamide
2-[[5-[(4-fluorophenoxy)methyl]-4-prop-2-enyl-1,2,4-triazol-3-yl]thio]-N-(3-sulfamoylphenyl)acetamide[no description available]low00sulfonamide
N,N-dimethyl-3-(3-oxo-1,2-benzothiazol-2-yl)benzenesulfonamide[no description available]low00sulfonamide
N-[5-(2-furanyl)-1,3,4-oxadiazol-2-yl]-4-(1-pyrrolidinylsulfonyl)benzamide[no description available]low00sulfonamide
4-(dimethylsulfamoyl)-N-[5-(2-furanyl)-1,3,4-oxadiazol-2-yl]benzamide[no description available]low00sulfonamide
N-methyl-2-[[[4-[methyl(phenyl)sulfamoyl]phenyl]-oxomethyl]amino]-6-propyl-5,7-dihydro-4H-thieno[2,3-c]pyridine-3-carboxamide[no description available]low00sulfonamide
1-[4-chloro-3-(4-morpholinylsulfonyl)phenyl]-3-phenylurea[no description available]low00sulfonamide
dorzolamide[no description available]low00sulfonamide;
thiophenes		antiglaucoma drug;
antihypertensive agent;
EC 4.2.1.1 (carbonic anhydrase) inhibitor
3-(4-methylphenyl)sulfonyl-3-azabicyclo[2.2.1]hept-5-ene-2-carboxylic acid[no description available]low00sulfonamide
N-(3,4-difluorophenyl)-2-[N-[(3,5-dimethyl-4-isoxazolyl)sulfonyl]-4-ethoxyanilino]acetamide[no description available]low00sulfonamide
5-[(4-methoxyphenyl)sulfonylmethyl]-N-(3-methoxypropyl)-2-furancarboxamide[no description available]low00sulfonamide
N-cyclohexyl-N-ethyl-1,3-dimethyl-2,4-dioxo-5-pyrimidinesulfonamide[no description available]low00pyrimidone;
sulfonamide
1,3-dimethyl-2,4-dioxo-N-(4-propan-2-ylphenyl)-5-pyrimidinesulfonamide[no description available]low00sulfonamide
2,5-dimethoxy-N-[[2-(4-methoxyphenyl)-4-thiazolyl]methyl]benzenesulfonamide[no description available]low00sulfonamide
kn 93[no description available]low00monochlorobenzenes;
monomethoxybenzene;
primary alcohol;
sulfonamide;
tertiary amino compound		EC 2.7.11.17 (Ca(2+)/calmodulin-dependent protein kinase) inhibitor;
geroprotector
ro 4-6790[no description available]low00benzenes;
sulfonamide
jnj-7706621[no description available]low00sulfonamide
sultan[no description available]low00sulfonamide
1-[2-furanyl(oxo)methyl]-N-[4-[(3-methyl-1-piperidinyl)sulfonyl]phenyl]-4-piperidinecarboxamide[no description available]low00sulfonamide
sb 269970[no description available]low00sulfonamide
belinostat[no description available]low00hydroxamic acid;
olefinic compound;
sulfonamide		antineoplastic agent;
EC 3.5.1.98 (histone deacetylase) inhibitor
2-bromo-N-(phenylmethyl)benzenesulfonamide[no description available]low00sulfonamide
2-(2,5-dichlorophenyl)sulfonyl-N-methyl-N-[(2-methylphenyl)methyl]ethanamine[no description available]low00sulfonamide
((3z)-n-(3-chlorophenyl)-3-((3,5-dimethyl-4-((4-methylpiperazin-1-yl)carbonyl)-1h-pyrrol-2-yl)methylene)-n-methyl-2-oxo-2,3-dihydro-1h-indole-5-sulfonamide)[no description available]low00sulfonamide
N-[2-methyl-5-(2-thiazolo[5,4-b]pyridinyl)phenyl]-2,3-dihydro-1,4-benzodioxin-6-sulfonamide[no description available]low00sulfonamide
N-[[4-[oxo-[4-(phenylmethyl)-1-piperazinyl]methyl]phenyl]methyl]benzenesulfonamide[no description available]low00sulfonamide
5-chloro-N-[4-(2-thiazolo[5,4-b]pyridinyl)phenyl]-2-thiophenesulfonamide[no description available]low00sulfonamide
4-methyl-N-[[4-[oxo-[4-(phenylmethyl)-1-piperazinyl]methyl]phenyl]methyl]benzenesulfonamide[no description available]low00sulfonamide
4-(5-(4-fluorophenyl)-3-(trifluoromethyl)-1h-pyrazol-1-yl)benzenesulfonamide[no description available]low00organofluorine compound;
pyrazoles;
sulfonamide		cyclooxygenase 2 inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug
bm 567[no description available]low00benzenes;
sulfonamide
mre 269[no description available]low00aromatic amine;
ether;
monocarboxylic acid;
pyrazines;
sulfonamide;
tertiary amino compound		drug metabolite;
orphan drug;
platelet aggregation inhibitor;
prostacyclin receptor agonist;
vasodilator agent
pazopanib[no description available]low00aminopyrimidine;
indazoles;
sulfonamide		angiogenesis modulating agent;
antineoplastic agent;
tyrosine kinase inhibitor;
vascular endothelial growth factor receptor antagonist
azd2858[no description available]low00aromatic amine;
N-methylpiperazine;
pyrazines;
pyridines;
secondary carboxamide;
sulfonamide		antineoplastic agent;
bone density conservation agent;
EC 2.7.11.26 (tau-protein kinase) inhibitor;
Wnt signalling activator
4-(2-((1r)-1-(((4-chlorophenyl)sulfonyl)-2,5-difluoroanilino)ethyl)-5-fluorophenyl)butanoic acid[no description available]low00sulfonamide
apratastat[no description available]low00sulfonamide
N-methyl-N-[2-[[[2-[(2-oxo-1,3-dihydroindol-5-yl)amino]-5-(trifluoromethyl)-4-pyrimidinyl]amino]methyl]phenyl]methanesulfonamide[no description available]low00sulfonamide
florasulam[no description available]low00sulfonamide
(1S,2R)-2-[[4-[(2,4-dimethylphenyl)sulfamoyl]anilino]-oxomethyl]-1-cyclohexanecarboxylic acid[no description available]low00sulfonamide
3-[1-(4-bromophenyl)sulfonyl-3,6-dihydro-2H-pyridin-4-yl]-1,2-dimethylindole[no description available]low00sulfonamide
4-[3-(3-fluorophenyl)-5-phenyl-3,4-dihydropyrazol-2-yl]benzenesulfonamide[no description available]low00sulfonamide
2-[[[4-[(2,6-dimethyl-4-morpholinyl)sulfonyl]phenyl]-oxomethyl]amino]-3-thiophenecarboxamide[no description available]low00sulfonamide
4-[3-(4-methylphenyl)-5-phenyl-3,4-dihydropyrazol-2-yl]benzenesulfonamide[no description available]low00sulfonamide
N-[5-[ethyl(phenyl)sulfamoyl]-1,3,4-thiadiazol-2-yl]-2-furancarboxamide[no description available]low00sulfonamide
calcium crimson[no description available]low00ammonium betaine;
sulfonamide		fluorochrome
4-methoxy-N-[[1-[(3-methyl-2-thiophenyl)-oxomethyl]-3-piperidinyl]methyl]benzenesulfonamide[no description available]low00sulfonamide
N'-[[3-(4-methylphenyl)sulfonyl-2-oxazolidinyl]methyl]-N-[2-(4-sulfamoylphenyl)ethyl]oxamide[no description available]low00sulfonamide
tg101209[no description available]low00N-alkylpiperazine;
N-arylpiperazine;
pyrimidines;
secondary amino compound;
sulfonamide		antineoplastic agent;
apoptosis inducer;
EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor
fedratinib[no description available]low00sulfonamide
WAY-316606[no description available]low00(trifluoromethyl)benzenes;
piperidines;
secondary amino compound;
sulfonamide;
sulfone		secreted frizzled-related protein 1 inhibitor
azd5438[no description available]low00sulfonamide
gdc 0941[no description available]low00indazoles;
morpholines;
piperazines;
sulfonamide;
thienopyrimidine		EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor
4-methoxy-N-[[4-[oxo-[4-(phenylmethyl)-1-piperazinyl]methyl]phenyl]methyl]benzenesulfonamide[no description available]low00sulfonamide
N-[5-[methyl-(3-methylphenyl)sulfamoyl]-1,3,4-thiadiazol-2-yl]-2-furancarboxamide[no description available]low00sulfonamide
gsk 1016790a[no description available]low001-benzothiophenes;
aromatic primary alcohol;
dichlorobenzene;
N-acylpiperazine;
sulfonamide;
tertiary carboxamide		TRPV4 agonist
plx 4720[no description available]low00aromatic ketone;
difluorobenzene;
organochlorine compound;
pyrrolopyridine;
sulfonamide		antineoplastic agent;
B-Raf inhibitor
gsk 2126458[no description available]low00aromatic ether;
difluorobenzene;
pyridazines;
pyridines;
quinolines;
sulfonamide		anticoronaviral agent;
antineoplastic agent;
autophagy inducer;
EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor;
mTOR inhibitor;
radiosensitizing agent
1-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-4-(4-fluorophenyl)sulfonylpiperazine[no description available]low00sulfonamide
(2R)-4-(2,6-difluorophenyl)sulfonyl-1-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-2-methylpiperazine[no description available]low00sulfonamide
[4-(2,6-difluorophenyl)sulfonyl-1-piperazinyl]-(2,3-dihydro-1,4-benzodioxin-6-yl)methanone[no description available]low00sulfonamide
(2R)-1-(2,6-difluorophenyl)sulfonyl-4-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-2-methylpiperazine[no description available]low00sulfonamide
(2S)-4-(2,6-difluorophenyl)sulfonyl-1-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-2-methylpiperazine[no description available]low00sulfonamide
(2S)-1-(2,6-difluorophenyl)sulfonyl-4-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-2-methylpiperazine[no description available]low00sulfonamide
1-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-4-(2-pyridinylsulfonyl)piperazine[no description available]low00pyridines;
sulfonamide
N-[1-(2,6-difluorophenyl)sulfonyl-4-piperidinyl]-2,3-dihydro-1,4-benzodioxin-6-sulfonamide[no description available]low00sulfonamide
1-(2,6-difluorophenyl)sulfonyl-4-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-1,4-diazepane[no description available]low00sulfonamide
N-[4-[(2,6-difluorophenyl)sulfonylamino]cyclohexyl]-2,3-dihydro-1,4-benzodioxin-6-sulfonamide[no description available]low00sulfonamide
1-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-4-[3-(trifluoromethyl)phenyl]sulfonylpiperazine[no description available]low00sulfonamide
N-[[1-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-3-azetidinyl]methyl]-2,6-difluorobenzenesulfonamide[no description available]low00sulfonamide
N-[[1-(2,6-difluorophenyl)sulfonyl-3-azetidinyl]methyl]-2,3-dihydro-1,4-benzodioxin-6-sulfonamide[no description available]low00sulfonamide
N-[1-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-3-pyrrolidinyl]-2,6-difluorobenzenesulfonamide[no description available]low00sulfonamide
N-[3-[(2,6-difluorophenyl)sulfonylamino]propyl]-2,3-dihydro-1,4-benzodioxin-6-sulfonamide[no description available]low00sulfonamide
N-[5-[(2,6-difluorophenyl)sulfonylamino]pentyl]-2,3-dihydro-1,4-benzodioxin-6-sulfonamide[no description available]low00sulfonamide
N-[6-[(2,6-difluorophenyl)sulfonylamino]hexyl]-2,3-dihydro-1,4-benzodioxin-6-sulfonamide[no description available]low00sulfonamide
N-[2-[(2,6-difluorophenyl)sulfonylamino]ethyl]-2,3-dihydro-1,4-benzodioxin-6-sulfonamide[no description available]low00sulfonamide
N-[1-(2,6-difluorophenyl)sulfonyl-3-pyrrolidinyl]-2,3-dihydro-1,4-benzodioxin-6-sulfonamide[no description available]low00sulfonamide
N-[4-[(2,6-difluorophenyl)sulfonylamino]butyl]-2,3-dihydro-1,4-benzodioxin-6-sulfonamide[no description available]low00sulfonamide
1-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-4-(2-nitrophenyl)sulfonylpiperazine[no description available]low00sulfonamide
4-[4-(4-methylphenyl)sulfonyl-1-piperazinyl]-2-thiophen-2-ylquinazoline[no description available]low00sulfonamide
plx4032[no description available]low00aromatic ketone;
difluorobenzene;
monochlorobenzenes;
pyrrolopyridine;
sulfonamide		antineoplastic agent;
B-Raf inhibitor
N-[[4-[(2,6-difluorophenyl)sulfonylamino]cyclohexyl]methyl]-2,3-dihydro-1,4-benzodioxin-6-sulfonamide[no description available]low00sulfonamide
1-(3-chlorophenyl)sulfonyl-4-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)piperazine[no description available]low00sulfonamide
1-(3-bromophenyl)sulfonyl-4-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)piperazine[no description available]low00sulfonamide
(1S,4S)-2-(2,6-difluorophenyl)sulfonyl-5-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-2,5-diazabicyclo[2.2.1]heptane[no description available]low00sulfonamide
1-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-4-(2,4,6-trifluorophenyl)sulfonylpiperazine[no description available]low00sulfonamide
N-(1-cyano-3-pyrrolidinyl)-3-methoxybenzenesulfonamide[no description available]low00sulfonamide
N-(1-cyano-3-pyrrolidinyl)-4-(trifluoromethyl)benzenesulfonamide[no description available]low00sulfonamide
N-(1-cyano-4-piperidinyl)-4-(trifluoromethyl)benzenesulfonamide[no description available]low00sulfonamide
4-[3-(3-methylphenyl)-5-phenyl-3,4-dihydropyrazol-2-yl]benzenesulfonamide[no description available]low00sulfonamide
4-[3-(3-bromophenyl)-5-phenyl-3,4-dihydropyrazol-2-yl]benzenesulfonamide[no description available]low00sulfonamide
1-cyclohexyl-3-[(2S,3S)-5-[(2R)-1-hydroxypropan-2-yl]-2-[[(4-methoxyphenyl)sulfonyl-methylamino]methyl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-10-yl]urea[no description available]low00sulfonamide
N-[(2S,3S)-2-[[(3,4-dichlorophenyl)methyl-methylamino]methyl]-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-10-yl]-2-thiophenesulfonamide[no description available]low00sulfonamide
N-[(2S,3S)-2-[[(4-fluorophenyl)sulfonyl-methylamino]methyl]-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-8-yl]cyclopropanecarboxamide[no description available]low00sulfonamide
N-[(2S,3S)-2-[[cyclopropylmethyl(methyl)amino]methyl]-5-[(2S)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-2,3,4,7-tetrahydro-1,5-benzoxazonin-9-yl]methanesulfonamide[no description available]low00sulfonamide
N-[[(2S,3S)-10-(dimethylamino)-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-2-yl]methyl]-4-methoxy-N-methylbenzenesulfonamide[no description available]low00sulfonamide
N-[(2R,3S)-2-[[(4-chlorophenyl)sulfonyl-methylamino]methyl]-5-[(2S)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-2,3,4,7-tetrahydro-1,5-benzoxazonin-9-yl]-4,4,4-trifluorobutanamide[no description available]low00sulfonamide
3-cyclohexyl-1-[[(2S,3S)-8-[(4-fluorophenyl)sulfonylamino]-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-2-yl]methyl]-1-methylurea[no description available]low00sulfonamide
3-cyclohexyl-1-[[(2R,3R)-10-[(4-fluorophenyl)sulfonylamino]-5-[(2S)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-2-yl]methyl]-1-methylurea[no description available]low00sulfonamide
4-chloro-N-[(2R,3R)-5-[(2S)-1-hydroxypropan-2-yl]-3-methyl-2-[[methyl(pyridin-4-ylmethyl)amino]methyl]-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-8-yl]benzenesulfonamide[no description available]low00sulfonamide
1-[(2S,3S)-2-[[benzenesulfonyl(methyl)amino]methyl]-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-8-yl]-3-[4-(trifluoromethyl)phenyl]urea[no description available]low00sulfonamide
N-[(2S,3S)-2-[[cyclohexylmethyl(methyl)amino]methyl]-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-10-yl]-4-methoxybenzenesulfonamide[no description available]low00sulfonamide
N-[(2S,3S)-2-[[benzenesulfonyl(methyl)amino]methyl]-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-10-yl]-4-pyridinecarboxamide[no description available]low00sulfonamide
4-fluoro-N-[(2S,3S)-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-2-(methylaminomethyl)-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-10-yl]benzenesulfonamide[no description available]low00sulfonamide
N-[(2R,3R)-2-[[(4-fluorophenyl)sulfonyl-methylamino]methyl]-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-8-yl]-2-(1-methyl-3-indolyl)acetamide[no description available]low00sulfonamide
1-[(2R,3R)-2-[[benzenesulfonyl(methyl)amino]methyl]-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-8-yl]-3-[4-(trifluoromethyl)phenyl]urea[no description available]low00sulfonamide
baricitinib[no description available]low00azetidines;
nitrile;
pyrazoles;
pyrrolopyrimidine;
sulfonamide		anti-inflammatory agent;
antirheumatic drug;
antiviral agent;
EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor;
immunosuppressive agent
1-(4-methoxyphenyl)sulfonyl-2-benzimidazolamine[no description available]low00sulfonamide
5,6-dimethyl-1-(4-methylphenyl)sulfonyl-2-benzimidazolamine[no description available]low00sulfonamide
N-[(2S,3S)-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-2-(methylaminomethyl)-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-10-yl]-4-methoxybenzenesulfonamide[no description available]low00sulfonamide
dabrafenib[no description available]low001,3-thiazoles;
aminopyrimidine;
organofluorine compound;
sulfonamide		anticoronaviral agent;
antineoplastic agent;
B-Raf inhibitor
3-[[4-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-1,4-diazepan-1-yl]sulfonyl]aniline[no description available]low00benzenes;
sulfonamide
4-[[(4-ethylphenyl)sulfonylamino]methyl]-N-[2-[(phenylmethyl)-propan-2-ylamino]ethyl]benzamide[no description available]low00sulfonamide
EG00229[no description available]low00benzothiadiazole;
dicarboxylic acid monoamide;
L-arginine derivative;
secondary carboxamide;
sulfonamide;
thiophenes		angiogenesis inhibitor;
antineoplastic agent;
neuropilin receptor antagonist
gsk0660[no description available]low00sulfonamide
xl765[no description available]low00aromatic amine;
aromatic ether;
benzamides;
quinoxaline derivative;
sulfonamide		antineoplastic agent;
EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor;
mTOR inhibitor
N-(3-chlorophenyl)-3-[[3,5-dimethyl-4-[(4-methyl-1-piperazinyl)-oxomethyl]-1H-pyrrol-2-yl]methylidene]-N-methyl-2-oxo-1H-indole-5-sulfonamide[no description available]low00sulfonamide
tipranavir[no description available]low00sulfonamideantiviral drug;
HIV protease inhibitor
abt-333[no description available]low00aromatic ether;
naphthalenes;
pyrimidone;
sulfonamide		antiviral drug;
nonnucleoside hepatitis C virus polymerase inhibitor
pik 75[no description available]low00sulfonamide
vx-970[no description available]low00sulfonamide
pf-543[no description available]low00sulfonamide
ML355[no description available]low00benzothiazoles;
monomethoxybenzene;
phenols;
secondary amino compound;
substituted aniline;
sulfonamide		EC 1.13.11.31 (arachidonate 12-lipoxygenase) inhibitor;
platelet aggregation inhibitor
sr9243[no description available]low00bromobenzenes;
sulfonamide;
sulfone		antineoplastic agent;
apoptosis inducer;
liver X receptor inverse agonist
sildenafil[no description available]low00piperazines;
pyrazolopyrimidine;
sulfonamide		EC 3.1.4.35 (3',5'-cyclic-GMP phosphodiesterase) inhibitor;
vasodilator agent
da 8159[no description available]low00sulfonamide
3-[[2-[4-(4-chlorophenyl)sulfonyl-1-piperazinyl]-2-oxoethyl]thio]-6-methyl-2H-1,2,4-triazin-5-one[no description available]low00sulfonamide
N-tert-butyl-3-(3-tert-butyl-1-methyl-7-oxo-4H-pyrazolo[4,3-d]pyrimidin-5-yl)-4-ethoxybenzenesulfonamide[no description available]low00sulfonamide
N-[4-[2-[3-(dimethylsulfamoyl)anilino]-6H-1,3,4-thiadiazin-5-yl]phenyl]acetamide[no description available]low00sulfonamide
N-[2-[(4-chlorophenyl)methylthio]-4-oxo-1H-pyrimidin-6-yl]benzenesulfonamide[no description available]low00sulfonamide
N-[2-[(2-chlorophenyl)methylthio]-4-oxo-1H-pyrimidin-6-yl]-4-methylbenzenesulfonamide[no description available]low00sulfonamide
N-(4-methoxyphenyl)-2-[[6-[(4-methylphenyl)sulfonylamino]-4-oxo-1H-pyrimidin-2-yl]thio]acetamide[no description available]low00sulfonamide
mirodenafil[no description available]low00aromatic ether;
N-alkylpiperazine;
primary alcohol;
pyrrolopyrimidine;
sulfonamide		EC 3.1.4.35 (3',5'-cyclic-GMP phosphodiesterase) inhibitor;
vasodilator agent
da-8164[no description available]low00sulfonamide
ConditionIndicatedRelationship StrengthStudiesTrials
Acquired Form of Epidermolysis Bullosa0low10
Arthritis, Degenerative0low10
Arthroses0low10
Arthrosis0low10
Body Weight0low10
Cardiac Hypertrophy0low10
Cardiomegaly0low10
Cardiovascular Stroke0low10
Congenital Zika Syndrome0low10
Congenital Zika Virus Infection0low10
Diabetic Cardiomyopathies0low10
Disease Models, Animal0low60
Endotoxin Shock0low10
Enlarged Heart0low10
Epidermolysis Bullosa Acquisita0low10
Epidermolysis Bullosa, Acquired0low10
Fever, Zika0low10
Genetic Predisposition0low10
Genetic Predisposition to Disease0low10
Genetic Susceptibility0low10
Heart Attack0low10
Heart Enlargement0low10
Heart Hypertrophy0low10
Inflammation0low10
Innate Inflammatory Response0low10
Myocardial Infarct0low10
Myocardial Infarction0low10
Osteoarthritis0low10
Osteoarthrosis0low10
Osteoarthrosis Deformans0low10
Predisposition, Genetic0low10
Septic Shock0low10
Shock, Endotoxic0low10
Shock, Septic0low10
Shock, Toxic0low10
Susceptibility, Genetic0low10
Toxic Shock0low10
Toxic Shock Syndrome0low10
Zika Fever0low10
Zika Virus Disease0low10
Zika Virus Infection0low10
ZikV Infection0low10

Research Highlights

Bioavailability (1)

ArticleYear
A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
Molecular pharmacology, Volume: 96, Issue: 5		2019
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]