| Assay ID | Title | Year | Journal | Article |
|---|
| AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1
| High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID1745845 | Primary qHTS for Inhibitors of ATXN expression | | | |
| AID1347082 | qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lassa (LASV) Arenavirus: LASV Primary Screen - GLuc reporter signal | 2020 | Antiviral research, 01, Volume: 173 | A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity. |
| AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1
| High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID1347086 | qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lymphocytic Choriomeningitis Arenaviruses (LCMV): LCMV Primary Screen - GLuc reporter signal | 2020 | Antiviral research, 01, Volume: 173 | A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity. |
| AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1
| High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID1347083 | qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lassa (LASV) Arenavirus: Viability assay - alamar blue signal for LASV Primary Screen | 2020 | Antiviral research, 01, Volume: 173 | A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity. |
| AID651635 | Viability Counterscreen for Primary qHTS for Inhibitors of ATXN expression | | | |
| AID274384 | Displacement of [3H]E2 from human recombinant ERbeta LBD by SPA | 2006 | Journal of medicinal chemistry, Dec-14, Volume: 49, Issue:25
| Subtle side-chain modifications of the hop phytoestrogen 8-prenylnaringenin result in distinct agonist/antagonist activity profiles for estrogen receptors alpha and beta. |
| AID376640 | Selectivity index, ratio of CC50 for mouse RAW264.7 cells to IC50 for nitric oxide production in mouse RAW264.7 cells | 2006 | Journal of natural products, Apr, Volume: 69, Issue:4
| Prenylated flavonoids from the heartwood of Artocarpus communis with inhibitory activity on lipopolysaccharide-induced nitric oxide production. |
| AID274386 | Agonist activity on ERalpha-mediated transcription of ERE-luciferase reporter gene in human Huh7 cells | 2006 | Journal of medicinal chemistry, Dec-14, Volume: 49, Issue:25
| Subtle side-chain modifications of the hop phytoestrogen 8-prenylnaringenin result in distinct agonist/antagonist activity profiles for estrogen receptors alpha and beta. |
| AID600289 | Neuroprotective activity against oxygen-glucose deprivation-induced cell injury in rat PC12 cells assessed as cell viability at 1 uM | 2009 | Bioorganic & medicinal chemistry letters, Jun-15, Volume: 19, Issue:12
| Synthesis, biological evaluation of prenylflavonoids as vasorelaxant and neuroprotective agents. |
| AID274383 | Displacement of [3H]E2 from human recombinant ERalpha LBD by SPA | 2006 | Journal of medicinal chemistry, Dec-14, Volume: 49, Issue:25
| Subtle side-chain modifications of the hop phytoestrogen 8-prenylnaringenin result in distinct agonist/antagonist activity profiles for estrogen receptors alpha and beta. |
| AID600292 | Vasorelaxant activity in rat aortic ring assessed as inhibition of phenylephrine-induced contraction relative to control | 2009 | Bioorganic & medicinal chemistry letters, Jun-15, Volume: 19, Issue:12
| Synthesis, biological evaluation of prenylflavonoids as vasorelaxant and neuroprotective agents. |
| AID1242901 | Inhibition of porcine pancreatic lipase pre-incubated for 15 mins before p-nitrophenylbutyrate substrate addition by microplate reader based method | 2015 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 25, Issue:17
| Benzylated and prenylated flavonoids from the root barks of Cudrania tricuspidata with pancreatic lipase inhibitory activity. |
| AID356327 | Antifungal activity against Aspergillus fumigatus IFM 41374 after 48 to 96 hrs by broth microdilution method | 2003 | Journal of natural products, Aug, Volume: 66, Issue:8
| Antifungal agents from the roots of Cudrania cochinchinensis against Candida, Cryptococcus, and Aspergillus species. |
| AID430989 | Cytotoxicity against human PANC1 cells in nutrient-deprived condition assessed as 50% cell death after 24 hrs by WST8 assay | 2009 | Journal of natural products, Jul, Volume: 72, Issue:7
| Chemical constituents of propolis from Myanmar and their preferential cytotoxicity against a human pancreatic cancer cell line. |
| AID376638 | Inhibition of LPS-induced nitric oxide production in mouse RAW264.7 cells assessed as nitrite accumulation after 20 hrs | 2006 | Journal of natural products, Apr, Volume: 69, Issue:4
| Prenylated flavonoids from the heartwood of Artocarpus communis with inhibitory activity on lipopolysaccharide-induced nitric oxide production. |
| AID274387 | Agonist activity on ERbeta-mediated transcription of ERE-luciferase reporter gene in human Huh7 cells | 2006 | Journal of medicinal chemistry, Dec-14, Volume: 49, Issue:25
| Subtle side-chain modifications of the hop phytoestrogen 8-prenylnaringenin result in distinct agonist/antagonist activity profiles for estrogen receptors alpha and beta. |
| AID358550 | Selectivity ratio CC50 for HGF to CC50 for human HSC-2 cells | 2001 | Journal of natural products, Jan, Volume: 64, Issue:1
| Benzophenones and xanthones with isoprenoid groups from Cudrania cochinchinensis. |
| AID356328 | Antifungal activity against Aspergillus fumigatus IFM 41236 after 48 to 96 hrs by broth microdilution method | 2003 | Journal of natural products, Aug, Volume: 66, Issue:8
| Antifungal agents from the roots of Cudrania cochinchinensis against Candida, Cryptococcus, and Aspergillus species. |
| AID1254735 | Terminal half life in human at 60 mg, po by LC-MS/MS method | 2015 | Journal of medicinal chemistry, Nov-12, Volume: 58, Issue:21
| Development of Safe and Effective Botanical Dietary Supplements. |
| AID356322 | Antifungal activity against Candida albicans ATCC 90028 after 48 to 96 hrs by broth microdilution method | 2003 | Journal of natural products, Aug, Volume: 66, Issue:8
| Antifungal agents from the roots of Cudrania cochinchinensis against Candida, Cryptococcus, and Aspergillus species. |
| AID376639 | Cytotoxicity against mouse RAW264.7 cells by MTT assay | 2006 | Journal of natural products, Apr, Volume: 69, Issue:4
| Prenylated flavonoids from the heartwood of Artocarpus communis with inhibitory activity on lipopolysaccharide-induced nitric oxide production. |
| AID600288 | Vasorelaxant activity in rat aortic ring assessed as inhibition of phenylephrine-induced contraction | 2009 | Bioorganic & medicinal chemistry letters, Jun-15, Volume: 19, Issue:12
| Synthesis, biological evaluation of prenylflavonoids as vasorelaxant and neuroprotective agents. |
| AID430984 | Cytotoxicity against human PANC1 cells in nutrient-deprived condition assessed as 100% cell death after 24 hrs by WST8 assay | 2009 | Journal of natural products, Jul, Volume: 72, Issue:7
| Chemical constituents of propolis from Myanmar and their preferential cytotoxicity against a human pancreatic cancer cell line. |
| AID356324 | Antifungal activity against Candida glabrata ATCC 90030 after 48 to 96 hrs by broth microdilution method | 2003 | Journal of natural products, Aug, Volume: 66, Issue:8
| Antifungal agents from the roots of Cudrania cochinchinensis against Candida, Cryptococcus, and Aspergillus species. |
| AID274385 | Selectivity for recombinant human ERbeta over ERalpha | 2006 | Journal of medicinal chemistry, Dec-14, Volume: 49, Issue:25
| Subtle side-chain modifications of the hop phytoestrogen 8-prenylnaringenin result in distinct agonist/antagonist activity profiles for estrogen receptors alpha and beta. |
| AID1087279 | Antiproliferative activity against Homo sapiens (human) MCF7 cells after 72 hr by SRB assay | 2012 | Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents, Dec, Volume: 21, Issue:12
| Antiproliferative activity and synthesis of 8-prenylnaringenin derivatives by demethylation of 7-O- and 4'-O-substituted isoxanthohumols. |
| AID358549 | Cytotoxicity against HGF cells | 2001 | Journal of natural products, Jan, Volume: 64, Issue:1
| Benzophenones and xanthones with isoprenoid groups from Cudrania cochinchinensis. |
| AID1238084 | Cytotoxicity against mouse RAW264.7 cells assessed as cell viability at IC50 by MTT assay | 2015 | Bioorganic & medicinal chemistry letters, Aug-15, Volume: 25, Issue:16
| Chemical constituents isolated from the Mongolian medicinal plant Sophora alopecuroides L. and their inhibitory effects on LPS-induced nitric oxide production in RAW 264.7 macrophages. |
| AID1087277 | Antiproliferative activity against Homo sapiens (human) CCRF-CEM cells after 72 hr by MTT assay | 2012 | Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents, Dec, Volume: 21, Issue:12
| Antiproliferative activity and synthesis of 8-prenylnaringenin derivatives by demethylation of 7-O- and 4'-O-substituted isoxanthohumols. |
| AID1242902 | Inhibition of porcine pancreatic lipase at 100 ug/ml pre-incubated for 15 mins before p-nitrophenylbutyrate substrate addition by microplate reader based method | 2015 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 25, Issue:17
| Benzylated and prenylated flavonoids from the root barks of Cudrania tricuspidata with pancreatic lipase inhibitory activity. |
| AID1238082 | Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-stimulated nitric oxide production after 24 hrs by Griess method | 2015 | Bioorganic & medicinal chemistry letters, Aug-15, Volume: 25, Issue:16
| Chemical constituents isolated from the Mongolian medicinal plant Sophora alopecuroides L. and their inhibitory effects on LPS-induced nitric oxide production in RAW 264.7 macrophages. |
| AID1087278 | Antiproliferative activity against Homo sapiens (human) HT-29 cells after 72 hr by SRB assay | 2012 | Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents, Dec, Volume: 21, Issue:12
| Antiproliferative activity and synthesis of 8-prenylnaringenin derivatives by demethylation of 7-O- and 4'-O-substituted isoxanthohumols. |
| AID362785 | Inhibition of human recombinant PDE5A1 expressed in COS7 cells | 2008 | Journal of natural products, Sep, Volume: 71, Issue:9
| Potent inhibition of human phosphodiesterase-5 by icariin derivatives. |
| AID356329 | Antifungal activity against Aspergillus nidulans IFM 5396 after 48 to 96 hrs by broth microdilution method | 2003 | Journal of natural products, Aug, Volume: 66, Issue:8
| Antifungal agents from the roots of Cudrania cochinchinensis against Candida, Cryptococcus, and Aspergillus species. |
| AID356326 | Antifungal activity against Cryptococcus neoformans ATCC 90112 after 48 to 96 hrs by broth microdilution method | 2003 | Journal of natural products, Aug, Volume: 66, Issue:8
| Antifungal agents from the roots of Cudrania cochinchinensis against Candida, Cryptococcus, and Aspergillus species. |
| AID356323 | Antifungal activity against Candida parapsilosis ATCC 22019 after 48 to 96 hrs by broth microdilution method | 2003 | Journal of natural products, Aug, Volume: 66, Issue:8
| Antifungal agents from the roots of Cudrania cochinchinensis against Candida, Cryptococcus, and Aspergillus species. |
| AID358548 | Cytotoxicity against human HSC2 cells | 2001 | Journal of natural products, Jan, Volume: 64, Issue:1
| Benzophenones and xanthones with isoprenoid groups from Cudrania cochinchinensis. |
| AID356325 | Antifungal activity against Candida krusei ATCC 6258 after 48 to 96 hrs by broth microdilution method | 2003 | Journal of natural products, Aug, Volume: 66, Issue:8
| Antifungal agents from the roots of Cudrania cochinchinensis against Candida, Cryptococcus, and Aspergillus species. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |