| Assay ID | Title | Year | Journal | Article |
|---|
| AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1
| High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID651635 | Viability Counterscreen for Primary qHTS for Inhibitors of ATXN expression | | | |
| AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1
| High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1
| High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID1745845 | Primary qHTS for Inhibitors of ATXN expression | | | |
| AID398787 | Antibacterial activity against Mycobacterium smegmatis ATCC 607 by agar-dilution streak method | | | |
| AID1453624 | Inhibition of recombinant human PTP1B using p-nitrophenyl phosphate as substrate after 30 mins | 2017 | Bioorganic & medicinal chemistry, 07-15, Volume: 25, Issue:14
| Screening for bioactive natural products from a 67-compound library of Glycyrrhiza inflata. |
| AID1175337 | Inhibition of A23187-induced IL-6 production in human HMC1 cells incubated for 30 mins prior to A23187 challenge measured after 24 hrs by ELISA | 2014 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 24, Issue:24
| Flavonoids and arylbenzofurans from the rhizomes and roots of Sophora tonkinensis with IL-6 production inhibitory activity. |
| AID1453616 | Growth inhibition of human HepG2 cells at 10 uM after 24 hrs by MTS assay relative to control | 2017 | Bioorganic & medicinal chemistry, 07-15, Volume: 25, Issue:14
| Screening for bioactive natural products from a 67-compound library of Glycyrrhiza inflata. |
| AID1453621 | Inhibition of LPS-induced NF-kappaB transcription (unknown origin) expressed in human SW480 cells at 10 uM by luciferase reporter gene assay | 2017 | Bioorganic & medicinal chemistry, 07-15, Volume: 25, Issue:14
| Screening for bioactive natural products from a 67-compound library of Glycyrrhiza inflata. |
| AID1432767 | Enhancement of GLUT4 translocation at plasma membrane of rat L6 cells expressing pIRAP-mOrange at 10 uM after 30 mins by fluorescence assay relative to control | 2017 | Bioorganic & medicinal chemistry letters, 03-15, Volume: 27, Issue:6
| Chemical constituents from Sophora tonkinensis and their glucose transporter 4 translocation activities. |
| AID1484039 | Activation of Nrf2 (unknown origin) expressed in human HepG2 cells at 10 uM after 6 hrs by ARE-driven luciferase reporter gene assay relative to control | 2017 | Journal of natural products, 02-24, Volume: 80, Issue:2
| Glycybridins A-K, Bioactive Phenolic Compounds from Glycyrrhiza glabra. |
| AID775571 | Inhibition of PTP1B (unknown origin) using p-nitrophenyl phosphate as substrate | 2013 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 23, Issue:21
| Evaluation of licorice flavonoids as protein tyrosine phosphatase 1B inhibitors. |
| AID668112 | Hypnotic activity in po dosed fasted C57BL/6N mouse assessed as decrease in latency of pentobarbital-induced sleep administered 45 mins prior to pentobarbital-induction by polysomnographic analysis | 2012 | Bioorganic & medicinal chemistry, Jun-01, Volume: 20, Issue:11
| Hypnotic effects and GABAergic mechanism of licorice (Glycyrrhiza glabra) ethanol extract and its major flavonoid constituent glabrol. |
| AID1453612 | Cytotoxicity against human SW480 cells assessed as reduction in cell viability after 24 hrs by MTS assay | 2017 | Bioorganic & medicinal chemistry, 07-15, Volume: 25, Issue:14
| Screening for bioactive natural products from a 67-compound library of Glycyrrhiza inflata. |
| AID668114 | Hypnotic activity in fasted C57BL/6N mouse assessed as increase in latency of pentobarbital-induced sleep at 50 mg/kg, po administered 45 mins prior to pentobarbital-induction by polysomnographic analysis | 2012 | Bioorganic & medicinal chemistry, Jun-01, Volume: 20, Issue:11
| Hypnotic effects and GABAergic mechanism of licorice (Glycyrrhiza glabra) ethanol extract and its major flavonoid constituent glabrol. |
| AID668117 | Hypnotic activity in fasted C57BL/6N mouse assessed as decrease in latency of pentobarbital-induced sleep at 50 mg/kg, po administered 45 mins prior to pentobarbital-induction coadministered with flumazenil by polysomnographic analysis | 2012 | Bioorganic & medicinal chemistry, Jun-01, Volume: 20, Issue:11
| Hypnotic effects and GABAergic mechanism of licorice (Glycyrrhiza glabra) ethanol extract and its major flavonoid constituent glabrol. |
| AID1484034 | Inhibition of tyrosinase (unknown origin) using L-tyrosine as substrate at 10 uM preincubated for 15 mins followed by substrate addition relative to control | 2017 | Journal of natural products, 02-24, Volume: 80, Issue:2
| Glycybridins A-K, Bioactive Phenolic Compounds from Glycyrrhiza glabra. |
| AID1453619 | Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO production at 10 uM after 24 hrs by Griess reagent based assay relative to control | 2017 | Bioorganic & medicinal chemistry, 07-15, Volume: 25, Issue:14
| Screening for bioactive natural products from a 67-compound library of Glycyrrhiza inflata. |
| AID1073044 | Inhibition of Influenza A virus (A/Puerto Rico/8/1934(H1N1)) neuraminidase by chemiluminescence based assay | 2014 | Journal of natural products, Mar-28, Volume: 77, Issue:3
| Computer-guided approach to access the anti-influenza activity of licorice constituents. |
| AID1453614 | Growth inhibition of human MCF7 cells at 10 uM after 24 hrs by MTS assay relative to control | 2017 | Bioorganic & medicinal chemistry, 07-15, Volume: 25, Issue:14
| Screening for bioactive natural products from a 67-compound library of Glycyrrhiza inflata. |
| AID1073036 | Induction of fluorescence at 100 uM relative to 4-methylumbelliferone | 2014 | Journal of natural products, Mar-28, Volume: 77, Issue:3
| Computer-guided approach to access the anti-influenza activity of licorice constituents. |
| AID1484047 | Antiproliferative activity against human MCF7 cells at 10 uM after 24 hrs by MTS assay relative to control | 2017 | Journal of natural products, 02-24, Volume: 80, Issue:2
| Glycybridins A-K, Bioactive Phenolic Compounds from Glycyrrhiza glabra. |
| AID1484038 | Inhibition of recombinant human PTP1B using pNPP as substrate after 30 mins | 2017 | Journal of natural products, 02-24, Volume: 80, Issue:2
| Glycybridins A-K, Bioactive Phenolic Compounds from Glycyrrhiza glabra. |
| AID398781 | Antibacterial activity against Escherichia coli ATCC 9637 at 100 mcg/ml by agar-dilution streak method | | | |
| AID1453615 | Growth inhibition of human SW480 cells at 10 uM after 24 hrs by MTS assay relative to control | 2017 | Bioorganic & medicinal chemistry, 07-15, Volume: 25, Issue:14
| Screening for bioactive natural products from a 67-compound library of Glycyrrhiza inflata. |
| AID1073034 | Inhibition of Clostridium perfringens neuraminidase by fluorescence based assay | 2014 | Journal of natural products, Mar-28, Volume: 77, Issue:3
| Computer-guided approach to access the anti-influenza activity of licorice constituents. |
| AID1073043 | Inhibition of oseltamivir-resistant Influenza A virus H1N1 B/55/08 neuraminidase by chemiluminescence based assay | 2014 | Journal of natural products, Mar-28, Volume: 77, Issue:3
| Computer-guided approach to access the anti-influenza activity of licorice constituents. |
| AID1073045 | Inhibition of Influenza A virus J/8178/09 neuraminidase by chemiluminescence based assay | 2014 | Journal of natural products, Mar-28, Volume: 77, Issue:3
| Computer-guided approach to access the anti-influenza activity of licorice constituents. |
| AID668116 | Hypnotic activity in fasted C57BL/6N mouse assessed as increase in pentobarbital-induced sleep duration at 50 mg/kg, po administered 45 mins prior to pentobarbital-induction coadministered with flumazenil by polysomnographic analysis | 2012 | Bioorganic & medicinal chemistry, Jun-01, Volume: 20, Issue:11
| Hypnotic effects and GABAergic mechanism of licorice (Glycyrrhiza glabra) ethanol extract and its major flavonoid constituent glabrol. |
| AID398785 | Antibacterial activity against Klebsiella pneumoniae ATCC 10031 at 100 mcg/ml by agar-dilution streak method | | | |
| AID1453610 | Growth inhibition of human LO2 cells at 10 uM after 24 hrs by MTS assay relative to control | 2017 | Bioorganic & medicinal chemistry, 07-15, Volume: 25, Issue:14
| Screening for bioactive natural products from a 67-compound library of Glycyrrhiza inflata. |
| AID668113 | Hypnotic activity in po dosed fasted C57BL/6N mouse assessed as increase in pentobarbital-induced sleep duration administered 45 mins prior to pentobarbital-induction by polysomnographic analysis | 2012 | Bioorganic & medicinal chemistry, Jun-01, Volume: 20, Issue:11
| Hypnotic effects and GABAergic mechanism of licorice (Glycyrrhiza glabra) ethanol extract and its major flavonoid constituent glabrol. |
| AID668110 | Displacement of [3H]flumazenil from GABA(A)-BZD receptor in Sprague-Dawley rat cerebral cortex membranes after 40 mins by liquid scintillation counting | 2012 | Bioorganic & medicinal chemistry, Jun-01, Volume: 20, Issue:11
| Hypnotic effects and GABAergic mechanism of licorice (Glycyrrhiza glabra) ethanol extract and its major flavonoid constituent glabrol. |
| AID398789 | Antifungal activity against Candida albicans ATCC 10231 at 100 mcg/ml by agar-dilution streak method | | | |
| AID1073033 | Inhibition of Clostridium perfringens neuraminidase by chemiluminescence based assay | 2014 | Journal of natural products, Mar-28, Volume: 77, Issue:3
| Computer-guided approach to access the anti-influenza activity of licorice constituents. |
| AID1453625 | Inhibition of mushroom tyrosinase at 10 uM using L-tyrosine as substrate incubated for 15 mins followed by substrate addition relative to control | 2017 | Bioorganic & medicinal chemistry, 07-15, Volume: 25, Issue:14
| Screening for bioactive natural products from a 67-compound library of Glycyrrhiza inflata. |
| AID1484045 | Antiproliferative activity against human HepG2 cells at 10 uM after 24 hrs by MTS assay relative to control | 2017 | Journal of natural products, 02-24, Volume: 80, Issue:2
| Glycybridins A-K, Bioactive Phenolic Compounds from Glycyrrhiza glabra. |
| AID1453623 | Inhibition of recombinant human PTP1B using p-nitrophenyl phosphate as substrate at 10 uM after 30 mins relative to control | 2017 | Bioorganic & medicinal chemistry, 07-15, Volume: 25, Issue:14
| Screening for bioactive natural products from a 67-compound library of Glycyrrhiza inflata. |
| AID398779 | Antibacterial activity against Staphylococcus aureus ATCC 13709 by agar-dilution streak method | | | |
| AID1175338 | Cytotoxicity against human HMC1 cells assessed as cell viability | 2014 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 24, Issue:24
| Flavonoids and arylbenzofurans from the rhizomes and roots of Sophora tonkinensis with IL-6 production inhibitory activity. |
| AID1073042 | Inhibition of Influenza A virus (A/Hong Kong/1/1968(H3N2)) neuraminidase by chemiluminescence based assay | 2014 | Journal of natural products, Mar-28, Volume: 77, Issue:3
| Computer-guided approach to access the anti-influenza activity of licorice constituents. |
| AID1073038 | Antiviral activity against Influenza A virus (A/Hong Kong/1/1968(H3N2)) infected in MDCK cells assessed as inhibition of virus-induced cytopathic effect at 50 uM after 48 hrs | 2014 | Journal of natural products, Mar-28, Volume: 77, Issue:3
| Computer-guided approach to access the anti-influenza activity of licorice constituents. |
| AID1453609 | Growth inhibition of human HEK293T cells at 10 uM after 24 hrs by MTS assay relative to control | 2017 | Bioorganic & medicinal chemistry, 07-15, Volume: 25, Issue:14
| Screening for bioactive natural products from a 67-compound library of Glycyrrhiza inflata. |
| AID1484037 | Inhibition of recombinant human PTP1B using pNPP as substrate at 10 uM after 30 mins relative to control | 2017 | Journal of natural products, 02-24, Volume: 80, Issue:2
| Glycybridins A-K, Bioactive Phenolic Compounds from Glycyrrhiza glabra. |
| AID398784 | Antibacterial activity against Salmonella gallinarum ATCC 9184 at 100 mcg/ml by agar-dilution streak method | | | |
| AID1073039 | Antiviral activity against Influenza A virus J/8178/09 infected in MDCK cells assessed as inhibition of virus-induced cytopathic effect at 50 uM after 48 hrs | 2014 | Journal of natural products, Mar-28, Volume: 77, Issue:3
| Computer-guided approach to access the anti-influenza activity of licorice constituents. |
| AID1484040 | Antiinflammatory activity against mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production at 10 uM after 24 hrs by Griess assay relative to control | 2017 | Journal of natural products, 02-24, Volume: 80, Issue:2
| Glycybridins A-K, Bioactive Phenolic Compounds from Glycyrrhiza glabra. |
| AID457748 | Binding affinity to human recombinant PPAGgamma expressed in african green monkey CV1 cells coexpressing GAL4-luc reporter by microplate scintillation counter | 2010 | Bioorganic & medicinal chemistry, Jan-15, Volume: 18, Issue:2
| Phenolics from Glycyrrhiza glabra roots and their PPAR-gamma ligand-binding activity. |
| AID1073037 | Cytotoxicity against MDCK cells after 72 hrs | 2014 | Journal of natural products, Mar-28, Volume: 77, Issue:3
| Computer-guided approach to access the anti-influenza activity of licorice constituents. |
| AID1453613 | Cytotoxicity against human HepG2 cells assessed as reduction in cell viability after 24 hrs by MTS assay | 2017 | Bioorganic & medicinal chemistry, 07-15, Volume: 25, Issue:14
| Screening for bioactive natural products from a 67-compound library of Glycyrrhiza inflata. |
| AID1453611 | Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 24 hrs by MTS assay | 2017 | Bioorganic & medicinal chemistry, 07-15, Volume: 25, Issue:14
| Screening for bioactive natural products from a 67-compound library of Glycyrrhiza inflata. |
| AID668115 | Hypnotic activity in fasted C57BL/6N mouse assessed as increase in pentobarbital-induced sleep duration at 50 mg/kg, po administered 45 mins prior to pentobarbital-induction by polysomnographic analysis | 2012 | Bioorganic & medicinal chemistry, Jun-01, Volume: 20, Issue:11
| Hypnotic effects and GABAergic mechanism of licorice (Glycyrrhiza glabra) ethanol extract and its major flavonoid constituent glabrol. |
| AID1484048 | Antiproliferative activity against human SW480 cells at 10 uM after 24 hrs by MTS assay relative to control | 2017 | Journal of natural products, 02-24, Volume: 80, Issue:2
| Glycybridins A-K, Bioactive Phenolic Compounds from Glycyrrhiza glabra. |
| AID1073035 | Induction of fluorescence quenching at 100 uM relative to 4-methylumbelliferone | 2014 | Journal of natural products, Mar-28, Volume: 77, Issue:3
| Computer-guided approach to access the anti-influenza activity of licorice constituents. |
| AID1073032 | Selectivity ratio of IC50 for Clostridium perfringens neuraminidase to IC50 for Influenza A virus neuraminidase | 2014 | Journal of natural products, Mar-28, Volume: 77, Issue:3
| Computer-guided approach to access the anti-influenza activity of licorice constituents. |
| AID1484046 | Antiproliferative activity against human A549 cells at 10 uM after 24 hrs by MTS assay relative to control | 2017 | Journal of natural products, 02-24, Volume: 80, Issue:2
| Glycybridins A-K, Bioactive Phenolic Compounds from Glycyrrhiza glabra. |
| AID1484042 | Inhibition of LPS-induced NF-kappaB (unknown origin) transactivation expressed in human SW480 cells at 10 uM administered 1 hr after LPS stimulation measured after 6 hrs by luciferase reporter gene assay relative to control | 2017 | Journal of natural products, 02-24, Volume: 80, Issue:2
| Glycybridins A-K, Bioactive Phenolic Compounds from Glycyrrhiza glabra. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |