| Assay ID | Title | Year | Journal | Article |
|---|
| AID1347159 | Primary screen GU Rhodamine qHTS for Zika virus inhibitors: Unlinked NS2B-NS3 protease assay | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1347160 | Primary screen NINDS Rhodamine qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1296008 | Cytotoxic Profiling of Annotated Libraries Using Quantitative High-Throughput Screening | 2020 | SLAS discovery : advancing life sciences R & D, 01, Volume: 25, Issue:1
| Cytotoxic Profiling of Annotated and Diverse Chemical Libraries Using Quantitative High-Throughput Screening. |
| AID1346986 | P-glycoprotein substrates identified in KB-3-1 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5
| A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
| AID1346987 | P-glycoprotein substrates identified in KB-8-5-11 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5
| A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
| AID1684858 | Antiproliferative activity against human HT-29 cells cultured as 3D-spheroids assessed as reduction in cell viability by Celltiter-Glo assay | 2021 | ACS medicinal chemistry letters, Jan-14, Volume: 12, Issue:1
| Discovery of a Pyrimidothiazolodiazepinone as a Potent and Selective Focal Adhesion Kinase (FAK) Inhibitor. |
| AID1675123 | Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability | 2020 | Bioorganic & medicinal chemistry letters, 11-01, Volume: 30, Issue:21
| Design, synthesis and biological evaluation of ring-fused pyrazoloamino pyridine/pyrimidine derivatives as potential FAK inhibitors. |
| AID1675126 | Inhibition of FAK (unknown origin) | 2020 | Bioorganic & medicinal chemistry letters, 11-01, Volume: 30, Issue:21
| Design, synthesis and biological evaluation of ring-fused pyrazoloamino pyridine/pyrimidine derivatives as potential FAK inhibitors. |
| AID1675120 | Antiproliferative activity against human DU-145 cells assessed as reduction in cell viability | 2020 | Bioorganic & medicinal chemistry letters, 11-01, Volume: 30, Issue:21
| Design, synthesis and biological evaluation of ring-fused pyrazoloamino pyridine/pyrimidine derivatives as potential FAK inhibitors. |
| AID1755627 | Inhibition of GST-fused FAK (411 to 686 residues) (unknown origin) expressed in sf9 cells using poly(Glu:Tyr) (4:1) copolymer as substrate by spectrophotometric method | 2020 | Journal of medicinal chemistry, 12-10, Volume: 63, Issue:23
| Progress in the Development of Small Molecular Inhibitors of Focal Adhesion Kinase (FAK). |
| AID1675122 | Antiproliferative activity against human BXPC-3 cells assessed as reduction in cell viability | 2020 | Bioorganic & medicinal chemistry letters, 11-01, Volume: 30, Issue:21
| Design, synthesis and biological evaluation of ring-fused pyrazoloamino pyridine/pyrimidine derivatives as potential FAK inhibitors. |
| AID1675119 | Antiproliferative activity against human 786-O cells assessed as reduction in cell viability | 2020 | Bioorganic & medicinal chemistry letters, 11-01, Volume: 30, Issue:21
| Design, synthesis and biological evaluation of ring-fused pyrazoloamino pyridine/pyrimidine derivatives as potential FAK inhibitors. |
| AID1675121 | Antiproliferative activity against human NCI-H1975 cells assessed as reduction in cell viability | 2020 | Bioorganic & medicinal chemistry letters, 11-01, Volume: 30, Issue:21
| Design, synthesis and biological evaluation of ring-fused pyrazoloamino pyridine/pyrimidine derivatives as potential FAK inhibitors. |
| AID1755628 | Cytotoxicity against human RD cells incubated for 96 hrs by DIMSCAN method | 2020 | Journal of medicinal chemistry, 12-10, Volume: 63, Issue:23
| Progress in the Development of Small Molecular Inhibitors of Focal Adhesion Kinase (FAK). |
| AID1675124 | Inhibition of tracer 236 binding to recombinant human GST-tagged full length FAK expressed in baculovirus expression system incubated for 1 hr by Lanthascreen TR-FRET assay | 2020 | Bioorganic & medicinal chemistry letters, 11-01, Volume: 30, Issue:21
| Design, synthesis and biological evaluation of ring-fused pyrazoloamino pyridine/pyrimidine derivatives as potential FAK inhibitors. |
| AID1684841 | Inhibition of GST-FAK catalytic domain region (411-686) (unknown origin) expressed in baculovirus infected Sf9 cells by spectrophotometry | 2021 | ACS medicinal chemistry letters, Jan-14, Volume: 12, Issue:1
| Discovery of a Pyrimidothiazolodiazepinone as a Potent and Selective Focal Adhesion Kinase (FAK) Inhibitor. |
| AID1684860 | Antiproliferative activity against human HT-29 cells cultured as 2D-adherent monolayer assessed as reduction in cell viability by Celltiter-Glo assay | 2021 | ACS medicinal chemistry letters, Jan-14, Volume: 12, Issue:1
| Discovery of a Pyrimidothiazolodiazepinone as a Potent and Selective Focal Adhesion Kinase (FAK) Inhibitor. |
| AID1345884 | Human protein tyrosine kinase 2 (Fak family) | 2010 | Cancer biology & therapy, May-15, Volume: 9, Issue:10
| PND-1186 FAK inhibitor selectively promotes tumor cell apoptosis in three-dimensional environments. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |