| Assay ID | Title | Year | Journal | Article |
|---|
| AID186553 | Base line of mean aortic blood pressure in the conscious Renal hypertensive rat was determined after oral administration of 30 mg/kg | 1982 | Journal of medicinal chemistry, Nov, Volume: 25, Issue:11
| Derivatives of the potent angiotensin converting enzyme inhibitor 5(S)-benzamido-4-oxo-6-phenylhexanoyl-L-proline: effect of changes at positions 2 and 5 of the hexanoic acid portion. |
| AID271474 | Inhibition of rabbit testis recombinant ACE C domain | 2006 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 16, Issue:17
| Synthesis of novel keto-ACE analogues as domain-selective angiotensin I-converting enzyme inhibitors. |
| AID193332 | Change in mean aortic blood pressure in the conscious renal hypertensive rat after oral administration of 30 mg/kg | 1981 | Journal of medicinal chemistry, Aug, Volume: 24, Issue:8
| Novel synthesis of (S)-1-[5-(benzoylamino)-1,4-dioxo-6-phenylhexyl]-L-proline and analogues: potent angiotensin converting enzyme inhibitors. |
| AID169780 | Inhibition of blood pressure increase produced by iv injection of angiotensin I in conscious normotensive rats at a dose of 3 mg/kg | 1982 | Journal of medicinal chemistry, Nov, Volume: 25, Issue:11
| Derivatives of the potent angiotensin converting enzyme inhibitor 5(S)-benzamido-4-oxo-6-phenylhexanoyl-L-proline: effect of changes at positions 2 and 5 of the hexanoic acid portion. |
| AID183224 | Inhibition of blood pressure increase produced by iv injection of angiotensin I in conscious normotensive rats at a dose of 3 mg/kg | 1982 | Journal of medicinal chemistry, Nov, Volume: 25, Issue:11
| Derivatives of the potent angiotensin converting enzyme inhibitor 5(S)-benzamido-4-oxo-6-phenylhexanoyl-L-proline: effect of changes at positions 2 and 5 of the hexanoic acid portion. |
| AID38852 | In vitro inhibitory activity against Angiotensin I converting enzyme | 1985 | Journal of medicinal chemistry, Apr, Volume: 28, Issue:4
| Angiotensin-converting enzyme inhibitors: synthesis and biological activity of acyl tripeptide analogues of enalapril. |
| AID194499 | Maximum effect of 30 mg/kg administered orally on mean aortic blood pressure in the conscious renal hypertensive rat | 1981 | Journal of medicinal chemistry, Aug, Volume: 24, Issue:8
| Novel synthesis of (S)-1-[5-(benzoylamino)-1,4-dioxo-6-phenylhexyl]-L-proline and analogues: potent angiotensin converting enzyme inhibitors. |
| AID186563 | Compound was evaluated for itschange in blood pressure value on hypertensive rats by peroral administration at a dose of 30 mg/kg at 8 hr | 1985 | Journal of medicinal chemistry, Aug, Volume: 28, Issue:8
| Synthesis and biological activity of pentapeptide analogues of the potent angiotensin converting enzyme inhibitor 5(S)-benzamido-4-oxo-6-phenylhexanoyl-L-proline. |
| AID37635 | Compound is evaluated for the inhibition of porcine plasma Angiotensin I converting enzyme | 1980 | Journal of medicinal chemistry, Dec, Volume: 23, Issue:12
| Synthesis and biological activity of a ketomethylene analogue of a tripeptide inhibitor of angiotensin converting enzyme. |
| AID271475 | Inhibition of recombinant ACE N domain | 2006 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 16, Issue:17
| Synthesis of novel keto-ACE analogues as domain-selective angiotensin I-converting enzyme inhibitors. |
| AID228126 | Enzyme kinetic inhibition constant against tripeptide, Hip-His-Leu as substrate | 1980 | Journal of medicinal chemistry, Dec, Volume: 23, Issue:12
| Synthesis and biological activity of a ketomethylene analogue of a tripeptide inhibitor of angiotensin converting enzyme. |
| AID228125 | Enzyme kinetic inhibition constant against tripeptide, Angiotensin I as substrate in a competition inhibition assay | 1980 | Journal of medicinal chemistry, Dec, Volume: 23, Issue:12
| Synthesis and biological activity of a ketomethylene analogue of a tripeptide inhibitor of angiotensin converting enzyme. |
| AID37964 | Inhibition of Angiotensin I converting enzyme in normotensive rat | 1988 | Journal of medicinal chemistry, Mar, Volume: 31, Issue:3
| Synthesis and biological activity of ketomethylene-containing nonapeptide analogues of snake venom angiotensin converting enzyme inhibitors. |
| AID39752 | Inhibition of guinea pig serum Angiotensin I converting enzyme | 1982 | Journal of medicinal chemistry, Nov, Volume: 25, Issue:11
| Derivatives of the potent angiotensin converting enzyme inhibitor 5(S)-benzamido-4-oxo-6-phenylhexanoyl-L-proline: effect of changes at positions 2 and 5 of the hexanoic acid portion. |
| AID78673 | Compound is evaluated for the inhibition of guinea pig ileum contraction caused by 25 ng/mL angiotensin I | 1980 | Journal of medicinal chemistry, Dec, Volume: 23, Issue:12
| Synthesis and biological activity of a ketomethylene analogue of a tripeptide inhibitor of angiotensin converting enzyme. |
| AID169775 | Angiotensin I(AI) response to return to 70% of the pretreatment control response was determined at a dose of 30 mg/kg | 1982 | Journal of medicinal chemistry, Nov, Volume: 25, Issue:11
| Derivatives of the potent angiotensin converting enzyme inhibitor 5(S)-benzamido-4-oxo-6-phenylhexanoyl-L-proline: effect of changes at positions 2 and 5 of the hexanoic acid portion. |
| AID183223 | Inhibition of blood pressure increase produced by iv injection of angiotensin I in conscious normotensive rats at a dose of 30 mg/kg | 1982 | Journal of medicinal chemistry, Nov, Volume: 25, Issue:11
| Derivatives of the potent angiotensin converting enzyme inhibitor 5(S)-benzamido-4-oxo-6-phenylhexanoyl-L-proline: effect of changes at positions 2 and 5 of the hexanoic acid portion. |
| AID169783 | Time required after administration of 3 mg/kg of compound iv, for the AI response to return to 70% of the pretreatment control response | 1981 | Journal of medicinal chemistry, Aug, Volume: 24, Issue:8
| Novel synthesis of (S)-1-[5-(benzoylamino)-1,4-dioxo-6-phenylhexyl]-L-proline and analogues: potent angiotensin converting enzyme inhibitors. |
| AID169785 | Time required after administration of 30 mg/kg of compound po, for the AI response to return to 70% of the pretreatment control response | 1981 | Journal of medicinal chemistry, Aug, Volume: 24, Issue:8
| Novel synthesis of (S)-1-[5-(benzoylamino)-1,4-dioxo-6-phenylhexyl]-L-proline and analogues: potent angiotensin converting enzyme inhibitors. |
| AID186260 | Maximum inhibition of the angiotensin I challenge at 3 mg/kg, iv, in conscious, normotensive rats | 1981 | Journal of medicinal chemistry, Aug, Volume: 24, Issue:8
| Novel synthesis of (S)-1-[5-(benzoylamino)-1,4-dioxo-6-phenylhexyl]-L-proline and analogues: potent angiotensin converting enzyme inhibitors. |
| AID171886 | Change in mean aortic blood pressure expressed in hours after an oral administration of 3 mg/kg in conscious normotensive rats | 1982 | Journal of medicinal chemistry, Nov, Volume: 25, Issue:11
| Derivatives of the potent angiotensin converting enzyme inhibitor 5(S)-benzamido-4-oxo-6-phenylhexanoyl-L-proline: effect of changes at positions 2 and 5 of the hexanoic acid portion. |
| AID39018 | Inhibitory activity against angiotensin converting enzyme (ACE) | 1993 | Journal of medicinal chemistry, Aug-06, Volume: 36, Issue:16
| Three-dimensional quantitative structure-activity relationship of angiotesin-converting enzyme and thermolysin inhibitors. II. A comparison of CoMFA models incorporating molecular orbital fields and desolvation free energies based on active-analog and com |
| AID186259 | Maximum inhibition of the angiotensin I challenge at 30mg/kg, po in conscious, normotensive rats | 1981 | Journal of medicinal chemistry, Aug, Volume: 24, Issue:8
| Novel synthesis of (S)-1-[5-(benzoylamino)-1,4-dioxo-6-phenylhexyl]-L-proline and analogues: potent angiotensin converting enzyme inhibitors. |
| AID39756 | Concentration required for 50% inhibition of Angiotensin I converting enzyme | 1982 | Journal of medicinal chemistry, Aug, Volume: 25, Issue:8
| Angiotensin converting enzyme inhibitors: modifications of a tripeptide analogue. |
| AID39754 | Concentration required to inhibit the activity of Angiotensin I converting enzyme by 50% | 1981 | Journal of medicinal chemistry, Aug, Volume: 24, Issue:8
| Novel synthesis of (S)-1-[5-(benzoylamino)-1,4-dioxo-6-phenylhexyl]-L-proline and analogues: potent angiotensin converting enzyme inhibitors. |
| AID186566 | Maximum effect on blood pressure in the conscious Renal hypertensive rat after oral administration of 30 mg/kg | 1982 | Journal of medicinal chemistry, Nov, Volume: 25, Issue:11
| Derivatives of the potent angiotensin converting enzyme inhibitor 5(S)-benzamido-4-oxo-6-phenylhexanoyl-L-proline: effect of changes at positions 2 and 5 of the hexanoic acid portion. |
| AID271476 | Selectivity for rabbit testis ACE C domain over human ACE N domain | 2006 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 16, Issue:17
| Synthesis of novel keto-ACE analogues as domain-selective angiotensin I-converting enzyme inhibitors. |
| AID186559 | Compound was evaluated for its base line value on hypertensive rats by peroral administration at a dose of 30 mg/kg | 1985 | Journal of medicinal chemistry, Aug, Volume: 28, Issue:8
| Synthesis and biological activity of pentapeptide analogues of the potent angiotensin converting enzyme inhibitor 5(S)-benzamido-4-oxo-6-phenylhexanoyl-L-proline. |
| AID186561 | Compound was evaluated for its maximum effect value on hypertensive rats by peroral administration at a dose of 30 mg/kg | 1985 | Journal of medicinal chemistry, Aug, Volume: 28, Issue:8
| Synthesis and biological activity of pentapeptide analogues of the potent angiotensin converting enzyme inhibitor 5(S)-benzamido-4-oxo-6-phenylhexanoyl-L-proline. |
| AID37636 | Compound was evaluated for inhibition of porcine plasma Angiotensin I converting enzyme by using fluorometric assay | 1985 | Journal of medicinal chemistry, Aug, Volume: 28, Issue:8
| Synthesis and biological activity of pentapeptide analogues of the potent angiotensin converting enzyme inhibitor 5(S)-benzamido-4-oxo-6-phenylhexanoyl-L-proline. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |