| Assay ID | Title | Year | Journal | Article |
|---|
| AID1578702 | Inhibition of human TRPC1/mouse TRPC4 beta expressed in HEK293 cells co-expressing M2 receptor assessed as reduction in catechol-evoked membrane potential by FMP-2 dye based assay | 2019 | Journal of medicinal chemistry, 09-12, Volume: 62, Issue:17
| Review of Transient Receptor Potential Canonical (TRPC5) Channel Modulators and Diseases. |
| AID1578703 | Drug concentration in C57BL/6 mouse serum at 10 mg/kg, ip after 2 hrs by UPLC method | 2019 | Journal of medicinal chemistry, 09-12, Volume: 62, Issue:17
| Review of Transient Receptor Potential Canonical (TRPC5) Channel Modulators and Diseases. |
| AID1578693 | Inhibition of mouse TRPC4 beta expressed in HEK293 cells co-expressing mu-opioid receptor assessed as reduction in DAMGO-induced intracellular calcium level in presence of mu-opioid receptor agonist DAMGO by Fluo-4AM dye based fluorescence assay | 2019 | Journal of medicinal chemistry, 09-12, Volume: 62, Issue:17
| Review of Transient Receptor Potential Canonical (TRPC5) Channel Modulators and Diseases. |
| AID1578699 | Inhibition of mouse TRPC5 expressed in HEK293 cells co-expressing mu-opioid receptor assessed as reduction in DAMGO-induced membrane potential by FMP-2 dye based assay | 2019 | Journal of medicinal chemistry, 09-12, Volume: 62, Issue:17
| Review of Transient Receptor Potential Canonical (TRPC5) Channel Modulators and Diseases. |
| AID756028 | Inhibition of human AchE using acetylthiocholine iodide as substrate incubated for 20 mins prior to substrate addition measured for 1 hr by Ellman's method | 2013 | Bioorganic & medicinal chemistry, Jul-15, Volume: 21, Issue:14
| Synthesis, biological evaluation and molecular modeling of substituted 2-aminobenzimidazoles as novel inhibitors of acetylcholinesterase and butyrylcholinesterase. |
| AID1578705 | Drug concentration in C57BL/6 mouse cerebrospinal fluid at 10 mg/kg, ip after 2 hrs by UPLC method | 2019 | Journal of medicinal chemistry, 09-12, Volume: 62, Issue:17
| Review of Transient Receptor Potential Canonical (TRPC5) Channel Modulators and Diseases. |
| AID756027 | Inhibition of human BuChE using butyrylthiocholine iodide as substrate incubated for 20 mins prior to substrate addition measured for 1 hr by Ellman's method | 2013 | Bioorganic & medicinal chemistry, Jul-15, Volume: 21, Issue:14
| Synthesis, biological evaluation and molecular modeling of substituted 2-aminobenzimidazoles as novel inhibitors of acetylcholinesterase and butyrylcholinesterase. |
| AID1578701 | Inhibition of human TRPC3 expressed in HEK293 cells assessed as reduction in carbachol-induced membrane potential by FMP-2 dye based assay | 2019 | Journal of medicinal chemistry, 09-12, Volume: 62, Issue:17
| Review of Transient Receptor Potential Canonical (TRPC5) Channel Modulators and Diseases. |
| AID1578704 | Drug concentration in C57BL/6 mouse brain at 10 mg/kg, ip after 2 hrs by UPLC method | 2019 | Journal of medicinal chemistry, 09-12, Volume: 62, Issue:17
| Review of Transient Receptor Potential Canonical (TRPC5) Channel Modulators and Diseases. |
| AID1578700 | Inhibition of mouse TRPC6 expressed in HEK293 cells co-expressing M5 receptor assessed as reduction in carbachol-induced membrane potential by FMP-2 dye based assay | 2019 | Journal of medicinal chemistry, 09-12, Volume: 62, Issue:17
| Review of Transient Receptor Potential Canonical (TRPC5) Channel Modulators and Diseases. |
| AID756024 | Cytotoxicity against human HepG2 cells assessed as cell viability at 100 uM after 48 hrs by MTT assay | 2013 | Bioorganic & medicinal chemistry, Jul-15, Volume: 21, Issue:14
| Synthesis, biological evaluation and molecular modeling of substituted 2-aminobenzimidazoles as novel inhibitors of acetylcholinesterase and butyrylcholinesterase. |
| AID1578698 | Inhibition of mouse TRPC4 beta expressed in HEK293 cells co-expressing mu-opioid receptor assessed as reduction in DAMGO-induced membrane potential by FMP-2 dye based assay | 2019 | Journal of medicinal chemistry, 09-12, Volume: 62, Issue:17
| Review of Transient Receptor Potential Canonical (TRPC5) Channel Modulators and Diseases. |
| AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1
| High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1
| High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID504812 | Inverse Agonists of the Thyroid Stimulating Hormone Receptor: HTS campaign | 2010 | Endocrinology, Jul, Volume: 151, Issue:7
| A small molecule inverse agonist for the human thyroid-stimulating hormone receptor. |
| AID1745845 | Primary qHTS for Inhibitors of ATXN expression | | | |
| AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1
| High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID504810 | Antagonists of the Thyroid Stimulating Hormone Receptor: HTS campaign | 2010 | Endocrinology, Jul, Volume: 151, Issue:7
| A small molecule inverse agonist for the human thyroid-stimulating hormone receptor. |
| AID651635 | Viability Counterscreen for Primary qHTS for Inhibitors of ATXN expression | | | |
| AID540299 | A screen for compounds that inhibit the MenB enzyme of Mycobacterium tuberculosis | 2010 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 20, Issue:21
| Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. |
| AID588519 | A screen for compounds that inhibit viral RNA polymerase binding and polymerization activities | 2011 | Antiviral research, Sep, Volume: 91, Issue:3
| High-throughput screening identification of poliovirus RNA-dependent RNA polymerase inhibitors. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |