| Assay ID | Title | Year | Journal | Article |
|---|
| AID211045 | In vitro inhibition of human thrombin(FIIa). | 1999 | Journal of medicinal chemistry, Dec-30, Volume: 42, Issue:26
| Synthesis, characterization, and structure-activity relationships of amidine-substituted (bis)benzylidene-cycloketone olefin isomers as potent and selective factor Xa inhibitors. |
| AID51652 | Compound (isomer) was tested in the absence of light for inhibitory activity against Human Coagulation factor X | 1998 | Journal of medicinal chemistry, Sep-10, Volume: 41, Issue:19
| (Z,Z)-2,7-Bis(4-amidinobenzylidene)cycloheptan-1-one: identification of a highly active inhibitor of blood coagulation factor Xa. |
| AID51676 | Inhibitory potency was measured against human coagulation factor X | 1998 | Journal of medicinal chemistry, Sep-10, Volume: 41, Issue:19
| Discovery of N-[2-[5-[Amino(imino)methyl]-2-hydroxyphenoxy]-3, 5-difluoro-6-[3-(4, 5-dihydro-1-methyl-1H-imidazol-2-yl)phenoxy]pyridin-4-yl]-N-methylgl y cine (ZK-807834): a potent, selective, and orally active inhibitor of the blood coagulation enzyme fa |
| AID215209 | Inhibitory potency was measured against bovine trypsin. | 1998 | Journal of medicinal chemistry, Sep-10, Volume: 41, Issue:19
| Discovery of N-[2-[5-[Amino(imino)methyl]-2-hydroxyphenoxy]-3, 5-difluoro-6-[3-(4, 5-dihydro-1-methyl-1H-imidazol-2-yl)phenoxy]pyridin-4-yl]-N-methylgl y cine (ZK-807834): a potent, selective, and orally active inhibitor of the blood coagulation enzyme fa |
| AID7226 | In vitro inhibition of bovine trypsin(Trp). | 1999 | Journal of medicinal chemistry, Dec-30, Volume: 42, Issue:26
| Synthesis, characterization, and structure-activity relationships of amidine-substituted (bis)benzylidene-cycloketone olefin isomers as potent and selective factor Xa inhibitors. |
| AID211218 | Inhibitory potency was measured against human thrombin | 1998 | Journal of medicinal chemistry, Sep-10, Volume: 41, Issue:19
| Discovery of N-[2-[5-[Amino(imino)methyl]-2-hydroxyphenoxy]-3, 5-difluoro-6-[3-(4, 5-dihydro-1-methyl-1H-imidazol-2-yl)phenoxy]pyridin-4-yl]-N-methylgl y cine (ZK-807834): a potent, selective, and orally active inhibitor of the blood coagulation enzyme fa |
| AID51657 | Compound was tested for inhibitory activity against human Coagulation factor X | 1998 | Bioorganic & medicinal chemistry letters, Aug-18, Volume: 8, Issue:16
| Design, synthesis, and biological activity of novel purine and bicyclic pyrimidine factor Xa inhibitors. |
| AID51847 | Binding affinity was evaluated against Coagulation factor X | 1998 | Bioorganic & medicinal chemistry letters, Jul-21, Volume: 8, Issue:14
| Solid-phase synthesis of N-substituted amidinophenoxy pyridines as factor XA inhibitors. |
| AID51669 | Inhibitory activity against human Coagulation factor X | 2000 | Bioorganic & medicinal chemistry letters, May-01, Volume: 10, Issue:9
| Design, synthesis, and in vitro biological activity of indole-based factor Xa inhibitors. |
| AID52158 | In vitro inhibition of human coagulation factor Xa (Xa) in a purified enzyme system. | 1999 | Journal of medicinal chemistry, Dec-30, Volume: 42, Issue:26
| Synthesis, characterization, and structure-activity relationships of amidine-substituted (bis)benzylidene-cycloketone olefin isomers as potent and selective factor Xa inhibitors. |
| AID215191 | Compound was tested for inhibitory activity against bovine trypsin | 1998 | Bioorganic & medicinal chemistry letters, Aug-18, Volume: 8, Issue:16
| Design, synthesis, and biological activity of novel purine and bicyclic pyrimidine factor Xa inhibitors. |
| AID211009 | Compound (isomer) was tested in the absence of light for inhibitory activity against thrombin. | 1998 | Journal of medicinal chemistry, Sep-10, Volume: 41, Issue:19
| (Z,Z)-2,7-Bis(4-amidinobenzylidene)cycloheptan-1-one: identification of a highly active inhibitor of blood coagulation factor Xa. |
| AID215060 | Compound (isomer) was tested in the absence of light for inhibitory activity against trypsin. | 1998 | Journal of medicinal chemistry, Sep-10, Volume: 41, Issue:19
| (Z,Z)-2,7-Bis(4-amidinobenzylidene)cycloheptan-1-one: identification of a highly active inhibitor of blood coagulation factor Xa. |
| AID211036 | Compound was tested for inhibitory activity against human thrombin | 1998 | Bioorganic & medicinal chemistry letters, Aug-18, Volume: 8, Issue:16
| Design, synthesis, and biological activity of novel purine and bicyclic pyrimidine factor Xa inhibitors. |
| AID1797608 | Enzyme Inhibition Assay from Article 10.1107/s0907444999007350: \\Crystallographic analysis of potent and selective factor Xa inhibitors complexed to bovine trypsin.\\ | 1999 | Acta crystallographica. Section D, Biological crystallography, Aug, Volume: 55, Issue:Pt 8
| Crystallographic analysis of potent and selective factor Xa inhibitors complexed to bovine trypsin. |
| AID977610 | Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB | 2004 | Journal of molecular biology, Jan-30, Volume: 335, Issue:5
| Understanding protein-ligand interactions: the price of protein flexibility. |
| AID1811 | Experimentally measured binding affinity data derived from PDB | 2004 | Journal of molecular biology, Jan-30, Volume: 335, Issue:5
| Understanding protein-ligand interactions: the price of protein flexibility. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |