Compounds > 3-isomangostin
Page last updated: 2024-11-12

3-isomangostin

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth

Description

3-isomangostin: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID13873655
CHEMBL ID464119
CHEBI ID175290
SCHEMBL ID15006537
MeSH IDM0295604

Synonyms (24)

Synonym
5,9-dihydroxy-8-methoxy-2,2-dimethyl-7-(3-methylbut-2-enyl)-3,4-dihydropyrano[3,2-b]xanthen-6-one
3-isomangostin
CHEBI:175290
CHEMBL464119 ,
FT-0686567
19275-46-8
SCHEMBL15006537
5,9-dihydroxy-8-methoxy-2,2-dimethyl-7-(3-methylbut-2-en-1-yl)-3,4-dihydro-2h,6h-pyrano[3,2-b]xanthen-6-one
Q-100233
5,9-dihydroxy-8-methoxy-2,2-dimethyl-7-(3-methylbut-2-en-1-yl)-2,3,4,6-tetrahydro-1,11-dioxatetracen-6-one
3,4-dihydro-5,9-dihydroxy-8-methoxy-2,2-dimethyl-7-(3-methyl-2-butenyl)-2h,6h-pyrano[3,2-b]xanthen-6-one
AKOS030573566
Q27463227
mfcd10566618
CS-0027793
HY-N6845
MS-27078
2h,6h-pyrano[3,2-b]xanthen-6-one, 3,4-dihydro-5,9-dihydroxy-8-methoxy-2,2-dimethyl-7-(3-methyl-2-butenyl)-
bdbm50509698
DTXSID701317245
PD125098
8-methoxy-2,2-dimethyl-7-(3-methylbut-2-enyl)-5,9-bis(oxidanyl)-3,4-dihydropyrano(3,2-b)xanthen-6-one
5,9-dihydroxy-8-methoxy-2,2-dimethyl-7-(3-methyl-2-butenyl)-3,4-dihydro-2h,6h-pyrano[3,2-b]xanthen-6-one
2RCN2CT95D
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

ClassDescription
xanthonesAny member of the class of xanthenes based on a xanthone skeleton.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Protein Targets (1)

Inhibition Measurements

ProteinTaxonomyMeasurementAverageMin (ref.)Avg (ref.)Max (ref.)Bioassay(s)
7,8-dihydro-8-oxoguanine triphosphataseHomo sapiens (human)IC50 (µMol)0.05200.05201.20935.6000AID1542231
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Biological Processes (6)

Processvia Protein(s)Taxonomy
purine nucleoside catabolic process7,8-dihydro-8-oxoguanine triphosphataseHomo sapiens (human)
DNA repair7,8-dihydro-8-oxoguanine triphosphataseHomo sapiens (human)
response to oxidative stress7,8-dihydro-8-oxoguanine triphosphataseHomo sapiens (human)
male gonad development7,8-dihydro-8-oxoguanine triphosphataseHomo sapiens (human)
DNA protection7,8-dihydro-8-oxoguanine triphosphataseHomo sapiens (human)
response to cadmium ion7,8-dihydro-8-oxoguanine triphosphataseHomo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Molecular Functions (13)

Processvia Protein(s)Taxonomy
5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase activity7,8-dihydro-8-oxoguanine triphosphataseHomo sapiens (human)
protein binding7,8-dihydro-8-oxoguanine triphosphataseHomo sapiens (human)
8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity7,8-dihydro-8-oxoguanine triphosphataseHomo sapiens (human)
dATP diphosphatase activity7,8-dihydro-8-oxoguanine triphosphataseHomo sapiens (human)
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides7,8-dihydro-8-oxoguanine triphosphataseHomo sapiens (human)
snoRNA binding7,8-dihydro-8-oxoguanine triphosphataseHomo sapiens (human)
8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity7,8-dihydro-8-oxoguanine triphosphataseHomo sapiens (human)
metal ion binding7,8-dihydro-8-oxoguanine triphosphataseHomo sapiens (human)
ATP diphosphatase activity7,8-dihydro-8-oxoguanine triphosphataseHomo sapiens (human)
2-hydroxy-ATP hydrolase activity7,8-dihydro-8-oxoguanine triphosphataseHomo sapiens (human)
2-hydroxy-dATP hydrolase activity7,8-dihydro-8-oxoguanine triphosphataseHomo sapiens (human)
N6-methyl-(d)ATP hydrolase activity7,8-dihydro-8-oxoguanine triphosphataseHomo sapiens (human)
O6-methyl-dGTP hydrolase activity7,8-dihydro-8-oxoguanine triphosphataseHomo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Ceullar Components (8)

Processvia Protein(s)Taxonomy
acrosomal vesicle7,8-dihydro-8-oxoguanine triphosphataseHomo sapiens (human)
extracellular space7,8-dihydro-8-oxoguanine triphosphataseHomo sapiens (human)
nucleus7,8-dihydro-8-oxoguanine triphosphataseHomo sapiens (human)
cytoplasm7,8-dihydro-8-oxoguanine triphosphataseHomo sapiens (human)
mitochondrion7,8-dihydro-8-oxoguanine triphosphataseHomo sapiens (human)
mitochondrial matrix7,8-dihydro-8-oxoguanine triphosphataseHomo sapiens (human)
cytosol7,8-dihydro-8-oxoguanine triphosphataseHomo sapiens (human)
nuclear membrane7,8-dihydro-8-oxoguanine triphosphataseHomo sapiens (human)
cytoplasm7,8-dihydro-8-oxoguanine triphosphataseHomo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Bioassays (41)

Assay IDTitleYearJournalArticle
AID398909Antifungal activity against Alternaria tenuis at 1000 ppm after 168 hrs at 24 hrs intervals1997Journal of natural products, May, Volume: 60, Issue:5
Evaluation of the antifungal activity of natural xanthones from Garcinia mangostana and their synthetic derivatives.
AID1723631Antibacterial activity against Enterococcus faecalis TISTR 4592020Bioorganic & medicinal chemistry letters, 10-15, Volume: 30, Issue:20
Modified tetra-oxygenated xanthones analogues as anti-MRSA and P. aeruginosa agent and their synergism with vancomycin.
AID399166Antifungal activity against Fusarium oxysporum vasinfectum at 100 ppm after 144 hrs at 24 hrs intervals1997Journal of natural products, May, Volume: 60, Issue:5
Evaluation of the antifungal activity of natural xanthones from Garcinia mangostana and their synthetic derivatives.
AID1140149Cytotoxicity against human AsPC1 cells assessed as inhibition of cell proliferation after 48 hrs by XTT assay2014Bioorganic & medicinal chemistry letters, May-01, Volume: 24, Issue:9
Synthesis of xanthone derivatives based on α-mangostin and their biological evaluation for anti-cancer agents.
AID1723636Induction of morphological changes in methicillin-resistant Staphylococcus aureus ATCC 43300 assessed as cell deformation incubated for 24 hrs by scanning electron microscopic method2020Bioorganic & medicinal chemistry letters, 10-15, Volume: 30, Issue:20
Modified tetra-oxygenated xanthones analogues as anti-MRSA and P. aeruginosa agent and their synergism with vancomycin.
AID1723639Synergistic antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC 43300 assessed as fractional inhibitory concentration index in presence of vancomycin2020Bioorganic & medicinal chemistry letters, 10-15, Volume: 30, Issue:20
Modified tetra-oxygenated xanthones analogues as anti-MRSA and P. aeruginosa agent and their synergism with vancomycin.
AID399162Antifungal activity against Drechslera oryzae at 100 ppm after 168 hrs at 24 hrs intervals1997Journal of natural products, May, Volume: 60, Issue:5
Evaluation of the antifungal activity of natural xanthones from Garcinia mangostana and their synthetic derivatives.
AID1723629Antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC 433002020Bioorganic & medicinal chemistry letters, 10-15, Volume: 30, Issue:20
Modified tetra-oxygenated xanthones analogues as anti-MRSA and P. aeruginosa agent and their synergism with vancomycin.
AID1525035Cytotoxicity in human HepG2 cells incubated for 72 hrs by MTT assay2019Journal of natural products, 05-24, Volume: 82, Issue:5
Tetrandraxanthones A-I, Prenylated and Geranylated Xanthones from the Stem Bark of Garcinia tetrandra.
AID1525034Cytotoxicity in human MCF7 cells incubated for 72 hrs by MTT assay2019Journal of natural products, 05-24, Volume: 82, Issue:5
Tetrandraxanthones A-I, Prenylated and Geranylated Xanthones from the Stem Bark of Garcinia tetrandra.
AID1723630Antibacterial activity against Bacillus subtilis2020Bioorganic & medicinal chemistry letters, 10-15, Volume: 30, Issue:20
Modified tetra-oxygenated xanthones analogues as anti-MRSA and P. aeruginosa agent and their synergism with vancomycin.
AID1525032Cytotoxicity in human KB cells incubated for 72 hrs by MTT assay2019Journal of natural products, 05-24, Volume: 82, Issue:5
Tetrandraxanthones A-I, Prenylated and Geranylated Xanthones from the Stem Bark of Garcinia tetrandra.
AID399161Antifungal activity against Drechslera oryzae at 10 ppm after 168 hrs at 24 hrs intervals1997Journal of natural products, May, Volume: 60, Issue:5
Evaluation of the antifungal activity of natural xanthones from Garcinia mangostana and their synthetic derivatives.
AID468110Inhibition of nuclear factor NF-kappa-B p65 subunit after 1 hr by ELISA2009Journal of natural products, Nov, Volume: 72, Issue:11
Cytotoxic xanthone constituents of the stem bark of Garcinia mangostana (mangosteen).
AID398907Antifungal activity against Alternaria tenuis at 10 ppm after 168 hrs at 24 hrs intervals1997Journal of natural products, May, Volume: 60, Issue:5
Evaluation of the antifungal activity of natural xanthones from Garcinia mangostana and their synthetic derivatives.
AID398910Antifungal activity against Drechslera oryzae at 1 ppm after 168 hrs at 24 hrs intervals1997Journal of natural products, May, Volume: 60, Issue:5
Evaluation of the antifungal activity of natural xanthones from Garcinia mangostana and their synthetic derivatives.
AID1140147Cytotoxicity against human NCI-H460 cells assessed as inhibition of cell proliferation after 48 hrs by XTT assay2014Bioorganic & medicinal chemistry letters, May-01, Volume: 24, Issue:9
Synthesis of xanthone derivatives based on α-mangostin and their biological evaluation for anti-cancer agents.
AID1723635Antibacterial activity against Pseudomonas aeruginosa2020Bioorganic & medicinal chemistry letters, 10-15, Volume: 30, Issue:20
Modified tetra-oxygenated xanthones analogues as anti-MRSA and P. aeruginosa agent and their synergism with vancomycin.
AID399163Antifungal activity against Drechslera oryzae at 1000 ppm after 168 hrs at 24 hrs intervals1997Journal of natural products, May, Volume: 60, Issue:5
Evaluation of the antifungal activity of natural xanthones from Garcinia mangostana and their synthetic derivatives.
AID398908Antifungal activity against Alternaria tenuis at 100 ppm after 168 hrs at 24 hrs intervals1997Journal of natural products, May, Volume: 60, Issue:5
Evaluation of the antifungal activity of natural xanthones from Garcinia mangostana and their synthetic derivatives.
AID399167Antifungal activity against Fusarium oxysporum vasinfectum at 1000 ppm after 144 hrs at 24 hrs intervals1997Journal of natural products, May, Volume: 60, Issue:5
Evaluation of the antifungal activity of natural xanthones from Garcinia mangostana and their synthetic derivatives.
AID1525036Cytotoxicity in human HT-29 cells incubated for 72 hrs by MTT assay2019Journal of natural products, 05-24, Volume: 82, Issue:5
Tetrandraxanthones A-I, Prenylated and Geranylated Xanthones from the Stem Bark of Garcinia tetrandra.
AID1723638Synergistic antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC 43300 in presence of vancomycin2020Bioorganic & medicinal chemistry letters, 10-15, Volume: 30, Issue:20
Modified tetra-oxygenated xanthones analogues as anti-MRSA and P. aeruginosa agent and their synergism with vancomycin.
AID1723634Antibacterial activity against Shigella sonnei2020Bioorganic & medicinal chemistry letters, 10-15, Volume: 30, Issue:20
Modified tetra-oxygenated xanthones analogues as anti-MRSA and P. aeruginosa agent and their synergism with vancomycin.
AID1140148Cytotoxicity against human SW620 cells assessed as inhibition of cell proliferation after 48 hrs by XTT assay2014Bioorganic & medicinal chemistry letters, May-01, Volume: 24, Issue:9
Synthesis of xanthone derivatives based on α-mangostin and their biological evaluation for anti-cancer agents.
AID1525033Cytotoxicity in human HeLaS3 cells incubated for 72 hrs by MTT assay2019Journal of natural products, 05-24, Volume: 82, Issue:5
Tetrandraxanthones A-I, Prenylated and Geranylated Xanthones from the Stem Bark of Garcinia tetrandra.
AID468109Cytotoxicity against human HT-29 cells2009Journal of natural products, Nov, Volume: 72, Issue:11
Cytotoxic xanthone constituents of the stem bark of Garcinia mangostana (mangosteen).
AID1723641Synergistic antibacterial activity against Pseudomonas aeruginosa assessed as fractional inhibitory concentration index in presence of vancomycin2020Bioorganic & medicinal chemistry letters, 10-15, Volume: 30, Issue:20
Modified tetra-oxygenated xanthones analogues as anti-MRSA and P. aeruginosa agent and their synergism with vancomycin.
AID1140150Cytotoxicity against human MDA-MB-231 cells assessed as inhibition of cell proliferation after 48 hrs by XTT assay2014Bioorganic & medicinal chemistry letters, May-01, Volume: 24, Issue:9
Synthesis of xanthone derivatives based on α-mangostin and their biological evaluation for anti-cancer agents.
AID1723640Synergistic antibacterial activity against Pseudomonas aeruginosa in presence of vancomycin2020Bioorganic & medicinal chemistry letters, 10-15, Volume: 30, Issue:20
Modified tetra-oxygenated xanthones analogues as anti-MRSA and P. aeruginosa agent and their synergism with vancomycin.
AID1140151Cytotoxicity against mouse B16F10 cells assessed as inhibition of cell proliferation after 48 hrs by XTT assay2014Bioorganic & medicinal chemistry letters, May-01, Volume: 24, Issue:9
Synthesis of xanthone derivatives based on α-mangostin and their biological evaluation for anti-cancer agents.
AID1542232Inhibition of Escherichia coli inorganic pyrophosphatase assessed as reduction in orthophosphate formation at 0.3 to 10 uM measured after 40 using pyrophosphate as substrate by malachite green dye based absorbance assay2019European journal of medicinal chemistry, Apr-01, Volume: 167Discovery of a new class of MTH1 inhibitor by X-ray crystallographic screening.
AID1723633Antibacterial activity against Salmonella typhi2020Bioorganic & medicinal chemistry letters, 10-15, Volume: 30, Issue:20
Modified tetra-oxygenated xanthones analogues as anti-MRSA and P. aeruginosa agent and their synergism with vancomycin.
AID398906Antifungal activity against Alternaria tenuis at 1 ppm after 168 hrs at 24 hrs intervals1997Journal of natural products, May, Volume: 60, Issue:5
Evaluation of the antifungal activity of natural xanthones from Garcinia mangostana and their synthetic derivatives.
AID1723637Induction of morphological changes in Pseudomonas aeruginosa assessed as cell deformation incubated for 24 hrs by scanning electron microscopic method2020Bioorganic & medicinal chemistry letters, 10-15, Volume: 30, Issue:20
Modified tetra-oxygenated xanthones analogues as anti-MRSA and P. aeruginosa agent and their synergism with vancomycin.
AID1542231Inhibition of recombinant C-terminal 6xHis-tagged MTH1 (3 to 156 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) cells using dGTP as substrate measured after 30 mins by malachite green dye based inorganic phosphatase coupled absorbance 2019European journal of medicinal chemistry, Apr-01, Volume: 167Discovery of a new class of MTH1 inhibitor by X-ray crystallographic screening.
AID1542234Binding affinity to recombinant C-terminal 6xHis-tagged MTH1 (3 to 156 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) cells assessed as decrease in fluorescence intensity at 1 to 10 uM after 3 mins by tryptophan fluorescence spectrosco2019European journal of medicinal chemistry, Apr-01, Volume: 167Discovery of a new class of MTH1 inhibitor by X-ray crystallographic screening.
AID399165Antifungal activity against Fusarium oxysporum vasinfectum at 10 ppm after 144 hrs at 24 hrs intervals1997Journal of natural products, May, Volume: 60, Issue:5
Evaluation of the antifungal activity of natural xanthones from Garcinia mangostana and their synthetic derivatives.
AID1723632Antibacterial activity against vancomycin-resistant Enterococcus faecalis ATCC 512992020Bioorganic & medicinal chemistry letters, 10-15, Volume: 30, Issue:20
Modified tetra-oxygenated xanthones analogues as anti-MRSA and P. aeruginosa agent and their synergism with vancomycin.
AID468108Inhibition of p50 after 1 hr by ELISA2009Journal of natural products, Nov, Volume: 72, Issue:11
Cytotoxic xanthone constituents of the stem bark of Garcinia mangostana (mangosteen).
AID399164Antifungal activity against Fusarium oxysporum vasinfectum at 1 ppm after 144 hrs at 24 hrs intervals1997Journal of natural products, May, Volume: 60, Issue:5
Evaluation of the antifungal activity of natural xanthones from Garcinia mangostana and their synthetic derivatives.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (9)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's2 (22.22)18.2507
2000's1 (11.11)29.6817
2010's5 (55.56)24.3611
2020's1 (11.11)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other10 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
xanthone
xanthone : The parent compound of the xanthone class consisting of xanthene bearing a single oxo substituent at position 9.		2.420xanthonesinsecticide
xanthenes
Xanthenes: Compounds with three aromatic rings in linear arrangement with an OXYGEN in the center ring.		1.9910xanthene
vancomycin
Vancomycin: Antibacterial obtained from Streptomyces orientalis. It is a glycopeptide related to RISTOCETIN that inhibits bacterial cell wall assembly and is toxic to kidneys and the inner ear.. vancomycin : A complex glycopeptide from Streptomyces orientalis. It inhibits a specific step in the synthesis of the peptidoglycan layer in the Gram-positive bacteria Staphylococcus aureus and Clostridium difficile.		2.2510glycopeptideantibacterial drug;
antimicrobial agent;
bacterial metabolite
camptothecin
NSC 100880: carboxylate (opened lactone) form of camptothecin; RN refers to (S)-isomer; structure given in first source		2.0510delta-lactone;
pyranoindolizinoquinoline;
quinoline alkaloid;
tertiary alcohol		antineoplastic agent;
EC 5.99.1.2 (DNA topoisomerase) inhibitor;
genotoxin;
plant metabolite
rocaglamide
rocaglamide: RN refers to (1alpha,2alpha,3beta,3abeta,8bbeta)-isomer; isolated from stems of Aglaia elliptifolia; structure given in first source. rocaglamide : An organic heterotricyclic compound that is 2,3,3a,8b-tetrahydro-1H-benzo[b]cyclopenta[d]furan substituted by hydroxy groups at positions 1 and 8b, methoxy groups at positions 6 and 8, a 4-methoxyphenyl group at position 3a, a phenyl group at position 3 and a N,N-dimethylcarbamoyl group at position 1. Isolated from Aglaia odorata and Aglaia duperreana, it exhibits antineoplastic activity.		2.0510monocarboxylic acid amide;
monomethoxybenzene;
organic heterotricyclic compound		antileishmanial agent;
antineoplastic agent;
metabolite
8-deoxygartanin
8-deoxygartanin: a butyrylcholinesterase inhibitor; isolated from Garcinia mangostana; structure in first source		2.7930xanthones
euxanthone
euxanthone : A member of the class of xanthones that is 9H-xanthene substituted by hydroxy group at positions 1 and 7 and an oxo group at position 9. It has been isolated from Cratoxylum cochinchinense.		2.2110phenols;
xanthones		metabolite;
plant metabolite
gartanin
gartanin : A member of the class of xanthones that is 9H-xanthen-9-one substituted by hydroxy groups at positions 1, 3, 5 and 8 and prenyl groups at positions 2 and 4.		2.4220polyphenol;
xanthones		antineoplastic agent;
plant metabolite
gentisein
gentisein: isolated from the methanol extract of the herb of Hypericum annulatum; structure in first source. gentisein : A member of the class of xanthones that is 9H-xanthen-9-one substituted by hydroxy groups at positions 1, 3 and 7.		2.2110polyphenol;
xanthones		plant metabolite
3-hydroxyblancoxanthone
3-hydroxyblancoxanthone: from the root of Calophyllum blancoi; structure in first source		2.2110pyranoxanthones
mangiferin
shamimin: isolated from the leaves of Bombax ceiba; structure in first source		2.2110C-glycosyl compound;
xanthones		anti-inflammatory agent;
antioxidant;
hypoglycemic agent;
plant metabolite
mangostin
mangostin: xanthone from rind of Garcinia mangostana Linn. fruit. alpha-mangostin : A member of the class of xanthones that is 9H-xanthene substituted by hydroxy group at positions 1, 3 and 6, a methoxy group at position 7, an oxo group at position 9 and prenyl groups at positions 2 and 8. Isolated from the stems of Cratoxylum cochinchinense, it exhibits antioxidant, antimicrobial and antitumour activities.		3.5780aromatic ether;
phenols;
xanthones		antimicrobial agent;
antineoplastic agent;
antioxidant;
plant metabolite
norathyriol
norathyriol: from Gentinanaceae; has vasorelaxing action on rat thoracic aorta; structure given in first source. norathyriol : A member of the class of xanthones that is 9H-xanthen-9-one substituted by hydroxy groups at positions 1, 3, 6 and 7. Isolated from Garcinia mangostana and Maclura pomifera, it exhibits inhibitory activity against protein kinase C.		2.9130polyphenol;
xanthones		antineoplastic agent;
EC 2.7.11.13 (protein kinase C) inhibitor;
plant metabolite
gamma-mangostin
gamma-mangostin : A member of the class of xanthones that is 9H-xanthene substituted by hydroxy group at positions 1, 3, 6 and 7, an oxo group at position 9 and prenyl groups at positions 2 and 8. Isolated from the stems of Cratoxylum cochinchinense, it exhibits antitumour activity.		2.9940phenols;
xanthones		antineoplastic agent;
plant metabolite;
protein kinase inhibitor
1,3,5,6-tetrahydroxyxanthone
1,3,5,6-tetrahydroxyxanthone: from roots of Cudrania cochinchinensis		2.2110
1,3,7-trihydroxy-2-(3-methylbut-2-enyl)-xanthone
1,3,7-trihydroxy-2-(3-methylbut-2-enyl)-xanthone: from stems of Kielmeyera coriacea; structure in first source		2.2110
beta-Mangostin
[no description available]		2.5120xanthones
9-Hydroxycalabaxanthone
[no description available]		2.7930xanthones
rubraxanthone
rubraxanthone: RN given for (E)-isomer; inhibits platelet-activating factor; isolated from Garcinia parvifolia; structure in first source. rubraxanthone : A member of the class of xanthones that is 9H-xanthen-9-one substituted by hydroxy groups at positions 3, 6 and 8, a geranyl group at position 1 and a methoxy group at position 2. Isolated from Mesua and Garcinia dioica, it exhibits antibacterial and cytotoxic activities.		2.2110aromatic ether;
polyphenol;
xanthones		antibacterial agent;
antineoplastic agent;
metabolite
3,4,5,6-tetrahydroxyxanthone
[no description available]		2.2110
garcinone c
garcinone C: an acetylcholinesterase inhibitor; isolated from Garcinia mangostana; structure in first source		2.5420xanthones
ent-crizotinib
ent-crizotinib : A 3-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(piperidin-4-yl)pyrazol-4-yl]pyridin-2-amine that is the (S)-enantiomer of crizotinib.		2.21103-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(piperidin-4-yl)pyrazol-4-yl]pyridin-2-amine
deoxyguanosine triphosphate
[no description available]		2.2110deoxyguanosine phosphate;
guanyl deoxyribonucleotide;
purine 2'-deoxyribonucleoside 5'-triphosphate		Arabidopsis thaliana metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite
ConditionIndicatedRelationship StrengthStudiesTrials
Benign Neoplasms
[description not available]		02.110
Neoplasms
New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.		02.110