| ID Source | ID |
|---|---|
| PubMed CID | 6439222 |
| CHEMBL ID | 57358 |
| SCHEMBL ID | 636264 |
| SCHEMBL ID | 636263 |
| MeSH ID | M0185046 |
| Synonym |
|---|
| bi-l 239 |
| phenol, 4-(2-(4-fluorophenyl)ethenyl)-2,6-dimethyl-, (e)- |
| 125722-16-9 |
| 2,6-dimethyl-4-(2-(4-fluorophenyl)ethenyl)phenol |
| bi-l-239 xx |
| enofelast |
| enofelast (usan/inn) |
| D04002 |
| 127035-60-3 |
| CHEMBL57358 , |
| bi-l-239 |
| bdbm50012806 |
| 4-[2-(4-fluoro-phenyl)-vinyl]-2,6-dimethyl-phenol |
| 4-[(e)-2-(4-fluorophenyl)ethenyl]-2,6-dimethylphenol |
| phenol, 4-(2-(4-fluorophenyl)ethenyl)-2,6-dimethyl-, (e) |
| enofelast [usan:inn] |
| (e)-4'-fluoro-3,5-dimethyl-4-stilbenol |
| 3t93ts0430 , |
| unii-3t93ts0430 |
| enofelast [inn] |
| enofelast [usan] |
| SCHEMBL636264 |
| SCHEMBL636263 |
| Q27258011 |
| (e)-4-(4-fluorostyryl)-2,6-dimethylphenol |
| AKOS040747976 |
| Protein | Taxonomy | Measurement | Average | Min (ref.) | Avg (ref.) | Max (ref.) | Bioassay(s) |
|---|---|---|---|---|---|---|---|
| Polyunsaturated fatty acid 5-lipoxygenase | Homo sapiens (human) | IC50 (µMol) | 0.1200 | 0.0001 | 1.6847 | 9.3200 | AID6718 |
| Prostaglandin G/H synthase 1 | Homo sapiens (human) | IC50 (µMol) | 1.3000 | 0.0002 | 1.5574 | 10.0000 | AID160844 |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | IC50 (µMol) | 1.3000 | 0.0001 | 0.9950 | 10.0000 | AID160844 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] | |||||||
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID6718 | Inhibition of human neutrophil 5-lipoxygenase | 1990 | Journal of medicinal chemistry, Jul, Volume: 33, Issue:7 | Effect of structure on potency and selectivity in 2,6-disubstituted 4-(2-arylethenyl)phenol lipoxygenase inhibitors. |
| AID160844 | Inhibition of human platelet Prostaglandin G/H synthase | 1990 | Journal of medicinal chemistry, Jul, Volume: 33, Issue:7 | Effect of structure on potency and selectivity in 2,6-disubstituted 4-(2-arylethenyl)phenol lipoxygenase inhibitors. |
| AID76335 | Inhibition of antigen-induced leukotriene-mediated bronchoconstriction in conscious guinea pig at the dose of 30mg/Kg, ip. | 1990 | Journal of medicinal chemistry, Jul, Volume: 33, Issue:7 | Effect of structure on potency and selectivity in 2,6-disubstituted 4-(2-arylethenyl)phenol lipoxygenase inhibitors. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 5 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||