| Assay ID | Title | Year | Journal | Article |
|---|
| AID107329 | Inhibition of Matrix metalloprotease-2 | 2001 | Bioorganic & medicinal chemistry letters, Oct-08, Volume: 11, Issue:19
| Asymmetric synthesis of BB-3497--a potent peptide deformylase inhibitor. |
| AID207864 | Antibacterial activity against Staphylococcus capitis. | 2003 | Bioorganic & medicinal chemistry letters, Aug-18, Volume: 13, Issue:16
| Structure--activity relationships of the peptide deformylase inhibitor BB-3497: modification of the P2' and P3' side chains. |
| AID107671 | Inhibition of Matrix metalloprotease-3 | 2001 | Bioorganic & medicinal chemistry letters, Oct-08, Volume: 11, Issue:19
| Asymmetric synthesis of BB-3497--a potent peptide deformylase inhibitor. |
| AID107838 | Inhibition of Matrix metalloprotease-7 | 2001 | Bioorganic & medicinal chemistry letters, Oct-08, Volume: 11, Issue:19
| Asymmetric synthesis of BB-3497--a potent peptide deformylase inhibitor. |
| AID83653 | Minimum inhibitory concentration required for primary screening against in-house strain of Haemophilus influenzae tested in vitro; Range- 0.06-8 | 2004 | Bioorganic & medicinal chemistry letters, Jan-05, Volume: 14, Issue:1
| Peptide deformylase inhibitors with activity against respiratory tract pathogens. |
| AID239451 | Inhibitory effect against Escherichia coli peptide deformylase (PDF) by AAP assay | 2004 | Journal of medicinal chemistry, Sep-23, Volume: 47, Issue:20
| Macrocyclic inhibitors for peptide deformylase: a structure-activity relationship study of the ring size. |
| AID156925 | Inhibition concentration against Escherichia coli peptide deformylase. | 2003 | Bioorganic & medicinal chemistry letters, Aug-18, Volume: 13, Issue:16
| Structure--activity relationships of the peptide deformylase inhibitor BB-3497: modification of the P2' and P3' side chains. |
| AID207866 | Minimum inhibitory concentration required for primary screening against in-house strain of Staphylococcus capitis tested in vitro | 2004 | Bioorganic & medicinal chemistry letters, Jan-05, Volume: 14, Issue:1
| Peptide deformylase inhibitors with activity against respiratory tract pathogens. |
| AID125109 | Minimum inhibitory concentration required for primary screening against in-house strain of Moraxella catarrhalis tested in vitro; Range = 0.015-0.12 | 2004 | Bioorganic & medicinal chemistry letters, Jan-05, Volume: 14, Issue:1
| Peptide deformylase inhibitors with activity against respiratory tract pathogens. |
| AID69779 | Antibacterial activity against Escherichia coli. | 2003 | Bioorganic & medicinal chemistry letters, Aug-18, Volume: 13, Issue:16
| Structure--activity relationships of the peptide deformylase inhibitor BB-3497: modification of the P2' and P3' side chains. |
| AID207865 | Compound was evaluated for antibacterial activity against Staphylococcus capitis | 2002 | Bioorganic & medicinal chemistry letters, Dec-16, Volume: 12, Issue:24
| Structure-activity relationships of the peptide deformylase inhibitor BB-3497: modification of the metal binding group. |
| AID156924 | Inhibition against Escherichia coli peptide deformylase | 2003 | Bioorganic & medicinal chemistry letters, Aug-18, Volume: 13, Issue:16
| Structure-activity relationships of the peptide deformylase inhibitor BB-3497: modification of the methylene spacer and the P1' side chain. |
| AID239459 | Inhibitory effect against Escherichia coli peptide deformylase (PDF) by DPPI assay | 2004 | Journal of medicinal chemistry, Sep-23, Volume: 47, Issue:20
| Macrocyclic inhibitors for peptide deformylase: a structure-activity relationship study of the ring size. |
| AID238031 | The inhibition constant was measured against Escherichia coli PDF (Peptide deformylase) by diluting a preformed EI* complex into a assay buffer containing f-Met-Lys-AMC and DPPI | 2004 | Journal of medicinal chemistry, Sep-23, Volume: 47, Issue:20
| Macrocyclic inhibitors for peptide deformylase: a structure-activity relationship study of the ring size. |
| AID238030 | Inhibition constant against Escherichia coli Peptide deformylase (PDF) | 2004 | Journal of medicinal chemistry, Sep-23, Volume: 47, Issue:20
| Macrocyclic inhibitors for peptide deformylase: a structure-activity relationship study of the ring size. |
| AID69652 | Minimum inhibitory concentration required for primary screening against in-house strain of Escherichia coli tested in vitro | 2004 | Bioorganic & medicinal chemistry letters, Jan-05, Volume: 14, Issue:1
| Peptide deformylase inhibitors with activity against respiratory tract pathogens. |
| AID157060 | Inhibitory activity against Escherichia coli peptide deformylase (PDF) Nickel containing enzyme | 2004 | Bioorganic & medicinal chemistry letters, Jan-05, Volume: 14, Issue:1
| Peptide deformylase inhibitors with activity against respiratory tract pathogens. |
| AID207863 | Antibacterial activity against Staphylococcus capitis | 2003 | Bioorganic & medicinal chemistry letters, Aug-18, Volume: 13, Issue:16
| Structure-activity relationships of the peptide deformylase inhibitor BB-3497: modification of the methylene spacer and the P1' side chain. |
| AID1890841 | Antimycobacterial activity against Mycobacterium tuberculosis H37Rv assessed as inhibition of bacterial growth incubated for 8 days | 2022 | Bioorganic & medicinal chemistry letters, 05-15, Volume: 64 | Design, synthesis and antibacterial activity against pathogenic mycobacteria of conjugated hydroxamic acids, hydrazides and O-alkyl/O-acyl protected hydroxamic derivatives. |
| AID1890850 | Inhibition of Mycobacterium tuberculosis H37Rv PDF expressed in Escherichia coli using N-formyl-methionine-alanine-serine as substrate incubated for 2.5 mins by fluorescence based microplate reader analysis | 2022 | Bioorganic & medicinal chemistry letters, 05-15, Volume: 64 | Design, synthesis and antibacterial activity against pathogenic mycobacteria of conjugated hydroxamic acids, hydrazides and O-alkyl/O-acyl protected hydroxamic derivatives. |
| AID208636 | Minimum inhibitory concentration required for primary screening against in-house strain of Streptococcus pneumoniae tested in vitro; Range- 2->8 | 2004 | Bioorganic & medicinal chemistry letters, Jan-05, Volume: 14, Issue:1
| Peptide deformylase inhibitors with activity against respiratory tract pathogens. |
| AID69778 | Antibacterial activity against Escherichia coli | 2003 | Bioorganic & medicinal chemistry letters, Aug-18, Volume: 13, Issue:16
| Structure-activity relationships of the peptide deformylase inhibitor BB-3497: modification of the methylene spacer and the P1' side chain. |
| AID38855 | Compound was tested for its inhibitory activity against Angiotensin I converting enzyme | 2001 | Bioorganic & medicinal chemistry letters, Oct-08, Volume: 11, Issue:19
| Asymmetric synthesis of BB-3497--a potent peptide deformylase inhibitor. |
| AID156922 | Antibacterial activity against Escherichia coli Peptide deformylase. Ni | 2001 | Bioorganic & medicinal chemistry letters, Oct-08, Volume: 11, Issue:19
| Asymmetric synthesis of BB-3497--a potent peptide deformylase inhibitor. |
| AID70091 | Compound was evaluated for antibacterial activity against Escherichia coli | 2002 | Bioorganic & medicinal chemistry letters, Dec-16, Volume: 12, Issue:24
| Structure-activity relationships of the peptide deformylase inhibitor BB-3497: modification of the metal binding group. |
| AID156923 | Compound was evaluated for inhibition of peptide deformylase, PDF.Ni of Escherichia coli | 2002 | Bioorganic & medicinal chemistry letters, Dec-16, Volume: 12, Issue:24
| Structure-activity relationships of the peptide deformylase inhibitor BB-3497: modification of the metal binding group. |
| AID147394 | The compound was evaluated in vitro for the inhibition of Neutral endopeptidase | 2001 | Bioorganic & medicinal chemistry letters, Oct-08, Volume: 11, Issue:19
| Asymmetric synthesis of BB-3497--a potent peptide deformylase inhibitor. |
| AID109226 | Inhibition of human Matrix metalloprotease-1 | 2001 | Bioorganic & medicinal chemistry letters, Oct-08, Volume: 11, Issue:19
| Asymmetric synthesis of BB-3497--a potent peptide deformylase inhibitor. |
| AID977608 | Experimentally measured binding affinity data (IC50) for protein-ligand complexes derived from PDB | 2001 | Antimicrobial agents and chemotherapy, Feb, Volume: 45, Issue:2
| Antibiotic activity and characterization of BB-3497, a novel peptide deformylase inhibitor. |
| AID1811 | Experimentally measured binding affinity data derived from PDB | 2001 | Antimicrobial agents and chemotherapy, Feb, Volume: 45, Issue:2
| Antibiotic activity and characterization of BB-3497, a novel peptide deformylase inhibitor. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |