Assay ID | Title | Year | Journal | Article |
AID727894 | Cytotoxicity against mouse theophylline-induced B16-4A5 cells assessed as cell viability at 1 uM after 72 hrs by WST8 assay relative to control | 2013 | Bioorganic & medicinal chemistry, Mar-01, Volume: 21, Issue:5
| Alkaloids from Sri Lankan curry-leaf (Murraya koenigii) display melanogenesis inhibitory activity: structures of karapinchamines A and B. |
AID727898 | Inhibition of theophylline-induced melanogenesis in mouse B16-4A5 cells after 72 hrs by spectrophotometric analysis relative to control | 2013 | Bioorganic & medicinal chemistry, Mar-01, Volume: 21, Issue:5
| Alkaloids from Sri Lankan curry-leaf (Murraya koenigii) display melanogenesis inhibitory activity: structures of karapinchamines A and B. |
AID727901 | Inhibition of theophylline-induced melanogenesis in mouse B16-4A5 cells at 1 uM after 72 hrs by spectrophotometric analysis relative to control | 2013 | Bioorganic & medicinal chemistry, Mar-01, Volume: 21, Issue:5
| Alkaloids from Sri Lankan curry-leaf (Murraya koenigii) display melanogenesis inhibitory activity: structures of karapinchamines A and B. |
AID1315294 | Half life in rat liver microsomes in presence of NADPH by HPLC analysis | 2016 | Journal of natural products, 05-27, Volume: 79, Issue:5
| Naturally Occurring Carbazole Alkaloids from Murraya koenigii as Potential Antidiabetic Agents. |
AID1315289 | Activation of Akt-dependent signalling pathway in rat L6 myotubes assessed as increase in myc-tagged GLUT4-mediated 2-[3H]-deoxyglucose uptake at 25 uM incubated for 16 hrs measured for 5 mins by beta scintillation counting relative to control | 2016 | Journal of natural products, 05-27, Volume: 79, Issue:5
| Naturally Occurring Carbazole Alkaloids from Murraya koenigii as Potential Antidiabetic Agents. |
AID1871701 | Antiproliferative activity against human HepG2 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay | 2022 | European journal of medicinal chemistry, Feb-05, Volume: 229 | Current status of carbazole hybrids as anticancer agents. |
AID727886 | Inhibition of mushroom tyrosinase using L-DOPA as substrate after at 100 uM after 5 mins relative to control | 2013 | Bioorganic & medicinal chemistry, Mar-01, Volume: 21, Issue:5
| Alkaloids from Sri Lankan curry-leaf (Murraya koenigii) display melanogenesis inhibitory activity: structures of karapinchamines A and B. |
AID1871700 | Antiproliferative activity against human OVCAR-3 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay | 2022 | European journal of medicinal chemistry, Feb-05, Volume: 229 | Current status of carbazole hybrids as anticancer agents. |
AID1315292 | Activation of Akt-dependent signalling pathway in rat L6 myotubes assessed as induction of myc-tagged GLUT4 translocation to cell surface at 25 uM incubated for 16 hrs by O-phenylenediamide based colorimetric assay relative to control | 2016 | Journal of natural products, 05-27, Volume: 79, Issue:5
| Naturally Occurring Carbazole Alkaloids from Murraya koenigii as Potential Antidiabetic Agents. |
AID1315288 | Activation of Akt-dependent signalling pathway in rat L6 myotubes assessed as increase in insulin-stimulated myc-tagged GLUT4-mediated 2-[3H]-deoxyglucose uptake at 25 uM incubated for 16 hrs followed by insulin stimulation for 20 mins measured for 5 mins | 2016 | Journal of natural products, 05-27, Volume: 79, Issue:5
| Naturally Occurring Carbazole Alkaloids from Murraya koenigii as Potential Antidiabetic Agents. |
AID1871699 | Antiproliferative activity against human PA-1 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay | 2022 | European journal of medicinal chemistry, Feb-05, Volume: 229 | Current status of carbazole hybrids as anticancer agents. |
AID727893 | Cytotoxicity against mouse theophylline-induced B16-4A5 cells assessed as cell viability at 3 uM after 72 hrs by WST8 assay relative to control | 2013 | Bioorganic & medicinal chemistry, Mar-01, Volume: 21, Issue:5
| Alkaloids from Sri Lankan curry-leaf (Murraya koenigii) display melanogenesis inhibitory activity: structures of karapinchamines A and B. |
AID1315295 | Antidiabetic activity in overnight fasted STZ-induced albino Sprague-Dawley rat diabetic model assessed as decrease in blood glucose level at 100 mg/kg, po measured up to 5 hrs | 2016 | Journal of natural products, 05-27, Volume: 79, Issue:5
| Naturally Occurring Carbazole Alkaloids from Murraya koenigii as Potential Antidiabetic Agents. |
AID1871702 | Antiproliferative activity against human DU-145 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay | 2022 | European journal of medicinal chemistry, Feb-05, Volume: 229 | Current status of carbazole hybrids as anticancer agents. |
AID1315310 | Cmax in Sprague-Dawley rat plasma at 100 mg/kg, po administered as single dose measured up to 48 hrs post dose by LC-MS/MS analysis | 2016 | Journal of natural products, 05-27, Volume: 79, Issue:5
| Naturally Occurring Carbazole Alkaloids from Murraya koenigii as Potential Antidiabetic Agents. |
AID727888 | Inhibition of mushroom tyrosinase using L-DOPA as substrate after at 10 uM after 5 mins relative to control | 2013 | Bioorganic & medicinal chemistry, Mar-01, Volume: 21, Issue:5
| Alkaloids from Sri Lankan curry-leaf (Murraya koenigii) display melanogenesis inhibitory activity: structures of karapinchamines A and B. |
AID1315309 | AUC (0 to infinity) in Sprague-Dawley rat plasma at 100 mg/kg, po administered as single dose measured up to 48 hrs post dose by LC-MS/MS analysis | 2016 | Journal of natural products, 05-27, Volume: 79, Issue:5
| Naturally Occurring Carbazole Alkaloids from Murraya koenigii as Potential Antidiabetic Agents. |
AID1333884 | Inhibition of pancreatic lipase (unknown origin) | 2017 | Bioorganic & medicinal chemistry, 01-15, Volume: 25, Issue:2
| Synthesis, evaluation and molecular modelling studies of 2-(carbazol-3-yl)-2-oxoacetamide analogues as a new class of potential pancreatic lipase inhibitors. |
AID1315290 | Activation of Akt-dependent signalling pathway in rat L6 myotubes assessed as increase in myc-tagged GLUT4-mediated 2-[3H]-deoxyglucose uptake incubated for 16 hrs measured for 5 mins by beta scintillation counting | 2016 | Journal of natural products, 05-27, Volume: 79, Issue:5
| Naturally Occurring Carbazole Alkaloids from Murraya koenigii as Potential Antidiabetic Agents. |
AID1871703 | Antiproliferative activity against human HCT-116 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay | 2022 | European journal of medicinal chemistry, Feb-05, Volume: 229 | Current status of carbazole hybrids as anticancer agents. |
AID727890 | Inhibition of mushroom tyrosinase using L-DOPA as substrate after at 1 uM after 5 mins relative to control | 2013 | Bioorganic & medicinal chemistry, Mar-01, Volume: 21, Issue:5
| Alkaloids from Sri Lankan curry-leaf (Murraya koenigii) display melanogenesis inhibitory activity: structures of karapinchamines A and B. |
AID727902 | Inhibition of theophylline-induced melanogenesis in mouse B16-4A5 cells at 3 uM after 72 hrs by spectrophotometric analysis relative to control | 2013 | Bioorganic & medicinal chemistry, Mar-01, Volume: 21, Issue:5
| Alkaloids from Sri Lankan curry-leaf (Murraya koenigii) display melanogenesis inhibitory activity: structures of karapinchamines A and B. |
AID727887 | Inhibition of mushroom tyrosinase using L-DOPA as substrate after at 30 uM after 5 mins relative to control | 2013 | Bioorganic & medicinal chemistry, Mar-01, Volume: 21, Issue:5
| Alkaloids from Sri Lankan curry-leaf (Murraya koenigii) display melanogenesis inhibitory activity: structures of karapinchamines A and B. |
AID727891 | Cytotoxicity against mouse theophylline-induced B16-4A5 cells assessed as cell viability at 10 uM after 72 hrs by WST8 assay relative to control | 2013 | Bioorganic & medicinal chemistry, Mar-01, Volume: 21, Issue:5
| Alkaloids from Sri Lankan curry-leaf (Murraya koenigii) display melanogenesis inhibitory activity: structures of karapinchamines A and B. |
AID1315296 | Antidiabetic activity in overnight fasted STZ-induced albino Sprague-Dawley rat diabetic model assessed as decrease in blood glucose level at 100 mg/kg, po measured up to 24 hrs | 2016 | Journal of natural products, 05-27, Volume: 79, Issue:5
| Naturally Occurring Carbazole Alkaloids from Murraya koenigii as Potential Antidiabetic Agents. |
AID727892 | Cytotoxicity against mouse theophylline-induced B16-4A5 cells assessed as cell viability at 30 uM after 72 hrs by WST8 assay relative to control | 2013 | Bioorganic & medicinal chemistry, Mar-01, Volume: 21, Issue:5
| Alkaloids from Sri Lankan curry-leaf (Murraya koenigii) display melanogenesis inhibitory activity: structures of karapinchamines A and B. |
AID1315307 | Metabolic stability in rat liver microsomes assessed as drug degradation rate constant incubated for 90 mins by HPLC analysis | 2016 | Journal of natural products, 05-27, Volume: 79, Issue:5
| Naturally Occurring Carbazole Alkaloids from Murraya koenigii as Potential Antidiabetic Agents. |
AID1315311 | Tmax in Sprague-Dawley rat plasma at 100 mg/kg, po administered as single dose by LC-MS/MS analysis | 2016 | Journal of natural products, 05-27, Volume: 79, Issue:5
| Naturally Occurring Carbazole Alkaloids from Murraya koenigii as Potential Antidiabetic Agents. |
AID727899 | Inhibition of theophylline-induced melanogenesis in mouse B16-4A5 cells at 10 uM after 72 hrs by spectrophotometric analysis relative to control | 2013 | Bioorganic & medicinal chemistry, Mar-01, Volume: 21, Issue:5
| Alkaloids from Sri Lankan curry-leaf (Murraya koenigii) display melanogenesis inhibitory activity: structures of karapinchamines A and B. |
AID727889 | Inhibition of mushroom tyrosinase using L-DOPA as substrate after at 3 uM after 5 mins relative to control | 2013 | Bioorganic & medicinal chemistry, Mar-01, Volume: 21, Issue:5
| Alkaloids from Sri Lankan curry-leaf (Murraya koenigii) display melanogenesis inhibitory activity: structures of karapinchamines A and B. |
AID1871704 | Antiproliferative activity against human HeLa cells assessed as cell growth inhibition measured after 48 hrs by MTT assay | 2022 | European journal of medicinal chemistry, Feb-05, Volume: 229 | Current status of carbazole hybrids as anticancer agents. |
AID1315293 | Metabolic stability in rat liver microsomes assessed as parent compound remaining after 90 mins in presence of NADPH by HPLC analysis | 2016 | Journal of natural products, 05-27, Volume: 79, Issue:5
| Naturally Occurring Carbazole Alkaloids from Murraya koenigii as Potential Antidiabetic Agents. |
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |