| Assay ID | Title | Year | Journal | Article |
|---|
| AID1346381 | Human OX1 receptor (Orexin receptors) | 2010 | Molecular pharmacology, Jul, Volume: 78, Issue:1
| Mapping the binding pocket of dual antagonist almorexant to human orexin 1 and orexin 2 receptors: comparison with the selective OX1 antagonist SB-674042 and the selective OX2 antagonist N-ethyl-2-[(6-methoxy-pyridin-3-yl)-(toluene-2-sulfonyl)-amino]-N-py |
| AID1346418 | Human OX2 receptor (Orexin receptors) | 2013 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 23, Issue:17
| Selective orexin receptor antagonists. |
| AID1346381 | Human OX1 receptor (Orexin receptors) | 2004 | British journal of pharmacology, Jan, Volume: 141, Issue:2
| Characterisation of the binding of [3H]-SB-674042, a novel nonpeptide antagonist, to the human orexin-1 receptor. |
| AID1346381 | Human OX1 receptor (Orexin receptors) | 2009 | Molecular pharmacology, Sep, Volume: 76, Issue:3
| Biochemical and electrophysiological characterization of almorexant, a dual orexin 1 receptor (OX1)/orexin 2 receptor (OX2) antagonist: comparison with selective OX1 and OX2 antagonists. |
| AID1296008 | Cytotoxic Profiling of Annotated Libraries Using Quantitative High-Throughput Screening | 2020 | SLAS discovery : advancing life sciences R & D, 01, Volume: 25, Issue:1
| Cytotoxic Profiling of Annotated and Diverse Chemical Libraries Using Quantitative High-Throughput Screening. |
| AID1347160 | Primary screen NINDS Rhodamine qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1347159 | Primary screen GU Rhodamine qHTS for Zika virus inhibitors: Unlinked NS2B-NS3 protease assay | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1346986 | P-glycoprotein substrates identified in KB-3-1 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5
| A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
| AID1346987 | P-glycoprotein substrates identified in KB-8-5-11 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5
| A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
| AID765089 | Binding affinity to orexin receptor 1 (unknown origin) | 2013 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 23, Issue:17
| Selective orexin receptor antagonists. |
| AID1724830 | Displacement of [3H]-EMPA from human orexin 2 receptor expressed in CHO cells incubated for 2 hrs by whole cell radioligand binding assay | 2020 | Journal of medicinal chemistry, 10-08, Volume: 63, Issue:19
| Structure-Based Discovery of Novel Ligands for the Orexin 2 Receptor. |
| AID765090 | Binding affinity to orexin receptor 2 (unknown origin) | 2013 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 23, Issue:17
| Selective orexin receptor antagonists. |
| AID1724828 | Displacement of [3H]-SB67404 from human orexin 1 receptor expressed in CHO cells incubated for 2 hrs by whole cell radioligand binding assay | 2020 | Journal of medicinal chemistry, 10-08, Volume: 63, Issue:19
| Structure-Based Discovery of Novel Ligands for the Orexin 2 Receptor. |
| AID347748 | Selectivity for OX1 receptor over OX2 receptor | 2009 | Journal of medicinal chemistry, Feb-26, Volume: 52, Issue:4
| Biomedical application of orexin/hypocretin receptor ligands in neuroscience. |
| AID347747 | Binding affinity to OX1 receptor | 2009 | Journal of medicinal chemistry, Feb-26, Volume: 52, Issue:4
| Biomedical application of orexin/hypocretin receptor ligands in neuroscience. |
| AID1794808 | Fluorescence-based screening to identify small molecule inhibitors of Plasmodium falciparum apicoplast DNA polymerase (Pf-apPOL). | 2014 | Journal of biomolecular screening, Jul, Volume: 19, Issue:6
| A High-Throughput Assay to Identify Inhibitors of the Apicoplast DNA Polymerase from Plasmodium falciparum. |
| AID1794808 | Fluorescence-based screening to identify small molecule inhibitors of Plasmodium falciparum apicoplast DNA polymerase (Pf-apPOL). | | | |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |