bms 195614 profile

BMS 195614 : A carboxamide resulting from the formal condensation of the carboxy group of 5,5-dimethyl-8-(quinolin-3-yl)-5,6-dihydronaphthalene-2-carboxylic acid with the amino group of p-aminobenzoic acid. It is a neutral retinoic acid receptor (RAR) alpha-selective antagonist (Ki = 2.5 nM). It displays no significant effect on nuclear receptor corepressor (NCoR) binding; moderately decreases SMRT binding to RAR. It antagonizes agonist-induced coactivator (CoA) recruitment. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

ID Source	ID
PubMed CID	445091
CHEMBL ID	2385269
CHEBI ID	132571
SCHEMBL ID	6756065
MeSH ID	M0537867

Synonym
gtpl2643
4-[(5,5-dimethyl-8-quinolin-3-yl6h-naphthalene-2-carbonyl)amino]benzoic acid
cid:445091
CHEBI:132571
bms614
bms 195614
4-({[5,5-dimethyl-8-(quinolin-3-yl)-5,6-dihydronaphthalen-2-yl]carbonyl}amino)benzoic acid
bms-614
4-[[[5,6-dihydro-5,5-dimethyl-8-(3-quinolinyl)-2-naphthalenyl]carbonyl]amino]benzoic acid
253310-42-8
4-[(5,5-dimethyl-8-quinolin-3-yl-6h-naphthalene-2-carbonyl)amino]benzoic acid
bms-195614
bms195614
bms 614
bdbm36811
CHEMBL2385269
SCHEMBL6756065
182135-66-6
AKOS024457734
bms-195614, >=97% (hplc)
J-015939
NCGC00370906-01
Q27075359
4-[[[5,6-dihydro-5,5-dimethyl-8-(3-quinolinyl)-2-naphthalenyl]carbonyl]amino]-benzoicacid
NCGC00370906-03
4-(5,5-dimethyl-8-(quinolin-3-yl)-5,6-dihydronaphthalene-2-carboxamido)benzoic acid
AC-36959
HY-101259
CS-0021054
AT34290
DTXSID101123381

Role	Description
retinoic acid receptor alpha antagonist	A retinoic acid receptor antagonist that antagonises retinoic acid receptor alpha.
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Class	Description
quinolines	A class of aromatic heterocyclic compounds each of which contains a benzene ring ortho fused to carbons 2 and 3 of a pyridine ring.
benzoic acids	Any aromatic carboxylic acid that consists of benzene in which at least a single hydrogen has been substituted by a carboxy group.
secondary carboxamide	A carboxamide resulting from the formal condensation of a carboxylic acid with a primary amine; formula RC(=O)NHR(1).
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Protein	Taxonomy	Measurement	Average (µ)	Min (ref.)	Avg (ref.)	Max (ref.)	Bioassay(s)
cytochrome P450 family 3 subfamily A polypeptide 4	Homo sapiens (human)	Potency	30.1116	0.0123	7.9835	43.2770	AID1645841
G	Vesicular stomatitis virus	Potency	21.3174	0.0123	8.9648	39.8107	AID1645842
cytochrome P450 2D6	Homo sapiens (human)	Potency	37.9083	0.0010	8.3798	61.1304	AID1645840
Interferon beta	Homo sapiens (human)	Potency	21.3174	0.0033	9.1582	39.8107	AID1645842
HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)	Potency	21.3174	0.0123	8.9648	39.8107	AID1645842
Inositol hexakisphosphate kinase 1	Homo sapiens (human)	Potency	21.3174	0.0123	8.9648	39.8107	AID1645842
cytochrome P450 2C9, partial	Homo sapiens (human)	Potency	21.3174	0.0123	8.9648	39.8107	AID1645842
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Protein	Taxonomy	Measurement	Average	Min (ref.)	Avg (ref.)	Max (ref.)	Bioassay(s)
Retinoic acid receptor alpha	Homo sapiens (human)	Ki	0.0017	0.0010	0.9485	6.5000	AID1799455
Retinoic acid receptor gamma	Homo sapiens (human)	Ki	0.0017	0.0000	1.9975	10.0000	AID1799455
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Process	via Protein(s)	Taxonomy
cell surface receptor signaling pathway via JAK-STAT	Interferon beta	Homo sapiens (human)
response to exogenous dsRNA	Interferon beta	Homo sapiens (human)
B cell activation involved in immune response	Interferon beta	Homo sapiens (human)
cell surface receptor signaling pathway	Interferon beta	Homo sapiens (human)
cell surface receptor signaling pathway via JAK-STAT	Interferon beta	Homo sapiens (human)
response to virus	Interferon beta	Homo sapiens (human)
positive regulation of autophagy	Interferon beta	Homo sapiens (human)
cytokine-mediated signaling pathway	Interferon beta	Homo sapiens (human)
natural killer cell activation	Interferon beta	Homo sapiens (human)
positive regulation of peptidyl-serine phosphorylation of STAT protein	Interferon beta	Homo sapiens (human)
cellular response to interferon-beta	Interferon beta	Homo sapiens (human)
B cell proliferation	Interferon beta	Homo sapiens (human)
negative regulation of viral genome replication	Interferon beta	Homo sapiens (human)
innate immune response	Interferon beta	Homo sapiens (human)
positive regulation of innate immune response	Interferon beta	Homo sapiens (human)
regulation of MHC class I biosynthetic process	Interferon beta	Homo sapiens (human)
negative regulation of T cell differentiation	Interferon beta	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	Interferon beta	Homo sapiens (human)
defense response to virus	Interferon beta	Homo sapiens (human)
type I interferon-mediated signaling pathway	Interferon beta	Homo sapiens (human)
neuron cellular homeostasis	Interferon beta	Homo sapiens (human)
cellular response to exogenous dsRNA	Interferon beta	Homo sapiens (human)
cellular response to virus	Interferon beta	Homo sapiens (human)
negative regulation of Lewy body formation	Interferon beta	Homo sapiens (human)
negative regulation of T-helper 2 cell cytokine production	Interferon beta	Homo sapiens (human)
positive regulation of apoptotic signaling pathway	Interferon beta	Homo sapiens (human)
response to exogenous dsRNA	Interferon beta	Homo sapiens (human)
B cell differentiation	Interferon beta	Homo sapiens (human)
natural killer cell activation involved in immune response	Interferon beta	Homo sapiens (human)
adaptive immune response	Interferon beta	Homo sapiens (human)
T cell activation involved in immune response	Interferon beta	Homo sapiens (human)
humoral immune response	Interferon beta	Homo sapiens (human)
positive regulation of T cell mediated cytotoxicity	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
adaptive immune response	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
regulation of T cell anergy	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
defense response	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
immune response	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
detection of bacterium	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
regulation of interleukin-12 production	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
regulation of interleukin-6 production	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
protection from natural killer cell mediated cytotoxicity	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
innate immune response	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
regulation of dendritic cell differentiation	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
antigen processing and presentation of endogenous peptide antigen via MHC class Ib	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
ureteric bud development	Retinoic acid receptor alpha	Homo sapiens (human)
neural tube closure	Retinoic acid receptor alpha	Homo sapiens (human)
liver development	Retinoic acid receptor alpha	Homo sapiens (human)
glandular epithelial cell development	Retinoic acid receptor alpha	Homo sapiens (human)
growth plate cartilage development	Retinoic acid receptor alpha	Homo sapiens (human)
protein phosphorylation	Retinoic acid receptor alpha	Homo sapiens (human)
germ cell development	Retinoic acid receptor alpha	Homo sapiens (human)
female pregnancy	Retinoic acid receptor alpha	Homo sapiens (human)
positive regulation of cell population proliferation	Retinoic acid receptor alpha	Homo sapiens (human)
negative regulation of cell population proliferation	Retinoic acid receptor alpha	Homo sapiens (human)
negative regulation of translation	Retinoic acid receptor alpha	Homo sapiens (human)
hippocampus development	Retinoic acid receptor alpha	Homo sapiens (human)
prostate gland development	Retinoic acid receptor alpha	Homo sapiens (human)
negative regulation of granulocyte differentiation	Retinoic acid receptor alpha	Homo sapiens (human)
embryonic camera-type eye development	Retinoic acid receptor alpha	Homo sapiens (human)
regulation of myelination	Retinoic acid receptor alpha	Homo sapiens (human)
response to estradiol	Retinoic acid receptor alpha	Homo sapiens (human)
response to retinoic acid	Retinoic acid receptor alpha	Homo sapiens (human)
negative regulation of type II interferon production	Retinoic acid receptor alpha	Homo sapiens (human)
negative regulation of tumor necrosis factor production	Retinoic acid receptor alpha	Homo sapiens (human)
positive regulation of interleukin-13 production	Retinoic acid receptor alpha	Homo sapiens (human)
positive regulation of interleukin-4 production	Retinoic acid receptor alpha	Homo sapiens (human)
positive regulation of interleukin-5 production	Retinoic acid receptor alpha	Homo sapiens (human)
response to vitamin A	Retinoic acid receptor alpha	Homo sapiens (human)
response to cytokine	Retinoic acid receptor alpha	Homo sapiens (human)
multicellular organism growth	Retinoic acid receptor alpha	Homo sapiens (human)
mRNA transcription by RNA polymerase II	Retinoic acid receptor alpha	Homo sapiens (human)
regulation of apoptotic process	Retinoic acid receptor alpha	Homo sapiens (human)
apoptotic cell clearance	Retinoic acid receptor alpha	Homo sapiens (human)
response to ethanol	Retinoic acid receptor alpha	Homo sapiens (human)
positive regulation of T-helper 2 cell differentiation	Retinoic acid receptor alpha	Homo sapiens (human)
positive regulation of neuron differentiation	Retinoic acid receptor alpha	Homo sapiens (human)
positive regulation of cell cycle	Retinoic acid receptor alpha	Homo sapiens (human)
negative regulation of DNA-templated transcription	Retinoic acid receptor alpha	Homo sapiens (human)
positive regulation of DNA-templated transcription	Retinoic acid receptor alpha	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	Retinoic acid receptor alpha	Homo sapiens (human)
regulation of synaptic plasticity	Retinoic acid receptor alpha	Homo sapiens (human)
retinoic acid receptor signaling pathway	Retinoic acid receptor alpha	Homo sapiens (human)
positive regulation of binding	Retinoic acid receptor alpha	Homo sapiens (human)
ventricular cardiac muscle cell differentiation	Retinoic acid receptor alpha	Homo sapiens (human)
Sertoli cell fate commitment	Retinoic acid receptor alpha	Homo sapiens (human)
limb development	Retinoic acid receptor alpha	Homo sapiens (human)
face development	Retinoic acid receptor alpha	Homo sapiens (human)
trachea cartilage development	Retinoic acid receptor alpha	Homo sapiens (human)
chondroblast differentiation	Retinoic acid receptor alpha	Homo sapiens (human)
negative regulation of cartilage development	Retinoic acid receptor alpha	Homo sapiens (human)
cellular response to lipopolysaccharide	Retinoic acid receptor alpha	Homo sapiens (human)
cellular response to retinoic acid	Retinoic acid receptor alpha	Homo sapiens (human)
cellular response to estrogen stimulus	Retinoic acid receptor alpha	Homo sapiens (human)
regulation of hematopoietic progenitor cell differentiation	Retinoic acid receptor alpha	Homo sapiens (human)
negative regulation of miRNA transcription	Retinoic acid receptor alpha	Homo sapiens (human)
cell differentiation	Retinoic acid receptor alpha	Homo sapiens (human)
hormone-mediated signaling pathway	Retinoic acid receptor alpha	Homo sapiens (human)
negative regulation of transcription by RNA polymerase II	Retinoic acid receptor alpha	Homo sapiens (human)
negative regulation of transcription by RNA polymerase II	Retinoic acid receptor gamma	Homo sapiens (human)
neural tube closure	Retinoic acid receptor gamma	Homo sapiens (human)
glandular epithelial cell development	Retinoic acid receptor gamma	Homo sapiens (human)
growth plate cartilage chondrocyte growth	Retinoic acid receptor gamma	Homo sapiens (human)
apoptotic process	Retinoic acid receptor gamma	Homo sapiens (human)
positive regulation of cell population proliferation	Retinoic acid receptor gamma	Homo sapiens (human)
negative regulation of cell population proliferation	Retinoic acid receptor gamma	Homo sapiens (human)
regulation of cell size	Retinoic acid receptor gamma	Homo sapiens (human)
anterior/posterior pattern specification	Retinoic acid receptor gamma	Homo sapiens (human)
positive regulation of gene expression	Retinoic acid receptor gamma	Homo sapiens (human)
embryonic camera-type eye development	Retinoic acid receptor gamma	Homo sapiens (human)
regulation of myelination	Retinoic acid receptor gamma	Homo sapiens (human)
negative regulation of chondrocyte differentiation	Retinoic acid receptor gamma	Homo sapiens (human)
response to retinoic acid	Retinoic acid receptor gamma	Homo sapiens (human)
embryonic hindlimb morphogenesis	Retinoic acid receptor gamma	Homo sapiens (human)
multicellular organism growth	Retinoic acid receptor gamma	Homo sapiens (human)
positive regulation of apoptotic process	Retinoic acid receptor gamma	Homo sapiens (human)
positive regulation of programmed cell death	Retinoic acid receptor gamma	Homo sapiens (human)
regulation of myeloid cell differentiation	Retinoic acid receptor gamma	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	Retinoic acid receptor gamma	Homo sapiens (human)
embryonic eye morphogenesis	Retinoic acid receptor gamma	Homo sapiens (human)
retinoic acid receptor signaling pathway	Retinoic acid receptor gamma	Homo sapiens (human)
canonical Wnt signaling pathway	Retinoic acid receptor gamma	Homo sapiens (human)
face development	Retinoic acid receptor gamma	Homo sapiens (human)
trachea cartilage development	Retinoic acid receptor gamma	Homo sapiens (human)
prostate gland epithelium morphogenesis	Retinoic acid receptor gamma	Homo sapiens (human)
Harderian gland development	Retinoic acid receptor gamma	Homo sapiens (human)
cellular response to retinoic acid	Retinoic acid receptor gamma	Homo sapiens (human)
stem cell proliferation	Retinoic acid receptor gamma	Homo sapiens (human)
cellular response to leukemia inhibitory factor	Retinoic acid receptor gamma	Homo sapiens (human)
negative regulation of stem cell proliferation	Retinoic acid receptor gamma	Homo sapiens (human)
cell differentiation	Retinoic acid receptor gamma	Homo sapiens (human)
hormone-mediated signaling pathway	Retinoic acid receptor gamma	Homo sapiens (human)
inositol phosphate metabolic process	Inositol hexakisphosphate kinase 1	Homo sapiens (human)
phosphatidylinositol phosphate biosynthetic process	Inositol hexakisphosphate kinase 1	Homo sapiens (human)
negative regulation of cold-induced thermogenesis	Inositol hexakisphosphate kinase 1	Homo sapiens (human)
inositol phosphate biosynthetic process	Inositol hexakisphosphate kinase 1	Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Process	via Protein(s)	Taxonomy
cytokine activity	Interferon beta	Homo sapiens (human)
cytokine receptor binding	Interferon beta	Homo sapiens (human)
type I interferon receptor binding	Interferon beta	Homo sapiens (human)
protein binding	Interferon beta	Homo sapiens (human)
chloramphenicol O-acetyltransferase activity	Interferon beta	Homo sapiens (human)
TAP binding	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
signaling receptor binding	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
protein binding	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
peptide antigen binding	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
TAP binding	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
protein-folding chaperone binding	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
mRNA regulatory element binding translation repressor activity	Retinoic acid receptor alpha	Homo sapiens (human)
RNA polymerase II transcription regulatory region sequence-specific DNA binding	Retinoic acid receptor alpha	Homo sapiens (human)
RNA polymerase II cis-regulatory region sequence-specific DNA binding	Retinoic acid receptor alpha	Homo sapiens (human)
DNA-binding transcription factor activity, RNA polymerase II-specific	Retinoic acid receptor alpha	Homo sapiens (human)
DNA-binding transcription repressor activity	Retinoic acid receptor alpha	Homo sapiens (human)
transcription coactivator binding	Retinoic acid receptor alpha	Homo sapiens (human)
retinoic acid binding	Retinoic acid receptor alpha	Homo sapiens (human)
chromatin binding	Retinoic acid receptor alpha	Homo sapiens (human)
DNA-binding transcription factor activity	Retinoic acid receptor alpha	Homo sapiens (human)
nuclear receptor activity	Retinoic acid receptor alpha	Homo sapiens (human)
signaling receptor binding	Retinoic acid receptor alpha	Homo sapiens (human)
protein binding	Retinoic acid receptor alpha	Homo sapiens (human)
zinc ion binding	Retinoic acid receptor alpha	Homo sapiens (human)
enzyme binding	Retinoic acid receptor alpha	Homo sapiens (human)
protein domain specific binding	Retinoic acid receptor alpha	Homo sapiens (human)
chromatin DNA binding	Retinoic acid receptor alpha	Homo sapiens (human)
histone deacetylase binding	Retinoic acid receptor alpha	Homo sapiens (human)
protein kinase B binding	Retinoic acid receptor alpha	Homo sapiens (human)
retinoic acid-responsive element binding	Retinoic acid receptor alpha	Homo sapiens (human)
mRNA 5'-UTR binding	Retinoic acid receptor alpha	Homo sapiens (human)
protein kinase A binding	Retinoic acid receptor alpha	Homo sapiens (human)
alpha-actinin binding	Retinoic acid receptor alpha	Homo sapiens (human)
heterocyclic compound binding	Retinoic acid receptor alpha	Homo sapiens (human)
sequence-specific double-stranded DNA binding	Retinoic acid receptor alpha	Homo sapiens (human)
DNA-binding transcription factor activity, RNA polymerase II-specific	Retinoic acid receptor gamma	Homo sapiens (human)
DNA binding	Retinoic acid receptor gamma	Homo sapiens (human)
chromatin binding	Retinoic acid receptor gamma	Homo sapiens (human)
DNA-binding transcription factor activity	Retinoic acid receptor gamma	Homo sapiens (human)
protein binding	Retinoic acid receptor gamma	Homo sapiens (human)
zinc ion binding	Retinoic acid receptor gamma	Homo sapiens (human)
nuclear retinoid X receptor binding	Retinoic acid receptor gamma	Homo sapiens (human)
sequence-specific double-stranded DNA binding	Retinoic acid receptor gamma	Homo sapiens (human)
nuclear receptor activity	Retinoic acid receptor gamma	Homo sapiens (human)
RNA polymerase II cis-regulatory region sequence-specific DNA binding	Retinoic acid receptor gamma	Homo sapiens (human)
inositol-1,3,4,5,6-pentakisphosphate kinase activity	Inositol hexakisphosphate kinase 1	Homo sapiens (human)
inositol hexakisphosphate kinase activity	Inositol hexakisphosphate kinase 1	Homo sapiens (human)
inositol heptakisphosphate kinase activity	Inositol hexakisphosphate kinase 1	Homo sapiens (human)
inositol hexakisphosphate 5-kinase activity	Inositol hexakisphosphate kinase 1	Homo sapiens (human)
protein binding	Inositol hexakisphosphate kinase 1	Homo sapiens (human)
ATP binding	Inositol hexakisphosphate kinase 1	Homo sapiens (human)
inositol hexakisphosphate 1-kinase activity	Inositol hexakisphosphate kinase 1	Homo sapiens (human)
inositol hexakisphosphate 3-kinase activity	Inositol hexakisphosphate kinase 1	Homo sapiens (human)
inositol 5-diphosphate pentakisphosphate 5-kinase activity	Inositol hexakisphosphate kinase 1	Homo sapiens (human)
inositol diphosphate tetrakisphosphate kinase activity	Inositol hexakisphosphate kinase 1	Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Process	via Protein(s)	Taxonomy
extracellular space	Interferon beta	Homo sapiens (human)
extracellular region	Interferon beta	Homo sapiens (human)
Golgi membrane	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
endoplasmic reticulum	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
Golgi apparatus	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
plasma membrane	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
cell surface	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
ER to Golgi transport vesicle membrane	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
membrane	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
secretory granule membrane	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
phagocytic vesicle membrane	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
early endosome membrane	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
recycling endosome membrane	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
extracellular exosome	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
lumenal side of endoplasmic reticulum membrane	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
MHC class I protein complex	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
extracellular space	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
external side of plasma membrane	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
nucleus	Retinoic acid receptor alpha	Homo sapiens (human)
nucleoplasm	Retinoic acid receptor alpha	Homo sapiens (human)
transcription regulator complex	Retinoic acid receptor alpha	Homo sapiens (human)
nucleolus	Retinoic acid receptor alpha	Homo sapiens (human)
cytoplasm	Retinoic acid receptor alpha	Homo sapiens (human)
cytosol	Retinoic acid receptor alpha	Homo sapiens (human)
plasma membrane	Retinoic acid receptor alpha	Homo sapiens (human)
actin cytoskeleton	Retinoic acid receptor alpha	Homo sapiens (human)
dendrite	Retinoic acid receptor alpha	Homo sapiens (human)
perinuclear region of cytoplasm	Retinoic acid receptor alpha	Homo sapiens (human)
RNA polymerase II transcription regulator complex	Retinoic acid receptor alpha	Homo sapiens (human)
chromatin	Retinoic acid receptor alpha	Homo sapiens (human)
protein-containing complex	Retinoic acid receptor alpha	Homo sapiens (human)
nucleus	Retinoic acid receptor alpha	Homo sapiens (human)
nucleus	Retinoic acid receptor gamma	Homo sapiens (human)
nucleoplasm	Retinoic acid receptor gamma	Homo sapiens (human)
cytoplasm	Retinoic acid receptor gamma	Homo sapiens (human)
membrane	Retinoic acid receptor gamma	Homo sapiens (human)
chromatin	Retinoic acid receptor gamma	Homo sapiens (human)
transcription regulator complex	Retinoic acid receptor gamma	Homo sapiens (human)
nucleus	Retinoic acid receptor gamma	Homo sapiens (human)
fibrillar center	Inositol hexakisphosphate kinase 1	Homo sapiens (human)
nucleoplasm	Inositol hexakisphosphate kinase 1	Homo sapiens (human)
cytosol	Inositol hexakisphosphate kinase 1	Homo sapiens (human)
nucleus	Inositol hexakisphosphate kinase 1	Homo sapiens (human)
cytoplasm	Inositol hexakisphosphate kinase 1	Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Assay ID	Title	Year	Journal	Article
AID748293	Inhibition of spermatogenesis in CD1 mouse assessed as asynchronization of spermatogenic cell association at 10 mg/kg, po for 7 days measured after 1 month by bright-field microscopic analysis	2013	ACS medicinal chemistry letters, May-09, Volume: 4, Issue:5	Pharmacological activity of retinoic acid receptor alpha-selective antagonists
AID748296	Inhibition of spermatogenesis in CD1 mouse assessed as change in sperm release at stage 9 into lumen in testes at 2 to 10 mg/kg, po for 7 days measured after 1 month by bright-field microscopic analysis relative to control	2013	ACS medicinal chemistry letters, May-09, Volume: 4, Issue:5	Pharmacological activity of retinoic acid receptor alpha-selective antagonists
AID748289	Toxicity in CD1 mouse assessed as change in testosterone levels at 2 to 10 mg/kg, po for 7 days by enzyme immunoassay relative to control	2013	ACS medicinal chemistry letters, May-09, Volume: 4, Issue:5	Pharmacological activity of retinoic acid receptor alpha-selective antagonists
AID748292	Inhibition of spermatogenesis in CD1 mouse assessed as change in morphology of caudal epididymides at 10 mg/kg, po for 7 days measured after 1 month by bright-field microscopic analysis	2013	ACS medicinal chemistry letters, May-09, Volume: 4, Issue:5	Pharmacological activity of retinoic acid receptor alpha-selective antagonists
AID748291	Inhibition of spermatogenesis in CD1 mouse assessed as change in motility of epididymal sperm at 10 mg/kg, po for 7 days measured after 1 month by bright-field microscopic analysis	2013	ACS medicinal chemistry letters, May-09, Volume: 4, Issue:5	Pharmacological activity of retinoic acid receptor alpha-selective antagonists
AID748298	Antagonist activity at human RARalpha expressed in human HeLa cells assessed as inhibition of ATRA-induced RARE-chloramphenicol acetyltransferase reporter gene expression after 24 hrs by transactivation competition assay	2013	ACS medicinal chemistry letters, May-09, Volume: 4, Issue:5	Pharmacological activity of retinoic acid receptor alpha-selective antagonists
AID748299	Antagonist activity at human RARalpha expressed in human HeLa cells assessed as inhibition of ATRA-induced RARE transactivation after 24 hrs by chloramphenicol acetyltransferase reporter gene assay	2013	ACS medicinal chemistry letters, May-09, Volume: 4, Issue:5	Pharmacological activity of retinoic acid receptor alpha-selective antagonists
AID748294	Inhibition of spermatogenesis in CD1 mouse assessed as presence of vacuolar-like spaces at 10 mg/kg, po for 7 days measured after 1 month by bright-field microscopic analysis	2013	ACS medicinal chemistry letters, May-09, Volume: 4, Issue:5	Pharmacological activity of retinoic acid receptor alpha-selective antagonists
AID748297	Inhibition of spermatogenesis in CD1 mouse assessed as change in alignment of step 16 spermatids at lumen in stage 8 tubules in testes at 2 to 10 mg/kg, po for 7 days measured after 1 month by bright-field microscopic analysis relative to control	2013	ACS medicinal chemistry letters, May-09, Volume: 4, Issue:5	Pharmacological activity of retinoic acid receptor alpha-selective antagonists
AID748295	Toxicity in CD1 mouse assessed as change in testicular weight at 2 to 10 mg/kg, po for 7 days relative to control	2013	ACS medicinal chemistry letters, May-09, Volume: 4, Issue:5	Pharmacological activity of retinoic acid receptor alpha-selective antagonists
AID748290	Toxicity in CD1 mouse assessed as change in body weight at 2 to 10 mg/kg, po	2013	ACS medicinal chemistry letters, May-09, Volume: 4, Issue:5	Pharmacological activity of retinoic acid receptor alpha-selective antagonists
AID1347161	Confirmatory screen NINDS Rhodamine qHTS for Zika virus inhibitors	2020	Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49	Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
AID1346986	P-glycoprotein substrates identified in KB-3-1 adenocarcinoma cell line, qHTS therapeutic library screen	2019	Molecular pharmacology, 11, Volume: 96, Issue:5	A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
AID1347164	384 well plate NINDS Rhodamine confirmatory qHTS for Zika virus inhibitors	2020	Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49	Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
AID1347160	Primary screen NINDS Rhodamine qHTS for Zika virus inhibitors	2020	Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49	Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
AID1347158	ZIKV-mCherry secondary qHTS for Zika virus inhibitors	2020	Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49	Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
AID1347163	384 well plate NINDS AMC confirmatory qHTS for Zika virus inhibitors	2020	Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49	Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
AID1296008	Cytotoxic Profiling of Annotated Libraries Using Quantitative High-Throughput Screening	2020	SLAS discovery : advancing life sciences R & D, 01, Volume: 25, Issue:1	Cytotoxic Profiling of Annotated and Diverse Chemical Libraries Using Quantitative High-Throughput Screening.
AID1347167	Vero cells viability qHTS for Zika virus inhibitors	2020	Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49	Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
AID1346987	P-glycoprotein substrates identified in KB-8-5-11 adenocarcinoma cell line, qHTS therapeutic library screen	2019	Molecular pharmacology, 11, Volume: 96, Issue:5	A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
AID1347168	HepG2 cells viability qHTS for Zika virus inhibitors	2020	Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49	Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
AID1347153	Confirmatory screen GU AMC qHTS for Zika virus inhibitors	2020	Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49	Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
AID1347156	DAPI mCherry counterscreen qHTS for Zika virus inhibitors	2020	Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49	Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
AID1347169	Tertiary RLuc qRT-PCR qHTS assay for Zika virus inhibitors	2020	Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49	Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
AID1347157	Confirmatory screen GU Rhodamine qHTS for Zika virus inhibitors qHTS	2020	Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49	Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
AID1347159	Primary screen GU Rhodamine qHTS for Zika virus inhibitors: Unlinked NS2B-NS3 protease assay	2020	Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49	Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
AID1347152	Confirmatory screen NINDS AMC qHTS for Zika virus inhibitors	2020	Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49	Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
AID1347149	Furin counterscreen qHTS for Zika virus inhibitors	2020	Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49	Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
AID1799455	Competitive Assay from Article 10.1016/S1074-5521(99)80084-2: \\Structural basis for engineering of retinoic acid receptor isotype-selective agonists and antagonists.\\	1999	Chemistry & biology, Aug, Volume: 6, Issue:8	Structural basis for engineering of retinoic acid receptor isotype-selective agonists and antagonists.
AID1794808	Fluorescence-based screening to identify small molecule inhibitors of Plasmodium falciparum apicoplast DNA polymerase (Pf-apPOL).	2014	Journal of biomolecular screening, Jul, Volume: 19, Issue:6	A High-Throughput Assay to Identify Inhibitors of the Apicoplast DNA Polymerase from Plasmodium falciparum.
AID1794808	Fluorescence-based screening to identify small molecule inhibitors of Plasmodium falciparum apicoplast DNA polymerase (Pf-apPOL).
AID1346740	Human Retinoic acid receptor-alpha (1B. Retinoic acid receptors)	1999	Chemistry & biology, Aug, Volume: 6, Issue:8	Structural basis for engineering of retinoic acid receptor isotype-selective agonists and antagonists.
AID1346740	Human Retinoic acid receptor-alpha (1B. Retinoic acid receptors)	2000	Molecular cell, Feb, Volume: 5, Issue:2	Crystal structure of a heterodimeric complex of RAR and RXR ligand-binding domains.
AID1346740	Human Retinoic acid receptor-alpha (1B. Retinoic acid receptors)	2002	Nature, Jan-10, Volume: 415, Issue:6868	Co-regulator recruitment and the mechanism of retinoic acid receptor synergy.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	0 (0.00)	18.7374
1990's	1 (11.11)	18.2507
2000's	2 (22.22)	29.6817
2010's	3 (33.33)	24.3611
2020's	3 (33.33)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	9 (100.00%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Description	Relationhip Strength	Studies	Classes	Roles
bms 961	[no description available]	medium	1
bms 204493	[no description available]	medium	1	acetylenic compound; benzoic acids; dihydronaphthalenes; stilbenoid	retinoic acid receptor antagonist
bms453	[no description available]	high	1	benzoic acids; dihydronaphthalenes; stilbenoid	retinoic acid receptor alpha antagonist; retinoic acid receptor beta agonist; retinoic acid receptor gamma antagonist; teratogenic agent
o-(chloroacetylcarbamoyl)fumagillol	[no description available]	low	0	carbamate ester; organochlorine compound; semisynthetic derivative; sesquiterpenoid; spiro-epoxide	angiogenesis inhibitor; antineoplastic agent; EC 1.5.1.3 (dihydrofolate reductase) inhibitor; methionine aminopeptidase 2 inhibitor; retinoic acid receptor alpha antagonist
ro 41-5253	[no description available]	medium	0	aromatic ether; benzoic acids; sulfone; thiochromane	apoptosis inducer; retinoic acid receptor alpha antagonist
5,7-dichlorokynurenic acid	[no description available]	low	0	quinolines
broxyquinoline	[no description available]	low	0	organohalogen compound; quinolines
bu 224	[no description available]	low	0	quinolines
cilostamide	[no description available]	low	0	quinolines
cloxyquin	[no description available]	low	0	organochlorine compound; quinolines
ethoxyquin	[no description available]	low	0	aromatic ether; quinolines	antifungal agrochemical; food antioxidant; genotoxin; geroprotector; herbicide; Hsp90 inhibitor; neuroprotective agent; UDP-glucuronosyltransferase activator
fleroxacin	[no description available]	low	0	difluorobenzene; fluoroquinolone antibiotic; monocarboxylic acid; N-alkylpiperazine; quinolines	antibacterial drug; EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor; topoisomerase IV inhibitor
mefloquine hydrochloride	[no description available]	low	0	organofluorine compound; piperidines; quinolines; secondary alcohol
oxamniquine	[no description available]	low	0	aromatic primary alcohol; C-nitro compound; quinolines; secondary amino compound
procaterol	[no description available]	low	0	quinolines
6-nitroquipazine	[no description available]	low	0	nitro compound; quinolines
pf 5901	[no description available]	low	0	quinolines
quinophthalone	[no description available]	low	0	aromatic ketone; beta-diketone; quinolines	dye
echinopsine	[no description available]	low	0	quinolines
dimoxyline	[no description available]	low	0	quinolines
quinoline	[no description available]	low	0	azaarene; mancude organic heterobicyclic parent; ortho-fused heteroarene; quinolines
6-methylquinoline	[no description available]	low	0	quinolines
2-methylquinoline	[no description available]	low	0	quinolines
cinchophen	[no description available]	low	0	quinolines
oxycinchophen	[no description available]	low	0	quinolines
6-methoxyquinoline	[no description available]	low	0	aromatic ether; quinolines
actinoquinol	[no description available]	low	0	quinolines
nequinate	[no description available]	low	0	quinolines
miloxacin	[no description available]	low	0	quinolines
amifloxacin	[no description available]	low	0	quinolines
sarafloxacin	[no description available]	low	0	quinolines
rufloxacin	[no description available]	low	0	fluoroquinolone antibiotic; quinolines; quinolone antibiotic
clinafloxacin	[no description available]	low	0	quinolines
orbifloxacin	[no description available]	low	0	quinolines
marbofloxacin	[no description available]	low	0	quinolines
toborinone	[no description available]	low	0	quinolines
3,4-dihydro-2(1h)-quinolinone	[no description available]	low	0	quinolines
tilbroquinol	[no description available]	low	0	organohalogen compound; quinolines
pazufloxacin	[no description available]	low	0	quinolines
7-(trifluoromethyl)-1H-quinolin-4-one	[no description available]	low	0	quinolines
2-Methyl-4-quinolinol	[no description available]	low	0	quinolines
1,2,3,4-tetrahydroquinoline	[no description available]	low	0	quinolines
danofloxacin	[no description available]	low	0	quinolines
premafloxacin	[no description available]	low	0	quinolines
quinfamide	[no description available]	low	0	quinolines
grepafloxacin	[no description available]	low	0	fluoroquinolone antibiotic; quinolines; quinolone antibiotic
8-hydroxy-2-quinolinecarboxylic acid	[no description available]	low	0	quinolines
8-(trifluoromethyl)-1H-quinolin-4-one	[no description available]	low	0	quinolines
cloquintocet-mexyl	[no description available]	low	0	aromatic ether; carboxylic ester; organochlorine compound; quinolines
2-hydroxyamino-3-methylimidazolo(4,5-f)quinoline	[no description available]	low	0	quinolines
ulifloxacin	[no description available]	low	0	quinolines
8-hydroxycarteolol	[no description available]	low	0	quinolines
3-(4-carboxybenzoyl)-2-quinolinecarboxaldehyde	[no description available]	low	0	benzoic acids; quinolines	fluorochrome
sr 2640	[no description available]	low	0	quinolines
a 195773	[no description available]	low	0	macrolide antibiotic; monosaccharide derivative; quinolines	antibacterial drug; protein synthesis inhibitor
torcetrapib	[no description available]	low	0	(trifluoromethyl)benzenes; carbamate ester; quinolines	anticholesteremic drug; CETP inhibitor
mefloquine carboxylic acid	[no description available]	low	0	quinolines
6-Methoxyquinoline N-oxide	[no description available]	low	0	quinolines
1-[(4-methoxyphenyl)-oxomethyl]-2H-quinoline-2-carbonitrile	[no description available]	low	0	quinolines
2-quinolinecarboxylic acid (4-nitrophenyl) ester	[no description available]	low	0	quinolines
3-nitro-1H-quinolin-4-one	[no description available]	low	0	nitro compound; quinolines
graveoline	[no description available]	low	0	quinolines
Dubamine	[no description available]	low	0	quinolines
saquinavir	[no description available]	low	0	L-asparagine derivative; quinolines	antiviral drug; HIV protease inhibitor
hts 466284	[no description available]	low	0	pyrazoles; pyridines; quinolines	TGFbeta receptor antagonist
5-carboxy-8-hydroxyquinoline	[no description available]	low	0	quinolines
sitafloxacin	[no description available]	low	0	fluoroquinolone antibiotic; quinolines; quinolone antibiotic
8-prop-2-enylsulfonylquinoline	[no description available]	low	0	quinolines
2-amino-3-cyano-5,6,7,8-tetrahydroquinoline-4-carboxylic acid methyl ester	[no description available]	low	0	quinolines
3-[[cyclopentyl-[[1-(phenylmethyl)-5-tetrazolyl]methyl]amino]methyl]-8-methyl-1H-quinolin-2-one	[no description available]	low	0	quinolines
N-[(8-methyl-2-oxo-1H-quinolin-3-yl)methyl]-N-(2-oxolanylmethyl)-2-furancarboxamide	[no description available]	low	0	quinolines
3-[(1-cyclopentyl-5-tetrazolyl)-(3,4-dihydro-1H-isoquinolin-2-yl)methyl]-7-methoxy-1H-quinolin-2-one	[no description available]	low	0	quinolines
3-[[1,3-benzodioxol-5-ylmethyl-[[1-(2-furanylmethyl)-5-tetrazolyl]methyl]amino]methyl]-6-methyl-1H-quinolin-2-one	[no description available]	low	0	quinolines
1-[3-(dimethylamino)propyl]-3-(4-fluorophenyl)-1-[(6-methoxy-2-oxo-1H-quinolin-3-yl)methyl]urea	[no description available]	low	0	quinolines
1-[3-(dimethylamino)propyl]-1-[(6-methoxy-2-oxo-1H-quinolin-3-yl)methyl]-3-phenylurea	[no description available]	low	0	quinolines
6-[[4-(1,3-benzodioxol-5-ylmethyl)-1-piperazinyl]-[1-(2-methylbutan-2-yl)-5-tetrazolyl]methyl]quinoline	[no description available]	low	0	quinolines
3-[(1-tert-butyl-5-tetrazolyl)-[2-furanylmethyl(2-oxolanylmethyl)amino]methyl]-6-methoxy-1H-quinolin-2-one	[no description available]	low	0	quinolines
3-[[1,3-benzodioxol-5-ylmethyl-[(1-cyclopentyl-5-tetrazolyl)methyl]amino]methyl]-6-ethyl-1H-quinolin-2-one	[no description available]	low	0	quinolines
6-ethyl-3-[[[1-(2-furanylmethyl)-5-tetrazolyl]methyl-(phenylmethyl)amino]methyl]-1H-quinolin-2-one	[no description available]	low	0	quinolines
N-(2-hydroxyethyl)-5-methyl-N-[(7-oxo-3,6-dihydro-2H-[1,4]dioxino[2,3-g]quinolin-8-yl)methyl]-2,1,3-benzothiadiazole-4-sulfonamide	[no description available]	low	0	quinolines
3-[[[1-[1-(2-furanylmethyl)-5-tetrazolyl]-2-methylpropyl]-(2-oxolanylmethyl)amino]methyl]-8-methyl-1H-quinolin-2-one	[no description available]	low	0	quinolines
6,8-dimethyl-3-[(3-methyl-1-piperidinyl)-[1-(2-oxolanylmethyl)-5-tetrazolyl]methyl]-1H-quinolin-2-one	[no description available]	low	0	quinolines
1-[3-(4-morpholinyl)propyl]-1-[(7-oxo-3,6-dihydro-2H-[1,4]dioxino[2,3-g]quinolin-8-yl)methyl]-3-phenylurea	[no description available]	low	0	quinolines
6-methyl-3-[[[1-(phenylmethyl)-5-tetrazolyl]methyl-(thiophen-2-ylmethyl)amino]methyl]-1H-quinolin-2-one	[no description available]	low	0	quinolines
N-[(6-ethoxy-2-oxo-1H-quinolin-3-yl)methyl]-4-fluoro-N-(2-hydroxyethyl)benzamide	[no description available]	low	0	quinolines
6-ethoxy-3-[[2-oxolanylmethyl-[[1-(2-phenylethyl)-5-tetrazolyl]methyl]amino]methyl]-1H-quinolin-2-one	[no description available]	low	0	quinolines
1-[(7,8-dimethyl-2-oxo-1H-quinolin-3-yl)methyl]-1-[(1-ethyl-2-pyrrolidinyl)methyl]-3-(2-methoxyphenyl)urea	[no description available]	low	0	quinolines
3-[1-azepanyl-[1-(phenylmethyl)-5-tetrazolyl]methyl]-7-methoxy-1H-quinolin-2-one	[no description available]	low	0	quinolines
3-[[[1-(2-furanylmethyl)-5-tetrazolyl]methyl-[(2-methoxyphenyl)methyl]amino]methyl]-6-methyl-1H-quinolin-2-one	[no description available]	low	0	quinolines
7-[[1-(2-oxolanylmethyl)-5-tetrazolyl]-(1-pyrrolidinyl)methyl]-5H-[1,3]dioxolo[4,5-g]quinolin-6-one	[no description available]	low	0	quinolines
1-(1,3-benzodioxol-5-ylmethyl)-3-(4-methylphenyl)-1-[(7-oxo-3,6-dihydro-2H-[1,4]dioxino[2,3-g]quinolin-8-yl)methyl]urea	[no description available]	low	0	quinolines
N-[(7-methoxy-2-oxo-1H-quinolin-3-yl)methyl]-N-(3-pyridinylmethyl)benzenesulfonamide	[no description available]	low	0	quinolines
1-[(1-tert-butyl-5-tetrazolyl)-thiophen-2-ylmethyl]-3,4-dihydro-2H-quinoline	[no description available]	low	0	quinolines
2-[(3-ethyl-2-quinolinyl)thio]-N-(5-methyl-3-isoxazolyl)acetamide	[no description available]	low	0	quinolines
3-cyclohexyl-1-[(7-oxo-3,6-dihydro-2H-[1,4]dioxino[2,3-g]quinolin-8-yl)methyl]-1-[2-(1-pyrrolidinyl)ethyl]urea	[no description available]	low	0	quinolines
1-[(6-methoxy-2-oxo-1H-quinolin-3-yl)methyl]-3-(4-methoxyphenyl)-1-(2-oxolanylmethyl)urea	[no description available]	low	0	quinolines
3-[3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazin-2-yl-[1-(2-oxolanylmethyl)-5-tetrazolyl]methyl]-6-ethyl-1H-quinolin-2-one	[no description available]	low	0	quinolines
N-[(6-methoxy-2-oxo-1H-quinolin-3-yl)methyl]-N-(2-methylphenyl)propanamide	[no description available]	low	0	quinolines
3-[[[1-[(4-fluorophenyl)methyl]-5-tetrazolyl]methyl-(2-hydroxyethyl)amino]methyl]-7-methyl-1H-quinolin-2-one	[no description available]	low	0	quinolines
1-[2-(dimethylamino)ethyl]-1-[(6-methoxy-2-oxo-1H-quinolin-3-yl)methyl]-3-(phenylmethyl)urea	[no description available]	low	0	quinolines
2-[[2-(1-azepanyl)-2-oxoethyl]thio]-6-methoxy-3-quinolinecarbonitrile	[no description available]	low	0	quinolines
6-methoxy-3-[[2-oxolanylmethyl-[1-[1-(phenylmethyl)-5-tetrazolyl]propyl]amino]methyl]-1H-quinolin-2-one	[no description available]	low	0	quinolines
3-[2-hydroxyethyl-[(6-methoxy-2-oxo-1H-quinolin-3-yl)methyl]sulfamoyl]benzoic acid ethyl ester	[no description available]	low	0	quinolines
3-(3-chlorophenyl)-1-(3-hydroxypropyl)-1-[(8-methyl-2-oxo-1H-quinolin-3-yl)methyl]urea	[no description available]	low	0	quinolines
6-methoxy-3-[[[1-(2-methoxyethyl)-5-tetrazolyl]methyl-(3-pyridinylmethyl)amino]methyl]-1H-quinolin-2-one	[no description available]	low	0	quinolines
4-bromo-N-[(6-ethoxy-2-oxo-1H-quinolin-3-yl)methyl]-N-(2-hydroxyethyl)benzamide	[no description available]	low	0	quinolines
6-ethoxy-3-[[[1-(2-methylbutan-2-yl)-5-tetrazolyl]methyl-(thiophen-2-ylmethyl)amino]methyl]-1H-quinolin-2-one	[no description available]	low	0	quinolines
3-[3,4-dihydro-1H-isoquinolin-2-yl-[1-(2-methylbutan-2-yl)-5-tetrazolyl]methyl]-7-methoxy-1H-quinolin-2-one	[no description available]	low	0	quinolines
1-[3-(dimethylamino)propyl]-1-[(5,8-dimethyl-2-oxo-1H-quinolin-3-yl)methyl]-3-(phenylmethyl)urea	[no description available]	low	0	quinolines
3-(2-chlorophenyl)-1-[(6-methoxy-2-oxo-1H-quinolin-3-yl)methyl]-1-[2-(1-pyrrolidinyl)ethyl]urea	[no description available]	low	0	quinolines
8-[(1-tert-butyl-5-tetrazolyl)-thiomorpholin-4-ylmethyl]-3,6-dihydro-2H-[1,4]dioxino[2,3-g]quinolin-7-one	[no description available]	low	0	quinolines
1-cyclopentyl-1-[(7-methoxy-2-oxo-1H-quinolin-3-yl)methyl]-3-(2-methoxyphenyl)urea	[no description available]	low	0	quinolines
3-[3,4-dihydro-1H-isoquinolin-2-yl-[1-(2-oxolanylmethyl)-5-tetrazolyl]methyl]-6-methyl-1H-quinolin-2-one	[no description available]	low	0	quinolines
2-fluoro-N-(2-hydroxyethyl)-N-[(6-methoxy-2-oxo-1H-quinolin-3-yl)methyl]benzamide	[no description available]	low	0	quinolines
3-[[(1-tert-butyl-5-tetrazolyl)methyl-(thiophen-2-ylmethyl)amino]methyl]-6-ethoxy-1H-quinolin-2-one	[no description available]	low	0	quinolines
6-ethoxy-3-[[2-furanylmethyl-[[1-(phenylmethyl)-5-tetrazolyl]methyl]amino]methyl]-1H-quinolin-2-one	[no description available]	low	0	quinolines
3-[1-azepanyl-[1-[(4-fluorophenyl)methyl]-5-tetrazolyl]methyl]-6,7-dimethoxy-1H-quinolin-2-one	[no description available]	low	0	quinolines
N-(2-furanylmethyl)-N-[(6-methoxy-2-oxo-1H-quinolin-3-yl)methyl]benzamide	[no description available]	low	0	quinolines
N-[(6,7-dimethoxy-2-oxo-1H-quinolin-3-yl)methyl]-N-(3-hydroxypropyl)benzenesulfonamide	[no description available]	low	0	quinolines
6-methoxy-3-[[2-oxolanylmethyl-[[1-(phenylmethyl)-5-tetrazolyl]methyl]amino]methyl]-1H-quinolin-2-one	[no description available]	low	0	quinolines
1-[(6,7-dimethoxy-2-oxo-1H-quinolin-3-yl)methyl]-3-(phenylmethyl)-1-(3-pyridinylmethyl)urea	[no description available]	low	0	quinolines
4-[2-(3,4-dihydro-2H-quinolin-1-yl)-2-oxoethyl]-5-furo[3,2-b]pyrrolecarboxylic acid ethyl ester	[no description available]	low	0	quinolines
4-methyl-6-(methylthio)-1H-quinolin-2-one	[no description available]	low	0	quinolines
2-[(3-cyano-5,7-dimethyl-2-quinolinyl)thio]-N-(2-furanylmethyl)acetamide	[no description available]	low	0	quinolines
3-[[cyclopentyl-[[1-[(4-methoxyphenyl)methyl]-5-tetrazolyl]methyl]amino]methyl]-7-methyl-1H-quinolin-2-one	[no description available]	low	0	quinolines
3-cyclohexyl-1-[(6,7-dimethyl-2-oxo-1H-quinolin-3-yl)methyl]-1-[3-(4-morpholinyl)propyl]urea	[no description available]	low	0	quinolines
3-[[1-(1,3-benzodioxol-5-ylmethyl)-5-tetrazolyl]-(1-pyrrolidinyl)methyl]-8-methyl-1H-quinolin-2-one	[no description available]	low	0	quinolines
3-[[1-[1-(2-furanylmethyl)-5-tetrazolyl]propyl-(2-phenylethyl)amino]methyl]-7-methoxy-1H-quinolin-2-one	[no description available]	low	0	quinolines
1-[(5,8-dimethyl-2-oxo-1H-quinolin-3-yl)methyl]-1-(2-furanylmethyl)-3-phenylurea	[no description available]	low	0	quinolines
N-(2-furanylmethyl)-N-[(7-methyl-4-tetrazolo[1,5-a]quinolinyl)methyl]-2-phenoxyacetamide	[no description available]	low	0	quinolines
9-oxo-N-(3-pyridinylmethyl)-3,6-dihydro-2H-[1,4]dioxino[2,3-g]quinoline-8-carboxamide	[no description available]	low	0	aromatic amide; quinolines
(6-fluoro-2-methyl-3,4-dihydro-2H-quinolin-1-yl)-[5-(2-furanyl)-7-(trifluoromethyl)-2-pyrazolo[1,5-a]pyrimidinyl]methanone	[no description available]	low	0	quinolines
6-methoxy-3-[[[1-(2-oxolanylmethyl)-5-tetrazolyl]methyl-(2-phenylethyl)amino]methyl]-1H-quinolin-2-one	[no description available]	low	0	quinolines
N-[(6-methoxy-2-oxo-1H-quinolin-3-yl)methyl]-N-(thiophen-2-ylmethyl)-2,1,3-benzothiadiazole-4-sulfonamide	[no description available]	low	0	quinolines
1-piperidinecarboxylic acid (5-chloro-8-quinolinyl) ester	[no description available]	low	0	organochlorine compound; quinolines
N-[(5,8-dimethyl-2-oxo-1H-quinolin-3-yl)methyl]-4-methoxy-N-[3-(2-oxo-1-pyrrolidinyl)propyl]benzenesulfonamide	[no description available]	low	0	quinolines
4-chloro-N-[(7-oxo-3,6-dihydro-2H-[1,4]dioxino[2,3-g]quinolin-8-yl)methyl]-N-(2-oxolanylmethyl)benzenesulfonamide	[no description available]	low	0	quinolines
3-[3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazin-2-yl-[1-(2-oxolanylmethyl)-5-tetrazolyl]methyl]-5,7-dimethyl-1H-quinolin-2-one	[no description available]	low	0	quinolines
2-[[3-cyano-4-(5-methyl-2-furanyl)-5,6,7,8-tetrahydroquinolin-2-yl]thio]acetic acid methyl ester	[no description available]	low	0	quinolines
N-[(2R,4S)-2-methyl-1-(1-oxopropyl)-3,4-dihydro-2H-quinolin-4-yl]-N-phenylacetamide	[no description available]	low	0	quinolines
1-ethyl-6-methoxy-4-oxo-3-quinolinecarboxylic acid	[no description available]	low	0	quinolines
2-[[3-cyano-4-(2-furanyl)-5,6,7,8-tetrahydroquinolin-2-yl]thio]-N-(2-methylphenyl)acetamide	[no description available]	low	0	quinolines
2-(6-bromo-2-methyl-4-oxo-1-quinolinyl)-N-(2-methoxyphenyl)acetamide	[no description available]	low	0	quinolines
3-methyl-N-(1-propyl-3-pyrazolo[3,4-b]quinolinyl)butanamide	[no description available]	low	0	quinolines
N-(1-propyl-3-pyrazolo[3,4-b]quinolinyl)butanamide	[no description available]	low	0	quinolines
3-[(4-methoxyanilino)methyl]-1H-quinolin-2-one	[no description available]	low	0	quinolines
N-[(6-methoxy-2-oxo-1H-quinolin-3-yl)methyl]-N-methyl-4-pyridinecarboxamide	[no description available]	low	0	quinolines
3-(ethylaminomethyl)-6-methyl-1H-quinolin-2-one	[no description available]	low	0	quinolines
N-(1,8-dimethyl-3-pyrazolo[3,4-b]quinolinyl)propanamide	[no description available]	low	0	quinolines
2-methoxy-N-[(6-methoxy-2-oxo-1H-quinolin-3-yl)methyl]-N-(2-methoxyphenyl)acetamide	[no description available]	low	0	quinolines
2,3-dihydroindol-1-yl-(6-fluoro-2-methyl-4-quinolinyl)methanone	[no description available]	low	0	quinolines
N-(1-ethyl-7-methyl-3-pyrazolo[3,4-b]quinolinyl)-2-furancarboxamide	[no description available]	low	0	quinolines
N-[(6-methoxy-2-oxo-1H-quinolin-3-yl)methyl]-N-(4-methylphenyl)-2-oxolanecarboxamide	[no description available]	low	0	quinolines
N-[(7-methyl-2-oxo-1H-quinolin-3-yl)methyl]-N-propan-2-yl-4-pyridinecarboxamide	[no description available]	low	0	quinolines
N-[(7-methyl-2-oxo-1H-quinolin-3-yl)methyl]-N-propyl-2-pyridinecarboxamide	[no description available]	low	0	quinolines
N-butyl-N-[(6-methoxy-2-oxo-1H-quinolin-3-yl)methyl]-2-pyridinecarboxamide	[no description available]	low	0	quinolines
N-(1,7-dimethyl-3-pyrazolo[3,4-b]quinolinyl)acetamide	[no description available]	low	0	quinolines
N-(1-ethyl-6-methyl-3-pyrazolo[3,4-b]quinolinyl)-4-pyridinecarboxamide	[no description available]	low	0	quinolines
N-(2-furanylmethyl)-N-[(8-methyl-2-oxo-1H-quinolin-3-yl)methyl]-2-thiophenecarboxamide	[no description available]	low	0	quinolines
5-(1-imidazolylsulfonyl)-8-methoxyquinoline	[no description available]	low	0	quinolines
2-amino-4-(5-methyl-2-furanyl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile	[no description available]	low	0	quinolines
2-(8-quinolinylthio)acetic acid	[no description available]	low	0	quinolines
4-chloro-1-methyl-3-nitro-2-quinolinone	[no description available]	low	0	nitro compound; quinolines
4-(1H-benzimidazol-2-yl)quinoline	[no description available]	low	0	quinolines
3-[(4,8-dimethyl-2-quinolinyl)thio]propanoic acid	[no description available]	low	0	quinolines
3-pyridinecarboxylic acid (5-chloro-8-quinolinyl) ester	[no description available]	low	0	organochlorine compound; quinolines
2-amino-4-thiophen-2-yl-5,6,7,8-tetrahydroquinoline-3-carbonitrile	[no description available]	low	0	quinolines
2,2,2-trifluoro-N-(2-methyl-8-quinolinyl)acetamide	[no description available]	low	0	quinolines; secondary carboxamide; trifluoroacetamide
8-(3,5-dimethyl-1-pyrazolyl)quinoline	[no description available]	low	0	quinolines
1-methyl-4-[(4-methylphenyl)thio]-3-nitro-2-quinolinone	[no description available]	low	0	nitro compound; quinolines
4-chloro-2-methyl-3-(3-oxobutyl)-6-quinolinecarboxylic acid	[no description available]	low	0	quinolines
4-chloro-1-ethyl-3-nitro-2-quinolinone	[no description available]	low	0	nitro compound; quinolines
4-chloro-3-nitro-1-(phenylmethyl)-2-quinolinone	[no description available]	low	0	quinolines
6-(1,4,5,7-tetramethyl-6-pyrrolo[3,4-d]pyridazinyl)quinoline	[no description available]	low	0	quinolines
N-[[(2,4-dimethyl-8-quinolinyl)amino]-sulfanylidenemethyl]-4-methylbenzamide	[no description available]	low	0	quinolines
4,7-dimethoxy-1-methyl-2-quinolinone	[no description available]	low	0	quinolines
N-[3,4-dihydro-2H-quinolin-1-yl(sulfanylidene)methyl]-2-(3-methylphenoxy)acetamide	[no description available]	low	0	quinolines
2-[(7-ethyl-[1,3]dioxolo[4,5-g]quinolin-6-yl)thio]acetic acid propan-2-yl ester	[no description available]	low	0	quinolines
N-cyclopentyl-2-[(6-methoxy-3-methyl-2-quinolinyl)thio]acetamide	[no description available]	low	0	quinolines
4-(4-morpholinylmethyl)-3-quinolinol	[no description available]	low	0	quinolines
N-(4-hydroxyphenyl)-8-quinolinesulfonamide	[no description available]	low	0	quinolines
[2-(5-methyl-2-thiophenyl)-4-quinolinyl]-(1-pyrrolidinyl)methanone	[no description available]	low	0	quinolines
2-thiophenecarboxylic acid (6-methyl-2-oxo-1H-quinolin-3-yl)methyl ester	[no description available]	low	0	quinolines
N-[6-methyl-1-(2-methylpropyl)-3-pyrazolo[3,4-b]quinolinyl]-2-furancarboxamide	[no description available]	low	0	quinolines
3-[(6-methoxy-4-methyl-2-quinolinyl)thio]propanoic acid	[no description available]	low	0	quinolines
6-methoxy-3-[(3-methylanilino)methyl]-1H-quinolin-2-one	[no description available]	low	0	quinolines
3-[(2,5-dimethylanilino)methyl]-6-methoxy-1H-quinolin-2-one	[no description available]	low	0	quinolines
N-(5-quinolinyl)-2-benzofurancarboxamide	[no description available]	low	0	quinolines
1-(1-pyrrolidinyl)-2-(8-quinolinylthio)ethanone	[no description available]	low	0	quinolines
N-(5-bromo-8-quinolinyl)-5-[(4-chloro-1-pyrazolyl)methyl]-2-furancarboxamide	[no description available]	low	0	organohalogen compound; quinolines
1-[[[2-(2,4-dichlorophenyl)-4-quinolinyl]-oxomethyl]amino]-3-phenylurea	[no description available]	low	0	quinolines
2-[9-(4-methoxyphenyl)-1,8-dioxo-3,4,5,6,7,9-hexahydro-2H-acridin-10-yl]acetic acid	[no description available]	low	0	quinolines
2-(3-bromophenyl)-N-(4,5-dihydrothiazol-2-yl)-4-quinolinecarboxamide	[no description available]	low	0	quinolines
6-chloro-4-phenyl-3-(1-phenyl-5-tetrazolyl)quinoline	[no description available]	low	0	quinolines
2-[3-(4-methoxyphenyl)-1-benzo[f]quinolinyl]acetic acid ethyl ester	[no description available]	low	0	quinolines
[3-bromo-5-thiophen-2-yl-7-(trifluoromethyl)-2-pyrazolo[1,5-a]pyrimidinyl]-(3,4-dihydro-2H-quinolin-1-yl)methanone	[no description available]	low	0	quinolines
2-[2-oxo-2-(2,2,4,6-tetramethyl-1-quinolinyl)ethyl]isoindole-1,3-dione	[no description available]	low	0	quinolines
6-bromo-3-(4-morpholinyl)-4-phenyl-1H-quinolin-2-one	[no description available]	low	0	quinolines
7-chloro-2,3-dihydro-1H-cyclopenta[b]quinoline-9-carboxylic acid	[no description available]	low	0	quinolines
6-ethyl-2-thieno[2,3-b]quinolinecarboxylic acid	[no description available]	low	0	quinolines
N-[4-[(4-methyl-1-piperidinyl)sulfonyl]phenyl]-2-[(4-methyl-[1,2,4]triazolo[4,3-a]quinolin-1-yl)thio]acetamide	[no description available]	low	0	quinolines
2-[(7-methoxy-4-methyl-[1,2,4]triazolo[4,3-a]quinolin-1-yl)thio]-N-methyl-N-(4-phenyl-2-thiazolyl)acetamide	[no description available]	low	0	quinolines
1-cyclopentyl-1-[(5,8-dimethyl-2-oxo-1H-quinolin-3-yl)methyl]-3-ethylthiourea	[no description available]	low	0	quinolines
2-[[[1,3-benzodioxol-5-ylmethyl-[(6-methyl-2-oxo-1H-quinolin-3-yl)methyl]amino]-sulfanylidenemethyl]amino]benzoic acid methyl ester	[no description available]	low	0	quinolines
3-(4-ethoxyphenyl)-1-[2-(4-morpholinyl)ethyl]-1-[(7-oxo-3,6-dihydro-2H-[1,4]dioxino[2,3-g]quinolin-8-yl)methyl]thiourea	[no description available]	low	0	quinolines
1-[(6,7-dimethoxy-2-oxo-1H-quinolin-3-yl)methyl]-3-methyl-1-(thiophen-2-ylmethyl)thiourea	[no description available]	low	0	quinolines
2-[9-(3-chloro-4-methoxyphenyl)-1,8-dioxo-3,4,5,6,7,9-hexahydro-2H-acridin-10-yl]acetic acid	[no description available]	low	0	quinolines
N-[(6-chloro-2-oxo-4-phenyl-1H-quinolin-3-yl)methyl]-4-methylbenzenesulfonamide	[no description available]	low	0	quinolines
N-(2,6-dimethylphenyl)-2-[(6-methoxy-2-methyl-4-quinolinyl)thio]acetamide	[no description available]	low	0	quinolines
2-[(3-cyano-6-methoxy-2-quinolinyl)thio]-N-(2-methyl-1,3-benzothiazol-5-yl)acetamide	[no description available]	low	0	quinolines
1-(6-methoxy-2,2,4-trimethyl-1-quinolinyl)-2-[[5-(4-methylphenyl)-1,3,4-oxadiazol-2-yl]thio]ethanone	[no description available]	low	0	quinolines
1-[(7,8-dimethyl-2-oxo-1H-quinolin-3-yl)methyl]-1-(2-furanylmethyl)-3-(2-methoxyphenyl)thiourea	[no description available]	low	0	quinolines
10-(4-methoxyphenyl)-3,4,5,6,7,9-hexahydro-2H-acridine-1,8-dione	[no description available]	low	0	quinolines
3-[[[2-(3-methylphenyl)-4-quinolinyl]-oxomethyl]amino]-2-thiophenecarboxylic acid methyl ester	[no description available]	low	0	quinolines
1-benzimidazolyl-[2-(4-methoxyphenyl)-4-quinolinyl]methanone	[no description available]	low	0	quinolines
N-(1,3-benzothiazol-2-yl)-2-(3-methoxyphenyl)-4-quinolinecarboxamide	[no description available]	low	0	quinolines
2-(4-ethylphenyl)-N-(4-methyl-1-piperazinyl)-4-quinolinecarboxamide	[no description available]	low	0	quinolines
LSM-27108	[no description available]	low	0	quinolines
[2-(4-propylphenyl)-4-quinolinyl]-[4-(2-pyridinyl)-1-piperazinyl]methanone	[no description available]	low	0	quinolines
2-(4-propylphenyl)-N-[2-(4-sulfamoylphenyl)ethyl]-4-quinolinecarboxamide	[no description available]	low	0	quinolines
2-(3-bromophenyl)-6-methyl-N-(1,2,4-triazol-4-yl)-4-quinolinecarboxamide	[no description available]	low	0	quinolines
N-(1,3-benzodioxol-5-yl)-6-methyl-2-(2-pyridinyl)-4-quinolinecarboxamide	[no description available]	low	0	quinolines
[4-[(2-chlorophenyl)methyl]-1-piperazinyl]-(6,8-dimethyl-2-pyridin-4-yl-4-quinolinyl)methanone	[no description available]	low	0	quinolines
2-[[5-[(2-methyl-8-quinolinyl)oxymethyl]-4-prop-2-enyl-1,2,4-triazol-3-yl]thio]acetamide	[no description available]	low	0	quinolines
2-phenyl-N-(4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl)-4-quinolinecarboxamide	[no description available]	low	0	quinolines
N-(4-fluorophenyl)-3-([1,2,4]triazolo[4,3-a]quinolin-1-ylthio)propanamide	[no description available]	low	0	quinolines
9-(3-bromo-4-hydroxyphenyl)-10-phenyl-3,4,5,6,7,9-hexahydro-2H-acridine-1,8-dione	[no description available]	low	0	quinolines
[2-(4-methoxyphenyl)-6-methyl-4-quinolinyl]-(4-morpholinyl)methanone	[no description available]	low	0	quinolines
7-[4-(4-acetamidophenyl)sulfonyl-1-piperazinyl]-1-ethyl-6-fluoro-4-oxo-3-quinolinecarboxylic acid	[no description available]	low	0	quinolines
N-[6-methoxy-1-(2-methylpropyl)-3-pyrazolo[3,4-b]quinolinyl]-3-methylbutanamide	[no description available]	low	0	quinolines
2-(8-methoxy-2-methyl-4-oxo-1-quinolinyl)-N-(2-methoxyphenyl)acetamide	[no description available]	low	0	quinolines
N-[(6-methoxy-2-oxo-1H-quinolin-3-yl)methyl]-N-propan-2-yl-2-furancarboxamide	[no description available]	low	0	quinolines
1-[2-(3,4-dimethoxyphenyl)ethyl]-1-[(5,7-dimethyl-2-oxo-1H-quinolin-3-yl)methyl]-3-methylthiourea	[no description available]	low	0	quinolines
8,9-dimethyl-N-(3-methylphenyl)-3-[2-(4-morpholinyl)ethyl]-4H-[1,3]thiazino[6,5-b]quinolin-2-imine	[no description available]	low	0	quinolines
6-[[2-(4-morpholinyl)-2-oxoethyl]thio]-[1,3]dioxolo[4,5-g]quinoline-7-carbonitrile	[no description available]	low	0	quinolines
N-[(6-methoxy-2-oxo-1H-quinolin-3-yl)methyl]-N-(2-phenylethyl)acetamide	[no description available]	low	0	quinolines
N-[(4-fluorophenyl)methyl]-N-[(8-methyl-2-oxo-1H-quinolin-3-yl)methyl]-4-morpholinecarboxamide	[no description available]	low	0	quinolines
4-methyl-N-[(2-methyl-4-quinolinyl)methyl]-3-nitrobenzamide	[no description available]	low	0	quinolines
2-(3,5-dimethyl-4-nitro-1-pyrazolyl)-N-[(2-methyl-4-quinolinyl)methyl]acetamide	[no description available]	low	0	quinolines
2-phenyl-N-[4-(2-thiazolylsulfamoyl)phenyl]-4-quinolinecarboxamide	[no description available]	low	0	quinolines
1-ethyl-3-[[[2-(2-methylpropyl)-4-quinolinyl]-oxomethyl]amino]thiourea	[no description available]	low	0	quinolines
2-[6-bromo-4-(2-chlorophenyl)-2-oxo-1H-quinolin-3-yl]acetic acid	[no description available]	low	0	quinolines
3-cyclohexyl-10-methyl-2-thiophen-2-ylpyrimido[4,5-b]quinoline-4,5-dione	[no description available]	low	0	quinolines
2-(4-fluorophenyl)-3-(2-furanylmethyl)-10-methylpyrimido[4,5-b]quinoline-4,5-dione	[no description available]	low	0	quinolines
N-(1-ethyl-6-methyl-3-pyrazolo[3,4-b]quinolinyl)-2-(4-methoxyphenyl)acetamide	[no description available]	low	0	quinolines
N-[3-(2-methoxyphenyl)-1-methyl-4-oxo-2-quinolinyl]-2-methylpropanamide	[no description available]	low	0	quinolines
N-(1,3-benzodioxol-5-ylmethyl)-8-quinolinesulfonamide	[no description available]	low	0	quinolines
1-(1,3-benzodioxol-5-ylmethylthio)-[1,2,4]triazolo[4,3-a]quinoline	[no description available]	low	0	quinolines
N-(4,5-dihydrothiazol-2-yl)-2-thiophen-2-yl-4-quinolinecarboxamide	[no description available]	low	0	quinolines
2-(4-methoxyphenyl)-4-quinolinecarboxylic acid [2-oxo-2-(propan-2-ylamino)ethyl] ester	[no description available]	low	0	quinolines
2-(2-furanyl)-4-quinolinecarboxylic acid [2-[4-amino-1-methyl-3-(2-methylpropyl)-2,6-dioxo-5-pyrimidinyl]-2-oxoethyl] ester	[no description available]	low	0	quinolines
1-cyclopropyl-7-[4-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-1-piperazinyl]-6-fluoro-4-oxo-3-quinolinecarboxylic acid	[no description available]	low	0	quinolines
N-[5-(ethylthio)-1,3,4-thiadiazol-2-yl]-2-quinolinecarboxamide	[no description available]	low	0	quinolines
N-(3-acetyl-2-methyl-5-benzofuranyl)-N-(8-quinolinylsulfonyl)acetamide	[no description available]	low	0	quinolines
N-[3-(6-methyl-4-phenyl-2-quinolinyl)phenyl]methanesulfonamide	[no description available]	low	0	quinolines
2-[3-[(4-chlorophenyl)-oxomethyl]-6-methoxy-4-oxo-1-quinolinyl]-N-(4-fluorophenyl)acetamide	[no description available]	low	0	aromatic ketone; quinolines
5-[(4-fluorophenyl)methyl]-7-(4-methylphenyl)sulfonyl-[1,3]dioxolo[4,5-g]quinolin-8-one	[no description available]	low	0	quinolines
[9-(4-ethoxyphenyl)sulfonyl-2,3-dihydro-[1,4]dioxino[2,3-g]quinolin-8-yl]-(4-methylphenyl)methanone	[no description available]	low	0	aromatic ketone; quinolines
2-[[5-(5-chloro-2-thiophenyl)-1,3,4-oxadiazol-2-yl]thio]-1-(3,4-dihydro-2H-quinolin-1-yl)ethanone	[no description available]	low	0	quinolines
2-quinolinecarboxylic acid (4-oxo-1,2,3-benzotriazin-3-yl)methyl ester	[no description available]	low	0	quinolines
3,4-dihydro-2H-quinolin-1-yl-(4-propoxyphenyl)methanone	[no description available]	low	0	quinolines
N-(5-tert-butyl-3-isoxazolyl)-7-chloro-8-methyl-2-(2-pyridinyl)-4-quinolinecarboxamide	[no description available]	low	0	quinolines
6-bromo-N-(5-ethyl-1,3,4-thiadiazol-2-yl)-2-(2-pyridinyl)-4-quinolinecarboxamide	[no description available]	low	0	quinolines
8-quinolinecarboxylic acid phenyl ester	[no description available]	low	0	quinolines
1-[4-(5-fluoro-1,2-benzoxazol-3-yl)-1-piperidinyl]-2-[(4-methyl-2-quinolinyl)thio]ethanone	[no description available]	low	0	quinolines
8-[2-(4-chloro-3,5-dimethylphenoxy)ethoxy]quinoline	[no description available]	low	0	quinolines
8-[2-(4-chloro-2,5-dimethylphenoxy)ethoxy]quinoline	[no description available]	low	0	quinolines
8-[3-(3,4-dimethylphenoxy)propoxy]quinoline	[no description available]	low	0	quinolines
2-(4-methoxyphenyl)-N-[2-(4-morpholinyl)ethyl]-4-quinolinecarboxamide	[no description available]	low	0	quinolines
1-[(7-chloro-4-quinolinyl)amino]-3-(2,4-dichlorophenyl)thiourea	[no description available]	low	0	organochlorine compound; quinolines
N-[4-[(4,6-dimethyl-2-pyrimidinyl)sulfamoyl]phenyl]-2-phenyl-4-quinolinecarboxamide	[no description available]	low	0	quinolines
3-[2-(4-fluorophenyl)-4-quinolinyl]-6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepine	[no description available]	low	0	quinolines
2-(2-chlorophenyl)-N-[4-[(3,4-dimethyl-5-isoxazolyl)sulfamoyl]phenyl]-4-quinolinecarboxamide	[no description available]	low	0	quinolines
N-(2-cyanophenyl)-2-[(5,7-dibromo-8-quinolinyl)oxy]acetamide	[no description available]	low	0	organohalogen compound; quinolines
5-bromo-2-furancarboxylic acid [2-(3,4-dihydro-2H-quinolin-1-yl)-2-oxoethyl] ester	[no description available]	low	0	quinolines
3-[2-(4-chlorophenyl)-4-quinolinyl]-6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepine	[no description available]	low	0	quinolines
4-[4-(2,3,5,6-Tetramethylphenyl)sulfonylpiperazine-1-carbonyl]-1H-quinolin-2-one	[no description available]	low	0	quinolines	anticoronaviral agent
N-(5-methyl-1,3,4-thiadiazol-2-yl)-2-quinolinecarboxamide	[no description available]	low	0	quinolines
4,6,8-trimethyl-1H-quinoline-2-thione	[no description available]	low	0	quinolines
4-[4-(2,3-Dimethylphenyl)piperazine-1-carbonyl]-1H-quinolin-2-one	[no description available]	low	0	quinolines	anticoronaviral agent
4-[4-[3-(Trifluoromethyl)phenyl]piperazine-1-carbonyl]-1H-quinolin-2-one	[no description available]	low	0	quinolines	anticoronaviral agent
4-ethyl-3-[2-(4-methylphenyl)-4-quinolinyl]-1H-1,2,4-triazole-5-thione	[no description available]	low	0	quinolines
1-(2-benzofuranyl)-2-[(4-methyl-2-quinolinyl)thio]ethanone	[no description available]	low	0	quinolines
N-[2-(2-Methoxyphenoxy)ethyl]-2-oxo-1H-quinoline-4-carboxamide	[no description available]	low	0	quinolines	anticoronaviral agent
2-phenyl-N-(2-piperidin-1-ylethyl)quinolin-4-amine	[no description available]	low	0	quinolines
6-(4-methoxybenzyl)-3-methyl-5,6,7,8-tetrahydroquinoline	[no description available]	low	0	quinolines
8-methoxy-4-oxo-1H-quinoline-2-carboxylic acid methyl ester	[no description available]	low	0	quinolines
N-(2-quinolinyl)cyclohexanecarboxamide	[no description available]	low	0	quinolines
LSM-28160	[no description available]	low	0	quinolines
2-(3,4-dimethoxyphenyl)quinoline	[no description available]	low	0	quinolines
N-[2-[[2-(trifluoromethyl)-4-quinolinyl]thio]ethyl]methanesulfonamide	[no description available]	low	0	quinolines
5-nitro-8-(1-pyrrolidinyl)quinoline	[no description available]	low	0	nitro compound; quinolines
8-(2,3-dihydroxy-3-methylbutoxy)-4-methoxy-1-methyl-2-quinolinone	[no description available]	low	0	quinolines
4-Methoxy-1-methyl-8-((2,2,5,5-tetramethyl-1,3-dioxolan-4-yl)methoxy)quinolin-2(1H)-one	[no description available]	low	0	quinolines
2-[4-(2,2-dimethyl-4-oxo-1,3,5,6-tetrahydrobenzo[a]phenanthridin-5-yl)-2-methoxyphenoxy]acetic acid	[no description available]	low	0	quinolines
1-[8-chloro-4-(1-naphthalenyl)-3,3a,4,9b-tetrahydrocyclopenta[c]quinolin-5-yl]ethanone	[no description available]	low	0	quinolines
7,7-dimethyl-1-(4-methylphenyl)-2,5-dioxo-N-(2-oxo-3-thiolanyl)-6,8-dihydroquinoline-3-carboxamide	[no description available]	low	0	quinolines
N-(5-tert-butyl-1,3,4-thiadiazol-2-yl)-2-phenyl-4-quinolinecarboxamide	[no description available]	low	0	quinolines
1-(8-quinolinylsulfonyl)-3-piperidinecarboxylic acid ethyl ester	[no description available]	low	0	quinolines
N-ethyl-N-[2-[(5-nitro-8-quinolinyl)amino]ethyl]benzenesulfonamide	[no description available]	low	0	nitro compound; quinolines
2,5-dimethoxy-n-(quinolin-3-yl)benzenesulfonamide	[no description available]	low	0	quinolines
N-(4-carbamoylphenyl)-2-(4-methoxyphenyl)-4-quinolinecarboxamide	[no description available]	low	0	quinolines
4-ethoxy-N-(3-quinolinyl)benzenesulfonamide	[no description available]	low	0	quinolines
[2-(3-chlorophenyl)-4-quinolinyl]-[4-(2-pyridinyl)-1-piperazinyl]methanone	[no description available]	low	0	quinolines
[4-(benzenesulfonyl)-1-piperazinyl]-[6-bromo-2-(2-pyridinyl)-4-quinolinyl]methanone	[no description available]	low	0	quinolines
5-chloro-7-[3-pyridinyl-(2-pyridinylamino)methyl]-8-quinolinol	[no description available]	low	0	organochlorine compound; quinolines
6-[[4-(3,4-dihydro-2H-quinolin-1-ylsulfonyl)anilino]-oxomethyl]-1-cyclohex-3-enecarboxylic acid	[no description available]	low	0	quinolines
cb 7969312	[no description available]	low	0	organochlorine compound; quinolines
LSM-18518	[no description available]	low	0	quinolines
3-methyl-N-[[(2-methyl-5-quinolinyl)amino]-sulfanylidenemethyl]benzamide	[no description available]	low	0	quinolines
2-quinolinecarboxylic acid (2-oxo-3-oxolanyl) ester	[no description available]	low	0	quinolines
3-(3,4-dihydro-2H-quinolin-1-ylmethyl)-6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepine	[no description available]	low	0	quinolines
[4-(2-pyridinyl)-1-piperazinyl]-[2-(3,4,5-trimethoxyphenyl)-4-quinolinyl]methanone	[no description available]	low	0	quinolines
2-(2-furanyl)-N-(2-oxolanylmethyl)-4-quinolinecarboxamide	[no description available]	low	0	quinolines
2-(3,4-dimethoxyphenyl)-4-quinolinecarboxylic acid (2-oxo-3-oxolanyl) ester	[no description available]	low	0	quinolines
1-[1-chloro-2-[(2-nitrophenyl)thio]-4-phenyl-2,3,3a,4,5,9b-hexahydro-1H-cyclopenta[c]quinolin-8-yl]ethanone	[no description available]	low	0	quinolines
4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline	[no description available]	low	0	quinolines
4-(6-bromo-1,3-benzodioxol-5-yl)-7,9-dimethyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline	[no description available]	low	0	quinolines
1-[4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolin-8-yl]ethanone	[no description available]	low	0	quinolines
N'-[2-[(6-methoxy-2-methyl-4-quinolinyl)thio]-1-oxoethyl]-2-(1-naphthalenyloxy)acetohydrazide	[no description available]	low	0	quinolines
9-(2-ethoxy-3-methoxyphenyl)-3,6,8,9-tetrahydro-2H-[1,4]dioxino[2,3-g]quinolin-7-one	[no description available]	low	0	quinolines
2-(1,5-dimethyl-4-pyrazolyl)-4-quinolinecarboxylic acid	[no description available]	low	0	quinolines
1-[(5,8-dimethyl-2-oxo-1H-quinolin-3-yl)methyl]-1-(2-furanylmethyl)-3-(2-oxolanylmethyl)thiourea	[no description available]	low	0	quinolines
1-[2-(dimethylamino)ethyl]-1-[(6-oxo-5H-[1,3]dioxolo[4,5-g]quinolin-7-yl)methyl]-3-(2-oxolanylmethyl)thiourea	[no description available]	low	0	quinolines
3-ethyl-1-(2-furanylmethyl)-1-[(7-oxo-3,6-dihydro-2H-[1,4]dioxino[2,3-g]quinolin-8-yl)methyl]thiourea	[no description available]	low	0	quinolines
1-[2-(diethylamino)ethyl]-1-[(7-oxo-3,6-dihydro-2H-[1,4]dioxino[2,3-g]quinolin-8-yl)methyl]-3-(2-oxolanylmethyl)thiourea	[no description available]	low	0	quinolines
1-[(6,7-dimethoxy-2-oxo-1H-quinolin-3-yl)methyl]-1-[2-(3-methylphenyl)ethyl]-3-[3-(4-morpholinyl)propyl]thiourea	[no description available]	low	0	quinolines
N-[(6-methoxy-2-oxo-1H-quinolin-3-yl)methyl]-5-methyl-N-(thiophen-2-ylmethyl)-2,1,3-benzothiadiazole-4-sulfonamide	[no description available]	low	0	quinolines
3-butan-2-yl-1-[(6,7-dimethoxy-2-oxo-1H-quinolin-3-yl)methyl]-1-(2-phenylethyl)thiourea	[no description available]	low	0	quinolines
2-[(3,6-dimethyl-2-quinolinyl)thio]-1-(2-methyl-2,3-dihydroindol-1-yl)ethanone	[no description available]	low	0	quinolines
3-(2,4-dimethoxyphenyl)-1-[(1-ethyl-2-pyrrolidinyl)methyl]-1-[(7-methyl-2-oxo-1H-quinolin-3-yl)methyl]thiourea	[no description available]	low	0	quinolines
4-ethoxy-N-[(6-methoxy-2-oxo-1H-quinolin-3-yl)methyl]-N-[(4-methoxyphenyl)methyl]benzamide	[no description available]	low	0	quinolines
3-(4-fluorophenyl)-1-[(6-oxo-5H-[1,3]dioxolo[4,5-g]quinolin-7-yl)methyl]-1-(thiophen-2-ylmethyl)urea	[no description available]	low	0	quinolines
2-[(3-cyano-8-methyl-2-quinolinyl)thio]-N-(2-oxolanylmethyl)acetamide	[no description available]	low	0	quinolines
N-(2,4-dioxo-1H-pyrimidin-5-yl)-2-[(3-ethyl-5,8-dimethyl-2-quinolinyl)thio]acetamide	[no description available]	low	0	quinolines
N-[2-(cyclohexylamino)-2-oxo-1-(6-quinolinyl)ethyl]-N-[(4-fluorophenyl)methyl]-2,3-dihydro-1,4-benzodioxin-6-carboxamide	[no description available]	low	0	quinolines
3,4-dihydro-2H-quinolin-1-yl-[4-(phenylmethyl)-5-thieno[3,2-b]pyrrolyl]methanone	[no description available]	low	0	quinolines
4-[2-(3,4-dihydro-2H-quinolin-1-yl)-2-oxoethyl]-2-methyl-5-furo[3,2-b]pyrrolecarboxylic acid methyl ester	[no description available]	low	0	quinolines
6-[(2-methoxyphenyl)methylsulfamoyl]-4-oxo-1H-quinoline-3-carboxylic acid	[no description available]	low	0	quinolines
2-[(3,5-dimethyl-4-isoxazolyl)methylthio]-4-ethyl-7,7-dimethyl-5-oxo-6,8-dihydroquinoline-3-carbonitrile	[no description available]	low	0	quinolines
4-[(1-methyl-2-oxo-4-quinolinyl)oxy]-N-(4-methyl-2-pyridinyl)butanamide	[no description available]	low	0	quinolines
N-[2-(6,7-dimethyl-2-oxo-1H-quinolin-3-yl)ethyl]-1-propanesulfonamide	[no description available]	low	0	quinolines
N-[2-(6,7-dimethyl-2-oxo-1H-quinolin-3-yl)ethyl]ethanesulfonamide	[no description available]	low	0	quinolines
N-(2-methyl-4-oxo-1-propyl-6-quinolinyl)-2-pyrazinecarboxamide	[no description available]	low	0	quinolines
3,4-dihydro-2H-quinolin-1-yl-(7-methoxy-4,5-dihydrobenzo[g][1,2]benzoxazol-3-yl)methanone	[no description available]	low	0	quinolines
4,5-dihydrobenzo[g][1,2]benzoxazol-3-yl(3,4-dihydro-2H-quinolin-1-yl)methanone	[no description available]	low	0	quinolines
9-(4-methoxyphenyl)-3,3,6,6-tetramethyl-10-[2-(4-morpholinyl)ethyl]-4,5,7,9-tetrahydro-2H-acridine-1,8-dione	[no description available]	low	0	quinolines
2-(2,4-dimethoxyanilino)-N-[3-(4-methyl-1-piperazinyl)propyl]-4-quinolinecarboxamide	[no description available]	low	0	quinolines
1-[oxo-[4-oxo-6-[(4-propan-2-ylphenyl)sulfamoyl]-1H-quinolin-3-yl]methyl]-4-piperidinecarboxamide	[no description available]	low	0	aromatic amide; quinolines
[4-[6-(4-morpholinyl)-3-pyridazinyl]-1-piperazinyl]-(2-pyridin-4-yl-4-quinolinyl)methanone	[no description available]	low	0	quinolines
5-bromo-N-[2-(6,7-dimethyl-2-oxo-1H-quinolin-3-yl)ethyl]-2-furancarboxamide	[no description available]	low	0	quinolines
6-[(2-ethylphenyl)sulfamoyl]-N-(2-furanylmethyl)-4-oxo-1H-quinoline-3-carboxamide	[no description available]	low	0	aromatic amide; quinolines
N-ethyl-3-[4-morpholinyl(oxo)methyl]-4-oxo-N-phenyl-1H-quinoline-6-sulfonamide	[no description available]	low	0	aromatic amide; quinolines
2-ethyl-N-[2-(7-methoxy-2-oxo-1H-quinolin-3-yl)ethyl]butanamide	[no description available]	low	0	quinolines
3,4-dihydro-2H-quinolin-1-yl-[5-(4-methoxyphenyl)-3-isoxazolyl]methanone	[no description available]	low	0	quinolines
6-[(2-ethylphenyl)sulfamoyl]-4-oxo-N-(2-oxolanylmethyl)-1H-quinoline-3-carboxamide	[no description available]	low	0	aromatic amide; quinolines
N-(1,3-benzodioxol-5-yl)-2-[(1-ethyl-2-oxo-4-quinolinyl)thio]acetamide	[no description available]	low	0	quinolines
6-(1-azepanylsulfonyl)-1-ethyl-N-(2-furanylmethyl)-4-oxo-3-quinolinecarboxamide	[no description available]	low	0	aromatic amide; quinolines
N-[2-(7-methoxy-2-oxo-1H-quinolin-3-yl)ethyl]cyclopropanecarboxamide	[no description available]	low	0	quinolines
N-[3-(3,5-dimethyl-1-piperidinyl)propyl]-2-[(1-methyl-2-oxo-4-quinolinyl)oxy]acetamide	[no description available]	low	0	quinolines
1-acetyl-N-propyl-3,4-dihydro-2H-quinoline-6-sulfonamide	[no description available]	low	0	quinolines
2-(2,5-dimethoxyanilino)-N-[3-(4-morpholinyl)propyl]-4-quinolinecarboxamide	[no description available]	low	0	quinolines
3-acetyl-6-methyl-1H-quinolin-4-one	[no description available]	low	0	quinolines
2-amino-4-[4-(methylthio)phenyl]-5-oxo-1-phenyl-4,6,7,8-tetrahydroquinoline-3-carbonitrile	[no description available]	low	0	quinolines
N-[1-(2,3-dihydro-1,4-benzodioxin-6-yl)ethyl]-1-methyl-4-oxo-6-(1-pyrrolidinylsulfonyl)-3-quinolinecarboxamide	[no description available]	low	0	aromatic amide; quinolines
N-butan-2-yl-6-[(4-ethoxyphenyl)sulfamoyl]-4-oxo-1H-quinoline-3-carboxamide	[no description available]	low	0	aromatic amide; quinolines
1-methyl-6-[(4-methyl-1-piperidinyl)sulfonyl]-3-[oxo(1-piperidinyl)methyl]-4-quinolinone	[no description available]	low	0	aromatic amide; quinolines
1-methyl-N-(2-methylcyclohexyl)-4-oxo-6-(1-pyrrolidinylsulfonyl)-3-quinolinecarboxamide	[no description available]	low	0	aromatic amide; quinolines
8-(2-propoxyphenyl)-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]quinolin-6-one	[no description available]	low	0	quinolines
2,6-dimethyl-4-(4-phenyl-2-quinolinyl)morpholine	[no description available]	low	0	quinolines
quinoxyfen	[no description available]	low	0	aromatic ether; monofluorobenzenes; organochlorine compound; quinolines	antifungal agrochemical
N-[4-(methoxymethyl)-6-methyl-2-oxo-1H-quinolin-7-yl]cyclopropanecarboxamide	[no description available]	low	0	quinolines
N-[2-(4-morpholinyl)ethyl]-2-(4-propan-2-yloxyphenyl)-4-quinolinecarboxamide	[no description available]	low	0	quinolines
5-chloro-7-[1-piperidinyl(2-pyridinyl)methyl]-8-quinolinol	[no description available]	low	0	organochlorine compound; quinolines
4-(3,4-dihydro-2H-quinolin-1-ylsulfonyl)-N-(5-ethyl-1,3,4-oxadiazol-2-yl)benzamide	[no description available]	low	0	quinolines
5-chloro-7-[(4-ethyl-1-piperazinyl)-(3-pyridinyl)methyl]-8-quinolinol	[no description available]	low	0	organochlorine compound; quinolines
N-[2-(6,7-dimethyl-2-oxo-1H-quinolin-3-yl)ethyl]-2-thiophenecarboxamide	[no description available]	low	0	quinolines
6-bromo-2-(4-methylphenyl)-N-[(1-methyl-4-pyrazolyl)methyl]-4-quinolinecarboxamide	[no description available]	low	0	quinolines
3-acetyl-6-bromo-2-methyl-4-quinolinecarboxylic acid	[no description available]	low	0	quinolines
2-thiophen-2-yl-4-quinolinecarboxylic acid (2-oxo-3-oxolanyl) ester	[no description available]	low	0	quinolines
6,8-dibromo-2-thiophen-2-ylquinoline	[no description available]	low	0	organohalogen compound; quinolines
N-(4-methylphenyl)-2-oxo-3,4-dihydro-1H-quinoline-6-sulfonamide	[no description available]	low	0	quinolines
2-(4-methoxyphenyl)-N-[2-(4-morpholinyl)-5-(4-morpholinylsulfonyl)phenyl]-4-quinolinecarboxamide	[no description available]	low	0	quinolines
N-(3-methylbutyl)-6-(4-morpholinylsulfonyl)-2-pyridin-4-yl-4-quinolinecarboxamide	[no description available]	low	0	quinolines
2-(4-ethoxyphenyl)-N-[3-(1-imidazolyl)propyl]-4-quinolinecarboxamide	[no description available]	low	0	quinolines
7-ethoxy-3-[5-(2-furanyl)-2-methylsulfonyl-3,4-dihydropyrazol-3-yl]-1H-quinolin-2-one	[no description available]	low	0	quinolines
2-amino-4-(5-bromo-2-thiophenyl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile	[no description available]	low	0	quinolines
N-[(5-quinolinylamino)-sulfanylidenemethyl]benzamide	[no description available]	low	0	quinolines
7-[(3-hydroxy-3,4-dihydro-2H-benzo[h]quinolin-1-yl)methyl]-5-thiazolo[3,2-a]pyrimidinone	[no description available]	low	0	quinolines
N-(3,5-dichloro-2-pyridinyl)-2-[(4-methyl-2-quinolinyl)thio]propanamide	[no description available]	low	0	quinolines
2-amino-1-(dimethylamino)-4-(1-naphthalenyl)-5-oxo-7-phenyl-4,6,7,8-tetrahydroquinoline-3-carbonitrile	[no description available]	low	0	naphthalenes; quinolines
2-(2-chlorophenyl)-N-[3-(3,4,5,6-tetrahydro-2H-azepin-7-ylsulfamoyl)phenyl]-4-quinolinecarboxamide	[no description available]	low	0	quinolines
2-phenyl-4-quinolinecarboxylic acid [2-[2-chloro-5-(dimethylsulfamoyl)anilino]-2-oxoethyl] ester	[no description available]	low	0	quinolines
2-amino-4-(3,4-dimethoxyphenyl)-7,7-dimethyl-5-oxo-1-(3-pyridinyl)-6,8-dihydro-4H-quinoline-3-carbonitrile	[no description available]	low	0	quinolines
2-(1-naphthalenyl)-4-quinolinecarboxylic acid [1-[(1,5-dimethyl-3-oxo-2-phenyl-4-pyrazolyl)amino]-1-oxopropan-2-yl] ester	[no description available]	low	0	naphthalenes; quinolines
2-(5-bromo-2-thiophenyl)-N-(4-methyl-1-piperazinyl)-4-quinolinecarboxamide	[no description available]	low	0	quinolines
[3,5-bis(difluoromethyl)-5-hydroxy-4H-pyrazol-1-yl]-[2-(4-propan-2-ylphenyl)-4-quinolinyl]methanone	[no description available]	low	0	quinolines
[2-(3,4-dimethylphenyl)-4-quinolinyl]-(1-piperidinyl)methanone	[no description available]	low	0	quinolines
sb 408124	[no description available]	low	0	organohalogen compound; quinolines
2-(4-fluorophenyl)-4-quinolinecarboxylic acid [2-oxo-2-(2-oxolanylmethylamino)ethyl] ester	[no description available]	low	0	quinolines
5-[3-(2-chloro-6-methoxy-3-quinolinyl)-5-(2-furanyl)-3,4-dihydropyrazol-2-yl]-5-oxopentanoic acid	[no description available]	low	0	organochlorine compound; quinolines
[3-(2-chloro-6-ethoxy-3-quinolinyl)-5-phenyl-3,4-dihydropyrazol-2-yl]-thiophen-2-ylmethanone	[no description available]	low	0	organochlorine compound; quinolines
flosequinan	[no description available]	low	0	quinolines
N-(3,4-dimethylphenyl)-2-oxo-3,4-dihydro-1H-quinoline-6-sulfonamide	[no description available]	low	0	quinolines
1-[(4-fluorophenyl)-oxomethyl]-3-[(5-methyl-[1,2,4]triazolo[4,3-a]quinolin-1-yl)thio]-2-azepanone	[no description available]	low	0	quinolines
7,7-dimethyl-1-(4-methylphenyl)-N-[3-(4-morpholinyl)propyl]-2,5-dioxo-6,8-dihydroquinoline-3-carboxamide	[no description available]	low	0	quinolines
2-(4-bromophenyl)-4-quinolinecarboxylic acid (2-oxo-3-oxolanyl) ester	[no description available]	low	0	quinolines
N-(5-methyl-3-isoxazolyl)-2-(4-propan-2-yloxyphenyl)-4-quinolinecarboxamide	[no description available]	low	0	quinolines
2-methyl-1-cyclopropanecarboxylic acid [5-[2-(3,4-dimethoxyphenyl)-4-quinolinyl]-1,3,4-oxadiazol-2-yl]methyl ester	[no description available]	low	0	quinolines
1-(4-bromophenyl)-1'-methyl-6'-nitro-2'-phenylspiro[1,3-diazinane-5,3'-2,4-dihydroquinoline]-2,4,6-trione	[no description available]	low	0	quinolines
1-phenylspiro[1,3-diazinane-5,5'-2,4,4a,6-tetrahydro-1H-[1,4]oxazino[4,3-a]quinoline]-2,4,6-trione	[no description available]	low	0	quinolines
LSM-4833	[no description available]	low	0	quinolines
1-[[3-(4-chlorophenyl)-4,5-dihydroisoxazol-5-yl]methyl]-4-methyl-2-quinolinone	[no description available]	low	0	quinolines
4-[[2-(4-ethyl-1-piperazinyl)-2-oxoethyl]thio]-1-methyl-2-quinolinone	[no description available]	low	0	quinolines
2-[2-(7-methoxy-2-oxo-1H-quinolin-3-yl)ethyl]isoindole-1,3-dione	[no description available]	low	0	quinolines
montelukast	[no description available]	low	0	aliphatic sulfide; monocarboxylic acid; quinolines	anti-arrhythmia drug; anti-asthmatic drug; leukotriene antagonist
l 660,711	[no description available]	low	0	quinolines
pitavastatin	[no description available]	low	0	cyclopropanes; dihydroxy monocarboxylic acid; monofluorobenzenes; quinolines; statin (synthetic)	antioxidant
1-[(2-oxo-3,4-dihydro-1H-quinolin-6-yl)sulfonyl]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)-4-piperidinecarboxamide	[no description available]	low	0	quinolines
1-(3-amino-7-methoxy-1-pyrazolo[3,4-b]quinolinyl)-2-(2-methoxyphenyl)ethanone	[no description available]	low	0	quinolines
N-(2-ethoxyphenyl)-1-(8-quinolinylsulfonyl)-3-piperidinecarboxamide	[no description available]	low	0	quinolines
N-[2-(1-pyrrolidinyl)ethyl]-8-quinolinesulfonamide	[no description available]	low	0	quinolines
N-[[4-(dimethylamino)phenyl]methyl]-2-[methyl(8-quinolinylsulfonyl)amino]acetamide	[no description available]	low	0	quinolines
N-[(2-methoxyphenyl)methyl]-1-(8-quinolinylsulfonyl)-4-piperidinecarboxamide	[no description available]	low	0	quinolines
evocarpine	[no description available]	low	0	quinolines
4-[(3aR,4S,9bS)-8-[(4-methoxyphenyl)sulfamoyl]-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolin-4-yl]benzoic acid	[no description available]	low	0	quinolines
Bucharaine	[no description available]	low	0	quinolines
bedaquiline	[no description available]	low	0	aromatic ether; naphthalenes; organobromine compound; quinolines; tertiary alcohol; tertiary amino compound	antitubercular agent; ATP synthase inhibitor
1,1'-diethyl-2,2'-cyanine	[no description available]	low	0	1,1'-diethyl-2,2'-cyanine; quinolines
penicillin v	[no description available]	low	0	1,1'-diethyl-2,2'-cyanine; quinolines
salubrinal	[no description available]	low	0	aminal; organochlorine compound; quinolines; secondary carboxamide; thioureas
2-(1-ethyl-4-pyrazolyl)-4-quinolinecarboxylic acid	[no description available]	low	0	quinolines
4-[2-(3,4-dimethoxyphenyl)ethylamino]-2-oxo-1H-quinoline-3-carboxaldehyde	[no description available]	low	0	quinolines
sb 222200	[no description available]	low	0	quinolines
l 689560	[no description available]	low	0	quinolines
sb 218795	[no description available]	low	0	quinolines
1-(3-amino-7-methoxy-1-pyrazolo[3,4-b]quinolinyl)-2-(4-chlorophenyl)ethanone	[no description available]	low	0	quinolines
N-butyl-N-phenyl-8-quinolinesulfonamide	[no description available]	low	0	quinolines
ik 682	[no description available]	low	0	hydroxamic acid; pyrrolidin-2-ones; quinolines
N-(3-methylphenyl)-2-oxo-3,4-dihydro-1H-quinoline-6-sulfonamide	[no description available]	low	0	quinolines
3-butyl-10-phenylpyrimido[4,5-b]quinoline-2,4-dione	[no description available]	low	0	quinolines
N-(4-fluorophenyl)-2-oxo-3,4-dihydro-1H-quinoline-6-sulfonamide	[no description available]	low	0	quinolines
N-[2-(3-methoxyphenyl)-4-[(4-methoxyphenyl)methoxy]-6-quinolinyl]-3-pyridinecarboxamide	[no description available]	low	0	quinolines
pq 401	[no description available]	low	0	quinolines
3-(4-ethoxyphenyl)-1-[3-(4-morpholinyl)propyl]-1-[(1-propyl-3,4-dihydro-2H-quinolin-6-yl)methyl]urea	[no description available]	low	0	quinolines
lenvatinib	[no description available]	low	0	aromatic amide; aromatic ether; cyclopropanes; monocarboxylic acid amide; monochlorobenzenes; phenylureas; quinolines	antineoplastic agent; EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor; fibroblast growth factor receptor antagonist; orphan drug; vascular endothelial growth factor receptor antagonist
ozenoxacin	[no description available]	low	0	quinolines
jte 907	[no description available]	low	0	aromatic amide; quinolines
hki 272	[no description available]	low	0	nitrile; quinolines	antineoplastic agent; tyrosine kinase inhibitor
tan 67	[no description available]	low	0	quinolines
ly-2157299	[no description available]	low	0	aromatic amide; methylpyridines; monocarboxylic acid amide; pyrrolopyrazole; quinolines	antineoplastic agent; TGFbeta receptor antagonist
5-iodo-6-nitro-2-piperazinylquinoline	[no description available]	low	0	nitro compound; quinolines
besifloxacin	[no description available]	low	0	quinolines
ofloxacin n-oxide	[no description available]	low	0	quinolines
crenolanib	[no description available]	low	0	aminopiperidine; aromatic ether; benzimidazoles; oxetanes; quinolines; tertiary amino compound	angiogenesis inhibitor; antineoplastic agent; apoptosis inducer; EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor
ki11502	[no description available]	low	0	aromatic ether; benzamides; quinolines; thioureas	antineoplastic agent; apoptosis inducer; EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor
pf 573228	[no description available]	low	0	quinolines
osi 906	[no description available]	low	0	cyclobutanes; quinolines
dactolisib	[no description available]	low	0	imidazoquinoline; nitrile; quinolines; ring assembly; ureas	antineoplastic agent; EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor; mTOR inhibitor
nemonoxacin	[no description available]	low	0	quinolines
[9-(benzenesulfonyl)-2,3-dihydro-[1,4]dioxino[2,3-g]quinolin-8-yl]-(4-methylphenyl)methanone	[no description available]	low	0	aromatic ketone; quinolines
1-(phenylmethyl)-4-quinolinone	[no description available]	low	0	quinolines
CDN1163	[no description available]	low	0	aromatic ether; quinolines; secondary carboxamide	SERCA activator
3,5-dimethoxy-N-[1-[oxo(thiophen-2-yl)methyl]-3,4-dihydro-2H-quinolin-6-yl]benzamide	[no description available]	low	0	quinolines
picogreen	[no description available]	low	0	benzothiazoles; cyanine dye; quinolines; tertiary amine	fluorescent dye
1-[(1-ethyl-3,4-dihydro-2H-quinolin-6-yl)methyl]-3-(3-methylphenyl)-1-[2-(4-morpholinyl)ethyl]thiourea	[no description available]	low	0	quinolines
1-[(1-ethyl-3,4-dihydro-2H-quinolin-6-yl)methyl]-3-(4-methylphenyl)-1-[2-(4-morpholinyl)ethyl]thiourea	[no description available]	low	0	quinolines
1-[(1-ethyl-3,4-dihydro-2H-quinolin-6-yl)methyl]-3-(3-methoxyphenyl)-1-[2-(4-morpholinyl)ethyl]thiourea	[no description available]	low	0	quinolines
2-[4-[(6-ethoxy-2-quinolinyl)methyl]-1-(3-thiophenylmethyl)-2-piperazinyl]ethanol	[no description available]	low	0	quinolines
nk 5	[no description available]	low	0	organic iodide salt; quinolines	fluorochrome
peniprequinolone	[no description available]	low	0	quinolines
pf 04217903	[no description available]	low	0	quinolines
sgx 523	[no description available]	low	0	aryl sulfide; biaryl; pyrazoles; quinolines; triazolopyridazine	c-Met tyrosine kinase inhibitor; nephrotoxic agent
AMG-208	[no description available]	low	0	aromatic ether; quinolines; triazolopyridazine	antineoplastic agent; c-Met tyrosine kinase inhibitor
lucitanib	[no description available]	low	0	aromatic ether; cyclopropanes; naphthalenecarboxamide; primary amino compound; quinolines	antineoplastic agent; fibroblast growth factor receptor antagonist; vascular endothelial growth factor receptor antagonist
dcc-2036	[no description available]	low	0	organofluorine compound; phenylureas; pyrazoles; pyridinecarboxamide; quinolines	tyrosine kinase inhibitor
cabozantinib	[no description available]	low	0	aromatic ether; dicarboxylic acid diamide; organofluorine compound; quinolines	antineoplastic agent; tyrosine kinase inhibitor
pf 750	[no description available]	low	0	quinolines
gsk 2126458	[no description available]	low	0	aromatic ether; difluorobenzene; pyridazines; pyridines; quinolines; sulfonamide	anticoronaviral agent; antineoplastic agent; autophagy inducer; EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor; mTOR inhibitor; radiosensitizing agent
N-[(8-methoxy-5-nitro-7-quinolinyl)-thiophen-2-ylmethyl]propanamide	[no description available]	low	0	nitro compound; quinolines
iwr-1 endo	[no description available]	low	0	benzamides; bridged compound; dicarboximide; quinolines	axin stabilizer; Wnt signalling inhibitor
jnj38877605	[no description available]	low	0	quinolines
torin 1	[no description available]	low	0	N-acylpiperazine; N-arylpiperazine; organofluorine compound; pyridoquinoline; quinolines	antineoplastic agent; mTOR inhibitor
DMH1	[no description available]	low	0	aromatic ether; pyrazolopyrimidine; quinolines	antineoplastic agent; bone morphogenetic protein receptor antagonist; protein kinase inhibitor
1-butyl-4-hydroxy-N-(3-methyl-2-pyridinyl)-2-oxo-3-quinolinecarboxamide	[no description available]	low	0	aromatic amide; quinolines
4-hydroxy-2-oxo-1-propyl-N-(pyridin-4-ylmethyl)-3-quinolinecarboxamide	[no description available]	low	0	aromatic amide; quinolines
4-hydroxy-1-methyl-3-(phenylthio)-1,2-dihydroquinolin-2-one	[no description available]	low	0	quinolines
LSM-23865	[no description available]	low	0	quinolines
N-[(4-chlorophenyl)methyl]-4-hydroxy-2-oxo-1-prop-2-enyl-3-quinolinecarboxamide	[no description available]	low	0	aromatic amide; quinolines
4-hydroxy-1-methyl-2-oxo-N-(4-oxo-2-propyl-3-quinazolinyl)-3-quinolinecarboxamide	[no description available]	low	0	aromatic amide; quinolines
1-butyl-N-[(4-chlorophenyl)methyl]-4-hydroxy-2-oxo-3-quinolinecarboxamide	[no description available]	low	0	aromatic amide; quinolines
N'-[(2-chlorophenyl)-oxomethyl]-1-ethyl-4-hydroxy-2-oxo-3-quinolinecarbohydrazide	[no description available]	low	0	aromatic amide; quinolines
4-hydroxy-1-methyl-N'-[(3-methylphenyl)-oxomethyl]-2-oxo-3-quinolinecarbohydrazide	[no description available]	low	0	aromatic amide; quinolines
Bucharidine	[no description available]	low	0	quinolines
4-hydroxy-2-oxo-1-prop-2-enyl-N-(3-pyridinyl)-3-quinolinecarboxamide	[no description available]	low	0	aromatic amide; quinolines
LSM-23565	[no description available]	low	0	aromatic amide; quinolines
l 701324	[no description available]	low	0	quinolines
1-ethyl-4-hydroxy-2-oxo-N'-(1-oxoheptyl)-3-quinolinecarbohydrazide	[no description available]	low	0	aromatic amide; quinolines
2-[[[4-hydroxy-2-oxo-1-(phenylmethyl)-3-quinolinyl]-oxomethyl]amino]acetic acid	[no description available]	low	0	quinolines
1-ethyl-4-hydroxy-2-oxo-N'-(1-oxodecyl)-3-quinolinecarbohydrazide	[no description available]	low	0	aromatic amide; quinolines
LSM-31922	[no description available]	low	0	aromatic amide; quinolines
1-ethyl-4-hydroxy-2-oxo-N-(3-pyridinylmethyl)-3-quinolinecarboxamide	[no description available]	low	0	aromatic amide; quinolines
N-(1H-benzimidazol-2-yl)-1-ethyl-4-hydroxy-2-oxo-3-quinolinecarboxamide	[no description available]	low	0	aromatic amide; quinolines
N-[(3,4-dimethoxyphenyl)methyl]-4-hydroxy-2-oxo-1-propyl-3-quinolinecarboxamide	[no description available]	low	0	aromatic amide; quinolines
4-hydroxy-N-(2-methyl-4-oxo-3-quinazolinyl)-1-(2-methylpropyl)-2-oxo-5,6,7,8-tetrahydroquinoline-3-carboxamide	[no description available]	low	0	aromatic amide; quinolines
4-hydroxy-1-(2-methylpropyl)-2-oxo-N-[4-oxo-2-(phenylmethyl)-3-quinazolinyl]-5,6,7,8-tetrahydroquinoline-3-carboxamide	[no description available]	low	0	aromatic amide; quinolines
4-hydroxy-2-oxo-1-pentyl-N-(2-pyridinylmethyl)-3-quinolinecarboxamide	[no description available]	low	0	aromatic amide; quinolines
N-[2-(4-chlorophenyl)ethyl]-4-hydroxy-2-oxo-1-propyl-3-quinolinecarboxamide	[no description available]	low	0	aromatic amide; quinolines
4-hydroxy-1,7,7-trimethyl-3-(2,4,6-trimethylphenyl)-6,8-dihydroquinoline-2,5-dione	[no description available]	low	0	quinolines
sybr green i	[no description available]	low	0	benzothiazolium ion; cyanine dye; quinolines; tertiary amine	fluorescent dye
9-(3,5-dimethoxyphenyl)-1-[4-(1-piperazinyl)-3-(trifluoromethyl)phenyl]-2-benzo[h][1,6]naphthyridinone	[no description available]	low	0	quinolines
GSK1059615	[no description available]	low	0	pyridines; quinolines; thiazolidinone	antineoplastic agent; EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor
benzoic acid	[no description available]	low	0	benzoic acids	algal metabolite; antimicrobial food preservative; drug allergen; EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor; EC 3.1.1.3 (triacylglycerol lipase) inhibitor; human xenobiotic metabolite; plant metabolite
diatrizoic acid	[no description available]	low	0	acetamides; benzoic acids; organoiodine compound	environmental contaminant; radioopaque medium; xenobiotic
aspirin	[no description available]	low	0	benzoic acids; phenyl acetates; salicylates	anticoagulant; antipyretic; cyclooxygenase 1 inhibitor; cyclooxygenase 2 inhibitor; drug allergen; EC 1.1.1.188 (prostaglandin-F synthase) inhibitor; geroprotector; non-narcotic analgesic; non-steroidal anti-inflammatory drug; plant activator; platelet aggregation inhibitor; prostaglandin antagonist; teratogenic agent
bumetanide	[no description available]	low	0	amino acid; benzoic acids; sulfonamide	diuretic; EC 3.6.3.49 (channel-conductance-controlling ATPase) inhibitor
3,4-dihydroxybenzohydroxamic acid	[no description available]	low	0	benzoic acids
fluorescite	[no description available]	low	0	benzoic acids; cyclic ketone; hydroxy monocarboxylic acid; organic heterotricyclic compound; phenols; xanthene dye	fluorescent dye; radioopaque medium
iodamide	[no description available]	low	0	benzoic acids; organoiodine compound	radioopaque medium
iodipamide	[no description available]	low	0	benzoic acids; organoiodine compound; secondary carboxamide	radioopaque medium
ioxaglate	[no description available]	low	0	benzenedicarboxamide; benzoic acids; organoiodine compound	radioopaque medium
nafamostat	[no description available]	low	0	benzoic acids; guanidines
probenecid	[no description available]	low	0	benzoic acids; sulfonamide	uricosuric drug
salicylsalicylic acid	[no description available]	low	0	benzoate ester; benzoic acids; phenols; salicylates	antineoplastic agent; antirheumatic drug; EC 3.5.2.6 (beta-lactamase) inhibitor; hypoglycemic agent; non-narcotic analgesic; non-steroidal anti-inflammatory drug; prodrug
2,3,5-triiodobenzoic acid	[no description available]	low	0	benzoic acids; organoiodine compound	antiauxins
pyromellitic acid	[no description available]	low	0	benzoic acids; tetracarboxylic acid
veratric acid	[no description available]	low	0	benzoic acids	allergen; plant metabolite
sulfosalicylic acid	[no description available]	low	0	arenesulfonic acid; benzoic acids; phenols	metabolite
3,5-dinitrobenzoic acid	[no description available]	low	0	benzoic acids; C-nitro compound
3,4,5-trimethoxybenzoic acid	[no description available]	low	0	benzoic acids; methoxybenzenes	human urinary metabolite; human xenobiotic metabolite; plant metabolite
triflusal	[no description available]	low	0	benzoic acids; carboxylic ester; salicylates
2-trifluoromethylbenzoic acid	[no description available]	low	0	(trifluoromethyl)benzenes; benzoic acids
4-(trifluoromethyl)benzoic acid	[no description available]	low	0	(trifluoromethyl)benzenes; benzoic acids
syringic acid	[no description available]	low	0	benzoic acids; dimethoxybenzene; phenols	plant metabolite
trimesic acid	[no description available]	low	0	benzoic acids; tricarboxylic acid
4-ethylbenzoic acid	[no description available]	low	0	benzoic acids
4-carboxybenzaladehyde	[no description available]	low	0	benzaldehydes; benzoic acids; monocarboxylic acid	plant metabolite
4-(octyloxy)benzoic acid	[no description available]	low	0	benzoic acids
4-[(2,4,6-triamino-5-pyrimidinyl)azo]benzoic acid	[no description available]	low	0	benzoic acids
3-o-methylgallic acid	[no description available]	low	0	benzoic acids; catechols
ioxitalamic acid	[no description available]	low	0	acetamides; benzoic acids; dicarboxylic acid monoamide; organoiodine compound	environmental contaminant; radioopaque medium; xenobiotic
acifluorfen	[no description available]	low	0	aromatic ether; benzoic acids; C-nitro compound; monocarboxylic acid; organochlorine compound; organofluorine compound	agrochemical; EC 1.3.3.4 (protoporphyrinogen oxidase) inhibitor; herbicide
4-aminomethylbenzoic acid	[no description available]	low	0	benzoic acids
phenolphthalein	[no description available]	low	0	benzoic acids
2-iodosobenzoic acid	[no description available]	low	0	benzoic acids; organoiodine compound	EC 4.3.1.15 (diaminopropionate ammonia-lyase) inhibitor
tosiben	[no description available]	low	0	benzoic acids; carboxylic ester; salicylates
4-benzyloxybenzoic acid	[no description available]	low	0	benzoic acids
bexarotene	[no description available]	low	0	benzoic acids; naphthalenes; retinoid	antineoplastic agent
primisulfuron	[no description available]	low	0	benzoic acids
valerylsalicylate	[no description available]	low	0	benzoic acids; salicylates; valerate ester	cyclooxygenase 1 inhibitor
salicylic acid glucoside	[no description available]	low	0	benzoic acids; D-glucoside; monosaccharide derivative
4-guanidinobenzoate	[no description available]	low	0	benzoic acids; guanidines
deferasirox	[no description available]	low	0	benzoic acids; monocarboxylic acid; phenols; triazoles	iron chelator
bispyribac	[no description available]	low	0	aromatic ether; benzoic acids; monocarboxylic acid; pyrimidines	herbicide
1-[4-carboxy-2-(3-pentylamino)phenyl]-5,5-bis(hydroxymethyl)pyrrolidin-2-one	[no description available]	low	0	benzoic acids; primary alcohol; pyrrolidin-2-ones; secondary amino compound
3-(1-azepanylazo)benzoic acid	[no description available]	low	0	benzoic acids
4-[[dimethoxyphosphoryl(phenyl)methyl]amino]benzoic acid	[no description available]	low	0	benzoic acids
ly382884	[no description available]	low	0	benzoic acids
3-benzamido-3-oxopropanethioic acid S-methyl ester	[no description available]	low	0	benzoic acids
N-[(2-phenylethylamino)-sulfanylidenemethyl]benzamide	[no description available]	low	0	benzoic acids
n-benzamidothiourea	[no description available]	low	0	benzoic acids
N-[[(4,6-dimethyl-2-pyrimidinyl)amino]-sulfanylidenemethyl]benzamide	[no description available]	low	0	benzoic acids
2-[2-[[benzamido(sulfanylidene)methyl]amino]-4-thiazolyl]acetic acid ethyl ester	[no description available]	low	0	benzoic acids
3-ethoxy-N-[(3-pyridinylamino)-sulfanylidenemethyl]benzamide	[no description available]	low	0	benzoic acids
2-[(2-chlorophenoxy)methyl]benzoic acid	[no description available]	low	0	benzoic acids
N'-[2-[(4,5-dimethyl-1,2,4-triazol-3-yl)thio]-1-oxoethyl]-4-methoxybenzohydrazide	[no description available]	low	0	benzoic acids
2-(2-cyclohexylidenehydrazinyl)benzoic acid	[no description available]	low	0	benzoic acids
N-(3,4-dimethyl-2-thiazolylidene)benzamide	[no description available]	low	0	benzoic acids
4-methoxy-N-[[(phenylmethyl)amino]-sulfanylidenemethyl]benzamide	[no description available]	low	0	benzoic acids
(3-amino-1,2,4-triazol-4-yl)-(2,5-dimethylphenyl)methanone	[no description available]	low	0	benzoic acids
3-[[[5-(phenylmethyl)-1,3,4-oxadiazol-2-yl]thio]methyl]benzoic acid	[no description available]	low	0	benzoic acids
N-[(4-methoxyphenyl)-oxomethyl]-1-piperidinecarboxamide	[no description available]	low	0	benzoic acids
1-[[[2-(difluoromethoxy)phenyl]-oxomethyl]amino]-3-(4-fluorophenyl)thiourea	[no description available]	low	0	benzoic acids
1-[[[2-(difluoromethoxy)phenyl]-oxomethyl]amino]-3-(3-methylphenyl)thiourea	[no description available]	low	0	benzoic acids
N-[[(5-methyl-1H-pyrazol-3-yl)amino]-oxomethyl]-3-(1,1,2,2-tetrafluoroethoxy)benzamide	[no description available]	low	0	benzoic acids
2-methyl-N-(4-oxo-2-sulfanylidene-3-thiazolidinyl)benzamide	[no description available]	low	0	benzoic acids
N-[3-(2-chlorophenyl)-4-oxo-2-thiazolidinylidene]benzamide	[no description available]	low	0	benzoic acids
N'-[2-[[4-ethyl-5-(2-furanyl)-1,2,4-triazol-3-yl]thio]-1-oxoethyl]-4-methoxybenzohydrazide	[no description available]	low	0	benzoic acids
4-[5-(carboxymethyl)-4-phenyl-2-thiazolyl]benzoic acid	[no description available]	low	0	benzoic acids
4-[4-(2,4-dichlorophenyl)-2-thiazolyl]benzoic acid	[no description available]	low	0	benzoic acids
3-methyl-N-[oxo-[(2,4,6-trimethyl-3-pyridinyl)amino]methyl]benzamide	[no description available]	low	0	benzoic acids
4-methoxy-N-[[(1-oxo-2-phenoxyethyl)hydrazo]-sulfanylidenemethyl]benzamide	[no description available]	low	0	benzoic acids
4-methyl-N-[(1-oxopentylhydrazo)-sulfanylidenemethyl]benzamide	[no description available]	low	0	benzoic acids
N-[[[(2-methylphenyl)-oxomethyl]hydrazo]-sulfanylidenemethyl]benzamide	[no description available]	low	0	benzoic acids
2-methyl-N-[[[oxo-(3,4,5-trimethoxyphenyl)methyl]hydrazo]-sulfanylidenemethyl]benzamide	[no description available]	low	0	benzoic acids
N-[[[(4-methoxyphenyl)-oxomethyl]hydrazo]-sulfanylidenemethyl]-2-furancarboxamide	[no description available]	low	0	benzoic acids
4-methoxy-N-(3-methyl-2-thiazolylidene)benzamide	[no description available]	low	0	benzoic acids
N-[[[oxo(thiophen-2-yl)methyl]hydrazo]-sulfanylidenemethyl]benzamide	[no description available]	low	0	benzoic acids
2-[(2-bromophenyl)methoxy]benzoic acid	[no description available]	low	0	benzoic acids
4-methyl-N-[sulfanylidene-(1,2,4-triazol-4-ylamino)methyl]benzamide	[no description available]	low	0	benzoic acids
3-(difluoromethoxy)-N-(4,5-dihydrothiazol-2-yl)benzamide	[no description available]	low	0	benzoic acids
2-({[2-acetyl-5-(tert-butyl)-3-thienyl]amino}carbonyl)benzoic acid	[no description available]	low	0	benzoic acids
N'-benzoyl-2-(3-pyridinyl)-4-thiazolecarbohydrazide	[no description available]	low	0	benzoic acids
olivetolic acid	[no description available]	low	0	benzoic acids; monocarboxylic acid; polyketide; resorcinols	metabolite
[3-(2-hydroxyphenyl)-5-phenyl-3,4-dihydropyrazol-2-yl]-phenylmethanone	[no description available]	low	0	benzoic acids
4-(1,1,2,3,3,3-hexafluoropropoxy)benzoic acid	[no description available]	low	0	benzoic acids
1-salicylate glucuronide	[no description available]	low	0	benzoic acids; beta-D-glucosiduronic acid	metabolite
4-[[(4-tert-butylphenyl)-oxomethyl]hydrazo]-N-(5-methyl-3-isoxazolyl)-4-oxobutanamide	[no description available]	low	0	benzoic acids
2-[(3-methoxyphenyl)-oxomethyl]imino-3,4-dimethyl-5-thiazolecarboxylic acid ethyl ester	[no description available]	low	0	benzoic acids
2-(6-amino-5-cyano-3-thiophen-2-yl-2,4-dihydropyrano[2,3-c]pyrazol-4-yl)benzoic acid	[no description available]	low	0	benzoic acids; pyranopyrazole
3-[(4-bromophenoxy)methyl]benzohydrazide	[no description available]	low	0	benzoic acids
1-benzoyl-5-hydroxy-5-(4-methylphenyl)-4H-pyrazole-3-carboxylic acid ethyl ester	[no description available]	low	0	benzoic acids
[4-[(4-bromo-3,5-dimethyl-1-pyrazolyl)methyl]phenyl]-[5-hydroxy-3-methyl-5-(trifluoromethyl)-4H-pyrazol-1-yl]methanone	[no description available]	low	0	benzoic acids
3-[(4-methoxyphenoxy)methyl]-N-(4-nitro-1-pyrazolyl)benzamide	[no description available]	low	0	benzoic acids
2-[(2-chlorophenyl)methoxy]-N-(4,5-dihydrothiazol-2-yl)benzamide	[no description available]	low	0	benzoic acids
N-[[(6-methyl-2-pyridinyl)amino]-oxomethyl]benzamide	[no description available]	low	0	benzoic acids
N-[[(3-cyano-6-methyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)amino]-sulfanylidenemethyl]-2-methylbenzamide	[no description available]	low	0	benzoic acids
N-[bis(methylthio)methylideneamino]-4-hydroxybenzamide	[no description available]	low	0	benzoic acids
4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid	[no description available]	low	0	benzoic acids; naphthalenes; retinoid	antineoplastic agent; retinoic acid receptor agonist; teratogenic agent
bay u9773	[no description available]	low	0	benzoic acids; dicarboxylic acid; organic sulfide; polyunsaturated fatty acid; secondary alcohol	leukotriene antagonist
taprostene	[no description available]	low	0	benzoic acids
nifuroxazide	[no description available]	low	0	benzoic acids
3,4,5-trimethoxy-N-[[[oxo-[(1S,2S)-2-phenylcyclopropyl]methyl]hydrazo]-sulfanylidenemethyl]benzamide	[no description available]	low	0	benzoic acids
bay 58-2667	[no description available]	low	0	aromatic ether; benzoic acids; dicarboxylic acid; tertiary amino compound	antihypertensive agent; soluble guanylate cyclase activator; vasodilator agent
nigerloxin	[no description available]	low	0	aromatic ether; benzamides; benzoic acids; phenols; styrenes	antioxidant; Aspergillus metabolite; EC 1.1.1.21 (aldehyde reductase) inhibitor; lipoxygenase inhibitor; radical scavenger
lumacaftor	[no description available]	low	0	aromatic amide; benzodioxoles; benzoic acids; cyclopropanes; organofluorine compound; pyridines	CFTR potentiator; orphan drug
N'-[(2-methoxyphenyl)-oxomethyl]-2-(4-morpholinyl)-4-thiazolecarbohydrazide	[no description available]	low	0	benzoic acids
4-[[[(2S,3S)-10-[[cyclopropyl(oxo)methyl]amino]-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-2-yl]methyl-methylamino]methyl]benzoic acid	[no description available]	low	0	benzoic acids
gsk2879552	[no description available]	low	0	benzenes; benzoic acids; cyclopropanes; monocarboxylic acid; piperidines; secondary amino compound; tertiary amino compound	antineoplastic agent; EC 1.14.99.66 (lysine-specific histone demethylase 1A) inhibitor
4-[[(4-oxo-1,5,6,7-tetrahydrocyclopenta[d]pyrimidin-2-yl)thio]methyl]benzoic acid	[no description available]	low	0	benzoic acids
butoctamide succinate	[no description available]	low	0	dicarboxylic acid monoester; hemisuccinate; secondary carboxamide
cl 387785	[no description available]	low	0	bromobenzenes; quinazolines; secondary carboxamide; ynamide	antineoplastic agent; EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor; epidermal growth factor receptor antagonist
4-(dimethylamino)-n-(7-(hydroxyamino)-7-oxoheptyl)benzamide	[no description available]	low	0	benzamides; hydroxamic acid; secondary carboxamide; tertiary amino compound	antineoplastic agent; apoptosis inducer; EC 3.5.1.98 (histone deacetylase) inhibitor
nemonapride	[no description available]	low	0	benzamides; monochlorobenzenes; monomethoxybenzene; N-alkylpyrrolidine; secondary amino compound; secondary carboxamide; substituted aniline
niclosamide	[no description available]	low	0	benzamides; C-nitro compound; monochlorobenzenes; salicylanilides; secondary carboxamide	anthelminthic drug; anticoronaviral agent; antiparasitic agent; apoptosis inducer; molluscicide; piscicide; STAT3 inhibitor
pd168393	[no description available]	low	0	acrylamides; bromobenzenes; quinazolines; secondary carboxamide; substituted aniline	epidermal growth factor receptor antagonist
pilsicainide	[no description available]	low	0	organic heterobicyclic compound; secondary carboxamide	anti-arrhythmia drug; sodium channel blocker
pj-34	[no description available]	low	0	phenanthridines; secondary carboxamide; tertiary amino compound	angiogenesis inhibitor; anti-inflammatory agent; antiatherosclerotic agent; antineoplastic agent; apoptosis inducer; cardioprotective agent; EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor; neuroprotective agent
opc 12759	[no description available]	low	0	secondary carboxamide
suramin	[no description available]	low	0	naphthalenesulfonic acid; phenylureas; secondary carboxamide	angiogenesis inhibitor; antinematodal drug; antineoplastic agent; apoptosis inhibitor; EC 2.7.11.13 (protein kinase C) inhibitor; GABA antagonist; GABA-gated chloride channel antagonist; purinergic receptor P2 antagonist; ryanodine receptor agonist; trypanocidal drug
2-[[3-(3,4-dimethoxyphenyl)-1-oxoprop-2-enyl]amino]benzoic acid	[no description available]	low	0	amidobenzoic acid; cinnamamides; secondary carboxamide
acedapsone	[no description available]	low	0	acetamides; anilide; secondary carboxamide; sulfone	antimalarial; antimicrobial drug
salicylurate	[no description available]	low	0	N-acylglycine; secondary carboxamide	human xenobiotic metabolite; uremic toxin
monoacetyldapsone	[no description available]	low	0	acetamides; anilide; secondary carboxamide; sulfone
n-methylolacrylamide	[no description available]	low	0	secondary carboxamide
win 18446	[no description available]	low	0	organochlorine compound; secondary carboxamide	EC 1.2.1.3 [aldehyde dehydrogenase (NAD(+))] inhibitor
carboxin	[no description available]	low	0	anilide fungicide; anilide; enamide; organosulfur heterocyclic compound; oxacycle; secondary carboxamide	antifungal agrochemical; EC 1.3.5.1 [succinate dehydrogenase (quinone)] inhibitor
tromantadine	[no description available]	low	0	secondary carboxamide
aureothricin	[no description available]	low	0	dithiolopyrrolone antibiotic; secondary carboxamide	angiogenesis inhibitor; antibacterial agent; bacterial metabolite; EC 2.7.7.6 (RNA polymerase) inhibitor
morphazinamide	[no description available]	low	0	morpholines; pyrazines; secondary carboxamide
amperozide	[no description available]	low	0	diarylmethane; monofluorobenzenes; N-alkylpiperazine; secondary carboxamide; ureas	anxiolytic drug; dopamine uptake inhibitor; geroprotector; second generation antipsychotic; serotonergic antagonist
n-acetyltryptophanamide	[no description available]	low	0	acetamides; L-tryptophan derivative; primary carboxamide; secondary carboxamide
gamma-glutamyltyrosine	[no description available]	low	0	dicarboxylic acid; dipeptide; phenols; primary amino compound; secondary carboxamide	human metabolite
n-acetyldopamine	[no description available]	low	0	acetamides; catechols; N-(fatty acyl)-dopamine; secondary carboxamide	human urinary metabolite; marine metabolite
n-acetylcytidine	[no description available]	low	0	acetamides; cytidines; secondary carboxamide	metabolite
florfenicol	[no description available]	low	0	organochlorine compound; organofluorine compound; secondary alcohol; secondary carboxamide; sulfone	antimicrobial agent
marimastat	[no description available]	low	0	hydroxamic acid; secondary carboxamide	antineoplastic agent; matrix metalloproteinase inhibitor
n-(3-oxohexanoyl)-3-aminodihydro-2(3h)-furanone	[no description available]	low	0	N-acyl homoserine lactone; secondary carboxamide
mosapride	[no description available]	low	0	aromatic ether; benzamides; monochlorobenzenes; monofluorobenzenes; morpholines; secondary carboxamide; substituted aniline; tertiary amino compound
benzyloxycarbonylphenylalanylphenylalanine diazomethyl ketone	[no description available]	low	0	carboxylic ester; diazo compound; L-phenylalanine derivative; secondary carboxamide	cathepsin L (EC 3.4.22.15) inhibitor
yh 439	[no description available]	low	0	aromatic amide; isopropyl ester; secondary carboxamide
cyc 682	[no description available]	low	0	nitrile; nucleoside analogue; secondary carboxamide	antimetabolite; antineoplastic agent; DNA synthesis inhibitor; prodrug
sceptrin	[no description available]	low	0	pyrroles; secondary carboxamide
n(beta)-alanyldopamine	[no description available]	low	0	catechols; primary amino compound; secondary carboxamide
monoacetylcadaverine	[no description available]	low	0	acetamides; N-substituted cadaverine; primary amino compound; secondary carboxamide	human metabolite
N-(1-phenylethyl)acetamide	[no description available]	low	0	acetamides; secondary carboxamide
2,2,2-trifluoro-N-[2-(1H-indol-3-yl)ethyl]acetamide	[no description available]	low	0	indoles; secondary carboxamide; trifluoroacetamide
xv 638	[no description available]	low	0	1,3-thiazoles; benzamides; diazepanone; diol; secondary alcohol; secondary carboxamide; ureas	HIV protease inhibitor
vibriobactin	[no description available]	low	0	1,3-oxazoles; secondary carboxamide	siderophore
tempace	[no description available]	low	0	aminoxyls; piperidinecarboxamide; secondary carboxamide	radiation protective agent; radical scavenger
dimethyloxalylglycine	[no description available]	low	0	glycine derivative; methyl ester; secondary carboxamide	EC 1.14.11.29 (hypoxia-inducible factor-proline dioxygenase) inhibitor; neuroprotective agent
s 1033	[no description available]	low	0	(trifluoromethyl)benzenes; imidazoles; pyridines; pyrimidines; secondary amino compound; secondary carboxamide	anticoronaviral agent; antineoplastic agent; tyrosine kinase inhibitor
3-methyl-2-[[oxo-(4-pentoxyphenyl)methyl]amino]butanoic acid	[no description available]	low	0	secondary carboxamide
cinromide	[no description available]	low	0	cinnamamides; secondary carboxamide
4-[[2-furanyl(oxo)methyl]amino]benzoic acid propan-2-yl ester	[no description available]	low	0	aromatic amide; furans; isopropyl ester; secondary carboxamide
N-(3-carbamoyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-2-pyrazinecarboxamide	[no description available]	low	0	primary carboxamide; pyrazines; secondary carboxamide
2-[[oxo(thiophen-2-yl)methyl]amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylic acid propan-2-yl ester	[no description available]	low	0	aromatic amide; isopropyl ester; secondary carboxamide; thiophenes
N-[1-[(4-chlorophenyl)methyl]-4-pyrazolyl]-2-pyrazinecarboxamide	[no description available]	low	0	pyrazines; secondary carboxamide
4-[[(4-bromo-2-ethyl-3-pyrazolyl)-oxomethyl]amino]benzoic acid propan-2-yl ester	[no description available]	low	0	aromatic amide; isopropyl ester; secondary carboxamide
(2S)-2-[[(2-chlorophenyl)-oxomethyl]amino]-3-methylbutanoic acid (6-nitro-4H-1,3-benzodioxin-8-yl)methyl ester	[no description available]	low	0	secondary carboxamide
N-[(2S)-1-(1H-benzimidazol-2-ylamino)-3-methyl-1-oxobutan-2-yl]-3,5-dimethoxybenzamide	[no description available]	low	0	secondary carboxamide
2-(2,4-dioxo-1H-pyrimidin-6-yl)-N-[2-(4-morpholinyl)ethyl]acetamide	[no description available]	low	0	morpholines; pyrimidone; secondary carboxamide; tertiary amino compound
N-[(4-chlorophenyl)methyl]-2-(2,4-dioxo-1H-pyrimidin-6-yl)acetamide	[no description available]	low	0	monochlorobenzenes; pyrimidone; secondary carboxamide
N-[(2S)-1-(1H-benzimidazol-2-ylamino)-3-methyl-1-oxobutan-2-yl]-3-methylbenzamide	[no description available]	low	0	secondary carboxamide
2,2,2-trifluoro-N-(5-oxo-1-phenyl-4H-pyrazol-3-yl)acetamide	[no description available]	low	0	pyrazoles; secondary carboxamide; trifluoroacetamide
N-(2-anilino-2-oxoethyl)-2-methoxybenzamide	[no description available]	low	0	secondary carboxamide
N-[5-[(2,6-dichlorophenyl)methylthio]-1,3,4-thiadiazol-2-yl]-5-methyl-2-pyrazinecarboxamide	[no description available]	low	0	pyrazines; secondary carboxamide
(2S)-3-methyl-2-[[(3-methylphenyl)-oxomethyl]amino]butanoic acid (4-oxo-2-pyrimido[2,1-b][1,3]benzothiazolyl)methyl ester	[no description available]	low	0	secondary carboxamide
n-(1-oxyl-2,2,6,6-tetramethyl-4-piperidinyl)iodoacetamide	[no description available]	low	0	aminoxyls; organoiodine compound; piperidinecarboxamide; secondary carboxamide	radical scavenger; spin label
ANA-12	[no description available]	low	0	1-benzothiophenes; caprolactams; secondary carboxamide	antidepressant; anxiolytic drug; tropomyosin-related kinase B receptor antagonist
N-([biphenyl]-2-yl)-3-cyclopentylpropanamide	[no description available]	low	0	biphenyls; cyclopentanes; secondary carboxamide
bms 387032	[no description available]	low	0	1,3-oxazoles; 1,3-thiazoles; organic sulfide; piperidinecarboxamide; secondary carboxamide	angiogenesis inhibitor; antineoplastic agent; apoptosis inducer; EC 2.7.11.22 (cyclin-dependent kinase) inhibitor
sr 144528	[no description available]	low	0	bridged compound; monochlorobenzenes; pyrazoles; secondary carboxamide	CB2 receptor antagonist; EC 2.3.1.26 (sterol O-acyltransferase) inhibitor
N-(1,3-benzodioxol-5-ylmethyl)-N-[2-(cyclohexylamino)-2-oxo-1-pyridin-4-ylethyl]-2,2,2-trifluoroacetamide	[no description available]	low	0	benzodioxoles; pyridines; secondary carboxamide; tertiary carboxamide; trifluoroacetamide
N-[2-(cyclohexylamino)-2-oxo-1-thiophen-2-ylethyl]-2,2,2-trifluoro-N-(4-methylphenyl)acetamide	[no description available]	low	0	secondary carboxamide; tertiary carboxamide; thiophenes; trifluoroacetamide
ML162	[no description available]	low	0	monochlorobenzenes; monomethoxybenzene; organochlorine compound; secondary carboxamide; tertiary carboxamide; thiophenes	EC 1.11.1.9 (glutathione peroxidase) inhibitor; ferroptosis inducer
N-[3-(N-(2-chloro-1-oxoethyl)-4-nitroanilino)propyl]-2,2,2-trifluoroacetamide	[no description available]	low	0	C-nitro compound; secondary carboxamide; tertiary carboxamide; trifluoroacetamide
2-[[2-(3,4-dimethoxyanilino)-2-oxoethyl]thio]-3-pyridinecarboxylic acid propan-2-yl ester	[no description available]	low	0	dimethoxybenzene; isopropyl ester; secondary carboxamide
fagaramide	[no description available]	low	0	cinnamamides; secondary carboxamide
arachidonyl dopamine	[no description available]	low	0	catechols; fatty amide; N-(fatty acyl)-dopamine; secondary carboxamide
n-oleoyldopamine	[no description available]	low	0	catechols; fatty amide; N-(fatty acyl)-dopamine; secondary carboxamide	TRPV1 agonist
tranilast	[no description available]	low	0	amidobenzoic acid; cinnamamides; dimethoxybenzene; secondary carboxamide	anti-allergic agent; anti-asthmatic drug; antineoplastic agent; aryl hydrocarbon receptor agonist; calcium channel blocker; hepatoprotective agent; nephroprotective agent
arachidonyl-2-chloroethylamide	[no description available]	low	0	fatty amide; organochlorine compound; secondary carboxamide; synthetic cannabinoid	CB1 receptor agonist; CB2 receptor agonist; neuroprotective agent
l796778	[no description available]	low	0	benzenes; C-nitro compound; L-lysine derivative; L-phenylalanine derivative; methyl ester; oligopeptide; secondary carboxamide; ureas	somatostatin receptor agonist
l803087	[no description available]	low	0	benzenes; fluoroindole; guanidines; L-arginine derivative; methyl ester; phenylindole; secondary carboxamide	somatostatin receptor agonist
n-cinnamoyltyramine	[no description available]	low	0	cinnamamides; phenols; secondary carboxamide	allelochemical; antimicrobial agent; phytoalexin; platelet aggregation inhibitor
ag-490	[no description available]	low	0	catechols; enamide; monocarboxylic acid amide; nitrile; secondary carboxamide	anti-inflammatory agent; antioxidant; apoptosis inducer; EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor; geroprotector; STAT3 inhibitor
4-amylcinnamoylanthranilic acid	[no description available]	low	0	amidobenzoic acid; cinnamamides; secondary carboxamide	EC 3.1.1.4 (phospholipase A2) inhibitor; TRP channel blocker
batimastat	[no description available]	low	0	hydroxamic acid; L-phenylalanine derivative; organic sulfide; secondary carboxamide; thiophenes; triamide	angiogenesis inhibitor; antineoplastic agent; matrix metalloproteinase inhibitor
pipercallosidine	[no description available]	low	0	alkaloid; benzodioxoles; enamide; secondary carboxamide	apoptosis inducer; metabolite; plant metabolite
pederin	[no description available]	low	0	cyclic ketal; diol; oxanes; polyketide; secondary alcohol; secondary carboxamide	antimitotic; antineoplastic agent; bacterial metabolite; vesicant
streptogramin a	[no description available]	low	0	1,3-oxazoles; cyclic ketone; enamide; lactam; macrolide antibiotic; macrolide; pyrroline; secondary alcohol; secondary carboxamide; tertiary carboxamide	antibacterial drug; Mycoplasma genitalium metabolite
cinanserin	[no description available]	low	0	aryl sulfide; cinnamamides; secondary carboxamide; tertiary amino compound	anticoronaviral agent; antiviral agent; EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor
pepstatin	[no description available]	low	0	pentapeptide; secondary carboxamide	bacterial metabolite; EC 3.4.23.* (aspartic endopeptidase) inhibitor
ximelagatran	[no description available]	low	0	amidoxime; azetidines; carboxamide; ethyl ester; hydroxylamines; secondary amino compound; secondary carboxamide; tertiary carboxamide	anticoagulant; EC 3.4.21.5 (thrombin) inhibitor; prodrug; serine protease inhibitor
(6R,7R)-7-[[(2R)-2-carboxy-2-(4-hydroxyphenyl)-1-oxoethyl]amino]-7-methoxy-3-[[(1-methyl-5-tetrazolyl)thio]methyl]-8-oxo-5-oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid	[no description available]	low	0	dicarboxylic acid; secondary carboxamide
DPI2	[no description available]	low	0	benzenes; morpholines; secondary carboxamide; tertiary amino compound; thiazolidinone	ferroptosis inducer
su 1498	[no description available]	low	0	enamide; monocarboxylic acid amide; nitrile; phenols; secondary carboxamide	vascular endothelial growth factor receptor antagonist
n-feruloylserotonin	[no description available]	low	0	aromatic ether; cinnamamides; hydroxyindoles; phenols; secondary carboxamide	plant metabolite
oroidin	[no description available]	low	0	pyrroles; secondary carboxamide	metabolite
ro 42-5892	[no description available]	low	0	cyclopropanes; diol; L-histidine derivative; secondary carboxamide; sulfone	antihypertensive agent; EC 3.4.23.15 (renin) inhibitor; peptidomimetic; vasodilator agent
s 1006	[no description available]	low	0	1,3-thiazoles; carbamate ester; carboxylic acid; cephalosporin; enamide; secondary carboxamide	antibacterial drug
manumycin	[no description available]	low	0	enamide; epoxide; organic heterobicyclic compound; polyketide; secondary carboxamide; tertiary alcohol	antiatherosclerotic agent; antimicrobial agent; antineoplastic agent; apoptosis inducer; bacterial metabolite; EC 1.8.1.9 (thioredoxin reductase) inhibitor; EC 2.5.1.58 (protein farnesyltransferase) inhibitor; marine metabolite
asukamycin	[no description available]	low	0	enamide; epoxide; organic heterobicyclic compound; polyketide; secondary carboxamide; tertiary alcohol	antibacterial agent; antifungal agent; antimicrobial agent; antineoplastic agent; bacterial metabolite
kalimantacin a	[no description available]	low	0	alpha,beta-unsaturated monocarboxylic acid; carbamate ester; fatty acid derivative; secondary carboxamide	antibacterial agent; antimicrobial agent; bacterial metabolite
l 744832	[no description available]	low	0	benzenes; ether; isopropyl ester; secondary carboxamide; sulfone; thiol	antineoplastic agent; EC 2.5.1.58 (protein farnesyltransferase) inhibitor; geroprotector
mocetinostat	[no description available]	low	0	aminopyrimidine; benzamides; pyridines; secondary amino compound; secondary carboxamide; substituted aniline	antineoplastic agent; apoptosis inducer; autophagy inducer; cardioprotective agent; EC 3.5.1.98 (histone deacetylase) inhibitor; hepatotoxic agent
l 779976	[no description available]	low	0	benzimidazoles; indoles; piperidinecarboxamide; primary amino compound; secondary carboxamide	neuroprotective agent; somatostatin receptor agonist
ustiloxin b	[no description available]	low	0	aromatic ether; heterodetic cyclic peptide; macrocycle; phenols; secondary alcohol; secondary carboxamide; sulfoxide	Aspergillus metabolite; microtubule-destabilising agent; mycotoxin
dysidenin	[no description available]	low	0	1,3-thiazoles; organochlorine compound; secondary carboxamide; tertiary carboxamide	animal metabolite; marine metabolite; toxin
avenanthramide b	[no description available]	low	0	amidobenzoic acid; cinnamamides; monohydroxybenzoic acid; monomethoxybenzene; phenols; secondary carboxamide	antineoplastic agent; apoptosis inducer; phytoalexin
azd2858	[no description available]	low	0	aromatic amine; N-methylpiperazine; pyrazines; pyridines; secondary carboxamide; sulfonamide	antineoplastic agent; bone density conservation agent; EC 2.7.11.26 (tau-protein kinase) inhibitor; Wnt signalling activator
bibw 2992	[no description available]	low	0	aromatic ether; enamide; furans; monochlorobenzenes; organofluorine compound; quinazolines; secondary carboxamide; tertiary amino compound	antineoplastic agent; tyrosine kinase inhibitor
betrixaban	[no description available]	low	0	benzamides; guanidines; monochloropyridine; monomethoxybenzene; secondary carboxamide	anticoagulant; EC 3.4.21.6 (coagulation factor Xa) inhibitor
fr 900848	[no description available]	low	0	cyclopropanes; nucleoside analogue; olefinic compound; polyketide; secondary carboxamide	antifungal agent; bacterial metabolite
pha 665752	[no description available]	low	0	dichlorobenzene; enamide; indolones; N-acylpyrrolidine; pyrrolecarboxamide; secondary carboxamide; sulfone; tertiary carboxamide	antineoplastic agent; c-Met tyrosine kinase inhibitor
n-benzylhexadecanamide	[no description available]	low	0	macamide; secondary carboxamide	EC 3.5.1.99 (fatty acid amide hydrolase) inhibitor; neuroprotective agent; plant metabolite
chlorantranilipole	[no description available]	low	0	monochlorobenzenes; organobromine compound; pyrazole insecticide; pyrazoles; pyridines; secondary carboxamide	ryanodine receptor agonist
cenicriviroc	[no description available]	low	0	aromatic ether; benzazocine; diether; imidazoles; secondary carboxamide; sulfoxide	anti-HIV agent; anti-inflammatory agent; antirheumatic drug; chemokine receptor 2 antagonist; chemokine receptor 5 antagonist
at 7519	[no description available]	low	0	dichlorobenzene; piperidines; pyrazoles; secondary carboxamide	antineoplastic agent; EC 2.7.11.22 (cyclin-dependent kinase) inhibitor
azd 1152	[no description available]	low	0	anilide; monoalkyl phosphate; monofluorobenzenes; pyrazoles; quinazolines; secondary amino compound; secondary carboxamide; tertiary amino compound	antineoplastic agent; Aurora kinase inhibitor; prodrug
pf 00299804	[no description available]	low	0	enamide; monochlorobenzenes; monofluorobenzenes; piperidines; quinazolines; secondary amino compound; secondary carboxamide; tertiary amino compound	antineoplastic agent; epidermal growth factor receptor antagonist
MI-63	[no description available]	low	0	azaspiro compound; monochlorobenzenes; monofluorobenzenes; morpholines; oxindoles; pyrrolidines; secondary carboxamide	apoptosis inducer
PF-00835231	[no description available]	low	0	aromatic ether; indolecarboxamide; L-leucine derivative; primary alcohol; pyrrolidin-2-ones; secondary carboxamide	anticoronaviral agent; drug metabolite; EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor
cyantraniliprole	[no description available]	low	0	nitrile; organobromine compound; organochlorine compound; pyrazole insecticide; pyridines; secondary carboxamide	ryanodine receptor agonist
VPC 23019	[no description available]	low	0	aromatic amide; D-serine derivative; organic phosphate; phosphoric ester; secondary carboxamide	sphingosine-1-phosphate receptor 1 antagonist; sphingosine-1-phosphate receptor 3 antagonist
pd 0348292	[no description available]	low	0	monochlorobenzenes; monofluorobenzenes; pyridone; pyrrolidines; secondary carboxamide; ureas	anticoagulant; EC 3.4.21.6 (coagulation factor Xa) inhibitor; serine protease inhibitor
narlaprevir	[no description available]	low	0	azabicyclohexane; cyclopropanes; pyrrolidinecarboxamide; secondary carboxamide; sulfone; tertiary carboxamide; ureas	anticoronaviral agent; antiviral drug; EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor; hepatitis C protease inhibitor
tosedostat	[no description available]	low	0	carboxylic ester; hydroxamic acid; secondary carboxamide
4-chloro-N-[1-[[5-(ethylthio)-1,3,4-thiadiazol-2-yl]amino]-3-methyl-1-oxobutan-2-yl]benzamide	[no description available]	low	0	secondary carboxamide
azd 1152-hqpa	[no description available]	low	0	anilide; monofluorobenzenes; primary alcohol; pyrazoles; quinazolines; secondary amino compound; secondary carboxamide; tertiary amino compound	antineoplastic agent; Aurora kinase inhibitor
(2S)-2-[[[5-[[5-[[(2-methylpropan-2-yl)oxy-oxomethyl]amino]pentylamino]-oxomethyl]-1H-imidazol-4-yl]-oxomethyl]amino]propanoic acid tert-butyl ester	[no description available]	low	0	secondary carboxamide; tert-butyl ester
(2S)-2-[[[5-[[methyl-(phenylmethyl)amino]-oxomethyl]-1H-imidazol-4-yl]-oxomethyl]amino]-6-[[(2-methylpropan-2-yl)oxy-oxomethyl]amino]hexanoic acid tert-butyl ester	[no description available]	low	0	secondary carboxamide; tert-butyl ester; tertiary carboxamide
(2S,3S,4R)-4-cyclopropyl-2-ethoxy-3-(3-hydroxypropyl)-N-prop-2-ynyl-3,4-dihydro-2H-pyran-6-carboxamide	[no description available]	low	0	secondary carboxamide
sid 26681509	[no description available]	low	0	carbohydrazide; L-tryptophan derivative; secondary carboxamide; tert-butyl ester; thioester	antiplasmodial drug; cathepsin L (EC 3.4.22.15) inhibitor
azd 7545	[no description available]	low	0	benzamides; monochlorobenzenes; organofluorine compound; secondary carboxamide; sulfone; tertiary alcohol; tertiary carboxamide	EC 2.7.11.2 - [pyruvate dehydrogenase (acetyl-transferring)] kinase inhibitor; hypoglycemic agent
sm 164	[no description available]	low	0	benzenes; organic heterobicyclic compound; secondary carboxamide; triazoles	antineoplastic agent; apoptosis inducer; radiosensitizing agent
sch772984	[no description available]	low	0	biaryl; indazoles; N-acylpiperazine; N-alkylpyrrolidine; N-arylpiperazine; pyridines; pyrimidines; pyrrolidinecarboxamide; secondary carboxamide; tertiary amino compound; tertiary carboxamide	analgesic; antineoplastic agent; apoptosis inducer; EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor
GRL-0617	[no description available]	low	0	benzamides; naphthalenes; secondary carboxamide; substituted aniline	anticoronaviral agent; protease inhibitor
entrectinib	[no description available]	low	0	benzamides; difluorobenzene; indazoles; N-methylpiperazine; oxanes; secondary amino compound; secondary carboxamide	antibacterial agent; antineoplastic agent; apoptosis inducer; EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor
TAK-580	[no description available]	low	0	1,3-thiazolecarboxamide; aminopyrimidine; chloropyridine; organofluorine compound; pyrimidinecarboxamide; secondary carboxamide	antineoplastic agent; apoptosis inducer; B-Raf inhibitor
cx 5461	[no description available]	low	0	diazepine; naphthyridine derivative; organic heterotetracyclic compound; pyrazines; secondary carboxamide	antineoplastic agent; apoptosis inducer; EC 2.7.7.6 (RNA polymerase) inhibitor
KOM70144	[no description available]	low	0	acetamides; benzamides; naphthalenes; secondary carboxamide	anticoronaviral agent; protease inhibitor
monepantel	[no description available]	low	0	(trifluoromethyl)benzenes; aromatic ether; aryl sulfide; nitrile; secondary carboxamide	anthelminthic drug; nematicide
ulixacaltamide	[no description available]	low	0	benzamides; monochlorobenzenes; monofluorobenzenes; piperidines; secondary carboxamide	non-narcotic analgesic; T-type calcium channel blocker
EG00229	[no description available]	low	0	benzothiadiazole; dicarboxylic acid monoamide; L-arginine derivative; secondary carboxamide; sulfonamide; thiophenes	angiogenesis inhibitor; antineoplastic agent; neuropilin receptor antagonist
tak-632	[no description available]	low	0	(trifluoromethyl)benzenes; aromatic ether; benzothiazoles; cyclopropylcarboxamide; monofluorobenzenes; nitrile; secondary carboxamide	antineoplastic agent; apoptosis inducer; B-Raf inhibitor; EC 2.7.11.26 (tau-protein kinase) inhibitor; necroptosis inhibitor
lgk974	[no description available]	low	0	bipyridines; pyrazines; pyridines; secondary carboxamide	Wnt signalling inhibitor
gsk-5498a	[no description available]	low	0	(trifluoromethyl)benzenes; difluorobenzene; pyrazoles; secondary carboxamide	calcium channel blocker
2-methoxy-N-[3-[4-[3-methyl-4-[(6-methyl-3-pyridinyl)oxy]anilino]-6-quinazolinyl]prop-2-enyl]acetamide	[no description available]	low	0	aromatic ether; methylpyridines; olefinic compound; quinazolines; secondary amino compound; secondary carboxamide; toluenes
raltegravir	[no description available]	low	0	1,2,4-oxadiazole; dicarboxylic acid amide; hydroxypyrimidine; monofluorobenzenes; pyrimidone; secondary carboxamide	antiviral drug; HIV-1 integrase inhibitor
lfm a13	[no description available]	low	0	aromatic amide; dibromobenzene; enamide; enol; nitrile; secondary carboxamide	antineoplastic agent; apoptosis inducer; EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor; EC 2.7.11.21 (polo kinase) inhibitor; geroprotector; platelet aggregation inhibitor
teriflunomide	[no description available]	low	0	(trifluoromethyl)benzenes; aromatic amide; enamide; enol; nitrile; secondary carboxamide	drug metabolite; EC 1.3.98.1 [dihydroorotate oxidase (fumarate)] inhibitor; hepatotoxic agent; non-steroidal anti-inflammatory drug; tyrosine kinase inhibitor
gsk1265744	[no description available]	low	0	difluorobenzene; monocarboxylic acid amide; organic heterotricyclic compound; secondary carboxamide	HIV-1 integrase inhibitor
dolutegravir	[no description available]	low	0	difluorobenzene; monocarboxylic acid amide; organic heterotricyclic compound; secondary carboxamide	HIV-1 integrase inhibitor
LimKi 3	[no description available]	low	0	1,3-thiazoles; dichlorobenzene; organofluorine compound; pyrazoles; secondary carboxamide	LIM kinase inhibitor
MK-8353	[no description available]	low	0	aromatic ether; dihydropyridine; indazoles; methyl sulfide; N-alkylpyrrolidine; pyridines; pyrrolidinecarboxamide; secondary carboxamide; tertiary carboxamide; triazoles	antineoplastic agent; apoptosis inducer; EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor
acp-196	[no description available]	low	0	aromatic amine; benzamides; imidazopyrazine; pyridines; pyrrolidinecarboxamide; secondary carboxamide; tertiary carboxamide; ynone	antineoplastic agent; apoptosis inducer; EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor
gsk343	[no description available]	low	0	aminopyridine; indazoles; N-alkylpiperazine; N-arylpiperazine; pyridone; secondary carboxamide	antineoplastic agent; apoptosis inducer; EC 2.1.1.43 (enhancer of zeste homolog 2) inhibitor
osimertinib	[no description available]	low	0	acrylamides; aminopyrimidine; biaryl; indoles; monomethoxybenzene; secondary amino compound; secondary carboxamide; substituted aniline; tertiary amino compound	antineoplastic agent; epidermal growth factor receptor antagonist
ivosidenib	[no description available]	low	0	cyanopyridine; monochlorobenzenes; organofluorine compound; pyrrolidin-2-ones; secondary carboxamide; tertiary carboxamide	antineoplastic agent; EC 1.1.1.42 (isocitrate dehydrogenase) inhibitor
atogepant	[no description available]	low	0	azaspiro compound; organic heterotetracyclic compound; piperidones; secondary carboxamide; trifluorobenzene	calcitonin gene-related peptide receptor antagonist
DDR1-IN-1	[no description available]	low	0	(trifluoromethyl)benzenes; aromatic ether; benzamides; N-alkylpiperazine; oxindoles; secondary carboxamide	EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor
bictegravir	[no description available]	low	0	monocarboxylic acid amide; organic heterotetracyclic compound; secondary carboxamide; trifluorobenzene	HIV-1 integrase inhibitor
THZ531	[no description available]	low	0	aminopyrimidine; enamide; indoles; N-acylpiperidine; organochlorine compound; secondary amino compound; secondary carboxamide	antineoplastic agent; apoptosis inducer; EC 2.7.11.22 (cyclin-dependent kinase) inhibitor
AZ3451	[no description available]	low	0	benzimidazoles; benzodioxoles; nitrile; organobromine compound; secondary carboxamide	anti-inflammatory agent; autophagy inducer; PAR2 negative allosteric modulator
MMP-9-IN-1	[no description available]	low	0	aromatic compound; organic sulfide; organofluorine compound; pyrimidone; secondary carboxamide	antineoplastic agent; EC 3.4.24.35 (gelatinase B) inhibitor
althiomycin	[no description available]	low	0	1,3-thiazoles; aldoxime; ether; gamma-lactam; pentapeptide; peptide antibiotic; primary alcohol; pyrroline; secondary carboxamide; tertiary carboxamide	antibacterial agent; bacterial metabolite; protein synthesis inhibitor
colibactin	[no description available]	low	0	1,3-thiazoles; azaspiro compound; polyketide; pyrroline; secondary carboxamide	alkylating agent; carcinogenic agent; Escherichia coli metabolite; genotoxin
N-[(2S)-3-cyclohexyl-1-oxo-1-({(2S)-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}amino)propan-2-yl]-1H-indole-2-carboxamide	[no description available]	low	0	aldehyde; indolecarboxamide; oligopeptide; pyrrolidin-2-ones; secondary carboxamide	anticoronaviral agent; EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor
3-fluoro-Nalpha-(1H-indol-2-ylcarbonyl)-N-{(2S)-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-phenylalaninamide	[no description available]	low	0	aldehyde; indolecarboxamide; monofluorobenzenes; oligopeptide; pyrrolidin-2-ones; secondary carboxamide	anticoronaviral agent; EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor
PF-07304814	[no description available]	low	0	aromatic ether; indolecarboxamide; L-leucine derivative; phosphate monoester; pyrrolidin-2-ones; secondary carboxamide	anticoronaviral agent; EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor; prodrug
nirmatrelvir	[no description available]	low	0	azabicyclohexane; nitrile; organofluorine compound; pyrrolidin-2-ones; pyrrolidinecarboxamide; secondary carboxamide; tertiary carboxamide	anticoronaviral agent; EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor

Condition	Relationship Strength	Studies
Congenital Zika Syndrome	low	1
Congenital Zika Virus Infection	low	1
Disease Models, Animal	low	1
Fever, Zika	low	1
Malaria, Falciparum	low	1
Plasmodium falciparum Malaria	low	1
Zika Fever	low	1
Zika Virus Disease	low	1
Zika Virus Infection	low	1
ZikV Infection	low	1

bms 195614

Description

Cross-References

Synonyms (31)

Roles (1)

Drug Classes (3)

Protein Targets (9)

Potency Measurements

Inhibition Measurements

Biological Processes (115)

Molecular Functions (42)

Ceullar Components (30)

Bioassays (34)

Research

Studies (9)

Study Types

Research Highlights

Bioavailability (1)

Article	Year
A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Molecular pharmacology, Volume: 96, Issue: 5	2019
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]