| Assay ID | Title | Year | Journal | Article |
|---|
| AID748293 | Inhibition of spermatogenesis in CD1 mouse assessed as asynchronization of spermatogenic cell association at 10 mg/kg, po for 7 days measured after 1 month by bright-field microscopic analysis | 2013 | ACS medicinal chemistry letters, May-09, Volume: 4, Issue:5
| Pharmacological activity of retinoic acid receptor alpha-selective antagonists |
| AID748296 | Inhibition of spermatogenesis in CD1 mouse assessed as change in sperm release at stage 9 into lumen in testes at 2 to 10 mg/kg, po for 7 days measured after 1 month by bright-field microscopic analysis relative to control | 2013 | ACS medicinal chemistry letters, May-09, Volume: 4, Issue:5
| Pharmacological activity of retinoic acid receptor alpha-selective antagonists |
| AID748289 | Toxicity in CD1 mouse assessed as change in testosterone levels at 2 to 10 mg/kg, po for 7 days by enzyme immunoassay relative to control | 2013 | ACS medicinal chemistry letters, May-09, Volume: 4, Issue:5
| Pharmacological activity of retinoic acid receptor alpha-selective antagonists |
| AID748292 | Inhibition of spermatogenesis in CD1 mouse assessed as change in morphology of caudal epididymides at 10 mg/kg, po for 7 days measured after 1 month by bright-field microscopic analysis | 2013 | ACS medicinal chemistry letters, May-09, Volume: 4, Issue:5
| Pharmacological activity of retinoic acid receptor alpha-selective antagonists |
| AID748291 | Inhibition of spermatogenesis in CD1 mouse assessed as change in motility of epididymal sperm at 10 mg/kg, po for 7 days measured after 1 month by bright-field microscopic analysis | 2013 | ACS medicinal chemistry letters, May-09, Volume: 4, Issue:5
| Pharmacological activity of retinoic acid receptor alpha-selective antagonists |
| AID748298 | Antagonist activity at human RARalpha expressed in human HeLa cells assessed as inhibition of ATRA-induced RARE-chloramphenicol acetyltransferase reporter gene expression after 24 hrs by transactivation competition assay | 2013 | ACS medicinal chemistry letters, May-09, Volume: 4, Issue:5
| Pharmacological activity of retinoic acid receptor alpha-selective antagonists |
| AID748299 | Antagonist activity at human RARalpha expressed in human HeLa cells assessed as inhibition of ATRA-induced RARE transactivation after 24 hrs by chloramphenicol acetyltransferase reporter gene assay | 2013 | ACS medicinal chemistry letters, May-09, Volume: 4, Issue:5
| Pharmacological activity of retinoic acid receptor alpha-selective antagonists |
| AID748294 | Inhibition of spermatogenesis in CD1 mouse assessed as presence of vacuolar-like spaces at 10 mg/kg, po for 7 days measured after 1 month by bright-field microscopic analysis | 2013 | ACS medicinal chemistry letters, May-09, Volume: 4, Issue:5
| Pharmacological activity of retinoic acid receptor alpha-selective antagonists |
| AID748297 | Inhibition of spermatogenesis in CD1 mouse assessed as change in alignment of step 16 spermatids at lumen in stage 8 tubules in testes at 2 to 10 mg/kg, po for 7 days measured after 1 month by bright-field microscopic analysis relative to control | 2013 | ACS medicinal chemistry letters, May-09, Volume: 4, Issue:5
| Pharmacological activity of retinoic acid receptor alpha-selective antagonists |
| AID748295 | Toxicity in CD1 mouse assessed as change in testicular weight at 2 to 10 mg/kg, po for 7 days relative to control | 2013 | ACS medicinal chemistry letters, May-09, Volume: 4, Issue:5
| Pharmacological activity of retinoic acid receptor alpha-selective antagonists |
| AID748290 | Toxicity in CD1 mouse assessed as change in body weight at 2 to 10 mg/kg, po | 2013 | ACS medicinal chemistry letters, May-09, Volume: 4, Issue:5
| Pharmacological activity of retinoic acid receptor alpha-selective antagonists |
| AID1347161 | Confirmatory screen NINDS Rhodamine qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1346986 | P-glycoprotein substrates identified in KB-3-1 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5
| A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
| AID1347164 | 384 well plate NINDS Rhodamine confirmatory qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1347160 | Primary screen NINDS Rhodamine qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1347158 | ZIKV-mCherry secondary qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1347163 | 384 well plate NINDS AMC confirmatory qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1296008 | Cytotoxic Profiling of Annotated Libraries Using Quantitative High-Throughput Screening | 2020 | SLAS discovery : advancing life sciences R & D, 01, Volume: 25, Issue:1
| Cytotoxic Profiling of Annotated and Diverse Chemical Libraries Using Quantitative High-Throughput Screening. |
| AID1347167 | Vero cells viability qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1346987 | P-glycoprotein substrates identified in KB-8-5-11 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5
| A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
| AID1347168 | HepG2 cells viability qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1347153 | Confirmatory screen GU AMC qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1347156 | DAPI mCherry counterscreen qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1347169 | Tertiary RLuc qRT-PCR qHTS assay for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1347157 | Confirmatory screen GU Rhodamine qHTS for Zika virus inhibitors qHTS | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1347159 | Primary screen GU Rhodamine qHTS for Zika virus inhibitors: Unlinked NS2B-NS3 protease assay | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1347152 | Confirmatory screen NINDS AMC qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1347149 | Furin counterscreen qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1799455 | Competitive Assay from Article 10.1016/S1074-5521(99)80084-2: \\Structural basis for engineering of retinoic acid receptor isotype-selective agonists and antagonists.\\ | 1999 | Chemistry & biology, Aug, Volume: 6, Issue:8
| Structural basis for engineering of retinoic acid receptor isotype-selective agonists and antagonists. |
| AID1794808 | Fluorescence-based screening to identify small molecule inhibitors of Plasmodium falciparum apicoplast DNA polymerase (Pf-apPOL). | 2014 | Journal of biomolecular screening, Jul, Volume: 19, Issue:6
| A High-Throughput Assay to Identify Inhibitors of the Apicoplast DNA Polymerase from Plasmodium falciparum. |
| AID1794808 | Fluorescence-based screening to identify small molecule inhibitors of Plasmodium falciparum apicoplast DNA polymerase (Pf-apPOL). | | | |
| AID1346740 | Human Retinoic acid receptor-alpha (1B. Retinoic acid receptors) | 1999 | Chemistry & biology, Aug, Volume: 6, Issue:8
| Structural basis for engineering of retinoic acid receptor isotype-selective agonists and antagonists. |
| AID1346740 | Human Retinoic acid receptor-alpha (1B. Retinoic acid receptors) | 2000 | Molecular cell, Feb, Volume: 5, Issue:2
| Crystal structure of a heterodimeric complex of RAR and RXR ligand-binding domains. |
| AID1346740 | Human Retinoic acid receptor-alpha (1B. Retinoic acid receptors) | 2002 | Nature, Jan-10, Volume: 415, Issue:6868
| Co-regulator recruitment and the mechanism of retinoic acid receptor synergy. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |