| Assay ID | Title | Year | Journal | Article |
|---|
| AID1604541 | Displacement of [3H]-flumazenil from human GABAA alpha5beta3gamma2 expressed in Ltk cells | | | |
| AID1604539 | Displacement of [3H]-flumazenil from human GABAA alpha2beta3gamma2 expressed in Ltk cells | | | |
| AID1604540 | Displacement of [3H]-flumazenil from human GABAA alpha3beta3gamma2 expressed in Ltk cells | | | |
| AID1553916 | Displacement of [3H]Ro-15-1788 from human GABA alpha2/beta2/gamma2 receptor expressed in HEK cell membranes measured after 2 hrs by topcount method | 2019 | Journal of medicinal chemistry, 06-27, Volume: 62, Issue:12
| Design and Identification of a Novel, Functionally Subtype Selective GABA |
| AID1604544 | Positive allosteric modulation of recombinant human GABAA alpha3beta3gamma2 expressed in Ltk cells assessed as chlordiazepoxide-induced current response by whole cell patch clamp method relative to chlordiazepoxide | | | |
| AID1604538 | Displacement of [3H]-flumazenil from human GABAA alpha1beta3gamma2 expressed in Ltk cells | | | |
| AID1553918 | Positive allosteric modulation of human GABAA alpha1/beta3/gamma2 expressed in HEK293 cells assessed as increase in GABA-stimulated chloride current response at 100 times Ki measured after 15 secs by QPatch electrophysiology method relative to GABA | 2019 | Journal of medicinal chemistry, 06-27, Volume: 62, Issue:12
| Design and Identification of a Novel, Functionally Subtype Selective GABA |
| AID1604568 | In vivo receptor occupancy at GABAA receptor in po dosed Sprague-Dawley rat assessed as brain concentration causing 50% reduction in [3H]-flumazenil receptor labeling by scintillation counting method | | | |
| AID1553919 | Positive allosteric modulation of human GABAA alpha2/beta2/gamma2 expressed in HEK293 cells assessed as increase in GABA-stimulated chloride current response at 100 times Ki measured after 15 secs by QPatch electrophysiology method relative to GABA | 2019 | Journal of medicinal chemistry, 06-27, Volume: 62, Issue:12
| Design and Identification of a Novel, Functionally Subtype Selective GABA |
| AID1604545 | Positive allosteric modulation of recombinant human GABAA alpha5beta3gamma2 expressed in Ltk cells assessed as chlordiazepoxide-induced current response by whole cell patch clamp method relative to chlordiazepoxide | | | |
| AID1604543 | Positive allosteric modulation of recombinant human GABAA alpha2beta3gamma2 expressed in Ltk cells assessed as chlordiazepoxide-induced current response by whole cell patch clamp method relative to chlordiazepoxide | | | |
| AID1604542 | Positive allosteric modulation of recombinant human GABAA alpha1beta3gamma2 expressed in Ltk cells assessed as chlordiazepoxide-induced current response by whole cell patch clamp method relative to chlordiazepoxide | | | |
| AID1296008 | Cytotoxic Profiling of Annotated Libraries Using Quantitative High-Throughput Screening | 2020 | SLAS discovery : advancing life sciences R & D, 01, Volume: 25, Issue:1
| Cytotoxic Profiling of Annotated and Diverse Chemical Libraries Using Quantitative High-Throughput Screening. |
| AID1347159 | Primary screen GU Rhodamine qHTS for Zika virus inhibitors: Unlinked NS2B-NS3 protease assay | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1346986 | P-glycoprotein substrates identified in KB-3-1 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5
| A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
| AID1346987 | P-glycoprotein substrates identified in KB-8-5-11 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5
| A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
| AID1347160 | Primary screen NINDS Rhodamine qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |