| Assay ID | Title | Year | Journal | Article |
|---|
| AID1863876 | Inhibition of MMP-3 (unknown origin) | 2022 | Journal of medicinal chemistry, 08-25, Volume: 65, Issue:16
| Selective Inhibitors of Medium-Size S1' Pocket Matrix Metalloproteinases: A Stepping Stone of Future Drug Discovery. |
| AID675789 | Inhibition of MMP8 using (7-methoxycoumarin-4-yl)acetyl-Pro-Leu-Gly-Leu-(3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl)Ala-Arg-NH2 as substrate incubated for 30 mins prior to substrate addition measured for 10 mins by fluorometry | 2012 | Journal of medicinal chemistry, May-24, Volume: 55, Issue:10
| A new class of highly potent matrix metalloproteinase inhibitors based on triazole-substituted hydroxamates: (radio)synthesis and in vitro and first in vivo evaluation. |
| AID107522 | Inhibition activity against recombinant human stromelysin (Matrix metalloprotease-3) | 1997 | Journal of medicinal chemistry, Aug-01, Volume: 40, Issue:16
| Discovery of CGS 27023A, a non-peptidic, potent, and orally active stromelysin inhibitor that blocks cartilage degradation in rabbits. |
| AID1863875 | Inhibition of MMP-2 (unknown origin) | 2022 | Journal of medicinal chemistry, 08-25, Volume: 65, Issue:16
| Selective Inhibitors of Medium-Size S1' Pocket Matrix Metalloproteinases: A Stepping Stone of Future Drug Discovery. |
| AID1863874 | Inhibition of MMP-1 (unknown origin) | 2022 | Journal of medicinal chemistry, 08-25, Volume: 65, Issue:16
| Selective Inhibitors of Medium-Size S1' Pocket Matrix Metalloproteinases: A Stepping Stone of Future Drug Discovery. |
| AID1863879 | Inhibition of MMP-9 (unknown origin) | 2022 | Journal of medicinal chemistry, 08-25, Volume: 65, Issue:16
| Selective Inhibitors of Medium-Size S1' Pocket Matrix Metalloproteinases: A Stepping Stone of Future Drug Discovery. |
| AID1231564 | Inhibition of human active MMP9 using (7-methoxycoumarin-4-yl) acetyl pro-Leu-Gly-Leu-[3-(2,4-dinitrophenyl)-L-2,3-diamino-propionyl]-Ala-Arg-NH2 fluorogenic substrate assessed as fluorescent product release | 2015 | Bioorganic & medicinal chemistry, Jul-01, Volume: 23, Issue:13
| New matrix metalloproteinase inhibitors based on γ-fluorinated α-aminocarboxylic and α-aminohydroxamic acids. |
| AID769887 | Inhibition of MMP-8 (unknown origin) | 2013 | Journal of medicinal chemistry, Sep-12, Volume: 56, Issue:17
| Inverse 1,2,3-triazole-1-yl-ethyl substituted hydroxamates as highly potent matrix metalloproteinase inhibitors: (radio)synthesis, in vitro and first in vivo evaluation. |
| AID106636 | Inhibitory activity against mouse macrophage metalloelastase (MME) using [3H]elastin as a substrate | 1998 | Bioorganic & medicinal chemistry letters, Apr-21, Volume: 8, Issue:8
| Sulfonamide-based hydroxamic acids as potent inhibitors of mouse macrophage metalloelastase. |
| AID1863878 | Inhibition of MMP-8 (unknown origin) | 2022 | Journal of medicinal chemistry, 08-25, Volume: 65, Issue:16
| Selective Inhibitors of Medium-Size S1' Pocket Matrix Metalloproteinases: A Stepping Stone of Future Drug Discovery. |
| AID1863881 | Inhibition of MMP-13 (unknown origin) | 2022 | Journal of medicinal chemistry, 08-25, Volume: 65, Issue:16
| Selective Inhibitors of Medium-Size S1' Pocket Matrix Metalloproteinases: A Stepping Stone of Future Drug Discovery. |
| AID769889 | Inhibition of MMP-2 (unknown origin) | 2013 | Journal of medicinal chemistry, Sep-12, Volume: 56, Issue:17
| Inverse 1,2,3-triazole-1-yl-ethyl substituted hydroxamates as highly potent matrix metalloproteinase inhibitors: (radio)synthesis, in vitro and first in vivo evaluation. |
| AID675790 | Inhibition of MMP9 using (7-methoxycoumarin-4-yl)acetyl-Pro-Leu-Gly-Leu-(3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl)Ala-Arg-NH2 as substrate incubated for 30 mins prior to substrate addition measured for 10 mins by fluorometry | 2012 | Journal of medicinal chemistry, May-24, Volume: 55, Issue:10
| A new class of highly potent matrix metalloproteinase inhibitors based on triazole-substituted hydroxamates: (radio)synthesis and in vitro and first in vivo evaluation. |
| AID675793 | Inhibition of MMP2 using (7-methoxycoumarin-4-yl)acetyl-Pro-Leu-Gly-Leu-(3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl)Ala-Arg-NH2 as substrate incubated for 30 mins prior to substrate addition measured for 10 mins by fluorometry | 2012 | Journal of medicinal chemistry, May-24, Volume: 55, Issue:10
| A new class of highly potent matrix metalloproteinase inhibitors based on triazole-substituted hydroxamates: (radio)synthesis and in vitro and first in vivo evaluation. |
| AID769888 | Inhibition of MMP-9 (unknown origin) | 2013 | Journal of medicinal chemistry, Sep-12, Volume: 56, Issue:17
| Inverse 1,2,3-triazole-1-yl-ethyl substituted hydroxamates as highly potent matrix metalloproteinase inhibitors: (radio)synthesis, in vitro and first in vivo evaluation. |
| AID1231563 | Inhibition of human active MMP2 using (7-methoxycoumarin-4-yl) acetyl pro-Leu-Gly-Leu-[3-(2,4-dinitrophenyl)-L-2,3-diamino-propionyl]-Ala-Arg-NH2 fluorogenic substrate assessed as fluorescent product release | 2015 | Bioorganic & medicinal chemistry, Jul-01, Volume: 23, Issue:13
| New matrix metalloproteinase inhibitors based on γ-fluorinated α-aminocarboxylic and α-aminohydroxamic acids. |
| AID1863880 | Inhibition of MMP-12 (unknown origin) | 2022 | Journal of medicinal chemistry, 08-25, Volume: 65, Issue:16
| Selective Inhibitors of Medium-Size S1' Pocket Matrix Metalloproteinases: A Stepping Stone of Future Drug Discovery. |
| AID1796992 | Enzyme Inhibition Assay from Article 10.1021/jm960871c: \\Discovery of CGS 27023A, a non-peptidic, potent, and orally active stromelysin inhibitor that blocks cartilage degradation in rabbits.\\ | 1997 | Journal of medicinal chemistry, Aug-01, Volume: 40, Issue:16
| Discovery of CGS 27023A, a non-peptidic, potent, and orally active stromelysin inhibitor that blocks cartilage degradation in rabbits. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |