Assay ID | Title | Year | Journal | Article |
AID57846 | Cardioselectivity expressed as change in blood pressure for 50% increase in right ventricular contractile force in dogs | 1981 | Journal of medicinal chemistry, Jul, Volume: 24, Issue:7
| N-Aralkyl substitution of 2-amino-5,6- and -6,7-dihydroxy-1,2,3,4-tetrahydronaphthalenes. 1. Cardiac and pressor/depressor activities. |
AID1136162 | Agonist activity at Wistar rat brain cholinergic transporter assessed as tritium efflux by measuring [3H]choline release at 2 uM after 20 to 30 mins by liquid scintillation counting analysis relative to control | 1978 | Journal of medicinal chemistry, Aug, Volume: 21, Issue:8
| Facile syntheses of potent dopaminergic argonists and their effect on neurotransmitter release. |
AID58657 | Ionotropic selectivity expressed as change in heart rate for 100 percent increase in right ventricular contractile force in dogs; CF(100) levels not obtained | 1981 | Journal of medicinal chemistry, Jul, Volume: 24, Issue:7
| N-Aralkyl substitution of 2-amino-5,6- and -6,7-dihydroxy-1,2,3,4-tetrahydronaphthalenes. 1. Cardiac and pressor/depressor activities. |
AID1136159 | Agonist activity at Wistar rat cortex dopamine transporter assessed as tritium efflux by measuring [3H]noradrenaline release at 2 uM after 20 mins by liquid scintillation counting analysis relative to total tissue content | 1978 | Journal of medicinal chemistry, Aug, Volume: 21, Issue:8
| Facile syntheses of potent dopaminergic argonists and their effect on neurotransmitter release. |
AID60583 | Inotropic potency expressed as 100 percent increase in right ventricular contractile force in dogs; CF(100) levels not obtained; CF(100) levels not obtained | 1981 | Journal of medicinal chemistry, Jul, Volume: 24, Issue:7
| N-Aralkyl substitution of 2-amino-5,6- and -6,7-dihydroxy-1,2,3,4-tetrahydronaphthalenes. 1. Cardiac and pressor/depressor activities. |
AID73725 | Effective concentration for increasing potency force in guinea pig isolated left atria | 1981 | Journal of medicinal chemistry, Jul, Volume: 24, Issue:7
| N-Aralkyl substitution of 2-amino-5,6- and -6,7-dihydroxy-1,2,3,4-tetrahydronaphthalenes. 1. Cardiac and pressor/depressor activities. |
AID60584 | Inotropic potency expressed as 50 percent increase in right ventricular contractile force in dogs | 1981 | Journal of medicinal chemistry, Jul, Volume: 24, Issue:7
| N-Aralkyl substitution of 2-amino-5,6- and -6,7-dihydroxy-1,2,3,4-tetrahydronaphthalenes. 1. Cardiac and pressor/depressor activities. |
AID1136161 | Agonist activity at Wistar rat brain GABA transporter assessed as tritium efflux by measuring [3H]GABA release at 2 uM after 20 to 30 mins by liquid scintillation counting analysis relative to control | 1978 | Journal of medicinal chemistry, Aug, Volume: 21, Issue:8
| Facile syntheses of potent dopaminergic argonists and their effect on neurotransmitter release. |
AID73727 | Effective concentration for increasing potency rate in guinea pig isolated right atria | 1981 | Journal of medicinal chemistry, Jul, Volume: 24, Issue:7
| N-Aralkyl substitution of 2-amino-5,6- and -6,7-dihydroxy-1,2,3,4-tetrahydronaphthalenes. 1. Cardiac and pressor/depressor activities. |
AID58658 | Ionotropic selectivity expressed as change in heart rate for 50 percent increase in right ventricular contractile force in dogs | 1981 | Journal of medicinal chemistry, Jul, Volume: 24, Issue:7
| N-Aralkyl substitution of 2-amino-5,6- and -6,7-dihydroxy-1,2,3,4-tetrahydronaphthalenes. 1. Cardiac and pressor/depressor activities. |
AID57845 | Cardioselectivity expressed as change in blood pressure for 100% increase in right ventricular contractile force in dogs; CF(100) levels not obtained | 1981 | Journal of medicinal chemistry, Jul, Volume: 24, Issue:7
| N-Aralkyl substitution of 2-amino-5,6- and -6,7-dihydroxy-1,2,3,4-tetrahydronaphthalenes. 1. Cardiac and pressor/depressor activities. |
AID25622 | Evaluated for the pKa value. | 1982 | Journal of medicinal chemistry, Jun, Volume: 25, Issue:6
| Synthesis of 2-(alkylamino)-5,6- and -6,7-dihydroxy-3,4-dihydroquinazolines and evaluation as potential dopamine agonists. |
AID1136160 | Agonist activity at Wistar rat brain serotonin transporter assessed as tritium efflux by measuring [3H]serotonin release at 2 uM after 20 to 30 mins by liquid scintillation counting analysis relative to control | 1978 | Journal of medicinal chemistry, Aug, Volume: 21, Issue:8
| Facile syntheses of potent dopaminergic argonists and their effect on neurotransmitter release. |
AID64453 | Inhibition of binding of [3H]spiroperidol to Dopamine receptor D2 in rat striatal membranes | 2001 | Bioorganic & medicinal chemistry letters, Apr-09, Volume: 11, Issue:7
| Cis- and trans-N-benzyl-octahydrobenzo[g]quinolines. Adrenergic and dopaminergic activity studies. |
AID76919 | Compound was tested for or relative intrinsic activity in guinea pig isolated atrium left atria | 1981 | Journal of medicinal chemistry, Jul, Volume: 24, Issue:7
| N-Aralkyl substitution of 2-amino-5,6- and -6,7-dihydroxy-1,2,3,4-tetrahydronaphthalenes. 1. Cardiac and pressor/depressor activities. |
AID63119 | Evaluated for the percentage vasodilation in the renal artery produced by 3000 nmol administered intra-arterially; NA is No Antagonistic activity | 1982 | Journal of medicinal chemistry, Jun, Volume: 25, Issue:6
| Synthesis of 2-(alkylamino)-5,6- and -6,7-dihydroxy-3,4-dihydroquinazolines and evaluation as potential dopamine agonists. |
AID1136158 | Agonist activity at Wistar rat striatum dopamine transporter assessed as tritium efflux by measuring [3H]dopamine release at 2 uM after 20 mins by liquid scintillation counting analysis relative to total tissue content | 1978 | Journal of medicinal chemistry, Aug, Volume: 21, Issue:8
| Facile syntheses of potent dopaminergic argonists and their effect on neurotransmitter release. |
AID227265 | Percentage increase in contractile force was determined by the effect of DMI (desmethylimipramine, 1 mg/kg, iv) at 200 ug/kg | 1981 | Journal of medicinal chemistry, Jul, Volume: 24, Issue:7
| N-Aralkyl substitution of 2-amino-5,6- and -6,7-dihydroxy-1,2,3,4-tetrahydronaphthalenes. 1. Cardiac and pressor/depressor activities. |
AID76920 | Compound was tested for relative intrinsic activity in guinea pig isolated atrium right atria | 1981 | Journal of medicinal chemistry, Jul, Volume: 24, Issue:7
| N-Aralkyl substitution of 2-amino-5,6- and -6,7-dihydroxy-1,2,3,4-tetrahydronaphthalenes. 1. Cardiac and pressor/depressor activities. |
AID1803082 | CA Activity Assay from Article 10.3109/14756366.2011.591290: \\Effects of dopaminergic compounds on carbonic anhydrase isozymes I, II, and VI.\\ | 2012 | Journal of enzyme inhibition and medicinal chemistry, Jun, Volume: 27, Issue:3
| Effects of dopaminergic compounds on carbonic anhydrase isozymes I, II, and VI. |
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |