Page last updated: 2024-11-12
6-methoxydihydrosanguinarine
Description
6-methoxydihydrosanguinarine: from Corydalis tashiroi (Fumariaceae); structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
| Flora | Rank | Flora Definition | Family | Family Definition |
|---|
| Corydalis | genus | A plant genus of the family FUMARIACEAE (classified by some in PAPAVERACEAE) that contains isoquinoline alkaloids.[MeSH] | Papaveraceae | The poppy plant family of the order Papaverales, subclass Magnoliidae, class Magnoliopsida. These have bisexual, regular, cup-shaped flowers with one superior pistil and many stamens; 2 or 3 conspicuous, separate sepals and a number of separate petals. The fruit is a capsule. Leaves are usually deeply cut or divided into leaflets.[MeSH] |
Cross-References
Synonyms (13)
| Synonym |
|---|
| bdbm50286635 |
| chembl4171637 , |
| 72401-54-8 |
| 6-methoxydihydrosanguinarine |
| AKOS030524962 |
| [1,3]benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridine, 13,14-dihydro-14-methoxy-13-methyl- |
| (-)-14-methoxy-13-methyl-13,14-dihydro-[1,3]dioxolo[4',5':4,5]benzo[1,2-c][1,3]dioxolo[4,5-i]phenanthridine |
| 6-methoxydihydrosanguinarine72401-54-8 |
| MS-25777 |
| 23-methoxy-24-methyl-5,7,18,20-tetraoxa-24-azahexacyclo[11.11.0.02,10.04,8.014,22.017,21]tetracosa-1(13),2,4(8),9,11,14(22),15,17(21)-octaene |
| CS-0022888 |
| HY-N3000 |
| PD166537 |
Protein Targets (1)
Inhibition Measurements
Biological Processes (14)
Molecular Functions (10)
Ceullar Components (13)
Bioassays (3)
| Assay ID | Title | Year | Journal | Article |
|---|
| AID1694962 | Antiproliferative activity against human H1975 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay | 2020 | RSC medicinal chemistry, Feb-01, Volume: 11, Issue:2
| The synthesis and biological evaluation of sanguinarine derivatives as anti-non-small cell lung cancer agents. |
| AID1694961 | Antiproliferative activity against human A549 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay | 2020 | RSC medicinal chemistry, Feb-01, Volume: 11, Issue:2
| The synthesis and biological evaluation of sanguinarine derivatives as anti-non-small cell lung cancer agents. |
| AID1350115 | Inhibition of human erythrocyte AChE using S-acetylthiocholine iodide as substrate pretreated for 20 mins followed by substrate addition measured after 30 mins by Ellman's method | 2018 | Journal of natural products, 02-23, Volume: 81, Issue:2
| Mucroniferanines A-G, Isoquinoline Alkaloids from Corydalis mucronifera. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Research
Studies (10)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (30.00) | 29.6817 |
| 2010's | 4 (40.00) | 24.3611 |
| 2020's | 3 (30.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Market Indicators
Research Demand Index: 12.23
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| Metric | This Compound (vs All) |
|---|
| Research Demand Index | 12.23 (24.57) | | Research Supply Index | 2.40 (2.92) | | Research Growth Index | 4.63 (4.65) | | Search Engine Demand Index | 0.00 (26.88) | | Search Engine Supply Index | 0.00 (0.95) |
| |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 10 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |