Page last updated: 2024-12-05

furfurylamine

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Cross-References

ID SourceID
PubMed CID3438
CHEMBL ID3561633
MeSH IDM0405437

Synonyms (76)

Synonym
(furan-2-yl)methanamine
EN300-17953
nsc49136
usaf q-1
methylamine, 1-(2-furyl)-
617-89-0
2-(aminomethyl)furan
2-furanmethylamine
2-furanmethanamine
2-furfurylamine
wln: t5oj b1z
.alpha.-furfurylamine
furfurylamine
nsc-49136
nsc-61168
nsc61168
nsc 49136
(2-furylmethyl)amine
brn 0001614
nsc 61168
un2526
einecs 210-536-9
ai3-25428
alpha-furfurylamine
2-furylmethylamine
2-furylmethanamine
furfurylamine, >=99%
F0091
2-aminomethylfuran
furan-2-ylmethanamine
AKOS000119304
BBL011620
1-(furan-2-yl)methanamine
STL163341
5-18-09-00541 (beilstein handbook reference)
86gan59f7r ,
unii-86gan59f7r
furfurylamine [un2526] [flammable liquid]
ec 210-536-9
FT-0626583
furan-2-methylamine
1-(2-furyl)methanamine
furan-2-ylmethylamine
furylmethylamine
2-furylmethlamine
furan-2-ylmethaneamine
c-furan-2-yl-methylamine
2-furanylmethanamine
2-furanylmethylamine
2-aminomethyl-furan
furfuryl amine
2-furylmethyl amine
(furan-2-yl)methylamine
furan-2-yhnethylamine
(2-furanylmethyl)amine
2-furylmethanamine #
un 2526
tox21_304050
dtxcid6030867
NCGC00357257-01
cas-617-89-0
dtxsid6052295 ,
STR00639
W-109579
PS-9340
CHEMBL3561633 ,
furanmethanamine
F2190-0395
mfcd00003258
bdbm50195324
CS-0015389
Q5509528
1-amino-4-methylpyridinium iodide
10.14272/DDRPCXLAQZKBJP-UHFFFAOYSA-N.1
doi:10.14272/ddrpcxlaqzkbjp-uhfffaoysa-n.1
AT17186

Research Excerpts

Overview

Furylamine is a key furan-based compound for manufacturing perfumes, fibers, additives, medicines and agrochemicals.

ExcerptReferenceRelevance
"Furfurylamine is a key furan-based compound for manufacturing perfumes, fibers, additives, medicines and agrochemicals. "( An efficient and sustainable furfurylamine production from biomass-derived furfural by a robust mutant ω-transaminase biocatalyst.
Di, J; He, YC; Li, Q; Ma, C, 2023
)
2.64

Dosage Studied

ExcerptRelevanceReference
"1%) at 35 °C for 12 h through in situ removal of the amino transfer by-products of the amine donor, greatly reducing amine donor dosage (from D-Ala/5-HMF = 16/1 to D-Ala/5-HMF = 2/1, mol/mol) and improving the productivity of HMFA (0."( Efficient production of hydroxymethyl-2-furfurylamine by chemoenzymatic cascade catalysis of bread waste in a sustainable approach.
Chai, H; He, YC; Li, Q; Ma, C; Wu, C, 2023
)
1.18
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Protein Targets (4)

Potency Measurements

ProteinTaxonomyMeasurementAverage (µ)Min (ref.)Avg (ref.)Max (ref.)Bioassay(s)
retinoic acid nuclear receptor alpha variant 1Homo sapiens (human)Potency33.99480.003041.611522,387.1992AID1159552; AID1159555
estrogen-related nuclear receptor alphaHomo sapiens (human)Potency67.31070.001530.607315,848.9004AID1224841; AID1224848; AID1259403
v-jun sarcoma virus 17 oncogene homolog (avian)Homo sapiens (human)Potency1.09620.057821.109761.2679AID1159526
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Inhibition Measurements

ProteinTaxonomyMeasurementAverageMin (ref.)Avg (ref.)Max (ref.)Bioassay(s)
ReninHomo sapiens (human)IC50 (µMol)300.00000.00000.77968.2000AID1320598
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Biological Processes (18)

Processvia Protein(s)Taxonomy
kidney developmentReninHomo sapiens (human)
mesonephros developmentReninHomo sapiens (human)
angiotensin maturationReninHomo sapiens (human)
renin-angiotensin regulation of aldosterone productionReninHomo sapiens (human)
proteolysisReninHomo sapiens (human)
regulation of blood pressureReninHomo sapiens (human)
male gonad developmentReninHomo sapiens (human)
hormone-mediated signaling pathwayReninHomo sapiens (human)
response to lipopolysaccharideReninHomo sapiens (human)
response to immobilization stressReninHomo sapiens (human)
drinking behaviorReninHomo sapiens (human)
regulation of MAPK cascadeReninHomo sapiens (human)
cell maturationReninHomo sapiens (human)
amyloid-beta metabolic processReninHomo sapiens (human)
response to cAMPReninHomo sapiens (human)
response to cGMPReninHomo sapiens (human)
cellular response to xenobiotic stimulusReninHomo sapiens (human)
juxtaglomerular apparatus developmentReninHomo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Molecular Functions (5)

Processvia Protein(s)Taxonomy
aspartic-type endopeptidase activityReninHomo sapiens (human)
signaling receptor bindingReninHomo sapiens (human)
insulin-like growth factor receptor bindingReninHomo sapiens (human)
protein bindingReninHomo sapiens (human)
peptidase activityReninHomo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Ceullar Components (4)

Processvia Protein(s)Taxonomy
extracellular regionReninHomo sapiens (human)
extracellular spaceReninHomo sapiens (human)
plasma membraneReninHomo sapiens (human)
apical part of cellReninHomo sapiens (human)
extracellular spaceReninHomo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Bioassays (1)

Assay IDTitleYearJournalArticle
AID1320598Inhibition of human recombinant renin expressed in FreeStyle 293 expression system using FITC-epsilonAcp-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu-Val-Ile-His-Asn-Arg-NH2 as substrate preincubated for 15 mins followed by substrate addition measured after 302016Bioorganic & medicinal chemistry, 11-15, Volume: 24, Issue:22
Novel approach of fragment-based lead discovery applied to renin inhibitors.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (20)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (15.00)29.6817
2010's7 (35.00)24.3611
2020's10 (50.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 47.87

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be strong demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index47.87 (24.57)
Research Supply Index3.04 (2.92)
Research Growth Index4.97 (4.65)
Search Engine Demand Index69.56 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (47.87)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other20 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]