Assay ID | Title | Year | Journal | Article |
AID1347129 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Confirmatory screen for SK-N-SH cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
AID1745845 | Primary qHTS for Inhibitors of ATXN expression | | | |
AID1347116 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Confirmatory screen for SJ-GBM2 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
AID1347123 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Confirmatory screen for Rh41 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
AID1347424 | RapidFire Mass Spectrometry qHTS Assay for Modulators of WT P53-Induced Phosphatase 1 (WIP1) | 2019 | The Journal of biological chemistry, 11-15, Volume: 294, Issue:46
| Physiologically relevant orthogonal assays for the discovery of small-molecule modulators of WIP1 phosphatase in high-throughput screens. |
AID1347114 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Confirmatory screen for DAOY cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
AID1508630 | Primary qHTS for small molecule stabilizers of the endoplasmic reticulum resident proteome: Secreted ER Calcium Modulated Protein (SERCaMP) assay | 2021 | Cell reports, 04-27, Volume: 35, Issue:4
| A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. |
AID1347105 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for MG 63 (6-TG R) cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
AID1296008 | Cytotoxic Profiling of Annotated Libraries Using Quantitative High-Throughput Screening | 2020 | SLAS discovery : advancing life sciences R & D, 01, Volume: 25, Issue:1
| Cytotoxic Profiling of Annotated and Diverse Chemical Libraries Using Quantitative High-Throughput Screening. |
AID1347125 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Confirmatory screen for Rh18 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
AID1347106 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for control Hh wild type fibroblast cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
AID1347119 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Confirmatory screen for MG 63 (6-TG R) cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
AID1347098 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for SK-N-SH cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
AID1347118 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Confirmatory screen for TC32 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
AID1347094 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for BT-37 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
AID1347096 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for U-2 OS cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
AID1347128 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Confirmatory screen for OHS-50 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
AID1347107 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for Rh30 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
AID1347095 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for NB-EBc1 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
AID1347104 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for RD cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
AID1347097 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for Saos-2 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
AID1347089 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for TC32 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
AID1347412 | qHTS assay to identify inhibitors of the type 1 interferon - major histocompatibility complex class I in skeletal muscle: Counter screen cell viability and HiBit confirmation | 2020 | ACS chemical biology, 07-17, Volume: 15, Issue:7
| High-Throughput Screening to Identify Inhibitors of the Type I Interferon-Major Histocompatibility Complex Class I Pathway in Skeletal Muscle. |
AID1347093 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for SK-N-MC cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
AID1347126 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Confirmatory screen for Rh30 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
AID1347102 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for Rh18 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
AID1347086 | qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lymphocytic Choriomeningitis Arenaviruses (LCMV): LCMV Primary Screen - GLuc reporter signal | 2020 | Antiviral research, 01, Volume: 173 | A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity. |
AID1347103 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for OHS-50 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
AID1347112 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Confirmatory screen for BT-12 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
AID1347101 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for BT-12 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
AID1347407 | qHTS to identify inhibitors of the type 1 interferon - major histocompatibility complex class I in skeletal muscle: primary screen against the NCATS Pharmaceutical Collection | 2020 | ACS chemical biology, 07-17, Volume: 15, Issue:7
| High-Throughput Screening to Identify Inhibitors of the Type I Interferon-Major Histocompatibility Complex Class I Pathway in Skeletal Muscle. |
AID1347110 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Confirmatory screen for A673 cells) | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
AID1347092 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for A673 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
AID651635 | Viability Counterscreen for Primary qHTS for Inhibitors of ATXN expression | | | |
AID1347100 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for LAN-5 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
AID1347425 | Rhodamine-PBP qHTS Assay for Modulators of WT P53-Induced Phosphatase 1 (WIP1) | 2019 | The Journal of biological chemistry, 11-15, Volume: 294, Issue:46
| Physiologically relevant orthogonal assays for the discovery of small-molecule modulators of WIP1 phosphatase in high-throughput screens. |
AID1347121 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Confirmatory screen for control Hh wild type fibroblast cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
AID1347099 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for NB1643 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
AID1347082 | qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lassa (LASV) Arenavirus: LASV Primary Screen - GLuc reporter signal | 2020 | Antiviral research, 01, Volume: 173 | A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity. |
AID1347122 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Confirmatory screen for U-2 OS cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
AID1347117 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Confirmatory screen for BT-37 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
AID1347113 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Confirmatory screen for LAN-5 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
AID1347083 | qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lassa (LASV) Arenavirus: Viability assay - alamar blue signal for LASV Primary Screen | 2020 | Antiviral research, 01, Volume: 173 | A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity. |
AID1347154 | Primary screen GU AMC qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
AID1347111 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Confirmatory screen for SK-N-MC cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
AID1347109 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Confirmatory screen for NB1643 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
AID1347108 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for Rh41 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
AID1347115 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Confirmatory screen for NB-EBc1 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
AID1347091 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for SJ-GBM2 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
AID1347124 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Confirmatory screen for RD cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
AID1347090 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for DAOY cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
AID1347127 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Confirmatory screen for Saos-2 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
AID504749 | qHTS profiling for inhibitors of Plasmodium falciparum proliferation | 2011 | Science (New York, N.Y.), Aug-05, Volume: 333, Issue:6043
| Chemical genomic profiling for antimalarial therapies, response signatures, and molecular targets. |
AID1346986 | P-glycoprotein substrates identified in KB-3-1 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5
| A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
AID1346987 | P-glycoprotein substrates identified in KB-8-5-11 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5
| A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
AID1132960 | Antiplaque activity against Actinomyces viscosus M-100-2000 assessed as growth inhibition of adherent cells on saliva coated bovine tooth slabs | 1978 | Journal of medicinal chemistry, Aug, Volume: 21, Issue:8
| In vitro antiplaque properties of a series of alkyl bis(biguanides). |
AID95887 | Minimum inhibitory concentration against Klebsiella pneumonia 39645 | 1984 | Journal of medicinal chemistry, Nov, Volume: 27, Issue:11
| Bispyridinamines: a new class of topical antimicrobial agents as inhibitors of dental plaque. |
AID708185 | Toxicity in yeast harboring erg6delta expressing human DHFR-fused amyloid beta (1 to 42) at 10 uM | 2012 | Journal of medicinal chemistry, Nov-26, Volume: 55, Issue:22
| Discovery of novel inhibitors of amyloid β-peptide 1-42 aggregation. |
AID162736 | Minimum antimicrobial inhibitory concentration against Proteus mirabilis MGH-1 | 1984 | Journal of medicinal chemistry, Nov, Volume: 27, Issue:11
| Bispyridinamines: a new class of topical antimicrobial agents as inhibitors of dental plaque. |
AID1063194 | Inhibition of SARS coronavirus PL-protease | 2014 | Bioorganic & medicinal chemistry, Jan-01, Volume: 22, Issue:1
| Identification of novel drug scaffolds for inhibition of SARS-CoV 3-Chymotrypsin-like protease using virtual and high-throughput screenings. |
AID1063205 | Inhibition of SARS coronavirus 3C-like protease using 5-FAM-TSATLQSGFRK(QXL520)-NH2 as substrate preincubated for 5 mins followed by substrate addition measured after 6 mins by FRET assay | 2014 | Bioorganic & medicinal chemistry, Jan-01, Volume: 22, Issue:1
| Identification of novel drug scaffolds for inhibition of SARS-CoV 3-Chymotrypsin-like protease using virtual and high-throughput screenings. |
AID201779 | Compound is evaluated for the effect of saliva upon the antiplaque activity at 50% of saliva and at 0.01 percentage of compound | 1984 | Journal of medicinal chemistry, Nov, Volume: 27, Issue:11
| Bispyridinamines: a new class of topical antimicrobial agents as inhibitors of dental plaque. |
AID209594 | Minimum plaque inhibitory concentration using a standard test organism, Streptococcus mutans OMZ-61 | 1984 | Journal of medicinal chemistry, Nov, Volume: 27, Issue:11
| Bispyridinamines: a new class of topical antimicrobial agents as inhibitors of dental plaque. |
AID201772 | Compound is evaluated for the effect of saliva upon the antiplaque activity at 0% of saliva and at 0.01 percentage of compound; - = No plaque accumulation | 1984 | Journal of medicinal chemistry, Nov, Volume: 27, Issue:11
| Bispyridinamines: a new class of topical antimicrobial agents as inhibitors of dental plaque. |
AID708187 | Cytotoxicity against human HeLa cells after 24 hrs by XTT assay | 2012 | Journal of medicinal chemistry, Nov-26, Volume: 55, Issue:22
| Discovery of novel inhibitors of amyloid β-peptide 1-42 aggregation. |
AID1132961 | Antibacterial activity against wild type Streptococcus mutans 6715-13 assessed as growth inhibition by tube dilution assay | 1978 | Journal of medicinal chemistry, Aug, Volume: 21, Issue:8
| In vitro antiplaque properties of a series of alkyl bis(biguanides). |
AID70080 | Minimum inhibitory concentration against Escherichia coli (Vogel) | 1984 | Journal of medicinal chemistry, Nov, Volume: 27, Issue:11
| Bispyridinamines: a new class of topical antimicrobial agents as inhibitors of dental plaque. |
AID708189 | Inhibition of aggregation of amyloid beta (17 to 40) assessed as fibril formation at 100 uM measured up to 24 hrs by transmission electron microscopic analysis | 2012 | Journal of medicinal chemistry, Nov-26, Volume: 55, Issue:22
| Discovery of novel inhibitors of amyloid β-peptide 1-42 aggregation. |
AID1057175 | Inhibition of Bcl-xL (1 to 206, delta 45 to 84)-BAK (unknown origin) protein interaction by fluorescence polarization assay | 2013 | Bioorganic & medicinal chemistry, Dec-01, Volume: 21, Issue:23
| Synthesis and biochemical evaluation of highly enantiomerically pure (R,R)- and (S,S)-alexidine. |
AID201948 | Compound is evaluated for the effect of saliva upon the staining potential at 0% of saliva and at 0.01 percentage of compound; + = Slight staining | 1984 | Journal of medicinal chemistry, Nov, Volume: 27, Issue:11
| Bispyridinamines: a new class of topical antimicrobial agents as inhibitors of dental plaque. |
AID201933 | Compound is evaluated for the effect of saliva upon the antiplaque activity at 0% of saliva and at 0.05 percentage of compound; + = Slight staining | 1984 | Journal of medicinal chemistry, Nov, Volume: 27, Issue:11
| Bispyridinamines: a new class of topical antimicrobial agents as inhibitors of dental plaque. |
AID201761 | Compound is evaluated for the growth inhibition of Streptococcus mutans OMZ-61 | 1984 | Journal of medicinal chemistry, Nov, Volume: 27, Issue:11
| Bispyridinamines: a new class of topical antimicrobial agents as inhibitors of dental plaque. |
AID708191 | Inhibition of aggregation of amyloid beta (17 to 40) assessed as fibril formation at 100 uM measured up to 13 hrs by high throughput thioflavin-T binding assay | 2012 | Journal of medicinal chemistry, Nov-26, Volume: 55, Issue:22
| Discovery of novel inhibitors of amyloid β-peptide 1-42 aggregation. |
AID207630 | Minimum antimicrobial inhibitory concentration against Staphylococcus aureus | 1984 | Journal of medicinal chemistry, Nov, Volume: 27, Issue:11
| Bispyridinamines: a new class of topical antimicrobial agents as inhibitors of dental plaque. |
AID201774 | Compound is evaluated for the effect of saliva upon the antiplaque activity at 0% of saliva and at 0.05 percentage of compound; - = No plaque accumulation | 1984 | Journal of medicinal chemistry, Nov, Volume: 27, Issue:11
| Bispyridinamines: a new class of topical antimicrobial agents as inhibitors of dental plaque. |
AID1132959 | Antiplaque activity against wild type Streptococcus mutans 6715-13 assessed as growth inhibition of adherent cells on saliva coated bovine tooth slabs | 1978 | Journal of medicinal chemistry, Aug, Volume: 21, Issue:8
| In vitro antiplaque properties of a series of alkyl bis(biguanides). |
AID1063204 | Inhibition of SARS coronavirus 3C-like protease using 5-FAM-TSATLQSGFRK(QXL520)-NH2 as substrate preincubated for 5 mins followed by substrate addition measured after 6 mins by FRET assay in presence of GSH | 2014 | Bioorganic & medicinal chemistry, Jan-01, Volume: 22, Issue:1
| Identification of novel drug scaffolds for inhibition of SARS-CoV 3-Chymotrypsin-like protease using virtual and high-throughput screenings. |
AID1132963 | Antibacterial activity against Actinomyces viscosus M-100-2000 assessed as growth inhibition by tube dilution assay | 1978 | Journal of medicinal chemistry, Aug, Volume: 21, Issue:8
| In vitro antiplaque properties of a series of alkyl bis(biguanides). |
AID1063201 | Binding affinity to SARS coronavirus 3C-like protease using 5-FAM-TSATLQSGFRK(QXL520)-NH2 as substrate by SPR analysis | 2014 | Bioorganic & medicinal chemistry, Jan-01, Volume: 22, Issue:1
| Identification of novel drug scaffolds for inhibition of SARS-CoV 3-Chymotrypsin-like protease using virtual and high-throughput screenings. |
AID201780 | Compound is evaluated for the effect of saliva upon the antiplaque activity at 50% of saliva and at 0.025 percentage of compound; - = No plaque accumulation | 1984 | Journal of medicinal chemistry, Nov, Volume: 27, Issue:11
| Bispyridinamines: a new class of topical antimicrobial agents as inhibitors of dental plaque. |
AID1132962 | Antibacterial activity against Actinomyces naeslundii ATCC 12104 assessed as growth inhibition by tube dilution assay | 1978 | Journal of medicinal chemistry, Aug, Volume: 21, Issue:8
| In vitro antiplaque properties of a series of alkyl bis(biguanides). |
AID201939 | Compound is evaluated for the effect of saliva upon the antiplaque activity at 50% of saliva and at 0.025 percentage of compound; - = No staining | 1984 | Journal of medicinal chemistry, Nov, Volume: 27, Issue:11
| Bispyridinamines: a new class of topical antimicrobial agents as inhibitors of dental plaque. |
AID164401 | Minimum antimicrobial inhibitory concentration against Pseudomonas aeruginosa MGH-2 | 1984 | Journal of medicinal chemistry, Nov, Volume: 27, Issue:11
| Bispyridinamines: a new class of topical antimicrobial agents as inhibitors of dental plaque. |
AID70081 | Antimicrobial minimum inhibitory concentration against Escherichia coli 100/B22 | 1984 | Journal of medicinal chemistry, Nov, Volume: 27, Issue:11
| Bispyridinamines: a new class of topical antimicrobial agents as inhibitors of dental plaque. |
AID201760 | Compound is evaluated for the inhibition of plaque-forming enzyme of Streptococcus mutans OMZ-61 | 1984 | Journal of medicinal chemistry, Nov, Volume: 27, Issue:11
| Bispyridinamines: a new class of topical antimicrobial agents as inhibitors of dental plaque. |
AID1854971 | Antimicrobial activity against Mycobacterium tuberculosis H37Rv incubated for 24 hrs and measured by MTT assay | 2022 | Bioorganic & medicinal chemistry, 10-01, Volume: 71 | Drug screening approach against mycobacterial fatty acyl-AMP ligase FAAL32 renews the interest of the salicylanilide pharmacophore in the fight against tuberculosis. |
AID1132958 | Antiplaque activity against Actinomyces naeslundii ATCC 12104 assessed as growth inhibition of adherent cells on saliva coated bovine tooth slabs | 1978 | Journal of medicinal chemistry, Aug, Volume: 21, Issue:8
| In vitro antiplaque properties of a series of alkyl bis(biguanides). |
AID201938 | Compound is evaluated for the effect of saliva upon the antiplaque activity at 50% of saliva and at 0.01 percentage of compound; - = No staining | 1984 | Journal of medicinal chemistry, Nov, Volume: 27, Issue:11
| Bispyridinamines: a new class of topical antimicrobial agents as inhibitors of dental plaque. |
AID201932 | Compound is evaluated for the effect of saliva upon the antiplaque activity at 0% of saliva and at 0.025 percentage of compound; + = Slight staining | 1984 | Journal of medicinal chemistry, Nov, Volume: 27, Issue:11
| Bispyridinamines: a new class of topical antimicrobial agents as inhibitors of dental plaque. |
AID70083 | Antimicrobial minimum inhibitory concentration against Escherichia coli AB1932-1 | 1984 | Journal of medicinal chemistry, Nov, Volume: 27, Issue:11
| Bispyridinamines: a new class of topical antimicrobial agents as inhibitors of dental plaque. |
AID708190 | Inhibition of aggregation of amyloid beta (17 to 40) assessed as fibril formation at 100 uM measured up to 10 hrs by turbidimetry assay | 2012 | Journal of medicinal chemistry, Nov-26, Volume: 55, Issue:22
| Discovery of novel inhibitors of amyloid β-peptide 1-42 aggregation. |
AID201773 | Compound is evaluated for the effect of saliva upon the antiplaque activity at 0% of saliva and at 0.025 percentage of compound; - = No plaque accumulation | 1984 | Journal of medicinal chemistry, Nov, Volume: 27, Issue:11
| Bispyridinamines: a new class of topical antimicrobial agents as inhibitors of dental plaque. |
AID1440399 | Antibiofilm activity against Candida albicans SC5314 clinical isolates after 24 hrs by XTT assay | 2017 | Journal of medicinal chemistry, 03-23, Volume: 60, Issue:6
| Tackling Fungal Resistance by Biofilm Inhibitors. |
AID201781 | Compound is evaluated for the effect of saliva upon the antiplaque activity at 50% of saliva and at 0.05 percentage of compound; - = No plaque accumulation | 1984 | Journal of medicinal chemistry, Nov, Volume: 27, Issue:11
| Bispyridinamines: a new class of topical antimicrobial agents as inhibitors of dental plaque. |
AID1063210 | Inhibition of SARS coronavirus 3C-like protease using 5-FAM-TSATLQSGFRK(QXL520)-NH2 as substrate | 2014 | Bioorganic & medicinal chemistry, Jan-01, Volume: 22, Issue:1
| Identification of novel drug scaffolds for inhibition of SARS-CoV 3-Chymotrypsin-like protease using virtual and high-throughput screenings. |
AID201940 | Compound is evaluated for the effect of saliva upon the antiplaque activity at 50% of saliva and at 0.05 percentage of compound; - = No staining | 1984 | Journal of medicinal chemistry, Nov, Volume: 27, Issue:11
| Bispyridinamines: a new class of topical antimicrobial agents as inhibitors of dental plaque. |
AID540299 | A screen for compounds that inhibit the MenB enzyme of Mycobacterium tuberculosis | 2010 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 20, Issue:21
| Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. |
AID588519 | A screen for compounds that inhibit viral RNA polymerase binding and polymerization activities | 2011 | Antiviral research, Sep, Volume: 91, Issue:3
| High-throughput screening identification of poliovirus RNA-dependent RNA polymerase inhibitors. |
AID1159550 | Human Phosphogluconate dehydrogenase (6PGD) Inhibitor Screening | 2015 | Nature cell biology, Nov, Volume: 17, Issue:11
| 6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling. |
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |